Top 50 Life Science Angel Investors in United States (August 2026)

Portfolio highlights

• Seezo — Security design reviews for every feature your company builds. Someday, we will be more active on Twitter
• Neurable — Neurable is a neurotechnology company specializing in developing AI-powered tools for brain signal translation and brain-computer interface technology. Utilizing patented signal processing, developed through research across labs and institutions, and advanced by a scientific and expert product team, its platform enables high-performancebrain-computer interface in everyday devices.
• Normal Computing — Normal Computing was founded by former members of the Google Brain Team, Palantir, and X who unlocked AI for some of the largest-scale and most mission-critical production systems, and the industry leading ML frameworks for Probabilistic and Quantum AI.

Portfolio highlights

• Replit — Replit is a simple yet powerful online IDE, Editor, Compiler, Interpreter, and REPL. Code, compile, run, and host in 50+ programming languages.
• Revalia Bio — Revalia Bio develops curative drugs for chronic organ-centered disease.
• Future Fields — Future Fields Cellular Agriculture: Serum-Free Growth Media Supplements and Recombinant Proteins - Optimized for the Future of Food.

Portfolio highlights

• Zanskar — Zanskar Geothermal & Minerals uses custom AI tools and geoscience models to analyze vast amounts of data and pinpoint untapped geothermal hotspots.
• Play Health — Delivering data & AI-driven (peri)menopause care software to improve outcomes today, developing precision medicine infrastructure for tomorrow.
• Dunia Innovation — Catalysing the energy transition.

Portfolio highlights

• Sorare — Global Fantasy Football. Collect limited edition digital collectibles, Manage your team and earn prizes!
• Hoth Intelligence — Hoth Intelligence home page. Space age surgical technology brought down to earth.
• Floating Point Group — Floating Point Group is a trading platform provider offering innovative, industry-leading trade execution and settlement

Portfolio highlights

• SilkChart — SilkChart helps growth teams improve campaigns based on what users are doing in product - without relying on expensive data scientists. We do this through a no code analytics tool that combines marketing and product usage data to identify which channels, audiences, and content maximize revenue growth.
• Trace — Trace is an orchestration engine that breaks down existing workflows, assigns repetitive tasks to AI agents and routes the rest to the right people.
• Augmend — Create documentation and an AI assistant from any video.

Portfolio highlights

• Lamin — Open data platform for traceable multimodal AI. Query, trace, and govern data with a lineage-native lakehouse for files, tables, arrays, ontologies, and notes.
• Ridge AI — Ridge AI makes it fast and easy for SaaS companies to prove value inside their product.
• United Manufacturing Hub — The United Manufacturing Hub is an Open-Source Industrial IoT Infrastructure Platform enabling to easily connect, configure, manage, and maintain their factory.

Portfolio highlights

• Amenities Health — Amenities is the healthcare industry's leading Digital Front Door and patient loyalty platform. We help healthcare providers to acquire new patients and upgrade them to members. Our all-in-one patient app works with most modern EMRs to: 1) register new users into a full EMR account in <30 seconds with full identity verification and noduplicates, 2) help those patients find care options and book appointments with simple, conversion-optimized workflows, 3) seamlessly integrates key patient portal and 3rd party functions (i.e., video visits, secure messaging, test results, and billing), and 4) upgrade patients to members with custom experiences and services offerings (i.e., for Medicare Advantage, concierge memberships, direct-to-employer, or direct primary care patients)
• Cradle — Using robust prediction algorithms and AI design recommendations, Cradle assists biologists in rapidly designing better proteins. Cradle gives you complete ownership of the intellectual property while maintaining the privacy and security of your sequences and data.
• Leash Biosciences — We're transforming drug design with a rich dataset built by screening millions of compounds against thousands of protein to generate billions of data points, ideal for training advanced machine learning models.

Portfolio highlights

• SolveAI —
• Rowspace — Specialized intelligence for investors. Compound your firm's edge. We're hiring!
• Harmattan AI — Building the Future of Autonomous Warfare.

Portfolio highlights

• Exowatt — Modular full-stack renewable energy solutions for commercial and industrial customers.
• Preventive — Preventive mission is to determine whether the newest generation of gene editing technologies can be used safely and responsibly to correct devastating genetic conditions for future children.
• Red Queen Bio — Red Queen Bio is an AI biosecurity company. Think of us as the cybersecurity layer for biology. AI is making it dramatically easier to design powerful new drugs and therapies, which is extraordinary news for medicine. But the same tools are also lowering the barrier for bad actors to engineer dangerous pathogens, and opening up an entirely new category of threats, including viruses designed to evade human immunity.Defense has to keep pace with offense.

Portfolio highlights

• Mason America, Inc. — Mason is the device innovation platform for product leaders who dare to deliver the next innovation in their field.
• Cara — Cara is a domain-specific AI platform purpose-built for insurance—a modular system that enables agencies, brokerages, and MGAs to automate servicing, accelerate sales, and scale operations with a 24/7 digital workforce.
• Triangle Health — Triangle Health is a software company that uses artificial intelligence to analyze medical documents.

Portfolio highlights

• The Beans — The Beans offers a software application platform that creates personalized cash flow plans designed for its users. The Beans is Simplifying the path to financial balance through design and technology so that people can focus on what they love.
• NextSense — Introducing NextSense Smartbuds: EEG-powered earbuds that go beyond sleep tracking. Backed by science, Smartbuds provide real-time insights to help you achieve deeper, more restorative sleep. Comfortable, intuitive, and easy to use, Smartbuds empower you to wake up your best self.
• Openwater — OPENWATER - THE FUTURE OF NEURAL DIAGNOSTICS IN THE PALM OF YOUR HAND.

Portfolio highlights

• Hideout — Hideout makes high-quality food that is available for delivery. Danielle Sobel established the company in Los Angeles, California.
• Abalone Bio — Our Functional Antibody Selection Technology platform (FAST) taps into the potential of the body's biological activities, expanding the reach of antibody drugs.
• Altay Therapeutics — Pioneering the first oral drug for FSHD and advancing cancer treatment solutions.

Portfolio highlights

• Scoop — Thrive in a hybrid work environment with Scoop's solutions for Workplace Safety, Workplace Utilization, Team Coordination, Desk Management, and Commute.
• Crosby — The AI Law Firm Built for Execution. Lawyer-assisted AI to review MSAs, DPAs and NDAs in under an hour.
• Overwatch Research — Generate accurate in vivo study data as a part of your efficient, connected R&D.

Portfolio highlights

• Cache — Biomolecules are the next bits of the 21st century. So we're developing the first wet operating system for storing, accessing, and computing biomolecules at scale to make them widely accessible and useful. We're enabling the storage and access to the whole data universe—digital and biological—forever so that we don't have to deleteor dispose of anything ever again.
• Lamin — Open data platform for traceable multimodal AI. Query, trace, and govern data with a lineage-native lakehouse for files, tables, arrays, ontologies, and notes.
• General Proximity — The next generation of induced-proximity medicines. We're here to put a dent in the universe.

Portfolio highlights

• Stoicheia — Mattiq delivers innovative electrochemical solutions to decarbonize the fundamental building blocks that power our world.
• Exicure — Exicure is Formerly Known as AuraSense Therapeuticsis. Exicure is developing a new class of immunomodulatory and gene silencing drugs against validated targets. Our 3-dimensional, spherical nucleic acid (SNA™) architecture unlocks the potential of nucleic acid therapeutics in multiple organs. Our lead programs address diseases from inflammatorydisorders to oncology.SNA constructs overcome one of the most difficult obstacles to nucleic acid therapeutics: safe and effective delivery into cells and tissues. SNA constructs exhibit unparalleled transfection efficiency into numerous cell and tissue types including the skin without carriers or transfection agents. Moreover, SNAs can be used as potent immunotherapeutic agents for the treatment of cancer or infectious disease.

Portfolio highlights

• AppliedXL — Applied XL is an information company that uses machine learning and editorial algorithms to anticipate disruptions to the health of people, places and planet.

Portfolio highlights

• VerImmune — Located in Baltimore, Maryland, VerImmune is an Immuno-Oncology company developing a first-in-class cancer therapy known as Anti-tumor Immune Redirection. This strategy utilizes a proprietary tumor-specific, tumor type agnostic, virus-inspired platform termed Anti-tumor Immune Redirection Virus-inspired Particles (AIR-ViPs) that redirectspre-existing pathogenic or childhood vaccine immune memory towards tumors.
• SmartWorx — Enterprise no-code platform. Build governed, AI-powered enterprise applications without writing a single line of code. Not bolted on. Built in.
• GlucoTrack — GlucoTrack is a medical device manufacturing company that specializes in developing a non-invasive glucose monitoring devices. It has developed a medical device that measures glucose levels using three non-invasive technologies, ultrasound, thermal, and electromagnetic.

Portfolio highlights

• Athelas — Our breakthrough technologies provide clarity on a patient's most important health metrics, all while increasing revenue for your practice.
• Burrow — Meet Burrow. We make clever, uncompromising furniture and other nice things fit for modern life at home. From our comfortable, customizable sofas, sectionals, loveseats, and armchairs to our fashionable, functional rugs and tables, and five unique collections of decorative pillows and throw blankets, Burrow is the perfect place to start when shopping for your home.
• Innerwell — Innerwell combines personalized guidance from licensed therapists like you with the expansive power of psychedelics to treat anxiety and depression.

Portfolio highlights

• Stedi — Stedi is the only programmable healthcare clearinghouse. We offer modern, AI-ready APIs for eligibility checks, claims, transaction enrollment, and more.
• Fuel — Keunggulan Rumtar88slot ada pada akses stabil, tampilan mobile friendly, keamanan, dan layanan profesional untuk pengalaman slot online nyaman.
• Trilobio — Biology is the future, but most lab technology is stuck in the past. Trilobio is rebuilding the biology lab from the ground up to unlock its true potential.

Portfolio highlights

• Centivax — Centivax is a healthcare-based agency that provides biotechnology, pharmaceutical, medical device manufacturing, and therapeutic services.
• The Interaction Company of California — The proactive AI assistant in your iMessage, WhatsApp, and more. Texts like a human, really knows you, and integrates with your life in dozens of ways.
• SendCutSend — SendCutSend is an online custom manufacturing service specializing in rapid, high-precision sheet metal fabrication and CNC machining. Customers simply upload their digital design files to get professional-grade parts manufactured and shipped to their door, with turnaround times as fast as 24 hours.

Portfolio highlights

• Cleerly — Cleerly is a healthcare company whose mission is to create digital care pathways to prevent heart attacks. The company develops a new standard for coronary artery disease by integrating quality clinical science with the latest-generation AI, in order to offer actionable clinical insights to every stakeholder in the heart care pathway.Throughthese data-driven solutions, the company aims to provide a comprehensive solution for cardiovascular disease evaluation that offers value to the healthcare system and improves heart health for patients at risk of heart attacks.
• Litterati — Litterati is an app that encourages users to pick up and track litter.The app plans to let users join groups, so that schools, clubs, and other communities can track their collective efforts rather than having to go solo. It will also introduce maps, so litter-pickers can see what else is being picked up in their neighborhoods.
• Kingdom — Kingdom Supercultures create microbial cultures that help food manufacturers to create new foods with boosted benefits. It re-assembles nature's microbes into new combinations, creating plant-based foods that taste like dairy, low-alcohol beverages with full flavor, and natural preservatives that work as well as artificial ones.They workwith clients across diverse industries including food, beverage, personal care, beauty, and more. Their technology comprises an expansive biobank of GRAS microbial strains, high-resolution strain characterization, and new algorithms for predicting and assembling microbial communities.

Portfolio highlights

• Moonlake AI — Vibe code games and worlds into existence.
• Belfort — Enabling Fully Homomorphic Encryption through Hardware Acceleration
• Periodic Labs — From bits to atoms.

Portfolio highlights

• Athelas — Our breakthrough technologies provide clarity on a patient's most important health metrics, all while increasing revenue for your practice.
• Deep Infra — Deep Infra offers cost-effective, scalable, easy-to-deploy, and production-ready machine-learning models and infrastructures for deep-learning models.
• Alchemy — Whether you're a beginner, working on a side project, or one of the largest teams in the blockchain space, Alchemy makes Ethereum development easy with enhanced APIs, node infrastructure, and developer tooling. Get started for free!

Portfolio highlights

• NavigateAI — An AI copilot for every person in the field. NavigateAI upskills and coaches your team, runs real-time quality control, manages the project in the background, and provides expert knowledge, instantly.
• Harvey — Harvey is an artificial intelligence technology service provider.
• Socket — Socket fights vulnerabilities and provides visibility, defense-in-depth, and proactive supply chain protection for JavaScript, Python, and Go dependencies.

Portfolio highlights

• Spike Neuro — We seek to provide equitable access to development resources so all researchers have the opportunity to impact the neuroscience community.

Portfolio highlights

• Slate Auto — We built it. You make it. A simple, affordable personalized truck (or SUV, your call). Put down a deposit today and lock in your delivery timing.
• Re:Build — Re:Build Manufacturing helps organizations move from concept to full-scale production by uniting design, engineering, and manufacturing to bring innovative products to market.
• Colossal Biosciences — The science of genetics. The business of discovery.

Portfolio highlights

• Athelas — Our breakthrough technologies provide clarity on a patient's most important health metrics, all while increasing revenue for your practice.
• Burrow — Meet Burrow. We make clever, uncompromising furniture and other nice things fit for modern life at home. From our comfortable, customizable sofas, sectionals, loveseats, and armchairs to our fashionable, functional rugs and tables, and five unique collections of decorative pillows and throw blankets, Burrow is the perfect place to start when shopping for your home.
• Arkive — Arkive is a web3 museum of real world items, curated by a community of passionate hobbyists, collectors, artists, designers, and creators.

Portfolio highlights

• Key — Unlock new networking and career opportunities with Key, the leading AI-powered professional networking platform. Build and manage communities, host and join exclusive events, and create meaningful connections to supercharge your growth all in one place.
• Matic — The world's most advanced floor cleaner. Your home's best helper.
• Bluenote Health — Accelerate innovation with AI built for and trusted by leading life sciences companies.

Portfolio highlights

• FlyMy.AI — Real-time AI cloud
• Medra AI — Building robotics to accelerate scientific breakthroughs. At Medra, our mission is to automate repetitive wetlab tasks so scientists can more easily collect data and run the experiments needed to make groundbreaking scientific discoveries.
• Periodic Labs — From bits to atoms.

Portfolio highlights

• Vizgen — The next generation of genomics, expanding the impact of spatial context and demonstrating the potential of in situ single-cell spatial genomics.
• Stoicheia — Mattiq delivers innovative electrochemical solutions to decarbonize the fundamental building blocks that power our world.
• Torus Biosystems — Torus Biosystems offers an apparatus for DNA testing for scientific and medical research purposes in the fields of consumer products, food for human beings or animals, hygienic and beauty care for human beings or animals, agriculture, horticulture, and forestry. The company was founded in 2019 and is headquartered in Cambridge, Massachusetts.

Portfolio highlights

• Tierra Biosciences, Inc. — Speed, scale and simplicity with protein synthesis on-demand. Discover your portal to thousands of custom proteins. Get testable material with a single input.
• Tierra Biosciences — Speed, scale and simplicity with protein synthesis on-demand. Discover your portal to thousands of custom proteins. Get testable material with a single input.

Portfolio highlights

• Vorflux — Cloud agents that ship production code. An opinionated harness that runs the full SDLC on dedicated machines.
• BizScout — BizScout is an online platform of Off market deals for verified buyers and sellers.
• Warp — Warp is a payroll and compliance tool that makes it easy for founders to hire, onboard, and pay their employees.

Portfolio highlights

• Pelgo — Pelgo is a startup that provides AI-powered career transition services. For employees coming out of layoffs, young grads just entering the job market, or full-time professionals trying to adjust to a developing AI-driven economy, its tools, along with human advisors, help onboarding, transition, and reskilling.
• howie — Howie is an AI calendar secretary for email, SMS, iMessage, Gmail, and Google Calendar. He books meetings, protects focus time, follows up, and handles reminders.
• Self Protocol — Self is spearheading a secure, human-first internet by allowing users to verify their identities while maintaining their privacy. Self Protocol is an identity and proof-of-humanity solution that uses zero-knowledge technology to confirm personhood and distinctive traits, like age and nationality, without revealing private information.

Portfolio highlights

• Quibim — Quibim builds AI tools that turn MRI, CT and PET data into actionable predictions for hospitals and biopharma. Trusted in 230+ centers worldwide.
• Nuclera — Nuclera offers a protein prototyping system to accelerate drug discovery by making proteins readily available to researchers. Nuclera's eProtein DiscoveryTM system allows scientists to rapidly produce and test proteins for drug discovery.
• 52 North Health — At 52 North we are developing fully-integrated clinical, AI and medical-device based systems.

Portfolio highlights

• Alex AI — Alex is the AI recruiter that puts sourcing, screening, and scheduling on autopilot. Fast-track vetting so you interview the best in days.
• TextQL — TextQL is you personal virtual data analyst, built for enterprise and powered by AI. Ask in natural english and Ana can build insightful analysis, stunning charts, and powerful models, all with enterprise-grade security.
• Raindrop — Monitor your AI Agent the right way. Get alerted when your agent fails in production, trace exactly what went wrong, and prove your fix worked.

Portfolio highlights

• CollX — Snap photos of them and instantly get the current market price. Add them to your collection and track your overall portfolio value.
• Collectors — The infrastructure that powers trust, security, and opportunity in collectibles.
• Iterative Health — Iterative Health is a healthcare technology and services company that focuses on accelerating clinical research to improve patient outcomes through innovative approaches. The company transforms gastrointestinal (GI) care by utilizing AI-driven clinical trials and diagnostics, significantly enhancing access to vital treatments.

Portfolio highlights

• CND Life Sciences — CND advances neurodiagnostics through skin biopsy testing, including the Syn-One Test, for neurodegenerative diseases.

Portfolio highlights

• Blue — An Operating System for your Personal Health. Join the waitlist here.
• UrbanKisaan — UrbanKisaan builds vertical farms in India and sells the produce directly to consumers via subscription based app. The farms create a positive change at every step from seed to store ensuring quality and traceability. They grow fresh veggies locally produced which are grown without using soil using 95% less water. It aims to create a sustainablefuture for farming and feed the world in a way that is good for both people and the planet.It was founded in 2017 and is headquartered in Hyderabad, Andhra Pradesh, India.
• Colossal Biosciences — The science of genetics. The business of discovery.

Portfolio highlights

• VitaDAO — Join VitaDAO, a community owned collective funding early stage longevity research. We fund and commercialize longevity therapeutics.
• Spring Discovery — Giving Scientists AI Superpowers

Portfolio highlights

• Authorea — Authorea is a provider of a collaborative platform that is designed to read, write, discuss, and publish research. Its platform serves as a powerful document editor for researchers and provides collaborative editing, automatic citation formatting, tracking changes and it has the ability to make any document public or fully private that enablesresearchers to write documents together and attach references, figures, data, and source code. It improves how researchers work and make breakthrough discoveries by tackling one of the most important parts of the research cycle which is communication.
• CourseHorse — CourseHorse is a provider of a learning platform used to centralize the learning opportunities. Its platform partners with providers of Spanish lessons, cooking courses, yoga classes, and other classes to create a single destination for people seeking personal interest education that enables people to increase ease and confidence in discovering thepath to personal enrichment.It was founded in 2011 and is headquartered in New York.
• Boundless Mind — Thrive Global's mission is to end the burnout epidemic with sustainable, science-based solutions that unlock employee performance and enhance well-being through our behavior change technology.

Portfolio highlights

• HUBUC — A single API-platform that allows any business to embed financial services capabilities into their products. 
e.g Uber can issue branded credit cards for all Uber drivers and Walmart provides customers a simple way to better manage and control their everyday finances, with no regulatory burden or compliance requirements in a few weeks.
• point.me — Search and book award flights and maximize the value of your points. Travel on points for less with point.me's flight award search tool.
• PlayerZero — PlayerZero builds a production world model so SRE, QA, and support resolve incidents, prevent defects, and close tickets faster. Trusted by Verizon & Zuora.

Portfolio highlights

• 54gene — 54gene is a healthcare startup unlocking the African genome to fuel genetic research and development that may lead to new discoveries and benefit all populations.54gene was founded in 2019 by Dr. Abasi Ene-Obong to address the significant gap in the global genomics market: Nearly 90% of genetic material used in pharmaceutical research iscaucasian. Only 2% is African, despite the fact that Africans and people of African ancestry are more genetically diverse than all other world populations combined. As a result, pharmaceutical research and development is lacking the diverse data that may hold the key to medical discoveries and new healthcare solutions.
• Betterhalf — Best matrimony app in India with AI matchmaking. Get compatible life partner from lakhs of genuine, Govt ID and selfie verified profiles of brides & grooms. Download Betterhalf marriage app now!
• SOS Hydration — Rescue yourself from dehydration with SOS, doctor formulated rapid hydration with 80x less sugar than sports drinks and only 3g carbs and 10 calories.

Portfolio highlights

• Kytopen — Kytopen is pioneering a novel and non-viral process to engineer human cells for therapeutic applications in immuno-oncology and genetic disorders.
• Erbi Biosystems — Erbi Biosystems is a transformative microfluidic bioprocess instrumentation company.
• 64x Bio — A comprehensive platform and product suite for advanced therapeutics.

Portfolio highlights

• Allara — Allara is your all-in-one virtual care team for hormonal, metabolic & gynecological conditions such as PCOS and Endometriosis.
• Systole Health — Join Systole Health and take control of your heart health. Our personalized group virtual care combines expert-led medical treatment with the power of community support.
• Parakeet Health — Parakeet Health is a AI contact center agent for healthcare practices.

Portfolio highlights

• GRAI — GRAI is an AI music research company building interactive music products
• Yope — Salo is a discussion platform that erases the borders for people with diverse opinions to let anyone speak up and be heard.
• DreamApp — Unlock the meaning of your dreams with DreamApp's dream interpretation. Discover the symbolism behind common dreams with our dream dictionary. Explore Now!

Portfolio highlights

• Humera — Humera - AI CAPTCHA That Knows You're Human
• Allonic — Allonic is a robotics hardware company pioneering 3D Tissue Braiding, a new manufacturing platform for producing integrated, compliant, bio-inspired robotic bodies through a single, fully automated production process. By eliminating assembly-heavy designs and supply-chain complexity, Allonic enables significantly faster iteration, lower costs, andsafer, more dexterous robots to be built. Originally founded from Hungary and operating internationally with a US HQ and a growing team of 15, Allonic is building the hardware foundation for the next generation of intelligent machines.
• Heywa Labs — Heywa Labs develops Generative UX (GenUX), an AI-driven interface layer that creates dynamic, adaptive user experiences beyond static text or links. Their flagship app, Heywa, delivers visual, tappable "stories" of cards for tasks like cooking, travel, fitness, and DIY, reconfiguring in real-time based on user interactions.

Portfolio highlights

• dub — The first Copy-Trading platform for stocks. Copy anyone's investments. For free. Regulated Broker-Dealer member FINRA and SIPC & FDIC insured.
• Primer — Primer is the world's first community built for curious and ambitious kids to find and explore their interests together.
• Coinbase Token Manager — LiquiFi helps crypto companies automate token vesting, issue token grants in compliance, and manage their token cap table.

Portfolio highlights

• Advex AI — Composer is a no-code AI vision system that enables industrial teams to train, deploy, and manage complex visual inspection tasks across manufacturing lines. Composer uses VLMs and synthetic data to achieve production performance in minutes.
• RapidClaims — Rapid Claims helps businesses autonomously code medical charts, find up-coding opportunities, improve the CDI process and reduce denials.
• Empower Sleep — Empower Sleep provides personalized sleep care online

Portfolio highlights

• Xplore — Xplore is flying commercial missions in Earth orbits with their XCRAFT™, and they invite you to join us. They take civilian, commercial and national security payloads to their desired orbit around Earth for their science or reconnaissance missions.
• LeoLabs — LeoLabs' network of ground-based, phased array radars produces high-resolution data on objects in LEO, supporting satellite service industries.
• Space Forge — Space Forge make super materials in space that cannot be made on earth.

Portfolio highlights

• ImaliPay — ImaliPay is a financial health platform offering financial products to freelancers and blue collar gig workers in partnership with gig platforms.
• QuadriBot — QuadriBot is an engineering company specializing in the design and development of electronics and automation technology, real-time systems and the development of IT and electronic solutions around smart transportation issues. We focus on robotics and autonomous vehicles as well as any mobile platfo.
• Nanotronics Imaging — At Nanotronics we provide customized solutions for automated optical inspection, process control, and security. Learn more about what we can do for you.