Top 15 Biotech Angel Investors in Italy (November 2026)

Portfolio highlights

• Freatic — Freatic builds decentralized products around untapped information markets.
• Niulinx — Politecnico di Milano spin-off building autonomous driving technology.
• Automated Architecture — A global ecosystem of automated micro-factories, to deliver sustainable, affordable and beautiful architecture to millions of people.

Portfolio highlights

• Pillar — Il sistema operativo per l'edilizia del futuro: dove innovazione, finanza e tecnologia si incontrano. Prenota il tuo appuntamento e trasforma la tua impresa edile
• Quisto — On Quisto, Ho.Re.Ca. retailers can find the best suppliers in their area and purchase 24/7 whatever they need for their business --> www.quisto.it
• CaSRevolution — A novel disease-modifying approach against neurodegeneration

Portfolio highlights

• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
• Bio4Dreams — Il primo incubatore italiano certificato di startup innovative in fase very early stage, a capitale totalmente privato, dedicato alle Scienze della Vita.
• Approxima — Approxima medical is developing a novel treatment for patients with tricuspid valve regurgitation

Portfolio highlights

• CitizenX — CitizenX is the secure and private platform that helps you diversify your passport portfolio, ensuring a safe future for you and your loved ones.
• Talyn Air — Inspired by two-stage rockets, our innovative eVTOL uses two flight vehicles to transform flight. Fixed-wing performance with VTOL capabilities.
• CaSRevolution — A novel disease-modifying approach against neurodegeneration

Portfolio highlights

• Immagina Biotechnology — Immagina BioTechnology is a StartUp hosted in the Laboratory for Biomolecular Sequence and Structure Analysis for Health (LaBSSAH), a hub comprising private and public institutions: the Bruno Kessler Foundation (FBK), the Institute of Biophysics of the Italian National Research Council (CNR-IBF) and the Centre for Integrative Biology of theUniversity of Trento (CIBIO). Immagina represents a unique opportunity to profitably match the academic know-how and industrial needs.

Portfolio highlights

• TENSIVE — Tensive is a biomedical startup established in 2012 to develop innovative prostheses aiming to offer a natural breast reconstruction or augmentation.Tensive is a biomedical startup established in 2012 to develop innovative prostheses aiming to offer a natural breast reconstruction or augmentation.

Portfolio highlights

• ChemiCare — Cutting-edge drugs for calcium-related diseases such as Tubular Aggregate Myopathies, Duchenne Muscular Dystrophy, and Acute Pancreatitis.
• Bio4Dreams — Il primo incubatore italiano certificato di startup innovative in fase very early stage, a capitale totalmente privato, dedicato alle Scienze della Vita.

Portfolio highlights

• Kellify — Kellify is the science-centric scale-up revealing visual experiences that strike human senses. Through a blend of AI and Neuroscience, Kellify uncovers the most compelling contents for the eyes -- from magnetic OOH campaigns or fancy tv series covers, to captivating movies, charming trends of properties, or dizzying works of art. Founded in 2018by Francesco Magagnini (CEO) and Fabrizio Malfanti (Chief AI Officer), Kellify raised $4.5 million in an early-venture round. Based in Genoa, IT (Headquarter) and Seoul, KR, Kellify currently has a 35+ fast-growing team ranging from data scientists and digital enablers.

Portfolio highlights

• Immagina Biotechnology — Immagina BioTechnology is a StartUp hosted in the Laboratory for Biomolecular Sequence and Structure Analysis for Health (LaBSSAH), a hub comprising private and public institutions: the Bruno Kessler Foundation (FBK), the Institute of Biophysics of the Italian National Research Council (CNR-IBF) and the Centre for Integrative Biology of theUniversity of Trento (CIBIO). Immagina represents a unique opportunity to profitably match the academic know-how and industrial needs.

Portfolio highlights

• Cogna — Cogna offers an AI-powered SaaS platform that streamlines the integration of data across several business domains.
• NXRT — Driving simulations for sales and training
• Fractile — Fractile is building chips to run large language models two orders of magnitude faster. Existing hardware is good for training LLMs, but very poorly suited to subsequent inference of the trained model, which is increasingly the dominant workload. A network’s weights need to be moved onto a chip once per word generated, and this movement takes a fewhundred times longer than the subsequent computations themselves. Fractile’s revolutionary approach to fusing computation with memory eliminates this bottleneck, and can scale to allow running the world’s largest models at a global scale.

Portfolio highlights

• Kellify — Kellify is the science-centric scale-up revealing visual experiences that strike human senses. Through a blend of AI and Neuroscience, Kellify uncovers the most compelling contents for the eyes -- from magnetic OOH campaigns or fancy tv series covers, to captivating movies, charming trends of properties, or dizzying works of art. Founded in 2018by Francesco Magagnini (CEO) and Fabrizio Malfanti (Chief AI Officer), Kellify raised $4.5 million in an early-venture round. Based in Genoa, IT (Headquarter) and Seoul, KR, Kellify currently has a 35+ fast-growing team ranging from data scientists and digital enablers.

Portfolio highlights

• Diamante — Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.

Portfolio highlights

• Immagina Biotechnology — Immagina BioTechnology is a StartUp hosted in the Laboratory for Biomolecular Sequence and Structure Analysis for Health (LaBSSAH), a hub comprising private and public institutions: the Bruno Kessler Foundation (FBK), the Institute of Biophysics of the Italian National Research Council (CNR-IBF) and the Centre for Integrative Biology of theUniversity of Trento (CIBIO). Immagina represents a unique opportunity to profitably match the academic know-how and industrial needs.

Portfolio highlights

• Immagina Biotechnology — Immagina BioTechnology is a StartUp hosted in the Laboratory for Biomolecular Sequence and Structure Analysis for Health (LaBSSAH), a hub comprising private and public institutions: the Bruno Kessler Foundation (FBK), the Institute of Biophysics of the Italian National Research Council (CNR-IBF) and the Centre for Integrative Biology of theUniversity of Trento (CIBIO). Immagina represents a unique opportunity to profitably match the academic know-how and industrial needs.

Portfolio highlights

• Immagina Biotechnology — Immagina BioTechnology is a StartUp hosted in the Laboratory for Biomolecular Sequence and Structure Analysis for Health (LaBSSAH), a hub comprising private and public institutions: the Bruno Kessler Foundation (FBK), the Institute of Biophysics of the Italian National Research Council (CNR-IBF) and the Centre for Integrative Biology of theUniversity of Trento (CIBIO). Immagina represents a unique opportunity to profitably match the academic know-how and industrial needs.