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Top 50 Biotech Angel Investors in United States in January 2026

Last updated: Jan 2026 A list of 50 angel investors that invest in Biotech startups based in United states. We rank investors based on the number of investments they made in Biotech companies from United states. We update this investor list every month.

Top 50 Biotech Angel Investors in United States in January 2026

Investor	Biotech United States investments
Milad Alucozai	17
Jeff Dean	12
Jaffray Woodriff	10
Kingsley Advani	9
Jude Gomila	9
Farzad Nazem	9
Sam Altman	8
bumpkins profile	8
Jeff Hammerbacher	7
Sahin Boydas	7
Alice Zhang	7
Paul Buchheit	7
Zach Weinberg	6
Wei Guo	6
Kevin Moore	5
Anne Wojcicki	5
Jim Mellon	5
Evan Cheng	5
Brian Armstrong	5
Erik Peterson	5
Chris Gibson	5
Daniel Curran	5
Fred Ehrsam	5
Elad Gil	5
Balaji Srinivasan	5
Mark Cuban	5
Darian Shirazi	4
Peter Thiel	4
Nat Turner	4
Todd Corenson	4
David R. Walt	4
David Beyer	4
Brad Flora	4
Daren Cotter	4
Ling Wong	4
Brenton Saunders	4
Bill Gates	4
Eric Kwan	4
Max Levchin	4
Bill Gates	4
Esther Dyson	4
Jack Abraham	4
Cory Levy	4
Timothy A. Springer	4
John D'Orazio	4
Avichal Garg	4
Bradley Horowitz	4
Patrick Hsu	3
John Ballantyne	3
Erik Moore	3

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Recognized by Business Insider in 2025 as “one of the top 100 early-stage investors,” Dr. Alucozai has experience translating exceptional science and technology into scalable commercial ventures. Alongside his experience as a founder and operator, he has actively invested in over 100 startups across North America and Europe. He has often been thefirst investor to back high-growth companies like Seqera Labs. Milad began his career as a neuroscientist at the intersection of bioengineering, computational biology, and machine learning, where he commercialized platforms designed to deliver promising medicines to patients more efficiently and safely. His focus as an investor has been to accelerate the journey of groundbreaking discoveries from the lab to the market, particularly in the life sciences sector and related computational fields.Milad is a co-founder and General Partner at Pamir Ventures, an early-stage venture firm that invests in technical pioneers developing B2B companies utilizing AI in antiquated industries. He is also a co-founder of Revalia Bio, which aims to establish a human-centric infrastructure for drug discovery and development. By using non-transplantable human organs donated for research, Revalia offers the scientific community unparalleled insights into patient biology, ultimately aiding in the creation of improved treatments and cures. Throughout his operating and investing career, Milad has played a crucial role in helping founders secure hundreds of millions in capital and facilitating over $1 billion in startup-pharma partnerships. His previous roles include supporting business development at Accenture, Absci, Bit Bio, Numerate, Mekonos, and AstraZeneca. Through Digitalis Commons, he was an Expert in Residence in support of the Advanced Research Projects Agency for Health (ARPA-H), where he aided the US government and ARPA-H mission to enable transformative biomedical and health breakthroughs, providing health solutions through $1.5 billion in non-dilutive investments. He was a National Science Foundation Scholar and Macklin Fellow at Johns Hopkins Medicine. He graduated Phi Beta Kappa with a degree in Neuroscience from Purdue University’s Honors Program, earned a master’s in Immunology and Public Health as a George J. Mitchell Scholar, and holds a doctorate from the Richard M. Fairbanks School of Public Health. Additionally, he completed a Visiting Scholar appointment at the Wyss Institute at Harvard University.

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

Replit — Replit is a simple yet powerful online IDE, Editor, Compiler, Interpreter, and REPL. Code, compile, run, and host in 50+ programming languages.
Future Fields — Future Fields Cellular Agriculture: Serum-Free Growth Media Supplements and Recombinant Proteins - Optimized for the Future of Food.
Endpoint Health — Endpoint Health is a precision-first therapeutics company. By rewriting the molecule-first drug development model, we aim to deliver precision therapies that have the potential to improve outcomes for patients with immune-driven illnesses.

Jeff Dean is the Chief Scientist of Google DeepMind and Google Research. He joined Google in 1999 and has played a pivotal role in shaping the company’s technical foundations. He currently focuses on advancing AI and deep learning research across Google’s research teams.He co-founded and led the Google Brain team, helping drive innovations indeep learning for speech recognition, computer vision, natural language understanding, and a wide range of predictive applications. Over the years, he has co-designed and implemented several generations of Google's core systems, including its web search infrastructure, crawling and indexing pipelines, and advertising technologies such as AdSense for Content.He is also a key contributor to Google's distributed computing infrastructure, having co-designed and implemented systems like MapReduce, BigTable, Spanner, Protocol Buffers, LevelDB, and TensorFlow—one of the most widely used open-source machine learning platforms.Jeff Dean earned his Ph.D. in Computer Science from the University of Washington in 1996. He is a Fellow of the ACM, a member of the U.S. National Academy of Engineering and the American Academy of Arts and Sciences, and a recipient of the ACM-Infosys Foundation Award in the Computing Sciences and the Mark Weiser Award.

Investment focus

Artificial Intelligence, Information Technology, Software
Seed, Series A, Pre-Seed
United States, United Kingdom, Japan

Portfolio highlights

Sophont — Multimodal foundation models for healthcare
Onepot.ai — Onepot.ai offers automated synthesis of small molecules from basic building blocks using a unified, end-to-end process. It generates around fifty distinct compounds in a single workflow, eliminating the need for bespoke methods for each target. The platform employs modular couplings, deprotection, and streamlined purification steps to rapidlyassemble structurally diverse molecules. It supports chemistries that produce both sp²- and sp³-rich frameworks, enabling applications across pharmaceutical, materials, and probe development. By leveraging a catch-and-release purification protocol and iterative building-block assembly, Onepot.ai enables efficient production of complex small-molecule libraries.
Periodic Labs — Periodic Labs develops artificial intelligence systems that simulate and predict the properties of materials using machine learning. The company applies computational models to support the discovery and design of materials used in sectors such as energy, electronics, and infrastructure. It builds tools that aim to reduce the time and costassociated with traditional research and development processes. Periodic Labs uses AI to analyze large-scale scientific data and collaborates with academic and industry partners to support material science research.

Angel Investor located in Charlottesville, VA

Investment focus

Software, Biotechnology, Health Care
Seed, Series A, Angel
United States

Portfolio highlights

Yogi — Yogi's analytics platform lets you easily sift through customer Reviews & Ratings data. Get actionable insights from your product Reviews, Ratings, and Sentiment Analysis to improve your brand reputation and product experiences.
Caju AI — Caju AI revolutionizes customer engagement with Generative AI, boosting your workforce's productivity and providing invaluable business insights. Elevate your customer experience with the power of AI.
Starchive — AI enriched Digital Asset Management designed by creators for creators, to maximize the control and ownership of their content, community, and commerce in the Visual Media Economy.

Kingsley Advani (born October 24, 1993, in London, United Kingdom) is a British tech entrepreneur, investor, and author based in Dubai, United Arab Emirates. He is the Founder and CEO of Allo, an exchange for tokenized stocks managing over $2 billion in tokenized real-world assets, and the founder of Allocations, a fintech platform that has grownto administer more than $2 billion in assets across 30,000+ high-net-worth clients.Advani began his entrepreneurial journey at the age of 13, launching a digital commerce business on eBay, before discovering Bitcoin in 2011 while studying finance and economics. In 2013, he allocated his IBM internship savings into Bitcoin and other emerging cryptocurrencies, becoming an early investor in what later became a multi-billion-dollar asset class. By his mid-twenties, he had invested in more than 200 companies, including unicorns such as SpaceX, Solana, Coinbase, Robinhood, and eToro.In 2017, he co-founded a global investor syndicate that collectively managed more than $4 billion in assets. Two years later, he launched Allocations, a platform providing infrastructure for fund administration, SPVs, and private market investments. CNBC recognized him as the “Blockchain Oracle” for his early insights into cryptocurrency adoption and market trends.Through his ventures, Advani has become a leading voice in fintech, blockchain, tokenization, private markets, and Web3, with frequent speaking engagements at global conferences including the SF Blockchain Summit, Beyond Blocks, Coinfest Asia, and the Ritossa Summit in Dubai. His commentary emphasizes how blockchain and emerging technologies can democratize access to alternative assets and reduce the barriers to launching micro-funds.Advani is also the author of The Blockchain Oracle: How Technology, Finance, and Vision Shape the Future of Global Investing (2025), a book that explores the intersection of blockchain, fintech, and global finance.

Investment focus

FinTech, Financial Services, Biotechnology
Seed, Pre-Seed, Series A
United States, Singapore, United Kingdom

Portfolio highlights

Checkstep — Checkstep is the trusted AI content moderation software that helps global platforms detect harmful content, enforce policies, and stay compliant at scale. Combine powerful automation with human expertise to deliver safe, relevant, and compliant digital experiences.
Allocations — 10,000+ investors and fund managers build, onboard and close funds on Allocations - the fastest and most advanced fund platform in the world
Ashvattha Therapeutics — Ashvattha Therapeutics creates products that selectively target and treat human diseases. Ashvattha enables precision targeting for therapeutics eliminating off-target toxicity, systemic side effects, and immunogenicity seen in other platforms. Ashvattha has a pipeline of nine therapeutics in neurology, oncology, and ophthalmology.

Jude Gomila is currently CEO and Founder of the startup Golden.

Investment focus

Software, Biotechnology, Information Technology
Seed, Pre-Seed, Angel
United States, United Kingdom, Canada

Portfolio highlights

Parcha AI — Parcha is an AI-powered enterprise software that enables businesses to automate their scale compliance and operations.
HockeyStack — HockeyStack enables marketing teams to drive pipeline efficiently and sales teams to close deals faster with modern attribution, holistic buyer journeys, and account insights.
Farmako — Install Farmako app, get a free health ID and get all your medical records safe and secure in one place!

Farzad (Zod) Nazem has been a prolific angel investor and advisor to tech startup companies since his retirement from Yahoo! in 2007. He has invested in more than 60 early stage companies, and sits on the boards of Hand Foundation, and The Nueva School. His area of investment is about two thirds Big Data and Cloud platforms, and one third Healthand Medical. He was the Executive Vice President of Engineering and Chief Technology Officer of Yahoo from 1996 to mid 2007. He helped acquire and integrate over 50 companies and managed over six thousand engineers representing half of the company's employees. Between 1985 and 1996, Mr. Nazem held various software development and management positions at Oracle Corporation culminating in his role as Vice President of Media and Web Server Division. His tenure at Oracle also included membership in the company's Product Division Management Committee, which set overall strategy for Oracle products. Previously, Mr. Nazem was recruited from California Polytechnic State University by Rolm Corporation to be a software engineer in the VLCBX division. At age 19, he earned a B.S. degree in Computer Science with highest honors.

Investment focus

Health Care, Software, Analytics
Seed, Series A, Series B
United States, Canada

Portfolio highlights

Emailage — Emailage is a developer of fraud prevention and identity verification technology used to make transactions easier and secure. The company provides multi-faceted predictive solutions with email at the core through key partnerships, proprietary data, and advanced machine-learning technology. It proprietary algorithms in order to provide real-timealerts of risky transactions and delivers a risk score and enable companies to realize significant savings from identifying and stopping fraudulent transactions and improve customer experience.
Ceevra — Ceevra is an advanced 3D visualization technology for surgeons. Using AI and other innovative computing techniques, Ceevra generates brilliant 3D digital models from standard CT scans and MRIs. Surgeons use the Ceevra 3D models to help educate and counsel patients, to decide on the best surgical approach, and to gain important insights whileoperating.
TigerGraph — TigerGraph is the leading AI-powered graph database. Uncover hidden relationships, run real-time analytics at scale, and power fraud detection, customer 360, and AI

Sam Altman is the CEO and co-founder of OpenAI. He is a Partner of Apollo Projects. Altman was the president of Y Combinator. Sam attended Stanford University.

Investment focus

Software, Artificial Intelligence, Internet
Seed, Series A, Series B
United States, Canada, Ghana

Portfolio highlights

NOYACK — NOYACK builds agentic AI technology for wealth management, starting with NOYACK.ai—the first AI agent for financial literacy - and Prophit.ai , the first opensource AI agent for portfolio optimizations of ALL asset classes. The fintech platform uses autonomous AI to deliver personalized financial guidance and construct tax-optimized portfolioscombining traditional accounts (IRAs, 401(k)s, HSAs) with private market investments in venture capital, fine art, and real estate for Millennials and Gen Z investors
Boom Supersonic — Making the World Dramatically More Accessible
Arcadia Medicine — Arcadia Medicine is a biotechnology company that creates psychedelic medicine to treat mental health issues.

blah - teh software was teh busted and they didn't want to fix it or hire someone to fix it, odd folks, these.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Pre-Seed
United States, Canada, India

Portfolio highlights

Sorare — Global Fantasy Football. Collect limited edition digital collectibles, Manage your team and earn prizes!
Hoth Intelligence — Hoth Intelligence home page. Space age surgical technology brought down to earth.
Floating Point Group — Floating Point Group is a trading platform provider offering innovative, industry-leading trade execution and settlement

Jeff Hammerbacher - Partner & Co-Founder @ Techammer

Investment focus

Software, Artificial Intelligence, Biotechnology
Seed, Series A, Angel
United States

Portfolio highlights

257 — The residential energy data platform
Lamin — Lamin provides an open data platform for biology, enabling tracked data management, streamlined collaboration, and learning at scale.
Inductive Bio — Bringing the data, ML, software, and expertise needed to rapidly solve your most challenging ADMET problems.

Sahin Boydas is a serial entrepreneur who co-founded startups in Silicon Valley.Sahin has built and managed remote teams for over a decade. He founded RemoteTeam.com, which was a payments and HR platform for remote teams, and was acquired by Gusto.He co-founded the movie marketing platform MovieLaLa, and was downloaded by millions with networkpartnerships. Movielala sold it to Gfycat. He co-founded a sticker platform called MojiLaLa and a consumer-facing Augmented Reality app, Leo AR.

Investment focus

Software, Financial Services, FinTech
Seed, Series A, Series B
United States, Mexico, Norway

Portfolio highlights

Warp — Warp is a payroll and compliance tool that makes it easy for founders to hire, onboard, and pay their employees.
Boost Robotics — Boost Robotics combines digital infrastructure with physical agents to revolutionize robotics solutions.
Reach — Reach delivers long-range, wireless power-at-a-distance for defense, industrial, and critical infrastructure use cases. Eliminate manual charging and enable persistent operations with scalable wireless energy solutions.

CEO and Co-founder at Verge Genomics; Angel Investor in Tech-Enabled Bio

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Pre-Seed
United States, United Kingdom

Portfolio highlights

Encellin — Encellin develops a novel thin-film cell encapsulation device for cell-based therapeutics. It has dedicated experts focused on the investigation and advancement of next-generation therapies. It aims to help patients with chronic diseases, starting with Type 1 diabetes. It was founded in 2016 and is headquartered in San Francisco, California.
Ochre Bio — Ochre Bio is developing therapies for the biggest liver health challenges.
Arpeggio Bio — We engineer medicine based not on a single target, but the biological network as a whole.

Paul Buchheit co-founded social network aggregator FriendFeed, along with three other former Google employees. He is also an investor in FriendFeed and participated in a $5 million Series A round in February 2008.He was the 23rd employee at Google, where he created Gmail and implemented many of its innovative features. He developed the originalprototype of Google AdSense, and was responsible for Google's famous "Don't be evil" motto in a meeting.

Investment focus

Software, Health Care, E-Commerce
Seed, Series A, Angel
United States, Canada, India

Portfolio highlights

SiPhox Health — SiPhox Health brings comprehensive, at-home blood testing to your door! Take control of your disease risk and increase your healthspan today with affordable, convenient at-home blood testing. No lab visits, no appointments, no waiting in line.
Character.ai — Chat with millions of AI Characters on the #1 AI chat app. Where will your next adventure take you?
Perplexity — Perplexity is a search engine platform that uses artificial intelligence to provide large language models and search engines. The company's platform enables the development of beneficial artificial general intelligence, as well as an open-source environment that is accessible to the public, allowing clients to develop skills and knowledge inartificial intelligence.

Before co-founding Flatiron, Zach was Co-Founder, President and COO of Invite Media, an advertising technology company based in NYC. Invite Media built the industry's first enterprise advertising platform for buying and optimizing online media in real-time. Invite Media was acquired by Google in 2010. Prior to Invite Media, Zach co-foundedEatNow.com which was privately acquired. An active angel investor, Zach has invested in over 30 technology startups throughout the country, including Bell Biosystems, Breakthrough.com, Care at Hand, DocPhin, Doctor Evidence, Genomera, Meddik, Oscar, and Predilytics. Zach studied economics and entrepreneurship at The Wharton School at the University of Pennsylvania.

Investment focus

Health Care, Software, Medical
Seed, Series A, Pre-Seed
United States, Israel, Colombia

Portfolio highlights

Iterative Scopes — Iterative Scopes provides gastroenterologists with machine learning-powered diagnostic tools that help them prevent colon cancer and improve patient outcomes
Overwatch Research — Generate accurate in vivo study data as a part of your efficient, connected R&D.
Nym — Nym Health leverages advanced AI for medical coding, revolutionizing accuracy and speed within revenue cycle management. Discover the difference.

Wei Guo, the founding partner of UpHonest Capital, is an active angel investor in Silicon Valley, focusing on early-stage cross-sector investments. He founded Wei Fund in 2015 and UpHonest Capital Fund I in 2016, invested in well-known companies such as Hims&Hers(NYSE: HIMS), Vicarious Surgical(NYSE: RBOT), Knightscope (NASDAQ: KSCP), Checkr,Lime, Boom, Rescale, Dialpad and more. Since 2015, he has invested in over 400 Silicon Valley startups, over 76 companies with valuations greater than 100 million USD, and 23 portfolio companies that have successfully exited.

Investment focus

Software, Artificial Intelligence, Health Care
Seed, Series A, Angel
United States, China, Canada

Portfolio highlights

Golden — Golden is a developer of a self-constructing knowledge database used to accelerate discovery and education. The company uses and leverages human effort by using machine intelligence to make the process of gathering and communicating knowledge simpler.It combines a powerful search across several entities with fine-grain alerts to stay on top ofchanges, and semi-automatic research assistance for gaps in knowledge that enable people in organizations to stay current, understand and leverage the latest trends in their industry.
Playbook — Playbook gives creators the opportunity to build and grow a subscription business. Fans get an all-access pass to a curated health and wellness content.
Crossing — Crossing Media is a live broadcast e-commerce service company that builds awareness, engagement, and sales through live-stream shopping.

Kevin Moore has 10 years experience as an angel/opportunity investor and operator. Prior to that, he has over 15 years of progressive technology i-banking, corp dev, and CFO experience at startups and $Bn corporates.

Investment focus

Software, Health Care, E-Commerce
Seed, Pre-Seed, Angel
United States, India, Canada

Portfolio highlights

Redbird — Redbird is an operating system that empowers data driven teams to easily create custom applications that automate advanced analytics work in minutes, without writing code.
SilkChart — SilkChart helps growth teams improve campaigns based on what users are doing in product - without relying on expensive data scientists. We do this through a no code analytics tool that combines marketing and product usage data to identify which channels, audiences, and content maximize revenue growth.
Augmend — Create documentation and an AI assistant from any video.

Anne Wojcicki is the Co-Founder and CEO of 23andMe. She previously worked at Passport Capital as a Healthcare Analyst. Anne Wojcicki attended Yale University.

Investment focus

Health Care, Medical, Biotechnology
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

World Labs — World Labs is an AI startup that can analyze visual data with comprehension akin to a person's, a substantial advancement above existing capacities.
Solace — Connect with expert patient advocates who can help you navigate the healthcare system and solve any medical problem, no matter what you need.
Endo Health — Reverse Your Diabetes With a Game

Jim Mellon is an international investor with interests in several industries. After leaving Oxford, where he studied PPE, (Philosophy, Politics and Economics) he worked in Asia and the United States for two fund management companies, GT and Thornton, before establishing his own business in 1991. His business operations include two components, alisted fund management company called Charlemagne Capital, and an Asian mining group, Regent Pacific.In addition, Mr. Mellon is Co-Chairman of West African Minerals Corporation and Regent Pacific Group. He is on the board of a number of public quoted companies, including Brazilian Gold Corporation, Charlemagne Capital Limited, Manx Financial Group, Plethora Solutions, Polo Resources, Port Erin Biophara Investments Limited, and the Speymill plc. He is the life tenant of a trust which owns the Burnbrae Group, which has substantial assets in the biotechnology, financial services, property, mining and leisure sectors. Mr. Mellon spends most of his time working on startup ideas and investing. His book, “Wake Up!” was published in 2005; his second book "10 Investments for the Ten Years Ahead" was published in 2008. In 2012, he co-wrote "Cracking the Code" which focuses on the biotechnology sector and how to profit from it. Mr. Mellon lives in the Isle of Man, Brussels and Ibiza and is an honorary fellow of Oriel College, Oxford.

Investment focus

Biotechnology, Food and Beverage, Health Care
Series A, Seed, Funding Round
United States, United Kingdom, Germany

Portfolio highlights

Voxia — Amy collects and analyzes information from all over the web and provides actionable insights about your leads, prospects and clients, all in one click.
Monaco Foundry — We are a team of Serial Entrepreneurs, former Senior Government Advisors and Fortune 500 Executives. A global venture accelerator that invests in early to mid-stage companies and their growth through a unique sweat equity model.
The Duppy Share — The Duppy Share Caribbean Rum is the best rum for cocktails, mixed drinks and rum gifts. Try all our rum recipes, from rum and ginger to dark rum punch.

Evan Cheng Co-founder & CEO at Mysten Labs. He attended Syracuse University.

Investment focus

Software, Artificial Intelligence, Biotechnology
Seed, Pre-Seed, Funding Round
United States, United Kingdom, Australia

Portfolio highlights

Jarsy — Jarsy Inc offers a platform for global investment opportunities using stablecoins.
PIN AI — PIN AI democratizes personal on-device intelligence for everyone; transform your digital footprints into your Personal Executive Assistant.
Verida — The Verida Wallet is a mobile application that allows you to manage your decentralized identity and personal data. It provides a user-friendly interface for interacting with applications built on the Verida network.

Brian Armstrong is the CEO and Co-Founder of Coinbase. He previously worked at Airbnb.com as a Technical Product Manager. Brian Armstrong attended Rice University.

Investment focus

Payments, Financial Services, Biotechnology
Seed, Series A, Series B
United States, Brazil

Portfolio highlights

NewLimit — NewLimit is extending human healthspan by unlocking regenerative potential.
Stark Bank — Stark Bank is a smart bank account that aids a technological advancement of a company. It is a financial technology that allows companies to expand their operations by allowing them to make extra transfers, payments, and charges.
Orchid — Orchid is a reproductive technology startup that is capable of detecting rare genetic disorders. Orchid’s preconception system analyzes both partners’ genomes and assesses genetic predispositions to common diseases, including heart disease, stroke, schizophrenia, Alzheimer’s disease, breast cancer, and diabetes. Orchid results are developed withworld-class experts in reproductive medicine and genetics to give its clients the most accurate results.Orchid offers a “Couple Report” that utilizes an at-home saliva test to analyze each person’s genomes to detect the probability of genetic risks, then models how their DNA together will combine in a future child. If elevated risk is detected, Orchid provides insights to help couples monitor biomarkers, adapt their diet or elect for procedures, such as in vitro fertilization. It was founded by Noor Siddiqui in 2019 and is headquartered in San Francisco, California.

Erik Peterson is the Founder at DormTrader.

Investment focus

Software, Biotechnology, SaaS
Seed, Equity Crowdfunding, Series A
United States, Canada, Algeria

Portfolio highlights

Hideout — Hideout makes high-quality food that is available for delivery. Danielle Sobel established the company in Los Angeles, California.
Abalone Bio — Our Functional Antibody Selection Technology platform (FAST) taps into the potential of the body's biological activities, expanding the reach of antibody drugs.
Altay Therapeutics — Pioneering the first oral drug for FSHD and advancing cancer treatment solutions.

Chris Gibson is the Co-Founder and CEO of Recursion (Recursion Pharmaceuticals). He previously worked at Cure HHT as a Member Board of Directors. Chris Gibson attended the University of Utah.

Investment focus

Biotechnology, Health Care, Life Science
Series A, Seed
United States, France, Switzerland

Portfolio highlights

Amenities Health — Amenities is the healthcare industry's leading Digital Front Door and patient loyalty platform. We help healthcare providers to acquire new patients and upgrade them to members. Our all-in-one patient app works with most modern EMRs to: 1) register new users into a full EMR account in <30 seconds with full identity verification and noduplicates, 2) help those patients find care options and book appointments with simple, conversion-optimized workflows, 3) seamlessly integrates key patient portal and 3rd party functions (i.e., video visits, secure messaging, test results, and billing), and 4) upgrade patients to members with custom experiences and services offerings (i.e., for Medicare Advantage, concierge memberships, direct-to-employer, or direct primary care patients)
Cradle — Using robust prediction algorithms and AI design recommendations, Cradle assists biologists in rapidly designing better proteins. Cradle gives you complete ownership of the intellectual property while maintaining the privacy and security of your sequences and data.
Leash Biosciences — We're transforming drug design with a rich dataset built by screening millions of compounds against thousands of protein to generate billions of data points, ideal for training advanced machine learning models.

Daniel Curran is the Founder and CEO at CustEx.com.

Investment focus

E-Commerce, Software, Internet
Seed, Series A, Series B
United States, Canada, Brazil

Portfolio highlights

RentoMojo — RentoMojo is an online furniture rental platform that was incorporated in November 2014.It currently operates in Bangalore, Pune, Mumbai, Hyderabad, Chennai, Delhi, Gurgaon and Noida.RentoMojo was founded by Geetansh Bamania, an ex-IITM, in November 2014 in India. Like many other young working professionals, he was living in rented apartments,working long hours and found it inconvenient to equip the house with furniture when he moved. RentoMojo was developed to provide an alternative to buying and selling furniture in rental properties.
Shred Video — Shred Video, a new startup launching out of Y Combinator, allows users to take footage from their iPhone, GoPro or drone and simply match it with a song from the user’s iTunes library. That’s all. Shred Video does the rest of the work.Taking into account the acceleration of the camera itself, Shred Video can pin-point the moments of action forsurfers, snowboarders, skaters and other acceleration-based sports to highlight all of the coolest clips in your footage. And beyond that, Shred Video matches those epic moments with the beat-drop of the song.
GC Plus — Find Your Next Home Service Expert With Ease

Fred Ehrsam is the Co-Founder of Paradigm.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Series C
United States, Canada, Israel

Portfolio highlights

Swift Solar — Swift Solar is a US solar technology company building high-performance perovskite tandem products. Our mission is to unlock the full potential of solar energy.
Chai Discovery — Building frontier artificial intelligence to predict and reprogram the interactions between biochemical molecules.
Arcadia Medicine — Arcadia Medicine is a biotechnology company that creates psychedelic medicine to treat mental health issues.

Elad Gil is the Co-Founder of Color Genomics. He previously worked at Twitter as a Vice President. Elad Gil attended the Massachusetts Institute of Technology.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, United Kingdom, Israel

Portfolio highlights

Ashby — Ashby is a developer of recruitment software used for high-growth companies. It develops usable, enterprise-grade employment software that enables company leaders, recruiters, and hiring managers to run their hiring process significantly better. It was founded in 2018 and is based in San Francisco, California.
Harvey — Harvey is an artificial intelligence technology service provider.
Cognition — Cognition is an applied artificial intelligence lab that focuses on reasoning and code.

Balaji S. Srinivasan is the Co-Founder and Board Member of Coin Center. He was the CTO of Coinbase and cofounder of Counsyl, Earn, Teleport, and Coin Center. He was previously CEO at Earn.com, which was recently sold to Coinbase. Prior to taking the CEO role at Earn.com, Dr. Srinivasan was a General Partner at Andreessen Horowitz. Prior to joininga16z, he was the co-founder and CTO of Founders Fund-backed Counsyl, where he won the Wall Street Journal Innovation Award for Medicine and was named to the MIT TR35. Dr. Srinivasan holds a BS, MS, and PhD in Electrical Engineering and an MS in Chemical Engineering from Stanford University. He also teaches the occasional class at Stanford, including an online MOOC in 2013 which reached 250,000+ students worldwide.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Pre-Seed, Series A
United States, India, Singapore

Portfolio highlights

Blitz Electric Mobility — Blitz provides electric vehicles and fleet management software to food and beverage delivery, courier, and logistics companies.
Paradigm — The AI-powered way to do spreadsheet work. Set up, edit, populate, and analyze sheets with assistant. Enrich empty cells with data from trusted sources.
Inversion — Inversion is a technology-first investment company that acquires and transforms legacy businesses with blockchain technology.

Mark Cuban is the founder of Fireside, Chairman and Founding Partner of AXS TV, and the Owner of Dallas Mavericks. He previously worked at Broadcast.com as a Co-Founder. Mark Cuban attended the Indiana University Bloomington.

Investment focus

Software, Artificial Intelligence, Blockchain
Seed, Series A, Funding Round
United States, United Kingdom, Singapore

Portfolio highlights

Yendo — Our mission is to provide everyone with the most accessible, most affordable, and most transparent credit by leveraging their vehicles.
TransCrypts — We all have that file box where we throw all our important documents. Our goal at TransCrypts is to make that box digital and have all the documents secured through the blockchain. We currently offer industry leading privacy and security standards on our file storage and sharing platform and have solutions for individuals all the way to enterprises.
FORT Robotics — FORT Robotics enables OEMs & end users to build and operate smart machines safely and securely, while maximizing productivity and reducing risks.

Darian Shirazi is the Managing Partner of Gradient.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, Germany, Canada

Portfolio highlights

Valdera — Valdera is the sourcing and procurement platform that makes it easy to buy or sell chemicals, ingredients, and raw materials. We partner with segment leaders, ranging from the world's largest CPG manufacturers to household names in the beauty industry.
Twenty (YC S23) — Building a better Salesforce, powered by the Open Source community.
Twenty — Twenty builds the modern salesforce, powered by the open source community.

Peter Thiel Is the Managing Partner of The Founders Fund. He previously worked at Stanford Law School as a Visitor. Peter Thiel attended Stanford University.

Investment focus

Software, Financial Services, FinTech
Series A, Seed, Series B
United States, Germany, Canada

Portfolio highlights

STARK — STARK is a technology-driven defence company with the mission to deliver the systems that Europe and NATO need now.
Quantum Systems — Our vision is to become the global leader in providing aerial data for decision making by the use of our drones.
Kriya Therapeutics — Kriya is a biopharmaceutical company developing gene therapy to address common diseases that impact millions of people worldwide. Learn more.

Nat Turner is based out of New York, New York, and is the CEO and Chairman of Collectors. Nat previously worked at OneOncology as a board member. Nat Turner attended the Wharton School of the University of Pennsylvania.

Investment focus

Health Care, Software, Medical
Seed, Series A, Series B
United States, China, Colombia

Portfolio highlights

Connie Health — At Connie Health, our Medicare advisors help older Americans find the right Medicare plan - all at no cost to you.
Memora Health — Meet patients where they are. Digitize your clinical workflows to modernize and simplify patient care.
Iterative Scopes — Iterative Scopes provides gastroenterologists with machine learning-powered diagnostic tools that help them prevent colon cancer and improve patient outcomes

Todd Corenson - Founder @ Enlon

Investment focus

Biotechnology, FinTech, SaaS
Seed, Pre-Seed, Convertible Note
United States

Portfolio highlights

Solugen — Solugen's mission is to decarbonize the chemicals industry. Solugen combines synthetic biology with metal catalysis to make carbon negative chemicals at scale.Solugen's patented approach takes advantage of bio-inspired reactions to use plant material as a low-cost feedstock to produce novel products cost-competitive with thecompetition.
HelixNano — Helix Nanotechnologies uses artificial intelligence to help cure genetic diseases. HelixNano is a Y Combinator and venture backed biotech startup. At HelixNano, we have spent the last two years developing cancer vaccines. Now we are adapting our synthetic biology arsenal to take on COVID-19. We’re moving fast but thinking long-term. We’re alreadytesting COVID-19 vaccine candidates designed to be precise and safe. Our next goal is to create a vaccine that protects everyone not only from this virus, but all future coronaviruses.
iMicrobes — We are a synthetic biology company on the mission to work with the world's largest companies to use new raw materials and recycle waste for chemical production, polymers, agriculture, and space exploration.

David is Professor in the Department of Pathology, Brigham and Women’s Hospital and Wyss Institute for Biologically Inspired Engineering, and is a Howard Hughes Medical Institute Professor. David is the Scientific Founder of Illumina Inc. and Quanterix Corp and has co-founded several other life sciences startups. David has published over 300peer-reviewed papers and has over 75 issued US patents. He has received numerous national and international awards and honors for his fundamental and applied work in the field of optical microwell arrays and single molecules including the American Chemical Society Kathryn C. Hach Award for Entrepreneurial Success, Ralph Adams Award in Bioanalytical Chemistry, the American Chemical Society Gustavus John Esselen Award, Analytical Chemistry Spectrochemical Analysis Award, the Pittsburgh Analytical Chemistry Award, and the ACS National Award for Creative Invention. He is a member of the National Academy of Engineering, the National Academy of Medicine, a Fellow of the American Academy of Arts and Sciences, a Fellow of the American Institute for Medical and Biological Engineering, and a Fellow of the National Academy of Inventors. He received a BS in Chemistry from the University of Michigan and a PhD in Chemical Biology from SUNY at Stony Brook, and did postdoctoral studies at MIT.

Investment focus

Biotechnology, Genetics, Life Science
Seed, Series A, Series B
United States

Portfolio highlights

Vizgen — The next generation of genomics, expanding the impact of spatial context and demonstrating the potential of in situ single-cell spatial genomics.
Stoicheia — NAGASPIN99 adalah link situs slot gacor hari ini yang menawarkan bonus berlimpah khusus pemain baru. Klik Daftar dan raih kemenangan besar bersama naga api sekarang juga.
Torus Biosystems — Torus Biosystems offers an apparatus for DNA testing for scientific and medical research purposes in the fields of consumer products, food for human beings or animals, hygienic and beauty care for human beings or animals, agriculture, horticulture, and forestry. The company was founded in 2019 and is headquartered in Cambridge, Massachusetts.

David is a Partner of Amplify Partners and co-founder of Chartio.com.Before joining Amplify Partners, David spent time as both a venture-backed entrepreneur and an early-stage investor. He began his career in technology as the co-founder and CEO of Chartio.com, a pioneering provider of cloud-based data visualization and analytics. He wassubsequently part of the founding team at Patients Know Best, one of the world’s leading cloud-based personal health record companies. David has been a prolific investor and advisor to entrepreneurs. He has personally invested in more than 50 early-stage companies, including Zymergen, Skycatch, Caribou Biosciences, Rigetti Computing, Casetext, Ginkgo Bioworks, Function of Beauty, Cruise Automation, and Bugcrowd. In addition, he currently serves on the advisory council of Bayes Impact, a nonprofit organization that deploys data science to solve important social challenges.He attended Brown University.

Investment focus

Software, Artificial Intelligence, Enterprise Software
Seed, Series A, Angel
United States

Portfolio highlights

Airtable — Airtable is the AI-native platform for building trusted AI apps to accelerate business operations and deploy embedded AI agents at enterprise scale.
Astranis — Four billion people still have no internet access. Astranis is here to change that. We're making small satellites for geostationary orbit, recently signed a contract to triple the satellite internet capacity of Alaska, and raised our Series A from Andreessen Horowitz.
Skycatch — Industry-Leading Drone Automation and AI-Driven Data Analysis Platform Transforming Global Industries

Brad Flora is a Visiting Partner at Y Combinator. He is a former Co-Founder and CEO of Perfect Audience. Mr. Flora received a BA from Princeton University in English and an MS in Journalism from Northwestern.

Investment focus

Software, Artificial Intelligence, SaaS
Pre-Seed, Seed, Series A
United States, United Kingdom, Mexico

Portfolio highlights

SWAP — Swap empowers companies to transform their financial operation with an innovative approach, technology, and business model. SWAP’s APIs offer clients end-to-end, white-label, financial solutions. Connected to them, its clients are able to develop complete financial ecosystems including pre-paid cards, digital wallets, financial services and furthermonetize their platform while expanding their core experience. It removes barriers and generates new business lines for companies, effectively creating internal fintech.
Truewind — Using AI to power bookkeeping & finance means less errors, more transparency, and faster monthly close
Ellipsis — Automated code reviews and bug fixes. Software engineers are more productive with Ellipsis, a developer tool that catches bugs, answers questions, and generates working, tested code.

Daren was the Founder and CEO of InboxDollars, an online marketing company that connects consumers and advertisers in a way that benefits both. He founded the company as a Freshman in college in 2000 and bootstrapped the company to more than $25 million in annual revenues. InboxDollars was acquired by Prodege in 2019. Daren is active in the MNstart-up community as an investor, advisor and mentor.

Investment focus

Software, Health Care, E-Commerce
Seed, Series A, Funding Round
United States

Portfolio highlights

Delfina — Intelligent pregnancy care for healthier moms and babies.
Coldcart — Coldcart is a technology platform which orchestrates, optimizes and scales frozen and refrigerated parcel logistics for leading D2C and B2B companies - unlocking unprecedented new efficiencies in perishable parcel logistics.
Evecxia Therapeutics — Evecxia Therapeutics is dedicated to realizing the therapeutic potential of 5-hydroxytryptophan (5-HTP) for the treatment of mental illness.

Dr. Ling Wong is Founder and General Partner of Highbury Group and Sea Lane Ventures. She also serves as Senior Advisor to Lightspeed Venture Partners. Highbury Group was founded on the principle to be a true partner and champion to entrepreneurs, using science and technology to build companies that fundamentally transform the world for thebetterment of humanity today, and in the future.Dr. Wong draws from her unique background and experience as a scientist, entrepreneur, and investor to support and bring to market companies that exist at the intersection between health and technology. “I love to partner with mission-oriented founders working on transformational ideas that can have a positive, lasting impact on society – and do so by leveraging technology and science in a financially sustainable manner,” said Dr. Wong.Prior to Highbury, she served at the Gates Foundation where she helped to establish a $1.5B global investment portfolio and created a $200M early stage program to support early stage entrepreneurs in more than 60 countries.As a health and technology investor, Dr. Wong has been involved in some of the market’s most significant investments and exits. She has partnered with over fifteen $1B+ companies, including: Devoted Health, Orca Bio, Collective Health, Color, Apeel, Shape, Stripe, Offer Up, Rappi, Branch Metrics, Notion, Modern Animal, Wheel and Satellite Bio. Notable exits include: Anacor Pharmaceuticals (acquired by Pfizer for $5.2B), Genocea Biosciences (NASDAQ: GNCA), Visterra (acquired for $430M), Slack (NYSE: WORK), Guardant Health (NASDAQ: GH), and recently Singular Genomics (NASDAQ: OMIC).Dr. Wong holds a PhD from Harvard in Engineering Sciences, a BSc in Chemical Engineering and BSc in Biology from MIT. During her time at Harvard, she created the world’s first inhaled TB vaccine. Her scientific training has shaped how she assesses financial opportunities, both to create value and to benefit human health. Dr. Wong has always been passionate about seeking entrepreneurs and partners that are looking to disrupt the status quo in science and technology for the betterment of society.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Colombia

Portfolio highlights

Notion — Build custom agents, search across all your apps, and automate busywork. The AI workspace where teams get more done, faster.
Satellite Bio — Satellite Bio specializes in cell therapy, regenerative medicine, synthetic biology, cell biology, and tissue engineering. It focuses on the development and implementation of proprietary, off-the-shelf, implantable satellite organs as living therapeutic solutions that can transform the lives of millions of patients who suffer from serious diseases.
Devoted Health — Devoted Health is a new healthcare company serving seniors. Aiming to launch Medicare Advantage plans in 2019, their mission is to build a healthcare solution good enough for Mom. They will be devoted to the health and wellness of their members by helping them navigate the health care system with personal guides, by utilizing world-class technologyto enable a simplified experience, and by partnering with top providers for better health outcomes.

Brenton Saunders is the current Chief Executive Officer of Bausch & Lomb. He previously worked at The Allergan Foundation as a Chairman. Brenton Saunders attended Temple University’s Fox School of Business.

Investment focus

Health Care, Medical, Biotechnology
Seed, Series A, Series B
United States

Portfolio highlights

Wondermind — Welcome to Wondermind, your home for approachable, expert-backed mental health content you can actually use.
Nucleus — Nucleus provides genetic analysis of greater breadth, depth, and beauty. Users can upload their genetic information obtained through an established company. The proprietary algorithms will calculate polygenic risk scores and measure disease risk based on analysis of genetic variants and display them in a user-friendly platform.
Lipidio Pharmaceuticals — A Unique Approach to Treating Obesity Precision Targeting of the Skin Exploiting the skin as an endocrine organ Historically regarded as a protective barrier organ, the skin is now recognized as an active endocrine organ capable of synthesizing, and secreting diverse hormones and signaling

Bill Gates is the Co-chair of Bill and Melinda Gates Foundation. He attended Harvard University.

Investment focus

Biotechnology, Energy, Manufacturing
Series A, Series B, Series C
United States, Canada, Israel

Portfolio highlights

TerraPower — Leading innovations in nuclear applications for reactor and storage technology, while advancing methods to transform the fight against cancer.
Inflection AI — Inflection AI is pioneering the future with human-centered, emotionally intelligent AI that transforms interactions from transactional to reltational, creating enduring value for individuals and enterprises alike.
Nimbus Therapeutics — Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company. Nimbus Therapeutics is a biotechnology company headquartered in Cambridge, Mass., that is pioneering a new computational technology-driven paradigm to rapidly advance a diverse pipeline of novel small molecule product candidates into clinicaldevelopment. We are designing highly selective and potent medicines to disrupt known drivers of serious diseases, including metabolic disease, cancer and immune-inflammatory disorders.

Eric Kwan - Co-Founder & Managing Partner @ Locus Ventures

Investment focus

Software, FinTech, E-Commerce
Seed, Pre-Seed, Funding Round
United States, India, Canada

Portfolio highlights

Treinta — Treinta is a digital ledger app for Latin American microbusinesses. Through Treinta, users can easily record transactions by assigning products from their inventory and see how their business metrics evolve in real time. The app helps owners save up to 30 minutes a day in bookkeeping related tasks and improve efficiency by over 30%. Out of the 50million microbusinesses in LATAM, today 90% still track their sales and expenses by using pen and paper.
Ferveret — Ferveret develops liquid cooling technology for data centers and other infrastructure. Our company is backed by Y Combinator and MIT Media Lab's E14.
Kriya AI is now Kalendar AI — Kalendar AI books new revenue on autopilot

Max Levchin is the Founder and CEO of Affirm. He previously worked at the Consumer Financial Protection Bureau as an Advisory Board Member. Max Levchin attended the University of Illinois Urbana-Champaign.

Investment focus

FinTech, Financial Services, Software
Series A, Seed, Series B
United States, United Kingdom, India

Portfolio highlights

Bland AI — Transform your enterprise communication with Bland AI. Automate inbound and outbound phone calls using AI that sounds human. Perfect for sales, customer support, and operations with customizable voices and seamless integrations.
CoPilot — CoPilot is pioneering Assisted Commerce for big-ticket purchases – starting with cars. You are the one spending the money - shouldn't you have an expert on your side? We founded CoPilot to make that a reality. For the average car buyer, who is not a car expert or enthusiast, car shopping can be a time consuming, frustrating process that leavespeople feeling alone and disadvantaged. CoPilot is changing this dynamic. Like a trusted friend who is knowledgeable about cars, knows where to look and what to buy, CoPilot provides car shoppers with an expert partner who empowers them to discover the perfect car at the best possible price with ease and confidence.
Black Ore Technologies — Black Ore's Tax Autopilot is the first AI tax platform for CPAs, offering complete 1040 tax preparation automation to tax professionals, so they can focus on growing their firm.

Bill Gates is the Co-chair of Bill and Melinda Gates Foundation. He attended Harvard University.

Investment focus

Energy, Biotechnology, Manufacturing
Series C, Series A, Series B
United States, Canada, Israel

Portfolio highlights

Mainspring Energy — Flexible onsite generation for data centers, utility, industrial & enterprise applications. Fuel-flexible, fast to deploy, high-efficiency, low NOx power.
Echodyne — Echodyne develops and manufactures meta-materials-based radar technologies. The company combines the patented technology of metamaterials with powerful software to create a radar sensor with unprecedented performance at commercial price points. Echodyne's patented technology and powerful software create a high-performance radar platform thatproduces security and machine autonomy solutions for government, defense, and industry.Echodyne was founded in 2014 and is headquartered in Kirkland, Washington.
TerraPower — Leading innovations in nuclear applications for reactor and storage technology, while advancing methods to transform the fight against cancer.

Esther Dyson - Founder @ Way to Wellville

Investment focus

Health Care, Software, Medical
Seed, Series A, Funding Round
United States, Canada, Russian Federation

Portfolio highlights

Ezra AI — Ezra provides full-body MRI screening for potential early cancer and abnormalities in up to 13 organs. Book a scan today.
NextSense — Introducing NextSense Smartbuds: EEG-powered earbuds that go beyond sleep tracking. Backed by science, Smartbuds provide real-time insights to help you achieve deeper, more restorative sleep. Comfortable, intuitive, and easy to use, Smartbuds empower you to wake up your best self.
Openwater — OPENWATER - THE FUTURE OF NEURAL DIAGNOSTICS IN THE PALM OF YOUR HAND.

Jack Abraham is based out of Florida and is the Chairman and Co-Founder of Indomo. Jack previously worked at TalkIQ as a Co-Founder and Investor. Jack Abraham attended The Wharton School.

Investment focus

Health Care, Software, Financial Services
Seed, Series A, Series B
United States, France, Hong Kong

Portfolio highlights

Iron Fish — Enable the free flow of assets through accessible and private cryptocurrency.
NUE Life Health — NUE Life aims to improve mental wellness by enhancing brain function, performance, and longevity through evidence based and scientifically proven mental health treatments and products.
ANA Therapeutics — ANA Therapeutics is a developer of a novel coronavirus vaccine intended to save human lives. It is developing therapeutics to solve the coronavirus pandemic using Niclosamide that enables medical practitioners to treat patients suffering from COVID-19. It was founded in 2020 and is headquartered in Foster City, California.

Cory Levy is the Founder Advisor of Humaning.

Investment focus

Artificial Intelligence, Software, Information Technology
Pre-Seed, Seed, Series A
United States, Canada, India

Portfolio highlights

Brellium — Clinical teams use Brellium to audit every patient visit against their clinical and payor requirements.
Omen AI — Harness the power of Ai and proprietary sensing to prevent equipment failures.
Hidden Studios — Hidden Studios develops and advertises Fortnite Creative games, with 100M+ plays monthly. The company collaborated with prominent brands and creators, including Skydance, Snoop Dogg, and CaseOh, to deliver engaging gaming experiences. Hidden Studios maintains an active presence on YouTube, sharing content related to their Fortnite Creativeendeavors.

Timothy Springer is an internationally recognized leader in structural biology and immunology. With over 500 peer-reviewed publications that have received over 90,000 citations, he is one of the most highly cited scientists in any field. Timothy Springer received his Ph.D. from Harvard University in 1976, and subsequent post-doctoral training withDr. Cesar Milstein in Cambridge, UK. Timothy Springer has been elected to the National Academy of Sciences and to the American Academy of Arts and Sciences. Among numerous awards and honors, Timothy Springer is a recipient of the Royal Society of Medicine Medal, the William B. Coley Medal from the Cancer Research Institute, and the Crafoord Prize from the Swedish Academy of Sciences. Timothy Springer's research laid the foundation for a new class of pharmaceuticals, the selective adhesion molecule inhibitors, which include the approved drugs, alefacept, efalizumab, and natalizumab. Timothy Springer was the Founder of LeukoSite, a biotechnology company acquired by Millennium Pharmaceuticals in 1999. LeukoSite developed therapeutics for inflammatory, autoimmune, and cancer applications, including FDA-approved Campath™.

Investment focus

Biotechnology, Medical, Health Care
Series B, Series A, Seed
United States, Canada

Portfolio highlights

Prenuvo — Changing the medical paradigm from sick care to proactive healthcare
Seismic Therapeutic — Seismic Therapeutic is a biotechnology company integrating machine learning across the entire biologics discovery process to accelerate immunology drug development. Using its IMPACT™ platform, the company is addressing the central challenges of biologics discovery and development by fully integrating machine learning with the key elements ofbiologics drug discovery – structural biology, protein engineering, and translational immunology – to create optimized therapies on an accelerated path to patients. Seismic Therapeutic has an emerging pipeline of novel biologics to address adaptive immune system dysregulation to treat autoimmune diseases.
Tectonic Therapeutic — Tectonic is a biotechnology company focused on the discovery and development of proteins and antibodies that modulate the activity of G-Protein Coupled Receptors.

John D'Orazio is the Founder and Managing Partner of Proton Enterprises. He previously worked at SlideMoor as an Executive Partner. John D'Orazio attended Xavier University.

Investment focus

Biotechnology, Medical, Health Care
Seed, Funding Round, Equity Crowdfunding
United States

Portfolio highlights

RenovoDerm — A medical device company building a line of wound care products that provide a structure for tissue growth and promote faster healing of wounds—while reducing scar tissue. Funding prior to formation: $1.6 million.
Vascular Genesis — A medical device company laying the foundation for vascular conduit replacement with its line of cell-free, synthetic scaffold products -- with self-healing capabilities that lower the risk of rejection, infection, and stenosis. Funding prior to formation: $2.5 million.
Atreon Orthopedics — A medical device company building a line of orthopedic products that provide a structure for tissue growth and healing of sports medicine injuries including tendon ruptures/tears.

Avichal is Managing Partner at Electric Capital. He is a serial entrepreneur and technology executive. Avichal sold two companies and was most recently Director of Product at Facebook, which acquired his company Spool in 2012. He previously worked at Google on search ranking and ads ranking, is part-time at YCombinator, and an active angelinvestor.Avichal's firm, Electric Capital, focuses on cryptocurrencies that are rooted in technological utility. Electric performs deep technological diligence, such as compiling code, profiling nodes, and analyzing blockchains with in-house software. The founders of Electric have started and sold five companies, have been investing in cryptocurrencies since 2013, and are investors in Anchor, Bitwise, Chia, Coda, dYdX, Dfinity, Oasis, Thunder and many other crypto projects.

Investment focus

Software, Blockchain, Internet
Seed, Series A, Funding Round
United States, Canada, Mexico

Portfolio highlights

Key — Unlock new networking and career opportunities with Key, the leading AI-powered professional networking platform. Build and manage communities, host and join exclusive events, and create meaningful connections to supercharge your growth all in one place.
Matic — The world's most advanced floor cleaner. Your home's best helper.
Bluenote Health — Accelerate innovation with AI built for and trusted by leading life sciences companies.

Bradley Horowitz is an Advisor and Vice President of Product Management at Google. Most recently he helped create Area 120, Google's incubator for internally-sourced innovation. He's led a large number of products, programs and initiatives at Google - including Google for Startups, Google Photos, Gmail, Google Voice, blogger, and GoogleNews.Before joining Google in February 2008, Horowitz was Yahoo's vice president of Advanced Development where he drove the acquisitions of Flickr and MyBlogLog, launched the Brickhouse incubator and developed new products like Yahoo! Pipes. Additionally, he was responsible for the company's initiative to open up its platform which included overseeing the Yahoo Developer Network (YDN).Previously, he was co-founder and CTO of Virage, where he oversaw the technical direction of the company from its founding through its IPO and eventual acquisition by Autonomy.Horowitz was a PhD candidate at the MIT Media Lab. While at the Media Lab, he worked on a number of topics related to computer vision, graphics and image processing, which resulted in a patented new technique for the recovery of structure, motion and camera parameters from video sequences.Horowitz holds an MS in Media Science from MIT and a BS in Computer Science from the University of Michigan.

Investment focus

Software, Information Technology, Health Care
Seed, Series A, Series B
United States, United Kingdom, Germany

Portfolio highlights

Key AI — Unlock new networking and career opportunities with Key, the leading AI-powered professional networking platform. Build and manage communities, host and join exclusive events, and create meaningful connections to supercharge your growth all in one place.
Opal — Making it better at capturing incredible low-light video. Even in dimly lit room, you’ll get a level of detail and color that wasn’t possible before.The Opal C1 comes with MicMesh™, an array of beamforming microphones that find and focus on the sound of your voice. And with intelligent noise cancellation, every ding, drop and dog bark is filteredout to get an audio experience that clearly speaks for itself.
Audioshake — AudioShake makes audio interactive, customizable, and accessible by using AI to separate sound recordings into their component parts and stems.

Patrick Hsu

Investment focus

Biotechnology, Health Care, Medical
Seed, Series B
United States

Portfolio highlights

Vial — Next-generation pharma company advancing a pipeline of potentially best-in-class biologics and RNA therapeutics across areas of unmet need.
Nucleus — Nucleus provides genetic analysis of greater breadth, depth, and beauty. Users can upload their genetic information obtained through an established company. The proprietary algorithms will calculate polygenic risk scores and measure disease risk based on analysis of genetic variants and display them in a user-friendly platform.

John Ballantyne is a founder of Agathos Biologics. He co-founded Aldevron with Michael Chambers in 1998 and has been the Chief Scientific Officer since its establishment. His innovative work at Aldevron includes creation of the GMP Source product line and collaborative research with military scientists in the development of vaccine andpassive-based countermeasures to lethal and potentially weaponized viral hemorrhagic threats such as Ebola, Marburg and some hantavirus family members. He leads the research and development team at Aldevron which develops new methods and products through internal programs, collaborations, and technology licensing. John sees the advances in biotechnology providing opportunities for Agathos to enable ethical pharmaceutical development that will benefit patients, employees, and society. Ballantyne received undergraduate degrees in Pharmacy from the Central Institute of Technology and the University of Otago in New Zealand. After beginning graduate school in New Zealand he transferred to the United States in 1994 and completed his Ph.D. in Pharmaceutical Sciences at North Dakota State University.

Investment focus

Genetics, Health Care, Life Science
Series A
United States

Portfolio highlights

Elegen — Elegen is powering the bioeconomy with high-accuracy DNA synthesis that delivers industry-leading speed, length, and quality.
VerImmune — Located in Baltimore, Maryland, VerImmune is an Immuno-Oncology company developing a first-in-class cancer therapy known as Anti-tumor Immune Redirection. This strategy utilizes a proprietary tumor-specific, tumor type agnostic, virus-inspired platform termed Anti-tumor Immune Redirection Virus-inspired Particles (AIR-ViPs) that redirectspre-existing pathogenic or childhood vaccine immune memory towards tumors.
Cytonus Therapeutics — Cytonus Therapeutics is a biotech company that develops a therapeutic platform designed to treat immune-related disorders. The Cargocyte platform at Cytonus has diverse applications as it can be engineered to target specific tissues and can deliver strategic therapeutic payloads.

Erik Moore is the Founder and Managing Director of Base Ventures, an early-stage tech venture fund. He was one of the first investors in Zappos (sold for 1.2B to Amazon) and an early investor in Plangrid, sold to Autodesk for $875mm. Prior to Base Ventures, Erik spent 15 years in investment banking at Merrill Lynch. He recently joined the boardof the Common Ground Foundation, founded by Grammy, Oscar and Emmy award winning artist, Common, and he currently serves as a board member for P.A.C.E, a private philanthropic group. He was recognized as #10 on a list of the top 25 most influential blacks in tech by Business Insider (John Thompson, Chairman of Microsoft was ranked #1). He mentors and advises several known professional athletes. Erik earned his B.A. from Dartmouth College, an MA in French from the University of Pennsylvania, and his MBA from The Wharton School of Business.

Investment focus

Mobile, Software, E-Commerce
Seed, Series A, Funding Round
United States, Latvia

Portfolio highlights

Swapbox — Swapbox is an easy and convenient delivery system that enables people to send and receive packages using a Swapbox kiosk. The kiosks, which are completely automated, are situated in convenient locations including grocery stores, petrol stations and coffee shops, meaning that customers do not need to rush to the post office by 3pm to send theirpackages. Customers simply place their item/s in the Swapbox kiosk and input their details using the touchscreen. The recipient then collects the package from a local Swapbox using the code they received through text or email. Swapbox sets itself apart by focusing on consumer satisfaction, experience and convenience.Swapbox is currently available in San Francisco and Santa Clara.
Pigeonly — Pigeonly offers reliable inmate communication services, including phone calls, photos, and mail. Stay connected to your loved ones in prison easily and affordably.
Share Practice — Share Practice helps doctors identify and understand the most effective clinical treatments based on the success of other doctors.

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