Top 50 Medical Device VC Funds in United States

Investor	Medical Device United States investments
Innova Memphis	71
Broadview Ventures	19
Portfolia	19
HealthTech Capital	18
CincyTech	18
MB Venture Partners	16
Good Growth Capital	16
Texas HALO Fund	15
TEDCO	15
Boston Harbor Angels	15
Oxford Finance LLC	15
New Enterprise Associates	14
Wavemaker 360	14
Maine Angels	14
Connecticut Innovations	14
Oxford Bioscience Partners	13
Arboretum Ventures	13
North Coast Ventures	13
Ben Franklin Technology Partners of Southeastern Pennsylvania	13
U.S. Venture Partners	13
Horizon Technology Finance	13
Khosla Ventures	13
Sand Hill Angels	12
Canaan Partners	12
Delphi Ventures	12
Catalyst Health Ventures	12
Versant Ventures	12
Catalyst Health Ventures	12
Wisconsin Investment Partners	12
Kleiner Perkins	11
Gaingels	11
Tech Coast Angels	11
Split Rock Partners	11
Houston Angel Network	11
Third Rock Ventures	10
DeNovo Ventures	10
Life Science Angels	10
Shangbay Capital	10
St. Louis Arch Angels	10
Silicon Valley Bank	10
Green Park & Golf Ventures	10
Rev1 Ventures	10
Morgenthaler Ventures	10
Three Arch Partners	10
Virginia Venture Partners	10
Hatteras Venture Partners	9
Sante Ventures	9
Mayo Clinic	9
Keiretsu Capital	9
Cherrystone Angel Group	9

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Convertible Note
United States, Argentina, United Kingdom

Portfolio highlights

Rantizo — Fly more acres, deliver better service. The equipment, tools, and expertise you need to be the grower's first call for drone spray services.
iYOTAH Solutions — iYOTAH Solutions is a transformational SaaS technology company that connects data to help the animal protein industry thrive.
Glanris — Glanris developed a completely green, non-toxic, filtration media for water purification from an agriculture by-product. This agricultural product is grown around the world, is plentiful, and can be used locally to ensure clean drinking water in developing countries. It also gives local farmers a significant additional income source for a productthat today they are throwing away.This media has been independently tested over the last two years of development and is ready for production.

Broadview Ventures, Inc. (Broadview) was established in 2008 as a new program conceived by the Leducq family. Through Broadview, the trust will work to accelerate the development of promising technology in cardiovascular and neurovascular disease through targeted investment in and support of early stage technology ventures.The FoundationLeducq, based in Paris, France, is the beneficiary of a charitable trust. In order to further the Foundation Leducq's mission in cardiovascular and neurovascular disease, the trust has made funds available to Broadview to develop a program which will promote early state technology in these fields through investments, licensing agreements and consortium funding arrangements, as well as professional, management and consulting support.With this initiative the trust joins other leaders in the venture philanthropy movement in seeking creative solutions to the problem of what is commonly referred to as the 'translational gap', a significant component of which is a lack of funding at a critical moment in the development of new technology and science.

Investment focus

Health Care, Biotechnology, Medical Device
Series A, Seed, Debt Financing
United States, Israel, Denmark

Portfolio highlights

IsomAb — IsomAb evaluate and develop isoform specific antibodies to treat disease.
Nyra Medical — MitraPlug has created a catheter-plug technology for repairing a leaky mitral valve in the heart.This adjustable device needs only a two-inch surgical incision and can be inserted directly into the heart. Then the cardiologist can use the catheter to adjust the size and position of the plug to correct the leakage. When correctly fitted, thecatheter is removed, and the incision is closed, leaving only a small scar.
Cardiosense — Cardiosense offers a physiological waveform AI platform to develop predictive biomarkers for the detection and treatment of disease. Its platform leverages multi-modal sensors and industry-leading AI to develop predictive biomarkers for the detection and treatment of disease.

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Series B
United States, Canada, Argentina

Portfolio highlights

Attn: Grace — Attn: Grace is a sustainable wellness brand designed for women. Starting with bladder leakage, they're creating thoughtful, more sustainable solutions for life’s inconvenient truths, one challenge at a time.
Prime Roots — Prime Roots is on a mission to provide a better cut of meat for every type of eater. Rooted in koji, Prime Roots is able to replicate the taste and texture of meat without any of the environmental costs of animal proteins.
Harvest Thermal — We are manufacturers of the cleanest home energy solution on the market today. We offer a cloud-enabled, ultra-clean heating, cooling and hot water system for residential customers. The brains of the system is our award-winning Harvest Pod that slashes carbon emissions, saves on utility bills, and

Private angel investors and corporate venture ecosystem investing in healthtech, digital health and other healthcare technologies startups

Investment focus

Health Care, Medical Device, Medical
Seed, Series A, Convertible Note
United States

Portfolio highlights

SafKan Health — OtoSet® by SafKan Health is the first FDA Cleared automated ear cleaning device for the 35 million Americans affected by impacted earwax - the leading cause of conductive hearing loss.
GT Metabolic Solutions — GT Metabolic Solutions has developed minimally-invasive incisionless bypass technology for bariatric, metabolic and digestive surgery.
Wavely Diagnostics — Wavely Diagnostics is pioneering the future of remote digital diagnostics and enabling telehealth growth by leveraging smartphone technology to address pediatric care.

CincyTech is one of the Midwest's most active seed funds, investing in disruptive human health and technology companies in Ohio.

Investment focus

Software, Health Care, Biotechnology
Seed, Series A, Series B
United States

Portfolio highlights

Amify — We help brands selling on Amazon maximize sales and profitability by providing complete strategy, management and operational services.
Invirsa — Invirsa is developing a unique, broad platform based on a naturally occurring small molecule (INV-102) that has demonstrated enhanced immune response to infection. INV-102 not only reduces viral infection, and potentially bacterial replication, it also reduces inflammation, while enhancing the bodies wound healing response. Invirsa'stechnology is first being developed in the ophthalmology and pulmonary space.Invirsa’s technology has the potential to be a first line therapy for common infectious diseases, whether it's the 100 million viral pulmonary infections or the 5 million infectious conjunctivitis cases that occur every year in the US alone.
Voxel — Voxel utilizes advanced mathematics and artificial intelligence to rapidly generate functionally graded meta-materials for high performance applications through additive manufacturing. We provides performance leaps in the defence, automotive, aerospace, medical, industrial, and other demanding areas and unlock new capabilities for our customers.

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Good Growth Capital provides investors with exceptional returns through our ability to source, assess and invest in early-stage transformative science- and technology-based companies in life sciences, data sciences, and greentech/hard sciences.

Investment focus

Health Care, Information Technology, Software
Seed, Series A, Convertible Note
United States, France, Israel

Portfolio highlights

Pienso — Pienso is a machine learning platform for non-programmers. Pienso’s end to end Intelligent Development Environment allows non-programming experts to create and train their own machine learning models without the need for external support. Founded in 2016 by Birago Jones, CEO and Karthik Dinakar PH.D, CTO. Pienso is headquartered in the BrooklynNavy Yard’s New Lab in Brooklyn, New York. For more information visit: http://pienso.com/ and follow @Pienso_ML.
Next Power 360 — NextPower360 offers the most advanced generator in the world for variable input and output applications such as wind power and electric vehicles.
Base Operations — Base Operations aggregates and visualizes threat data to help companies keep their people and operations safe around the world.

Early Stage Venture Investments

Investment focus

Health Care, Medical Device, Software
Seed, Convertible Note, Series A
United States, Canada, Hungary

Portfolio highlights

Flourish Collective — FlourishFund is a digital platform that empowers and supports new and expecting families. The platform consists of two parts: a marketplace with evidence-based goods and vetted maternal wellness services and a funding mechanism for friends and families to contribute to a positive birth and parenting journey.
Drusolv Therapeutics — Drusolv Therapeutics is a clinical-stage drug company developing a novel, high-dose statin for early intervention in age-related macular degeneration. Their product ocustatin is aimed at patients who are still in the intermediate stage of the disease and currently have very limited options to prevent progression to late-stage vision loss. Ocustatinwas developed at Harvard University and has been validated in a very successful proof-of-concept clinical trial that showed a 75% reduction in progression to late-stage blindness. John Edwards, the founder and CEO of Drusolv, is a serial entrepreneur with extensive experience in AMD.
Vartega — Vartega is a technology development company specializing in the carbon fiber-reinforced plastic recycling process. We have developed alternative technology, processes, and equipment to provide low-cost carbon fiber for use in mass market applications.

TEDCO was created by the Maryland State Legislature in 1998 to facilitate the transfer and commercialization of technology from Maryland’s research universities and federal labs into the marketplace and to assist in the creation and growth of technology-based businesses in all regions of the State. TEDCO is an independent organization thatstrives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy. In Maryland and beyond, TEDCO is a resource of mentoring, funding and networking for entrepreneurs and start-ups that need guidance as they bring innovative concepts to market. TEDCO is more than an early stage funding resource. It is the hub of Maryland’s entrepreneurial network where startups find mentors, organizational assistance, facilities for daily operations, and a roadmap for success.

Investment focus

Software, Health Care, Information Technology
Seed, Pre-Seed, Grant
United States

Portfolio highlights

ReBokeh — Simply Seeing Designed to Enhance Vision, Not Overpower it.The ReBokeh app was designed with moderate vision impairment in mind.Create custom video filters, unique to you and your environment - simply see the world how you want to. Get it Now! AS SEEN ON Our vision at ReBokeh is to make it simple for all individuals to
PediaMetrix — Founded by alumni entrepreneurs and scientists from Johns Hopkins, NIH, and Oxford, PediaMetrix’s mission is to bring AI and computer vision to pediatrics to lower the healthcare costs and improve outcomes. PediaMetrix’s lead product, SoftSpot, enables early detection and management of the most common conditions with head shape abnormalities innewborns. PediaMetrix is a Delaware company founded in 2018.
Escalate USA — At Escalate, we solve the talent crisis for retail corporations. We increase employee retention and the internal pool of skilled middle-wage candidates by providing frontline workers with weekly asynchronous online training that leads to industry-recognized certifications and upward mobility.

Boston Harbor Angels is a group of proven business leaders interested in investing a portion of their assets in high growth, early stage companies. The group was formed in February 2004 and since then has made a number of investments in companies in medical devices, IT, consumer products, business products, specialty materials, Internet, aviation,etc. They believe they contribute more than money to the companies they fund and welcome the opportunity to work with entrepreneurs open to take advice, yet having the smarts and determination to make the company successful.Their focus is on early stage companies usually looking to raise $250K to $1.5M, where they can fund a portion of the round and syndicate the deal with other angel groups or early stage venture funds. The stage of the company should be close to commercialization, while the company should have a clear and defensible competitive advantage. They are looking for capital efficient businesses, which can reach profitability with less than $5M of equity investment and provide at least 10X return on the investment within 5 years.They do not invest as a fund - each of their members makes his or her individual investment decision but they collaborate in Due Diligence. They have a deep expertise in the life sciences field where they usually take the position of a lead investor, but are open to any opportunities that can make a strong business case. In some cases they prefer to be the follow on investor if they cannot identify a person with strong expertise within their group.The groupâ€™s strategy is directed by an executive committee which consists of 8 people elected by the group: Wayne Griffith (chairman), Bill McPhee, Henry Kay, Jay Schwartz (membership director), Steve Andress, Peter Miller, Don Freeman and Mic Williams (president and founder). The groupâ€™s day-to-day operations are managed by Boris Batchvarov (managing director).They receive 20-30 business summaries each month, out of which they select 8 companies to make a personal presentation to their screening committee. The screening committee consists of volunteers from the group. The presentations are 10 min long followed by 10 min Q&A. 4 of the companies are invited to present to the whole group, with the idea to get the people interested and decide to perform a Due Diligence with the companies before making an investment.

Investment focus

Biotechnology, Health Care, Medical Device
Angel, Seed, Series A
United States, Canada, India

Portfolio highlights

Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
Xeno Biosciences — Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.It wasfounded in 2015 and is headquartered in Somerville, Massachusetts.
Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.

Providing Flexible and Creative Financial Solutions to Life Sciences and Healthcare Services Companies.

Investment focus

Biotechnology, Health Care, Medical
Debt Financing, Post-IPO Debt, Series B
United States, United Kingdom, Canada

Portfolio highlights

Amino — Amino's digital healthcare guidance platform provides a fast, easy way to find a doctor, book appointments, and access health benefits.
Headspace — Live a healthier, happier, more well-rested life in just a few minutes a day with the Headspace app.
Pearl Street Dental Management — Pearl Street Dental Management supports non-clinical operations. They provide centralized services such as human resources, payroll, accounting, bookkeeping, finance, lending, facilities management, and information technology services. They address inquiries through online applications, phone calls, and emails.

Foundational partners to ambitious founders at every stage of company-building.

Investment focus

Software, Health Care, Biotechnology
Series B, Series A, Series C
United States, India, China

Portfolio highlights

Wonder — Introducing a new kind of home dining experience. Currently available in areas of New Jersey.
Foundry — Elastic cloud infrastructure built for machine learning.
Avenzo Therapeutics — Developing the next generation of oncology therapies for patients.

Wavemaker Three-Sixty Health is the leading U.S. early-stage (Seed and following on at the Series A) venture capital fund focused 100% on healthcare. Launched in 2018, Wavemaker 360 invested into the most promising healthcare startups in North America, with LPs from every sector of the US healthcare system. We are SEEDING HEALTHCARE'STOMORROW. We invest in healthcare disruptors and entrepreneurs that see how the industry is transforming itself and want to make a big difference.

Investment focus

Health Care, Medical, Medical Device
Seed, Series A, Funding Round
United States, United Kingdom, Canada

Portfolio highlights

Elektra Health — Evidence-based menopause expertise & care because you deserve better
Pear Bio — Pear Bio uses organ-on-a-chip and computer vision technology to recreate, visualize, and compute the human tumor microenvironment and its effects on cancer progression. The company was founded in 2017 and is headquartered in London.
Nest Collaborative — Nest Collaborative offers online lactation consults. Virtual appointments are available same-day & are covered in full by most insurance plans.

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

Investment focus

Health Care, Software, Biotechnology
Seed, Funding Round, Series A
United States

Portfolio highlights

HighByte — HighByte is an industrial software development company in Portland, Maine building solutions that address the data architecture and security challenges created by Industry 4.0.
TOP the organic project — 100% Organic Cotton Period Care. Organic Tampons, Pads, First Period Kit & Bulk Period Products. Women-owned, eco-friendly, plant-based and sustainable. With every subscription, TOP gives back to women in need.
Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

Investment focus

Health Care, Biotechnology, Software
Seed, Series A, Funding Round
United States, Israel, Canada

Portfolio highlights

DeepLook Medical — Enhancing Medical Imaging with Revolutionary Software: DeepLook Medical envisions a future where data-driven imaging enables accurate, efficient, and personalized care across the entire treatment pathway.
Vytyl Health Management — Vytyl Health Management delivers quality mental health care to adolescents and transitional-age youth. The organization firmly believes that connection forms the basis for healing. They recognize the significant challenges ahead but remain steadfast in their conviction that through collaborative efforts, barriers can be overcome, meaningful bondscan be formed, and vital assistance can be extended to those in greatest need.
Nest Collaborative — Nest Collaborative offers online lactation consults. Virtual appointments are available same-day & are covered in full by most insurance plans.

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Investment focus

Health Care, Biotechnology, Pharmaceutical
Series B, Series C, Series A
United States, Germany, Switzerland

Portfolio highlights

Paperspace — Ceres, Inc. (Ceres) is an agricultural biotechnology company selling seeds to produce renewable biomass feedstocks. The Company’s large-scale commercial products are sweet sorghum varieties that can be used as a drop-in feedstock to extend the operating season of Brazilian sugarcane-to-ethanol mills. Its products include sweet sorghum, high biomasssorghum, switchgrass, miscanthus and row crops. Its energy crops can also be used for the production of second-generation biofuels and bio-based chemicals, including cellulosic ethanol, butanol, jet fuel, diesel-like molecules and gasoline-like molecules, from non-food biomass. Baseload utility scale electric power can also be generated from the biomass feedstocks grown from its seeds. Ceres has sold switchgrass and high biomass sorghum seeds in the United States under its Blade Energy Crops (Blade) brand. In January 2010, the Company incorporated a subsidiary, Ceres Sementes do Brasil Ltda.
CardioFocus — CardioFocus provides electrophysiologists with innovative and effective tools that bring precision and control to the treatment of atrial fibrillation.
Yolia Health — Yolia Health developed The True Vision Treatment or TVT, the 'Invisalign' for the eyes. A non-invasive treatment to correct vision problems like presbyopia without surgery. TVT is self-administered by the patient in his or her own home. It employs a combination of customized contact lenses (TVT Contacts) and specially formulatedeye drops (TVT Eye Drops). After only 5 days of treatment with TVT patients are able to stop using the TVT Contacts, TVT Eye Drops and their reading glasses for up to 12 months at a time before re-treatment with TVT is needed. What is even greater than correcting for presbyopia non-invasively, is correcting both eyes without compromising any distance vision. On the contrary, Yolia's treatment improves both near and distance vision, a unique feature no single other alternative can provide. ** Looking for sophisticated investors and key industry partners.

For over 20 years we have been a successful healthcare venture capital firm rooted in the Midwest. Check out our portfolio companies.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Series C
United States, Canada

Portfolio highlights

BrightSpec — LabBrightSpec addresses high-value, time-sensitive analytical chemistry challenges that are not well addressed by other spectroscopy techniques and instruments. It provides innovative laboratory services in order to deliver immediate results to potential customers of our instrumentation products. They are based in Charlottesville, Virginia,about two hours from Washington, DC. The BrightSpec Fourier transform molecular rotational resonance (FT-MRR) product platform is based on technology developed at the University of Virginia by Brooks Pate and his team, several of whom now work at BrightSpec. They offer FT-MRR product configurations for analytical chemistry and gas sensing in manufacturing process control, quality control, environmental monitoring, and formulation research.
Boomerang Medical — Boomerang Medical is a bioelectronic medicine company targeting autoimmune diseases.
Virtual Incision — Virtual Incision is reimagining robotic support for minimally invasive (MIS) procedures with simple innovations offering mobility, flexibility, and accessibility to provide MIS options to more patients. It has develops the MIRA® (Miniaturized In vivo Robotic Assistant) Platform, a first-of-its-kind miniaturized surgical robotic support device,focusing first on colon resection, with follow-on specialty robots for additional potential applications.

North Coast Ventures (formerly North Coast Angel Fund) is comprised of four contributed capital funds with a focus on early-stage technology investments. Our membership consists of a number of Ohio's leading investors, entrepreneurs, and business leaders who are dedicated to accelerating early-stage ventures.North Coast Ventures members playan active role by generating deal flow, serving on due diligence teams, working with portfolio companies, or serving on the Investment Screening and Executive Committees. Through this involvement, our goal is to provide a supportive environment for our portfolio companies and ultimately enhance the performance of our Fund.Northeast Ohio has a long tradition of active and successful angel investing, but until recently, the success of this crucial form of funding has hinged on the efforts of a relatively small number of individual investors. As the region’s first professionally managed angel fund, North Coast Angel Fund works to improve the early-stage funding environment for both entrepreneurs and investors.

Investment focus

Health Care, Software, Medical Device
Series A, Seed, Funding Round
United States

Portfolio highlights

Narratize — Our generative AI software helps innovative enterprises quickly produce impactful, accurate, compelling communications and deliverables by distilling their ideas and expertise.
UnifyWork — UnifyWork's skills-based matching technology creates a faster way for employers to hire qualified talent, and helps job seekers find job opportunities meeting their skills and interests.
Society Brands — Society Brands is building a community of entrepreneurs and Amazon brands that can help one another reach new heights. That means we acquire small and medium-sized ecommerce businesses to build a house of brands where entrepreneurs flourish and explore their true potential.

We’re (not just) investors.We’re (more than) advisors.We’re (beyond) connectors.Ben Franklin Technology Partners combines the best practices of early stage investing with a higher purpose – to lead the region’s technology community to new heights, creating jobs and transforming lives. For over 30 years, Ben has been the leading seedstage capital provider for the region’s technology sectors, investing over $170 million in more than 1,750 regional technology companies, many of which have gone on to become industry leaders. Ben Franklin has also launched university/industry partnerships that accelerate scientific discoveries to commercialization, and has seeded regional initiatives that strengthen our entrepreneurial community.

Investment focus

Health Care, Software, Information Technology
Seed, Grant, Debt Financing
United States

Portfolio highlights

SkillCycle — Develop your talent with GoCoach's personalized, online coaching platform. Increase your team's productivity with our top professional coaches.
SFA Therapeutics — SFA Therapeutics is a development-stage bio-pharmaceutical startup company focused on a new advancement in the treatment of chronic inflammatory disease - the use of microbiome-derived metabolites as drugs.
Avisi Technologies — Avisi Technologies is developing a nanotechnology-enabled defense against blindness from glaucoma.

U.S. Venture Partners (USVP) is a venture capital partnership, helping entrepreneurs transform their ideas and efforts into world-changing companies. The firm focuses on early-stage ventures in information technology and health care, where innovation is unbridled and has led to the creation of economic wealth and millions of jobs over the pastthirty-plus years of the firm's existence. Areas of particular interest to our investment professionals include enterprise software, IT security, consumer internet, mobile, and e-commerce, healthcare, and IT-enabled healthcare services. The USVP team consists of former entrepreneurs, technologists, corporate executives, financial professionals, and industry domain experts.

Investment focus

Software, Health Care, Information Technology
Series B, Series C, Series A
United States, Israel, Canada

Portfolio highlights

IONIX — IONIX helps you secure your organization with our cutting-edge attack surface management solutions. Protect your digital assets and minimize risk exposure today.
Zero Networks — We make microsegmentation the easiest & most effective way to protect your company. Enable MFA network solution anywhere to block ransomware & advanced attacks.
Cagent Vascular — Cagent Vascular Inc. is a developer of next generation angioplasty balloons using Serration Technology for the treatment of cardiovascular disease.

Horizon is a venture lending platform that offers structured debt products to life science and technology companies. Its team of investment and operations professionals has been providing debt capital to some of the most exciting companies for decades. The members of the Horizon team have, collectively, originated and invested more than $5 billionin venture loans to thousands of companies.The company was founded in 2003 and is headquartered in Farmington, Connecticut.

Investment focus

Health Care, Biotechnology, Medical Device
Debt Financing, Post-IPO Debt, Funding Round
United States, Canada, India

Portfolio highlights

Unagi Scooters — Unagi is an electric scooter startup that aims to liberate people from the tyranny of transportation frustrations—the costs, inconveniences, the carbon emissions. So we built the ideal personal liberation device.
Evelo Biosciences — Evelo Biosciences is dedicated to improving the lives of patients globally through the development of a new modality of medicines – monoclonal microbials. Monoclonal microbials are orally delivered medicines that modulate systemic immunology and biology through direct interactions with human cells in the gut. These new medicines are broadlyapplicable across many diseases – including autoimmune, immunoinflammatory, metabolic, neurological, neuroinflammatory diseases and cancer. Monoclonal microbials have the potential to fundamentally change traditional models of drug discovery and development. By finding and selecting naturally occurring monoclonal microbials with defined therapeutic effects, Evelo can improve the speed, cost and success of drug discovery and development. Evelo’s platform enables pharmacological intervention at all stages of disease with naturally occurring, safe and effective monoclonal microbials. Evelo Biosciences was conceived and created within VentureLabs®, Flagship Pioneering’s institutional innovation foundry, and launched by Flagship in 2015.
Viken Detection — Viken Detection is a research and technology development company focusing on X-ray physics and the design of analytical devices. The company's devices provide security imaging and material identification, which help to protect the public from terrorism and other dangerous dangers, allowing law enforcement and safety inspection agencies toremain vigilant and avoid drug trafficking.Viken was founded in 2013 and is headquartered in Newton, Massachusetts, United States.

Khosla Ventures invests in companies that are bold, early and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs. Headquartered in Menlo Park, Calif., Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech,digital health, medtech and diagnostics, therapeutics and frontier technology.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Metaplane — Metaplane is a data observability platform that helps data teams know when things break, what went wrong, and how to fix it.
Loyal — Loyal is a biotechnology company developing medicines to extend dog lifespan. By developing drugs with the potential to slow the aging process, they aim to delay or prevent age-related diseases like cancer and dementia.
Varda — Expanding the economic bounds of humankind with the world's first orbital manufacturing & reentry platform.

For over two decades, Sand Hill Angels has worked openly and collaboratively with venture capital funds, other angel organizations, and the Bay Area ecosystem that fosters the growth of technology startups.

Investment focus

Health Care, Software, Biotechnology
Seed, Series B, Series A
United States, Canada, Japan

Portfolio highlights

Pulzaid — Platform for hybrid specialty care
GaeaStar — The zero waste clay cup. GaeaStar is an engineering company developing sustainable multiple use products and technology.
PrivacyHawk — PrivacyHawk is a Personal Data Protection service that makes opting out, unsubscribing, and deleting your data from thousands of companies easy.

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

Investment focus

Software, Biotechnology, Health Care
Series A, Series B, Series C
United States, Israel, India

Portfolio highlights

Anzenna — 74% of security breaches are due to human error. Anzenna is a User Security Posture Management (USPM) platform that helps companies deter, detect and disrupt insider risk.
Acesion Pharma — Acesion Pharma ApS is a Danish biotech company founded in 2011 and based in Copenhagen. Acesion Pharma develops more efficacious and safe drugs for the treatment of atrial fibrillation (AF), the most common type of cardiac arrhythmia.
AgomAb Therapeutics — AgomAb is developing molecular therapies for the regeneration of damaged tissues. Their unique agonistic monoclonal antibody molecules (“agomAbs”) stimulate molecular and cellular repair mechanisms that have the potential to restore organ function in patients with fibrotic, inflammatory, autoimmune and degenerative diseases.

Delphi Ventures leverages years of experience, passion, & expertise to advance new technologies and build market leading biotechnology companies.

Investment focus

Health Care, Biotechnology, Medical Device
Series C, Series B, Series D
United States, Canada, Denmark

Portfolio highlights

Anoma — A sovereign, proof-of-stake blockchain protocol that enables private, asset-agnostic cash and private bartering among any number of parties.
HYTOPIA — HYTOPIA is a metaverse platform that integrates social functions and offers developers a Minecraft-inspired game creation toolkit with flexible monetization.
Pixelmon — Collect, Evolve & Battle alongside your Pixelmon in our Multiplayer Open World Adventure and Monster Combat Arena.

Catalyst Health Ventures is an early-stage venture capital firm targeting technology solutions applied within the health care and life science industries. At the core of this strategy is a committed, hands-on approach to working with management and syndicate partners to build successful companies. Their disciplined investment process leverages bothintellectual and financial capital to originate deals, cultivate opportunities, and realize the full potential of emerging ventures in the health care and life science marketplace. We seek to invest in companies addressing major global unmet clinical needs in areas such as oncology, cardiovascular disease, obesity, and women’s health. We invest in pioneering and proprietary technological solutions fundamentally designed to reduce treatment costs and improve patient outcomes. By investing in solutions which have a technological foundation of engineering and development such as medical devices, diagnostic tools and instrumentation and consumer healthcare, we minimize the risks related to uncertain scientific experimentation.

Investment focus

Health Care, Medical Device, Medical
Series A, Series B, Series C
United States

Portfolio highlights

Epitel — Epilog is an unobtrusive wearable seizure detection system that records long-term EEG, anywhere. It gives people living with epilepsy peace of mind with a much-needed tool to better understand and manage their seizures.
Avive Solutions — Check out Avive Solutions, the manufacturers of a brand new AED machine - portable defibrillator - that's FDA approved!
PanTher Therapeutics — PanTher Therapeutics is on a mission to revolutionize cancer care with a proprietary treatment platform designed to enhance therapeutic response with minimal side effects. PanTher’s highly adaptable platform empowers oncologists to treat patients with life-threatening cancer by unlocking a drug’s full potential through direct, sustained treatmentat the tumor site. This distinctive targeting capability uniquely positions PanTher to take on the deadliest and most difficult to treat cancers with a lead investigational candidate in pancreatic cancer.

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Switzerland, Canada

Portfolio highlights

Nouscom — Nouscom is a next-generation immunotherapy company developing genetic cancer vaccines and oncolytic viruses..
Firefly Bio — Firefly specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders.
Tentarix Biotherapeutics — Enabling intelligent therapies with multifunctional biologics.

Catalyst Health Ventures is an early-stage venture capital firm targeting technology solutions applied within the health care and life science industries. At the core of this strategy is a committed, hands-on approach to working with management and syndicate partners to build successful companies. Their disciplined investment process leverages bothintellectual and financial capital to originate deals, cultivate opportunities, and realize the full potential of emerging ventures in the health care and life science marketplace. We seek to invest in companies addressing major global unmet clinical needs in areas such as oncology, cardiovascular disease, obesity, and women’s health. We invest in pioneering and proprietary technological solutions fundamentally designed to reduce treatment costs and improve patient outcomes. By investing in solutions which have a technological foundation of engineering and development such as medical devices, diagnostic tools and instrumentation and consumer healthcare, we minimize the risks related to uncertain scientific experimentation.

Investment focus

Health Care, Medical Device, Medical
Series B, Series A, Series C
United States

Portfolio highlights

Rejoni — Learn about a clinical trial that is evaluating a new product which may prevent them.
Instylla — Instylla delivers next-generation liquid embolics for interventional radiology, with initial clinical applications in interventional oncology and peripheral hemostasis.
Avive Solutions — Check out Avive Solutions, the manufacturers of a brand new AED machine - portable defibrillator - that's FDA approved!

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Seed, Series A
United States, Canada, United Kingdom

Portfolio highlights

Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
BeeReaders — ## Build Setup
Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.

Kleiner Perkins is an American venture capital firm headquartered on Sand Hill Road in Menlo Park in Silicon Valley.

Investment focus

Software, Health Care, Information Technology
Series B, Series A, Series C
United States, China, United Kingdom

Portfolio highlights

Inkitt — Publish stories online, join our author subscription program, and read books online for free. Join the Inkitt community for writers and readers today.
Youpinmei — Youpenmei is a company that create an intelligent, two-way, integrated "new" comprehensive e-commerce platform for offline community stores and distributors.
Together AI — Together will enable researchers, developers & companies to leverage and improve artificial intelligence with an intuitive data, models & computation platform.

Gaingels is a leading venture investment syndicate in support of diversity, inclusive of the LGBTQIA+ community and allies in the venture capital space.

Investment focus

Software, Health Care, FinTech
Seed, Series A, Series B
United States, Canada, Mexico

Portfolio highlights

ValidMind — ValidMind is the most efficient solution for governance & risk management of AI and LLMs. Automate model documentation and validation for all model types.
Summer — Summer partners with employers help their populations navigate and reduce student loan debt. Summer is a certified B-Corp.
Mermaid Chart — Building the next generation of smart diagramming for enterprise teams. Easily create and collaborate on complex diagrams from text.

Tech Coast Angels is the largest angel investor group in the United States, possessing more than 300 members in five networks in Los Angeles, Orange County, San Diego, Central Coast, and the Inland Empire. Its members provide funding and guidance to more early-stage, high-growth companies in Southern California than any other investment group.Members invest in companies in a wide range of industries, including the life sciences, biotech, IT, services, retail, Internet, financial, software, media, consumer products, and tech startups. TCA as a whole gives companies more than just capital; they also provide counsel, mentoring, and access to an extensive network of potential investors, customers, strategic partners, and management talent. Tech Coast Angels has been ranked by CB Insights to be among the Top 20 Angel Groups in the US; TCA was also ranked as #1 for Network Centrality, meaning we have more connections than anyone! If you are in the game-changing business, we are here to help.

Investment focus

Software, Health Care, Biotechnology
Seed, Convertible Note, Funding Round
United States, Canada

Portfolio highlights

Reglagene — Reglagene is a therapeutics company that leverages its expertise in the design and development of brain penetrant medicines to create breakthrough therapies for the safe and effective treatment of brain diseases.
RealSeq Biosciences — RealSeq Biosciences’ core expertise includes innovative proprietary technologies for bias-free small RNA/miRNA NGS library construction.
Trio Pharmaceuticals — Trio Pharmaceuticals is a cancer therapeutics company that develops dual-action drugs for immunogenic tumors. These drugs directly stop tumor growth and selectively stop immunosuppression in the tumor without targeting the current immune checkpoint pathways. The company was founded in 2018 and is headquartered in San Diego, California.

Split Rock Partners invests in emerging healthcare, software and Internet services companies in the Upper Midwest and West Coast. They are an early-stage venture capital firm that was founded in June 2004 by the former healthcare and software investment teams of St. Paul Venture Capital (SPVC). The Split Rock team managed over $1 billion of venturecapital during our tenure at SPVC, and continues to manage the SPVC healthcare and software portfolio. In May of 2008, they raised $300 million in the second Split Rock Partners fund, the successor to their inaugural $275 million fund raised in April 2005.The Split Rock team believes that it takes great people to translate promising ideas into compelling businesses. They are grounded in a fundamental respect for entrepreneurs and the rare combination of elements required when pioneering new markets. They start by looking for entrepreneurs with the passion, vision, and skills to build leading companies. They then work with entrepreneurs collaboratively, building partnerships based on integrity and mutual respect. The Split Rock team complements management expertise with over 80 years of venture investing and entrepreneurial management experience. They are proud of the strong relationships they have built with talented entrepreneurs and co-investors throughout their history and look forward to building on that tradition.

Investment focus

Health Care, Medical Device, Medical
Series A, Series B, Series C
United States, France

Portfolio highlights

Gravia — More benefits. Fewer asterisks. We are a health benefits company on a mission to build a health plan that everyone can love.
EBR Systems — EBR Systems, Inc. is an early-stage development venture pursuing novel approaches in cardiac rhythm management. EBR Systems develops devices for the treatment of cardiac arrhythmias.
Gravie — More benefits. Fewer asterisks. We are a health benefits company on a mission to build a health plan that everyone can love.

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

Investment focus

Health Care, Software, Information Technology
Seed, Funding Round, Series A
United States, Canada, United Kingdom

Portfolio highlights

CaseCTRL — Schedule surgeries with ease using AI-powered surgical scheduling. Fewer canceled cases, conflicts, and misorders. More surgery and time for patients!
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
Amplified Sciences — Amplified Sciences is a molecular diagnostics company unlike other diagnostics companies due to their ultra-sensitive molecular sensing technology with composition of matter IP exclusively licensed from Purdue University. The technology is disease state agnostic, can detect to the single molecule level, scales easily to point of care, and providesa very favorable cost structure for their platform of reagents. The first application – early detection of pancreatic cancer - is an assay that will quickly prove the investment thesis due to large unmet medical need and a favorable reimbursement path. The team has delivered a working prototype and published proof of concept data.

Third Rock Ventures is a leading healthcare venture firm focused on advancing disruptive areas of science and medicine to deliver breakthroughs to patients.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States

Portfolio highlights

Flare Therapeutics — Flare Therapeutics is a biotechnology company opening up a new therapeutic space with a novel approach to decipher the biology of transcription factors to develop small molecule medicines. Based on insights from the seminal work of its scientific founders, Flare’s team has uncovered ‘switch sites,’ druggable regions that are key targets fortranscription factor regulation to address mutations that cause disease. Our drug discovery to target switch sites has rapidly advanced, resulting in an emerging pipeline of drug programs that address well-validated transcription factors, initially focused on precision oncology with future potential in neurology, rare genetic disorders, immunology, and inflammation.
Rapport Therapeutics — Precision medicines to match the complexity of the human brain.
Synnovation Therapeutics — Synnovation Therapeutics is a precision oncology company focused on small molecule therapies optimized to target key driver mechanisms in cancers. It is dedicated to the discovery and development of therapeutics that can improve the lives of people with cancer. Leveraging its deep expertise in medicinal chemistry, cancer biology, andpatient-focused precision medicine, it builds a diverse pipeline of novel small-molecule targeted therapies. It aims to efficiently advance these agents into clinical trials with the goal of transforming cancer patient care.

DeNovo Ventures was formed in 2000 by seasoned investors and experienced medical device entrepreneurs who sought to share the lessons learned from a history of successful investing and building successful companies. They believed that their unique combination of skills and perspectives could help entrepreneurs to build companies which would havesignificant clinical impact and generate superior returns. Seven years later, this belief continues to hold true, demonstrated by investment success in selected medical device and biotechnology companies. With $650 million under management, De Novo has made more than 40 investments in medical devices and biotechnology across three funds. They invest in all stages of enterprise development and growth â€“ from early stage to late stage. The unique background of leading companies as entrepreneurs and operating executives from start to exit enables us to advise entrepreneurs and management teams over the full life cycle of the company.

Investment focus

Health Care, Medical Device, Biotechnology
Series B, Series D, Series C
United States

Portfolio highlights

Avedro — Glaukos works relentlessly to create and deliver transformative therapies for patients struggling with glaucoma, corneal disorders, and retinal diseases.
Milo — Milo is a group action communicator, sophisticated wireless networking, audio processing & powerful hardware in a carefully crafted design.
Spinal Kinetics — The artificial disc replacement device from Orthofix is changing the lives of people suffering from spinal pain. Learn about this motion-saving product.

Life Science Angels, Inc. (LSA) is the premier angel investment group focused solely on healthcare investing, including medical devices, diagnostics, pharmaceuticals, biotechnology, and digital health.

Investment focus

Biotechnology, Health Care, Medical
Funding Round, Seed, Series A
United States, Israel, The Netherlands

Portfolio highlights

InnoSIGN — We are passionate to bring to market our OncoSIGNal pathway activity profiling technology contributing to a better understanding of disease mechanisms in oncology. OncoSIGNal enables next generation precision medicine by translating molecular data into functional cell behavior.
Allyx Therapeutics — Allyx Therapeutics is a clinical-stage biotechnology company that develops therapies designed to reverse neurodegeneration. Allyx Therapeutics' product is an orally bioavailable small molecule that acts as a silent allosteric modulator, enabling clinicians to get a drug that is capable of delivering a disease-modifying approach and preservecognition in patients.
Avisi Technologies — Avisi Technologies is developing a nanotechnology-enabled defense against blindness from glaucoma.

ShangBay Capital is a venture capital company that brings best-in-class investments mainly in the U.S. medical devices technology, as well as biotech, and mobile healthcare sectors through early-stage venture equity participation

Investment focus

Health Care, Medical Device, Biotechnology
Series A, Series B, Series D
United States, China, Canada

Portfolio highlights

Luminopia — Luminopia is the first FDA-approved binocular therapy for amblyopia.
Presidio Medical — Building Tomorrow's Neuromodulation Therapies. Presidio Medical is a clinical-stage, privately held medical technology company developing a transformational neuromodulation platform to treat diseases of undesired neural activity.
Laplace Interventional — Laplace developing Transcatheter Tricuspid Valve Technology to offer an increase in life expectancy and an improvement to the quality of life to worldwide patients with tricuspid regurgitation.

The St. Louis Arch Angels is a network of accredited investors who fund early-stage businesses across the St. Louis region.

Investment focus

Biotechnology, Health Care, Software
Seed, Series A, Funding Round
United States, Argentina

Portfolio highlights

Peptyde Bio — Peptyde Bio is an Agtech startup positioned to become the go-to supplier of new AMPs.
SentiAR — SentiAR is digital health, software device company adding a new dimension to clinical practice in interventional procedures. Spun out of Washington University, we are developing the first 3D visualization platform using real-time holography of the patient's anatomy and catheter location, "floating" over the patients, with a goal toprovide the clinician and patient a faster, safer delivery of care.SentiAR’s mission is to transform the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.The visualization is fully controllable “hands-free” by the clinician, providing an ergonomic breakthrough for the treatment and analysis of cardiac arrhythmias within an interventional catheter lab environment. SentiAR is developing the platform for eventual FDA submission.
Impetus Agriculture — Impetus Agriculture focuses on developing multiple topical or transgenic insect control products. Products that are safe, effective, and sustainable. Products that are not subject to the same insect resistance that has developed in current commercial products.

Silicon Valley Bank is the financial partner of the innovation economy; helping individuals and investors in the innovation ecosystem achieve extraordinary outcomes.

Investment focus

Software, Health Care, Biotechnology
Debt Financing, Series B, Series A
United States, United Kingdom, Canada

Portfolio highlights

Carputty — Carputty is a superior way to finance a car. Buying new, used, or refinancing? Carputty's flexible line of credit simplifies the process. Get started now!
Coast — Coast is the simple, all-in-one fleet and fuel card that helps businesses easily pay for and track vehicle expenses. It's quick to set up, easy-to-use, and full of rewards.
HawkEye 360 — HawkEye 360 is a space-based RF data analytics company with one-of-a-kind solutions to better spectrum mapping and monitoring on land & water

Green Park & Golf, built on over 50 years of operational and financial experience, seeks investment opportunities that offer above-market returns for its investors. Led by Clay Heighten, M.D., and Carl Soderstrom, the Firm delivers strategic solutions, financial backing and a reliable network to its portfolio companies. The Dallas-based Firm iscurrently looking for investment opportunities in medical-related start-ups.Dr. Heighten founded MedicalEdge Healthcare Group in 1993, and Mr. Soderstrom started PhyServe Physician Services in 1998 to administer the financial and operational needs of MedicalEdge. Together, the companies managed over 550 providers in five major markets. In 2011, the companies were sold to Texas Health Resources, a $3.8 billion health care system. That’s when Green Park & Golf was born.After earning his MBA at Southern Methodist University, Mr. Garcia joined them full-time in May 2011 to actively pursue new investment opportunities and monitor other investments in their portfolio. He has prior professional experience at FedEx, Bold Ventures, and Lone Star Investment Advisors.

Investment focus

Health Care, Medical, Biotechnology
Series A, Seed, Series B
United States, Israel, Sweden

Portfolio highlights

Validic — Meet the only EHR-integrated remote care solution delivering personalized care for clinicians and patients, making personal health data actionable.
Prolocor — Our goal is to develop a more precise method and diagnostic tool for assessing and managing risk in cardiovascular disease.
Worlds — Worlds is completely re-inventing how organizations see and understand their worlds. Through live, AI-powered models, the company’s clients can remotely see, learn and analyze their worlds in ways that were never possible before.

Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!

Investment focus

Software, Health Care, Information Technology
Seed, Series A, Funding Round
United States, Germany

Portfolio highlights

Lentechs — CREATING A NEW VISION LENTECHS is a privately-held, clinical-stage, ophthalmic medical device company in Columbus, Ohio dedicated to improving vision at every stage of life through innovative design and breakthrough contact lens technology. LENTECHS is focused on developing a patented, first-of-its-kind line of soft, suspended contact lens designed to deliver exceptional, glasses-like vision at all
Basking Biosciences — Basking Biosciences is a startup that’s developing a therapy to restore blood flow to the brain during ischemic stroke, preventing hemorrhage and long-term damage.
Clarametyx Biosciences — Clarametyx Biosciences is a late preclinical stage biotechnology company developing targeted, immune-enabling biologic therapies to counter persistent infections associated with biofilms.

Morgenthaler Ventures has been in the venture capital business for more than 45 years, steadily investing through every market cycle. Select past and present portfolio companies in the IT space include: Evernote, Lending Club, Siri, MuleSoft, Practice Fusion, Adara Media, Check, Doximity, PeopleMatter, Socrata, NuoDB, Jaspersoft, VoltageSecurity, Rhythm NewMedia, Nominum, Wize Commerce (NexTag) and back in the day, Apple.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Series C
United States, Canada, France

Portfolio highlights

Moximed — Moximed Inc. is dedicated to improving the standard of care for patients with osteoarthritis, and is investigating therapies to treat a number of affected joints. The lead product, the KineSpring® Knee Implant System, is designed for patients with knee osteoarthritis.
SetPoint Medical — SetPoint Medical is pioneering bioelectronic medicine to develop a safe and cost-effective approach for treatment of chronic autoimmune diseases.
Relievant Medsystems — Relievant's mission is to provide patients with low risk therapy that can alleviate their back pain.

Three Arch Partners was formed in 1993 to provide young companies with access to relevant clinical and business resources, as well as capital. Three Arch has helped create, build and fund more than 100 important new healthcare companies. These companies have often become the clinical and market leaders in their respective fields, and have generatedstrong returns. The fund focuses on opportunities in medical devices and healthcare services, and less frequently in biotechnology.

Investment focus

Health Care, Biotechnology, Medical Device
Series B, Series C, Funding Round
United States, Belgium

Portfolio highlights

Nevro — We Believe True Innovation Transforms More Lives
Neuronetics — Antidepressant medications don't work for everyone. If drugs haven't worked for you, learn about NeuroStar - safe, effective, lasting TMS therapy for depression.
Access Closure — Access Closure, Inc., a medical device company, provides access site management products to address the complex challenge of vascular closure during interventional and diagnostic procedures. The company's products include Mynx delivery system, a vascular closure device that seals the arteriotomy using a water-soluble and extravascular sealant,which expands in the tissue tract by absorbing blood and subcutaneous fluids. Access Closure, Inc. was founded in 2002 and is based in Mountain View, California.

Virginia Venture Partners is a family of seed-stage investment funds placing near-equity and equity investments in Virginia-based technology, life science, and cleantech companies. Virginia Venture Partners invests in companies with a high potential for achieving rapid growth and generating significant economic returns for entrepreneurs,co-investors, and the Commonwealth of Virginia. CIT’s family of funds includes:GAP Fund I is a vintage 2004 fund fully invested in a broad array of seed-stage technology companies. Portfolio.GAP BioLife Fund is a seed fund investing exclusively in life science companies.GAP Tech Fund is a seed fund investing in IT and technology companies.

Investment focus

Software, Health Care, SaaS
Seed, Funding Round, Series A
United States, Canada, France

Portfolio highlights

CarpeDM — CarpeDM app is an exclusive member-only dating community created for singles seeking meaningful relationships with professional Black women.
WRANGLD — WRANGLD operates as a SaaS company that provides a platform for the trades and service industries.
OpsCanvas — Your ultimate solution for effortless cloud deployments, with an intuitive visual interface designed specifically for developers.

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Funding Round
United States, Canada

Portfolio highlights

Cardiosense — Cardiosense offers a physiological waveform AI platform to develop predictive biomarkers for the detection and treatment of disease. Its platform leverages multi-modal sensors and industry-leading AI to develop predictive biomarkers for the detection and treatment of disease.
Aer Therapeutics — Aer Therapeutics is a clinical stage biopharmaceutical company developing a novel inhaled approach to treat lung disease with excess mucus and mucus plugs.
Mercy BioAnalytics — We are making early stage cancer 100,000x easier to find using extracellular vesicles found in blood, specific to their parent cells.

Privately Held Companies

Investment focus

Health Care, Biotechnology, Medical
Series A, Series B, Series C
United States, Canada, New Zealand

Portfolio highlights

BeeKeeperAI — BeeKeeperAI is a zero trust collaboration platform protecting both algorithm IP and regulated data.
Solu Therapeutics — Solu Therapeutics is a precision-medicine-focused company developing therapeutics to eliminate disease-driving cells.
Surgical Safety Technologies — Making Surgery Safer. Unifying safety, efficiency and compliance in healthcare with over a decade of research and clinical experience.

Mayo Clinic, a not-for-profit medical group practice, provides medical care, research, and education services. It offers medical care services in various specialties, including diabetes and endocrinology, gastroenterology, gynecology, cancer, neurology and neurosurgery, orthopedics, pulmonology, rheumatology, nephrology, urology, and cardiology andheart surgery.

Investment focus

Health Care, Biotechnology, Medical
Series A, Series B, Seed
United States, Israel, China

Portfolio highlights

InfoBionic — InfoBionic transforms the efficiency and the economics of ambulatory remote patient monitoring processes and cardiac diagnostic services by optimizing clinical and real-world utility for the users that need it most – physicians and their patients. It has developed the MoMe System, a remote patient monitoring platform initially focused on cardiacarrhythmia detection, to improve clinical efficiency and patient care with any time, anywhere access to patient data. The company was founded in 2011 and is headquartered in Waltham, Massachusetts.
UpDoc — UpDoc is a technology-enabled services firm that offers the world's first unique conversational AI platform for autonomous prescription management.
vMocion — vMocion, LLC is a Media and Entertainment company that holds the exclusive, global, perpetual license for Mayo Clinic’s Galvanic Vestibular Stimulation (GVS) patents and algorithms within all media and entertainment categories. The company was formed by Hillstrom Media Technology, LLC (HMT) and Mayo Clinic to create vMocion’s 3v™ Platform, whichcan be licensed and integrated into a variety of media and entertainment applications, including virtual reality (VR) and augmented reality (AR) platforms.

Keiretsu Capital LLC is an affiliate of the World's Leading Angel Network, Keiretsu Forum, and manages funds which enable limited partners to co-invest in the proprietary deal flow of the angel investors.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Series A, Seed
United States, Canada, India

Portfolio highlights

Clensta — Clensta is a biotechnology start-up to improve the National Hygiene condition whilst addressing the aspect of water conservation. Clensta is an Indian startup and in association with IIT Delhi, works to create innovative healthcare solutions to make hygiene accessible for anyone, anytime, and anywhere. Driven by their aim to create products thatpromote complete cleaning solutions without water.
EarthGrid PBC — EarthGrid seeks to revolutionize US outdated infrastructure with innovative tunneling and trenching solutions, through the power of plasma.
Another Tomorrow — Conscious Clothing. Education. Action. Another Tomorrow pushes the boundaries of what responsibly grown, and ethically manufactured materials can achieve. Sensual and strong, our collection is designed for living.

Cherrystone Angel Group, founded in 2004 and comprised of over 60 Rhode Island members, is Rhode Island’s first organized angel investment group. Its members invest in early stage, typically pre-revenue companies, across the tri-state region. While it is the entrepreneur who drives the company — and on whom ultimate success depends —Cherrystone believes that good advice and focused expertise are vital to the success of any business venture. When Cherrystone invests, it not only brings money to the table but industry knowledge and connections that will make its business succeed. All its members are experienced and qualified investors who have either built their own companies or have extensive experience launching new business ventures. Their backgrounds include creating or working with manufacturing, distribution, technology, and service companies.

Investment focus

Biotechnology, Health Care, Medical Device
Series A, Series B, Seed
United States

Portfolio highlights

Jaia Robotics — Aquatic data collection is our passion using micro sized low cost hybrid autonomous surface vehicles and underwater vehicles.
Lenoss Medical — Lenoss Medical engages in providing solutions that support the natural osseous healing process. They disrupt the treatment of spinal fractures with the osteopearl VBA system, a viable, minimally invasive, and cement-free technology that utilizes the natural healing properties of healthy bone.
Advanced Silicon Group — Advanced Silicon Group operates a nanotechnology company dedicated to commercializing silicon nanotechnology. The company was founded in 2015 with the goal of commercializing silicon nanotechnology developed by ASG employees.