Top 50 Biotechnology VC Funds & Investors in Italy (October 2026)

Portfolio highlights

• Evja — Evja supports growers in optimizing the management and monitoring of irrigation, nutrition and protection of their crops through the use of OPI, the most advanced system for precision agriculture .
• TrueLayer — We power faster and safer online payments with our open banking payments network. Onboard users, accept payments & make payouts in seconds. Learn more today.
• Tretau — E-mobility is powered by its core - the electric motor. We at Tau are at the very core of the core: the copper winding wire, the magnetic core, the electrical steel.We just make it bet.

Portfolio highlights

• Odoo — From ERP to CRM, eCommerce and CMS. Download Odoo or use it in the cloud. Grow Your Business.
• HighLife — HighLife is driven by a mission to deliver innovative treatment options to patients suffering from heart valve diseases.
• EnginZyme — Enzymatic chemistry for cleaner ingredients in personal care, food and pharma. Enginzyme's patented EziG platform makes enzymes work at industrial scale.

Portfolio highlights

• Newcleo — newcleo is the clean and safe nuclear technology company. Privately funded and headquartered in London, UK, newcleo was launched in 2021 to be a disruptor in the field of nuclear energy. Its mission is to generate safe, clean and inexhaustible energy for the world, through a radically innovative combination of existing, accessible technologies.newcleo is building the next generation system with the goals to: (1) eliminate the need for geological repositories by using a fast neutron flux avoiding production of long life radioactive elements; (2) develop an Accelerator Driven System (ADS), based on the intrinsically safe coupling of a particle accelerator and a sub-critical reactor; (3) accelerate the development of new fuel cycles, including thorium, that provide economic, clean, safe and inexhaustible energy from nuclei and the opportunity to burn the long-lived nuclear waste produced by the old generation of nuclear reactors.With visionary co-founders, newcleo brings together a team of engineers with deep knowledge of nuclear energy with younger recruits with a fresh mindset, working to design an innovative micro Lead Fast Reactor with significant commercial applications, for example in shipping. newcleo wants to be the first step toward the evolution of its industry to become fully respectful of people and the environment. To develop a new, sustainable, and completely safe way of generating nuclear energy that will lead humanity to zero emissions, and to the mitigation of global warming.
• Easy Rain — Leading a new automotive era: our modular ecosystem of virtual sensors and active hardware makes cars and autonomous platforms truly safe in every condition.
• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit

Portfolio highlights

• Cato AI — Search, analyze and bid on Italian public tenders with AI, automating the manual work for bid offices and sales teams.
• AUDIOGEN — Generate your sounds with AI. Create an infinite world of sounds - sound effects, samples, and music, instantly. Get Started Free.
• Alomana — Alomana is an organization that focuses on harnessing the power of artificial intelligence and data analytics to drive insights and innovation across various industries. They offer a range of services, including data analysis, machine learning model development, and AI-driven solutions tailored to meet the specific needs of their clients. Datasparkemphasizes the importance of data-driven decision-making and works closely with businesses to implement strategies that enhance operational efficiency and improve outcomes. With a commitment to advancing the use of AI and data analytics, Dataspark aims to empower organizations to unlock the full potential of their data and stay competitive in a rapidly changing market.

Portfolio highlights

• Clastix — Clastix is an enterprise Kubernetes infrastructure company, purpose-built to solve the operational challenges that emerge when Kubernetes runs at scale: cluster sprawl, fragile multi-tenancy, and the mounting cost of over-provisioned hardware and memory. The company's breakthrough is architectural. By combining hosted control planes with hard multi-tenancy, Clastix enables telcos, cloud providers, MSPs, and platform teams to run many isolated Kubernetes environments more efficiently, securely, and cost-effectively than traditional approaches allow. Clastix was founded by engineers who understood these pain points from direct experience running Kubernetes in production. That same commitment to quality engineering runs through everything the company builds – an approach shaped as much by Italian engineering tradition as by technical rigour. The result is infrastructure software that is functional, elegant, and highly scalable. The company's open source credentials are equally strong. Clastix donated Capsule to the Cloud Native Computing Foundation, co-founded Cloud Native Days Italy, and continues to evolve Kamaji – contributing not just code, but community and standards to the broader Kubernetes ecosystem. Clastix's platform is trusted by customers including NVIDIA and Mistral AI – organisations that operate some of the most demanding and innovation-intensive infrastructure environments in the world. Their confidence is a direct measure of what the platform can handle. Headquartered in Naples, Italy, with customers and partners across cloud, data centre, edge, and AI infrastructure globally, Clastix is where world-class engineering meets the real operational complexity of modern Kubernetes at scale.
• Tiledesk — Boost customer engagement with Tiledesk. Discover our conversational automation ready to use. Personalized experiences, improved conversion and retention.
• Comestai — Comestai focuses on digital and in-person treatment pathways for people with eating disorders. The company operates a hybrid care model that combines online consultations with psychologists, psychotherapists, psychiatrists, and clinical dietitians and access to physical clinical spaces. It offers virtual multidisciplinary therapy programs tailoredto individuals and families, with structured assessments and follow-up sessions. Comestai also develops corporate welfare programs that provide counseling groups, psychoeducational tools, and consultation modules for employees in partner organizations. Through its La Palestra di Animenta branch, it delivers structured professional training, including multi-module courses and continuing medical education pathways for clinicians treating eating disorders. Comestai additionally produces digital educational content such as the Hilde newsletter to support families and caregivers with practical information and clinical guidance about eating disorders.

Portfolio highlights

• Lever Bio — Lever Bio aims to translate groundbreaking discoveries in immuno-oncology into next-generation cancer immunotherapies.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.
• Haptena Therapeutics — Haptena Therapeutics develops next-generation immunotherapies for oncogene-driven cancers, integrating precision oncology and immune engineering. Our research focuses on KRAS-mutant tumors to deliver more effective and durable treatment options.

Portfolio highlights

• CareGlance — CareGlance is the provider of real-time monitoring systems based on SS-OCT technology. Fast, precise and developed for the industry!
• Rainbow Crops — Rainbow Crops is a next-generation Agtech company developing climate-resilient, high-performing crop varieties.
• Wearable Robotics — Wearable Robotics produces and develops wearable robotic systems and exoskeletons for rehabilitation, assistance and human-power augmentation.

Portfolio highlights

• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
• Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
• BetaGlue Technologies — BetaGlue Technologies engage in the research and offers anticancer products.

Portfolio highlights

• KLISBio — KLISBio is a clinical-stage regenerative medicine company focused on developing innovative technology platforms based entirely on natural silk fibroin. The company, headquartered in Milan, Italy, currently has several assets under development, such as vascular graft, bone graft substitutes, rotator cuff repair, drug release, and a first-in-humanstudy on nerve repair that is ongoing at the University of Zurich, Switzerland
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• CareGlance — CareGlance is the provider of real-time monitoring systems based on SS-OCT technology. Fast, precise and developed for the industry!
• ACTIVE LABEL — ACTIVE LABEL is a label on which a film containing one milligram of silicate or fluorohalide powder is applied. With this label, it enables checking whether the optimal storage temperature range has been respected during transport/storage, and thus certifies the quality and safety of the packaged product, also allowing to recalculate theexpiry date of the asset.
• BeDimensional — New Material Solution

Portfolio highlights

• Banxware — Banxware provides the technology and the funds for business financing of any kind: fully embedded in your platform or as an affiliate solution - all managed by Banxware
• DevTwo S.p.A. — DevTwo S.p.A. is a special purpose vehicle belonging to Gruppo Barletta,
• Telebit — Telebit Group is a system integrator and solution provider operating in the telecommunications, ICT, technological plant engineering, and energy sectors.

Portfolio highlights

• Soource — Soource is a B2B Saas product that uses AI applications to help purchasing managers to discover the best market solutions through extensive global research and automated email negotiations with thousands of suppliers worldwide.
• Comestai — Comestai focuses on digital and in-person treatment pathways for people with eating disorders. The company operates a hybrid care model that combines online consultations with psychologists, psychotherapists, psychiatrists, and clinical dietitians and access to physical clinical spaces. It offers virtual multidisciplinary therapy programs tailoredto individuals and families, with structured assessments and follow-up sessions. Comestai also develops corporate welfare programs that provide counseling groups, psychoeducational tools, and consultation modules for employees in partner organizations. Through its La Palestra di Animenta branch, it delivers structured professional training, including multi-module courses and continuing medical education pathways for clinicians treating eating disorders. Comestai additionally produces digital educational content such as the Hilde newsletter to support families and caregivers with practical information and clinical guidance about eating disorders.
• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit

Portfolio highlights

• Dialybrid — Dialybrid provide product that include silkothane arteriovenous graft, SAG biomimetic nanostructure, and situ tissue engineering products. Their proprietary innovative technology, silkothane, is a hybrid material combining silk fibroin and polyurethane. Their aim is to develop a novel semi-degradable vascular access for hemodialysis.
• EpilepsyGTx — EpilepsyGTx is a late-stage biotech company exploring cutting-edge gene therapies to improve the management of focal refractory epilepsy (FRE).
• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit

Portfolio highlights

• CaSRevolution — A novel disease-modifying approach against neurodegeneration
• Lighthouse Biotech — Lighthouse Biotech offers a liquid biopsy tool that helps to extract live and intact circulating tumor cells from a simple blood sample, to avoid repetition with altered metabolism, helping medical staff and doctors to trace and treat tumor cells in the very early stages of the disease.

Portfolio highlights

• Relicta — Relicta solution is a water-soluble bioplastic material obtained from fish processing waste and suitable for packaging solutions.
• OhmSpace — OhmSpace provides the satellite market with reliable resistojets.
• LOTO Biotech — LOTO Biotech is a biotechnology platform focused on supporting the development of treatments for rare diseases, particularly those caused by dominant negative genetic mutations.

Portfolio highlights

• Pieralisi — Pieralisi is provides revolutionized traditional olive oil extraction systems, conquering domestic and international markets with the first decanter for olive-oil continuous processing.
• Maticmind S.p.A — Maticmind S.p.A is a company that provides ICT and system integration solutions to telecommunications operators.
• Green Future Project — Software e consulenza ESG per misurare, ridurre e rendicontare l'impatto secondo CSRD e VSME, con progetti climatici certificati. Scopri Green Future Project.

Portfolio highlights

• Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
• AdapTronics — AdapTronics is a deep-tech startup that produces adaptive mechatronic devices to make logistics sustainable on Earth and in space. Its adaptive mechatronics technology offers an alternative based on a multifunctional electrostatic membrane that allows the gripping and manipulation of objects of any shape. In addition, it offers a thin-filmtechnology with sensor capabilities that becomes adhesive when electrically activated.
• Neuron Guard — Neuron Guard, recognized as the best European startup in HEALTH category (Startup Europe Awards - SEUA 2017), is developing a life-saving medical device that aims to become the standard of care for Targeted Temperature Management (TTM) therapy. Every 7 seconds around the world a person suffers of Acute Brain Damage because of CardiovascularDiseases (CVD) and Traumatic Brain Injury (TBI). They are the most costly and prevalent killers in the last 15 years (15 million deaths by CVD in 2015), and the leading cause of disability (the global incidence rate of TBI is 200 per 100k people per year). WHO estimated a global expenditure of $ 330 billion in 2015, but it is going to increase sharply: $ 4 trillion in 2025 - including premature death, disability, and health care costs - just for CVD in LMICs. Temperature is a vital body parameter. It regulates all cellular functions so its management is essential for the good outcome of patients in several medical conditions such as cardiac arrest, stroke, traumatic brain injury, neuro and cardiac surgery, epilepsy, migraine and oncology. Regulating body temperature at a desired level makes all other treatments more effective. The most modern medical approach is the target temperature management, where physicians try to maintain the most favourable temperature for the patient for up to 24-36 hours, preventing excessive warming (fever) or cooling.Our device is a targeted temperature management system composed by a THERAPEUTIC COLLAR POWERED BY A SMART CONTROL UNIT (the size of a small briefcase). The collar transforms the neck into a natural heat exchanger exploiting several physiological and anatomical characteristics of the human body. It is quicker to act on brain tissue but can also function as total body temperature adjusting device if required. A disposable protective shield makes cleaning the collar after each use simple while featuring an optimal safety profile both in term of pathogens and allergens. The control unit collects all the data of the treatment and transmits them to the Emergency Response System. Our mission is to improve the safety of patients on the roadside, at home or in the workplace, and to reduce the costs of chronic care. In fact, Neuron Guard aims to be the only device that can be used in every circumstance, inside and outside the hospital, and allow the user to fully manage the temperature of the patient warming and cooling as necessary. Our vision is to have a Neuron Guard kit in every public place just like the Automatic External Defibrillator (AED) to empower bystanders to immediately react in case of emergency. Under this perspective our device becomes a connected-intelligent platform that takes care of the patient, connects the scene with the Emergency Response System transmitting vital data to improve the readiness and effectiveness of professional intervention.The device is patented in Italy, USA and China. We have made several prototypes in collaboration with Italian and English companies, such as Tecno Elettra Impianti and TWI, tested it in laboratory and published the experimental results on the NeuroCritical Care Journal. We have also conducted a GAP Analysis with another English consulting firm (CDP) and we are testing the human prototype internally. We are seeking to raise 2.5M€ to complete the pre-industrialization, with design and construction of the human device for the pilot trial, finalized the regulatory clearance and launch it into the market in 2019.

Portfolio highlights

• Gility — Gility is a digital learning platform that collaborates with business schools and training institutions for an effective training offer. Established in 2022, it was supported by CDP Venture Capital and BPER Banca.
• Soplaya — Soplaya is a B2B food company connecting chefs and farmers to build a diverse, sustainable, and efficient food system.By providing data and transparency to an opaque supply chain, we help chefs to simplify purchases, get a wider selection of products and save money and farmers to increase their margins and get easy access to the market.We lovequality food as much as technology and automation. We are rebels: we love transparency and how the internet is capable of bringing the long tail to the market. We're excited about the fact that the restaurant supply chain hasn't basically changed since 40 years, and was technology reluctant for a long time, but restaurants necessities changed dramatically in the last 3 years.We’re becoming the standard layer for restaurant purchasing across Europe, by bringing transparency and simplicity in the procurement phase, increasing order frequency, promoting lean inventory and food waste reduction.
• Valvitalia SpA. — VALVITALIA is a leading group in the field of design, production, and overall supply of equipment and components intended for the petroleum, water, natural gas industries, and petrochemical industry as well as electrical power stations. The group works mainly with valves (core product), actuators, pipe fittings, flanges and systems for measuring,filtering, and regulating fluids and gases and with FireFighting systems. VALVITALIA was set up with the precise objective of becoming the leading Italian group able to offer such a wide range of products and to compete with the large American multinationals that have always dominated this field. This young company has extensive experience in the sector, thanks to its professional management and historical brands in the valve world that have been taken on by the Group, including: ROTOR, DELTA V.E., THEVIGNOT, VANADOUR, VITAS, TORMENE T.G.T. and TECNOFORGE. VALVITALIA has always included safety and respect for the environment and its employees among its priorities.

Portfolio highlights

• HEU — Draft, sign and store contracts in one place. AI extracts deadlines and clauses, signatures valid in 180+ countries.
• Tech4All — We support the study by using AI.
• GeneSys Bio — Antimicrobial Resistance (AMR) is a global health emergency projected to cause 10 million deaths annually by 2050. The crisis is fueled by slow, conventional diagnostics that take 3-5 days, forcing the empirical use of broad-spectrum antibiotics and accelerating the spread of superbugs.GeneSys Bio is commercialising a breakthrough solution: afully automated, sample-to-result molecular diagnostic platform that identifies infectious pathogens and their critical antibiotic resistance genes in under 30 minutes with >99% sensitivity and specificity. Our portable, laptop-sized device combines proprietary nucleic acid amplification with an AI-driven engine to deliver clear, actionable results directly to clinicians, veterinarians, and public health officials.Our platform is a modular "One Health" solution, adaptable via disease-specific kits for human, veterinary, and environmental applications. We are entering the market with a diagnostic for Urinary Tract Infections (UTIs), a condition affecting over 500 million people annually and a primary driver of antibiotic misuse. By enabling targeted therapy at the first patient encounter, our platform is set to reduce treatment costs by up to 13%, cut follow-up visits, and decrease mortality from complicated infections by 50%.GeneSys Bio is positioned to capture a significant share of this market by bridging the critical gap between speed, laboratory-grade accuracy, and accessibility. We are not just creating a device; we are building the future of decentralized infectious disease diagnostics to safeguard global health for generations to come

Portfolio highlights

• treet — Treet helps brands launch fully-branded recommerce sites where customers can buy & sell items from each other.
• ADmantX — A NEW ERA OF AUDIENCE TARGETINGADmantX is a contextual analysis and data provider that brings audience targeting to a new level. Awarded patent for semantic advertising technology, the company offers a cookie-less solution that allows publishers, ad networks and exchanges, brand managers and agencies to develop more effective online adcampaigns leveraging semantic understanding, natural language processing and sentiment analysis. Founded in Italy as a spin-off of the leading semantic company Expert System, ADmantX is active in Europe and US. Worldwide customers include NBCUniversal, Integral Ad Science, Networked Insights, Banzai, Cadreon, Amnet, Sojern, Media IQ and ADmantX solutions are integrated in key DSP players such as Turn, Adform and AppNexus.
• YOGITECH — Notizie e approfondimenti di Tecnologia

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — BigProfiles is an Artificial Intelligence Platform designed for Utilities, Telcos, Banks, Insurance companies and Retails.Large companies such as Teleperformance, Eni, Unicef already have already successfully subscribed to our services.BigProfiles is the No-Code Artificial Intelligence Platform for sales and antichurn that predicts thelikelihood to purchase and churn of each customer in a CRM, before proceeding to contact him in a sales or retention campaign.
• Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Portfolio highlights

• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.
• BrainDTech — Early detection and monitoring of neurological and neurodegenerative diseases through miRNA profiles from microglial microvesicles.

Portfolio highlights

• MgShell — MgShell offers intraocular devices for the treatment of age-related macular degeneration and other ocular diseases. Their technology is the only technical solution capable of replicating current clinical practice with a single injection and releasing the same therapeutic drug doses at predetermined periods, autonomously and without surgicalprocedures.
• CaSRevolution — A novel disease-modifying approach against neurodegeneration
• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit

Portfolio highlights

• RougeTx — RougeTx is a Netherlands-based biotech developing first-in-class small-molecule therapies for vascular diseases caused by pericyte dysfunction. Its lead candidate, RTX-001, targets hereditary haemorrhagic telangiectasia (HHT), an inherited disorder involving fragile blood vessels and recurrent bleeding.
• MedinCell — Join Medincell on a journey to transform global health with innovative therapies.
• Santander Brasil — Banco Santander in Brazil, its largest division in Latin America and one of the world's most important, accounting for 50%.

Portfolio highlights

• Neuromod Devices — Neuromod is the global medical device company that developed Lenire, the FDA Approved tinnitus treatment device.
• DISCO Pharmaceuticals — DISCO Pharmaceuticals is a firm that specializes in large-scale surfaceome unlocking of cancer cells.
• Endovascular Engineering — Endovascular Engineering is a medical technology company focused on developing and deploying advanced clot removal solutions for the treatment of venous thromboembolism. It specializes in thrombectomy technologies designed to improve clinical outcomes and procedural efficiency in minimally invasive vascular interventions. The company’s flagshipinnovation is the Hēlo™ Thrombectomy System, a catheter-based device that uses a combination of mechanical agitation and physician-controlled aspiration to remove blood clots. Its technology emphasizes features such as a self-expanding funnel design and dual-action functionality to enhance clot engagement and navigation through complex anatomies. Endovascular Engineering primarily serves healthcare providers, including interventional cardiologists and radiologists, supporting the treatment of conditions such as pulmonary embolism and deep vein thrombosis.

Portfolio highlights

• Wakuli — It's called specialty coffee. Roasted lighter to enhance all the exciting flavours. To really taste them it's important to drink fresh. That's why we send our mailbox-friendly coffee within one week after roasting. And always with a better price for the farmers - thanks to you.
• Reduced — Reduced develops natural flavor enhancers from upcycled produce.
• foodforecast — AI supported solution to reduce food waste.

Portfolio highlights

• Kymia — Natural extracts from pistachio hulls for cosmetics, nutraceuticals, and food & beverages. Effective and sustainable ingredients to enhance your products.
• Noiet — Noiet is a biotechnology firm whose mission is to develop clean, natural, and fermented proteins that serve as multifunctional alternatives.
• Alma Serum — Alma Serum is a cosmetic and biotech company that turns dairy industry into advanced cosmetic and biomedical materials.

Portfolio highlights

• Fazland — Fazland is an innovative web and mobile platform developed by the Italian startup Midnight Call Srl. The platform enables private clients to compare offers for home services and it helps efficient tradesmen to get in touch with potential customers in an easy and smart way. Midnight Call Srl was founded in October 2011 in Reggio Emilia (Italy).Following an initial phase of R&D, the product has become commercially available in March 2013.Following a very encouraging first year of operations, the company recieved a seed investment from the Italian venture capital fund RedSeed Ventures and some Angel Investors in July 2014. Through continuous product improvements and a solid commercial approach, the company has managed to build a solid position in the Italian market and launch pilot tests in few European cities.
• Passpack — Users can make and store passwords in a single, organized list, then access them from anywhere leaving no traces behind on the computer. Secure collaboration features allow users to make, send, share or provision passwords to colleagues, clients and partners -- a secure alternative to spreadsheets in the workplace. Managed via a central onlinerepository.Passpack is a free, professional tool. Optional premium upgrades are available for the micro-small business sector.
• GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.

Portfolio highlights

• AGADE — Esoscheletri Agade | Il primo esoscheletro intelligente per lavoratori progettato per ridurre il rischio di disturbi muscolari delle spalle nella movimentazione manuale dei carichi.
• BroadBit Batteries — BroadBit is a technology company developing revolutionary new batteries using novel sodium-based chemistries to power the future green economy.
• Aenitis Technologies — We develop innovative devices for cells therapy processing using Acoustic Radiation Forces.

Portfolio highlights

• MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
• SQIM — SQIM is a biotechnological based agency.
• Superplastic — Superplastic is a character-based product and entertainment company. It creates limited edition art toys, apparel, games, and animation based on characters created in collaboration with some of the greatest artists in the world. Superplastic is founded on the principle that effort and scarcity are intrinsic components of value. The companyappropriates the tools of mass media and mass production to create limited edition works of art for a limited audience. It was established in 2017 and is based in Burlington, Vermont.

Portfolio highlights

• WembraneX — WembraneX's goal is to make wastewater treatment facilities more cost-effective by introducing a new class of anti-fouling and anti-biofouling membranes.
• Naturbeads — Naturbeads creates biodegradable, sustainable and cost competitive cellulose microbeads to replace currently used microplastics.
• Valuematic — Valuematic realizza soluzioni per il trattamento e gestione dei dati favorendo il miglioramento nei processi organizzativi e informativi di aziende ed enti.

Portfolio highlights

• K3RX — K3RX products for thermal protection systems of the next generation of hypersonic vehicles and rocket motor inserts of satellite launchers demonstrate their performance. K3RX manufactures tiles in uhtcmc material, rocket nozzles, screws, nuts, and support mechanical connectors.
• Eye2Drive — Eye2Drive designs bio-inspired, AI-ready CMOS image sensors for autonomous navigation, eliminating flickering and ghosting while significantly enhancing safety.
• Fluid Wire Robotics — A fully electric robotic platform for extreme environments: nuclear, space, cryogenic, ATEX and subsea. Manipulation where conventional robots cannot go.

Portfolio highlights

• GenEp — GenEp, Inc. is a pre-clinical stage biotechnology company based on intellectual property assets. GenEp creates therapies targeting mutations of sodium and other ion channels that cause rare genetic epilepsies and other treatment-resistant epilepsies.
• Kainova Therapeutics — Domain Therapeutics is a biopharmaceutical company focused on GPCR in immuno-oncology. Discover more than you think on our innovative cancer treatments tackling GPCR mediated-immunosuppression
• Navion Neurosciences — Navion Neurosciences is a preclinical-stage biotechnology company developing next-generation, precision sodium channel therapies for neurological diseases.

Portfolio highlights

• Biorsaf — Biorsaf is an IT company that develops mobile apps and web control panels to assist companies to bring efficiency to their operations.
• Rainbow Crops — Rainbow Crops is a next-generation Agtech company developing climate-resilient, high-performing crop varieties.
• Metabolize — Metabolize provdies wellness and fitness services that helps with global metabolic health and obesity epidemic

Portfolio highlights

• MMI — The future of Microsurgery: microinstruments that expand the possibilities of surgical interventions. Wristed robotic microinstruments for unprecedented results in microsurgery.
• RougeTx — RougeTx is a Netherlands-based biotech developing first-in-class small-molecule therapies for vascular diseases caused by pericyte dysfunction. Its lead candidate, RTX-001, targets hereditary haemorrhagic telangiectasia (HHT), an inherited disorder involving fragile blood vessels and recurrent bleeding.
• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit

Portfolio highlights

• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...
• Recornea — Recornea is a developer of a corneal medical device to restore the physiological curvature of the cornea with clear and predictable clinical outcomes.
• Health Triage — Health Triage, crea nuove tecnologie per offrire modelli innovativi di diagnosi clinica, identificazione e cura delle malattie oncologiche.

Portfolio highlights

• SimpL — SimpL is an Italy-based AI sales-intelligence and prospecting platform for B2B sales teams. It researches target companies, identifies relevant buying signals, drafts personalised LinkedIn outreach, manages follow-ups, and helps generate qualified sales meetings.
• Computis — Computis is an AI company offering software solutions for electronic invoicing, bank reconciliation, tax estimation, and billing services.
• Helix Robotics — We are building the first commercial soft manipulator

Portfolio highlights

• AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
• Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs
• NEXT Life Sciences — NEXT Life Sciences is developing the revolutionary Plan A™ procedure to bring the only scientifically proven technology in the category - Vasalgel® - to market.

Portfolio highlights

• Windrose Holding — Windrose Holding S.r.l. operates as a dedicated special-purpose sub-holding company that indirectly manages a clean energy asset portfolio with a combined capacity of approximately 157 MW. The entity focuses on the financial optimization, operation, and strategic refinancing of established onshore wind farms and solar photovoltaic plants. It functions as the direct borrowing vehicle for institutional utility-scale grid financing, utilizing structured corporate credit lines like green loans. The company is structured to absorb and manage wholesale merchant risk on its mixed asset portfolio once state-backed tariff incentives expire.
• M-Cube Digital Engagement — M-Cube Digital Engagement engages in the creation of audio-visual solutions for in-store marketing. M-Cube in-store digital engagement helps businesses around the world deploying innovative digital technology and multi-media content to provide a seamless online to offline customer experience.
• Polo Strategico Nazionale — Scopri Polo Strategico Nazionale: il cloud sovrano per la gestione dei dati e servizi della Pubblica Amministrazione italiana.

Portfolio highlights

• P2 Science — Using green chemistry to create high performance, clean ingredient solutions, P2 Science is delivering sustainability to the world of beauty.
• NOUS Energy — Empowering your business in Nutraceutical and F&B sector with functional solutions designed around your need
• Cosaic — Cultivated - Creamy, dairy-free indulgence

Portfolio highlights

• Iusful — Iusful is a legal services company that provides legal solutions for contracts, intellectual property, and compliance.
• Cato AI — Search, analyze and bid on Italian public tenders with AI, automating the manual work for bid offices and sales teams.
• Computis — Computis is an AI company offering software solutions for electronic invoicing, bank reconciliation, tax estimation, and billing services.

Portfolio highlights

• Pack — Pack is the people development platform that empowers HR with data-driven insights, digital assessments, and world-class mentoring & coaching. Unlock employee growth with tailored development plans, AI-driven tracking, and an international network of experts.
• Roboze — Roboze is able to engineer high performance thermoplastic polymers resistant to the most extreme operating conditions for various sectors.
• Keyless — Reverify and authenticate your users in a glance, without storing biometric data. PingOne Recognize delivers private, fraud-resistant biometric authentication.

Portfolio highlights

• Fluencify — Fluencify is an innovative creator marketing platform that runs end to end user generated content programs for global brands. The software powered solution enforces brand quality guidelines, handles global creator payments, and provides contracted view guarantees to turn influencer marketing into a scalable utility framework.
• Verda — Verda provides a full-stack AI cloud platform for the development, training, and deployment of AI models. Its services include GPU instances, instant clusters, serverless containers, managed storage, and other cloud infrastructure powered by NVIDIA hardware. Verda also operates an AI Lab focused on large-scale training, inference optimization, reinforcement learning, and AI systems engineering. Its platform serves AI developers and organizations across the full AI lifecycle, from prototyping to scalable inference.
• Cota Robotics — Cota Robotics deploys general-purpose robots in retail stores through a Robot-as-a-Service model, integrating with existing environments without requiring changes to store layouts or infrastructure. The company automates shelf replenishment, inbound handling, and order picking using human-in-the-loop teleoperation, with autonomy increasing asdeployment data trains its models.

Portfolio highlights

• YoAgents — Yo Agents nasce dalla unione delle competenze di ogni singolo founder messe a fattor comune per creare un sales hub innovativo.
• Botsociety — Your conversational design suite. Design and prototype your next chatbot or voice assistant. Create a mockup of your project on Messenger, Slack, Google Assistant, Alexa and more. The next generation design solution for chatbots and voice.
• Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

Portfolio highlights

• Aptadir Therapeutics — Reprogramming DNA methylation in disease conditions by RNA therapeutics APTADIR Contact us NEWS Press Release Reprogramming DNA methylation by RNA therapeutics A novel therapeutic approach for untreatable cancers and rare diseases Aberrant methylation by DNA methyltransferase 1 (DNMT1) of certain genes may cause abnormal cell development and lead to disease. Current therapies targeted to inhibit
• Tubulis — Reimagining Antibody Drug Conjugates Tubulis generates uniquely matched protein-drug conjugates through the combination of novel proprietary technologies and disease-specific biologic insight. Our goal is to expand the therapeutic potential of antibody-drug conjugates (ADCs) by increasing design flexibility while overcoming constraints of toxicity, efficacy and indication. Tubulis will build new conjugates to fill its pipeline and
• Aeovian Pharmaceuticals — Aeovian is a San Francisco based biopharmaceutical company developing novel and highly selective therapeutics modulating mTORC1 pathway.

Portfolio highlights

• Tracelight — Tracelight is the leading AI assistant for financial modelling in Excel. Build models, automate workflows, format at scale, and check for errors - we are the AI for analysts.
• Hyperdrives — Discover Hyperdrives, a deep-tech engineering company providing electric drive systems designed to set a new benchmark for performance-to-cost.
• Windup Minds — Stay: Forever Home is a heartwarming virtual pet game where you meet Ember, a magical companion bringing joy, adventure, and connection. Discover her emerging world, uncover hidden treats, and build your forever home together!

Portfolio highlights

• ScubaTx — ScubaTx is a breakthrough organ preservation device organ transplant. The ScubaTx device will leverage world-leading expertise in software design to commercialise a proven but unexploited organ preservation technique, Persufflation. ScubaTx will offer healthcare providers significant net savings, an
• Infex Therapeutics — Infex Therapeutics acquires, develops and licenses innovative drugs to treat pandemic infections
• Monument Therapeutics — Monument Therapeutics is a biotechnology company intended to develop drugs to treat serious diseases of the central nervous system.

Portfolio highlights

• TeiaCare — TeiaCare is an Italian start-up born in 2018 with the aim of transferring technology and innovation knowledge to care homes.Our first solution, Ancelia, is an AI-powered operating system designed to increase transparency in the care and assistance processes, both inside the care home and towards residents' families.TeiaCare, based inMilan, operates in Italy and Spain, has a team of 15 people and is supported by international investors.
• VoiceMed — We bring deep-tech innovation into your smartphone. With vocal biomarkers and artificial intelligence, we measure respiratory diseases.
• Hale — Hale is the digital solution supporting people with genito-pelvic pain, helping them live better with their condition. Download our app now!

Portfolio highlights

• Diamante — Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.
• Envirly — Envirly is a Polish technology company that offers an innovative platform for managing sustainable development, and the carbon footprint of organizations and products.
• Vado — Vado is a technology startup that connects third-party delivery platforms and vending machines making order reception, management and delivery to the riders completely automatic.We are neither a delivery provider nor a vending machine manufacturer - we bridge the gap between them.In order to help companies manage the delivery and take-awayoperations of any product (Alcohol, Sushi, Drugs, Ready Foods) more efficiently, we integrate their delivery apps (Glovo, Deliveroo, JustEat, UberEats) with distributors automatic that allow you to sell automatically 24/7.Automating the online ordering process helps our customers save time and money, so they can focus more on their core business and continue doing what they love most: making their customers happy.

Portfolio highlights

• Allara — Allara is your all-in-one virtual care team for hormonal, metabolic & gynecological conditions such as PCOS and Endometriosis.
• nexos.ai — Introducing nexos.ai — a powerful model gateway that delivers game-changing AI solutions. With advanced automation and intelligent decision making, nexos.ai helps simplify operations, boost productivity, and accelerate business growth.
• Instabase — Instabase combines the latest AI breakthroughs with industry expertise to create real business value for your business.