Top 15 Enterprise Software VC (Venture Capital) Funds in Italy in May 2025

Last updated: May 2025 A list of 15 VC (Venture Capital) funds that invest in Enterprise software startups based in Italy. We rank investors based on the number of investments they made in Enterprise software companies from Italy. We update this investor list every month.

Top 15 Enterprise Software VC (Venture Capital) Funds in Italy in May 2025

Investor	Enterprise Software Italy investments
CDP Venture Capital	3
UniCredit	3
360 Capital	2
Vento	1
The Techshop	1
Innogest Capital	1
Principia SGR	1
Invitalia Ventures	1
Angel Capital Management	1
White Bridge Investments S.p.A.	1
Friulia Finanziaria FVG	1
Aurelia Ventures	1
EuroFinLeading Private Equity	1
Terna Forward	1
AnimaTerra Investments	1

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Investor list

CDP Venture Capital Sgr - National Innovation Fund aims to make venture capital a cornerstone of the country's economic development and innovation, creating the conditions for an overall and sustainable growth of the venture capital ecosystem.

Investment focus

Software, Health Care, Information Technology
Seed, Series A, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Tundr — Tundr offers smartcard to companies for sustainable mobility.
Genius4U — Genius4U offers washing, sewing, registered mail, shipping, and parcel delivery services. They provide physiotherapist massager, osteopath, nutritionist, hairdresser, beautician, and psychologist services. They also provide professional babysitting services.
Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

UniCredit (formerly UniCredito) is an Italian global banking and financial services company. Its network spanning 50 markets in 20 countries, with more than 9,000 branches and over 148,000 employees. Its strategic position in Western and Eastern Europe gives the group one of the region's highest market shares.

Investment focus

Energy, Manufacturing, Financial Services
Debt Financing, Post-IPO Debt, Funding Round
Italy, Germany, Sweden

Portfolio highlights

La Doria — La Doria is a producer and sells tomato derivatives, ready sauces, preserved legumes, fruit juices, and beverage products. They offer products that include boiled legumes, baked beans, red kidney beans, carrots, ready-made soups and stews, and canned pasta in tomato sauce.
Unifiber — Unifiber is a broadband service company that focuses on the creation of passive access fiber optic networks.
ambrogio transporti — ambrogio transporti is a intermodal transportation company.

As an early-stage European VC, we invest from pre-seed to Series B in Deep Tech, Climate Tech, and Digital-First solutions. Embrace sustainable technological progress with us. Stay updated on the latest tech trends and portfolio news. We invest in the future now.

Investment focus

Software, E-Commerce, Information Technology
Seed, Series A, Funding Round
France, Italy, United States

Portfolio highlights

Oxyle — Permanently eliminate PFAS from your wastewater. Book a pilot and lead the way to clean, safe waters.
Resilco — Resilco develops and applies unique sustainable solutions for circular economy, carbon capture and for gas purification, both for clean production and for renewable energy applications. They offer knowledge combined with high skill in material science to solve existing and emerging problems in gas treatment.
Soource — Automate B2B sourcing with Soource AI: find and compare new suppliers, and maintain an updated database optimizing your procurement processes.

We want to empower the next generation of exceptional Italian founders by investing in and building new companies.

Investment focus

Software, Artificial Intelligence, SaaS
Pre-Seed, Seed, Angel
Italy, Germany, Switzerland

Portfolio highlights

Tundr — Tundr offers smartcard to companies for sustainable mobility.
Lexroom.ai — Lexroom.ai allows lawyers to complete hours of legal research in seconds.Legal professionals spend up to 50% of their time in repetitive, low value-adding tasks. That’s why we’re building Lexroom.ai, a product that allows lawyers to complete hours of research in seconds, so they can focus on what really matters.Lexroom.ai perfectly integrateswith lawyers' daily workflow and enables them to speed up time-consuming legal research tasks while increasing output quality, so that they can focus more on value-adding activities.Lexroom.ai is building a bridge between advanced artificial intelligence technologies and legal professionals, through a product specifically tailored to their needs.
ReportAId — ReportAId is an AI-powered software that breathes life into medical reports to make healthcare more organized, customized, and accessible.

The Techshop is a venture capital and private equity firm that invests in B2B digital startups.

Investment focus

Software, Artificial Intelligence, Financial Services
Seed, Pre-Seed, Series A
Italy, United Kingdom

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.
Shop Circle — Shop Circle is a tech-driven company that acquires and grows the best e-commerce apps. We empower thousands of brands to build experiences that customers will love.
Covision Media — Covision Media specializes in creating high-quality, relightable 3D models using their industrial 3D scanners. These scanners capture detailed surface information and PBR textures, and are designed for easy integration into virtual environments.

We are investors in companies that make the difference. We partner with hard-working entrepreneurial visionaries

Investment focus

Health Care, Medical, Medical Device
Funding Round, Series A, Series B
Italy, United States, Spain

Portfolio highlights

GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
BetaGlue Technologies — BetaGlue Therapeutics is a life sciences company that delivers radiotherapy from within. Introducing Yntradose, our proprietary product.

Principia is an Italian Venture Capital firm with over Eur 80M under management. Currently Principia has two funds investing in digital start ups and expansion capital opportunities and in particular cases, we invest also in seed opportunities.

Investment focus

Health Care, Biotechnology, Software
Funding Round, Series A, Seed
Italy, United States, United Kingdom

Portfolio highlights

KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Invitalia Ventures SGR manages the “Italia Venture Fund I”, a 87€/Ml sized co-investment fund that invests in early stage operations in Italy. They co-invest up to a maximum of 70% in round A (€ 0.5ML - € 1.5ML) in high growth sectors. Invitalia Ventures, with its network of co-investors not only provides risk capital, but also know-how and anetwork for business development. Main LPs includes the Ministery of Economic Development, the European Investment Bank, Cisco Group, the Sardinian Banking Foundation and Metec Group.They are looking for visionary entrepreneurs who share their passion for innovation. Growth is their mission!!For more information please contact us at info@invitaliaventures.it or visit our website: www.invitaliaventures.it

Investment focus

Software, Medical, Health Care
Series A, Funding Round, Seed
Italy, United States, United Kingdom

Portfolio highlights

Ecomate — The ESG Rating platform for every company
BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Founded by Angelo Moratti, Angel Capital Management (formerly Angel Lab) is a leading private investment firm providing growth equity to companies in various stages of development. The Direct Investments Practice mainly focuses on fast growing Consumer&Lifesyle companies. ACM offers its portfolio companies a comprehensive platform for growthacting as i) a partner for the international expansion of Italian companies ii) and a gateway to the Italian and South European market for foreign companies.