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Top 50 Life Science VC Funds & Investors in United States (August 2026)

The most active venture capital funds investing in United States Life Science startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in United States Life Science startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
ARCH Venture Partners
VC Fund
40 United States, China, United Kingdom Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $10M–$250M
Alexandria Venture Investments
VC Fund
29 United States, Canada, France Series A, Series B, Seed Biotechnology, Health Care, Therapeutics $2M–$150M
Alumni Ventures
VC Fund
23 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1.5M–$79M
Third Rock Ventures
VC Fund
22 United States Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $11M–$190M
SOSV
VC Fund
21 United States, India, United Kingdom Seed, Convertible Note, Pre-Seed Biotechnology, Health Care, Software
Northpond Ventures
VC Fund
21 United States, United Kingdom, Canada Series A, Series B, Series C Biotechnology, Health Care, Life Science $10M–$95M
Atlas Venture
VC Fund
21 United States, United Kingdom, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $3.5M–$115M
OrbiMed
VC Fund
19 United States, China, Israel Series B, Series A, Series C Biotechnology, Health Care, Medical $10M–$183M
Gaingels
VC Fund
18 United States, Canada, Mexico Seed, Series A, Series B Software, Health Care, Artificial Intelligence $1M–$100M
RA Capital Management
VC Fund
18 United States, United Kingdom, Canada Series B, Series C, Post-IPO Equity Biotechnology, Health Care, Therapeutics $27M–$240M
8VC
VC Fund
17 United States, United Kingdom, Canada Series A, Seed, Series B Software, Health Care, Artificial Intelligence $2.5M–$175M
Google Ventures
VC Fund
17 United States, United Kingdom, Israel Series A, Series B, Seed Software, Health Care, Biotechnology $1.1M–$125M
Andreessen Horowitz
VC Fund
15 United States, United Kingdom, Brazil Series A, Seed, Series B Software, Information Technology, Artificial Intelligence $1.7M–$112M
Flagship Pioneering
VC Fund
14 United States, Canada, United Kingdom Series B, Series C, Series A Biotechnology, Health Care, Medical $6.5M–$230M
Novartis Venture Fund
VC Fund
14 United States, Switzerland, United Kingdom Series B, Series A, Series C Biotechnology, Health Care, Therapeutics $5.1M–$120M
DCVC
VC Fund
14 United States, Canada, United Kingdom Seed, Series A, Series B Software, Artificial Intelligence, Machine Learning $1.5M–$139M
The Column Group
VC Fund
13 United States Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $15M–$120M
Alix Ventures
VC Fund
13 United States Seed, Series A, Pre-Seed Health Care, Biotechnology, Life Science $2M–$70M
KdT Ventures
VC Fund
13 United States, India, Canada Seed, Series A, Series B Biotechnology, Health Care, Medical $2.6M–$175M
Fifty Years
VC Fund
12 United States, Germany, Canada Seed, Series A, Series B Biotechnology, Health Care, Artificial Intelligence $2M–$91M
Felicis
VC Fund
12 United States, Canada, Germany Series A, Seed, Series B Software, Artificial Intelligence, SaaS $1.5M–$76M
Apple Tree Partners
VC Fund
12 United States, Canada, United Kingdom Series A, Series B, Seed Biotechnology, Health Care, Therapeutics $3.5M–$100M
General Catalyst
VC Fund
12 United States, United Kingdom, India Series A, Seed, Series B Software, Artificial Intelligence, Health Care $2M–$130M
Lux Capital
VC Fund
12 United States, United Kingdom, Canada Series A, Seed, Series B Software, Artificial Intelligence, Health Care $1.8M–$150M
Civilization Ventures
VC Fund
12 United States, United Kingdom, Brazil Seed, Series A, Series B Biotechnology, Health Care, Medical $1.8M–$144M
Sahsen Ventures
VC Fund
11 United States, China, Ghana Seed, Series A Biotechnology, Health Care, Non Profit $1.2M–$81M
Omega Funds
VC Fund
11 United States, Switzerland, United Kingdom Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $14M–$208M
Catalio Capital Management
VC Fund
11 United States, Switzerland, Israel Series A, Series B Biotechnology, Health Care, Life Science $15M–$150M
Liquid 2 Ventures
VC Fund
11 United States, Mexico, Canada Seed, Series A, Pre-Seed Software, Artificial Intelligence, Information Technology $125k–$50M
Artis Ventures
VC Fund
11 United States, United Kingdom, India Series A, Series B, Seed Health Care, Biotechnology, Software $2M–$127M
MPM Capital
VC Fund
11 United States, Canada, United Kingdom Series B, Series A, Series C Biotechnology, Health Care, Pharmaceutical $10M–$116M
Cormorant Asset Management
VC Fund
11 United States, China, Switzerland Series B, Series C, Series A Biotechnology, Health Care, Medical $16M–$150M
F-Prime
VC Fund
11 United States, United Kingdom, China Series A, Series B, Series C Health Care, Biotechnology, Medical $9.2M–$150M
Digitalis Ventures
VC Fund
11 United States, United Kingdom, China Series A, Series B, Seed Biotechnology, Health Care, Medical $1.5M–$132M
Foresite Capital
VC Fund
11 United States, United Kingdom, China Series B, Series C, Series A Biotechnology, Health Care, Therapeutics $22M–$270M
Hatteras Venture Partners
VC Fund
11 United States, Canada Series A, Series B, Series C Health Care, Biotechnology, Medical $5M–$90M
SR One
VC Fund
10 United States, United Kingdom, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $3.7M–$175M
Longwood Fund
VC Fund
10 United States, United Kingdom, Italy Series A, Series B, Series C Biotechnology, Therapeutics, Health Care $16M–$152M
Connecticut Innovations
VC Fund
10 United States, Israel, Canada Seed, Series A Health Care, Biotechnology, Software $300k–$25M
TBD Angels
VC Fund
10 United States, Kenya, Hong Kong Seed, Pre-Seed, Angel Software, Artificial Intelligence, Health Care $54k–$16M
Pear VC
VC Fund
10 United States, Brazil, Spain Seed, Pre-Seed, Series A Software, Artificial Intelligence, Information Technology $500k–$40M
Biotechnology Value Fund
VC Fund
10 United States, Switzerland, Canada Post-IPO Equity, Series B, Series A Biotechnology, Health Care, Therapeutics $8.9M–$200M
Two Sigma Ventures
VC Fund
10 United States, Canada, Mexico Series A, Series B, Seed Software, Artificial Intelligence, Machine Learning $2.2M–$120M
Khosla Ventures
VC Fund
9 United States, India, United Kingdom Series A, Series B, Seed Software, Artificial Intelligence, Health Care $2M–$100M
Horizons Ventures
VC Fund
9 United States, United Kingdom, Canada Series A, Series B, Seed Biotechnology, Software, Artificial Intelligence $1M–$110M
Playground Global
VC Fund
9 United States, Canada, Italy Series A, Series B, Seed Software, Robotics, Biotechnology $2.2M–$150M
Versant Ventures
VC Fund
9 United States, Switzerland, Canada Series A, Series B, Series C Biotechnology, Health Care, Medical $5M–$108M
Vivo Capital
VC Fund
9 United States, China, United Kingdom Post-IPO Equity, Series B, Series C Biotechnology, Health Care, Pharmaceutical $28M–$180M
Rev1 Ventures
VC Fund
9 United States, Germany Seed, Series A Software, Health Care, Information Technology $192k–$18M
iSelect Fund
VC Fund
8 United States, Canada, Australia Seed, Series A, Series B Biotechnology, Health Care, Agriculture $100k–$68M
Access all 3281 VC funds in United States Life Science startups.

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822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

ARCH Venture Partners
VC Fund · Chicago, Illinois, United States · 40 investments in United States Life Science startups

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 432
  • Round size: Series A $10M–$216M; Series B $14M–$250M; Series C $15M–$167M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • Synchron — The endovascular brain computer interface.
  • Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.
  • LifeMine Therapeutics — LifeMine is a clinical-stage biopharmaceutical company pioneering a bold new approach, Top-Down Drug DiscoveryTM, which leverages evolutionary insights from fungi to unearth next-generation precision medicines.
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Alexandria Venture Investments
VC Fund · Pasadena, California, United States · 29 investments in United States Life Science startups, 18 in the past 12 months

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Seed
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 270
  • Round size: Seed $2M–$31M; Series A $12M–$100M; Series B $25M–$150M
  • Lead/follow: 7% lead, 93% follow

Portfolio highlights

  • Triveni Bio — Triveni Bio is at the forefront of human genetics, cutting-edge antibody design, and precision medicine, pioneering the identification of new disease targets.
  • Vedana Therapeutics — Vedana Therapeutics is a Seattle biotechnology company developing next-generation antibody therapies for migraine prevention.
  • CREATE Medicines — Myeloid Therapeutics is an immunology company focused on combining immunologic insights with cutting-edge technologies to harness myeloid cells to eradicate cancer and other diseases. The Company's ATAKTM platform technology can be broadly applied, and it is initially advancing a cell therapy program for T cell lymphoma and a primed monocyteapproach to treat glioblastoma. The ATAK platform is scalable to multiple treatment modalities and other disease areas in collaboration with partners.
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Alumni Ventures
VC Fund · Manchester, New Hampshire, United States · 23 investments in United States Life Science startups

Access curated startup investment opportunities and diversified venture capital exposure designed for accredited investors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 2214
  • Round size: Seed $1.5M–$10M; Series A $5.5M–$35M; Series B $12M–$79M
  • Lead/follow: 5% lead, 95% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • WINN.AI — WINN.AI helps revenue teams run better sales calls and win more deals by automating admin work and guiding reps live, during the call.
  • Car Body Lab — The easy way, online.
  • Perennial — Cloud Agronomics is the platform for soil carbon management.
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Third Rock Ventures
VC Fund · Boston, Massachusetts, United States · 22 investments in United States Life Science startups

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States

Investor stats

  • Total investments: 173
  • Round size: Series A $19M–$110M; Series B $11M–$190M; Series C $20M–$108M
  • Lead/follow: 47% lead, 53% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Corvia Medical — Corvia Medical is a medical device company, focuses on developing structural heart devices for the treatment of heart failure. The company develops InterAtrial Shunt Device (IASD), a transcatheter device designed to treat diastolic heart failure (DHF), also known as heart failure with preserved ejection fraction (HFpEF). It was founded in 2009and headquartered in Andover, Massachusetts.
  • NinePoint Medical — NinePoint Medical, Inc. is a transformational medical device company developing innovative, real-time, in vivo pathology devices. The company's first goal is to develop a device that enables remote pathology, or telepathology, which would facilitate immediate review of images during diagnostic procedures. This capability could potentiallyprovide physicians with immediately actionable information and eventually allow them to pursue therapeutic remedies at the time of diagnosis. This convergence of access, diagnosis and treatment during one procedure is expected to improve patient experiences and outcomes, improve the efficiency of care and provide important savings to the healthcare system. Headquartered in Cambridge, Mass., NinePoint is backed by Third Rock Ventures and Prospect Venture Partners.
  • CytomX Therapeutics — CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies. Their mission, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases.
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SOSV
VC Fund · Princeton, New Jersey, United States · 21 investments in United States Life Science startups, 75 in the past 12 months

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

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Investment focus

  • Industry: Biotechnology, Health Care, Software
  • Stage:Seed, Convertible Note, Pre-Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1482
  • Lead/follow: no public data

Portfolio highlights

  • MixRift — MIXRIFT - game developers specialized in Mixed Reality
  • unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
  • Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
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Northpond Ventures
VC Fund · Bethesda, Maryland, United States · 21 investments in United States Life Science startups

Northpond Ventures is a science-driven venture capital firm headquartered in Bethesda, Maryland. Our mission is to build a better tomorrow. Our investments are focused on life sciences, technology, and affiliated industries.

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Investment focus

  • Industry: Biotechnology, Health Care, Life Science
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 149
  • Round size: Series A $13M–$65M; Series B $10M–$95M; Series C $23M–$85M
  • Lead/follow: 58% lead, 42% follow

Portfolio highlights

  • Culture Biosciences — Culture Biosciences provides a platform of cloud-connected bioreactors, software tools, and process development services that support upstream bioprocess development for biotech and biopharma applications. The company’s offerings include remote experiment design, monitoring, and data analysis through an integrated cloud software interface pairedwith single-use bioreactors for microbial fermentation and cell culture experimentation. Its services encompass clone and strain screening, process optimization, characterization, and bioprocess modeling to help scientific teams refine and scale their workflows. Clients access real-time data and analytics to inform decisions and collaborate across teams using the platform’s tools. Culture Biosciences’s technology is used to advance development of therapeutics, synthetic biology products, and related bioprocesses. Culture Biosciences was founded in 2016 and is headquartered in San Francisco, California.
  • Mestag Therapeutics — Driving fibroblast-immune conversations in cancer and inflammatory diseases.
  • EnPlusOne Biosciences — EnPlusOne Biosciences provides innovative solutions for emerging RNA therapeutics.
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Atlas Venture
VC Fund · Cambridge, Massachusetts, United States · 21 investments in United States Life Science startups

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 437
  • Round size: Series A $3.5M–$92M; Series B $8M–$115M; Series C $6M–$95M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • E Ink — E Ink Corp. is a supplier of electronic paper display (EPD) technologies. Products made with E Ink's electronic ink are designed to possess a paper-like high contrast appearance, ultra-low power consumption, and a thin, light form. E Ink's technology is tailored for many consumer and industrial applications including handheld devices,watches, clocks, and public information and promotional signs.
  • Songbird — DropCatch.com helps you secure expiring domain names.
  • Ethyreal Bio — Ethyreal Bio is an early-stage biotechnology company developing precision, mechanism-driven therapies for thyroid diseases with high unmet medical needs.
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OrbiMed
VC Fund · New York, New York, United States · 19 investments in United States Life Science startups

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, Israel

Investor stats

  • Total investments: 653
  • Round size: Series A $10M–$150M; Series B $24M–$150M; Series C $18M–$183M
  • Lead/follow: 35% lead, 65% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • CardiAQ Valve Technologies — CardiAQ Valve Technologies (CVT), a privately held company, is developing innovative approaches to heart valve replacement and is initially focused on transcatheter mitral valve implantation (TMVI).
  • Sonendo — Sonendo developing innovative technologies to transform dentistry by Saving Teeth Through Sound Science®. The GentleWave® System shows significant improvements in clinical efficacy and practice efficiency when compared to standard root canal treatment.1,2, 3 Sonendo is the parent company of TDO® Software, the developer of the most widely usedendodontic practice management software in the world, designed to simplify practice workflow. TDO software seamlessly integrates practice management, imaging, social media, referral reporting, CBCT imaging, and offers built-in communication with the GentleWave System.
  • Acceleron Pharma — At Merck, we're following the science to tackle some of the world's greatest health threats. Get a glimpse of how we work to improve lives.
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Gaingels
VC Fund · New York, New York, United States · 18 investments in United States Life Science startups

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Mexico

Investor stats

  • Total investments: 1258
  • Round size: Seed $1M–$8.5M; Series A $5.5M–$37M; Series B $16M–$100M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • Quadient Accounts Receivable by YayPay — YayPay accounts receivable automation software helps businesses collect faster, forecast cash flow accurately, and improve payment process. Automate your AR
  • Sharper Sense — Neuromodulation for Clear Senses
  • Willow Wealth — Willow Wealth is an alternative investment platform focused on generating income streams for investors. Get exclusive access to private market investments.
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RA Capital Management
VC Fund · Boston, Massachusetts, United States · 18 investments in United States Life Science startups

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series B, Series C, Post-IPO Equity
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 518
  • Round size: Series B $27M–$152M; Series C $44M–$183M; Post-IPO Equity $35M–$240M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • EvodiaBio — EvodiaBio is a bio-industrial firm that creates natural, sustainable scents for the food and beverage industries. Founded in 2021 and is based in Copenhagen, Capital Region.
  • Nkarta Therapeutics — Nkarta seeks to improve upon the efficacy of cell therapy, making it more potent, better tolerated and more rapidly available to a broad population of patients with a variety of hematologic and solid tumor malignancies.While T-cell therapy, often known as CAR-T, has proven successful in certain cancer indications, its promise has been limited toa few hematologic malignancies and the side effects can be severe. Natural Killer cells are the immune system’s first responders against diseases and pathogens. Unlike T cells, they have an inherent ability to target tumor cells without genetic alteration, and therefore hold significant promise in the development of potent therapies that can be used more readily for diverse tumor types. Nkarta’s differentiated cell therapy approach is designed to boost and enhance the inherent power of Natural Killer cells to target and destroy tumor cells, while also offering a better tolerated safety profile.
  • Kinaset Therapeutics — Kinaset Therapeutics is a therapeutics company that focuses on the advancement of novel drugs in areas of unmet medical needs. The company was founded in 2020 and is headquartered in Medfield, Massachusetts.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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8VC
VC Fund · San Francisco, California, United States · 17 investments in United States Life Science startups

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies. The firm focuses on creating long-term economic and societal value through its investments across various sectors, including healthcare and logistics.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 574
  • Round size: Seed $2.5M–$13M; Series A $8M–$57M; Series B $17M–$175M
  • Lead/follow: 33% lead, 67% follow

Portfolio highlights

  • Saronic — Providing the most advanced and capable autonomous vessels in the maritime domain.
  • Ushur — Ushur is a cloud-based automation platform that automates service workflows in both the backend process and conversational interfaces.The company develops intelligent automation solutions that include, Ushur Virtual Customer Assistant, smart technology that automates proactive member, claimant, agent, or broker communications across virtually anychannel, reaching out to customers, understanding what they need, and automatically taking the next steps; Ushur SmartMail, a software that allows insurers to process high-volumes of the customer, agent and broker email automatically, allowing carriers to respond faster and efficiently; Ushur Flowbuilder, the web-based no-code builder allows claims, broker services, and customer support teams to build, deploy and track rich digital engagements that improve business agility and the customer experience while minimizing the burden on IT. By leveraging the company's Robotic Process Automation (RPA) and Language Intelligence Service Architecture (LISA), insurance companies can accelerating capital and time-intensive processes like claims, customer support, billing, and enrollment to digitally transform service workflows.
  • Starpath Robotics — Making fully reusable missions to the Moon and Mars possible.
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Google Ventures
VC Fund · Mountain View, California, United States · 17 investments in United States Life Science startups

GV supports innovative founders moving the world forward.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 1231
  • Round size: Seed $1.1M–$17M; Series A $6M–$101M; Series B $16M–$125M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: May invest from a new fund soon — raised $100M in 2014

Portfolio highlights

  • Gusto — Gusto develops web-based payroll solution for small- and medium-sized businesses. It operates an online platform that provides payroll, benefits, human resources, and integration services for employers and employees in the United States.Gusto offers health benefits and workers’ compensation benefits that include medical insurance, commuterbenefits, and 401(k) contributions as well as workers’ compensation insurance plans, time tracking, and integration services, and access to employees for processing payroll from web-enabled devices such as smartphones and tablets. It also provides access to employees and contractors to browse their previous pay stubs, review their payroll forms, verify their personal details, and statistics about their pay, tax payments and federal forms filing services, and security and support services.Gusto serves startups, coffee shops, doctors, creative agencies, lawyers, and boutiques. Edward Kim, Joshua Reeves, and Tomer London founded ZenPayRoll in 2011 that became Gusto, with its headquarters in San Francisco in California with an additional office in Denver in Colorado.
  • SolveAI
  • Smarterer — Individuals and Fortune 500 companies use Smarterer to help close the gap between the skills they have and the skills they need. Their dynamic assessment engine leverages the freshest crowdsourced tests around, to rapidly pinpoint skill level with a credible score. In November 2014, Pluralsight, the global leader in online learning for serioussoftware developers, IT specialists and creative technologists, acquired Smarterer. As the world's largest curated e-learning library for professionals, the company offers instant access to more than 3,500 courses authored by top experts. Smarterer will continue to power crowdsourced assessments for freelancer marketplaces, e-learning providers and enterprise companies anywhere people need to prove their skills to connect with professional opportunities. The Smarterer community has answered over 56 million during 1.7 million test sessions, across hundreds of tests.
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Andreessen Horowitz
VC Fund · Menlo Park, California, United States · 15 investments in United States Life Science startups

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

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Investment focus

  • Industry: Software, Information Technology, Artificial Intelligence
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Brazil

Investor stats

  • Total investments: 1910
  • Round size: Seed $1.7M–$20M; Series A $9M–$55M; Series B $17M–$112M
  • Lead/follow: 49% lead, 51% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • Mux — Mux helps teams ship high-performance and cost-effective video in minutes, not months. Build better video into anything from websites to platforms to AI workflows.
  • Slack — Slack is a cloud-based communication and collaboration platform for teams. It allows users to exchange messages, share files, and integrate with various business tools and services. Slack is commonly used across various industries, from tech startups to large enterprises.
  • Bigscreen — Founded by Darshan Shankar in 2014, Bigscreen is a venture-backed startup creating an immersive virtual reality platform that aims to revolutionize the way people work, play, hangout, and collaborate.Use cases of Bigscreen include both entertainment and productivity. Users love using Bigscreen as a "VR movie theater" to watch movies andTV shows. It's also used to play videogames, browse the web, and hangout with friends. It's can also be used for productivity as a tool for remote teams to collaborate together in virtual offices.Since the beta launch in March 2016, Bigscreen has become one of the most popular and highest rated VR apps on the Oculus Store and has an incredible 93% positive rating on Steam. Power users spend 20-30 hours per week in Bigscreen, making it one of the most widely used "killer apps" in the industry.Bigscreen is now the most popular non-gaming VR application in the world.Bigscreen is a fully distributed remote company with employees based around the world in the US & UK.
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Flagship Pioneering
VC Fund · Cambridge, Massachusetts, United States · 14 investments in United States Life Science startups, 8 in the past 12 months

We create breakthroughs in human health and sustainability and build bioplatform companies . Companies founded

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series C, Series A
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 229
  • Round size: Series A $6.5M–$75M; Series B $11M–$230M; Series C $12M–$123M
  • Lead/follow: 43% lead, 57% follow
  • Last fund: Likely still investing — fund raised in 2024

Portfolio highlights

  • Expedition Medicines — Defining a new era in drug discovery where chemistry rewrites the rules of biology to engage any protein target.
  • Foghorn Therapeutics — Foghorn Therapeutics is developing therapies based on a system that directs which genes our cells express, and when, where, and in what order.By manipulating this system with our unique Gene Traffic ControlTM platform, Foghorn will change how genes turn “on” and “off.” Unlike approaches that edit genes, this novel way of thinking will alter whatour DNA has in store for us—and rewrite destiny for millions of people living with disease.With Gene Traffic ControlTM Foghorn is pioneering a new, major class of drug targets to develop unprecedented therapies for cancer and other serious diseases. We have already validated multiple targets, are in the process of developing drug candidates in multiple types of cancer and are beginning to explore other diseases.
  • Serif Bio­med­i­cines — Serif Biomedicines is pioneering Modified DNA as a new type of biotechnology. Serif combines nucleic acid chemistry, synthetic biology, delivery technology, and artificial intelligence to develop programmable, scalable, long-lasting, and redosable DNA therapies.
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Novartis Venture Fund
VC Fund · Basel, Basel-Stadt, Switzerland · 14 investments in United States Life Science startups

Learn about the approach the Novartis Venture Fund takes to investing in innovative life science companies developing biotechnology and biopharmaceutical therapeutics that address unmet patient needs.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series B, Series A, Series C
  • Geography: United States, Switzerland, United Kingdom

Investor stats

  • Total investments: 219
  • Round size: Series A $5.1M–$81M; Series B $11M–$120M; Series C $9M–$75M
  • Lead/follow: 26% lead, 74% follow
  • Last fund: May invest from a new fund soon — raised $200M in 2009

Portfolio highlights

  • Bionano Genomics — Discover how Bionano is striving to elevate health and wellness for all through optical genome mapping (OGM) solutions that transform the way the world sees the genome.
  • Protego Biopharma — Protego Biopharma develops therapeutics based on the clear human genetic link, excellent human safety profile, proof-of-principle efficacy. The company was founded in 2011 and is headquartered in San Diego, California.
  • Twentyeight-Seven Therapeutics — Maxslot88 merupakan link situs slot gacor gampang menang jackpot maxwin hari ini sebagai daftar apk slot88 terpercaya dengan server thailand resmi, memberikan pengalaman bermain slot online yang aman dan menghibur bagi semua klien.
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DCVC
VC Fund · San Francisco, California, United States · 14 investments in United States Life Science startups

We are deep tech venture capital.

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Investment focus

  • Industry: Software, Artificial Intelligence, Machine Learning
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 404
  • Round size: Seed $1.5M–$9.1M; Series A $5.8M–$50M; Series B $15M–$139M
  • Lead/follow: 24% lead, 76% follow
  • Last fund: Likely still investing — raised $1B in 2023

Portfolio highlights

  • Sabanto — Sabanto brings autonomy to agriculture with retrofit kits that transform existing tractors into fully autonomous machines. Boost efficiency, reduce labor, and farm 24/7 with the Sabanto Autonomy System. Book a demo today.
  • CH4 Global — CH4 Global is an aquaculture solutions provider dedicated to urgently impacting climate change at scale. Lead by a world-class team of senior business builders, scientists and entrepreneurs, the company is initially leveraging proven science and technology for growing seaweed into innovative new livestock supplement that reduces methane produced bycows by up to 90%. Among early investors are a select group of prominent family offices and private investors. CH4 Global have also received non-dilutive capital support from government organizations from around the world. CH4 Global is a Delaware corporation based in Henderson, NV.
  • Tradeshift — Tradeshift is a supply chain network, Tradeshift is a market leader in e-invoicing and accounts payable automation and an innovator in supplier financing and B2B marketplaces.
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The Column Group
VC Fund · San Francisco, California, United States · 13 investments in United States Life Science startups

The Column Group (TCG) is a venture ecosystem dedicated to fueling scientific innovation in the life sciences industry.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States

Investor stats

  • Total investments: 150
  • Round size: Series A $15M–$102M; Series B $22M–$120M; Series C $37M–$120M
  • Lead/follow: 37% lead, 63% follow

Portfolio highlights

  • Immune Design — Immune Design Corp. (IDC) uses breakthrough technology to develop safe and effective vaccines and therapeutics, with emphasis on the prevention and treatment of infectious disease. This goal is being achieved through dedicated research aimed towards a greater understanding of the immune system, and by developing a new generation of immune-basedproducts for the pharmaceutical industry. IDC is passionate about its mission to alleviate human suffering and pursues this goal with high energy and an unsurpassed standard of excellence
  • Carmot Therapeutics — Breakthrough science. One moment, one day, one person at a time.
  • Constellation Pharmaceuticals — Constellation Pharmaceuticals is the first biopharmaceutical company dedicated to the development of novel therapeutics in the emerging field of Epigenetics, a new field of science which is focused on selective regulators of epigenetic function, which are critical to controlling gene expression.
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Alix Ventures
VC Fund · San Francisco, California, United States · 13 investments in United States Life Science startups

Supporting early stage Life Science startups driving patient impact. Born from our collective experience as founders, we set out to build the fund we wanted to raise from....

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Investment focus

  • Industry: Health Care, Biotechnology, Life Science
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States

Investor stats

  • Total investments: 23
  • Round size: Seed $2M–$12M; Pre-Seed $2.7M–$2.7M; Series A $12M–$70M
  • Lead/follow: 13% lead, 87% follow

Portfolio highlights

  • iOrganBio — The Right Cells. Consistently. At Scale.
  • Galatea Bio — Galatea Bio, a US-based biotechnology company was founder by Carlos Bustamante, Nicholas Katsanis and Alexander Ioannidis. Our mission is to drive groundbreaking discoveries in healthcare by pairing genetic diversity with cutting-edge data analytics. Our passion is fueled by a focus on populations historically underrepresented in genetics research.We achieve this by leveraging our world-class clinical network and biobank, cutting-edge algorithms, and innovative analyses to discover and validate new tests, treatments, and cures that will improve the lives of all.
  • Italic Health — Italic Health, Inc. is a healthcare technology company building a unified platform for managing patient data, medical billing, and insurance workflows. Its software integrates health records, appointment scheduling, and AI-driven analytics to improve care coordination, financial processes, and patient engagement.
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KdT Ventures
VC Fund · Austin, Texas, United States · 13 investments in United States Life Science startups

KdT Ventures is the standard for early-stage frontier science investing.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Seed, Series A, Series B
  • Geography: United States, India, Canada

Investor stats

  • Total investments: 94
  • Round size: Seed $2.6M–$13M; Series A $9M–$70M; Series B $25M–$175M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: Likely still investing — raised $80M in 2022

Portfolio highlights

  • Zag Bio — Zag Bio is harnessing the immune system in a whole new way by targeting the thymus to change treatment possibilities for millions of patients with autoimmune diseases.
  • Skeletalis — Skeletalis is a biotechnology startup focused on developing next-generation precision medicines for musculoskeletal diseases, primarily osteoporosis.
  • Tacit Therapeutics — New broadly-applicable and non-immunogenic RNA gene therapy that can treat thousands of devastating illnesses.
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Fifty Years
VC Fund · San Francisco, California, United States · 12 investments in United States Life Science startups

WE BACK HEROES using technology to solve the world's biggest problems

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Investment focus

  • Industry: Biotechnology, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Germany, Canada

Investor stats

  • Total investments: 184
  • Round size: Seed $2M–$15M; Series A $8.5M–$37M; Series B $16M–$91M
  • Lead/follow: 17% lead, 83% follow
  • Last fund: Likely still investing — raised $90M in 2021

Portfolio highlights

  • Gridware — Using remote telemetry and edge AI, Gridware wildfire prevention technology powers a grid that is smarter and more reliable than ever before.
  • Onepot.ai — Search 2.7 billion make-on-demand analogs from onepot CORE, get a quote, and we synthesize and QC them in our US-based lab. AI-powered custom synthesis CRO.
  • Adaption Labs — Adaptation creates AI systems that adjust to changing real-world circumstances.
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Felicis
VC Fund · Menlo Park, California, United States · 12 investments in United States Life Science startups

Backing founders building iconic companies that transcend boundaries

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Investment focus

  • Industry: Software, Artificial Intelligence, SaaS
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, Germany

Investor stats

  • Total investments: 612
  • Round size: Seed $1.5M–$15M; Series A $4.4M–$46M; Series B $10M–$76M
  • Lead/follow: 28% lead, 72% follow

Portfolio highlights

  • Midi Health — Expert care for women 40+. Made for midlife. Delivered by experienced clinicians. Covered by insurance. Book a visit today.
  • Petasense — Founded with a vision of making industrial machines smarter, Petasense is an Industrial IoT startup based in Silicon Valley. The company offers an end-to-end solution – comprised of a patent-pending wireless vibration sensor, cloud software and machine learning analytics – that helps with asset reliability and predictive maintenance. Customersare able to monitor, assess and predict the health of their critical machines in real-time. This helps them reduce unplanned downtime and lower repair costs. Petasense's clients include industry leaders like JLL, C&W Services, Silicon Valley Power and Stanford University. Petasense is backed by True Ventures, Felicis Ventures and top angel investors. The company is founded by serial entrepreneurs, Abhinav Khushraj and Arun Santhebennur, who have 25 years of combined experience in building enterprise companies, with degrees from MIT and IIT.To learn more about Petasense, visit www.petasense.com.
  • ConductorOne — C1 equips security and IT teams with a powerful autonomous identity security platform. Secure access with complete visibility, just-in-time provisioning, automated access reviews, and more.
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Apple Tree Partners
VC Fund · New York, New York, United States · 12 investments in United States Life Science startups

ATP, a global leader in life sciences venture capital, is developing the next generation of transformative biotechnology companies. ATP creates science-based companies starting with assets at various stages: from working with scientists on pre-IP ideas, to spinouts from existing company pipelines. The firm provides flexible capital, strategicinsight, and operational resources to build sustainable, research-driven enterprises. ATP invests in its portfolio companies from seed stage through IPO and beyond and supports their management teams in strategic transactions and synergistic business combinations.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Seed
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 91
  • Round size: Seed $3.5M–$8M; Series A $20M–$75M; Series B $29M–$100M
  • Lead/follow: 63% lead, 37% follow
  • Last fund: May invest from a new fund soon — raised $1B in 2020

Portfolio highlights

  • Ascidian Therapeutics — Ascidian Therapeutics is a biotechnology company intended for medical use in medical and clinical gene therapy.
  • Red Queen Therapeutics — Staying ahead of viral threats with new innovations in antiviral therapy
  • Deep Apple Therapeutics — Deep Apple Therapeutics is discovering new small-molecule therapeutics with unprecedented speed and exceptional acumen.
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General Catalyst
VC Fund · Cambridge, Massachusetts, United States · 12 investments in United States Life Science startups

Investing in powerful, positive change that endures

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 2051
  • Round size: Seed $2M–$20M; Series A $7M–$75M; Series B $14M–$130M
  • Lead/follow: 46% lead, 54% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • Datalogix — Datalogix® is the industry-recognized leader at connecting digital media and offline purchasing data. We help more than half of the top 100 consumer marketers increase the effectiveness and measurability of their advertising. DLX Platform®, encompasses over $1 trillion in consumer spending and powers campaigns for more than 75% of online mediacompanies. DLX ROI® is rapidly becoming the industry standard for measuring offline sales lift for digital media. Datalogix also offers predictive analytics for Direct Mail, and integrated media solutions via the DLX Net. Our expertise spans the major consumer segments, including Retail, CPG, Automotive, Telecom, Travel and Financial Services. We are based in Colorado, with offices in New York City, San Francisco, Boston, Chicago, Detroit, and London.
  • Legora — By streamlining and simplifying legal workflows, we empower elite law firms and legal professionals to work more efficiently and effectively. Enabling them to focus on higher-value tasks and deliver exceptional results for their clients.
  • Ramp — Join thousands of forward-thinking businesses using Ramp to control spend, save time, and automate busywork.
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Lux Capital
VC Fund · New York, New York, United States · 12 investments in United States Life Science startups

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 613
  • Round size: Seed $1.8M–$30M; Series A $7.4M–$96M; Series B $14M–$150M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: May invest from a new fund soon — raised $100M in 2007

Portfolio highlights

  • Toonimo — Toonimo humanize the web user experience with an engaging and personalized step-by-step interactive walkthrough
  • Kyruus Health — Kyruus Health is the leading care access platform on a mission to connect people to the right care.
  • Cajal Neuroscience — Cajal Neuroscience is a drug discovery company focused on neurodegenerative disease.
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Civilization Ventures
VC Fund · San Francisco, California, United States · 12 investments in United States Life Science startups

DIGITAL HEALTH / AI DIGITAL HEALTH / AI GENE / CELL THERAPIES NASDAQ: RCKT GENE / CELL THERAPIES NASDAQ: RCKT GENOMICS / DIAGNOSTICS GENOMICS / DIAGNOSTICS SYNTHETIC

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Brazil

Investor stats

  • Total investments: 74
  • Round size: Seed $1.8M–$16M; Series A $8.1M–$30M; Series B $24M–$144M
  • Lead/follow: 3% lead, 97% follow

Portfolio highlights

  • OxCan — Enabling curative cancer treatment through early detection
  • Foresight Diagnostics — We develop innovative diagnostics to advance decision-making in oncology drug development and patient care.
  • Rinascera Therapeutics — Rinascera Therapeutics develops transformative therapies for rare genetic skin diseases, including RIN-001 for Gorlin Syndrome and RIN-002 for Dystrophic Epidermolysis Bullosa (DEB).
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Sahsen Ventures
VC Fund · Seattle, Washington, United States · 11 investments in United States Life Science startups

Sahsen Ventures is a venture capital firm making investments in for-profit and nonprofit organizations with an emphasis on technology and biotechnology. It was established in 2016 and is based in Seattle, Washington.

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Investment focus

  • Industry: Biotechnology, Health Care, Non Profit
  • Stage:Seed, Series A
  • Geography: United States, China, Ghana

Investor stats

  • Total investments: 87
  • Round size: Seed $1.2M–$25M; Series A $13M–$81M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Synthesize Bio — Deep biomedical data is the key to unlocking discoveries and creating therapies. Synthesize Bio uses AI to reduce data collection and analysis from months to minutes for a fraction of the cost in time, personnel, and materials.
  • Archon Biosciences — Archon is a biotechnology firm that creates computationally engineered proteins to unleash potent therapeutic targets beyond the grasp of current methods and improve disease management.
  • ZymeCO — ZymeCO is a bio-manufacturing company that develops enzyme-based biological products designed for sustainable agriculture and turf management. The company utilizes a bio-process that transforms organic matter to build soil health, accelerate residue decomposition, and boost plant growth.
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Omega Funds
VC Fund · Boston, Massachusetts, United States · 11 investments in United States Life Science startups

We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, United Kingdom

Investor stats

  • Total investments: 161
  • Round size: Series A $16M–$187M; Series B $37M–$162M; Series C $14M–$208M
  • Lead/follow: 27% lead, 73% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Attenua — 100% satisfaction guaranteed. Hassle-free shopping. We help you find the right domain name.
  • Andrew Alliance — OneLab is laboratory software to design and execute liquid handling protocols. Pipette+ for manual liquid handling pipetting and Andrew+ the pipetting robot
  • Chord Therapeutics — Chord Therapeutics is a clinical stage pharmaceutical company developing drugs for patients with rare, life-threatening and severely disabling diseases. We are advancing our lead drug candidate CRD1 under orphan drug designation for the treatment of neuromyelitis optica spectrum disorders (NMOSD) and myasthenia gravis (MG).
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Catalio Capital Management
VC Fund · Baltimore, Maryland, United States · 11 investments in United States Life Science startups

Catalio Capital Management was created by George Petrocheilos and Dr. Jacob Vogelstein to invest in breakthrough biomedical technology companies created or referred by Catalio Capital Management, an elite group of world-renowned, serial scientist-entrepreneurs.

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Investment focus

  • Industry: Biotechnology, Health Care, Life Science
  • Stage:Series A, Series B
  • Geography: United States, Switzerland, Israel

Investor stats

  • Total investments: 142
  • Round size: Series A $15M–$150M; Series B $26M–$130M
  • Lead/follow: 31% lead, 69% follow

Portfolio highlights

  • OSPRI — Multiplex qPCR reagent kits for assay development, biomarker discovery, and translational research. 120+ configurations across a broad range of research areas. Extraction-free. Customizable. For Research Use Only.
  • Ratio Therapeutics — Ratio is a privately held discovery-stage biotechnology company that utilizes a suite of technologies licensed from Cornell University to develop best-in-class targeted radiotherapeutics for the treatment of metastatic cancers.
  • Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.
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Liquid 2 Ventures
VC Fund · San Francisco, California, United States · 11 investments in United States Life Science startups

Liquid2 Ventures provides technology startups with seed-stage investments and is based in San Francisco, California. The firm was founded in 2015 by Joe Montana, Mike Miller, and Michael Ma.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States, Mexico, Canada

Investor stats

  • Total investments: 867
  • Round size: Seed $1.6M–$10M; Pre-Seed $125k–$3M; Series A $6M–$50M
  • Lead/follow: 1% lead, 99% follow

Portfolio highlights

  • Albedo — Aerial quality imagery - from space.
  • Eden — Developer of non-invasive health technology designed to democratize access to early cancer risk assessment.
  • Attention — Attention is building an AI co-pilot designed to automate repetitive, multi-app desktop tasks.
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Artis Ventures
VC Fund · San Francisco, California, United States · 11 investments in United States Life Science startups

Artis Ventures has spent over a decade backing bold teams who take the hard path, building market-defining companies to re-shape, re-invent, and re-make industries.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 145
  • Round size: Seed $2M–$47M; Series A $5M–$57M; Series B $20M–$127M
  • Lead/follow: 38% lead, 62% follow

Portfolio highlights

  • Ozlo Sleep — Ozlo Sleep is a science-driven sleep and audio technology company that supports and simplifies sleep rituals for clinical benefits, without the use of medication.
  • Arkenstone Defense — Arkenstone Defense provides an operating infrastructure platform that integrates government contracting and regulatory compliance into a centralized system for commercial technology companies. The platform manages complex defense requirements, including cleared workforce payroll, personnel security, audit readiness, and technical accreditationframeworks like CMMC and FedRAMP. By embedding these back-office operational controls directly into client environments, the company eliminates the administrative barriers that prevent commercial innovators from selling to the federal market.
  • Stateless Networks — Performance, Visibility. Simplicity...It's time for a beautiful network. Stateless is transforming network operations for software-centric networking. Tying together deep network understanding with state-of-the-art distributed systems, cloud, data science and gaming expertise, Stateless transforms network visibility, performance andresponse and helps accelerate the transition to modern network platforms, tying together physical and virtual layers. Focused on the enterprise data center, Stateless currently partners with the world’s leading network and infrastructure vendors (including VMware (VMW), Cisco Systems (CSCO), Cumulus Networks and others) to deliver solutions to some of the world’s largest private data center operators. We’re looking for software and networking engineers in Greater Seattle and the Bay Area with expertise in one or more of the following areas: Distributed Systems, Service Oriented Architecture, Complex Event processing, Functional Programming, Virtualization, Network design and deployment, Network programming, Network troubleshooting, configuration and performance tuning and SDN. Bonus points for experience working with cloud infrastructure (AWS, Azure, OpenStack) or low-level systems software (linux kernel, hypervisors, compilers/language runtimes), complex gaming systems or graphics and computational geometry. For more information visit http://www.statelessnetworks.com/ or follow Stateless on Twitter: @statelessntwrks.see
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MPM Capital
VC Fund · Cambridge, Massachusetts, United States · 11 investments in United States Life Science startups

Powering Breakthroughs in Life Sciences

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Series B, Series A, Series C
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 229
  • Round size: Series A $10M–$80M; Series B $20M–$116M; Series C $12M–$100M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely still investing — raised $850M in 2021

Portfolio highlights

  • Orna Therapeutics — Orna Therapeutics is a biotechnology company dedicated to designing and delivering a new class of fully engineered circular RNA (oRNA) therapeutics with the potential to change the way we treat disease. Orna’s proprietary platform combines novel technology to create oRNAs that drive protein expression with validated and unique delivery solutions.
  • Aratana Therapeutics — Aratana is uniquely positioned to deliver new, high-quality medicines to address unmet needs in companion animal care. We are committed to bringing world class science to animal health for companion animals and the people who care for them. Our competitive advantage resides in our ability to identify, acquire and develop high-value commercialproducts for companion animals in a cost effective and efficient manner.
  • Rhythm Pharmaceuticals — Rhythm Pharmaceuticals is a global biopharmaceutical company committed to transforming the lives of patients with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.
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Cormorant Asset Management
VC Fund · Boston, Massachusetts, United States · 11 investments in United States Life Science startups

Cormorant Asset Management is an employee-owned hedge fund sponsor that provides its services to pooled investment vehicles. The firm also focuses on both public and private market innovative companies in the biotechnology and life sciences marketplace.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series C, Series A
  • Geography: United States, China, Switzerland

Investor stats

  • Total investments: 217
  • Round size: Series A $16M–$115M; Series B $30M–$150M; Series C $30M–$146M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: May invest from a new fund soon — raised $393M in 2019

Portfolio highlights

  • Processa Pharmaceuticals — Founded in Oct '17 with a mission to develop products that can improve the survival and/or quality of life for patients who have a high unmet medical need.
  • Cue Biopharma — A precision immuno-engineering company targeting transformative therapies for patients with significant unmet needs across allergic and autoimmune diseases.
  • Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.
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F-Prime
VC Fund · Cambridge, Massachusetts, United States · 11 investments in United States Life Science startups

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 455
  • Round size: Series A $9.2M–$100M; Series B $15M–$112M; Series C $22M–$150M
  • Lead/follow: 27% lead, 73% follow

Portfolio highlights

  • ReadMe — Make your APIs easy to use and your developers successful.
  • Axle Health — Axle Health provides scheduling and workforce management software to help home healthcare and hospice providers improve their clinician productivity.
  • Mersana Therapeutics — Discover how Day One is disrupting the status quo of traditional drug development to bring new medicines to children and adults with cancer.
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Digitalis Ventures
VC Fund · New York, New York, United States · 11 investments in United States Life Science startups

Engineering solutions to complex problems in health through venture investment and company creation.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 113
  • Round size: Seed $1.5M–$15M; Series A $8.6M–$66M; Series B $13M–$132M
  • Lead/follow: 14% lead, 86% follow

Portfolio highlights

  • Somatix — A fully comprehensive monitoring solution with unique smartband technology. Solutions for SNFs, senior living, healthcare systems, and smoking cessation.
  • Girihlet — Girihlet is a provider of rapid and accurate deep sequencing services with a unique focus on developing novel technologies. Girihlet currently specializes in inexpensively sequencing and analyzing mtDNA and T cell receptors using novel, bias-free methods in order to harness their power as biomarkers for diagnostics in a variety of disorders.
  • Omni — Omni provides Healthy Vegan Dog Food in the UK, made by vets to be a nutritionally complete meal for your dog. Feed your dog all the goodness of plants backed by science.
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Foresite Capital
VC Fund · San Francisco, California, United States · 11 investments in United States Life Science startups

We are a multi-stage investment firm, investing in companies that leverage biology and big data to transform healthcare.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series B, Series C, Series A
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 195
  • Round size: Series A $22M–$165M; Series B $25M–$140M; Series C $38M–$270M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: Likely still investing — fund raised in 2024

Portfolio highlights

  • Stepful — New York City, 100% Job Guarantee, Online, 4 months, Part-Time, $166 per month
  • Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.
  • Aeovian Pharmaceuticals — Aeovian is a San Francisco based biopharmaceutical company developing novel and highly selective therapeutics modulating mTORC1 pathway.
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Hatteras Venture Partners
VC Fund · Durham, North Carolina, United States · 11 investments in United States Life Science startups

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Canada

Investor stats

  • Total investments: 134
  • Round size: Series A $8.2M–$50M; Series B $5M–$90M; Series C $8M–$88M
  • Lead/follow: 37% lead, 63% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Ribometrix — The Next Frontier of Drug Discovery
  • G1 Therapeutics — G1 Therapeutics is a clinical-stage company developing novel cancer therapies. It was founded in 2008 by Drs. Norman Sharpless and Kwok-Kin Wong to capitalize on discoveries made and patented by Dr. Sharpless’ lab at the University of North Carolina at Chapel Hill, and subsequently licensed to G1 Therapeutics. Trilaciclib is an investigationaltherapy designed to improve outcomes for people with cancer who are treated with chemotherapy. G1 is also advancing rintodestrant, a potential best-in-class oral selective estrogen receptor degrader, or SERD, for the treatment of ER+ breast cancer.
  • Viamet Pharmaceuticals — Viamet Pharmaceuticals discovers and develops "best-in-class" inhibitors of validated metalloenzymes via an innovative and proprietary metal-binding approach, their Metallophileâ„¢ Technology. Viamet's disruptive Metallophileâ„¢ technology is based on their world-class expertise in bioinorganic chemistry and metalloenzymes and allowsthem to identify validated targets with high therapeutic and commercial potential; leverage existing metalloenzyme inhibitors as the basis for Viamet's best-in-class analogs; and rapidly and cost-effectively generate best-in-class, patentable, small molecule compounds by optimizing the metal-binding component of existing inhibitors.
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SR One
VC Fund · Cambridge, Massachusetts, United States · 10 investments in United States Life Science startups

SR One Capital Management is a leading trans-Atlantic biotech venture capital firm that partners with top entrepreneurs, scientists and investment partners to seek to build elite biotechnology companies. Our mission is to translate ground-breaking technologies into next generation medicines to benef

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 198
  • Round size: Series A $3.7M–$100M; Series B $15M–$114M; Series C $22M–$175M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • CHARM Therapeutics — CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins.
  • Addition Therapeutics — Addition Therapeutics focuses on developing RNA-only therapeutics using its proprietary PRINT technology. This approach enables the precise insertion of genetic elements at specific safe harbor sites, aiming to transform the field of genetic medicine. They operate within the biotechnology industry and are backed by venture capital. Their innovativemethods target gene editing and regulation, potentially offering new solutions in the field of genetic therapies.
  • Morphic Therapeutic — Morphic Therapeutic is a biotechnology company developing a new generation of oral integrin therapies. Drawing on discoveries made in the lab of Scientific Founder Tim Springer, Morphic was created in 2015 with co-founders Polaris Partners, T.A. Springer and Schrödinger, Inc., along with ShangPharma Investment Group.
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Longwood Fund
VC Fund · Boston, Massachusetts, United States · 10 investments in United States Life Science startups

Longwood creates and invests in science-based companies that develop novel solutions for important medical problems

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Investment focus

  • Industry: Biotechnology, Therapeutics, Health Care
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Italy

Investor stats

  • Total investments: 77
  • Round size: Series A $16M–$100M; Series B $25M–$152M; Series C $17M–$100M
  • Lead/follow: 16% lead, 84% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Recros Medica — Recros Medica, Inc. is a development stage medical aesthetic device company focused on developing a platform technology to reduce skin laxity and improve focal aesthetic contour deformities. The company was incorporated in 2014 and is based in San Diego, California.
  • AAVantgarde Bio — AAVantgarde is a clinical-stage biotechnology company developing next-generation therapies for inherited retinal diseases with high unmet need
  • Coultreon Biopharma — Coultreon Biopharma is a clinical-stage biotech company developing next-generation precision medicines for immunology and autoimmune disease. Our pipeline targets SIK3 to deliver transformative therapies where unmet need remains high.
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Connecticut Innovations
VC Fund · Rocky Hill, Connecticut, United States · 10 investments in United States Life Science startups

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 267
  • Round size: Seed $300k–$6M; Series A $2.4M–$25M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: Likely still investing — raised $50M in 2023

Portfolio highlights

  • eBrevia — Analyze contracts at scale, extract key data, and identify risk with eBrevia. Draft and redline agreements in Microsoft Word with DraftPro.
  • Mobile Sense — The traditional diagnostic market is being transformed by advances in high performance wearables. This seismic shift led by consumer products which are uncovering new patients who previously went undetected, but still require a detailed diagnosis. Mobile Sense™ is building foundational technology that enables this transformation throughoff-the-chest wearables for long term management of cardiac arrhythmias. Developed over 7 years with $4.2M in grant funding and $1.3M in seed funding, Mobile Sense™ has a platform for differentiated wearables. Our embedded algorithms coupled with non-adhesive, wireless & waterproof sensors provides high fidelity continuous ECG and PPG recordings. The automatic monitoring provides 24/7, 365 days/yr continuous detection and classification of dangerous heart arrhythmias.
  • LegiTime Technologies — LegiTime Technologies, Inc. provides LegiText, a subscription-based SMS solution that offers message authentication, categorization, and archiving based on demonstration of legitimacy technology. It also provides LegiTrac that locates and tracks devices, as well as back up and stores data in a central location; and LegiAlert that offers messagebroadcasts and alerts, creates groups and contact lists, and integrates contact information with existing back office data systems. The company serves enterprises and educational institutions, as well as consumer, finance and banking, and healthcare industries. LegiTime Technologies, Inc. was founded in 2005 and is based in Farmington, Connecticut.
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TBD Angels
VC Fund · Boston, Massachusetts, United States · 10 investments in United States Life Science startups

TBD Angels is a group of like-minded angel investors who thrive on sharing advice, guidance, and capital with talented entrepreneurs. TBD Angels provide critical advice and connections to jumpstart the companies it invests in.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Pre-Seed, Angel
  • Geography: United States, Kenya, Hong Kong

Investor stats

  • Total investments: 92
  • Round size: Seed $334k–$6M; Angel $54k–$3M; Pre-Seed $200k–$16M
  • Lead/follow: 5% lead, 95% follow

Portfolio highlights

  • Penny Finance — Get a tailored financial & investing plans, track your money making, learn about personal finances & get new insights, all in the Penny Finance investing app for women.
  • Yuva Biosciences — Using cutting edge mitochondrial science to develop cosmeceuticals and pharmaceuticals.
  • Cayuga Biotech — Cayuga Biotech is a startup developing novel hemostatic drugs and devices to reduce uncontrollable bleeding which is a leading cause of death from traumatic injuries. The company's polyphosphate-based drug accelerates the body's own clotting process to contain clotting at the injury site and thus minimize the risk of side effects. Cayugais developing drugs for indications that treat traumatic hemorrhage as well as rare bleeding disorders.
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Pear VC
VC Fund · Palo Alto, California, United States · 10 investments in United States Life Science startups

Pear VC partners with entrepreneurs from day zero to build category-defining companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, Brazil, Spain

Investor stats

  • Total investments: 422
  • Round size: Seed $2M–$9M; Pre-Seed $500k–$3.7M; Series A $8M–$40M
  • Lead/follow: 19% lead, 81% follow
  • Last fund: Likely still investing — raised $432M in 2023

Portfolio highlights

  • WindBorne Systems — WindBorne designs, builds, and operates a constellation of long-duration smart weather balloons targeting the most critical data in the atmosphere.
  • Nightfall — Nightfall is one trusted DLP platform to discover, classify, and protect sensitive data across SaaS and cloud apps with machine learning.
  • Foresight Diagnostics — We develop innovative diagnostics to advance decision-making in oncology drug development and patient care.
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Biotechnology Value Fund
VC Fund · San Francisco, California, United States · 10 investments in United States Life Science startups

Biotechnology Value Fund is a San Francisco-based private investment partnership specializing in fundamentally-driven public biotechnology investments.Since its inception in 1993, BVF has strived to build concentrated, long-term investments in small-cap biotechnology companies while performing rigorous diligence and on-going monitoring of itsinvestments.BVF is committed to working with its portfolio companies as partners in their successes.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Post-IPO Equity, Series B, Series A
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 169
  • Round size: Series A $8.9M–$177M; Series B $40M–$140M; Post-IPO Equity $20M–$200M
  • Lead/follow: 28% lead, 72% follow

Portfolio highlights

  • BiolineRx — BioLineRx is building a best-in-class pipeline designed to deliver meaningful therapeutic benefit to patients with certain cancers and rare diseases.
  • Contraline — Contraline is a medical device company that has developed a proprietary injectable hydrogel platform for use in reproductive and contraceptive applications. Contraline's first product, Adam, is implanted into the vas deferens through a minimally invasive, outpatient procedure and once implanted, the gel effectively blocks sperm. Adam isnon-hormonal, designed to last years, and easily reversible.
  • Entera Bio — Entera Bio is developing novel oral drugs by utilizing its proprietary cutting edge delivery technology This technology protects large molecules and peptides in the GI tract. Oral drug delivery is the most straight forward and user friendly approach to medical treatment. Entera Bio has key personnel with the relevant know how, experience andnetworks working together to enable rapid development of its products. The company has an experienced management team with more than 50 years of combined drug development experience.
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Two Sigma Ventures
VC Fund · New York, New York, United States · 10 investments in United States Life Science startups

We are an early-stage venture capital firm investing in transformative companies harnessing information growth and computing power to change the world.

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Investment focus

  • Industry: Software, Artificial Intelligence, Machine Learning
  • Stage:Series A, Series B, Seed
  • Geography: United States, Canada, Mexico

Investor stats

  • Total investments: 222
  • Round size: Seed $2.2M–$9M; Series A $7.5M–$70M; Series B $15M–$120M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: Likely still investing — raised $400M in 2022

Portfolio highlights

  • Wealthsimple — Being better than a bank means more of everything. Spend, trade and invest with Wealthsimple.
  • Ansel Health — Give your employees peace of mind with supplemental health insurance from Brella. Our plan offers more coverage, less hassle, and a faster, simpler claims experience.
  • littleBits Electronics — LittleBits is an open source library of over 60 electronic modules that snap together with magnets allows users to view, download, and share designs and make their own Bits through the use of prototypes. Deluxe kit, Smart home kit, Arduino coding kit, Synth kit, hardware development kit, and workshop set are some of the electronics learning modulesprovided by littleBits.LittleBits was launched by Ayah Bdeir in 2011 and is operated from New York, United States.
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Khosla Ventures
VC Fund · Menlo Park, California, United States · 9 investments in United States Life Science startups

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Series B, Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1253
  • Round size: Seed $2M–$27M; Series A $5.7M–$47M; Series B $10M–$100M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely still investing — raised $557M in 2022

Portfolio highlights

  • Vectra AI — Vectra AI, the cybersecurity AI company that protects modern networks from modern attacks.
  • Zebra Medical Vision — NANOX AI enables more accurate risk-adjustment so patients are provided with preventative care paths they need, while improving quality of health services at significantly lower associated costs.
  • Blue River Technology — Blue River Technology is a pioneer in the use of computer vision and robotics for agriculture. Founded in 2011 by two Stanford University Alumni, Blue River Technology is bringing crop protection into the digital era with See & Spray machines that precisely observe and treat each plant in a field. By applying herbicides only to weeds thesemachines dramatically reduce the amount of chemicals used, enable farmers the freedom to choose any herbicide that meets their needs, and improve grower economics. Currently, farmers are limited to equipment that applies fertilizer and chemicals inefficiently across an entire field. In contrast, Blue River have developed tractor-towed robots that are able to sense each individual plant and precisely apply the right amount of inputs – all in real time, at tractor speeds.
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Horizons Ventures
VC Fund · Hong Kong, Hong Kong Island, Hong Kong · 9 investments in United States Life Science startups

Investing in the deep science and technology that can propel humanity towards a radically better future.

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Investment focus

  • Industry: Biotechnology, Software, Artificial Intelligence
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 274
  • Round size: Seed $1M–$11M; Series A $6.2M–$47M; Series B $10M–$110M
  • Lead/follow: 42% lead, 58% follow

Portfolio highlights

  • Onavo — Onavo, founded 2010, is the company behind Onavo Insights, the largest mobile intelligence service, and the developer of the award-winning Onavo mobile utility apps.Onavo Insights market intelligence data, powered by fully anonymized data from Onavo's apps, powers business decisions in companies in verticals diverse as finance, gaming,entertainment and social networking, and reports are cited regularly in the press as the primary barometer of the mobile app ecosystem.
  • Magisto — Magisto online video editor is a fast & powerful video maker. Turn your photos and video clips into video stories with Magisto movie editor. Start free!
  • Corephotonics — Corephotonics is the pioneer and worldwide market leader of dual camera technologies for smartphones and mobile devices, providing a perfect mobile camera photography experience, novel photography features and superior image quality
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Playground Global
VC Fund · Palo Alto, California, United States · 9 investments in United States Life Science startups

Playground Global is an early-stage venture capital firm backing technical and scientific founders with deep engineering expertise, a collaborative environment, and a first-hand understanding of the intricacies of deep tech. Established in 2015 and headquartered in Palo Alto, CA, Playground’s mission is to transform ambitious ideas into impactfulbusinesses that benefit humanity and the planet. We invest in areas that span across next gen compute automation, energy transition and engineered biology. Playground has been an early – and frequently first investor – in companies that include PsiQuantum, Relativity Space, Ultima Genomics, MosaicML (acq. by Databricks), d-Matrix, and Strand Therapeutics.

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Investment focus

  • Industry: Software, Robotics, Biotechnology
  • Stage:Series A, Series B, Seed
  • Geography: United States, Canada, Italy

Investor stats

  • Total investments: 142
  • Round size: Seed $2.2M–$20M; Series A $7M–$35M; Series B $23M–$150M
  • Lead/follow: 49% lead, 51% follow
  • Last fund: Likely still investing — raised $410M in 2023

Portfolio highlights

  • Photon Queue — Photon storage solutions.
  • Canvas Technology — CANVAS Technology is a robotics company with a mission to provide end-to-end autonomous delivery of goods. We’re creating safe and powerful autonomous technology that can power both indoor and outdoor driving.
  • Prazer Therapeutics — Prazer Therapeutics assists patients suffering from intractable diseases through the use of logical and innovative drug design approaches. They willaccomplished this through the use of new and innovative drug development platforms, such as rational molecular drug design technology and next-generation protein degradation technology.
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Versant Ventures
VC Fund · Menlo Park, California, United States · 9 investments in United States Life Science startups

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 296
  • Round size: Series A $5M–$72M; Series B $10M–$107M; Series C $12M–$108M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Graphite Bio — Graphite Bio is a next-generation gene editing company focused on therapies that harness targeted gene integration to treat or cure serious diseases
  • Dayra Therapeutics — Dayra Therapeutics manufactures peptide based medicines.
  • Jecure Therapeutics — Jecure Therapeutics is focused on the discovery of innovative therapeutics for the treatment of non-alcoholic steatohepatitis.
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Vivo Capital
VC Fund · Palo Alto, California, United States · 9 investments in United States Life Science startups

The firm is a 25-year-old global investment firm focused on healthcare with approximately $5.8 billion in AUM, which we have invested in over 290 public and private companies worldwide. Headquartered in Palo Alto, California, with offices in Asia. Our team consists of 50 multi-disciplinary professionals, including, physicians, scientists,entrepreneurs, operating executives, and industry experts. The firm operates as a multi-fund investment platform, covering growth equity, private equity including buyout, venture capital, and public equity. Vivo invests broadly in healthcare across all fund strategies, including biotechnology, pharmaceuticals, medical devices, and healthcare services, with a focus on the largest healthcare markets.

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Post-IPO Equity, Series B, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 250
  • Round size: Series B $28M–$125M; Series C $30M–$108M; Post-IPO Equity $40M–$180M
  • Lead/follow: 26% lead, 74% follow
  • Last fund: May invest from a new fund soon — raised $1.4B in 2019

Portfolio highlights

  • Provivi — Provivi is developing biopesticides for agriculture, commercial, household, and public health pest management. It has a world-class team of founders, scientists, and advisors with significant experience in biotechnology (including biocatalysis), the fine chemicals industry, and, in particular, the agchem industry. It pursues disruptiveopportunities enabled by breakthrough biological processes for making supply-limited products that are efficacious, safe, and environmentally benign.Provivi was founded in 2013 based on biocatalysis technology developed at the California Institute of Technology (Caltech) which has since become a licensor, shareholder, and research collaborator. It is based in Santa Monica, California.
  • Passage Bio — Passage Bio, a genetic medicines company, is changing the future of CNS disorders and transforming the lives of patients and their families.
  • BlossomHill Therapeutics — We are on a mission to exponentially improve the number of quality years for patients.
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Rev1 Ventures
VC Fund · Columbus, Ohio, United States · 9 investments in United States Life Science startups

Rev1 Ventures is a venture studio in Columbus, Ohio providing tech startups with services, space, mentoring, and connections. Learn more!

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A
  • Geography: United States, Germany

Investor stats

  • Total investments: 200
  • Round size: Seed $192k–$4M; Series A $1.2M–$18M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: May invest from a new fund soon — raised $20M in 2021

Portfolio highlights

  • FinOpsly — Maximize your cloud ROI with FinOpsly. Our AI-driven platform empowers organizations with smart cost management, fostering collaboration across teams for over 32% in savings. Simplify your cloud strategy with FinOpsly.
  • InnerActiv — InnerActiv is the leading NextGen eDLP solution, setting new standards in DLP, fraud and insider threat detection.
  • Niobium Microsystems — The encrypted cloud has arrived.
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iSelect Fund
VC Fund · St Louis, Missouri, United States · 8 investments in United States Life Science startups

Venture investing in Food, Health, and AgTech. A generational investment thesis. Food is Health is longevity

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Investment focus

  • Industry: Biotechnology, Health Care, Agriculture
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Australia

Investor stats

  • Total investments: 95
  • Round size: Seed $100k–$10M; Series A $3.3M–$41M; Series B $8.3M–$68M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: May invest from a new fund soon — raised $3.8M in 2019

Portfolio highlights

  • Miraterra — A New Era of Measurement: Unlocking the Secrets of Soil, Plants, and Food. Our breakthrough technology, overcoming decades of limitations, provides fast, efficient and trustworthy digital measurements when and where you need them most.
  • Mercy BioAnalytics — We are making early-stage cancer easier to find using extracellular vesicles found in blood, specific to their parent cells.
  • Vive Crop Protection — Vive Crop Protection makes effective and sustainable pesticides for organic and non-organic production. The company creates new ways to use proven crop protection products using their targeted Allosperse Delivery System, which improves the targeting and performance of pesticide active ingredients. This helps farmers do more with less, all whileincreasing crop quality and yields.Vive Crop Protection was founded in 2006 and is headquartered in Mississauga, Ontario, Canada.
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Life Science VC funding in United States at a glance

Stats across 3.4k deals from 3.3k investors.

3.3k
investors
in United States Life Science startups
3.4k
deals
in United States Life Science startups
$8.1M
median round
in United States Life Science startups
41%
lead investors
lead at least one round
18%
Seed
most common funding stage

Access all 3281 VC funds in United States Life Science startups.

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