Top 50 Medical Angel Investors in Canada (September 2026)

Portfolio highlights

• Outway — Inspiring personal bests.
• Impro — Impro.AI accelerates business performance and growth with AI-powered insights and executive-level daily guidance, optimizing strategies to maximize revenue.
• Cognito Health — Canada's only integrated online mental health solution. Accessible and affordable treatment for your mental health. Book a free initial assessment today.

Portfolio highlights

• Molecular You — Get a full report on your risk in 26 health areas such as diabetes, Alzheimer's and heart disease. Lifestyle coaches are on hand for support and guidance throughout your program.

Portfolio highlights

• Hemi Labs — Hemi (https://hemi.xyz) is a modular protocol that integrates Bitcoin and Ethereum to amplify and extend the core capabilities of the two leading blockchain networks. This offers a novel perspective on blockchain interoperability and scaling by approaching Bitcoin and Ethereum as components of a single supernetwork. The result providessecurity that exceeds that of Bitcoin (“superfinality”) and new levels of blockchain programmability, portability, and potential. Hemi was co-founded by Jeff Garzik (former Bitcoin core developer) and Max Sanchez (inventor of the Proof-of-Proof consensus protocol), and is surrounded by a team of renowned blockchain engineers, strategic partners and investors.
• Sapien — Sapien offers Data Labelling Services with RLHF to fine-tune your LLMs potential. Improve model performance with better data to improve outcomes. Consult us now!
• Movement Labs — Movement Labs is on a mission to create a global community of Move Builders, working together to improve decentralized network user experience.

Portfolio highlights

• SomaDetect — SomaDetect measures every critical indicator of dairy quality (fat, protein, somatic cell counts, progesterone) from every cow at every milking. It uses no consumables (no chemicals, no cartridges, no lost milk), is extremely quick (results in seconds, not minutes), and accurate.
• PayShepherd — PayShepherd helps manage contractor billing for industrial facilities and simplifies billing processes. Save time, money, and headaches.
• StellarAlgo — Drive fan engagement and revenue across the entire fan journey. For Major Leagues, Emerging Leagues, Live Events, Media & Gaming, and Corporate Partnerships.

Portfolio highlights

• Shakepay — Shakepay allows Canadians to buy/sell bitcoin and pay their friends. We're on a mission to create open access to building wealth.
• Platformatic — OpenSource Platform for ...
• Schematic — Schematic is a billing platform that provides entitlement management, metering, pricing, packaging, and billing UI in one place, built for product developers and commercial teams.

Portfolio highlights

• Afropunk — Afropunk LLC is a fest and newsletter which provides entertainment solutions in music, art, and politics.
• Arcade — Arcade is a B2C platform that transforms the jewelry market through its prompt-to-product solution, allowing users to create unique designs using AI. The marketplace supports various user roles, enabling customers, designers, and influencers to engage and collaborate.
• Jane Technologies — Jane Technologies is a cannabis retail tech company that provides its consumers with a confident, safe and simple shopping experience. Users can browse local products in real-time, compare by price, proximity or popularity and place orders at local stores for free. Jane partners with dispensaries on a win-win basis; stores only pay for completedorders at a fraction of the price of other industry software.

Portfolio highlights

• COR — COR is the management platform for agencies and consultancies. Automate time tracking, visualize profitability in real time, and scale with AI.
• ZYTLYN Technologies — Headquartered in Geneva, Switzerland, ZYTLYN is a data analytics and AI company, helping customers address their most urgent problems and opportunities with granular, qualified, and actionable data, predictions and insights. Its Prediction as-a-Service product gives customers the ability to optimize critical decision making through predictiveinsights. Together with customers, ZYTLYN is helping the world’s largest industries adapt, recover and grow faster, with a total addressable market of close to $50 billion.
• HotelRunner — HotelRunner is a cloud based hotel online sales and channel manager tool with an online marketing suite. Power your online sales now!

Portfolio highlights

• Plentina — Plentina is a fintech startup accelerating access to credit in emerging markets. We enable consumers to build their credit history while making easier payments to their favorite merchants.
• BlockFi — BlockFi is a secured non-bank lender that offers USD loans to crypto-asset owners who collateralize the loan with their crypto-assets. Their products bring additional liquidity to the blockchain asset sector and meet the needs of both individuals and institutions holding blockchain assets. BlockFi holds clients' Bitcoin and Ether with aregistered custodian and issues loans in USD to their bank accounts. Currently operating in beta launch, lending in 35 US states to retail investors and companies.BlockFi’s mission is to provide liquidity, transparency, and efficiency to digital financial markets by creating products that meet the needs of consumers and corporations across the globe. They leverage a sophisticated infrastructure that integrates with multiple blockchains, they plan to expand their product set based on their retail and institutional client's needs.
• Eden Health — Eden integrates with your company's health insurance. Get 24/7 access to medical providers, personalized benefits navigation, and COVID-19 reopening solutions.

Portfolio highlights

• Pathway Medical — Pathway is an accurate and efficient point-of-care reference tool that gives you rapid access to evidence-based guideline summaries, interactive algorithms, key findings from landmark trials, clinical calculators, and more. Available anytime, anywhere.

Portfolio highlights

• Filmhub — Igniting opportunity for the visionary storyteller of today and tomorrow.
• Homecoming — A digital companion app for psychedelic therapy.
• Constructor — The only site search and product discovery built for ecommerce KPIs. Delivering superior experiences with AI, NLP, data and personalization.

Portfolio highlights

• Homecoming — A digital companion app for psychedelic therapy.

Portfolio highlights

• Eli — At-home hormone testing from Eli Health: track cortisol, progesterone, and testosterone with saliva tests that deliver lab-grade results in 20 minutes.
• AI Nexus — AI Nexus Inc. is a deep tech company that develops groundbreaking artificial intelligence technologies designed for use in industry-specific subsidiaries. Based on decades of building AI solutions for military and civilian applications, AI Nexus has created an advanced AI platform that enables the creation of a diverse range of collaborative AIapplications across the AI spectrum. Most commercially available AI is focused on machine learning, a subfield of AI that is best suited to recognizing patterns but not understanding them. As there is no understanding, machine learning can’t explain its thinking so can’t be given autonomy in complex life-or-death situations. Our technology can embody different AI techniques, algorithms and software from any source, can run autonomously in devices like IoT all the way up to the cloud (allows you to use whatever is out there).AI applications built with our technology will be able to observe the world, reason, make recommendations and even take autonomous action. Software that can sense, reason, act & learn
• Healthspan Digital —

Portfolio highlights

• Stat Labs — Stat Labs is a clinician-led research and deployment firm at the intersection of medicine and artificial intelligence.

Portfolio highlights

• MD HomeCall — MD HomeCall Inc. connects patients and physicians in the Greater Toronto Area. We arrange doctor house calls and visits. Call us today at 637-447-3317

Portfolio highlights

• Flipd — Flipd is the all-in-one productivity app makes you feel good about your progress. Keep track of your productivity, stay motivated, connect with others, and achieve your goals with Flipd.
• Pathway Medical — Pathway is an accurate and efficient point-of-care reference tool that gives you rapid access to evidence-based guideline summaries, interactive algorithms, key findings from landmark trials, clinical calculators, and more. Available anytime, anywhere.

Portfolio highlights

• Apron — You run payments. Not the other way round.
• Prenuvo — Changing the medical paradigm from sick care to proactive healthcare
• Gravity Sketch — Gravity Sketch is an intuitive 3D design platform for cross-disciplinary teams to create, collaborate, and review in an entirely new way.

Portfolio highlights

• Social Nature — Earn cash back on natural products at Walmart, Target, Whole Foods, Sprouts & more. Get free product trials (100% cash back) and high-value cash back offers. 1.2M+ members, paid in 48 hours.
• Cognito Health — Canada's only integrated online mental health solution. Accessible and affordable treatment for your mental health. Book a free initial assessment today.
• KOHO Financial — Open an everyday spending account online with instant cash back & premium rewards. Join over 1.5M Canadians using KOHO's prepaid Mastercard to spend, save, build and borrow. Sign up in minutes!

Portfolio highlights

• SiPhox Health — Painless, 5-minute biomarker testing at home. Clear insights, trend tracking, and a personalized plan built around your results.
• BuildForever — BuildForever build products that feel personal, magical and deeply human.
• Perplexity — Perplexity is a search engine platform that uses artificial intelligence to provide large language models and search engines. The company's platform enables the development of beneficial artificial general intelligence, as well as an open-source environment that is accessible to the public, allowing clients to develop skills and knowledge inartificial intelligence.

Portfolio highlights

• Shakepay — Shakepay allows Canadians to buy/sell bitcoin and pay their friends. We're on a mission to create open access to building wealth.
• Spatial — Experience virtual NFT art exhibitions, meetups, and live events together with lifelike avatars. Customize beautiful 3D spaces. Join now from Web, Mobile, & VR.
• Haloo — Navigating the trademark search and registration process can be daunting and onerous for business owners and entrepreneurs. Heirlume is the first self-serve online trademark search and registration platform that integrates sophisticated legal thinking with technology. We make the complex trademark search and registration process fast, accurate,trusted and affordable for entrepreneurs and enterprise/e-com partners. Our search tool instantly runs the country-specific legal tests (i.e., “likelihood of confusion”) and performs lawyer analysis. Intelligent search algorithms provide an at-a-glance opinion of registerability (conflicts, descriptiveness, obscenity), displayed in simple visuals. Distilling the multiple data sets involved with drafting a trademark application requires time-consuming legal analysis. Our machine learning auto-suggest trademark application builder performs the lawyer work and removes room for error. While our first go to market strategy will target SME individual users, we see huge potential in expanding our market reach through key B2B partnerships as an upsell/add-on to a domain purchase (GoDaddy), or store set-up (Shopify or Amazon). Ultimately, we believe we can make trademark registration quick, easy and affordable, similar to the experience of registering a domain.

Portfolio highlights

• Wingocard — Receive money instantly and shop at your favorite brands. No overdrafts, ever.
• Ditch Labs — Ditch Labs is a digital health company pioneering nicotine addiction treatment with artificial intelligence and a revolutionary device.
• Pathway Medical — Pathway is an accurate and efficient point-of-care reference tool that gives you rapid access to evidence-based guideline summaries, interactive algorithms, key findings from landmark trials, clinical calculators, and more. Available anytime, anywhere.

Portfolio highlights

• Seismic Therapeutic — Seismic Therapeutic is a biotechnology company integrating machine learning across the entire biologics discovery process to accelerate immunology drug development. Using its IMPACT™ platform, the company is addressing the central challenges of biologics discovery and development by fully integrating machine learning with the key elements ofbiologics drug discovery – structural biology, protein engineering, and translational immunology – to create optimized therapies on an accelerated path to patients. Seismic Therapeutic has an emerging pipeline of novel biologics to address adaptive immune system dysregulation to treat autoimmune diseases.
• Selecta Biosciences — Selecta Biosciences is a biopharmaceutical company developing the first generation of nanoparticle immunomodulatory drugs for the treatment and prevention of human diseases. Their proprietary product platform technology combines recent advances in immunobiology with cutting-edge nanotechnology to develop targeted immunomodulatory nanoparticles.Itwas founded in 2008 and is headquartered in Watertown, Massachusetts.
• Cartesian Therapeutics — Cartesian Therapeutics is a biotechnology company developing potent, safer cell and gene therapies for cancer and autoimmune diseases

Portfolio highlights

• Aquaria — Aquaria provides solutions to secure access to clean water. The organization adapts its approaches based on the needs of these communities. It addresses water-related challenges through various methods.
• Delphi — Delphi turns your expertise into an always-on presence, so you can grow your reach, serve your audience, and lead with clarity, without burning out.
• Cambridge Terahertz — Cambridge Terahertz, a leader in terahertz (THz) imaging technology, offers an AI-powered Concealed Weapons Detection (CWD) solution to enhance workplace security. Our patent-pending system can see through clothing, luggage, plastic, paper, ceramics, and cardboard to detect concealed threats, including firearms, knives, and explosives.

Portfolio highlights

• Quantified Citizen — Join groundbreaking studies, receive rich health insights and make an impact on global health and science. Download Quantified Citizen today!

Portfolio highlights

• Humera — Humera - AI CAPTCHA That Knows You're Human
• Allonic — Allonic is a robotics hardware company pioneering 3D Tissue Braiding, a new manufacturing platform for producing integrated, compliant, bio-inspired robotic bodies through a single, fully automated production process. By eliminating assembly-heavy designs and supply-chain complexity, Allonic enables significantly faster iteration, lower costs, andsafer, more dexterous robots to be built. Originally founded from Hungary and operating internationally with a US HQ and a growing team of 15, Allonic is building the hardware foundation for the next generation of intelligent machines.
• Heywa Labs — Two products, one engine. Heywa Studio for businesses, Heywa for anyone with a question worth following.

Portfolio highlights

• Practice — Sell your expertise online, and manage your business, all in one place.
• Cognito Health — Canada's only integrated online mental health solution. Accessible and affordable treatment for your mental health. Book a free initial assessment today.
• Windsor.io — Windsor lets sales and marketing teams improve conversion with personal videos. Record a single video, hook up your CRM and hit send. Our AI will create and send a personal video to every recipient

Portfolio highlights

• AssistIQ — Designed for simplicity and powered by computer vision and machine learning, AssistIQ Capture accurately tracks supplies and implants as they are used...
• Mercator AI — Our mission is to give business developers more time to do what they do best, and support them with the insights they need to have informed and productive conversations. We mine and analyze millions of construction data points across the project lifecycle so that our customers can confidently find and qualify projects and partners faster.Mercator is used by Architecture, Engineering, Construction, Real Estate, and Manufacturing companies to inform strategic and tactical decision making.Mercator AI is a privately held company that has recently closed a pre-seed round.

Portfolio highlights

• KeyOps — A revolutionary physician engagement platform that allows doctors to quickly share their expert opinions with healthcare stakeholders such as government institutions, hospitals, universities, and life science companies.

Portfolio highlights

• Everyrealm — Everyrealm is an immersive media company, specializing in technology and infrastructure that drives social, community-driven gaming experiences and platforms.
• Magic Spoon — Magic Spoon cereal is high-protein, low-sugar, keto-friendly, and gluten-free. Available in Cocoa, Frosted, Fruity, Blueberry, Peanut Butter, and Cinnamon.
• Altered State Machine — Altered State Machine, aims to be a platform and protocol which any developer can build on it; can create, own, and compete with AI-based agents (bots) and upgrade and train their AI, buy, and sell them as NFTs. This will bring an evolution for NFTS.

Portfolio highlights

• Taloflow — Taloflow analyzes 4,000+ vendor data points to provide you with the best possible recommendation for cloud object storage. Complete a 5-minute use case questionnaire to get started.
• SceneBox — SceneBox helps computer vision engineers sift through their large datasets to uncover the failure states and interesting data they need to train machine learning models faster.
• Quantified Citizen — Join groundbreaking studies, receive rich health insights and make an impact on global health and science. Download Quantified Citizen today!

Portfolio highlights

• World Labs — World Labs is an AI startup that can analyze visual data with comprehension akin to a person's, a substantial advancement above existing capacities.
• The Invention Network — ScaleIP is an IP business intelligence platform that helps companies monetize IP.
• Clair Health — Clair Health is building the first noninvasive wearable continuous hormone monitor. Track estrogen, progesterone, LH, FSH, and PdG in real-time. Join the Clair Health waitlist.

Portfolio highlights

• Pathway Medical — Pathway is an accurate and efficient point-of-care reference tool that gives you rapid access to evidence-based guideline summaries, interactive algorithms, key findings from landmark trials, clinical calculators, and more. Available anytime, anywhere.

Portfolio highlights

• Kenota Health — Kenota Health develops next-generation rapid point-of-care system intended to be used for allergy testing in humans. Kenota's diagnostic tools are safe, simple, and offer a cheaper alternative to allergy testing using a thorough non-invasive technology, enabling physicians to improve patient outcomes.

Portfolio highlights

• Locorum — Locorum is a business reward platform that provides cash back when hiring local services such as real estate, renovation, and mortgage.
• Cognito Health — Canada's only integrated online mental health solution. Accessible and affordable treatment for your mental health. Book a free initial assessment today.

Portfolio highlights

• Prenuvo — Changing the medical paradigm from sick care to proactive healthcare
• HumanCo — HumanCo is a mission-driven private holding company that invests in and builds brands focused on healthier living and sustainability.
• Katalyst — With one strength training session, you'll get a full-body workout in 20 minutes, with no external loads or joint impact. The Katalyst Training System uses low frequency impulses to stimulate and contract up to 90% of the muscle fibers in your body, for an intense workout equivalent to spending 2+ hours in the gym.

Portfolio highlights

• Swift Medical — Get advanced wound care powered by AI with Swift. 32M+ calibrated images enable 35% faster healing, 79% faster assessments, and 15% fewer hospitalizations.

Portfolio highlights

• Lora DiCarlo — Lora DiCarlo used biomimicry to translate human mouth, tongue, and finger-like haptics into microrobotic mechanisms that feel like a human partner. Osé adjusts to each woman's unique physiology for a personal fit that makes achieving the elusive blended orgasm easy.
• Molecule — Molecule is a collaborative platform, where stakeholders in drug development work together to accelerate the process of bringing novel therapeutics to patients. We connect leading researchers to investment opportunities by turning intellectual property and its development into a liquid and easily investable asset.
• MycoMedica Life Sciences, PBC — Psychedelic Medicines

Portfolio highlights

• Meticulous — Meticulous auto-generates and auto-maintains visual frontend browser tests, providing a level of coverage that is unattainable with manually written tests.
• ConfigHub Inc. — ConfigHub will unify and centralize software infrastructure configuration in a way that existing tools do not.
• Patronus AI — The industry-first automated evaluation platform that detects Large Language Model (LLM) mistakes at scale and use generative AI with confidence.

Portfolio highlights

• KeyOps — A revolutionary physician engagement platform that allows doctors to quickly share their expert opinions with healthcare stakeholders such as government institutions, hospitals, universities, and life science companies.
• Friendlier — Friendlier aims to reduce single-use plastic waste generated by disposable food packaging. We provide businesses with reusable plastic cups and containers, and take care of delivery, pick-up, and washing.
• PragmaClin — PragmaClin Research Inc. is aiming to help patients monitor their symptoms faster with the use of our remote patient monitoring system, PRIMS (Parkinson's Remote Interactive Monitoring System).

Portfolio highlights

• Saguaro Technologies — Saguaro Technologies offers innovative cell culture products that help scientists work with in vitro models that are more predictive of results in clinical trials with humans.

Portfolio highlights

• Workwolf — Workwolf is a recruitment services company that combines human recruiters with proprietary AI and psychometric technology to deliver predictive hiring intelligence at disruptive pricing. The company addresses a fundamental inefficiency in the $150B+ recruitment industry: traditional agencies charge 15-25% of candidate salary for subjectiveassessments with no performance accountability. Workwolf’s technology-enabled model delivers measurable quality improvements at significantly lower cost per hire. The proprietary technology platform includes two core components: Smart Resume Screening for contextual qualification matching, and Packfinder™ psychometrics for role-specific performance prediction. Unlike generic assessment tools, Packfinder™ models are calibrated using client performance data, creating organization-specific predictions that improve with scale. The business model starts at fees as low as 4% of annual salary for high-volume roles, rather than percentage-based fees of 15-25%, creating favorable unit economics for high-volume clients while maintaining strong margins through technology leverage. This pricing structure aligns incentives around retention rather than salary inflation. Target customers are mid-market companies with consistent hiring volume (2+ hires/month) across multiple locations—particularly retail, hospitality, healthcare, logistics, and call centers. These segments offer predictable demand and benefit most from Workwolf’s pattern recognition capabilities across distributed operations. The platform generates compounding data advantages: each hire provides performance outcome data that refines predictive models, creating a defensible moat as the system processes more hiring decisions within and across client organizations. Workwolf is headquartered in Toronto, Canada.
• Agile Devices — Agile Devices offer catheter-based interventional procedures helping patients during a stroke. It helps medical practitioners reduce the procedure time to respond to time bound emergencies.
• Traction Technology — Traction is a powerful SaaS collaboration platform for evaluating, adopting and managing new technologies across the enterprise. The platform includes Project Management and CRM tools designed specifically for enterprise teams tasked with discovering and evaluating new technologies. Traction is used by IT, Innovation and Corp Dev teams toaccelerate their digital transformation projects, and to speed up the way they find, manage, and adopt new technologies. Traction also offers On-Demand Research services delivered through its platform.

Portfolio highlights

• Zymeworks — Zymeworks Inc. is a publicly listed (NYSE: ZYME), clinical-stage, biopharmaceutical company dedicated to the discovery, development, and commercialization of next-generation multifunctional biotherapeutics, initially focused on the treatment of cancer.
• Finch Legal — Finch Legal is a software development company that supports personal injury law firms. The company aims to provide practical and effective legal solutions, as suggested by its commitment to serving clients better and more efficiently.
• Influitive — Our Customer Advocacy Saas product and professional services allow your company to strategically discover, nurture and mobilize customer advocates.

Portfolio highlights

• Guardly — Guardly designs and provides mobile safety solutions to help security teams better prepare for and respond to threats against people and key assets they protect. Guardly mobile safety apps available on Android, iPhone, Windows Phone and BlackBerry act as personal emergency phones that provide instant two-way communication with private security andauthorities. Guardly's mobile safety applications, indoor positioning system and mass notification technologies improve situational awareness by providing real-time indoor positioning / GPS data, caller identity and the nature of an incident — data otherwise not available to security operators. Guardly Command™ helps security operators monitor, manage and respond to real-time data, make more informed decisions and improve emergency response times by as much as 44 percent. Guardly is based in Toronto and is committed to improving emergency response and communication.
• Lawbrokr — Lawbrokr is a legal tech company focused on helping law firms pre-screen new leads so they don't waste time on consultations with prospects that aren't a fit.Lawbrokr provides a unique link that can be placed on a firm’s website and everywhere else that consumers search for lawyers. The link connects the legal consumer to a set ofqualifying questions crafted by the firm. With just a few clicks, the consumer gains an understanding of the services offered, and the firm can determine whether the prospective client is a fit for them. This allows the firm to invest its time into qualified prospects rather than dead end consultations.
• ManagingLife — Lowering the human and financial cost of chronic pain with its digital solution, Manage My Pain.

Portfolio highlights

• Sorare — Global Fantasy Football. Collect limited edition digital collectibles, Manage your team and earn prizes!
• Hoth Intelligence — Hoth Intelligence home page. Space age surgical technology brought down to earth.
• Floating Point Group — Floating Point Group is a trading platform provider offering innovative, industry-leading trade execution and settlement

Portfolio highlights

• Pioneer Fund — 300+ YC alumni investing in the top YC startups
• Avro — Avro Life Science is developing skin patches for generic drug delivery, focusing on therapeutics for children and the elderly. The core of our technology is a novel biopolymer which is used as a platform for passive transdermal drug delivery of small molecules and drugs.

Portfolio highlights

• Prenuvo — Changing the medical paradigm from sick care to proactive healthcare
• HumanCo — HumanCo is a mission-driven private holding company that invests in and builds brands focused on healthier living and sustainability.
• Katalyst — With one strength training session, you'll get a full-body workout in 20 minutes, with no external loads or joint impact. The Katalyst Training System uses low frequency impulses to stimulate and contract up to 90% of the muscle fibers in your body, for an intense workout equivalent to spending 2+ hours in the gym.

Portfolio highlights

• Leadoptik — Leadoptik is a California-based company is currently operating in stealth mode.
• Modality.AI — Modality.ai is an AI-powered platform that detects health conditions using conversational AI. Through dialogue and video, Modality.AI interacts conversationally with the patient to provide health assessment anywhere, anytime. Its system analyzes multimodal data which allows continuous screening and assessing of patients’ health.
• Gray Oncology Solutions — Gray Oncology Solution is a healthcare enterprise software company that commercializes GrayOS, the operating system for oncology.

Portfolio highlights

• Pharma in silica — Pharma in Silica develops pharmaceuticals in the preclinical stage. Pharma in Silica is now working on the regulatory applications for a multi-center Canada/US clinical trial for patients with advanced non-small cell lung cancer (NSCLC) as well as the preclinical safety and efficacy investigation of OpPacli.

Portfolio highlights

• Cherry Health — Cherry Health is your medical network. Where healthcare connects, finds jobs and more.

Portfolio highlights

• Swift Medical — Get advanced wound care powered by AI with Swift. 32M+ calibrated images enable 35% faster healing, 79% faster assessments, and 15% fewer hospitalizations.

Portfolio highlights

• Swift Medical — Get advanced wound care powered by AI with Swift. 32M+ calibrated images enable 35% faster healing, 79% faster assessments, and 15% fewer hospitalizations.