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Top 50 Medical VC (Venture Capital) Funds in Italy in February 2025

Last updated: Feb 2025 A list of 50 VC (Venture Capital) funds that invest in Medical startups based in Italy. We rank investors based on the number of investments they made in Medical companies from Italy. We update this investor list every month.

Top 50 Medical VC (Venture Capital) Funds in Italy in February 2025

Investor	Medical Italy investments
Italian Angels for Growth	8
CDP Venture Capital	7
Innogest Capital	6
Panakes Partners	4
Invitalia Ventures	4
LIFTT	4
Vertis	3
INGENIUM Emilia Romagna	3
Indaco Venture Partners	3
3B Future Health Fund	2
Equiter	2
Lumen Ventures	2
Lazio Innova	2
Principia SGR	2
Neva SGR	2
Index Ventures	1
MVM Life Science Partners	1
Rancilio Cube	1
Angelini Ventures	1
Spindial Group	1
Kairos Partners	1
V-Bio Ventures	1
Andera Partners	1
Sviluppo Imprese Centro Italia	1
Padda Health	1
MPM Capital	1
Launch Tennessee	1
Fincarl	1
P101	1
Alchimia Investments	1
GM&C Life Sciences Fund	1
Toscana Next Fund	1
Fondazione Cottino	1
CDP Equity	1
Fondazione Golinelli	1
a\|impact	1
Evotec	1
Metaventures	1
Rearden Capital Management LLC	1
RedSeed Ventures	1
VI Partners	1
Scientifica Venture Capital	1
Seroba Life Sciences	1
Exceptional Ventures	1
RoboIT	1
CRB Inverbío	1
Si14	1
Finalca	1
Romed	1
MiMiT Women's Enterprise Fund	1

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Investor list

IAG is an angel investor network that offers access to its affiliates to early-stage venture opportunities. Its members to date have deployed over 22 million Euros to support 41 startups in the series seed/series A stage in many verticals, among which: Medtech, SAAS, e-commerce, Fintech, and high tech at large. Every investment opportunityat IAG is vetted by a professional team together with expert members of the group. Once invested, the company receives the support of up to two Investment champions, who bring their expertise to the table and help them succeed.

Investment focus

Software, E-Commerce, Health Care
Seed, Angel, Series A
Italy, United States, United Kingdom

Portfolio highlights

ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.
Rubedo Life Sciences — Rubedo Life Sciences is the Premier Longevity Company. Rubedo discovers and develops medicines to keep you biologically young.
Restorative Neurotechnologies — Siamo un'azienda di dispositivi medicali certificati per la riabilitazione cognitiva ed il trattamento di disturbi cognitivi post ictus.

CDP Venture Capital Sgr - National Innovation Fund aims to make venture capital a cornerstone of the country's economic development and innovation, creating the conditions for an overall and sustainable growth of the venture capital ecosystem.

Investment focus

Software, Information Technology, Health Care
Seed, Series A, Funding Round
Italy, United States, Germany

Portfolio highlights

Ekore — Miglioriamo la gestione degli edifici ottimizzando i consumi e la gestione delle manutenzioni tramite il concetto di Digital Twin.
Spoki — Spoki helps businesses increase sales thanks to WhatsApp.Emails are no more a valid communication channel between businesses and customers. Spoki helps businesses engage their customers using WhatsApp during the whole customer journey: marketing, sales and customer support.Spoki is a WhatsApp conversational platform that allows you to: - sendbulk marketing messages to thousands customers with a click - integrate WhatsApp with: - Ecommerce to notify abandoned cart, tracking number and order status - Marketing Automation Tools or CRM to add it to sales funnels - Social and Digital ADS to catch users in the exact moment expressing their interest in products and services - create automations and chatbots, for customer support or whatever you can think ofIf you are confident with the results you get today with emails, you'll be amazed at what you can achieve with Spoki.
Marine Energy Space Control — MESPAC is a service suite that delivers to the offshore wind and ocean energy industries highly accurate, continuous, and spatially-refined wind, wave, and other metocean information for project development, financing, and operation.

We are investors in companies that make the difference. We partner with hard-working entrepreneurial visionaries

Investment focus

Health Care, Medical, Medical Device
Funding Round, Series A, Series B
Italy, United States, Spain

Portfolio highlights

GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
BetaGlue Technologies — BetaGlue Therapeutics is a life sciences company that delivers radiotherapy from within. Introducing Yntradose, our proprietary product.

Panakes Partners is a venture capital investor that finances in medical companies, startups, and high growth SMEs in Europe and Israel. Advantages of the firm are broad network of business contacts and corporate relations, domain expertise, proactive portfolio management, and relationship with selected industrial partners. Investments of thecompany focus on medical devices, diagnostics, biotech for in-vitro diagnostics, IT healthcare, and medical services.Panakes Partners is an Italy-based company that was founded in 2015 by Alessio Beverina, Fabrizio Landi, and Diana Saraceni.

Investment focus

Health Care, Biotechnology, Medical
Series A, Series B, Seed
Italy, Ireland, Switzerland

Portfolio highlights

Alesi Surgical — Developer of Ultravision, the revolutionary system that clears surgical smoke from the visual field during laparoscopic surgery
Lymphatica Medtech — Lymphatica Medtech is a medical device development company developing a minimally invasive solution for chronic lymphedema.Lymphedema is the chronic swelling that generally occurs in the arms or the legs.Lymphedema is most commonly caused by the removal of or the damage to the lymph nodes as a part of cancer treatment. It results from ablockage in the lymphatic system, which is part of the immune system. The blockage prevents the lymphatic system from draining excess fluids, and the fluid buildup leads to swelling, infections, and pain.Unfortunately, there is no cure for lymphedema. It can be managed with early diagnosis and diligent care of the affected limb, through daily compression, bandages, and manual drainage sessions. From the moment of the diagnosis, the life of lymphedema patients changes forever.Cancer and cancer-related interventions (i.e. surgery, radiotherapy) are frequent causes of lymphedema occurring both in the upper and lower limbs. Breast cancer survivors are at high risk for developing lymphedema, as well as patients treated for melanoma, pelvic and head and neck cancer or other cancer treatments that require lymph node dissection. Physical trauma can also result in lymphedema, a major cause of lymphatic disease among wounded veterans.Lymphedema is associated with significantly impaired quality of life, skin changes, increased risk of infection and in rare cases lymphedema itself may undergo malignant transformation.Lymphatica offers a permanent solution that will allow patients to regain their normal lifestyle.
CorFlow Therapeutics AG — CorFlow Therapeutics is a medtech startup that develops proprietary technologies for diagnosis and treatment of microvascular obstructions in heart attack patients. The CorFlow technologies enable interventional cardiologists to diagnose and treat MVO in severe heart attack patients thereby potentially reducing the short- and long-term complicationrates in these patients.

Invitalia Ventures SGR manages the “Italia Venture Fund I”, a 87€/Ml sized co-investment fund that invests in early stage operations in Italy. They co-invest up to a maximum of 70% in round A (€ 0.5ML - € 1.5ML) in high growth sectors. Invitalia Ventures, with its network of co-investors not only provides risk capital, but also know-how and anetwork for business development. Main LPs includes the Ministery of Economic Development, the European Investment Bank, Cisco Group, the Sardinian Banking Foundation and Metec Group.They are looking for visionary entrepreneurs who share their passion for innovation. Growth is their mission!!For more information please contact us at info@invitaliaventures.it or visit our website: www.invitaliaventures.it

Investment focus

Software, Medical, Health Care
Series A, Funding Round, Seed
Italy, United States, United Kingdom

Portfolio highlights

Ecomate — The ESG Rating platform for every company
BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

A not-only-profit operating investment company, eager to create a bridge between innovative ideas, territory and capital.

Investment focus

Biotechnology, Software, Information Technology
Seed, Funding Round, Series A
Italy, United Kingdom, France

Portfolio highlights

Mediaire — mediaire supports radiologists with AI-based tools for MRI reporting. This enables them to make a more accurate and objective assessment even faster.
MicroLub — MicroLub produces a fat replacement for lower-calorie plant-based diets. It is cutting-edge innovation to the next generation of protein technology, creating exclusive ingredient solutions that significantly minimize molecular friction.
Composite Research — CoRe Research is an start-up, aimed at the study of new product and process solutions in the field of composite materials.

Vertis is a dynamic and independent investment management company authorised by Bank of Italy. It manages five closed-end funds for qualified investors by participating in research projects, spin-offs, startups and PMI and deals with the investments of the innovative Made in Italy.

Investment focus

Software, E-Commerce, Computer
Seed, Funding Round, Series A
Italy, United States

Portfolio highlights

Aindo — Unlock the full potential of your data. The power of synthetic data integrated in a comprehensive Data Platform.
Radical Storage — Find your closest luggage storage and enjoy your journey until the very end!
Starting Finance — Starting Finance is a financial education platform intended to provide financial literacy to its users. The company's platform provides education and information about finance and publishes informative articles on important events in the fields of economics, finance, and politics, enabling users to improve their knowledge regarding finance andthe management of their capital.

INGENIUM Emilia Romagna was started with EUR 5.30 million by the Emilia Romagna region and EUR 1.7 million from fund managers. Managed by META Investment, the nine-year fund operated through the temporary acquisition of minority stakes in high-opportunity technological companies. It is now fully invested.

Investment focus

Medical, Health Care, Privacy
Seed, Angel, Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.
GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Angiodroid — Angiodroid srl, a medical technology company, focuses on hemodynamics, vascular surgery, and interventional radiology. It offers an automatic injection system for carbon dioxide angiography. Its products include carbon dioxide injector that is used as a contrast medium for pheriperal interventional angiography; and a single use kit, which iscomposed of French catheters and a custom connection line. The company is based in San Lazzaro di Savena, Italy.

VENTURE We invest across all sectors with specific focus on technology and digital The largest independent more About Us Portfolio [...]

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
Italy, Switzerland, United States

Portfolio highlights

D-Orbit — End-to-end services for the New Space industry, including platform engineering, launch and deployment, and decommissioning.
MicThera — MicThera focuses on developing microbial-derived therapeutics to provide effective treatments for prostate cancer patients, aiming to find effective solutions for medical companies.
Genespire — Genespire is a biotechnology company focused on the development of transformative gene therapies for patients affected by genetic diseases, particularly primary immunodeficiencies and inherited metabolic diseases.

Helsinn Investment Fund S.A. is a Luxembourg fund focused on early-stage investments in areas of high unmet patient need.

Investment focus

Biotechnology, Therapeutics, Medical
Series B, Series A, Funding Round
United States, Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
Fore Biotherapeutics — We are a precision oncology company pioneering the development of cancer therapies guided by our proprietary functional genomics.
On Target Laboratories — ON TARGET LABORATORIES discovers and develops fluorescent markers to target and illuminate cancer during surgery so it can be removed more completely.

Equiter seleziona, realizza e gestisce investimenti infrastrutturali in capitale di rischio finalizzati allo sviluppo socio-economico del territorio.

Investment focus

Medical, Health Care, Information Technology
Seed, Series B, Convertible Note
Italy

Portfolio highlights

AWorld — AWorld is The Sustainability Platform and Mobile App chosen by the United Nations to support the ActNow Campaign.
Medics — 3D anatomical modeling per la pianificazione pre-operatoria e il supporto intra-operatorio delle chirurgie complesse.
BionIT Labs — We apply IT to Bionics in order to Turn disabilities into New Possibilities

Lumen Ventures is a venture capital firm that focuses on seed investments, early-stage investments, and private equity.

Investment focus

B2B, E-Commerce, Food and Beverage
Seed, Pre-Seed, Series A
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.
Insoore — Insoore is a platform that helps insurance companies to improve the claims management process, thanks to on-demand photographic inspections and damage estimates provided by a community of experts.
Carol — Carol is a tech-enabled healthcare provider delivering membership-based primary care services, on a mission to make high-quality healthcare accessible and affordable for everyone. To achieve this goal, Carol leverages a highly scalable technology, combined with high quality clinical operations and a salaried provider model.

Lazio Innova is a venture capital firm with its headquarters in Rome in Italy. The firm provides services in areas such as credit support and guarantees, interventions in risk capital, internationalization services, promotion of business networks and services for the creation and enterprise development.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Pre-Seed, Grant
Italy, United Kingdom

Portfolio highlights

Joinrs — We developed an artificial intelligence model able to read job offers for you and show you the ones that best match your profile.
Medicud — Medicud develops a device for treating wounds with negative pressure dressing.
Ticketoo — Ticketoo: compra e vendi biglietti fan-to-fan in modo sicuro

Principia is an Italian Venture Capital firm with over Eur 80M under management. Currently Principia has two funds investing in digital start ups and expansion capital opportunities and in particular cases, we invest also in seed opportunities.

Investment focus

Health Care, Biotechnology, Software
Funding Round, Series A, Seed
Italy, United States, United Kingdom

Portfolio highlights

KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Neva SGR, part of the Intesa Sanpaolo Group and wholly owned by the Intesa Sanpaolo Innovation Center, plans and manages investment funds for professional investors interested in seizing diversification and high-yield opportunities offered by Venture Capital investments. Neva SGR can count on Intesa Sanpaolo Innovation Center’s and Intesa SanpaoloGroup’s strength, financial resources, know-how and network of relationships, a unique source of value on the market. Neva SGR is the perfect blend of strength, reputation and stability of the Intesa Sanpaolo Group and the best practices of international venture capital firms. Neva SGR aims to boost the Italian economy through new technologies and to be market maker of the VC asset class of venture capital in Italy.

Investment focus

Software, FinTech, Financial Services
Series A, Series B, Funding Round
Italy, Israel, United States

Portfolio highlights

Casavo — Want to sell your house fast? Fill out the online form and receive a free home value estimate and real estate prices from Casavo!
NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
BetaGlue Technologies — BetaGlue Therapeutics is a life sciences company that delivers radiotherapy from within. Introducing Yntradose, our proprietary product.

Index Ventures is an international venture capital firm with dual headquarters in San Francisco and London, investing in technology-enabled companies with a focus on e-commerce, fintech, mobility, gaming, infrastructure/AI, and security.

Investment focus

Software, E-Commerce, Internet
Series A, Series B, Seed
United States, United Kingdom, France

Portfolio highlights

Allara — Allara is your all-in-one virtual care team for hormonal, metabolic & gynecological conditions such as PCOS and Endometriosis.
nexos.ai — Introducing nexos.ai — a powerful model gateway that delivers game-changing AI solutions. With advanced automation and intelligent decision making, nexos.ai helps simplify operations, boost productivity, and accelerate business growth.
Instabase — Instabase combines the latest AI breakthroughs with industry expertise to create real business value for your business.

MVM invests in innovative healthcare companies. Our active portfolio companies are transforming the delivery of healthcare by enabling higher quality, cost-effective care in large, global markets.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Series B, Series C
United States, United Kingdom, Switzerland

Portfolio highlights

Ossio — OSSIO is an orthopedic fixation company committed to transforming the orthopedic experience for patients, physicians, and payors. Their vision is to provide the first credible replacement to metal implants in the $10B+ orthopedic fixation market (screws, pins, plates) with an Intelligent Bone Regeneration Technology. OSSIOfiber represents abreakthrough material platform for orthopedic and podiatric surgeons who seek a more biologically friendly way to restore patient stability and mobility with nothing permanent left behind.Founded in 2014, OSSIO began as the culmination of years of biomechanical research and a vision for the possibility of better bone healing. The technological basis of OSSIOfiber™ was developed and would lay the groundwork for ushering in a new breakthrough category of non-permanent fixation, “Bio-Integratives” hardware that has both desired strength AND bio-friendliness. Hardware that has the mechanical strength for easy insertion and secure fixation, while enabling the body to regrow bone, incorporating and replacing the implant (without the adverse inflammation and weakness often seen in “bio-resorbables and other “bio-composites”), has remained elusive to the industry until now.
Icotec — Icotec develops and produces carbon fiber reinforced plastic implants for spine surgeries and accident treatments.
Nalu Medical — Nalu Medical is an early-stage company that develops a range of medical devices. Their vision to modernize and improve the technology in medical devices, thus improving the lives of people.The Nalu neurostimulation system is a battery-free, micro-implantable pulse generator (iPG) currently cleared by the FDA for both Spinal Cord Stimulation (SCS)and Peripheral Nerve Stimulation (PNS) for mitigating chronic pain. The company was founded in 2014 and is based in Carlsbad, California.

Cube is the investment office founded by Rancilio family

Investment focus

E-Commerce, Software, Financial Services
Seed, Series A, Series B
United States, Italy, Germany

Portfolio highlights

Convoy — Using technology and automation, the Convoy Platform seamlessly connects carriers with shipments from brokers across the nation.
FinCompare - Smarter Business Finance — FinCompare was founded by Stephan Heller and is a fintech startup that helps businesses to find, compare, and close the financing solutions. Via the online platform, companies can access a wide range of financing options. They can independently compare offers from well-known banks, fintechs, and alternative financial services providers in Germanyand close the financing. The company also offers a convenient one-stop destination for all financing questions relating to the company.FinCompare financing solutions including corporate loan, factoring, company leasing/hire purchase, warehouse financing, fine trading/purchase financing, and mezzanine capital. It simplifies the financing process with its digital application process and can thus provide your company financing. The company allows SMEs to receive and compare various offers for loans.FinCompare was founded in October 2016 by Stephan Heller and is headquartered in Berlin, Germany.
Finom — Finom is an online payment solution for entrepreneurs that makes it easy to open a business account and securely manage their finances.

Angelini Ventures is an investment firm.

Investment focus

Health Care, Therapeutics, Biotechnology
Series A, Series C, Seed
United States, Italy, Belgium

Portfolio highlights

Nobi — Fall detection for the elderly at your home or in a residential care center with the smart Nobi lamp. Nobi ensures that you can be helped quickly.
Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit
Neumirna Therapeutics — Founded in 2020, NEUmiRNA focuses on achieving transformative disease modification for neurological conditions.

Spindial Group

Investment focus

Medical, Health Care, Biotechnology
Funding Round
Italy

Portfolio highlights

Glomeria Therapeutics — Glomeria Therapeutics researches, develops, and markets new medical devices for the treatment of serious diseases in the nephrological area. It offers DesmoPD, peritoneal dialysis connection system; SmartPD, an automated management device for peritoneal dialysis solutions to be instilled in peritoneum; and solutions for peritoneal dialysis.Andrea Zanella founded Glomeria Therapeutics in 2010. Its headquarters is in Chieti in Italy.

Kairos Partners SGR is a independent Italian asset management company.

Investment focus

Financial Services, FinTech, Fashion
Seed, Series A, Funding Round
Italy

Portfolio highlights

Viceversa — Viceversa provides capital to European digital businesses to support companies in sustainable and ethical growth. The company was founded in 2021 and has locations in Milan and Dublin.
Hercle — Hercle is a FinTech company that develops low-latency technology that offers end-to-end prime-brokerage solutions and trading algorithms to institutional investors who are interested in gaining exposure to crypto-assets.
Underscore District — Underscore District unlocks the potential of Made in Italy fashion brands through the power of technology and data analytics.

V-Bio Ventures is an independent venture capital firm specialized in building and financing young, innovative life science companies. The fund invests throughout Europe in start-up and early-stage companies with high growth potential focusing on technologies that provide transformational improvements in the biotech, pharmaceutical and agriculturalsectors.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Seed
Belgium, France, United Kingdom

Portfolio highlights

ATB Therapeutics — ATB Therapeutics is a biopharmaceutical company that provides novel therapeutic solutions and treatments for cancer patients.
Confo Therapeutics — Confo Therapeutics is a drug discovery company building internal drug discovery programs on GPCRs addressing unmet medical need. Confo Therapeutics employs its proprietary CONFO® technology to lock inherent unstable functional conformations of GPCRs as a superior starting point for drug discovery. CONFO® body-stabilized active state conformationsof these receptors disclose previously inaccessible structural features empowering the discovery of novel agonists for better therapeutic intervention.
Augustine Therapeutics — Augustine, Innovative therapies for neuromuscular and neurodegenerative diseases

Andera Partners, formerly known as Edmond de Rothschild Investment Partners (EdRIP) As heir to the traditions and values that have ensured the success of the Rothschild family for 250 years, the Edmond de Rothschild Group has established itself over time as a leading player in European finance. Its activities are grouped around two major areas:Private Banking and Asset Management. The Group offers wealthy families, entrepreneurs, and large institutions a full range of solutions combining a culture of tailored solutions, stability, performance, and innovation. The Edmond de Rothschild Group’s offering is characterised by strong convictions, with the desire to guarantee to each of its customers: A unique, close relationship, underpinned by the know-how and the variety of expertise of a large international group; Autonomous, experienced teams, who anticipate economic trends and innovate to establish long-term performance; The recognised stability, strength, and independence of a family-owned financial group. Founded by Baron Edmond de Rothschild in 1953, the Group has been chaired by his son, Baron Benjamin de Rothschild, since 1997.

Investment focus

Biotechnology, Health Care, Medical
Series B, Private Equity, Funding Round
France, United States, Germany

Portfolio highlights

Qualisteo — Qualisteo, a start-up company based in Nice specialised in smart grids company.
mylight150 — Mylight150 contributes to the creation of a society in which people generates own electricity to ensure self-sufficiency and long-term abundance.
Crescendo Biologics — Crescendo Biologics is a new Cambridge-based company whose vision is to deliver next-generation antibody therapeutics based on novel class-leading platforms.The focus of the company is on developing platforms that will address key issues in generating high-affinity, soluble, human VH antibody fragments. These are the smallest fragments thatretain antibody binding, and have many desirable properties as potential therapeutics. Crescendo will then utilise these platforms for product development of in-house targets or in partnership with other companies.

Sviluppo Imprese Centro Italia is an independent asset management company founded in Florence in 1998. Active in the Private Equity and Venture Capital sector, it currently manages four closed-end funds for a total value of around 140 million euro and has already carried out numerous operations. in the capital of companies operating in variousindustrial sectors, from the most traditional to high-tech. The mission of SICI is to encourage the development of unlisted SMEs in Central Italy through the contribution of financial resources intended to strengthen their capital and financial structure. SICI intends to represent a Growth Partner for the investee companies and a strategic operator in the creation of value for the territory with an impact on the economic and social fabric in terms of competitiveness of the economic system, employment, entrepreneurial and managerial culture. Business Development Central Italy is an independent Italian managing closed-end funds company. Established in Florence in 1998, SICI has 4 Private Equity and Venture funds under management with a total committed capital of 140m Euros.

Investment focus

Software, Travel, Semiconductor
Seed, Angel, Pre-Seed
Italy

Portfolio highlights

Cents — Cents is a platform that allows businesses to raise awareness in the market by supporting social and environmental causes.
Parking My Car — Parking My Car offers transportation services.
Recuperiamo srl — Recuperiamo srl is a food industry founded to prevent and reduce waste throughout the food chain. They are involved in the food industry through the Regusto brand. They can use geolocation to report on last-minute offers for their dishes.

Siamo partner di private equity con una struttura family office. Selezioniamo start-up tech-driven con idee innovative e voglia di emergere.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.
TeiaCare — TeiaCare is an Italian start-up born in 2018 with the aim of transferring technology and innovation knowledge to care homes.Our first solution, Ancelia, is an AI-powered operating system designed to increase transparency in the care and assistance processes, both inside the care home and towards residents' families.TeiaCare, based inMilan, operates in Italy and Spain, has a team of 15 people and is supported by international investors.
VoiceMed — Track respiratory health using voiceWe bring deep-tech innovation into your smartphone. With vocal biomarkers and artificial intelligence, we track the evolution of respiratory diseases.

Powering Breakthroughs in Life Sciences

Investment focus

Biotechnology, Health Care, Pharmaceutical
Series B, Series A, Series C
United States, United Kingdom, Canada

Portfolio highlights

Firefly Bio — Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.
Umoja Biopharma — Pioneering immunotherapy by reprogramming T cells in vivo to target cancer cells.
Frontier Medicines — Frontier Medicines is boldly advancing science to defeat disease by pioneering innovations in precision-based medicines to target undruggable therapies

Launch Tennessee provides startup resources to entrepreneurs, including capital sources, mentorship, accelerators, entrepreneurship training and more

Investment focus

Software, Health Care, Medical
Grant, Seed, Series A
United States, China, Italy

Portfolio highlights

DAXOR — DAXOR Corporation is an innovative medical instrumentation and biotechnology company. DAXOR designed and developed the BVA-100 Blood Volume Analyzer. It is the first instrument approved by the FDA to provide rapid direct measurement of a patient's true blood volume. We believe that the BVA-100 Blood Volume Analyzer has the potential totransform therapy in a broad range of surgical and medical conditions. It is our goal, working in conjunction with hospitals and clinics, to achieve that possibility.The BVA-100 is a semi-automated Blood Volume Analyzer. It is used in conjunction with a single use diagnostic kit. It is the first FDA-approved instrument to provide rapid direct measurement of a patient's blood volume.
Preteckt — Preteckt's AI software predicts & prevents breakdowns in buses & coaches. Reduce costs, maximize uptime, & extend vehicle life
Daily Crunch — Daily Crunch is an offline and online store that offers cherry-berry nuts, cacao sea salt, and sprouted almonds products.

Fincarl is an investment firm.

Investment focus

Medical, Health Care
Seed
Italy

Portfolio highlights

Lab Evo — Lab Evo is an Italian Digital Healthcare startup that allows customers to manage their health online with direct access to laboratory tests.

P101 is an Italian venture capital firm focused on early-stage investments in the digital sector. Agreement to handle personal data I agree I don't agree

Investment focus

Software, E-Commerce, Information Technology
Funding Round, Seed, Series A
Italy, Spain, United States

Portfolio highlights

Mundimoto — Mundimoto is a motor cycle trading platform.
Carol — Carol is a tech-enabled healthcare provider delivering membership-based primary care services, on a mission to make high-quality healthcare accessible and affordable for everyone. To achieve this goal, Carol leverages a highly scalable technology, combined with high quality clinical operations and a salaried provider model.
Cyber Guru — Cyber Guru operates as a cybersecurity awareness training platform. Cyber Guru serves to educate employees around the dangers and pitfalls of information security. The solutions use stimulating and educational learning paths to cater to those who do not hold specialist roles in the field of Cyber Security.

Alchimia is an investment company primarily operating in the Venture Capital Sector. Leveraging the expertise of our team and a wide network of international advisors, we invest and co-invest in high growth potential opportunities offering capital, as well as dedicated strategic and operational resources.

Investment focus

Health Care, Medical, Biotechnology
Series A, Seed, Funding Round
Italy, United Kingdom, Israel

Portfolio highlights

NoTraffic — NoTraffic has developed the first AI-powered traffic signal platform that connects road...
Prestatech — Prestatech is a digital credit factory that has developed an innovative underwriting platform for banks and financial institutions in Europe. Currently active with major European banks, Prestatech offers them a variety of digital credit services from data enrichment to end-to-end instant lending solutions. Thanks to technological innovation,Prestatech has gained an extensive expertise in the digital credit space and through its open-platform is currently offering API-based solutions that leverage on AI, advanced algorithms and Big Data technologies.
Chiara Ferragni — COM Chiara Ferragni

The GM&C Life Sciences Fund is a seed and early stage venture capital fund targeting life sciences businesses located in the Greater Manchester and Cheshire & Warrington region. The Fund is managed by Catapult Venture Managers ("Catapult Ventures").The Fund is based at Alderley Park, which is well recognised as a site ofnational importance, being the largest life sciences campus of its kind in the UK with more than 500,000 sq. ft. of top-end laboratory and related space and facilities. Until recently, the Park was the R&D headquarters for AstraZeneca.Since 2002, Catapult Ventures has backed a significant number of companies across a broad range of life sciences, including therapeutics (such as Abzena and Oxford BioTherapeutics), medical devices (such as Monica Healthcare and Probe Scientific), contract research organisations (such as R5 Pharmaceuticals and FDAS), diagnostics developers (such as Lumora and Biofortuna), as well as developers of technology used in healthcare applications (such as Oxford Cryosystems and Accutronics). The Fund is the result of a collaboration between Cheshire and Warrington Enterprise Partnership, Greater Manchester Combined Authority, Cheshire East Council, and Manchester Science Partnerships.

Investment focus

Health Care, Biotechnology, Medical
Seed, Funding Round, Series A
United Kingdom, Italy, Germany

Portfolio highlights

ScubaTx — ScubaTx is a breakthrough organ preservation device organ transplant. The ScubaTx device will leverage world-leading expertise in software design to commercialise a proven but unexploited organ preservation technique, Persufflation. ScubaTx will offer healthcare providers significant net savings, an
Flynotes — Flynotes is a digital software platform helping dentists deliver personalised patient care
QV Bioelectronics — Manchester-based start-up QV Bioelectronics is developing innovative electrotherapy devices for the treatment of certain types of brain tumours.

Toscana Next Fund is a co-investment fund managed by CDP Venture Capital.

Investment focus

Medical, Manufacturing, Medical Device
Pre-Seed
Italy

Portfolio highlights

Eye2Drive — EYE2DRIVE is a young company designing and building a new imaging sensor for the autonomous cars. We are based in Tuscany, Italy.
Soundsafe Care — Soundsafe care combines robotics and focused ultrasound to establish a new way to perform surgical care.

Fondazione Cottino is support young people in their educational path and support for scientific research, technology transfer.

Investment focus

Medical, mHealth, Diabetes
Seed
Italy

Portfolio highlights

D-EYE — D-EYE's technology enables healthcare professionals all over the world to quickly screen for problems, photograph them and then distribute them digitally via various secure wireless solutions. They design and manufacture diagnostic instruments.

CDP Equity is a holding company that has been set up to boost the Italian economy by investing venture capital in companies of "significant national interest" (as envisaged by the decrees of the Ministry of Economy and Finance of 3 May 2011 and 2 July 2014) or in companies with "economic, financial and capital balance, with adequateprospects of profitability and development, capable of generating value for investors"

Investment focus

SaaS, Elder Care, Small and Medium Businesses
Seed, Series A, Funding Round
Italy, United Kingdom

Portfolio highlights

Soplaya — Ordina in un click e ricevi nel tuo ristorante in 12/48h, migliaia di ingredienti direttamente dal produttore. Consegna sempre gratuita
Neuranix — Neuranix develops, manufactures, and markets innovative devices for the diagnosis of ear diseases in the medical and veterinary fields. They own several patents in the audiological field. They create products based on the analysis of the acoustic characteristics of the eardrum and middle ear measured over a broad spectrum of frequencies. Theysupport the diagnosis and monitor the therapy of middle ear pathologies.
Rubber Conversion — Rubber Conversion provides recycling, product sustainability, custom packaging, environmental impact analysis, material tracking, and online document management. Their customers contact them through phone, email, and online applications.

Fondazione Golinelli was born in Bologna in 1988 by the will of the entrepreneur and philanthropist Marino Golinelli with the aim to promote education and training, to promote the culture, to foster intellectual growth and ethics of young people, the citizens of tomorrow.

Investment focus

FinTech, Financial Services, AgTech
Seed, Pre-Seed
Italy

Portfolio highlights

Biorfarm — Adotta il tuo Albero, crea il tuo Campo Digitale e ricevi a domicilio la tua frutta biologica. Solo con Biorfarm puoi seguire la crescita dei tuoi frutti!
EvenFi — Criptalia uses blockchain technology to connect businesses that have projects to be funded with people and organizations who are looking for high-yield investments. We offer an online platform where companies publish their innovative ideas and industrial improvement projects. Investors, people, and institutions can fund these projects by lendingmoney in exchange for a higher interest rate.
Latitudo40 — Empower sustainable growth with AI-driven satellite insights from Latitudo 40. Unlock precise, real-time data for smarter urban planning, climate risk management, and industry innovation. Enhance resilience and lead with confidence.

a|impact invests in the prevailing form of equity or quasi-equity, focusing our operations mainly on companies.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.

Evotec is a global biotechnology company committed to advancing drug discovery & development together with our partners for medicines that matter.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Seed
United States, Germany, France

Portfolio highlights

Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit
Tubulis — Reimagining Antibody Drug Conjugates Tubulis generates uniquely matched protein-drug conjugates through the combination of novel proprietary technologies and disease-specific biologic insight. Our goal is to expand the therapeutic potential of antibody-drug conjugates (ADCs) by increasing design flexibility while overcoming constraints of toxicity, efficacy and indication. Tubulis will build new conjugates to fill its pipeline and
Aeovian Pharmaceuticals — Aeovian is a San Francisco based biopharmaceutical company developing novel and highly selective therapeutics modulating mTORC1 pathway.

We invest in the Metaverse

Investment focus

Gaming, Medical, PC Games
Funding Round
Italy, Brazil, United Kingdom

Portfolio highlights

4MDG — 4MDG focuses on providing various data management services such as registration portal, retail technology and customer registration.
Dubit — Choose your path in the Metaverse.
CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.

Rearden Capital is a trading and investment firm managing proprietary capital across commodity, currency, fixed income and equity asset classes and related derivative instruments in the global markets.

Investment focus

Medical, Health Care, Biotechnology
Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.

RedSeed Ventures is a Venture Capital firm investing in Early Stage Companies and Scaleups, in Europe and more particularly in Italy.

Investment focus

Retail, Crowdsourcing, Information Technology
Seed, Series A
Italy, United Kingdom

Portfolio highlights

Dianax — Milan-based Dianax was founded in 2013 starting from a group scientists led by Eugenio Iannone and Maurizio Moroni and by a few angel investors orchestrated by Gabriele Bavagnoli. Dianax mission is to develop and manufacture labs-on-chip aiming to trasform protein-based diagnostics and make it prompt, easy to use, inexpensive and reliableTheDianax novel technology is designed to make precise diagnostic results convenient, easily accessible, and affordable to patients and healthcare professionals, to empower them to effective prevention, ongoing accurate management and timely emergency treatment.The Dianax technology is the first ever application to diagnostics of a combination of microfluidic innovations and electrochemistry detection systems.Dianax was founded by Eugenio Iannone and his partners to pursue technical and market opportunities based on proprietary, independent research.
Leaf Space — Leaf Space aims to become a global leading service provider in the new, emerging microsatellite market by developing a technology platform providing all basic services required by microsatellite operators.
WIB Machines — Smart vending machines and smart lockers manufacturer pioneering smart, web-based retail automation globally. Patented solutions enabling next-gen retail.

VI Partners are Venture Capitalists successfully financing outstanding teams and innovations in the Healthcare and Technology space since 20 years.

Investment focus

Health Care, Biotechnology, Medical Device
Series A, Series B, Series C
Switzerland, Germany, United States

Portfolio highlights

Oplit — Oplit is a production planning platform that provides software and support to help industrials boost operations profitability.
XO Life — XO Life is to build the largest real-world evidence platform for patient insights for all medications and therapies. Together with one of Europe's leading research institutes for patient-centered research, the PROMIS Institute Germany of the Charité, and various pharmaceutical manufacturers, patient experiences are to be recorded in astandardized and systematic manner across a wide range of diseases. Patients are to be enabled to record their therapy course and outcome independently as well as scientifically validated so that these patient insights from real treatment practice can be used in the life science industry and by medical professions.
Somagenetix — Somagenetix is a new firm that wants to be a leader in gene therapy by developing first-in-class treatments for phagocyte-related illnesses. Somagenetix's mission is to use genetically modified phagocytes to treat patients suffering from immunodeficiency, neurodegeneration, and cancer with brain metastases.

Scientifica Venture Capital offers private equity and venture capital investment services for Italy based startups and firms.

Investment focus

Medical, Aerospace, Biotechnology
Seed, Private Equity
Italy, United Kingdom

Portfolio highlights

OhmSpace — OhmSpace provides the satellite market with reliable resistojets.
PlantBit — PlantBit is a producer of sensors and services for smart farming.
Fluid Wire Robotics — Fluid Wire Robotics sets the new standard for robots in harsh environments. We design innovative robotic arms that excel in radioactive, explosive, space, and subsea applications, avoiding the complexity and cost of traditional solutions. Our technology ensures unparalleled safety, reliability, and efficiency, redefining robot design for any challenging environment without performance loss. Discover our groundbreaking approach and robust, versatile solutions.

Seroba is a leading European life sciences venture capital firm focused on value creation through backing winning innovations in biotech and medtech.

Investment focus

Health Care, Biotechnology, Medical
Series A, Series B, Funding Round
Ireland, United States, United Kingdom

Portfolio highlights

Coave Therapeutics — Coave Therapeutics is active in the field of gene therapies in rare ocular and CNS (Central Nervous System) diseases.
ShiraTronics — ShiraTronics is in the early stages of developing new innovative therapies to combat debilitating migraine headaches. The company is focused on commercializing novel neuromodulation technologies to treat this large unmet clinical need for patients and physicians. ShiraTronics is the first spinout from NuXcel a global medical device acceleratorcompany.
Vico Therapeutics — Pioneering RNA-based science to target the root cause of rare genetic neurological diseases VO659: The first clinical candidate directly targeting the CAG repea

Exceptional Ventures is an early-stage venture capital firm that invests in entrepreneurs and businesses that improve people's lives. Founded in 2022 and is based in London, England.

Investment focus

Health Care, Food and Beverage, Biotechnology
Convertible Note, Seed, Pre-Seed
United Kingdom, Italy, France

Portfolio highlights

Circe — Circe grows their food through fermentation. Using the right fats they make food people want to eat and use CO2 as a feedstock to scale production in an economically viable and climate-friendly way.
Carol — Carol is a tech-enabled healthcare provider delivering membership-based primary care services, on a mission to make high-quality healthcare accessible and affordable for everyone. To achieve this goal, Carol leverages a highly scalable technology, combined with high quality clinical operations and a salaried provider model.
Jove Insurance — Jove provides business and protection insurance to contractors, freelancers and SMEs, powered by tech and driven by social good.

RoboIT is the National Technology Transfer Hub for Robotics and Industrial Automation.

Investment focus

Medical, Manufacturing, Medical Device
Pre-Seed
Italy

Portfolio highlights

J4Energy — Siamo la piattaforma digitale di nuova generazione per realizzare la transizione energetica industriale dalla strategia all'esecuzione.
Eye2Drive — EYE2DRIVE is a young company designing and building a new imaging sensor for the autonomous cars. We are based in Tuscany, Italy.
Fluid Wire Robotics — Fluid Wire Robotics sets the new standard for robots in harsh environments. We design innovative robotic arms that excel in radioactive, explosive, space, and subsea applications, avoiding the complexity and cost of traditional solutions. Our technology ensures unparalleled safety, reliability, and efficiency, redefining robot design for any challenging environment without performance loss. Discover our groundbreaking approach and robust, versatile solutions.

CRB Inverbio is a private venture capital management firm specialized in life sciences investing in innovative early stage start- ups in biotech, med tech, digital health and medical technologies

Investment focus

Medical, Health Care, Biotechnology
Series A, Funding Round, Seed
Spain, Mexico

Portfolio highlights

Nuubo — Nuubo is a Spanish medical device company that develops wireless, wearable technologies to monitor physiological parameters. To do so, Nuubo has a platform known as nECG DYNAMIC PLATFORM, which makes it easier to perform and read an electrocardiogram remotely. Specifically, the system patented by Nuubo is made up of three elements: a biomedicalgarment that allows the electrocardiogram signal to be captured without interfering with the patient’s daily activity; a device that continuously records the information captured by the garment and which also allows the data to be sent wirelessly and in real time for processing; and analysis and visualization software that, using artificial intelligence algorithms, can interpret all of the information transmitted by the wireless device.The devices designed by Nuubo allow patients’ hearts to be monitored for longer periods of time and without feeling uncomfortable or intrusive. The company is headquartered in Madrid, Spain.
Biocross — Biocross offers diagnostic solutions that can be used during the asymptomatic phase of the diseaseand enable early detection of individuals ..
Carol — Carol is a tech-enabled healthcare provider delivering membership-based primary care services, on a mission to make high-quality healthcare accessible and affordable for everyone. To achieve this goal, Carol leverages a highly scalable technology, combined with high quality clinical operations and a salaried provider model.

Si14 is a visionary original design and development laboratory for novel technology products that enhance the way we live, work and play. Founded in 2008 and based in Padova, Italy, Si14 turns inspiration into the realization of compelling, cutting-edge products and services that help people connect with their activities and their world, empowerenterprises in realizing greater efficiencies, improve access to vital health screening services for millions worldwide, and much more.

Investment focus

Medical, mHealth, Diabetes
Seed
Italy

Portfolio highlights

D-EYE — D-EYE's technology enables healthcare professionals all over the world to quickly screen for problems, photograph them and then distribute them digitally via various secure wireless solutions. They design and manufacture diagnostic instruments.

Finalca is an Investment Company.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.

Romed is an investment firm.

Investment focus

Medical, Wellness, Health Care
Funding Round
Italy

Portfolio highlights

BetaGlue Technologies — BetaGlue Therapeutics is a life sciences company that delivers radiotherapy from within. Introducing Yntradose, our proprietary product.

MiMiT Women's Enterprise Fund is an investment fund.

Investment focus