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Top 5 Medical Angel Investors in Italy in September 2025

Last updated: Sep 2025 A list of 5 angel investors that invest in Medical startups based in Italy. We rank investors based on the number of investments they made in Medical companies from Italy. We update this investor list every month.

Top 5 Medical Angel Investors in Italy in September 2025

Investor	Medical Italy investments
Luca Trevisan	2
Rosario Bifulco	1
Andrea Venturelli	1
Giovanni Leo	1
Barbara Castellano	1

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Investor list

Luca Trevisan Sales Manager and Business Coordinator.

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Investment focus

Medical, Health Care, Medical Device
Series A
Italy

Portfolio highlights

I-VASC — I-VASC has developed the VELEX device using new technology to treat CVI and varicose veins.

Rosario Bifulco, president of the auction house Finarte S.p.A.

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Investment focus

Art, Medical, Blockchain
Seed, Pre-Seed, Series A
Italy

Portfolio highlights

I-VASC — I-VASC has developed the VELEX device using new technology to treat CVI and varicose veins.
Reasoned Art — Reasoned Art is the Italian gallery dedicated to CryptoArt. it selects the best digital artists worldwide, curates physical and virtual exhibitions, and certifies the authenticity of works allowing their sale through NFT.

Andrea Venturelli - Venture Partner @ Innogest Capital

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Investment focus

Art, Events, Retail
Seed
Italy, United States

Portfolio highlights

Arcadia Earth — WHAT IS IT? Arcadia Earth is a large scale multi-sensorial journey through underwater worlds, fantasy lands, and inspirational art installations.
CV Lab — CV Lab is the first incubator fully focused on cardiovascular innovation in Europe. It supports the most promising ideas through patenting, prototyping, and proof of concept until they mature enough to give life to a spin-off and meet international capitals. CVLab puts to good use the experience of entrepreneurs and specialists with strongexpertise in biomedical. The company collaborates with experts in the field. CVLab is a lean organization, close to researchers and clinical needs.

Giovanni Leo is the Partner at Efficient Frontier Investing.

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Investment focus

Health Care, Medical Device, Medical
Seed, Series B, Series A
Switzerland, Italy

Portfolio highlights

EBAMed — EBAMed SA is a Swiss startup based in Geneva whose mission is to enable safe and effective non-invasive treatments of heart arrhythmias with protontherapy. The company is currently developing a medical device to enable non-invasive heart motion imaging and real-time synchronization of the therapeutic beam. This device consists in both hardware andsoftware components and expands treatment possibilities for existing protontherapy centres, enabling them for the first time to treat heart patients.
Hylomorph — Hylomorph is a clinical-stage medical device company developing innovative materials designed to transform the biocompatibility of implantable medical devices.
CV Lab — CV Lab is the first incubator fully focused on cardiovascular innovation in Europe. It supports the most promising ideas through patenting, prototyping, and proof of concept until they mature enough to give life to a spin-off and meet international capitals. CVLab puts to good use the experience of entrepreneurs and specialists with strongexpertise in biomedical. The company collaborates with experts in the field. CVLab is a lean organization, close to researchers and clinical needs.

Barbara Castellano of Panakes Partners.

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Investment focus

Health Care, Medical Device, Medical
Series A, Series B, Seed
Italy, Switzerland

Portfolio highlights

Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
Bio4Dreams — Il primo incubatore italiano certificato di startup innovative in fase very early stage, a capitale totalmente privato, dedicato alle Scienze della Vita.
Approxima — Approxima medical is developing a novel treatment for patients with tricuspid valve regurgitation

Investors by industry

Artificial intelligence

Venture Capital

Financial Services

Food and Beverage

Enterprise Software

Mobile Advertising

Wine And Spirits

Renewable Energy

Machine Learning

Agriculture (agtech)

Media (entertainment)

Investors by country

Russian Federation

Dominican Republic

United Arab Emirates

Marshall Islands

Angel Investors in Italy by industry

Venture Capital

Financial Services

Wine And Spirits

Artificial intelligence

Agriculture (agtech)

Media (entertainment)

Food and Beverage

Machine Learning