Top 50 Medical VC Funds & Investors in Italy (November 2026)

Portfolio highlights

• Evja — Evja supports growers in optimizing the management and monitoring of irrigation, nutrition and protection of their crops through the use of OPI, the most advanced system for precision agriculture .
• Phononic Vibes — The Art of Noise Management START NOW The Art of Noise Management START NOW Phononic Vibes Technology Working with the MetaMaterial technology, Phononic Vibes
• Tretau — E-mobility is powered by its core - the electric motor. We at Tau are at the very core of the core: the copper winding wire, the magnetic core, the electrical steel.We just make it bet.

Portfolio highlights

• Cato AI — Search, analyze and bid on Italian public tenders with AI, automating the manual work for bid offices and sales teams.
• AUDIOGEN — Generate your sounds with AI. Create an infinite world of sounds - sound effects, samples, and music, instantly. Get Started Free.
• Alomana — Alomana is an organization that focuses on harnessing the power of artificial intelligence and data analytics to drive insights and innovation across various industries. They offer a range of services, including data analysis, machine learning model development, and AI-driven solutions tailored to meet the specific needs of their clients. Datasparkemphasizes the importance of data-driven decision-making and works closely with businesses to implement strategies that enhance operational efficiency and improve outcomes. With a commitment to advancing the use of AI and data analytics, Dataspark aims to empower organizations to unlock the full potential of their data and stay competitive in a rapidly changing market.

Portfolio highlights

• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
• Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
• BetaGlue Technologies — BetaGlue Technologies engage in the research and offers anticancer products.

Portfolio highlights

• Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
• Neuromod Devices — Neuromod is the global medical device company that developed Lenire, the FDA Approved tinnitus treatment device.
• Endovascular Engineering — Endovascular Engineering is a medical technology company focused on developing and deploying advanced clot removal solutions for the treatment of venous thromboembolism. It specializes in thrombectomy technologies designed to improve clinical outcomes and procedural efficiency in minimally invasive vascular interventions. The company’s flagshipinnovation is the Hēlo™ Thrombectomy System, a catheter-based device that uses a combination of mechanical agitation and physician-controlled aspiration to remove blood clots. Its technology emphasizes features such as a self-expanding funnel design and dual-action functionality to enhance clot engagement and navigation through complex anatomies. Endovascular Engineering primarily serves healthcare providers, including interventional cardiologists and radiologists, supporting the treatment of conditions such as pulmonary embolism and deep vein thrombosis.

Portfolio highlights

• CareGlance — CareGlance is the provider of real-time monitoring systems based on SS-OCT technology. Fast, precise and developed for the industry!
• Rainbow Crops — Rainbow Crops is a next-generation Agtech company developing climate-resilient, high-performing crop varieties.
• Wearable Robotics — Wearable Robotics produces and develops wearable robotic systems and exoskeletons for rehabilitation, assistance and human-power augmentation.

Portfolio highlights

• Gility — Gility is a digital learning platform that collaborates with business schools and training institutions for an effective training offer. Established in 2022, it was supported by CDP Venture Capital and BPER Banca.
• Soplaya — Soplaya is a B2B food company connecting chefs and farmers to build a diverse, sustainable, and efficient food system.By providing data and transparency to an opaque supply chain, we help chefs to simplify purchases, get a wider selection of products and save money and farmers to increase their margins and get easy access to the market.We lovequality food as much as technology and automation. We are rebels: we love transparency and how the internet is capable of bringing the long tail to the market. We're excited about the fact that the restaurant supply chain hasn't basically changed since 40 years, and was technology reluctant for a long time, but restaurants necessities changed dramatically in the last 3 years.We’re becoming the standard layer for restaurant purchasing across Europe, by bringing transparency and simplicity in the procurement phase, increasing order frequency, promoting lean inventory and food waste reduction.
• Valvitalia SpA. — VALVITALIA is a leading group in the field of design, production, and overall supply of equipment and components intended for the petroleum, water, natural gas industries, and petrochemical industry as well as electrical power stations. The group works mainly with valves (core product), actuators, pipe fittings, flanges and systems for measuring,filtering, and regulating fluids and gases and with FireFighting systems. VALVITALIA was set up with the precise objective of becoming the leading Italian group able to offer such a wide range of products and to compete with the large American multinationals that have always dominated this field. This young company has extensive experience in the sector, thanks to its professional management and historical brands in the valve world that have been taken on by the Group, including: ROTOR, DELTA V.E., THEVIGNOT, VANADOUR, VITAS, TORMENE T.G.T. and TECNOFORGE. VALVITALIA has always included safety and respect for the environment and its employees among its priorities.

Portfolio highlights

• Clastix — Clastix is an enterprise Kubernetes infrastructure company, purpose-built to solve the operational challenges that emerge when Kubernetes runs at scale: cluster sprawl, fragile multi-tenancy, and the mounting cost of over-provisioned hardware and memory. The company's breakthrough is architectural. By combining hosted control planes with hard multi-tenancy, Clastix enables telcos, cloud providers, MSPs, and platform teams to run many isolated Kubernetes environments more efficiently, securely, and cost-effectively than traditional approaches allow. Clastix was founded by engineers who understood these pain points from direct experience running Kubernetes in production. That same commitment to quality engineering runs through everything the company builds – an approach shaped as much by Italian engineering tradition as by technical rigour. The result is infrastructure software that is functional, elegant, and highly scalable. The company's open source credentials are equally strong. Clastix donated Capsule to the Cloud Native Computing Foundation, co-founded Cloud Native Days Italy, and continues to evolve Kamaji – contributing not just code, but community and standards to the broader Kubernetes ecosystem. Clastix's platform is trusted by customers including NVIDIA and Mistral AI – organisations that operate some of the most demanding and innovation-intensive infrastructure environments in the world. Their confidence is a direct measure of what the platform can handle. Headquartered in Naples, Italy, with customers and partners across cloud, data centre, edge, and AI infrastructure globally, Clastix is where world-class engineering meets the real operational complexity of modern Kubernetes at scale.
• Tiledesk — Boost customer engagement with Tiledesk. Discover our conversational automation ready to use. Personalized experiences, improved conversion and retention.
• Comestai — Comestai focuses on digital and in-person treatment pathways for people with eating disorders. The company operates a hybrid care model that combines online consultations with psychologists, psychotherapists, psychiatrists, and clinical dietitians and access to physical clinical spaces. It offers virtual multidisciplinary therapy programs tailoredto individuals and families, with structured assessments and follow-up sessions. Comestai also develops corporate welfare programs that provide counseling groups, psychoeducational tools, and consultation modules for employees in partner organizations. Through its La Palestra di Animenta branch, it delivers structured professional training, including multi-module courses and continuing medical education pathways for clinicians treating eating disorders. Comestai additionally produces digital educational content such as the Hilde newsletter to support families and caregivers with practical information and clinical guidance about eating disorders.

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — BigProfiles is an Artificial Intelligence Platform designed for Utilities, Telcos, Banks, Insurance companies and Retails.Large companies such as Teleperformance, Eni, Unicef already have already successfully subscribed to our services.BigProfiles is the No-Code Artificial Intelligence Platform for sales and antichurn that predicts thelikelihood to purchase and churn of each customer in a CRM, before proceeding to contact him in a sales or retention campaign.
• Codemotion — Meetups, hackathons, training tours and conferences for developers and tech leaders.

Portfolio highlights

• Newcleo — newcleo is the clean and safe nuclear technology company. Privately funded and headquartered in London, UK, newcleo was launched in 2021 to be a disruptor in the field of nuclear energy. Its mission is to generate safe, clean and inexhaustible energy for the world, through a radically innovative combination of existing, accessible technologies.newcleo is building the next generation system with the goals to: (1) eliminate the need for geological repositories by using a fast neutron flux avoiding production of long life radioactive elements; (2) develop an Accelerator Driven System (ADS), based on the intrinsically safe coupling of a particle accelerator and a sub-critical reactor; (3) accelerate the development of new fuel cycles, including thorium, that provide economic, clean, safe and inexhaustible energy from nuclei and the opportunity to burn the long-lived nuclear waste produced by the old generation of nuclear reactors.With visionary co-founders, newcleo brings together a team of engineers with deep knowledge of nuclear energy with younger recruits with a fresh mindset, working to design an innovative micro Lead Fast Reactor with significant commercial applications, for example in shipping. newcleo wants to be the first step toward the evolution of its industry to become fully respectful of people and the environment. To develop a new, sustainable, and completely safe way of generating nuclear energy that will lead humanity to zero emissions, and to the mitigation of global warming.
• Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit

Portfolio highlights

• Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
• Dialybrid — Dialybrid provide product that include silkothane arteriovenous graft, SAG biomimetic nanostructure, and situ tissue engineering products. Their proprietary innovative technology, silkothane, is a hybrid material combining silk fibroin and polyurethane. Their aim is to develop a novel semi-degradable vascular access for hemodialysis.
• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit

Portfolio highlights

• HEU — HEU is a legaltech company that automates and manages legal documents and allows users to edit and share them.
• Tech4All — We support the study by using AI.
• GeneSys Bio — Antimicrobial Resistance (AMR) is a global health emergency projected to cause 10 million deaths annually by 2050. The crisis is fueled by slow, conventional diagnostics that take 3-5 days, forcing the empirical use of broad-spectrum antibiotics and accelerating the spread of superbugs.GeneSys Bio is commercialising a breakthrough solution: afully automated, sample-to-result molecular diagnostic platform that identifies infectious pathogens and their critical antibiotic resistance genes in under 30 minutes with >99% sensitivity and specificity. Our portable, laptop-sized device combines proprietary nucleic acid amplification with an AI-driven engine to deliver clear, actionable results directly to clinicians, veterinarians, and public health officials.Our platform is a modular "One Health" solution, adaptable via disease-specific kits for human, veterinary, and environmental applications. We are entering the market with a diagnostic for Urinary Tract Infections (UTIs), a condition affecting over 500 million people annually and a primary driver of antibiotic misuse. By enabling targeted therapy at the first patient encounter, our platform is set to reduce treatment costs by up to 13%, cut follow-up visits, and decrease mortality from complicated infections by 50%.GeneSys Bio is positioned to capture a significant share of this market by bridging the critical gap between speed, laboratory-grade accuracy, and accessibility. We are not just creating a device; we are building the future of decentralized infectious disease diagnostics to safeguard global health for generations to come

Portfolio highlights

• Relicta — Relicta solution is a water-soluble bioplastic material obtained from fish processing waste and suitable for packaging solutions.
• OhmSpace — OhmSpace provides the satellite market with reliable resistojets.
• LOTO Biotech — LOTO Biotech is a biotechnology platform focused on supporting the development of treatments for rare diseases, particularly those caused by dominant negative genetic mutations.

Portfolio highlights

• MMI — The future of Microsurgery: microinstruments that expand the possibilities of surgical interventions. Wristed robotic microinstruments for unprecedented results in microsurgery.
• Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
• RougeTx — RougeTx is a Netherlands-based biotech developing first-in-class small-molecule therapies for vascular diseases caused by pericyte dysfunction. Its lead candidate, RTX-001, targets hereditary haemorrhagic telangiectasia (HHT), an inherited disorder involving fragile blood vessels and recurrent bleeding.

Portfolio highlights

• Fazland — Fazland is an innovative web and mobile platform developed by the Italian startup Midnight Call Srl. The platform enables private clients to compare offers for home services and it helps efficient tradesmen to get in touch with potential customers in an easy and smart way. Midnight Call Srl was founded in October 2011 in Reggio Emilia (Italy).Following an initial phase of R&D, the product has become commercially available in March 2013.Following a very encouraging first year of operations, the company recieved a seed investment from the Italian venture capital fund RedSeed Ventures and some Angel Investors in July 2014. Through continuous product improvements and a solid commercial approach, the company has managed to build a solid position in the Italian market and launch pilot tests in few European cities.
• Passpack — Users can make and store passwords in a single, organized list, then access them from anywhere leaving no traces behind on the computer. Secure collaboration features allow users to make, send, share or provision passwords to colleagues, clients and partners -- a secure alternative to spreadsheets in the workplace. Managed via a central onlinerepository.Passpack is a free, professional tool. Optional premium upgrades are available for the micro-small business sector.
• GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.

Portfolio highlights

• iwoca — Iwoca provides financing to businesses for various purposes, including bridging short-term cashflow gaps and investing in stock opportunities. It services retailers, restaurants, hotels, and other businesses. It offers flexible repayment options from 1 day to 24 months, with no penalties for early repayment. Iwoca helps businesses manage cash flowgaps and invest in growth opportunities, enhancing their financial capabilities.
• Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
• Straiker — Security for agentic AI applications built from the ground up with fine-tuned models to protect and secure every layer of your agentic AI stack.

Portfolio highlights

• Verado — Verado is a global technology platform designed to empower everyone to instantly monetize their belongings. Whether selling an old laptop or unlocking cash by collateralizing valuables for a loan, our technology is crafted to enable consumers to do so with unprecedented ease. Snap a picture of your electronics, valuables, apparel or otherbelongings, get an instant appraisal through our real time valuation engine, and receive a direct payout to your bank account immediately. We are a deep technology company, envisioning a world where products’ lifecycle is lengthened and the ecological burden of trashing minimised. What exists currently is falling short of the experience modern consumers expect. They value convenience, comfort and speed, and don’t deem existing selling channels even marginally satisfactory. They are tired of the tedious paper-work, negotiating with uncommitted buyers through outdated messaging systems, managing the logistics, and the time-consuming nature of the process. Through our innovative solutions, we are cutting down from days to seconds the time it takes to receive a valuation; and from weeks to hours, the time necessary to sell!Verado is changing the rules of the game - It’s simplicity, re-engineered. We believe selling should be as seamless as buying. Therefore, rather than accumulating unused products at home or worse letting them end up in a landfill forever - we enable individuals to monetize their unwanted things, free up valuable space in their home and reduce their need for borrowing whilst simultaneously minimizing their ecological footprint.
• BetaGlue Technologies — BetaGlue Technologies engage in the research and offers anticancer products.

Portfolio highlights

• qomodo — Qomodo: La piattaforma BNPL innovativa. Rate a tasso zero, approvazioni veloci, transazioni sicure. Rivoluzionaria nell'acquisto per aziende e consumatori.
• Serenis Health — Serenis Health provides video-based psychotherapy, coaching, and psychological support courses. It believes that the internet is critical to increasing access to mental health care. It makes use of data and digital tools to improve the efficacy of therapies. But, unlike other platforms, it is also a medical center, which means it is responsible forcourse quality and must meet the same standards as any polyclinic.
• AutoConnexa — Scopri AutoConnexa, l'assicurazione online per la tua auto che premia lo stile di guida. Con Drive Connexa, meglio guidi e meno paghi.

Portfolio highlights

• VENPA — Noleggio Piattaforme Aeree e Noleggio Macchine Movimento Terra. Scopri tutti i mezzi da cantiere Venpa!
• Tony Kart — Tony Kart is an automotive company specializing in designing and manufacturing chassis, OTK kart parts, and karting wears.
• LMA srl - Aerospace Technology — LMA provides high-precision mechanical processes for aeronautics and aerospace. It operates in precision mechanics for civil and military aeronautical, helicopter, and expanding aerospace sectors.

Portfolio highlights

• Impress — Impress – is European leading digital orthodontic DSO of new generationWe have a defensible model with the personal touch of an in-house orthodontist, true clinical expertise, and engaging directly with consumersImpress was founded in 2019 in Barcelona with the idea of combining the best of orthodontic tradition with the most innovativetechnology in the sector. From the very beginning the vision of the Impress founders was to introduce a different business model with a strong focus on medical experience and digitalization. The company is transforming the oral healthcare industry by developing its own chain of orthodontic clinics, which are characterized by their disruptive design and modern patient experience. The founders decided to build a medical company with the personal touch of in-house orthodontists, face-to-face care, and unique clinical expertise, where the proper implementation of business processes and digitalization are at the core.In less than 2 years, Impress has managed to position itself as the European leader in the orthodontic sector, has treated more than 22.000 smiles and already has a presence in more than 80 European cities. Its innovation and quality have earned it recognition from Sifted as one of the fastest growing HealthTech companies in Europe in 2020.
• Santander Brasil — Banco Santander in Brazil, its largest division in Latin America and one of the world's most important, accounting for 50%.
• Dandara Solar Power SAE — Dandara Solar Power SAE is a special purpose vehicle, established to develop a major renewable energy and storage project in Upper Egypt. The entity oversees the development and operational construction of a 500 MW solar PV plant integrated with a 100 MWh Battery Energy Storage System. All electricity generated by the company is bound to be sold to the industrial manufacturer Misr Aluminum Company under a long term, take or pay power purchase agreement.

Portfolio highlights

• Soource — Soource is a B2B Saas product that uses AI applications to help purchasing managers to discover the best market solutions through extensive global research and automated email negotiations with thousands of suppliers worldwide.
• Comestai — Comestai focuses on digital and in-person treatment pathways for people with eating disorders. The company operates a hybrid care model that combines online consultations with psychologists, psychotherapists, psychiatrists, and clinical dietitians and access to physical clinical spaces. It offers virtual multidisciplinary therapy programs tailoredto individuals and families, with structured assessments and follow-up sessions. Comestai also develops corporate welfare programs that provide counseling groups, psychoeducational tools, and consultation modules for employees in partner organizations. Through its La Palestra di Animenta branch, it delivers structured professional training, including multi-module courses and continuing medical education pathways for clinicians treating eating disorders. Comestai additionally produces digital educational content such as the Hilde newsletter to support families and caregivers with practical information and clinical guidance about eating disorders.
• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit

Portfolio highlights

• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...
• Recornea — Recornea is a developer of a corneal medical device to restore the physiological curvature of the cornea with clear and predictable clinical outcomes.
• Health Triage — Health Triage, crea nuove tecnologie per offrire modelli innovativi di diagnosi clinica, identificazione e cura delle malattie oncologiche.

Portfolio highlights

• GenEp — GenEp, Inc. is a pre-clinical stage biotechnology company based on intellectual property assets. GenEp creates therapies targeting mutations of sodium and other ion channels that cause rare genetic epilepsies and other treatment-resistant epilepsies.
• Kainova Therapeutics — Domain Therapeutics is a biopharmaceutical company focused on GPCR in immuno-oncology. Discover more than you think on our innovative cancer treatments tackling GPCR mediated-immunosuppression
• Navion Neurosciences — Navion Neurosciences is a preclinical-stage biotechnology company developing next-generation, precision sodium channel therapies for neurological diseases.

Portfolio highlights

• KLISBio — KLISBio is a clinical-stage regenerative medicine company focused on developing innovative technology platforms based entirely on natural silk fibroin. The company, headquartered in Milan, Italy, currently has several assets under development, such as vascular graft, bone graft substitutes, rotator cuff repair, drug release, and a first-in-humanstudy on nerve repair that is ongoing at the University of Zurich, Switzerland
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• CityFibre — CityFibre is a brand new full fibre network built for the data age. Never worry about speed or reliability again. Connect your home and business today.
• Power Dot — Powerdot offers electric vehicle charging solutions in convenient locations across six European countries.
• Origis Energy — Origis Energy is powering the solar revolution with solar power and energy storage projects for utility, corporate and public sector energy clients.

Portfolio highlights

• Gardin — We believe in a world in which everyone has the right to access high quality, nutritious food that is good for you and for our planet. Our environmental issues are real, something, somewhere needs to change. Gardin promises to create the step-change required by deploying its technology.
• NoTraffic — NoTraffic has developed the first AI-powered traffic signal platform that connects road...
• Stellar — At Stellar we bring perfect internet on the move to vehicles and passengers, leveraging the combined strength of cellular, wi-fi, and satellite networks, through AI and fully integrated solutions. We offer SaaS, data plans, and all-inclusive options for enterprise connectivity needs on the move.

Portfolio highlights

• SimpL — SimpL is an Italy-based AI sales-intelligence and prospecting platform for B2B sales teams. It researches target companies, identifies relevant buying signals, drafts personalised LinkedIn outreach, manages follow-ups, and helps generate qualified sales meetings.
• Computis — Computis is an AI company offering software solutions for electronic invoicing, bank reconciliation, tax estimation, and billing services.
• Helix Robotics — We are building the first commercial soft manipulator

Portfolio highlights

• Baluwo — Providing basic essentials has never been this easy. Sending money is not always the solution so we provide easy, fast & convenient ways to send prepaid electricity top-ups, mobile top-ups and basic food items to support your family back home in The Gambia, and very soon in Senegal and Nigeria.
• Freedome — Freedome is the leading marketplace for outdoor activities in Italy
• GenomeUp — Rome-based healthtech startup that offers an ecosystem of AI-powered solutions for genetic analysis and clinical decision support for diseases. GenomeUp's mission is to be a global reference platform to support clinical decision-making for hospitals, laboratories, research centers, and pharmaceuticals to accelerate diagnosis times, improvepatient care and provide knowledge for health prevention, all in less than 24h. Based on these assumptions, the founders decided to evolve the startup and transform it into a Italian Benefit Corporation following the purpose of common benefit by acting responsibly, sustainably and transparently towards stakeholders, people, communities, the territory and the environment.

Portfolio highlights

• Biorsaf — Biorsaf is an IT company that develops mobile apps and web control panels to assist companies to bring efficiency to their operations.
• Cosmico — We are the platform connecting digital talents with the most ambitious companies, using remote work.We have over 8,000 members and our talents have accelerated dozens of projects alongside big names like Accenture Song, Tangity, Frog, Fjord, Sketchin, EY but also aggressive start-ups like Scalapay, Gimme5, Flowe, Unguess.If you are a digitalprofessional: we offer you a community in which to grow your talent through experiences, networks and cosmic projects.If you are a company: we offer you access to a community of designers, developers and marketers from which to select the talents to accelerate your digital transformation projects. Whether you are a manager or a digital professional, Cosmico is here to help you find your space
• Agora Labs — Agora Labs is an Italian medical deep-tech enterprise that provides a secure, decentralized infrastructure for real-time health data sharing and privacy-preserving clinical research. The company solves the fundamental privacy and regulatory bottlenecks in healthcare, allowing researchers, life science corporations, and AI developers to collaborate without exposing sensitive patient information.

Portfolio highlights

• Evja — Evja supports growers in optimizing the management and monitoring of irrigation, nutrition and protection of their crops through the use of OPI, the most advanced system for precision agriculture .
• BionIT Labs — BionIT Labs is an Italian-U.S. company developing prosthetic and robotic technologies built around how humans move, perceive, and interact with the physical world.
• Planeat.eco — Planeat.eco is the site where you can plan your food shopping in a simple and economical way, starting from the recipes and receiving at home all the ingredients ready for preparation , weighed and divided into compostable containers. They offer their products online.

Portfolio highlights

• Palyon Medical — Palyon Medical Corporation is a medical device company developing technologies for the treatment of chronic pain, spasticity and other neurological diseases.
• Neuromod Devices — Neuromod is the global medical device company that developed Lenire, the FDA Approved tinnitus treatment device.
• Vivasure Medical — Pioneering the Future of Large-Bore Vessel Closure for Arterial and Venous Access. The first and only 100% bio-absorbable, sutureless patch..

Portfolio highlights

• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit
• Tubulis — Reimagining Antibody Drug Conjugates Tubulis generates uniquely matched protein-drug conjugates through the combination of novel proprietary technologies and disease-specific biologic insight. Our goal is to expand the therapeutic potential of antibody-drug conjugates (ADCs) by increasing design flexibility while overcoming constraints of toxicity, efficacy and indication. Tubulis will build new conjugates to fill its pipeline and
• Aeovian Pharmaceuticals — Aeovian is a San Francisco based biopharmaceutical company developing novel and highly selective therapeutics modulating mTORC1 pathway.

Portfolio highlights

• Busforfun — Shared and Green traveling to experience the world of fun#WeTheFun | Busforfun is a young mobility company traveling in a sustainable, safe and low-cost way across Europe. Busforfun vision is a green and shared mobility to experience the world of fun.#WeTheTech | Busforfun is a combination of high tech-startup, e-commerce-platform andtransportation company, Busforfun is going to establish European largest bus network for events in the short time. Thanks to a powerful search engine, business intelligence, an user-friendly booking system and an extensive route network, Busforfun offers travellers the opportunity to experience the world of fun with lower fares.#WeTheGreen | Our low-emission buses comply with the highest safety and environmental standards, so Busforfun offers a sustainable and convenient alternative to cars. With main partner Treedom, Busforfun plants new trees at any travel worldwide.Live Fun Experience in partnership – our concept for successBusforfun provides customers with great offers at lowest budget, through smart network planning, dynamic price management and an adaptive web engine.Busforfun platform is where the innovation and start-up spirit meet the experience and know-how of traditional bus companies and travel agencies.Incredible success can be attributed to the digitalization of old-fashioned bus travel industry: Busforfun has not suppliers or clients: but partners only!
• Easy Rain — Leading a new automotive era: our modular ecosystem of virtual sensors and active hardware makes cars and autonomous platforms truly safe in every condition.
• Faccin Group — Faccin Group leads in manufacturing top tier metal forming & bending machines. Operating as Faccin, Roundo & Boldrini, we offer unparalleled expertise.

Portfolio highlights

• C.NEXT — C.NEXT develops innovation projects for businesses and organizations by supporting the economy and territorial regeneration.
• Vivavoce — Vivavoce supports a team of neurologists, neuropsychologists, and physiotherapists, developing an innovative approach. They offer treatment for stuttering, for which they offer a rehabilitation path based on the MRM-S method. They treat people suffering from stuttering, problems related to voice and language, and the psychological andemotional-behavioral sphere.
• Way Experience — Way Experience operates in all the entertainment B2C sectors, using augmented and virtual reality technology. They also work in the B2B area by applying their technologies for customized consultancy projects in the following sectors: design, fashion, medical, events, and training.

Portfolio highlights

• Cyllene Therapeutics — EG 427 is a French biotechnology company that pioneers a new approach in gene therapy called pinpoint gene therapy.
• Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
• HighLife — HighLife is driven by a mission to deliver innovative treatment options to patients suffering from heart valve diseases.

Portfolio highlights

• D-EYE — D-EYE's technology enables healthcare professionals all over the world to quickly screen for problems, photograph them and then distribute them digitally via various secure wireless solutions. They design and manufacture diagnostic instruments.
• GrowthLever.io — GrowthLever.io is a B2B sales development company that offers full-service outreach providers. The company books meetings for recruiting, marketing, and prof. service companies. It was founded in 2019 and based in Chicago, Illinois.

Portfolio highlights

• Leaf Space — Leaf Space offers a global network of ground stations, providing seamless, cost-effective satellite communication with scalable solutions for all mission sizes.
• Yope — Salo is a discussion platform that erases the borders for people with diverse opinions to let anyone speak up and be heard.
• CyberRidge — CyberRidge is a deep-tech cybersecurity firm that develops photonic encryption to protect data privacy.

Portfolio highlights

• Id.Eight — D.EIGHT is a brand of eco-friendly sneakers produced from food industry waste and recycled material.
• AmaliaCare — AmaliaCare is a socially conscious company that gives a new perspective to the world of aged care. AmaliaCare are the premier digital employment agency, specializing in profiling the ideal domestic workers using cutting-edge technology for families seeking dependable assistance for loved ones who are no longer self-sufficient.
• HARG - Healthy Aging Research Group — HARG researches, develops, and markets dehydrated food preparations with modified textures. The company ensures nutritional principles are the same or even enhanced when compared to those of a typical meal by using only natural ingredients. The R&D activity done in collaboration with the University of Genoa ensures scientific efficacy. HARGseeks to enhance the health and wellbeing of those who struggle with swallowing.

Portfolio highlights

• 4MDG — 4MDG creates a master data governance software suite that aims to provide management, sanitization, and enrichment of all kinds of information. Their platform focuses on registry cleaning, data governance, data analysis, integrated solutions, and differentiated products, providing businesses with real-time data, automated processes, data integrity,risk reduction, and improved operational efficiency in master data management.
• Dubit — Choose your path in the Metaverse.
• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...

Portfolio highlights

• ScubaTx — ScubaTx is a breakthrough organ preservation device organ transplant. The ScubaTx device will leverage world-leading expertise in software design to commercialise a proven but unexploited organ preservation technique, Persufflation. ScubaTx will offer healthcare providers significant net savings, an
• Infex Therapeutics — Infex Therapeutics acquire, develop and license drugs to treat pandemic infections.
• Monument Therapeutics — Monument Therapeutics is a biotechnology company intended to develop drugs to treat serious diseases of the central nervous system.

Portfolio highlights

• GenomeUp — Rome-based healthtech startup that offers an ecosystem of AI-powered solutions for genetic analysis and clinical decision support for diseases. GenomeUp's mission is to be a global reference platform to support clinical decision-making for hospitals, laboratories, research centers, and pharmaceuticals to accelerate diagnosis times, improvepatient care and provide knowledge for health prevention, all in less than 24h. Based on these assumptions, the founders decided to evolve the startup and transform it into a Italian Benefit Corporation following the purpose of common benefit by acting responsibly, sustainably and transparently towards stakeholders, people, communities, the territory and the environment.

Portfolio highlights

• GenomeUp — Rome-based healthtech startup that offers an ecosystem of AI-powered solutions for genetic analysis and clinical decision support for diseases. GenomeUp's mission is to be a global reference platform to support clinical decision-making for hospitals, laboratories, research centers, and pharmaceuticals to accelerate diagnosis times, improvepatient care and provide knowledge for health prevention, all in less than 24h. Based on these assumptions, the founders decided to evolve the startup and transform it into a Italian Benefit Corporation following the purpose of common benefit by acting responsibly, sustainably and transparently towards stakeholders, people, communities, the territory and the environment.

Portfolio highlights

• Ozon — leading e-commerce platform in Russia, first russian marketplace
• Personio — Personio is the Intelligent HR platform for companies from 10-5,000 employees, powering over 1 million people worldwide. Book your free demo today.
• Culture Amp — Culture Amp was founded as a result of its members' first hand experiences with the challenge that fast growing organizations face when their core business expands faster than its people can adapt. With years of experience in enterprise organizations, CultureAmp's team has taken more than a walk in your shoes–they've been running inthem. They look to seize an opportunity for a new type of technology- technology that amplifies learning and drives culture, instead of hindering it.

Portfolio highlights

• Chiasma — We are a commercial stage pharmaceutical company focused on developing and delivering innovative new treatments that help improve the lives of people with rare diseases.
• Syndax Pharmaceuticals — Syndax Pharmaceuticals is a clinical-stage pharmaceutical company that focuses on an HDAC inhibitor for solid tumors and hematological tumors. It offers therapies to treat solid tumors and lung, breast, and hematological cancer. The company is developing axatilimab, a monoclonal antibody that blocks the colony-stimulating factor 1 (CSF-1) receptor,in development for chronic Graft versus Host Disease, and entinostat, a class I HDAC inhibitor.Syndax Pharmaceuticals pipeline includes and SNDX-5613, a highly selective inhibitor of the Menin–MLL binding interaction, in development for the treatment of patients with MLLr and NPM1 acute leukemias.
• Portola Pharmaceuticals — As Alexion, AstraZeneca Rare Disease, we are delivering life-changing therapies to people living with rare diseases.

Portfolio highlights

• Convoy — Using technology and automation, the Convoy Platform seamlessly connects carriers with shipments from brokers across the nation.
• FinCompare - Smarter Business Finance — FinCompare was founded by Stephan Heller and is a fintech startup that helps businesses to find, compare, and close the financing solutions. Via the online platform, companies can access a wide range of financing options. They can independently compare offers from well-known banks, fintechs, and alternative financial services providers in Germanyand close the financing. The company also offers a convenient one-stop destination for all financing questions relating to the company.FinCompare financing solutions including corporate loan, factoring, company leasing/hire purchase, warehouse financing, fine trading/purchase financing, and mezzanine capital. It simplifies the financing process with its digital application process and can thus provide your company financing. The company allows SMEs to receive and compare various offers for loans.FinCompare was founded in October 2016 by Stephan Heller and is headquartered in Berlin, Germany.
• Finom — Finom is an online payment solution for entrepreneurs that makes it easy to open a business account and securely manage their finances.

Portfolio highlights

• Banxware — Banxware provides the technology and the funds for business financing of any kind: fully embedded in your platform or as an affiliate solution - all managed by Banxware
• DevTwo S.p.A. — DevTwo S.p.A. is a special purpose vehicle belonging to Gruppo Barletta,
• Gruppo Barletta — Gruppo Barletta specializes in real estate, hospitality, and venture capital for the construction sector.

Portfolio highlights

• AFYREN — AFYREN develop innovation in biotechnologies for the valorization of non-food biomass and in respect of the environment.
• Naturbeads — Naturbeads creates biodegradable, sustainable and cost competitive cellulose microbeads to replace currently used microplastics.
• USIL Therapeutics — USIL Therapeutics is a biotechnology company focused on radiological preparedness. They develop dual-use medical countermeasures designed to protect populations and mission-critical personnel from ionizing radiation in defense, civilian, and space environments.

Portfolio highlights

• Agatha — Agatha is a provider of strategic software solutions to the health care and life sciences industry. It is dedicated to helping hospitals, biotechnology, pharmaceutical, contract research organizations, and medical device firms optimize the management of their quality and clinical documentation and processes.
• PlasmidFactory — PlasmidFactory is the leading contract manufacturer and service provider for plasmid DNA and minicircle DNA, custom DNA, In-Stock DNA for AAV and clinical application
• Ceva Santé Animale — Ceva Sante Animale S.A. engages in the research, development, production, and marketing of pharmaceutical products and vaccines for companion and farm animals. They work with welfare and social programmes around the world to bring this vision to life – anywhere their products and know-how can make a difference and with all kinds of partners. FromUganda, working with small-scale livestock owners and vets to stop sleeping sickness in its tracks, to the UK and USA, where they supply the biggest animal welfare charities with Adaptil® collars to help re-home shelter dogs.

Portfolio highlights

• Medicud — Medicud develops a device for treating wounds with negative pressure dressing.

Portfolio highlights

• Lever Bio — Lever Bio aims to translate groundbreaking discoveries in immuno-oncology into next-generation cancer immunotherapies.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.
• Haptena Therapeutics — Haptena Therapeutics develops next-generation immunotherapies for oncogene-driven cancers, integrating precision oncology and immune engineering. Our research focuses on KRAS-mutant tumors to deliver more effective and durable treatment options.

Portfolio highlights

• Coave Therapeutics — Coave Therapeutics is active in the field of gene therapies in rare ocular and CNS (Central Nervous System) diseases.
• Perfuze — Perfuze was founded in 2018 by Wayne Allen and Liam Mullins. Perfuze is located within Galway City in the West of Ireland. The founders have over 30 years combined medtech experience within start-up and large corporations.Perfuze is developing innovative medical technology to treat acute ischemic stroke.Perfuze is developing innovative cathetertechnology to treat acute ischemic stroke. Their technology is intended to provide superior clinical outcomes in shorter procedural times; resulting in safe, cost-effective therapy. Perfuze was founded in 2018 by Wayne Allen and Liam Mullins. The founders have over 30 years combined medtech experience within start-up and large corporations. Perfuze is currently located in the Business Innovation Centre on the campus of the National University of Ireland, Galway, and is in the process of relocating to the IDA Business Park in Dangan, Galway.
• Azafaros — Azafaros aims at developing therapeutic agents for the treatment of rare metabolic disorders such as lysosomal storage disorders through oral administration of azasugar compounds. These novel, very promising agents were discovered by Professor Hans Aerts at Leiden University and Amsterdam UMC and are exclusively licensed to Azafaros.