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Top 50 Biotechnology VC Funds in Italy

Last updated: Apr 2024 A list of 50 VC funds that invest in Biotechnology startups based in Italy. We rank investors based on the number of investments they made in Biotechnology companies from Italy. We update this investor list every month.

Top 50 Biotechnology VC Funds in Italy

Investor	Biotechnology Italy investments
Sofinnova Partners	11
Italian Angels for Growth	9
Indaco Venture Partners	7
Vertis SGR S.p.A.	7
Principia SGR	6
Innogest Capital	6
LIFTT	5
Invitalia Ventures	4
Atlante Ventures	4
A11 Venture	4
Green Arrow Capital	4
Club degli Investitori	3
Eureka Venture	3
CDP Venture Capital	3
Claris Ventures	3
Italian Angels for Biotech	2
StartUp Health	2
3B Future Health Fund	2
European Investment Bank	2
Progress Tech Transfer Fund	2
Lazio Innova	2
INGENIUM Emilia Romagna	2
Crédit Agricole Italia	1
Banco BPM	1
Angels 4 Impact	1
Oskare Capital	1
3LB Seed Capital Srl	1
Sparta Capital	1
Utopia	1
AbbVie Biotech Ventures	1
United Ventures	1
Panakes Partners	1
Intesa Sanpaolo	1
Schia Ventures	1
a\|impact	1
Atlas Venture	1
MPM Capital	1
Estor	1
Seroba Life Sciences	1
Padda Health	1
Riso Gallo	1
European Commission	1
Lombardstreet Ventures	1
Angels4Women	1
F3F	1
FoolFarm	1
Scientifica Venture Capital	1
Launch Tennessee	1
Finalca	1
JDRF T1D Fund	1

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Investor list

Sofinnova Partners is a leading European venture capital firm in life sciences, specializing in healthcare and sustainability. Based in Paris, London and Milan, the firm brings together a team of professionals from all over the world with strong scientific, medical and business expertise.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
France, United States, United Kingdom

Portfolio highlights

Cure51 — Cure51 mission is to create a database of cancer survivors to leverage their exceptional biological features and find new drugs to cure Cancer.
Bioptimus — Our mission is to build the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovations in biomedicine and beyond.
MISSION Therapeutics — Deubiquitylating enzymes: multiple drug opportunities across therapeutic areas

IAG is an angel investor network that offers access to its affiliates to early-stage venture opportunities. Its members to date have deployed over 22 million Euros to support 41 startups in the series seed/series A stage in many verticals, among which: Medtech, SAAS, e-commerce, Fintech, and high tech at large. Every investment opportunityat IAG is vetted by a professional team together with expert members of the group. Once invested, the company receives the support of up to two Investment champions, who bring their expertise to the table and help them succeed.

Investment focus

Software, E-Commerce, Health Care
Seed, Angel, Series A
Italy, United States, United Kingdom

Portfolio highlights

ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.
Viceversa — Viceversa provides capital to European digital businesses to support companies in sustainable and ethical growth. The company was founded in 2021 and has locations in Milan and Dublin.
Clearbox AI — Benefit from Synthetic Data to unlock your AI projects, overcome privacy issues and improve the utility of your data.

VENTURE We invest across all sectors with specific focus on technology and digital The largest independent more About Us Portfolio [...]

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
Easy Rain — We are Easyrain. Continuous innovation runs in our blood.With our expertise, we develop, simulate, and test solutions, launching our ideas into production. We exploit the basic laws of physics to engineer a tangible solution!
Alia Therapeutics — Alia Therapeutics is developing next-generation gene-editing medicines to cure rare genetic diseases.

Vertis is a dynamic and independent investment management company authorised by Bank of Italy. It manages five closed-end funds for qualified investors by participating in research projects, spin-offs, startups and PMI and deals with the investments of the innovative Made in Italy.

Investment focus

Software, E-Commerce, Computer
Seed, Funding Round, Series A
Italy, United States

Portfolio highlights

NEWTWEN — We develop software that generates real-time embedded digital twin solutions for model predictive control and diagnostics of electromechanical systems, enhancing performance, longevity, and reliability. In essence, our toolchain creates a precise digital replica of a physical device, such as an electric motor or generator, in order to accuratelymodel the electrodynamic and thermodynamic behavior of the system across a wide range of operating conditions. We then apply our proprietary mathematical approach to exponentially reduce the computational complexity of this model—so much so, in fact, that our digital twin can be integrated into the device itself to compute in real-time, “on-chip,” as part of an amazingly fast and accurate firmware solution. By accurately predicting temperatures and other critical system parameters thousands of times per second, our Digital Twin On-Chip solutions not only provide unprecedented insight for real-time control techniques to enhance system performance, but also pave the way for data-as-a-service capabilities such as predictive maintenance, monitoring of component aging, and anomaly detection.
Coverzen — The digital office of insurers
Sibylla Biotech — Sibylla Biotech developed small molecule folding interfering degraders (FIDs) that can address a range of therapeutic areas.

Principia is an Italian Venture Capital firm with over Eur 80M under management. Currently Principia has two funds investing in digital start ups and expansion capital opportunities and in particular cases, we invest also in seed opportunities.

Investment focus

Health Care, Biotechnology, Software
Funding Round, Series A, Seed
Italy, United States, United Kingdom

Portfolio highlights

KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

We are investors in companies that make the difference. We partner with hard-working entrepreneurial visionaries

Investment focus

Health Care, Medical, Medical Device
Funding Round, Series A, Series B
Italy, United States, Spain

Portfolio highlights

GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Renovacor — Renovacor is a preclinical‑stage biopharmaceutical company focused on developing transformative gene therapy‑based treatments for cardiovascular disease.Renovacor’s lead program is a recombinant adeno-associated virus (AAV)‑based gene therapy for patients suffering from dilated cardiomyopathy (DCM) due to mutations in the Bcl2‑associatedathanogene 3 (BAG3) gene.Dilated cardiomyopathy is a condition affecting over 3 million patients in the US and growing steadily. Many patients develop DCM due to ischemic heart disease. Recently subpopulations have been identified that develop DCM due to mutations in specific genes that have been shown to result in the development of DCM. One of these specific genes is the BAG3 gene. The prevalence of disease‑causing BAG3 haploinsufficiency is estimated at approximately 35,000 individuals in the United States, representing an orphan disease by FDA guidelines. It is estimated a similar number of DCM patients with BAG3 mutations exist in Europe. These patients are typically younger and progress to end-stage heart failure sooner than patients with ischemic heart disease. Currently, DCM patients with a BAG3 mutation are treated with standard of care for heart failure. Despite improvements in pharmacotherapy and care, the five‑year survival of a patient with DCM is only 50%. The development of a BAG3 gene replacement therapy for patients with DCM that carry BAG3 mutations could potentially prevent the progression of disease in this otherwise healthy population of young adults.
BetaGlue Technologies — BetaGlue Technologies engage in the research and offers anticancer products.

A not-only-profit operating investment company, eager to create a bridge between innovative ideas, territory and capital.

Investment focus

Software, Biotechnology, Health Care
Seed, Series A, Funding Round
Italy, United Kingdom, Switzerland

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
SteerLight — SteerLight is a startup that develops LiDAR-based optical sensors, also known as laser-based optical systems, to aid with mobility.
ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.

Invitalia Ventures SGR manages the “Italia Venture Fund I”, a 87€/Ml sized co-investment fund that invests in early stage operations in Italy. They co-invest up to a maximum of 70% in round A (€ 0.5ML - € 1.5ML) in high growth sectors. Invitalia Ventures, with its network of co-investors not only provides risk capital, but also know-how and anetwork for business development. Main LPs includes the Ministery of Economic Development, the European Investment Bank, Cisco Group, the Sardinian Banking Foundation and Metec Group.They are looking for visionary entrepreneurs who share their passion for innovation. Growth is their mission!!For more information please contact us at info@invitaliaventures.it or visit our website: www.invitaliaventures.it

Investment focus

Software, Medical, Health Care
Series A, Funding Round, Seed
Italy, United States, United Kingdom

Portfolio highlights

Ecomate — The ESG Rating platform for every company
BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Atlante Ventures is a leading Italian VC fund, operated by IMI Fondi Chiusi SGR, part of Intesa Sanpaolo Group.

Investment focus

Software, Biotechnology, Hardware
Funding Round, Seed, Series A
Italy, United States, Israel

Portfolio highlights

treet — Treet helps brands launch fully-branded recommerce sites where customers can buy & sell items from each other.
Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

A11-Venture investe nel capitale di startup innovative nei settori della robotica, automazione, meccatronica, cleantech, web e IT. Facilita la nascita e lo sviluppo di business innovativi globali per il futuro dell'economia locale. Contribuisce a costruire aziende, lavoro qualificato, brevetti, innovazione capaci di rilanciare e riportareinvestimenti e risorse sul territorio. I soci di A11 Venture credono fermamente nell’innovazione grazie a ciò è possibile crescere per linee esterne diversificando i propri investimenti, grazie ad un portafoglio di imprese, con una forte risk mitigation derivante dalla gestione professionale di tutti processi: scouting, team building, investimenti, management degli investimenti, accelerazione e disinvestimento.

Investment focus

Biotechnology, Medical Device, Health Care
Seed, Pre-Seed, Series A
Italy, United States

Portfolio highlights

Reefilla — Reefilla EV charging services: recharge your car anywhere, anytime
Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.
Neuron Guard — Neuron Guard, recognized as the best European startup in HEALTH category (Startup Europe Awards - SEUA 2017), is developing a life-saving medical device that aims to become the standard of care for Targeted Temperature Management (TTM) therapy. Every 7 seconds around the world a person suffers of Acute Brain Damage because of CardiovascularDiseases (CVD) and Traumatic Brain Injury (TBI). They are the most costly and prevalent killers in the last 15 years (15 million deaths by CVD in 2015), and the leading cause of disability (the global incidence rate of TBI is 200 per 100k people per year). WHO estimated a global expenditure of $ 330 billion in 2015, but it is going to increase sharply: $ 4 trillion in 2025 - including premature death, disability, and health care costs - just for CVD in LMICs. Temperature is a vital body parameter. It regulates all cellular functions so its management is essential for the good outcome of patients in several medical conditions such as cardiac arrest, stroke, traumatic brain injury, neuro and cardiac surgery, epilepsy, migraine and oncology. Regulating body temperature at a desired level makes all other treatments more effective. The most modern medical approach is the target temperature management, where physicians try to maintain the most favourable temperature for the patient for up to 24-36 hours, preventing excessive warming (fever) or cooling.Our device is a targeted temperature management system composed by a THERAPEUTIC COLLAR POWERED BY A SMART CONTROL UNIT (the size of a small briefcase). The collar transforms the neck into a natural heat exchanger exploiting several physiological and anatomical characteristics of the human body. It is quicker to act on brain tissue but can also function as total body temperature adjusting device if required. A disposable protective shield makes cleaning the collar after each use simple while featuring an optimal safety profile both in term of pathogens and allergens. The control unit collects all the data of the treatment and transmits them to the Emergency Response System. Our mission is to improve the safety of patients on the roadside, at home or in the workplace, and to reduce the costs of chronic care. In fact, Neuron Guard aims to be the only device that can be used in every circumstance, inside and outside the hospital, and allow the user to fully manage the temperature of the patient warming and cooling as necessary. Our vision is to have a Neuron Guard kit in every public place just like the Automatic External Defibrillator (AED) to empower bystanders to immediately react in case of emergency. Under this perspective our device becomes a connected-intelligent platform that takes care of the patient, connects the scene with the Emergency Response System transmitting vital data to improve the readiness and effectiveness of professional intervention.The device is patented in Italy, USA and China. We have made several prototypes in collaboration with Italian and English companies, such as Tecno Elettra Impianti and TWI, tested it in laboratory and published the experimental results on the NeuroCritical Care Journal. We have also conducted a GAP Analysis with another English consulting firm (CDP) and we are testing the human prototype internally. We are seeking to raise 2.5M€ to complete the pre-industrialization, with design and construction of the human device for the pilot trial, finalized the regulatory clearance and launch it into the market in 2019.

Green Arrow Capital is an independent financial group specializing in alternative investments across Europe. They represent a one-of-a-kind platform, capable of connecting the financial system with the real economy through the management of private equity, private debt, infrastructure, and special credit situation funds as well as thematic fundssuch as microfinance and funds of funds that are currently under management. Their team has a successful track record in asset management, investment banking, industry sectors, technology startups, management consulting, renewable energy, and has government and regulatory experience. Their group is mainly composed of investment, asset management, and financial advisory companies. Their aim is to create a solid financial platform to launch and manage investment funds dedicated to alternatives and to the real economy.

Investment focus

Health Care, Biotechnology, Manufacturing
Funding Round, Seed, Series A
Italy, United Kingdom

Portfolio highlights

Cogisen — Cogisen develops artificial intelligence solutions. It offers SENCOGI, an eye-tracking software for smartphones/mobile phones. Chiara Passacantilli and Christiaan Erik Rijnders founded Cogisen in 2009. Its headquarters is in Naples in Italy.
Directa Plus — Directa Plus is a nanotechnology company, manufactures nanoparticles.
Glomeria Therapeutics — Glomeria Therapeutics researches, develops, and markets new medical devices for the treatment of serious diseases in the nephrological area. It offers DesmoPD, peritoneal dialysis connection system; SmartPD, an automated management device for peritoneal dialysis solutions to be instilled in peritoneum; and solutions for peritoneal dialysis.Andrea Zanella founded Glomeria Therapeutics in 2010. Its headquarters is in Chieti in Italy.

Club degli Investitori (Investors Club) is a network of investors and business angels that invest on early-stage SMEs and startups. The community of 300+ Members (entrepreneurs, CEOs, executive managers) actively scouts for investing opportunities on SMEs & startups and invests with a minimum ticket of €200k. The Club supports business byinvesting capital and by leveraging the Members' network and experience.Club degli Investitori is supported by Unicredit and KPMG Italy.

Investment focus

E-Commerce, Health Care, Software
Seed, Series A, Funding Round
Italy, United Kingdom, Israel

Portfolio highlights

Algor Education — Algor Lab is a company that provides tools and materials needed for teaching through artificial intelligence.
CarpeCarbon — CarpeCarbon is a company that develops technologies for Direct Air Capture (DAC) to extract CO2 directly from the atmosphere. Based in Italy, with a Global vision, the company is made of young researchers (Physics, Chemistry, Astrophysics, Biology, Complex Systems, Engineering) and economists.
ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.

Eureka! is the first independent Italian venture capital Asset Management company exclusively focused on deep tech investments

Investment focus

Nanotechnology, Renewable Energy, Medical Device
Funding Round, Seed, Pre-Seed
Italy

Portfolio highlights

Planckian — Charging the future by powering energy with science We explore frontiers of energy science by developing quantum...
INTA Systems — INTA Systems is a developer of lab-on-a-chip for biomolecular analysis through the combination of nanotech and artificial intelligence.
BeDimensional — We produce graphene and others two-dimensional materials (2D) with few atomic layers. Find out more.

CDP Venture Capital Sgr - National Innovation Fund aims to make venture capital a cornerstone of the country's economic development and innovation, creating the conditions for an overall and sustainable growth of the venture capital ecosystem.

Investment focus

Software, Health Care, Information Technology
Seed, Series A, Funding Round
Italy, United States, Germany

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
Voidless — VOIDLESS is the new generation of box-on-demand packaging. An innovative system that bets everything on reliability and integrability.
Daze — Discover Daze's innovative electric car charging systems. The only charging systems with integrated load balancing.

Claris Ventures is a venture capital firm supporting the best scientists in building successful life sciences companies that will impact people's lives

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
ALKemist Bio — ALKemist Bio provides cell treatment to cancer patients.
Repron Therapeutics — Repron Therapeutics provides treatments for solid tumor cases where radical excision is not possible and metastasis or recurrence is extremely likely.

Angel group focuses on biotech

Investment focus

Health Care, Biotechnology, Pharmaceutical
Seed
Italy

Portfolio highlights

MgShell — MgShell offers intraocular devices for the treatment of age-related macular degeneration and other ocular diseases. Their technology is the only technical solution capable of replicating current clinical practice with a single injection and releasing the same therapeutic drug doses at predetermined periods, autonomously and without surgicalprocedures.
CaSRevolution — A novel disease-modifying approach against neurodegeneration
Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
Pear Suite — Pear Suite enables anyone—community health workers, other healthcare staff, and volunteers—to assess and address the social drivers of health for older adults in a scalable, cost-effective, and person-centered way.
Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs

Helsinn Investment Fund S.A. is a Luxembourg fund focused on early-stage investments in areas of high unmet patient need.

Investment focus

Biotechnology, Medical, Biopharma
Series B, Series A, Funding Round
United States, Italy, United Kingdom

Portfolio highlights

NeoPhore — NeoPhore targets the dynamics of cancer neoantigen evolution and makes effective medicines that will become a key part of the next-generation of cancer immunotherapies.
Sibylla Biotech — Sibylla Biotech developed small molecule folding interfering degraders (FIDs) that can address a range of therapeutic areas.
On Target Laboratories — ON TARGET LABORATORIES discovers and develops fluorescent markers to target and illuminate cancer during surgery so it can be removed more completely.

European Investment Bank (EIB) provides lending, borrowing, and treasury services primarily in the European Union.The company offers project loans for the public and private sectors; loans to banks and other intermediaries; structured finance products; guarantees and securitization instruments for senior and subordinated debts; project bonds;equity and fund investment products such as infrastructure equity and debt funds, and environmental funds; and venture capital funds and security packages for funds.The company also offers microfinance; risk sharing finance for research, development, and innovation projects; finance and technical expertise for sustainable energy projects; infrastructure project advisory services; support for urban development projects; guarantees for transport infrastructure; and funding for public-private partnerships and small- and medium-sized enterprises.EIB serves the transportation, global loans, energy, industry, health, education, water, sewerage, infrastructure, services, telecommunications, agriculture, and fisheries sectors.European Investment Bank was founded in 1958 and is based in Luxembourg.

Investment focus

Biotechnology, Health Care, Software
Debt Financing, Post-IPO Debt, Funding Round
France, Germany, The Netherlands

Portfolio highlights

Eldrive — The largest charging point operator in Eastern Europe | Our network is expanding rapidly yet our focus is fixed on renewables, for a greener future. We provide AC & DC charging across Bulgaria, Romania and Lithuania.
ABN AMRO Bank — Als bank leggen wij de focus op inclusiviteit, duurzaamheid, sociaal ondernemen, innovatie, dagelijkse bankzaken en meer.
Enel Green Power — Enel Green Power is the company that deals with renewable energy from every perspective: from direct sales through PPA, to commitment at the forefront with its plants worldwide.

Investment fund specialized in sustainable technologies from universities and public research organizations, start-ups, spin-offs, and entrepreneurs.

Investment focus

Water, Eyewear, Farming
Seed, Pre-Seed, Series A
Italy, Ireland

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.
Valuematic — Valuematic realizza soluzioni per il trattamento e gestione dei dati favorendo il miglioramento nei processi organizzativi e informativi di aziende ed enti.
HT Materials Science — HT Materials Science provides nanofluid science in thermal systems for commercial and industrial infrastructure.

Lazio Innova is a venture capital firm with its headquarters in Rome in Italy. The firm provides services in areas such as credit support and guarantees, interventions in risk capital, internationalization services, promotion of business networks and services for the creation and enterprise development.

Investment focus

Health Care, Software, Artificial Intelligence
Seed, Pre-Seed, Grant
Italy, United Kingdom

Portfolio highlights

Joinrs — We developed an artificial intelligence model able to read job offers for you and show you the ones that best match your profile.
Medicud — Medicud develops a device for treating wounds with negative pressure dressing.
Ticketoo — Ticketoo: compra e vendi biglietti fan-to-fan in modo sicuro

INGENIUM Emilia Romagna was started with EUR 5.30 million by the Emilia Romagna region and EUR 1.7 million from fund managers. Managed by META Investment, the nine-year fund operated through the temporary acquisition of minority stakes in high-opportunity technological companies. It is now fully invested.

Investment focus

Medical, Health Care, Privacy
Seed, Angel, Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.
GreenBone Ortho — GreenBone Ortho was founded in Faenzato offer advanced and innovative solutions in the field of orthopaedics and bone regeneration, using the Rattan wood.
Angiodroid — Angiodroid srl, a medical technology company, focuses on hemodynamics, vascular surgery, and interventional radiology. It offers an automatic injection system for carbon dioxide angiography. Its products include carbon dioxide injector that is used as a contrast medium for pheriperal interventional angiography; and a single use kit, which iscomposed of French catheters and a custom connection line. The company is based in San Lazzaro di Savena, Italy.

Crédit Agricole Italia is a bank that offers loans and financial services.

Investment focus

Water, Farming, Software
Debt Financing, Seed
Italy

Portfolio highlights

Ecopol — The Ecopol's PVA water-soluble film technology is the world leading solution in packaging applications, such as detergents, agrochemicals, etc.
Finapp — Finapp is an innovative startup that produces a new generation of CRNS probes that allow measuring the water content. Water in the ground, then soil moisture, water out of the ground, then in the biomass, water in the snow, then snow water equivalent. The applications are really many, such as the research of water losses along aqueducts,hydrological and hydraulic modeling, estimates of hydroelectric energy but mainly agricultural ones.
Generalfinance — Generalfinance is a financial management agency that provides flexible services designed to address the company's debt issues.

Scopri i servizi bancari e finanziari di Banco BPM: conti, mutui, carte, prestiti, assicurazioni, trading e tanto altro. Per privati e imprese.

Investment focus

Manufacturing, Renewable Energy, Software
Debt Financing, Post-IPO Debt, Pre-Seed
Italy, Spain, United States

Portfolio highlights

3Sun — Our photovoltaic solutions drive change towards a sustainable future, setting new standards of excellence for solar energy applications.
Enel Green Power — Enel Green Power is the company that deals with renewable energy from every perspective: from direct sales through PPA, to commitment at the forefront with its plants worldwide.
Recupero Etico Sostenibile — RES specializes in waste management, environmental protection, and recycling services.

Angels 4 Impact is a Business Angel investment firm that invests in startups with innovative and technological content and a focus on impact.

Investment focus

Biotechnology, Manufacturing, Nanotechnology
Seed
Italy

Portfolio highlights

Diamante — Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.
Envirly — Envirly is a Polish technology company that offers an innovative platform for managing sustainable development, and the carbon footprint of organizations and products.

Oskare Capital is a venture capital firm.

Investment focus

Health Care, Biotechnology, Medical
Seed, Pre-Seed, Series A
Italy, Denmark, United Kingdom

Portfolio highlights

Leva Clinic — Leva Clinic offers health care services for people with chronic pain. Their medical services include back pain, cancer pain, endometriosis, facial pain, fibromyalgia, joint pain, knee pain, multiple sclerosis, sciatica, and so on.
Octarine Bio — Octarine Bio is a synthetic biology company that produces superior cannabinoids for the pharmaceutical industry.
Herbolea Biotech — Unique bio-processing technologies NATURAL, SOLVENT-LESS Botanical extraction Learn more

3LB Seed Capital is not an alternative to start-ups incubators and accelerators, rather acts as a complementary reality that helps to enhance your project in terms of attractiveness for the investor and venture capital market.As investors they are the first willing to know if your project has what it takes to grow successfully. If they areconvinced of your potential, they are ready to bet on you, by joining you and helping you to develop your project.3LB Seed Capital does not provide a percentage of equity in exchange for accompanying activities, but relies exclusively on a premium at the time of its first direct investment in your company.

Investment focus

E-Commerce, Information Technology, B2B
Seed
Italy

Portfolio highlights

Vikey — Self check-in Automatico e Domotica per Gestire da Remoto ogni aspetto dell'accoglienza in Hotel, Case Vacanze, Appartamenti e B&B.
YoAgents — YoAgents is a Digital Service company that allows sales professionals to connect with startups and micro-companies and SMEs.Through the app, they can choose services, pitch themselves to companies, download sales documents, create deals, with companies in the fitness, ho.re.ca., retail, sectors, as well as visualize and require revenue. Theplatform currently hosts over 2,000 sales professionals in its lead generation door to door platform.It was founded in 2016 and is headquartered in Milan, Italy.
Metis Precision Medicine — Metis Precision Medicine is a B-Corp founded with the vision of bringing powerful cancer therapies to patients in need. Metis owns the intellectual property of a suite of anti-Met monoclonal antibodies (mAbs), with different and unique mechanisms of action, and is currently seeking investors, biotech or pharmaceutical companies interested inacquiring the relevant platform technology on a global basis.

Sparta Capital Ltd. focuses on product development, manufacturing, distribution, sales and service across a range of technologies. The Company's offering includes four different market verticals: transportation, mining, construction and energy (through biomass conversion). These offerings include optimization of energy consumption in thecommercial and manufacturing sectors, construction and energy through biomass conversion, energy conservation in mining, and energy savings in transportation. It is focused on the expansion of a range of divisions, including photoluminescent safety products division, energy audit (EMD) division, biomass division and mining division.

Investment focus

Solar, Life Science, Biotechnology
Series A, Series B
Italy, Germany

Portfolio highlights

Sunvigo — Sunvigo provides you with cheap solar power from your roof and real green power from the grid.
GFBiochemicals — GFBiochemicals is the only company to produce levulinic acid derivatives at commercial scale directly from biomass.

Utopia is a venture capital firm that is dedicated to life sciences.Utopia SIS is an investment company specializing in healthcare and biomedical research, promoted and owned by the Golinelli Foundation.Utopia was established with the aim of bridging this gap, through investments in high-potential start-ups operating in the Life Sciencessector.

Investment focus

Health Care, Biotechnology, Pharmaceutical
Seed
Italy

Portfolio highlights

CaSRevolution — A novel disease-modifying approach against neurodegeneration

AbbVie is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories. The company's mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world's most complex and serious diseases. Togetherwith its wholly-owned subsidiary, Pharmacyclics, AbbVie employs ~29,000 people worldwide and markets medicines in more than 175 countries.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, China, Italy

Portfolio highlights

Mozart Therapeutics — The company intended to focus on developing novel immune engagers.
Quanta Therapeutics — Quanta is a biotechnology company uncovering novel cancer therapeutic candidates using allosteric modulation to target driver oncogenes. The company was founded in 2018 and is based in San Francisco, CA.
AmbAgon Therapeutics — AmbAgon Therapeutics is a developer of cancer molecule therapeutics. The company offers research of a small molecule that augments a tumor-suppressing protein. AmbAgon Therapeutics was founded by Christian Ottmann, Lucas Brunsveld, and Michelle Arkin.

We are an independent Venture Capitalfirm supporting visionary entrepreneurs toreinvent industries through technology.

Investment focus

Software, Financial Services, FinTech
Series A, Seed, Funding Round
Italy, United States, United Kingdom

Portfolio highlights

Fiscozen — Apertura partita IVA, fatturazione, F24, contributi, dichiarazione dei redditi. Tutto in un unico piano. Richiedi una consulenza gratuita.
Babaco Market — Babaco Market is a subscription with which you receive out-of-the-ordinary fruit and vegetables at home. Products that do not exceed the beauty contests organized by traditional channels and which risk being wasted. We deliver them to your home, in a box. Bring all the goodness of nature to the table and reduce food waste!
Electra Vehicles — Control, Analyze, & Design Innovative Battery Packs using Electra Vehicles' EVE-Ai 360 Adaptive Controls and Analytics and EnPower Design.

Panakes Partners is a venture capital investor that finances in medical companies, startups, and high growth SMEs in Europe and Israel. Advantages of the firm are broad network of business contacts and corporate relations, domain expertise, proactive portfolio management, and relationship with selected industrial partners. Investments of thecompany focus on medical devices, diagnostics, biotech for in-vitro diagnostics, IT healthcare, and medical services.Panakes Partners is an Italy-based company that was founded in 2015 by Alessio Beverina, Fabrizio Landi, and Diana Saraceni.

Investment focus

Health Care, Medical, Biotechnology
Series A, Series B, Seed
Italy, Ireland, France

Portfolio highlights

Allotex — Allotex offers therapeutic solutions for the treatment of presbyopia and hyperopia.
CarThera — Revolutionizing severe brain disease treatments
Neuromod Devices — Neuromod is a medical device company formed to advance the science of bi-modal neuromodulation.We are committed to delivering treatments that significantly reduce the suffering of underserved patient populations who live with chronic and debilitating conditions globally. Our goal is to design products that empower patients to take control oftheir own treatment, delivering targeted therapies that integrate seamlessly into a modern lifestyle.Neuromod has developed and patented a bi-modal neuromodulation technology that it is evaluating for neurological disorders including chronic tinnitus, a condition affecting 10% of the adult population and commonly known as 'ringing in the ears'.

Intesa Sanpaolo is a banking group that specializes in wealth management, protection, advisory, and digital orientation. Their products and services include accounts, cards, loans, mortgages, insurance, digital payments, retirement planning, investments, and consulting.

Investment focus

Financial Services, FinTech, Finance
Debt Financing, Post-IPO Debt, Seed
Italy, United Kingdom, United States

Portfolio highlights

Battistella — Battistella sells lumber, pine chips, sawdust, and pine logs. They serve both domestic and foreign markets. It exports its products worldwide. They engage in continuous recycling, which gives them the experience they need to satisfy the customs regulations of the various nations where they do business. They use the sawn pine wood that they processto make furniture and packaging.
Selene — Selene produces FFS tubulars, FFS films, preformed bags, stretch hoods, and technical films for industrial applications.
Goglio Group — Goglio Group produces full trademark food packaging.

Schia Ventures is investment firm.

Investment focus

Medical, Health Care, Biotechnology
Funding Round
Italy

Portfolio highlights

CellPly — Cellply is a life-science company focused on developing next-generation analytical tools enabling a deep characterization of cancer immunotherapies, cell therapies and cell-based biotherapeutics. The company aims to support the development of novel cancer immunotherapies by accelerating R&D, automating the quality control and advancing theability to monitor the clinical response to these treatments.Through the use of proprietary microfluidic technologies with Co-Culture Array technology, highly-automated analytical instruments and AI-powered image and data analytics, Cellply products define the function of the immune system one cell at a time, combining functional data with other multiplex data and providing unprecedented single-cell analytical solutions.

a|impact invests in the prevailing form of equity or quasi-equity, focusing our operations mainly on companies.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, United Kingdom, Canada

Portfolio highlights

Q32 Bio — Q32 Bio is developing drugs targeting powerful regulators of both the innate and adaptive immune systems with the goal of re-balancing the immune system.
Accent Therapeutics — Accent Therapeutics is a biopharmaceutical company developing oncology-focused, small molecule therapies in the emerging field of epitranscriptomics. This field of biology encompasses post-transcriptional chemical modifications of RNA that provide cells with a unique mechanism for regulating proteins critical for cellular growth anddifferentiation. By targeting cancer-linked RNA-modifying proteins (RMPs) with precision therapies, they aim to translate extraordinary science into life-changing therapies for patients.
Diagonal Therapeutics — Diagonal Therapeutics is a biotechnology startup that is pioneering a novel technique to finding and producing agonist antibodies. Diagonal Therapeutics platform combines novel computational and experimental methodologies to solve the traditional obstacles associated with agonist antibody drug development.

Powering Breakthroughs in Life Sciences

Investment focus

Biotechnology, Health Care, Pharmaceutical
Series B, Series A, Series C
United States, United Kingdom, Canada

Portfolio highlights

AstronauTx — AstronauTx is a UCL spin-off, will develop medicines designed to reset the behaviour of astrocytes.
Firefly Bio — Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.
Frontier Medicines — Frontier Medicines is boldly advancing science to defeat disease by pioneering innovations in precision-based medicines to target undruggable therapies

Estor is a Investment Firm.

Investment focus

Health Care, Biotechnology, Medical Device
Seed
Italy

Portfolio highlights

Endostart — Endostart development and manufacturing of a new generation medical devices for gastrointestinal endoscopy.

Seroba is a leading European life sciences venture capital firm focused on value creation through backing winning biotech innovations.

Investment focus

Health Care, Biotechnology, Medical
Series A, Series B, Funding Round
Ireland, United States, United Kingdom

Portfolio highlights

Shorla Pharma — Shorla Pharma is an Irish specialty pharmaceutical company. It is growing portfolio brings accessible, affordable and life-saving treatments to patients, delivering a major contribution to patient care and providing a significant clinical impact.
Storm Therapeutics — Targeting pathways that modify RNA to deliver novel cancer therapeutics.
Artica Therapeutics — Artica Therapeutics specializes in biotechnological research and development for medical devices, pharmaceutical processes, and food.

Siamo partner di private equity con una struttura family office. Selezioniamo start-up tech-driven con idee innovative e voglia di emergere.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.

Riso Gallo is a rice producer specializing in processing, and distributing of risotto rice to consumers around the world.

Investment focus

Portfolio highlights

MOGU — By employing one of its finest technologies, mycelium, Mogu delivers responsible products for interior design. Mycelium design with Mogu.

The official website of the European Commission, providing access to information about its political priorities, policies and services

Investment focus

Software, Health Care, Biotechnology
Grant, Seed, Pre-Seed
Spain, France, Germany

Portfolio highlights

SIMTEL Team — SIMTEL Team is a greenttech company that specializes in construction and maintenance of photovoltaic power plants.
SolarSpring — SolarSpring GmbH develops and produces pure water systems from clean materials. Thermal energy, photovoltaic (PV) energy, and energy gained from waste heat is used to promote water purification technologies such as membrane distillation and UV disinfection. The company's know how focuses on water purification systems operating based ondiscontinuous or minor energy sources.
Chemring Group — Chemring Group is a defense technology company engaged in the development and manufacture of countermeasures, sensors, and energetic systems for the aerospace, defense, and security markets. Its segments are countermeasures, sensors and energetic systems. The group has a product range including conventional flares, flares, special material decoys,chaff, and naval countermeasures. The group is also a contract research and development supplier. The company has four business units in North America supplying mainly to the US Department of Defense and its prime contractors seven businesses in Europe, supplying NATO and non-NATO customers and one business in Asia Pacific.

Lombardstreet Ventures operates as a pre-seed venture capital firm. It draws from talents around the world and fosters the creation of Silicon Valley Realities.The company consists of a team of seasoned executives works hand in hand with a small group of highly selected entrepreneurs. Expertise in funding and guidance is offered, to ensure thecreation of successful companies in the US.

Investment focus

Software, Information Technology, FinTech
Seed, Pre-Seed, Series A
United States, United Kingdom, Italy

Portfolio highlights

OpenPipe — Convert expensive LLM prompts into fast, cheap fine-tuned models.
Derisk — Derisk is a crypto custody infra and leverages Multi-Party Computation (MPC) cryptography.
Stellar Sleep — Stellar Sleep is a mobile app that helps you get better sleep using psychology. Stellar Sleep uses a combination of behavioral therapy, habit building social accountability, and gamification to create an enjoyable, yet clinically effective way for people to improve their sleep.

Angels4Women is a company that invests in business startups lead by females.

Investment focus

Retail, Fashion, Lingerie
Seed, Angel, Funding Round
Italy, United States

Portfolio highlights

Diamante — Diamante is a company that develops and manufactures autoimmune disease diagnosis devices using nanomaterials. It exploits plants as bioreactors for the sustainable production of nanoparticles based on modified plant viruses that are used in developing new tools. Diamante was founded in 2016 and is headquartered in Verona, Italy.
FUTURELY — FUTURELY is a platform which will help to choose university.
Chite Milano — Lingerie the Italian way. Discover 100% Made in Italy lingerie. Make your own: customise your lingerie and nightwear.

F3F

Investment focus

Hardware, Hospital, Software
Series A, Series C
Italy

Portfolio highlights

Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.
WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Milan-based Venture Builder specialised in AI & Blockchain

Investment focus

Software, Biometrics, Blockchain
Pre-Seed
Italy

Portfolio highlights

IIO — IIO is the open B2B2C VaaS (Voice-as-a-Service) platform that enables and improves the dialogue between people and devices through voice.It offers the possibility to create new applications through APIs and SDKs and allows to build new verticals in ecosystems that require a personal, close and secure experience.IIO Marketplace, will enablecollective intelligence to develop and share new “low / no-code” modular applications based on Voice (“VERSA”).Tech IP: Adaptive Conversational Engine (“A.C.E.”) allows you to adapt to the channel, emotions and discussion by managing exceptions with fall back logic;Conversational Editor, voice editing that will allow every developer to build and compose conversational applications: VERSAs.Secure Voice based on FoolFarm data “pulverization” patent, guarantees security and privacy of data, making users the owners of their information.A unique voice for your products and services: Proactive and dynamic It recognizes the speaker and intervenes only when necessaryIntuitive and empathetic Recognize emotions in words for personalized responsesContextual Always brings the flow back to the main topicMultichannel and Interoperable Manages handover on different channels and devices by integrating third-party services.Open and collaborative Expand the knowledge base thanks to the involvement of a Collective Intelligence.Low / No code Creation, modification, publication and use of new voice CX.
VoiceMe — SaaS solution of Voice Customer Authentication - a platform allowing electronic payments, single-sign-on and secured digital signing.

Scientifica Venture Capital offers private equity and venture capital investment services for Italy based startups and firms.

Investment focus

Medical, Biotechnology, Manufacturing
Seed, Private Equity
Italy

Portfolio highlights

Relicta — Relicta solution is a water-soluble bioplastic material obtained from fish processing waste and suitable for packaging solutions.
OhmSpace — OhmSpace provides the satellite market with reliable resistojets.
QuantaBrain — QuantaBrain purpose is to accelerate the diagnosis of psychiatric and neurodevelopmental diseases by applying artificial intelligence.

Launch Tennessee provides startup resources to entrepreneurs, including capital sources, mentorship, accelerators, entrepreneurship training and more

Investment focus

Software, Health Care, Medical
Grant, Seed, Series A
United States, China, Italy

Portfolio highlights

DAXOR — DAXOR Corporation is an innovative medical instrumentation and biotechnology company. DAXOR designed and developed the BVA-100 Blood Volume Analyzer. It is the first instrument approved by the FDA to provide rapid direct measurement of a patient's true blood volume. We believe that the BVA-100 Blood Volume Analyzer has the potential totransform therapy in a broad range of surgical and medical conditions. It is our goal, working in conjunction with hospitals and clinics, to achieve that possibility.The BVA-100 is a semi-automated Blood Volume Analyzer. It is used in conjunction with a single use diagnostic kit. It is the first FDA-approved instrument to provide rapid direct measurement of a patient's blood volume.
Preteckt — Preteckt's AI software predicts & prevents breakdowns in buses & coaches. Reduce costs, maximize uptime, & extend vehicle life
Branch Technology — Patented 3D-printed fabrication technology combining additive manufacturing, prefabrication, and digital technology at construction scale, with true design freedom.

Finalca is an Investment Company.

Investment focus

Medical, Health Care, Biotechnology
Seed
Italy

Portfolio highlights

GenomeUp — GenomeUp is an AI platform (SaaS) to enabling doctors and clinical institutions to diagnose and treat rare genetic diseases in less than 24h. GenomeUp is involved in international research projects and clinical trials in partnership with universities and research centers.

The JDRF T1D Fund (www.t1dfund.org) is a venture philanthropy fund exclusively devoted to finding and funding the best early-stage T1D commercial opportunities to accelerate the delivery of treatments, preventions, and cures to patients. It was created to solve a critical funding gap in the T1D drug and device development pipeline. Throughpartnerships with private capital, including venture capital, pharma and foundations, the T1D Fund anticipates that it will be able to attract substantially more private investment to the T1D field than occurs today. The T1D Fund will initially focus on artificial pancreas systems, metabolic control, beta cell replacement, prevention, and beta cell restoration therapies, with an exclusive priority on the best commercial opportunities. The T1D Fund will reinvest any realized gains into new investments to further its mission.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Funding Round
United States, Italy, Canada

Portfolio highlights

DiogenX — We incorporated DiogenX with the objective to provide new therapeutic solutions for diabetic patients. With Patrick Collombat and the team, we are focused on developing a first-in-class regenerative treatment for type 1 diabetes. Benjamin Charles CEO See the team News See more Our Work OUR APPROACH ABOUT DIABETES
Inversago Pharma — Inversago Pharma is a preclinical-stage, biotech company specialized in the development of new therapies focusing on CB1 blockade, based on first-in-class, peripherally-acting, CB1 inverse agonists.
Code Biotherapeutics — Code Biotherapeutics is an emerging next-generation gene therapy company pioneering the development of targeted non-viral gene therapies to treat serious and life-threatening genetic diseases not well served by other gene therapy technologies.

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