Top 10 Life Science Angel Investors in Japan (September 2026)

Portfolio highlights

• digzyme — Digzyme develops new enzymatic processes using bioinformatics. The company automates various stages of analysis related to the development of enzymes and bioprocesses using their core bioinformatics technology and further optimize using accumulated data.
• Varinos — Varinos is a clinical laboratory contract analysis company that is a partner of medical institutions. Varinos provides genomic testing development and contract analysis services using the latest technology, the next-generation sequencer.
• Metagen Therapeutics — Metagen Therapeutics (MGTx) is a clinical-stage company operating Japan’s first GMP-compliant manufacturing platform for fecal microbiota transplantation (FMT) therapies. The company combines proprietary paired metagenomic datasets with AI/ML-driven donor-recipient matching to advance precision microbiome medicine across ulcerative colitis,immuno-oncology, and neurodegenerative disease. Headquartered in Tsuruoka, Japan, MGTx leverages a cross-border regulatory strategy spanning PMDA and FDA pathways, positioning it as a platform bridging Japanese clinical innovation with global market access.

Portfolio highlights

• Morus — Morus is a university-based biotech startup developing functional food ingredients from silkworms to address global health and nutrition challenges.
• Epicbase — Epicbase is an AI-based automatic voice transcription service based on voice recognition technology.
• Somewhere — Somewhere is engaged in the travel and transportation business.

Portfolio highlights

• MoonJapan — MoonJapan is an educational impact startup that offers a variety of programs and thorough assistance.
• Memory Lab — Memory Lab is a research laboratory that offers AI paper analysis and development solutions.
• ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .

Portfolio highlights

• digzyme — Digzyme develops new enzymatic processes using bioinformatics. The company automates various stages of analysis related to the development of enzymes and bioprocesses using their core bioinformatics technology and further optimize using accumulated data.

Portfolio highlights

• Modalis Therapeutics — Modalis Therapeutics Corporation is an biotech company focusing on developing transformative therapeutics for unmet medical needs using its proprietary technologies on CRISPR and protein engineering platforms. The company has a strong foundation on intellectual property licensed from the University of Tokyo.

Portfolio highlights

• Helpfeel — Our vision is to make saving, sharing, and exploring ideas as natural as breathing. On this journey we're humbled to be helping millions around the world from solo makers to university research labs, from gamers to pro designers, and large to small teams like ours.
• HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.

Portfolio highlights

• Kaimak — Kaymak is a recruitment platform that focuses on creating a recruitment website, planning a recruitment strategy, and managing candidates.
• D-Chain — D-Chain offers services related to IT development and production in the Web3 and Web2 fields.
• Rayout — Rayout is a business consulting company that provides creative content development, recruitment videos, and web production services.

Portfolio highlights

• Monoun — Mono.un provides users with opportunities to meet authors and collaborate on tales and specializes in bringing exciting experiences full of stories of Japanese culture to the world.
• Memory Lab — Memory Lab is a research laboratory that offers AI paper analysis and development solutions.

Portfolio highlights

• Go Visions — Go Visions engages in the edutainment tech for children and human resources services.
• Ai-Dounyu.com — Ai-Dounyu.com is a platform that helps organizations looking to integrate AI choose their ideal AI implementation partner for free.
• Compass — Compass is a Solve problems in the local labor market with Consultation x Technology

Portfolio highlights

• GPx — GPx is a biotech company that revolutionizes remote chronic disease management with bloodless blood tests. It is dedicated to transforming the standard of care of cardiorenal diseases and enabling patients to better understand their condition, much like the continuous glucose monitor has transformed diabetes care.The company was founded in 2020and is based in Boston, Massachusetts.
• AnotherBall — AnotherBall is a blockchain startup that combines entertainment and blockchain.
• SBX Corporation — AI R&D: Deep learning, Machine learning, Automation, Text mining. Development, customization and maintenance of software platforms for drug discovery and life science research.