Top 35 Life Science VC Funds & Investors in Italy (September 2026)

Portfolio highlights

• Odoo — From ERP to CRM, eCommerce and CMS. Download Odoo or use it in the cloud. Grow Your Business.
• Mironid — Google Analytics is a web analysis service provided by Google. Google utilizes the data collected to track and examine the use of www.mironid.com, to prepare reports on its activities and share them with other Google services. Google may use the data collected to contextualize and personalize the ads of its own advertising network.
• Forth Therapeutics — Forth Therapeutics is a biotechnology company dedicated to advancing precision treatments for fibrosis.

Portfolio highlights

• Mopso — Discover Mopso's anti money laundering detection system. Visit our website and try a 30 minutes free demo with one of our experts.
• Klaaryo — Klaaryo is the Conversational AI platform that helps organizations transform how they attract, hire, onboard, and develop their people.We design native AI Agents that communicate in natural language, understand people’s needs, and orchestrate complex HR processes in a simple, immediate, and scalable way.Our approach is WhatsApp-first, built toexpand into a multi-channel ecosystem that brings conversational intelligence everywhere people work, communicate, and interact.
• ExoLab Italia — Cosmetics Utilizing plant-derived exosomes in cosmetic products boosts skin absorption, enhancing bioavailability and stimulating cells to produce lacking compounds. Their ability to penetrate the dermis ensures maximum efficacy and optimal results for skincare products. more informations Supplements Plant-derived exosomes, rich in nutrients, enhance bioavailability by

Portfolio highlights

• Gility — Gility is a digital learning platform that collaborates with business schools and training institutions for an effective training offer. Established in 2022, it was supported by CDP Venture Capital and BPER Banca.
• Soplaya — Soplaya is a B2B food company connecting chefs and farmers to build a diverse, sustainable, and efficient food system.By providing data and transparency to an opaque supply chain, we help chefs to simplify purchases, get a wider selection of products and save money and farmers to increase their margins and get easy access to the market.We lovequality food as much as technology and automation. We are rebels: we love transparency and how the internet is capable of bringing the long tail to the market. We're excited about the fact that the restaurant supply chain hasn't basically changed since 40 years, and was technology reluctant for a long time, but restaurants necessities changed dramatically in the last 3 years.We’re becoming the standard layer for restaurant purchasing across Europe, by bringing transparency and simplicity in the procurement phase, increasing order frequency, promoting lean inventory and food waste reduction.
• Valvitalia SpA. — VALVITALIA is a leading group in the field of design, production, and overall supply of equipment and components intended for the petroleum, water, natural gas industries, and petrochemical industry as well as electrical power stations. The group works mainly with valves (core product), actuators, pipe fittings, flanges and systems for measuring,filtering, and regulating fluids and gases and with FireFighting systems. VALVITALIA was set up with the precise objective of becoming the leading Italian group able to offer such a wide range of products and to compete with the large American multinationals that have always dominated this field. This young company has extensive experience in the sector, thanks to its professional management and historical brands in the valve world that have been taken on by the Group, including: ROTOR, DELTA V.E., THEVIGNOT, VANADOUR, VITAS, TORMENE T.G.T. and TECNOFORGE. VALVITALIA has always included safety and respect for the environment and its employees among its priorities.

Portfolio highlights

• Newcleo — newcleo is the clean and safe nuclear technology company. Privately funded and headquartered in London, UK, newcleo was launched in 2021 to be a disruptor in the field of nuclear energy. Its mission is to generate safe, clean and inexhaustible energy for the world, through a radically innovative combination of existing, accessible technologies.newcleo is building the next generation system with the goals to: (1) eliminate the need for geological repositories by using a fast neutron flux avoiding production of long life radioactive elements; (2) develop an Accelerator Driven System (ADS), based on the intrinsically safe coupling of a particle accelerator and a sub-critical reactor; (3) accelerate the development of new fuel cycles, including thorium, that provide economic, clean, safe and inexhaustible energy from nuclei and the opportunity to burn the long-lived nuclear waste produced by the old generation of nuclear reactors.With visionary co-founders, newcleo brings together a team of engineers with deep knowledge of nuclear energy with younger recruits with a fresh mindset, working to design an innovative micro Lead Fast Reactor with significant commercial applications, for example in shipping. newcleo wants to be the first step toward the evolution of its industry to become fully respectful of people and the environment. To develop a new, sustainable, and completely safe way of generating nuclear energy that will lead humanity to zero emissions, and to the mitigation of global warming.
• Easy Rain — Leading a new automotive era: our modular ecosystem of virtual sensors and active hardware makes cars and autonomous platforms truly safe in every condition.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.

Portfolio highlights

• Soource — Soource is a B2B Saas product that uses AI applications to help purchasing managers to discover the best market solutions through extensive global research and automated email negotiations with thousands of suppliers worldwide.
• CiaoDott — Automatizza le telefonate, prenotazioni e FAQ del tuo studio medico con CiaoDott, l'assistente vocale AI disponibile 24/7. Provalo gratis.
• Quantum Bridge — Quantum Bridge is a pioneer in Distributed Symmetric Key Exchange (DSKE) technology. It offers quantum-safe cybersecurity products and services. Quantum-safe product and services, Quantum-safe roadmap and quantum-safe solutions implementation.

Portfolio highlights

• KLISBio — KLISBio is a clinical-stage regenerative medicine company focused on developing innovative technology platforms based entirely on natural silk fibroin. The company, headquartered in Milan, Italy, currently has several assets under development, such as vascular graft, bone graft substitutes, rotator cuff repair, drug release, and a first-in-humanstudy on nerve repair that is ongoing at the University of Zurich, Switzerland
• ENTEROME — We are a clinical stage biopharmaceutical company developing novel drugs to transform human health based on our unique ability to de-code molecular interactions in the gut microbiome.
• WISE — WISE (Wiringless Implantable Stretchable Electronics) is a start-up company created in 2011 with the mission of producing the new generation of leads for neuromodulation for treatment of chronic pain and Parkinson: unbreakable, less invasive and cheaper.

Portfolio highlights

• Lever Bio — Lever Bio aims to translate groundbreaking discoveries in immuno-oncology into next-generation cancer immunotherapies.
• Iama Therapeutics — At IAMA Therapeutics, we are constantly pushing the boundaries of neuroscience drug discovery to develop new medicines and make a difference in the lives of children suffering from brain disorders and their families. Our purpose is to provide a therapeutic solution to children suffering from neurological conditions and provide their families withthe support they need.
• Haptena Therapeutics — Haptena Therapeutics develops next-generation immunotherapies for oncogene-driven cancers, integrating precision oncology and immune engineering. Our research focuses on KRAS-mutant tumors to deliver more effective and durable treatment options.

Portfolio highlights

• Cato AI — Search, analyze and bid on Italian public tenders with AI, automating the manual work for bid offices and sales teams.
• AUDIOGEN — Generate your sounds with AI. Create an infinite world of sounds - sound effects, samples, and music, instantly. Get Started Free.
• Alomana — Autonomous systems for enterprise

Portfolio highlights

• Ecomate — The ESG Rating platform for every company
• BigProfiles — BigProfiles is an Artificial Intelligence Platform designed for Utilities, Telcos, Banks, Insurance companies and Retails.Large companies such as Teleperformance, Eni, Unicef already have already successfully subscribed to our services.BigProfiles is the No-Code Artificial Intelligence Platform for sales and antichurn that predicts thelikelihood to purchase and churn of each customer in a CRM, before proceeding to contact him in a sales or retention campaign.
• Codemotion — Codemotion is the ecosystem devoted to innovation, focused on developers and coding, open to all programming languages and technologies. Pioneering spirits, it scout the future to deliver a first class experience to our people. Codemotion is one of the biggest tech-conferences in Europe, with an international network of 30.000 developers and 350speakers coming from all over the world and from the most important IT realities.Codemotion draw in its main conferences, thousands of attendees eager to discuss about hottest topics: it tailor for them disruptive proposals ranging from mobile to UX, develops, cloud, big data, gamedev, security, methods, languages, web, Internet of things. Codemotion is also a startup, providing a bunch of services and activities, for personal and business customers.

Portfolio highlights

• CareGlance — CareGlance is the provider of real-time monitoring systems based on SS-OCT technology. Fast, precise and developed for the industry!
• Rainbow Crops — Rainbow Crops is a next-generation Agtech company developing climate-resilient, high-performing crop varieties.
• Wearable Robotics — Wearable Robotics produces and develops wearable robotic systems and exoskeletons for rehabilitation, assistance and human-power augmentation.

Portfolio highlights

• CellPly — Cellply offers an automated platform for functional precision medicine. We provide single-cell drug response profiling to guide oncology treatments...
• Recornea — Recornea is a developer of a corneal medical device to restore the physiological curvature of the cornea with clear and predictable clinical outcomes.
• Health Triage — Health Triage, crea nuove tecnologie per offrire modelli innovativi di diagnosi clinica, identificazione e cura delle malattie oncologiche.

Portfolio highlights

• K3RX — K3RX products for thermal protection systems of the next generation of hypersonic vehicles and rocket motor inserts of satellite launchers demonstrate their performance. K3RX manufactures tiles in uhtcmc material, rocket nozzles, screws, nuts, and support mechanical connectors.
• Eye2Drive — Eye2Drive designs bio-inspired, AI-ready CMOS image sensors for autonomous navigation, eliminating flickering and ghosting while significantly enhancing safety.
• Fluid Wire Robotics — A fully electric robotic platform for extreme environments: nuclear, space, cryogenic, ATEX and subsea. Manipulation where conventional robots cannot go.

Portfolio highlights

• CaSRevolution — A novel disease-modifying approach against neurodegeneration
• Lighthouse Biotech — Lighthouse Biotech offers a liquid biopsy tool that helps to extract live and intact circulating tumor cells from a simple blood sample, to avoid repetition with altered metabolism, helping medical staff and doctors to trace and treat tumor cells in the very early stages of the disease.

Portfolio highlights

• Mozart Therapeutics — The company intended to focus on developing novel immune engagers.
• Quanta Therapeutics — Quanta is a biotechnology company uncovering novel cancer therapeutic candidates using allosteric modulation to target driver oncogenes. The company was founded in 2018 and is based in San Francisco, CA.
• DISCO Pharmaceuticals — DISCO Pharmaceuticals is a firm that specializes in large-scale surfaceome unlocking of cancer cells.

Portfolio highlights

• GuRu — GuRu Wireless is adaptive, long-range wireless energy transfer. Anything that uses power can benefit from GuRu's wireless energy transfer technology. If you have an application, we have the technology.
• PteroDynamics — PteroDynamics in an aircraft manufacturer that builds ultra-long-range VTOL aircraft based on its Transwing aircraft design with folding wings
• Purple Style Labs — Purple Style Labs is an IIT-Bombay graduate and ex-banker with Deutsche. It aspires to be the biggest fashion house of India managing multiple designer brands in the premium, luxury as well as affordable retail segment.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• AveXis — Discover how Novartis Pharmaceuticals brings innovative medicines to market to enhance health outcomes for patients and offer solutions to healthcare providers.
• Mironid — Google Analytics is a web analysis service provided by Google. Google utilizes the data collected to track and examine the use of www.mironid.com, to prepare reports on its activities and share them with other Google services. Google may use the data collected to contextualize and personalize the ads of its own advertising network.
• Cour Pharmaceuticals Development — Reprogramming the immune system. Restoring lives.At COUR, we are developing targeted therapies that re-establish calm within the immune system and help rest ...

Portfolio highlights

• HEU — Draft, sign and store contracts in one place. AI extracts deadlines and clauses, signatures valid in 180+ countries.
• Tech4All — We support the study by using AI.
• GeneSys Bio — Antimicrobial Resistance (AMR) is a global health emergency projected to cause 10 million deaths annually by 2050. The crisis is fueled by slow, conventional diagnostics that take 3-5 days, forcing the empirical use of broad-spectrum antibiotics and accelerating the spread of superbugs.GeneSys Bio is commercialising a breakthrough solution: afully automated, sample-to-result molecular diagnostic platform that identifies infectious pathogens and their critical antibiotic resistance genes in under 30 minutes with >99% sensitivity and specificity. Our portable, laptop-sized device combines proprietary nucleic acid amplification with an AI-driven engine to deliver clear, actionable results directly to clinicians, veterinarians, and public health officials.Our platform is a modular "One Health" solution, adaptable via disease-specific kits for human, veterinary, and environmental applications. We are entering the market with a diagnostic for Urinary Tract Infections (UTIs), a condition affecting over 500 million people annually and a primary driver of antibiotic misuse. By enabling targeted therapy at the first patient encounter, our platform is set to reduce treatment costs by up to 13%, cut follow-up visits, and decrease mortality from complicated infections by 50%.GeneSys Bio is positioned to capture a significant share of this market by bridging the critical gap between speed, laboratory-grade accuracy, and accessibility. We are not just creating a device; we are building the future of decentralized infectious disease diagnostics to safeguard global health for generations to come

Portfolio highlights

• Alomana — Autonomous systems for enterprise

Portfolio highlights

• Aflabox — Aflabox develops food contaminant detection devices utilizing NIR spectroscopy and advanced image processing that uses AI analysis.
• Yeastime — Discover how ultrasound can improve the fermentation process by up to 30% with our innovative solutions.
• VisioNing — VisioNing is a cleantech company that offers proprietary technology solutions for treatment and valorization of agro-industrial wastewater.

Portfolio highlights

• Aflabox — Aflabox develops food contaminant detection devices utilizing NIR spectroscopy and advanced image processing that uses AI analysis.
• Yeastime — Discover how ultrasound can improve the fermentation process by up to 30% with our innovative solutions.
• VisioNing — VisioNing is a cleantech company that offers proprietary technology solutions for treatment and valorization of agro-industrial wastewater.

Portfolio highlights

• Zag Bio — Zag Bio is harnessing the immune system in a whole new way by targeting the thymus to change treatment possibilities for millions of patients with autoimmune diseases.
• Endlyz Therapeutics — ndLyz Therapeutics, Inc. is developing disease-modifying therapeutics which restore endo-lysosomal function and abrogate neurodegeneration in Parkinson’s disease (PD) and other dementias.
• DISCO Pharmaceuticals — DISCO Pharmaceuticals is a firm that specializes in large-scale surfaceome unlocking of cancer cells.

Portfolio highlights

• Wikicasa — Scegli tra migliaia di annunci di case in vendita completi, aggiornati e affidabili. Per trovare velocemente la tua futura casa con Wikicasa!
• React4life — React4life is an Italian biotech company founded in 2016 after more than 15 years of R&D by Silvia Scaglione and Maurizio Aiello, together with a multidisciplinary team of experts, with the ambition to turn the promise of biomedical research into concrete benefits for society. Scientists can finally rely on a new enabling technology torecapitulate human biology in the lab: MIVO® (Multi In Vitro Organ), the next generation of organ-on-a-chip. This cutting-edge microphysiological system enables researchers to overcome the limits of current in vitro assays and animal models. It improves the reliability and predictivity of several applications: pharmaceutical drug-testing, personalized medicine, novel immuno-oncology therapies, cosmetics, dermatology, and nutraceutical. Learn more at www.react4life.com
• greenchic — A pioneer of the circular economy, greenchic is the number 1 fashion-logistics startup in Southern Europe. Send us what you wish to swap, and immediately start buying with our reward points system. Thanks to this effortless service model, greenchic offers the fastest DTC way to regain value from no longer used clothing. Through greenchic, memberscan exchange items and revamp their style in an affordable, convenient and sustainable way. With 99% of the products sold, reused, upcycled, or donated to charities within 6 months, greenchic is set to become a European leader in circular fashion. With its growing user base, the highest customer retention rate in fashion recommerce, a 4.5-star TrustPilot rating, the platform offers to its highly engaged community a collection of more than 240.000 items. Thanks to a semi-automated logistic warehouse, an event-driven serverless digital platform, and its own digital token, the startup is experiencing a 2X growth pattern and is supported by some of the best investors from the Italian fashion & social impact scene.greenchic is now operating in Italy and France.Find out more by visiting greenchic.com and following @greenchic on socials.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• Kokomodo — Kokomodo is a produce cocoa via plant cell culture. Kokomodo cellular agriculture technology produce real, controlled, climate-resilient cacao, everywhere, year-round.
• Hooked Foods — Hooked Foods is working on a plant-based tuna substitute. By serving delicious plant-based seafood for everyone to enjoy, the company is leading the transition to a healthier seafood ecosystem. The company was established in 2019 and is headquartered in Sweden.
• ProSeed Ingredients — ProSeed Ingredients SA develops plant-based ingredients from seed side streams for food and nutrition brands. The portfolio includes protein concentrates, fibers, and functional flours processed from oilseed press cakes and other by-products. These ingredients support applications in bakery, snacks, beverages, dairy alternatives, and meat analogsthrough water binding, emulsification, and texture control. The company offers application trials, prototyping, and co-development to adapt functional performance to specific recipes. Quality and regulatory services include specification sheets, traceability, allergen management, and consistent lot-to-lot performance. Sampling, pilot runs, and scale-up guidance help R&D and procurement teams evaluate and integrate the ingredients into existing production.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• Cellex — Cellex, an innovative Small and Medium Enterprise (SME) founded in 2018, specializes in designing and manufacturing advanced bioreactors for cell culture, as well as developing state-of-the-art digital twin software for bioprocesses. Headquartered in Rome, with a subsidiary in Wageningen, Netherlands, Cellex is entering the scale-up phase aftersecuring multiple grants and raising capital from investors. With a solid foothold in the biotech industry, Cellex aims to revolutionize the production of cell-derived drugs, cultivated meat, and tissue engineering through its innovative hardware and software solutions.Key Products • SUSPENCE®®: A patented suspension bioreactor designed for cell culture with high efficiency and reduced operational costs. • BioAxFlow: A multi-tissue bioreactor aimed at tissue engineering and cultivated meat production. • BioDigiTwin: A digital twin software that simulates and optimizes bioprocesses, automating control and enhancing productivity.Markets and Target Segments • Biopharmaceuticals: SUSPENCE® bioreactors to produce vaccines and monoclonal antibodies. • Tissue Engineering: BioAxFlow bioreactors for tissue substitutes, in vitro tissue models, cultivated meat, and other applications. • Digital Twins for Bioprocesses: BioDigiTwin for real-time control and cost optimization of bioprocesses.
• Carne Genuina — Carne Genuina enables customers to order meat directly from particular breeders and have it delivered to their homes by a frozen courier.
• Socopet — Socopet S.r.l. is specialized in the production of PET-blown packaging. They produce products that are recyclable, recycled, biodegradable, and compostable. They manage to combine an oxygen barrier with thermal resistance, making it an alternative to glass and other less recyclable materials in the food market.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• Enthera — Enthera S.r.l. is a new Italian biotech start-up which mission is to find new therapeutic approaches to treat diabetes and related gastrointestinal complication (enteropathy), as well as other intestinal disorders sharing the same biological pathway. Its name comes from the crasis of the terms entero (referring to the intestine) and therapy.Enthera was founded by BiovelocITA in October 2016 in collaboration with the scientists: Prof. Paolo Fiorina and Dr. Francesca D’Addio.

Portfolio highlights

• Enthera — Enthera S.r.l. is a new Italian biotech start-up which mission is to find new therapeutic approaches to treat diabetes and related gastrointestinal complication (enteropathy), as well as other intestinal disorders sharing the same biological pathway. Its name comes from the crasis of the terms entero (referring to the intestine) and therapy.Enthera was founded by BiovelocITA in October 2016 in collaboration with the scientists: Prof. Paolo Fiorina and Dr. Francesca D’Addio.

Portfolio highlights

• Bio4Dreams — Il primo incubatore italiano certificato di startup innovative in fase very early stage, a capitale totalmente privato, dedicato alle Scienze della Vita.

Portfolio highlights

• Biorfarm — Adotta il tuo Albero, crea il tuo Campo Digitale e ricevi a domicilio la tua frutta biologica. Solo con Biorfarm puoi seguire la crescita dei tuoi frutti!
• EvenFi — Criptalia uses blockchain technology to connect businesses that have projects to be funded with people and organizations who are looking for high-yield investments. We offer an online platform where companies publish their innovative ideas and industrial improvement projects. Investors, people, and institutions can fund these projects by lendingmoney in exchange for a higher interest rate.
• Latitudo40 — Empower sustainable growth with AI-driven satellite insights from Latitudo 40. Unlock precise, real-time data for smarter urban planning, climate risk management, and industry innovation. Enhance resilience and lead with confidence.

Portfolio highlights

• B-ON — B—ON is a full-service solution provider democratizing fleet electrification, providing access to an entire ecosystem of services through one simple process. B—ON is focused on transforming last mile transportation of people and goods to zero emissions. B—ON was established in 2021.
• Sunvigo — Sunvigo provides you with cheap solar power from your roof and real green power from the grid.
• GFBiochemicals — GFBiochemicals is the only company to produce levulinic acid at commercial scale directly from biomass.In 2008, a group of biobased chemical experts saw the significant potential of levulinic acid to replace petroleum-based products across a range of market sectors. GFBiochemicals was founded to develop the production technology needed for thisrevolution in chemicals and biofuels.GFBiochemicals demonstrated these breakthrough technologies in the Caserta plant, in partnership with the University of Pisa and the Polytechnic University of Milan. This commercial-scale plant was retrofitted with new conversion, recovery and purification technology.

Portfolio highlights

• Genoa Instruments — Genoa Instruments is an innovative startup dedicated to transforming the field of biomedical and health research through advanced super-resolution optical microscopy. Our groundbreaking optical microscope uniquely integrates spatial and temporal super-resolution for structural and functional imaging in living samples with unprecedented detail. Ourmission is to make high-resolution imaging accessible to all, fostering scientific discovery and advancing healthcare research.

Portfolio highlights

• Zag Bio — Zag Bio is harnessing the immune system in a whole new way by targeting the thymus to change treatment possibilities for millions of patients with autoimmune diseases.
• Tetragenetics — Our protein production platform provides recombinant transmembane proteins, including ion channels and GPCRs, for antibody drug discovery
• vTv Therapeutics — vTv Therapeutics, a pharmaceutical company, focuses on the discovery and development of human therapeutics to fill unmet medical needs. Its mission is to utilize its innovative technology to rapidly translate the functional modulation of human proteins into safe and effective medicines.vTv Therapeutics has a pipeline of small molecule clinicaland pre-clinical drug candidates for the treatment of a wide range of human diseases including central nervous system disorders, metabolic disorders, inflammation, and cancer. The company has built its product candidate portfolio through internal discovery and is advancing its product candidates through in-house research and development efforts. The quality and breadth of vTv's product candidate pipeline, platform technology, scientific team, and strategic collaborations have enabled it to become a fully integrated pharmaceutical company.The company's commitment to drug discovery is reflected in its medical solutions and the many exciting potential new treatment options in its pipeline. The company's major R&D activities have focused on central nervous system disorders, metabolic disorders, inflammation and oncology.vTv Therapeutics is advancing several proprietary drug candidates. The company's lead candidate, azeliragon (aka TTP488), is a novel, orally bioavailable small molecule compound that is being developed for the treatment of Alzheimer's disease. In Phase 2 clinical trial in patients with mild to moderate Alzheimer's disease, azeliragon showed a statistically significant difference of more than 3 points in ADAS-cog at 18 months compared to placebo.Azeliragon has been granted Fast Track Designation and agreement on its Phase 3 protocol has been reached with FDA via a Special Protocol Assessment (SPA). The Phase 3 study in patients with mild Alzheimer's disease was initiated in April 2015 with a clear path forward to registration with the aim to demonstrate disease modification.vTv Therapeutics is also prosecuting the clinical development of TTP399, a novel functionally liver-selective Glucokinase Activator ("GKA") for the treatment of type 2 diabetes. In a Phase 2a study, TTP399 normalized patients' HbA1c without inducing hypoglycemia, after only six weeks of treatment. A six-month Phase 2 study is ongoing.