Top 50 Medical Angel Investors in United States (October 2026)

Portfolio highlights

• Humera — Humera - AI CAPTCHA That Knows You're Human
• Allonic — Allonic is a robotics hardware company pioneering 3D Tissue Braiding, a new manufacturing platform for producing integrated, compliant, bio-inspired robotic bodies through a single, fully automated production process. By eliminating assembly-heavy designs and supply-chain complexity, Allonic enables significantly faster iteration, lower costs, andsafer, more dexterous robots to be built. Originally founded from Hungary and operating internationally with a US HQ and a growing team of 15, Allonic is building the hardware foundation for the next generation of intelligent machines.
• Heywa Labs — Two products, one engine. Heywa Studio for businesses, Heywa for anyone with a question worth following.

Portfolio highlights

• The Beans — The Beans offers a software application platform that creates personalized cash flow plans designed for its users. The Beans is Simplifying the path to financial balance through design and technology so that people can focus on what they love.
• NextSense — Introducing NextSense Smartbuds: EEG-powered earbuds that go beyond sleep tracking. Backed by science, Smartbuds provide real-time insights to help you achieve deeper, more restorative sleep. Comfortable, intuitive, and easy to use, Smartbuds empower you to wake up your best self.
• Openwater — OPENWATER - THE FUTURE OF NEURAL DIAGNOSTICS IN THE PALM OF YOUR HAND.

Portfolio highlights

• Nix, Inc. — Wearable single-use hydration sensor for athletes, soldiers, and laborers that measures hydration levels and informs when, what, and how much to drink.
• The Invention Network — ScaleIP is an IP business intelligence platform that helps companies monetize IP.
• Clair Health — Clair Health is building the first noninvasive wearable continuous hormone monitor. Track estrogen, progesterone, LH, FSH, and PdG in real-time. Join the Clair Health waitlist.

Portfolio highlights

• CollX — Snap photos of them and instantly get the current market price. Add them to your collection and track your overall portfolio value.
• Collectors — The infrastructure that powers trust, security, and opportunity in collectibles.
• Iterative Health — Iterative Health is a healthcare technology and services company that focuses on accelerating clinical research to improve patient outcomes through innovative approaches. The company transforms gastrointestinal (GI) care by utilizing AI-driven clinical trials and diagnostics, significantly enhancing access to vital treatments.

Portfolio highlights

• SolveAI —
• Rowspace — Specialized intelligence for investors. Compound your firm's edge. We're hiring!
• Harmattan AI — Building the Future of Autonomous Warfare.

Portfolio highlights

• Scoop — Thrive in a hybrid work environment with Scoop's solutions for Workplace Safety, Workplace Utilization, Team Coordination, Desk Management, and Commute.
• Crosby — The AI Law Firm Built for Execution. Lawyer-assisted AI to review MSAs, DPAs and NDAs in under an hour.
• Overwatch Research — Generate accurate in vivo study data as a part of your efficient, connected R&D.

Portfolio highlights

• Onsetto — Onsetto helps banks and credit unions turn business accounts into primary operating relationships: identify, activate, expand, and retain commercial deposits.
• Bonsai — Bonsai is the first-party marketing intelligence platform that automates profitable growth. Trust your marketing data, make confident decisions, drive revenue.
• Evecxia Therapeutics — Evecxia Therapeutics is dedicated to realizing the therapeutic potential of 5-hydroxytryptophan (5-HTP) for the treatment of mental illness.

Portfolio highlights

• Bluecore Energy — Bluecore Energy is a maritime nuclear energy startup that builds compact, zero-emission small modular reactors (SMRs) on floating barges to democratize access to clean energy. The company develops portable, water-cooled power systems designed to scale and meet the energy demands of heavy maritime operations, coastal communities, and major ports.
• Normal Computing — Normal Computing was founded by former members of the Google Brain Team, Palantir, and X who unlocked AI for some of the largest-scale and most mission-critical production systems, and the industry leading ML frameworks for Probabilistic and Quantum AI.
• Reliable Robotics — Advanced automation will make aircraft safer, more available, more affordable and fundamentally transformative to the way goods and people move around the planet.

Portfolio highlights

• June.ai — Discover June, a digital communication hub that replaces your email experience. June creates a new world for your existing email that gives you more control, interactivity and efficiency.
• Panthalassa — We're harnessing renewable energy in the open ocean and delivering it around the world. Engineered in Portland, Oregon.
• Factory — Factory is bringing autonomy to software engineering.

Portfolio highlights

• tbh — tbh is a developer of a mobile application designed to provide anonymous feedback to friends. The company's mobile application facilitates asking or answering questions, open text fields and invite abuse when combined with anonymity, enabling users to say things without repercussions and feel better about themselves from the positive feedbackon social networks.
• Golden — Golden is a developer of a self-constructing knowledge database used to accelerate discovery and education. The company uses and leverages human effort by using machine intelligence to make the process of gathering and communicating knowledge simpler.It combines a powerful search across several entities with fine-grain alerts to stay on top ofchanges, and semi-automatic research assistance for gaps in knowledge that enable people in organizations to stay current, understand and leverage the latest trends in their industry.
• Crossing — Crossing Media is a live broadcast e-commerce service company that builds awareness, engagement, and sales through live-stream shopping.

Portfolio highlights

• Replit — Replit is a simple yet powerful online IDE, Editor, Compiler, Interpreter, and REPL. Code, compile, run, and host in 50+ programming languages.
• Revalia Bio — Revalia Bio develops curative drugs for chronic organ-centered disease.
• Future Fields — Future Fields Cellular Agriculture: Serum-Free Growth Media Supplements and Recombinant Proteins - Optimized for the Future of Food.

Portfolio highlights

• Kinema — A social cinema platform for filmmakers and community builders
• Lava — The financial platform for bitcoin. Spend globally with Lava Card while earning bitcoin back, borrow against your bitcoin, earn on dollars, and more.
• Jupiter — Jupiter is a specialized manufacturer of hair, scalp care and dandruff products.

Portfolio highlights

• SilkChart — SilkChart helps growth teams improve campaigns based on what users are doing in product - without relying on expensive data scientists. We do this through a no code analytics tool that combines marketing and product usage data to identify which channels, audiences, and content maximize revenue growth.
• Trace — Trace is an orchestration engine that breaks down existing workflows, assigns repetitive tasks to AI agents and routes the rest to the right people.
• Augmend — Create documentation and an AI assistant from any video.

Portfolio highlights

• Allara — Allara is your all-in-one virtual care team for hormonal, metabolic & gynecological conditions such as PCOS and Endometriosis.
• Systole Health — Join Systole Health and take control of your heart health. Our personalized group virtual care combines expert-led medical treatment with the power of community support.
• Parakeet Health — Parakeet converts patient demand into revenue: verified lift above your own baseline across scheduling, recall, referrals, and no-show recovery. Pay for performance.

Portfolio highlights

• Darvis — Eliminate inventory gaps with AI-powered tracking and real-time healthcare supply visibility.
• Copilot — Start, run, and grow your business with a client portal that streamlines messaging, payments, file-sharing, help centers, custom app access, and more.
• Social Chat — Loup is an intelligent marketing platform that lets you turn your website into a personal shopping experience with interactive video.

Portfolio highlights

• Satellite Bio — Satellite Bio specializes in cell therapy, regenerative medicine, synthetic biology, cell biology, and tissue engineering. It focuses on the development and implementation of proprietary, off-the-shelf, implantable satellite organs as living therapeutic solutions that can transform the lives of millions of patients who suffer from serious diseases.
• Devoted Health — Devoted Health is a new healthcare company serving seniors. Aiming to launch Medicare Advantage plans in 2019, their mission is to build a healthcare solution good enough for Mom. They will be devoted to the health and wellness of their members by helping them navigate the health care system with personal guides, by utilizing world-class technologyto enable a simplified experience, and by partnering with top providers for better health outcomes.
• Shape Therapeutics — Shape Therapeutics (ShapeTX) is a biotechnology company with an end-to-end approach to RNA Gene Therapy, potentially enabling the development of cures in neurodegenerative, metabolic and rare genetic diseases through our breakthrough payload, delivery, and manufacturing platform technologies. Our vision is to facilitate adoption of thesetechnologies throughout the industry to develop effective treatments for as many patients as possible.

Portfolio highlights

• Zanskar — Zanskar Geothermal & Minerals uses custom AI tools and geoscience models to analyze vast amounts of data and pinpoint untapped geothermal hotspots.
• Play Health — Delivering data & AI-driven (peri)menopause care software to improve outcomes today, developing precision medicine infrastructure for tomorrow.
• Dunia Innovation — Catalysing the energy transition.

Portfolio highlights

• Sorare — Global Fantasy Football. Collect limited edition digital collectibles, Manage your team and earn prizes!
• Hoth Intelligence — Hoth Intelligence home page. Space age surgical technology brought down to earth.
• Floating Point Group — Floating Point Group is a trading platform provider offering innovative, industry-leading trade execution and settlement

Portfolio highlights

• Alex AI — Alex is the AI recruiter that puts sourcing, screening, and scheduling on autopilot. Fast-track vetting so you interview the best in days.
• TextQL — TextQL is you personal virtual data analyst, built for enterprise and powered by AI. Ask in natural english and Ana can build insightful analysis, stunning charts, and powerful models, all with enterprise-grade security.
• Raindrop — Trace every run. Auto-fix silent failures. Simulate before shipping.

Portfolio highlights

• Mixlab — Mixlab is a modern pet pharmacy for veterinarians and pet parents. Our technology and customer experience greatly enhance veterinarian processes and ensure that pet parents receive personalized care that delights them.
• Bleximo — bleximo.com is for sale
• Minerva — Get things done faster with simple how-to guides for whatever you want to do online. Created by our community of experts, follow or make your own guide today!

Portfolio highlights

• Grubel — Grubel envisions a future in which each substance creates its own AI, one that understands its surroundings and performs the best work possible within them.
• G5 Labs — G5 is the semantic abstraction layer that makes AI-native software development compilable, mergeable, and governable for enterprises.
• Wafer — Wafer is an AI optimization platform that automatically accelerates AI models by generating efficient custom GPU kernels.

Portfolio highlights

• Estate Media — Real Estate's Biggest Personalities Under one Roof
• Subquadratic — AI lab leading the subquadratic LLM revolution.
• Hidden Studios — Hidden Studios develops and advertises Fortnite Creative games, with 100M+ plays monthly. The company collaborated with prominent brands and creators, including Skydance, Snoop Dogg, and CaseOh, to deliver engaging gaming experiences. Hidden Studios maintains an active presence on YouTube, sharing content related to their Fortnite Creativeendeavors.

Portfolio highlights

• Nada — Finance, Invest and Bank your real estate.
• DigiBuild — Automate your construction supply chain with AI.
• Upright — Meet Upright, the good for you go-to. Our first product is a category-defining high-protein, allergen-free Instant Oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate. Each tasty cup of our oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact.

Portfolio highlights

• SiPhox Health — Painless, 5-minute biomarker testing at home. Clear insights, trend tracking, and a personalized plan built around your results.
• BuildForever — BuildForever build products that feel personal, magical and deeply human.
• Perplexity — Perplexity is a search engine platform that uses artificial intelligence to provide large language models and search engines. The company's platform enables the development of beneficial artificial general intelligence, as well as an open-source environment that is accessible to the public, allowing clients to develop skills and knowledge inartificial intelligence.

Portfolio highlights

• Bryn Pharma — Bryn Pharma is a pharmaceutical company that offers nasal-based epinephrine for anaphylaxis. Its bi-dose intranasal device is an alternative to epinephrine auto-injectors and is needle-free. It is easy to use and portable enabling patients to treat allergic reactions or anaphylactic reactions.
• Beckley Psytech — Our mission is to help people suffering from neurological and psychiatric conditions by developing our pipeline of psychedelic compounds.
• MycoMedica Life Sciences, PBC — Psychedelic Medicines

Portfolio highlights

• Audioshake — AudioShake makes audio interactive, customizable, and accessible by using AI to separate sound recordings into their component parts and stems.
• Catena Labs — Catena is a product studio where we transform complex computing advancements into accessible, practical tools for users and developers. Leveraging AI and web3 technology our aim is to turn innovative ideas into real-world applications that are easy to use.
• NextSense — Introducing NextSense Smartbuds: EEG-powered earbuds that go beyond sleep tracking. Backed by science, Smartbuds provide real-time insights to help you achieve deeper, more restorative sleep. Comfortable, intuitive, and easy to use, Smartbuds empower you to wake up your best self.

Portfolio highlights

• Cardenxe Sotol — Artisanal Small Batch 100% Sotol Spirit Cardenxe Sotol is a terroir-inspired premium craft spirit, distilled from the heart of the Dasylirion plant, in North of Mexico - where it holds a Denomination of Origin. Every label (Desierto and Sierra) honors a different environment in which the plants used to distill grew.
• Terraformation — Terraformation creates partnerships to scale reforestation with hardware, software, and knowledge based solutions.
• Rebellyous Foods — Rebellyous Foods makes crispy, juicy, 100% plant-based nuggets. Your guests will love the taste. Your team will love the simplicity. Get Rebellyous with us!

Portfolio highlights

• Barndoor AI — Barndoor AI offers a centralized governance layer to manage granular access, policy enforcement, and visibility across agentic AI workforce.
• Artemis — Powered by AI, Mona Lee is the fastest, most efficient way for homeowners to go solar. Through a direct-to-consumer approach, Mona Lee’s AI-powered self-serve platform transforms the solar buying experience by eliminating non-stop solicitation calls, lengthy design and evaluation processes, and back-and-forth price negotiations that can take up toweeks. With Mona Lee, customers go from quote to scheduling their installation in minutes. Feel free to visit our website to read customer testimonials and Mona Lee solar reviews.Mona Lee was founded by a group of serial entrepreneurs with decades of experience in clean energy. The company is headquartered in Boston, MA and is proud to serve homeowners nationwide.
• Together AI — Together will enable researchers, developers & companies to leverage and improve artificial intelligence with an intuitive data, models & computation platform.

Portfolio highlights

• Convex — All gas, no breakages. Convex is the reactive backend platform that keeps up with you and your agents.
• FLORA — FLORA is an applied AI HCI company building creative tools.
• Samepage — Building your second brain for product leaders

Portfolio highlights

• Lassie — AI that runs the doctor's office.
• Open Cosmos — Open Cosmos design, build and operate space missions, providing straightforward access to high quality satellite data and insights on a global scale.
• Lightyear — Lightyear is a simple and approachable way to invest your money globally without unnecessary barriers and fees.

Portfolio highlights

• Allara — Allara is your all-in-one virtual care team for hormonal, metabolic & gynecological conditions such as PCOS and Endometriosis.
• Systole Health — Join Systole Health and take control of your heart health. Our personalized group virtual care combines expert-led medical treatment with the power of community support.
• Parakeet Health — Parakeet converts patient demand into revenue: verified lift above your own baseline across scheduling, recall, referrals, and no-show recovery. Pay for performance.

Portfolio highlights

• Unito — Unito is taking on a major problem that people are passionate about solving: they make it easier to collaborate across teams. They don't make users learn new tools and change the way they work. By connecting work management tools, they allow managers, cross-functional teams, departments, and entire companies to benefit from seamlesscollaboration and improved communication. The app syncs projects across a number of tools like Trello, Asana, JIRA, GitHub, Wrike, Zendesk & Hubspot. This is a hard problem of semantics, synchronization, and APIs.
• Delphia — Delphia puts your data to work for you.
• North One — NorthOne is an online Business Account with built-in features to make business banking fast and easy. No overdraft fees. No minimum balance. No hidden fees.

Portfolio highlights

• Medmo — Medmo is an all-encompassing solution for providers to order, schedule, and track medical imaging appointments for their patients. Improve completion rates with less staff burden and lower costs.
• Mevo — Mevo is a healthcare platform that makes people's life simpler by providing everything from a digital prescription with an online purchase option for medicines to be delivered to their homes. Mevo is headquartered in São Paulo, Brazil and was founded in 2017.
• Commons Clinic — Commons Clinic is a group of world class orthopedic surgeons in Los Angeles, CA. Our orthopedic specialists provide expert care from start to finish.

Portfolio highlights

• Osmo Studio — Osmo is an AI-native video editor for product launch videos and motion graphics. Turn ideas, Figma files, and footage into polished, on-brand animations, built as editable code.
• Gravity — The Ad Network for AI
• Instinct — Instinct is an artificial intelligence startup developing AI technology.

Portfolio highlights

• Encellin — Encellin develops a novel thin-film cell encapsulation device for cell-based therapeutics. It has dedicated experts focused on the investigation and advancement of next-generation therapies. It aims to help patients with chronic diseases, starting with Type 1 diabetes. It was founded in 2016 and is headquartered in San Francisco, California.
• Ochre Bio — Ochre Bio is developing therapies for the biggest liver health challenges.
• Arpeggio Bio — We engineer medicine based not on a single target, but the biological network as a whole.

Portfolio highlights

• Bland AI — Transform your enterprise communication with Bland AI. Automate inbound and outbound phone calls using AI that sounds human. Perfect for sales, customer support, and operations with customizable voices and seamless integrations.
• SplitPay — SplitPay is a mobile app that offers credit with a buy now, pay later option.
• Black Ore Technologies — Black Ore's Tax Autopilot is the first AI tax platform for CPAs, offering complete 1040 tax preparation automation to tax professionals, so they can focus on growing their firm.

Portfolio highlights

• Praan — Praan builds the world's most advanced air purification technologies for commercial and industrial applications.
• Prevently — Prevently is a website that provides consumers with physician-reviewed health articles, physician-approved health products, health apps, and telemedicine consultations. These services centralize around an online patient profile that integrates data utilizing APIs from multiple personal health tracking devices.

Portfolio highlights

• Jaunt — >>Why Do We Use People Search?
• Yelp Reservations — Yelp's restaurant technology combines a network of 95 million monthly diners with tools to attract eyeballs and seat diners more efficiently.
• Vaunte — Vaunte is your Fashion, Beauty, Health & Fitness website. We provide you with the latest news and tips straight from the world.

Portfolio highlights

• NavigateAI — An AI copilot for every person in the field. NavigateAI upskills and coaches your team, runs real-time quality control, manages the project in the background, and provides expert knowledge, instantly.
• Preventive — Preventive mission is to determine whether the newest generation of gene editing technologies can be used safely and responsibly to correct devastating genetic conditions for future children.
• Pilgrim — Pioneering a biologically enhanced future for humanity.

Portfolio highlights

• Aria CV — Learn about Aria CV's novel implantable medical device designed to treat pulmonary hypertension (PH). Our elegant device has no battery, pump, or electronics.
• Madorra — Madorra Their goal is empowering women to live fuller, healthier lives. Madorra is working towards changing the paradigm for treating vaginal dryness, by providing a medical device solution to a problem that has previously only been served by pharmaceuticals. They are focused on giving post-menopausal women and breast cancer survivors the power tochoose the non-hormonal treatment option they want.
• Siren Care — Siren Socks help reduce the risk of foot ulcers for patients with diabetes through the early detection of potential injuries.

Portfolio highlights

• EquityNet — EquityNet is a financial services company that specializes in providing solutions in the fields of angel investors, investment banking, business funding, and venture capital. It provides access to thousands of approved, self-accredited investors and has helped entrepreneurs across North America raise over $300MM in equity, debt, and alternativelysourced capital.The company was founded in 2005 and is headquartered in Salt Lake City, Utah.
• RenovoDerm — A medical device company building a line of wound care products that provide a structure for tissue growth and promote faster healing of wounds—while reducing scar tissue. Funding prior to formation: $1.6 million.
• Vascular Genesis — A medical device company laying the foundation for vascular conduit replacement with its line of cell-free, synthetic scaffold products -- with self-healing capabilities that lower the risk of rejection, infection, and stenosis. Funding prior to formation: $2.5 million.

Portfolio highlights

• Emailage — Emailage is a developer of fraud prevention and identity verification technology used to make transactions easier and secure. The company provides multi-faceted predictive solutions with email at the core through key partnerships, proprietary data, and advanced machine-learning technology. It proprietary algorithms in order to provide real-timealerts of risky transactions and delivers a risk score and enable companies to realize significant savings from identifying and stopping fraudulent transactions and improve customer experience.
• Ceevra — Ceevra is an advanced 3D visualization technology for surgeons. Using AI and other innovative computing techniques, Ceevra generates brilliant 3D digital models from standard CT scans and MRIs. Surgeons use the Ceevra 3D models to help educate and counsel patients, to decide on the best surgical approach, and to gain important insights whileoperating.
• TigerGraph — TigerGraph is the leading graph database for real-time AI and analytics. Detect fraud, resolve entities, and uncover hidden connections at enterprise scale.

Portfolio highlights

• Marvin AI — Marvin is a mental health service for physicians. We're ending the one-size-fits-all approach to teletherapy, helping you to set a teletherapy action plan.
• Marley Medical — Our board-certified physicians create your custom care plan, while nurses, pharmacists and health coaches check in and cheer you on to your good-health goals.
• Veracity — Veracity creates a personal skincare experience based on real data about your hormones and biofactors through our Skin + Health test.

Portfolio highlights

• Ambience Healthcare — Experience what it feels like to never have to type or dictate another note again.
• Tonic — From your home, to the world. Sign up now to take lessons from the best musicians in the world.
• General Proximity — The next generation of induced-proximity medicines. We're here to put a dent in the universe.

Portfolio highlights

• Taranis — Taranis offers cutting-edge crop & farm management software for precision agriculture. Increase efficiency and yield. Learn more now.
• Imagene AI — Imagene AI is a pioneer in multimodal foundation models for precision medicine, advancing translational research and clinical development. We make every trial more responsive, every insight more actionable, and every patient journey more personalized.
• MSICS Pharma — MSICS Pharma is a pharmaceutical company that manufactures and produce naturally-sourced Psilocybin for medical purpose.

Portfolio highlights

• Vorflux — Cloud agents that ship production code. An opinionated harness that runs the full SDLC on dedicated machines.
• Aseon Labs — Robotic pitstops for self driving cars. A depot in a box for charging, cleaning & inspecting AVs directly in operating zones. Backed by @ycombinator
• Axiom Trust — Axiom Trust is an AI-powered trust startup that modernises professional trust administration during the "Great Wealth Transfer" of over $100 trillion in assets.

Portfolio highlights

• Ethix360 — ETHIX360 provides Compliance as a Service (CaaS); a simple, affordable answer to employee ethics communication and human resources case management.
• Ash & Erie — Men's clothes designed from scratch for shorter men 5'8" and under. Find men's casual and formal clothing from button-downs, t-shirts, sweaters, denim jeans, chinos, and more. FREE Shipping, Exchanges, and Returns.
• Outlogic — Outlogic is a provider of location data for the retail, real estate, and financial markets. Outlogic has exemplified high standards and best practices for the collection and use of location data while still allowing companies to develop disruptive tools built on a foundation of quality data.

Portfolio highlights

• ImageMoverMD — A patient-centric platform that transforms enterprise imaging workflows.
• Wantable — Launched in 2012, Wantable, Inc. is a discovery e-commerce company that sends customers hand-picked and personalized beauty, fashion accessories, or luxury intimate apparel items.Wantable sends customers on-trend boutique, speciality, and premium products that we feel she would want to discover. Top brands like Kiby's, ncLA, and VincentLongo, along with boutique brands like (PLA) Beauty, Liberty Republic, and Soxxy have partnered with Wantable.
• MediCardia — MediCardia is the first digital health platform that aggregates, organizes and operationalizes comprehensive clinical data for the clinician. MediCardia's virtual care platform serves as a unified and common interface for EHRs and remote technologies including wearables, consumer home medical devices, and implanted cardiac rhythm devices.With embedded video and smart design, our core platform includes the patent-pending HeartChart scoring algorithm, advanced natural language processing (NLP) for data discretization, automated chart preparation, and soon to be launched imaging, a search platform, second opinion, and a proprietary clinical intelligence engine.

Portfolio highlights

• thrie — Transportation
• Alphunt — Login to LinkedIn to keep in touch with people you know, share ideas, and build your career.
• Bite - build your social circle — Bite is a social app focused on creating and facilitating hangouts. So you can build or maintain your social circle

Portfolio highlights

• Catena Labs — Catena is a product studio where we transform complex computing advancements into accessible, practical tools for users and developers. Leveraging AI and web3 technology our aim is to turn innovative ideas into real-world applications that are easy to use.
• Asterix — Asterix offers digital ownership and unlocks new possibilities.
• Cosmology — Cosmology is building a unified developer experience for interchain dApps