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Top 50 Biotechnology VC (Venture Capital) Funds in Italy in December 2024

Last updated: Dec 2024 A list of 50 VC (Venture Capital) funds that invest in Biotechnology startups based in Italy. We rank investors based on the number of investments they made in Biotechnology companies from Italy. We update this investor list every month.

Top 50 Biotechnology VC (Venture Capital) Funds in Italy in December 2024

Investor	Biotechnology Italy investments
Sofinnova Partners	11
Italian Angels for Growth	9
Indaco Venture Partners	7
Vertis	7
Principia SGR	6
LIFTT	6
Innogest Capital	6
A11 Venture	4
Green Arrow Capital	4
CDP Venture Capital	4
Invitalia Ventures	4
Atlante Ventures	4
Eureka Venture	3
Claris Ventures	3
INGENIUM Emilia Romagna	3
Club degli Investitori	3
UniCredit	2
European Investment Bank	2
Progress Tech Transfer Fund	2
Italian Angels for Biotech	2
Lazio Innova	2
StartUp Health	2
Banco BPM	2
3LB Seed Capital Srl	2
3B Future Health Fund	2
Index Ventures	1
Deep Blue Ventures	1
Atlas Venture	1
Angels4Women	1
JDRF T1D Fund	1
Scientifica Venture Capital	1
Crédit Agricole Italia	1
F3F	1
RECOMEC	1
Intesa Sanpaolo	1
Pi Campus	1
MPM Capital	1
United Ventures	1
Cube Labs	1
Padda Health	1
Istituto Nazionale Biostrutture e Biosistemi	1
Seroba Life Sciences	1
Estor	1
a\|impact	1
Evotec	1
Finalca	1
Kering Ventures	1
Sparta Capital	1
GCM Group	1
European Circular Bioeconomy Fund	1

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Investor list

Sofinnova Partners is a leading European venture capital firm in life sciences, specializing in healthcare and sustainability. Based in Paris, London and Milan, the firm brings together a team of professionals from all over the world with strong scientific, medical and business expertise.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
France, United States, United Kingdom

Portfolio highlights

deepc — The Radiology AI Platform - Your effortless access to AI
Genespire — Genespire is a biotechnology company focused on the development of transformative gene therapies for patients affected by genetic diseases, particularly primary immunodeficiencies and inherited metabolic diseases.
Micropep Technologies — Micropep Technologies developes a non-GMO new generation of bioherbicides and biostimulants. Micropep, founded in 2016 in Toulouse, focuses on bioherbicides and biostimulants. The company uses plants’ natural molecules, called “micro-peptides”, to temporarily control expression of their genes and regulate plant growth but leaving their DNA intact.The company currently works on four development programs: germination, flowering, growth, and weed control.

IAG is an angel investor network that offers access to its affiliates to early-stage venture opportunities. Its members to date have deployed over 22 million Euros to support 41 startups in the series seed/series A stage in many verticals, among which: Medtech, SAAS, e-commerce, Fintech, and high tech at large. Every investment opportunityat IAG is vetted by a professional team together with expert members of the group. Once invested, the company receives the support of up to two Investment champions, who bring their expertise to the table and help them succeed.

Investment focus

Software, E-Commerce, Health Care
Seed, Angel, Series A
Italy, United States, United Kingdom

Portfolio highlights

ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.
Rubedo Life Sciences — Rubedo Life Sciences is the Premier Longevity Company. Rubedo discovers and develops medicines to keep you biologically young.
Restorative Neurotechnologies — Siamo un'azienda di dispositivi medicali certificati per la riabilitazione cognitiva ed il trattamento di disturbi cognitivi post ictus.

VENTURE We invest across all sectors with specific focus on technology and digital The largest independent more About Us Portfolio [...]

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
Italy, Switzerland, United States

Portfolio highlights

D-Orbit — End-to-end services for the New Space industry, including platform engineering, launch and deployment, and decommissioning.
MicThera — MicThera focuses on developing microbial-derived therapeutics to provide effective treatments for prostate cancer patients, aiming to find effective solutions for medical companies.
Genespire — Genespire is a biotechnology company focused on the development of transformative gene therapies for patients affected by genetic diseases, particularly primary immunodeficiencies and inherited metabolic diseases.

Vertis is a dynamic and independent investment management company authorised by Bank of Italy. It manages five closed-end funds for qualified investors by participating in research projects, spin-offs, startups and PMI and deals with the investments of the innovative Made in Italy.

Investment focus

Software, E-Commerce, Computer
Seed, Funding Round, Series A
Italy, United States

Portfolio highlights

Aindo — Unlock the full potential of your data. The power of synthetic data integrated in a comprehensive Data Platform.
Radical Storage — Find your closest luggage storage and enjoy your journey until the very end!
Starting Finance — Starting Finance is a financial education platform intended to provide financial literacy to its users. The company's platform provides education and information about finance and publishes informative articles on important events in the fields of economics, finance, and politics, enabling users to improve their knowledge regarding finance andthe management of their capital.

Principia is an Italian Venture Capital firm with over Eur 80M under management. Currently Principia has two funds investing in digital start ups and expansion capital opportunities and in particular cases, we invest also in seed opportunities.

Investment focus

Health Care, Biotechnology, Software
Funding Round, Series A, Seed
Italy, United States, United Kingdom

Portfolio highlights

KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

A not-only-profit operating investment company, eager to create a bridge between innovative ideas, territory and capital.

Investment focus

Biotechnology, Software, Information Technology
Seed, Series A, Funding Round
Italy, United Kingdom, France

Portfolio highlights

Evoralis — Utilise Our Innovative Enzymes to Efficiently Recycle Plastics Into High-Quality Raw Materials
MicroLub — MicroLub produces a fat replacement for lower-calorie plant-based diets. It is cutting-edge innovation to the next generation of protein technology, creating exclusive ingredient solutions that significantly minimize molecular friction.
Composite Research — CoRe Research is an start-up, aimed at the study of new product and process solutions in the field of composite materials.

We are investors in companies that make the difference. We partner with hard-working entrepreneurial visionaries

Investment focus

Health Care, Medical, Medical Device
Funding Round, Series A, Series B
Italy, United States, Spain

Portfolio highlights

GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
BetaGlue Technologies — BetaGlue Therapeutics is a life sciences company that delivers radiotherapy from within. Introducing Yntradose, our proprietary product.

A11-Venture investe nel capitale di startup innovative nei settori della robotica, automazione, meccatronica, cleantech, web e IT. Facilita la nascita e lo sviluppo di business innovativi globali per il futuro dell'economia locale. Contribuisce a costruire aziende, lavoro qualificato, brevetti, innovazione capaci di rilanciare e riportareinvestimenti e risorse sul territorio. I soci di A11 Venture credono fermamente nell’innovazione grazie a ciò è possibile crescere per linee esterne diversificando i propri investimenti, grazie ad un portafoglio di imprese, con una forte risk mitigation derivante dalla gestione professionale di tutti processi: scouting, team building, investimenti, management degli investimenti, accelerazione e disinvestimento.

Investment focus

Biotechnology, Medical Device, Health Care
Seed, Pre-Seed, Series A
Italy, United States

Portfolio highlights

Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.
Neuron Guard — Neuron Guard, recognized as the best European startup in HEALTH category (Startup Europe Awards - SEUA 2017), is developing a life-saving medical device that aims to become the standard of care for Targeted Temperature Management (TTM) therapy. Every 7 seconds around the world a person suffers of Acute Brain Damage because of CardiovascularDiseases (CVD) and Traumatic Brain Injury (TBI). They are the most costly and prevalent killers in the last 15 years (15 million deaths by CVD in 2015), and the leading cause of disability (the global incidence rate of TBI is 200 per 100k people per year). WHO estimated a global expenditure of $ 330 billion in 2015, but it is going to increase sharply: $ 4 trillion in 2025 - including premature death, disability, and health care costs - just for CVD in LMICs. Temperature is a vital body parameter. It regulates all cellular functions so its management is essential for the good outcome of patients in several medical conditions such as cardiac arrest, stroke, traumatic brain injury, neuro and cardiac surgery, epilepsy, migraine and oncology. Regulating body temperature at a desired level makes all other treatments more effective. The most modern medical approach is the target temperature management, where physicians try to maintain the most favourable temperature for the patient for up to 24-36 hours, preventing excessive warming (fever) or cooling.Our device is a targeted temperature management system composed by a THERAPEUTIC COLLAR POWERED BY A SMART CONTROL UNIT (the size of a small briefcase). The collar transforms the neck into a natural heat exchanger exploiting several physiological and anatomical characteristics of the human body. It is quicker to act on brain tissue but can also function as total body temperature adjusting device if required. A disposable protective shield makes cleaning the collar after each use simple while featuring an optimal safety profile both in term of pathogens and allergens. The control unit collects all the data of the treatment and transmits them to the Emergency Response System. Our mission is to improve the safety of patients on the roadside, at home or in the workplace, and to reduce the costs of chronic care. In fact, Neuron Guard aims to be the only device that can be used in every circumstance, inside and outside the hospital, and allow the user to fully manage the temperature of the patient warming and cooling as necessary. Our vision is to have a Neuron Guard kit in every public place just like the Automatic External Defibrillator (AED) to empower bystanders to immediately react in case of emergency. Under this perspective our device becomes a connected-intelligent platform that takes care of the patient, connects the scene with the Emergency Response System transmitting vital data to improve the readiness and effectiveness of professional intervention.The device is patented in Italy, USA and China. We have made several prototypes in collaboration with Italian and English companies, such as Tecno Elettra Impianti and TWI, tested it in laboratory and published the experimental results on the NeuroCritical Care Journal. We have also conducted a GAP Analysis with another English consulting firm (CDP) and we are testing the human prototype internally. We are seeking to raise 2.5M€ to complete the pre-industrialization, with design and construction of the human device for the pilot trial, finalized the regulatory clearance and launch it into the market in 2019.

Green Arrow Capital is an independent financial group specializing in alternative investments across Europe. They represent a one-of-a-kind platform, capable of connecting the financial system with the real economy through the management of private equity, private debt, infrastructure, and special credit situation funds as well as thematic fundssuch as microfinance and funds of funds that are currently under management. Their team has a successful track record in asset management, investment banking, industry sectors, technology startups, management consulting, renewable energy, and has government and regulatory experience. Their group is mainly composed of investment, asset management, and financial advisory companies. Their aim is to create a solid financial platform to launch and manage investment funds dedicated to alternatives and to the real economy.

Investment focus

Health Care, Biotechnology, Manufacturing
Funding Round, Seed, Series A
Italy, United Kingdom

Portfolio highlights

Cogisen — Cogisen develops artificial intelligence solutions. It offers SENCOGI, an eye-tracking software for smartphones/mobile phones. Chiara Passacantilli and Christiaan Erik Rijnders founded Cogisen in 2009. Its headquarters is in Naples in Italy.
Directa Plus — Directa Plus is a nanotechnology company, manufactures nanoparticles.
Glomeria Therapeutics — Glomeria Therapeutics researches, develops, and markets new medical devices for the treatment of serious diseases in the nephrological area. It offers DesmoPD, peritoneal dialysis connection system; SmartPD, an automated management device for peritoneal dialysis solutions to be instilled in peritoneum; and solutions for peritoneal dialysis.Andrea Zanella founded Glomeria Therapeutics in 2010. Its headquarters is in Chieti in Italy.

CDP Venture Capital Sgr - National Innovation Fund aims to make venture capital a cornerstone of the country's economic development and innovation, creating the conditions for an overall and sustainable growth of the venture capital ecosystem.

Investment focus

Software, Information Technology, Health Care
Seed, Series A, Funding Round
Italy, United States, Germany

Portfolio highlights

Waxy — Waxy is an innovative startup that operates in the domain of designing, building, and distributing technologies for the sanitization of liquids and food products.
Tau Group — E-mobility is powered by its core - the electric motor. We at Tau are at the very core of the core: the copper winding wire, the magnetic core, the electrical steel.We just make it bet.
Restorative Neurotechnologies — Siamo un'azienda di dispositivi medicali certificati per la riabilitazione cognitiva ed il trattamento di disturbi cognitivi post ictus.

Invitalia Ventures SGR manages the “Italia Venture Fund I”, a 87€/Ml sized co-investment fund that invests in early stage operations in Italy. They co-invest up to a maximum of 70% in round A (€ 0.5ML - € 1.5ML) in high growth sectors. Invitalia Ventures, with its network of co-investors not only provides risk capital, but also know-how and anetwork for business development. Main LPs includes the Ministery of Economic Development, the European Investment Bank, Cisco Group, the Sardinian Banking Foundation and Metec Group.They are looking for visionary entrepreneurs who share their passion for innovation. Growth is their mission!!For more information please contact us at info@invitaliaventures.it or visit our website: www.invitaliaventures.it

Investment focus

Software, Medical, Health Care
Series A, Funding Round, Seed
Italy, United States, United Kingdom

Portfolio highlights

Ecomate — The ESG Rating platform for every company
BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Atlante Ventures is a leading Italian VC fund, operated by IMI Fondi Chiusi SGR, part of Intesa Sanpaolo Group.

Investment focus

Software, Biotechnology, Hardware
Funding Round, Seed, Series A
Italy, United States, Israel

Portfolio highlights

treet — Treet helps brands launch fully-branded recommerce sites where customers can buy & sell items from each other.
Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Eureka! is the first independent Italian venture capital Asset Management company exclusively focused on deep tech investments

Investment focus

Nanotechnology, Renewable Energy, Medical Device
Funding Round, Seed, Pre-Seed
Italy

Portfolio highlights

Planckian — Charging the future by powering energy with science We explore frontiers of energy science by developing quantum...
INTA Systems — Nanotech and artificial intelligence for biomolecular analysis
BeDimensional — We produce graphene and others two-dimensional materials (2D) with few atomic layers. Find out more.

Claris Ventures is a venture capital firm supporting the best scientists in building successful life sciences companies that will impact people's lives

Investment focus

Biotechnology, Health Care, Therapeutics
Seed, Series A, Series B
Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.
Repron Therapeutics — Repron Therapeutics provides treatments for solid tumor cases where radical excision is not possible and metastasis or recurrence is extremely likely.

INGENIUM Emilia Romagna was started with EUR 5.30 million by the Emilia Romagna region and EUR 1.7 million from fund managers. Managed by META Investment, the nine-year fund operated through the temporary acquisition of minority stakes in high-opportunity technological companies. It is now fully invested.

Investment focus

Medical, Health Care, Privacy
Seed, Angel, Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.
GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Angiodroid — Angiodroid srl, a medical technology company, focuses on hemodynamics, vascular surgery, and interventional radiology. It offers an automatic injection system for carbon dioxide angiography. Its products include carbon dioxide injector that is used as a contrast medium for pheriperal interventional angiography; and a single use kit, which iscomposed of French catheters and a custom connection line. The company is based in San Lazzaro di Savena, Italy.

Club degli Investitori (Investors Club) is a network of investors and business angels that invest on early-stage SMEs and startups. The community of 300+ Members (entrepreneurs, CEOs, executive managers) actively scouts for investing opportunities on SMEs & startups and invests with a minimum ticket of €200k. The Club supports business byinvesting capital and by leveraging the Members' network and experience.Club degli Investitori is supported by Unicredit and KPMG Italy.

Investment focus

Health Care, E-Commerce, Information Technology
Seed, Series A, Series B
Italy, Switzerland, United Kingdom

Portfolio highlights

Ephos — Designing and manufacturing glass-based integrated photonic circuits that power the most advanced classical and quantum devices
Stema — It serves as a platform for hiring engineers
Lymphatica Medtech — Lymphatica Medtech is a medical device development company developing a minimally invasive solution for chronic lymphedema.Lymphedema is the chronic swelling that generally occurs in the arms or the legs.Lymphedema is most commonly caused by the removal of or the damage to the lymph nodes as a part of cancer treatment. It results from ablockage in the lymphatic system, which is part of the immune system. The blockage prevents the lymphatic system from draining excess fluids, and the fluid buildup leads to swelling, infections, and pain.Unfortunately, there is no cure for lymphedema. It can be managed with early diagnosis and diligent care of the affected limb, through daily compression, bandages, and manual drainage sessions. From the moment of the diagnosis, the life of lymphedema patients changes forever.Cancer and cancer-related interventions (i.e. surgery, radiotherapy) are frequent causes of lymphedema occurring both in the upper and lower limbs. Breast cancer survivors are at high risk for developing lymphedema, as well as patients treated for melanoma, pelvic and head and neck cancer or other cancer treatments that require lymph node dissection. Physical trauma can also result in lymphedema, a major cause of lymphatic disease among wounded veterans.Lymphedema is associated with significantly impaired quality of life, skin changes, increased risk of infection and in rare cases lymphedema itself may undergo malignant transformation.Lymphatica offers a permanent solution that will allow patients to regain their normal lifestyle.

UniCredit (formerly UniCredito) is an Italian global banking and financial services company. Its network spanning 50 markets in 20 countries, with more than 9,000 branches and over 148,000 employees. Its strategic position in Western and Eastern Europe gives the group one of the region's highest market shares.

Investment focus

Energy, Manufacturing, Financial Services
Debt Financing, Post-IPO Debt, Funding Round
Italy, Germany, Sweden

Portfolio highlights

La Doria — La Doria is a producer and sells tomato derivatives, ready sauces, preserved legumes, fruit juices, and beverage products. They offer products that include boiled legumes, baked beans, red kidney beans, carrots, ready-made soups and stews, and canned pasta in tomato sauce.
Unifiber — Unifiber is a broadband service company that focuses on the creation of passive access fiber optic networks.
ambrogio transporti — ambrogio transporti is a intermodal transportation company.

European Investment Bank (EIB) provides lending, borrowing, and treasury services primarily in the European Union.The company offers project loans for the public and private sectors; loans to banks and other intermediaries; structured finance products; guarantees and securitization instruments for senior and subordinated debts; project bonds;equity and fund investment products such as infrastructure equity and debt funds, and environmental funds; and venture capital funds and security packages for funds.The company also offers microfinance; risk sharing finance for research, development, and innovation projects; finance and technical expertise for sustainable energy projects; infrastructure project advisory services; support for urban development projects; guarantees for transport infrastructure; and funding for public-private partnerships and small- and medium-sized enterprises.EIB serves the transportation, global loans, energy, industry, health, education, water, sewerage, infrastructure, services, telecommunications, agriculture, and fisheries sectors.European Investment Bank was founded in 1958 and is based in Luxembourg.

Investment focus

Biotechnology, Health Care, Energy
Debt Financing, Post-IPO Debt, Funding Round
France, Germany, The Netherlands

Portfolio highlights

BURN — The future of clean cooking
GEWOBA — GEWOBA is a real estate company that manages and provides a diverse portfolio of rental real estate apartments and properties.
Acea — Acea operates in six business segments. The water segment collects, purchases, transports and distributes drinking water, and manages the sewerage system and the purification of wastewaters. The company serves 9 million residents served in Lazio, Tuscany, Umbria, Molise and Campania; The energy segment manages the transmission and distributesroughly 9 TWh of electricity, public lighting; commercial and trading segment activities include energy management, sale of electricity and gas, energy efficiency for domestic customers. The company is targeting growth in electricity generation from renewable (photovoltaic) sources and in electric mobility, with a view to effectively contributing more and more to the energy transition and decarbonisation. The environment segment provides laboratory, research and related consultancy services on the environment and control functions within the water cycle; engineering services and overseas operations providing water services in Latin America.

Investment fund specialized in sustainable technologies from universities and public research organizations, start-ups, spin-offs, and entrepreneurs.

Investment focus

Water, Eyewear, Farming
Seed, Series A, Pre-Seed
Italy, Ireland

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
WembraneX — WembraneX's goal is to make wastewater treatment facilities more cost-effective by introducing a new class of anti-fouling and anti-biofouling membranes.
Valuematic — Valuematic realizza soluzioni per il trattamento e gestione dei dati favorendo il miglioramento nei processi organizzativi e informativi di aziende ed enti.

Angel group focuses on biotech

Investment focus

Health Care, Biotechnology, Pharmaceutical
Seed
Italy

Portfolio highlights

MgShell — MgShell offers intraocular devices for the treatment of age-related macular degeneration and other ocular diseases. Their technology is the only technical solution capable of replicating current clinical practice with a single injection and releasing the same therapeutic drug doses at predetermined periods, autonomously and without surgicalprocedures.
CaSRevolution — A novel disease-modifying approach against neurodegeneration
Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

Lazio Innova is a venture capital firm with its headquarters in Rome in Italy. The firm provides services in areas such as credit support and guarantees, interventions in risk capital, internationalization services, promotion of business networks and services for the creation and enterprise development.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Pre-Seed, Grant
Italy, United Kingdom

Portfolio highlights

Joinrs — We developed an artificial intelligence model able to read job offers for you and show you the ones that best match your profile.
Medicud — Medicud develops a device for treating wounds with negative pressure dressing.
Ticketoo — Ticketoo: compra e vendi biglietti fan-to-fan in modo sicuro

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
Pear Suite — Pear Suite empowers community health workers with technology, education, and community, helping them do their best work and serve their communities.
Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs

Scopri i servizi bancari e finanziari di Banco BPM: conti, mutui, carte, prestiti, assicurazioni, trading e tanto altro. Per privati e imprese.

Investment focus

Manufacturing, Product Design, Energy
Debt Financing, Post-IPO Debt, Pre-Seed
Italy, United States, Spain

Portfolio highlights

Maire Tecnimont — We are enablers of innovation, working alongside businesses to develop sustainable technologies and design integrated solutions that inspire energy transition.
Enel Green Power — Enel Green Power is the company that deals with renewable energy from every perspective: from direct sales through PPA, to commitment at the forefront with its plants worldwide.
Garofalo Health Care — Garofalo Health Care SpA is a major group in Italy in the authorized private healthcare sector and the only Italian firm listed on the Star division of the Italian Stock Exchange in the healthcare industry.

3LB Seed Capital is not an alternative to start-ups incubators and accelerators, rather acts as a complementary reality that helps to enhance your project in terms of attractiveness for the investor and venture capital market.As investors they are the first willing to know if your project has what it takes to grow successfully. If they areconvinced of your potential, they are ready to bet on you, by joining you and helping you to develop your project.3LB Seed Capital does not provide a percentage of equity in exchange for accompanying activities, but relies exclusively on a premium at the time of its first direct investment in your company.

Investment focus

E-Commerce, Software, Information Technology
Seed, Pre-Seed, Series A
Italy, United States, United Kingdom

Portfolio highlights

YoAgents — Yo Agents nasce dalla unione delle competenze di ogni singolo founder messe a fattor comune per creare un sales hub innovativo.
Botsociety — Your conversational design suite. Design and prototype your next chatbot or voice assistant. Create a mockup of your project on Messenger, Slack, Google Assistant, Alexa and more. The next generation design solution for chatbots and voice.
Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

Helsinn Investment Fund S.A. is a Luxembourg fund focused on early-stage investments in areas of high unmet patient need.

Investment focus

Biotechnology, Therapeutics, Medical
Series B, Series A, Funding Round
United States, Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
Fore Biotherapeutics — We are a precision oncology company pioneering the development of cancer therapies guided by our proprietary functional genomics.
On Target Laboratories — ON TARGET LABORATORIES discovers and develops fluorescent markers to target and illuminate cancer during surgery so it can be removed more completely.

Index Ventures is an international venture capital firm with dual headquarters in San Francisco and London, investing in technology-enabled companies with a focus on e-commerce, fintech, mobility, gaming, infrastructure/AI, and security.

Investment focus

Software, E-Commerce, Internet
Series A, Series B, Seed
United States, United Kingdom, France

Portfolio highlights

Tessl — Tessl transforms software development for the AI era with its innovative AI-native development approach. Its AI-powered development platform provides secure, high-quality, and self-maintaining code tailored to the user's requirements.
Vooma — Vooma is a back-office automation platform that enables automated order entry for brokers and carriers.
Workflow — A minimalist collaboration platform for creative teams. Manage tasks, get AI reviews, and share work, all in one place.

DEEP BLUE VENTURES Venture Capital Fund DEEP BLUE VENTURES DBV Deep Blue Ventures is our first Venture Capital fund DBV is an early stage deep tech fund, investing in outstanding deep technologies, and people able to harnessing them to great global success. Deep Blue Ventures

Investment focus

Biotechnology, Medical Device, Artificial Intelligence
Seed
Italy

Portfolio highlights

INTA Systems — Nanotech and artificial intelligence for biomolecular analysis

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, United Kingdom, Canada

Portfolio highlights

Judo Bio — Judo Bio is pioneering oligonucleotide medicines delivered to the kidney, opening the way for new treatments for systemic and renal diseases.
Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
Trace Neuroscience — Trace Neuroscience is a biopharmaceutical company that aims to extend the promise of genetic medicine to patients with neurodegenerative illnesses.

Angels4Women is a company that invests in business startups lead by females.

Investment focus

Retail, Fashion, Lingerie
Seed, Angel, Funding Round
Italy, United States

Portfolio highlights

Diamante — Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.
FUTURELY — FUTURELY is a platform which will help to choose university.
Chite Milano — Lingerie the Italian way. Discover 100% Made in Italy lingerie. Make your own: customise your lingerie and nightwear.

The JDRF T1D Fund (www.t1dfund.org) is a venture philanthropy fund exclusively devoted to finding and funding the best early-stage T1D commercial opportunities to accelerate the delivery of treatments, preventions, and cures to patients. It was created to solve a critical funding gap in the T1D drug and device development pipeline. Throughpartnerships with private capital, including venture capital, pharma and foundations, the T1D Fund anticipates that it will be able to attract substantially more private investment to the T1D field than occurs today. The T1D Fund will initially focus on artificial pancreas systems, metabolic control, beta cell replacement, prevention, and beta cell restoration therapies, with an exclusive priority on the best commercial opportunities. The T1D Fund will reinvest any realized gains into new investments to further its mission.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Funding Round
United States, Italy, Canada

Portfolio highlights

DiogenX — We incorporated DiogenX with the objective to provide new therapeutic solutions for diabetic patients. With Patrick Collombat and the team, we are focused on developing a first-in-class regenerative treatment for type 1 diabetes. Benjamin Charles CEO See the team News See more Our Work OUR APPROACH ABOUT DIABETES
Inversago Pharma — Inversago Pharma is a preclinical-stage, biotech company specialized in the development of new therapies focusing on CB1 blockade, based on first-in-class, peripherally-acting, CB1 inverse agonists.
Code Biotherapeutics — Code Biotherapeutics is an emerging next-generation gene therapy company pioneering the development of targeted non-viral gene therapies to treat serious and life-threatening genetic diseases not well served by other gene therapy technologies.

Scientifica Venture Capital offers private equity and venture capital investment services for Italy based startups and firms.

Investment focus

Medical, Aerospace, Biotechnology
Seed, Private Equity
Italy, United Kingdom

Portfolio highlights

OhmSpace — OhmSpace provides the satellite market with reliable resistojets.
QuantaBrain — QuantaBrain purpose is to accelerate the diagnosis of psychiatric and neurodevelopmental diseases by applying artificial intelligence.
Fluid Wire Robotics — Fluid Wire Robotics sets the new standard for robots in harsh environments. We design innovative robotic arms that excel in radioactive, explosive, space, and subsea applications, avoiding the complexity and cost of traditional solutions. Our technology ensures unparalleled safety, reliability, and efficiency, redefining robot design for any challenging environment without performance loss. Discover our groundbreaking approach and robust, versatile solutions.

Crédit Agricole Italia is a bank that offers loans and financial services.

Investment focus

Financial Services, Finance, Water
Debt Financing, Seed
Italy

Portfolio highlights

Italcer Group — Italcer Group is a manufacturer of indoor and outdoor ceramic products.
Clessidra — Clessidra Private Equity is an investment firm that invests in the Italian upper-middle markets. Clessidra Private Equity was founded in 2003 and was headquartered in Milan, Italy.
Generalfinance — Generalfinance is a financial management agency that provides flexible services designed to address the company's debt issues.

F3F

Investment focus

Hardware, Hospital, Software
Series A, Series C
Italy

Portfolio highlights

Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

RECOMEC operates as a venture capital firm that primarily invests in the healthcare sector.

Investment focus

Medical, Health Care, Biotechnology
Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.

Intesa Sanpaolo is a banking group that specializes in wealth management, protection, advisory, and digital orientation. Their products and services include accounts, cards, loans, mortgages, insurance, digital payments, retirement planning, investments, and consulting.

Investment focus

Financial Services, FinTech, Renewable Energy
Debt Financing, Post-IPO Debt, Series A
Italy, United Kingdom, United States

Portfolio highlights

La Doria — La Doria is a producer and sells tomato derivatives, ready sauces, preserved legumes, fruit juices, and beverage products. They offer products that include boiled legumes, baked beans, red kidney beans, carrots, ready-made soups and stews, and canned pasta in tomato sauce.
MODIFI — Explore digital trade finance and B2B payment solutions that empower your business to grow globally.
Maire Tecnimont — We are enablers of innovation, working alongside businesses to develop sustainable technologies and design integrated solutions that inspire energy transition.

Pi Campus is a startup district and a venture fund that invests in talent. We provide startups with money, mentorship and the best work environment for growth.

Investment focus

Software, Mobile, Biotechnology
Seed, Pre-Seed, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Loquis — La prima piattaforma per ascoltare e raccontare il mondo tramite podcast geolocalizzati
Fondo — Fondo is an all-in-one accounting platform for startups. We'll handle your bookkeeping, tax, and tax credits so you can focus on building your startup.
Intron Health — Intron is the future of clinical documentation with real-time clinical speech-to-text for 200+ African accents, easing the transition to digitized care.

Powering Breakthroughs in Life Sciences

Investment focus

Biotechnology, Health Care, Pharmaceutical
Series B, Series A, Series C
United States, United Kingdom, Canada

Portfolio highlights

AstronauTx — AstronauTx is a UCL spin-off, will develop medicines designed to reset the behaviour of astrocytes.
Firefly Bio — Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.
Frontier Medicines — Frontier Medicines is boldly advancing science to defeat disease by pioneering innovations in precision-based medicines to target undruggable therapies

We are an independent Venture Capitalfirm supporting visionary entrepreneurs toreinvent industries through technology.

Investment focus

Software, FinTech, Information Technology
Series A, Seed, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Exein — Exein provides the most advanced IoT security solution to protect your devices and containers. Protect your IoT devices in real time and at scale.
Avaneidi — Discover Avaneidi's enterprise storage solutions. Designed in Italy with a 'security by design' approach for unparalleled security and reliability.
IdentifAI — IdentifAI pioneers discerning human-AI creations, bolstering authenticity with advanced models. Determine if an image come from AI or from human!

We enable innovation

Investment focus

Wellness, Health Care, Biotechnology
Corporate Round
Italy

Portfolio highlights

Adamas Biotech — More than a decade of basic research in the field of botanical function-specific antioxidants. The nutraceutical solutions proposed to stem from a patented protected technology.

Siamo partner di private equity con una struttura family office. Selezioniamo start-up tech-driven con idee innovative e voglia di emergere.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.
TeiaCare — TeiaCare is an Italian start-up born in 2018 with the aim of transferring technology and innovation knowledge to care homes.Our first solution, Ancelia, is an AI-powered operating system designed to increase transparency in the care and assistance processes, both inside the care home and towards residents' families.TeiaCare, based inMilan, operates in Italy and Spain, has a team of 15 people and is supported by international investors.
VoiceMed — Track respiratory health using voiceWe bring deep-tech innovation into your smartphone. With vocal biomarkers and artificial intelligence, we track the evolution of respiratory diseases.

Istituto Nazionale Biostrutture e Biosistemi is a platform for biostructures and biosystems that represent the intersection and the synthesis between the life sciences and physical sciences.

Investment focus

Wellness, Health Care, Biotechnology
Corporate Round
Italy

Portfolio highlights

Adamas Biotech — More than a decade of basic research in the field of botanical function-specific antioxidants. The nutraceutical solutions proposed to stem from a patented protected technology.

Seroba is a leading European life sciences venture capital firm focused on value creation through backing winning innovations in biotech and medtech.

Investment focus

Health Care, Biotechnology, Medical
Series A, Series B, Funding Round
Ireland, United States, United Kingdom

Portfolio highlights

Shorla Pharma — Shorla Pharma is an Irish specialty pharmaceutical company. It is growing portfolio brings accessible, affordable and life-saving treatments to patients, delivering a major contribution to patient care and providing a significant clinical impact.
Vico Therapeutics — Vico Therapeutics is a developer of ribonucleic acid (RNA) modulating therapies for rare neurological disorders. The company discovers, develops, and delivers therapies for CNS disorders. Its initial focus is on SCA which is a subgroup of hereditary ataxia, HD which is a neurodegenerative disorder, and RTT-a neurodevelopmental disorder primarilyaffecting girls that enable clients with providing therapy for it.Vico Therapeutics was founded in 2019 by Luc Dochez, Josh Mandel-Brehm, Judith van Deutekom, and Gail Mandel and it is headquartered in Leiden, The Netherlands.
Artica Therapeutics — Artica Therapeutics specializes in biotechnological research and development for medical devices, pharmaceutical processes, and food.

Estor is a Investment Firm.

Investment focus

Health Care, Biotechnology, Medical Device
Seed
Italy

Portfolio highlights

Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.

a|impact invests in the prevailing form of equity or quasi-equity, focusing our operations mainly on companies.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.

Evotec is a global biotechnology company committed to advancing drug discovery & development together with our partners for medicines that matter.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Seed
United States, Germany, France

Portfolio highlights

Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit
Tubulis — Reimagining Antibody Drug Conjugates Tubulis generates uniquely matched protein-drug conjugates through the combination of novel proprietary technologies and disease-specific biologic insight. Our goal is to expand the therapeutic potential of antibody-drug conjugates (ADCs) by increasing design flexibility while overcoming constraints of toxicity, efficacy and indication. Tubulis will build new conjugates to fill its pipeline and
Aeovian Pharmaceuticals — Aeovian is a San Francisco based biopharmaceutical company developing novel and highly selective therapeutics modulating mTORC1 pathway.

Finalca is an Investment Company.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.

Kering Ventures is the venture investment arm of the Kering Group, acquiring minority holdings in startups.

Investment focus

Biotechnology, Interior Design
Series A
Italy

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.

Sparta Capital Ltd. focuses on product development, manufacturing, distribution, sales and service across a range of technologies. The Company's offering includes four different market verticals: transportation, mining, construction and energy (through biomass conversion). These offerings include optimization of energy consumption in thecommercial and manufacturing sectors, construction and energy through biomass conversion, energy conservation in mining, and energy savings in transportation. It is focused on the expansion of a range of divisions, including photoluminescent safety products division, energy audit (EMD) division, biomass division and mining division.

Investment focus

Solar, Life Science, Biotechnology
Series A, Series B
Italy, Germany

Portfolio highlights

Sunvigo — Sunvigo provides you with cheap solar power from your roof and real green power from the grid.
GFBiochemicals — GFBiochemicals is the only company to produce levulinic acid derivatives at commercial scale directly from biomass.

GCM Group is an investment firm.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.

European Circular Bioeconomy Fund invest and partner with entrepreneurs to accelerate late-stage circular bioeconomy companies.

Investment focus

Biotechnology, AgTech, Agriculture
Series B, Series A, Series C
The Netherlands, France, Italy

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
OroraTech — OroraTech provides global real-time information services. The first target market is early detection and monitoring of wildfires, extended by a proprietary constellation of thermal imaging nanosatellites equipped with in-space AI image processing. At the beginning of 2020, OroraTech launched an MVP called Wildfire Service (WFS) that enables quickdetection and monitoring of wildfires on a global scale. The combination of existing thermal-infrared satellite data with external data layers, such as fuel, wind, and risk maps results in an automatic generation of fire alerts and the display of current fire perimeters for users. The MVP was launched in early 2020 and has gained increasing traction with governmental and large corporate customers all over the world.
watttron — Watttron invents a revolutionary heating system that can heat up surfaces heterogeneously.Watttron develops an innovative heating technology that can be used in various industrial processes. It is superior to current heating systems in many ways and offers a number of advantages. On the following pages, you will find information about possibleapplications and opportunities.The company is located in the Technologie- und Gründerzentrum Freital – a technology and start-up center on the outskirts of Dresden, the state capital of Saxony.

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