Top 20 Life Science VC Funds & Investors in Italy (June 2026)

Portfolio highlights

• protera — Protera is advancing the science of protein engineering to address some of the most critical problems and opportunities in food, agriculture, the environment and human health. We streamline protein design and development with MADI, our proprietary deep learning algorithm, to predict high value protein products and enzymes with unprecedented speed.Our in-house lab generates small quantities of the new predicted structures to validate their desired performance. Upon lab validation, we collaborate with our clients on next steps to move from pilot to industrial scale production.
• Bioptimus — Our mission is to build the first universal AI foundation model for biology to fuel breakthrough discoveries and accelerate innovations in biomedicine and beyond.
• T-Therapeutics — T-Therapeutics is a expertise in mouse genome engineering, deep expertise in biopharmaceutical drug development, single cell genomics, machine-learning and structural biology, anchored in a culture of creativity and collaboration. .

Portfolio highlights

• Dog Heroes — Dog Heroes delivers home recipes of fresh food, perfectly portioned to every dog's need. Only high-quality local ingredients are used in tailor-made portions that are ready to serve. Customers will find 55% meat of exclusively Italian origin in the company's recipes, balanced with vegetables, vitamins, and mineral salts. Dog Heroes doesnot use any chemical additives or preservatives.
• Streetbeat — Hedge fund level trading for everyone. StreetBeat’s solution is a combination of online brokerage and hybrid Robo-advisor with a significant edge on transforming data into actionable insight for casual and retail traders. Working with data from the most strategic providers, who currently serve the top hedge funds, we develop insights from creditcards, satellites, mobile GPS, app usage, and web browsing. We decode this information and make it actionable for everyone through our web application and an intuitive mobile app that can be easily used by experts and non-experts, reducing the information gap that exists between the average investor and Wall Street.At StreetBeat.com we are driven to give you a real-time view of the economy of the world with our 17 patent-pending software and the fastest signal on the market.Our algorithms individual stocks based on personalized characteristics of traders.https://youtu.be/pxwbSanXDRk
• ALLSIDES — Covision Media specializes in creating high-quality, relightable 3D models using their industrial 3D scanners. These scanners capture detailed surface information and PBR textures, and are designed for easy integration into virtual environments.

Portfolio highlights

• Easy Rain — Leading a new automotive era: our modular ecosystem of virtual sensors and active hardware makes cars and autonomous platforms truly safe in every condition.
• CamGraPhIC — Our platform supports the ever-increasing data traffic demand with high-performing and low-power consumption electro-optical engines.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

Portfolio highlights

• KLISBio — KLISBio is a medtech company currently developing a variety of regenerative medicine implantable products leveraging the power of silk fibroin to promote an endogenous repair of human soft tissues.
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• Lever Bio — Lever Bio's vision is to be at the forefront of unlocking groundbreaking advancements in biotech, particularly in the field of immuno-oncology. By fostering strategic collaborations with leading researchers, prestigious universities, and innovative research centers, Lever Bio aims to accelerate the development of cutting-edge therapies andtechnologies
• Sibylla Biotech — Sibylla Biotech developed small molecule folding interfering degraders (FIDs) that can address a range of therapeutic areas.
• Repron Therapeutics — Repron Therapeutics provides treatments for solid tumor cases where radical excision is not possible and metastasis or recurrence is extremely likely.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• CareGlance — CareGlance is the provider of real-time monitoring systems based on SS-OCT technology. Fast, precise and developed for the industry!
• Maieutical Labs — I Maieutical Labs sono un insieme di piattaforme ispirate al Mastery Learning, immersive e mobile-oriented, dedicate allo studio nella scuola secondaria
• Wearable Robotics — Wearable Robotics produces and develops wearable robotic systems and exoskeletons for rehabilitation, assistance and human-power augmentation.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...
• Recornea — Recornea is a developer of a corneal medical device to restore the physiological curvature of the cornea with clear and predictable clinical outcomes.
• Newronika — Newronika restores brain and body functions with innovative technologies. We translate our deep knowledge on biosignal decoding into clinical practice, with the aim of improving treatments, health, and wellness. With our revolutionary brain devices, the patient receives the right stimulation at the right moment, thus becoming able to perform normaldaily activities and improve quality of life. Newronika is the spin-off company of two leading research institutions in Italy, the Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Hospital and the University of Milan. ​ Newronika comprises a multidisciplinary team formed from Neuroscience research groups and involves scientists with expertise in neurophysiology, neurology, biomedical engineering, neuropsychology, bioinformatics, and biotechnologies.

Portfolio highlights

• Fyteko — For a more sustainable agriculture
• Ficosterra — fertilizers and bio-fertilizers, 100% vegetable and ecological, with algae and microorganisms that favor the maximum development of crops and plants.
• Hooked Foods — Leading the transition to a harmless seafood system by serving healthy vegan seafood for everybody to truly enjoy.

Portfolio highlights

• IMTherapeutics — Redefining Autoimmunity, Transforming Lives
• vTv Therapeutics — vTv Therapeutics, a pharmaceutical company, focuses on the discovery and development of human therapeutics to fill unmet medical needs. Its mission is to utilize its innovative technology to rapidly translate the functional modulation of human proteins into safe and effective medicines.vTv Therapeutics has a pipeline of small molecule clinicaland pre-clinical drug candidates for the treatment of a wide range of human diseases including central nervous system disorders, metabolic disorders, inflammation, and cancer. The company has built its product candidate portfolio through internal discovery and is advancing its product candidates through in-house research and development efforts. The quality and breadth of vTv's product candidate pipeline, platform technology, scientific team, and strategic collaborations have enabled it to become a fully integrated pharmaceutical company.The company's commitment to drug discovery is reflected in its medical solutions and the many exciting potential new treatment options in its pipeline. The company's major R&D activities have focused on central nervous system disorders, metabolic disorders, inflammation and oncology.vTv Therapeutics is advancing several proprietary drug candidates. The company's lead candidate, azeliragon (aka TTP488), is a novel, orally bioavailable small molecule compound that is being developed for the treatment of Alzheimer's disease. In Phase 2 clinical trial in patients with mild to moderate Alzheimer's disease, azeliragon showed a statistically significant difference of more than 3 points in ADAS-cog at 18 months compared to placebo.Azeliragon has been granted Fast Track Designation and agreement on its Phase 3 protocol has been reached with FDA via a Special Protocol Assessment (SPA). The Phase 3 study in patients with mild Alzheimer's disease was initiated in April 2015 with a clear path forward to registration with the aim to demonstrate disease modification.vTv Therapeutics is also prosecuting the clinical development of TTP399, a novel functionally liver-selective Glucokinase Activator ("GKA") for the treatment of type 2 diabetes. In a Phase 2a study, TTP399 normalized patients' HbA1c without inducing hypoglycemia, after only six weeks of treatment. A six-month Phase 2 study is ongoing.
• Veralox Therapeutics — Veralox Therapeutics develops small molecule therapeutics that treat the underlying pathologies of thrombosis and type one diabetes. Based on an understanding of the molecular mechanisms of these diseases, these efforts will lead to new treatment paradigms and better outcomes for patients.

Portfolio highlights

• Cato AI — Cato AI is a Milan-based B2B SaaS startup that uses AI to automate public tender management.
• Fitprime — Il Partner unico per il Wellbeing Aziendale
• Alomana —

Portfolio highlights

• Mozart Therapeutics — The company intended to focus on developing novel immune engagers.
• Quanta Therapeutics — Quanta is a biotechnology company uncovering novel cancer therapeutic candidates using allosteric modulation to target driver oncogenes. The company was founded in 2018 and is based in San Francisco, CA.
• DISCO Pharmaceuticals — DISCO Pharmaceuticals is a firm that specializes in large-scale surfaceome unlocking of cancer cells.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• Largix — Largix is the first company to develop and commercially produce 3D Robotic Printers for real production processes. We have invented the "Cold 3D Printing®" technology that makes 3DP possible for real industrial production. Largix uses the most common thermoplastic polymers: Polypropylene and Polyethylene, polymers that nobody else iscapable of printing.
• Spacest.com By Roomless — Rent directly online with Roomless, the safe and simple platform for those looking for a house for rent.
• Approxima — Approxima medical is developing a novel treatment for patients with tricuspid valve regurgitation

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — A deep understanding of customers let a company tailor marketing campaigns and CRM strategies, but companies have only basic data about customers (e.g. gender or age). External data sources like Social Networks, Public Registries and Socio-Demographic data contain rich information about billions of people, like job titles, levels of education,interests and habits.BigProfiles is a Customer Intelligence SAAS that leverages external information about persons to enrich customer profiling: it can profile a company's customers with previously unknown information about them. Thanks to its Identity Resolution algorithm (the result of a PHD), it identifies a person’s information scattered among external sources.Through this technology, BigProfiles provides customer base analytics and behavior predictions: using Artificial Intelligence on enriched profiles allows to predict churn, fraud and willingness to buy.
• Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Portfolio highlights

• Enthera — Enthera S.r.l. is a new Italian biotech start-up which mission is to find new therapeutic approaches to treat diabetes and related gastrointestinal complication (enteropathy), as well as other intestinal disorders sharing the same biological pathway. Its name comes from the crasis of the terms entero (referring to the intestine) and therapy.Enthera was founded by BiovelocITA in October 2016 in collaboration with the scientists: Prof. Paolo Fiorina and Dr. Francesca D’Addio.
• Arch Oncology — Formerly Known as Vasculox. Tioma is an immuno-oncology company developing anti-CD47 antibodies for the treatment of solid and hematologic cancers. The company's functionally diverse antibodies represent a new class of checkpoint inhibitors that harness both the adaptive and innate immune responses.
• Splice Bio — Splice Bio is a gene therapy company based on technology developed in the Muir Lab at Princeton University. The company is developing novel gene therapies based on its proprietary intein platform technology to treat patients that suffer from incurable genetic diseases. The company’s platform has the potential to address two existing limitations ofadeno-associated viruses (AAVs), both by increasing the size of the cargo gene that can be delivered and by expanding the range of tissues that can be targeted.

Portfolio highlights

• B-ON —
• Sunvigo — Sunvigo provides you with cheap solar power from your roof and real green power from the grid.
• GFBiochemicals — GFBiochemicals is the only company to produce levulinic acid at commercial scale directly from biomass.In 2008, a group of biobased chemical experts saw the significant potential of levulinic acid to replace petroleum-based products across a range of market sectors. GFBiochemicals was founded to develop the production technology needed for thisrevolution in chemicals and biofuels.GFBiochemicals demonstrated these breakthrough technologies in the Caserta plant, in partnership with the University of Pisa and the Polytechnic University of Milan. This commercial-scale plant was retrofitted with new conversion, recovery and purification technology.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.