Top 50 Life Science VC Funds & Investors in United States (September 2026)

Portfolio highlights

• Happy Health — Happy Ring is the most advanced biometric platform ever - capturing clinical grade, real-world data for research and enabling real-time.
• Synchron — The endovascular brain computer interface.
• Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.

Portfolio highlights

• Leal Therapeutics — Leal Therapeutics develops novel therapeutics for patients.
• Vedana Therapeutics — Vedana Therapeutics is a Seattle biotechnology company developing next-generation antibody therapies for migraine prevention.
• Khartis Therapeutics — Khartis is a drug discovery company developing oral therapies for patients with immune-mediated and chronic diseases. The company focuses on discovering and developing drug candidates intended to address chronic conditions and immune-mediated diseases.

Portfolio highlights

• LOLIWARE — LOLIWARE is rewriting the story of destructive packaging. By harnessing the power of seaweed to replace plastic at scale, LOLIWARE is tapping into its potential to regenerate our ocean and decarbonize our planet.
• Talk Local — Need a service professional? Search the Nation's #1 Service Directory. It's Free and Fast, get connected over the phone instantly with Local Plumbers, Accountants, Computer Repair Pros, Dentists, Heating & Cooling HVAC, and other service professionals!
• HopSkipDrive — Arranging safe, dependable transportation or children ages 6+ with qualified caregivers

Portfolio highlights

• E Ink — E Ink Corp. is a supplier of electronic paper display (EPD) technologies. Products made with E Ink's electronic ink are designed to possess a paper-like high contrast appearance, ultra-low power consumption, and a thin, light form. E Ink's technology is tailored for many consumer and industrial applications including handheld devices,watches, clocks, and public information and promotional signs.
• Songbird — DropCatch.com helps you secure expiring domain names.
• Kinaset Therapeutics — Kinaset Therapeutics is a therapeutics company that focuses on the advancement of novel drugs in areas of unmet medical needs. The company was founded in 2020 and is headquartered in Medfield, Massachusetts.

Portfolio highlights

• Saronic — Providing the most advanced and capable autonomous vessels in the maritime domain.
• Fieldguide — Fieldguide is a workflow automation and collaboration software platform for audit, attestation, assurance, and advisory practices and firms.
• Flywheel.io — Flywheel is a data management and analysis platform built specifically for scientists and the researcher's workflow. They empower research momentum by focusing on data and medical image capture, content management, scientific computation, and collaboration. With reproducible research in mind, they combine open-source methods from topuniversities, a modern web user interface, and an extensible compute engine based on containerization technology. The result is a software platform to accelerate discovery and help researchers do science, not IT.Flywheel accelerates new scientific discoveries in life-science, biotech, and academic imaging research through cloud-scale collaboration. As a result, imaging researchers are able to avoid innovation bottlenecks, and accelerate discovery by doing more science, and less IT.

Portfolio highlights

• Corvia Medical — Corvia Medical is a medical device company, focuses on developing structural heart devices for the treatment of heart failure. The company develops InterAtrial Shunt Device (IASD), a transcatheter device designed to treat diastolic heart failure (DHF), also known as heart failure with preserved ejection fraction (HFpEF). It was founded in 2009and headquartered in Andover, Massachusetts.
• NinePoint Medical — NinePoint Medical, Inc. is a transformational medical device company developing innovative, real-time, in vivo pathology devices. The company's first goal is to develop a device that enables remote pathology, or telepathology, which would facilitate immediate review of images during diagnostic procedures. This capability could potentiallyprovide physicians with immediately actionable information and eventually allow them to pursue therapeutic remedies at the time of diagnosis. This convergence of access, diagnosis and treatment during one procedure is expected to improve patient experiences and outcomes, improve the efficiency of care and provide important savings to the healthcare system. Headquartered in Cambridge, Mass., NinePoint is backed by Third Rock Ventures and Prospect Venture Partners.
• CytomX Therapeutics — CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies. Their mission, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases.

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• Faro AI — The AI Platform for Clinical Development
• Culture Biosciences — Culture Biosciences provides a platform of cloud-connected bioreactors, software tools, and process development services that support upstream bioprocess development for biotech and biopharma applications. The company’s offerings include remote experiment design, monitoring, and data analysis through an integrated cloud software interface pairedwith single-use bioreactors for microbial fermentation and cell culture experimentation. Its services encompass clone and strain screening, process optimization, characterization, and bioprocess modeling to help scientific teams refine and scale their workflows. Clients access real-time data and analytics to inform decisions and collaborate across teams using the platform’s tools. Culture Biosciences’s technology is used to advance development of therapeutics, synthetic biology products, and related bioprocesses. Culture Biosciences was founded in 2016 and is headquartered in San Francisco, California.
• EnPlusOne Biosciences — EnPlusOne Biosciences provides innovative solutions for emerging RNA therapeutics.

Portfolio highlights

• Windward Bio — Windward Bio is a clinical-stage, drug development company committed to improving outcomes for people living with serious immunological diseases.
• Acceleron Pharma — At Merck, we're following the science to tackle some of the world's greatest health threats. Get a glimpse of how we work to improve lives.
• Insilico Medicine — Artificial Intelligence for Drug Discovery and Aging Research

Portfolio highlights

• Epirus — Epirus is a high-growth technology company that develops cutting-edge directed energy systems and power management solutions to transform multiple industries.
• BQP — At BQP, we’re developing a quantum-accelerated digital twin platform for mission-critical applications. The platform, BQPhy, is a back-end engine that integrates seamlessly into existing engineering workflows and operates on today’s infrastructure without requiring quantum hardware. BQPhy helps teams solve large-scale, complex challenges inengineering optimization, data-driven modeling (ML), and physics-based (CFD) simulations. We are bridging the gap between current high-performance computers and future quantum systems with probabilistic algorithms from quantum information science, unlocking simulation capabilities that were previously impractical or impossible. BQPhy reduces time, accuracy, and throughput inefficiencies, thereby accelerating development cycles, unlocking previously unexplored design spaces, lowering costs, and enhancing product outcomes.
• Sharper Sense — Neuromodulation for Clear Senses

Portfolio highlights

• Gusto — Gusto develops web-based payroll solution for small- and medium-sized businesses. It operates an online platform that provides payroll, benefits, human resources, and integration services for employers and employees in the United States.Gusto offers health benefits and workers’ compensation benefits that include medical insurance, commuterbenefits, and 401(k) contributions as well as workers’ compensation insurance plans, time tracking, and integration services, and access to employees for processing payroll from web-enabled devices such as smartphones and tablets. It also provides access to employees and contractors to browse their previous pay stubs, review their payroll forms, verify their personal details, and statistics about their pay, tax payments and federal forms filing services, and security and support services.Gusto serves startups, coffee shops, doctors, creative agencies, lawyers, and boutiques. Edward Kim, Joshua Reeves, and Tomer London founded ZenPayRoll in 2011 that became Gusto, with its headquarters in San Francisco in California with an additional office in Denver in Colorado.
• Wonder — Introducing a new kind of home dining experience. Currently available in areas of New Jersey.
• OpenEvidence — OpenEvidence uses artificial intelligence to aggregate, synthesize, and visualize clinical evidence in understandable, clinically-useful formats that can be used to make more evidenced-based decisions and improve patient outcomes.

Portfolio highlights

• Waymo — Waymo stands for a new way forward in mobility. it is a self-driving technology company with a mission to make it safe and easy for people and things to move around.Waymo improves transportation by building software and sensor technology developed in Google’s labs since 2009. In October 2015, they achieved the world’s first fully self-drivingtrip on public roads, in a car without a steering wheel or pedals. They refine Waymo technology through one billion miles of simulation testing each year, and the cars have self-driven over two million miles on public roads across four U.S. cities.It was founded in 2009 and is located in Mountain View, California.
• GoodData.AI — GoodData is a leading composable data and analytics platform. Build, embed, and scale analytics on demand, with zero vendor lock-in.
• Apex — Apex manufactures ESPA-class satellites, ranging from 40 to 400kg. Our first spacecraft bus platform, Aries, is built for LEO missions for earth observation, communications, and more. Configure the Aries bus to meet your specific mission profile.

Portfolio highlights

• Albedo — Aerial quality imagery - from space.
• Eden — Eden unifies medical imaging operations with clinical AI: PACS, teleradiology, AI-assisted diagnosis and structured reporting, deployed across 2,600+ imaging departments.
• Attention — Attention is building an AI co-pilot designed to automate repetitive, multi-app desktop tasks.

Portfolio highlights

• Serapha Bio —
• Windward Bio — Windward Bio is a clinical-stage, drug development company committed to improving outcomes for people living with serious immunological diseases.
• Kinaset Therapeutics — Kinaset Therapeutics is a therapeutics company that focuses on the advancement of novel drugs in areas of unmet medical needs. The company was founded in 2020 and is headquartered in Medfield, Massachusetts.

Portfolio highlights

• CH4 Global — CH4 Global is an aquaculture solutions provider dedicated to urgently impacting climate change at scale. Lead by a world-class team of senior business builders, scientists and entrepreneurs, the company is initially leveraging proven science and technology for growing seaweed into innovative new livestock supplement that reduces methane produced bycows by up to 90%. Among early investors are a select group of prominent family offices and private investors. CH4 Global have also received non-dilutive capital support from government organizations from around the world. CH4 Global is a Delaware corporation based in Henderson, NV.
• Regent — We build all-electric, passenger-carrying, wing-in-ground-effect vehicles to service coastal routes with technology available today.
• Callosum — Callosum - Co-evolving chips & intelligence

Portfolio highlights

• Visiogen — Visiogen, Inc. is an ophthalmic medical device company specializing in the development of new vision alternatives for patients with cataracts, with and without presbyopia. As part of this mission, Visiogen created the Synchrony dual optic accommodating *intraocular lens (IOL)* for use in the surgical treatment of these conditions.The device isdesigned to provide patients with near, intermediate and distance vision in a seamless continuum without the need for glasses or contact lenses. To eliminate lens handling during surgery, the Synchrony dual optic IOL is provided in a pre-loaded injector. This patented technology has been approved in Europe with a CE Mark designation and is currently undergoing clinical trials in the United States.
• Protego Biopharma — Protego Biopharma develops therapeutics based on the clear human genetic link, excellent human safety profile, proof-of-principle efficacy. The company was founded in 2011 and is headquartered in San Diego, California.
• Rein Therapeutics — Rein Therapeutics is advancing a novel pipeline of first-in-class medicines to address unmet medical needs in orphan pulmonary and fibrosis indications.

Portfolio highlights

• Gridware — Using remote telemetry and edge AI, Gridware wildfire prevention technology powers a grid that is smarter and more reliable than ever before.
• Onepot.ai — Search 2.7 billion make-on-demand analogs from onepot CORE, get a quote, and we synthesize and QC them in our US-based lab. AI-powered custom synthesis.
• Adaption Labs — Adaptation creates AI systems that adjust to changing real-world circumstances.

Portfolio highlights

• Midi Health — Expert care for women 40+. Made for midlife. Delivered by experienced clinicians. Covered by insurance. Book a visit today.
• Petasense — Founded with a vision of making industrial machines smarter, Petasense is an Industrial IoT startup based in Silicon Valley. The company offers an end-to-end solution – comprised of a patent-pending wireless vibration sensor, cloud software and machine learning analytics – that helps with asset reliability and predictive maintenance. Customersare able to monitor, assess and predict the health of their critical machines in real-time. This helps them reduce unplanned downtime and lower repair costs. Petasense's clients include industry leaders like JLL, C&W Services, Silicon Valley Power and Stanford University. Petasense is backed by True Ventures, Felicis Ventures and top angel investors. The company is founded by serial entrepreneurs, Abhinav Khushraj and Arun Santhebennur, who have 25 years of combined experience in building enterprise companies, with degrees from MIT and IIT.To learn more about Petasense, visit www.petasense.com.
• ConductorOne — Govern workforce access, deploy AI agents, and get work done with C1.

Portfolio highlights

• Zag Bio — Zag Bio is harnessing the immune system in a whole new way by targeting the thymus to change treatment possibilities for millions of patients with autoimmune diseases.
• Skeletalis — Skeletalis is a biotechnology startup focused on developing next-generation precision medicines for musculoskeletal diseases, primarily osteoporosis.
• Tacit Therapeutics — New broadly-applicable and non-immunogenic RNA gene therapy that can treat thousands of devastating illnesses.

Portfolio highlights

• iOrganBio — The Right Cells. Consistently. At Scale.
• Galatea Bio — Galatea Bio, a US-based biotechnology company was founder by Carlos Bustamante, Nicholas Katsanis and Alexander Ioannidis. Our mission is to drive groundbreaking discoveries in healthcare by pairing genetic diversity with cutting-edge data analytics. Our passion is fueled by a focus on populations historically underrepresented in genetics research.We achieve this by leveraging our world-class clinical network and biobank, cutting-edge algorithms, and innovative analyses to discover and validate new tests, treatments, and cures that will improve the lives of all.
• Italic Health — Italic Health, Inc. is a healthcare technology company building a unified platform for managing patient data, medical billing, and insurance workflows. Its software integrates health records, appointment scheduling, and AI-driven analytics to improve care coordination, financial processes, and patient engagement.

Portfolio highlights

• Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.
• Khartis Therapeutics — Khartis is a drug discovery company developing oral therapies for patients with immune-mediated and chronic diseases. The company focuses on discovering and developing drug candidates intended to address chronic conditions and immune-mediated diseases.
• Aeovian Pharmaceuticals — Aeovian is a San Francisco based biopharmaceutical company developing novel and highly selective therapeutics modulating mTORC1 pathway.

Portfolio highlights

• ZoomInfo — ZoomInfo provides access to more direct dials and email addresses than any other B2B contact provider. Verified professional and business profiles come fully loaded with detailed information about prospects, including web mentions, employment history, and direct access to colleagues, people can engage ideal buyer personas and accounts in a moremeaningful way. ZoomInfo uses its diverse portfolio of proprietary technology, a community of 300,000+ users, and third-party integrations to collect, organize, validate, and publish a comprehensive directory of business data in the marketplace.ZoomInfo's mission is to provide every company with a 360-degree view of their ideal customer, empowering each phase of their go-to-market strategy, and driving their ability to hit their number. ZoomInfo was founded in 2000 and is headquartered in Waltham, Massachusetts.
• Foghorn Therapeutics — Foghorn Therapeutics is developing therapies based on a system that directs which genes our cells express, and when, where, and in what order.By manipulating this system with our unique Gene Traffic ControlTM platform, Foghorn will change how genes turn “on” and “off.” Unlike approaches that edit genes, this novel way of thinking will alter whatour DNA has in store for us—and rewrite destiny for millions of people living with disease.With Gene Traffic ControlTM Foghorn is pioneering a new, major class of drug targets to develop unprecedented therapies for cancer and other serious diseases. We have already validated multiple targets, are in the process of developing drug candidates in multiple types of cancer and are beginning to explore other diseases.
• Serif Bio­med­i­cines — Serif Biomedicines is pioneering Modified DNA as a new type of biotechnology. Serif combines nucleic acid chemistry, synthetic biology, delivery technology, and artificial intelligence to develop programmable, scalable, long-lasting, and redosable DNA therapies.

Portfolio highlights

• Ascidian Therapeutics — Ascidian Therapeutics is a biotechnology company intended for medical use in medical and clinical gene therapy.
• Red Queen Therapeutics — Staying ahead of viral threats with new innovations in antiviral therapy
• Deep Apple Therapeutics — Deep Apple Therapeutics is discovering new small-molecule therapeutics with unprecedented speed and exceptional acumen.

Portfolio highlights

• Vals.ai — Private, domain-specific benchmarks in legal, tax, and finance.
• Infinimmune — Derived from human biology, engineered for human health. Infinimmune systematically surfaces and engineers the rare antibodies evolution has already proven in people and advances them into the clinic.
• Maximum — Maximum is a boutique agency that likes to remain small and agile. There are sixty of us, all specialists, and our advanced digital solutions are 100% generated in-house. We have a knowledgeable and sophisticated research presence, especially in the digital arena and with regard to social recruitment. This means we can make things happen for youthat other agencies can't. Giving your organization the edge takes serious research, heavyweight strategy, considered creativity and intelligent use of the digital space. This is why we've developed the Social Recruitment Monitor™ for you, the definitive index on the use of social media for recruitment purposes.

Portfolio highlights

• Vectra AI — Vectra AI, the cybersecurity AI company that protects modern networks from modern attacks.
• LanzaTech — LanzaTech is turning our global carbon crisis into a feedstock opportunity with the potential to displace 30% of crude oil use today and reduce global CO2 emissions by 10%. By recycling carbon from industrial off-gases; syngas generated from any biomass resource (e.g. municipal solid waste (MSW), organic industrial waste, agricultural waste); andreformed biogas, LanzaTech can reduce emissions and make new products for a circular carbon economy.LanzaTech’s carbon recycling technology is like retrofitting a brewery onto an emission source like a steel mill or a landfill site, but instead of using sugars and yeast to make beer, pollution is converted by bacteria to fuels and chemicals! Imagine a day when your plane is powered by recycled GHG emissions, when your yoga pants started life as pollution from a steel mill. This future is possible using LanzaTech technology.
• littleBits Electronics — LittleBits is an open source library of over 60 electronic modules that snap together with magnets allows users to view, download, and share designs and make their own Bits through the use of prototypes. Deluxe kit, Smart home kit, Arduino coding kit, Synth kit, hardware development kit, and workshop set are some of the electronics learning modulesprovided by littleBits.LittleBits was launched by Ayah Bdeir in 2011 and is operated from New York, United States.

Portfolio highlights

• Nura Bio — Nura Bio revolutionizes the treatment of neurological diseases with novel, life-changing neuroprotective medicines. Nura Bio was conceived in 2018 by The Column Group and its scientific founders.
• InduPro — InduPro is a biotechnology company that specializes in protein therapeutics and cell-surface platform technologies.
• Immune Design — Immune Design Corp. (IDC) uses breakthrough technology to develop safe and effective vaccines and therapeutics, with emphasis on the prevention and treatment of infectious disease. This goal is being achieved through dedicated research aimed towards a greater understanding of the immune system, and by developing a new generation of immune-basedproducts for the pharmaceutical industry. IDC is passionate about its mission to alleviate human suffering and pursues this goal with high energy and an unsurpassed standard of excellence

Portfolio highlights

• Adimab — Premier Human Antibody Discovery and Optimization
• Toonimo — Toonimo humanize the web user experience with an engaging and personalized step-by-step interactive walkthrough
• Cajal Neuroscience — Cajal Neuroscience is a drug discovery company focused on neurodegenerative disease.

Portfolio highlights

• Orbem — Transform biological imaging with AI-powered MRI technology. Non-invasive solutions for poultry, fruits, nuts, and health. Building a sustainable future.
• Empathy — Coping with the loss of a loved one is not easy. Download the Empathy App for guidance on what to expect following a loss and the tools to get you through each step.
• Kouper Health — The transitions-of-care platform ensuring patients receive timely access to follow-up care.

Portfolio highlights

• OxCan — Enabling curative cancer treatment through early detection
• 10x Science — AI-native software to unlock drug development.
• Rinascera Therapeutics — Rinascera Therapeutics develops transformative therapies for rare genetic skin diseases, including RIN-001 for Gorlin Syndrome and RIN-002 for Dystrophic Epidermolysis Bullosa (DEB).

Portfolio highlights

• Ousia Pharma — Ousia Pharma is paving the way for novel therapeutic strategies using peptide-drug-conjugates
• Windward Bio — Windward Bio is a clinical-stage, drug development company committed to improving outcomes for people living with serious immunological diseases.
• Protego Biopharma — Protego Biopharma develops therapeutics based on the clear human genetic link, excellent human safety profile, proof-of-principle efficacy. The company was founded in 2011 and is headquartered in San Diego, California.

Portfolio highlights

• Orna Therapeutics — Orna Therapeutics is a biotechnology company dedicated to designing and delivering a new class of fully engineered circular RNA (oRNA) therapeutics with the potential to change the way we treat disease. Orna’s proprietary platform combines novel technology to create oRNAs that drive protein expression with validated and unique delivery solutions.
• Aratana Therapeutics — Aratana is uniquely positioned to deliver new, high-quality medicines to address unmet needs in companion animal care. We are committed to bringing world class science to animal health for companion animals and the people who care for them. Our competitive advantage resides in our ability to identify, acquire and develop high-value commercialproducts for companion animals in a cost effective and efficient manner.
• Rhythm Pharmaceuticals — Rhythm Pharmaceuticals is a global biopharmaceutical company committed to transforming the lives of patients with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause.

Portfolio highlights

• Epicrispr Biotechnologies — The Gene Expression Modulation System (GEMS) technology from Epic-Bio combines a DNA-binding protein, a tailored guide RNA, and any of a wide range of modulator proteins to generate a powerful new type of genetic medicine. GEMS medicines have the ability to precisely modify gene expression both in and out of the body. They are mutation-independent,which means that a single GEMS design can address the majority or all genetic subtypes of a disease.
• Processa Pharmaceuticals — Founded in Oct '17 with a mission to develop products that can improve the survival and/or quality of life for patients who have a high unmet medical need.
• Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.

Portfolio highlights

• microagi — Accelerating embodied AGI
• Legato Audio — Legato Hearing develops stylish glasses with built-in hearing technology, offering a discreet alternative to traditional hearing aids.
• Cast Insights — Cast Insights is an AI-powered platform that turns global spoken content—TV, radio, podcasts, livestreams—into structured, searchable real-time intelligence for investors, policy teams, strategists, and newsrooms.

Portfolio highlights

• EdgeX — Edokonta builds software that allows hospitals to track mobile equipment, such as IV pumps and ultrasounds. The company was founded in 2018 and based in San Diego, California.
• Nested Knowledge — Nested Knowledge is designing an interface that allows you to examine the data from a comprehensive literature review on research questions of interest. The interactive, nested features facilitate therapeutic comparisons, assist with research organization, and allow physicians to compare nuances across patient characteristics and outcomes.
• Major Medical Devices — Major Medical Devices develops next-generation vascular devices for endovascular repair and related surgical procedures.

Portfolio highlights

• Swarm Aero — Swarm empowers small teams to mobilize thousands of uncrewed vehicles in communications-limited, contested environments.
• Artemis — Artemis is the first protective layer that is AI-native
• littleBits Electronics — LittleBits is an open source library of over 60 electronic modules that snap together with magnets allows users to view, download, and share designs and make their own Bits through the use of prototypes. Deluxe kit, Smart home kit, Arduino coding kit, Synth kit, hardware development kit, and workshop set are some of the electronics learning modulesprovided by littleBits.LittleBits was launched by Ayah Bdeir in 2011 and is operated from New York, United States.

Portfolio highlights

• OSPRI — OSPRI is updating the infectious illness testing plan. Established by the combination of Community Direct DX, Scienetix, and the R&D section of Advanta Genetics, OSPRI is among the first molecular testing platforms in the world to be entirely vertically integrated.
• Ratio Therapeutics — Ratio is a privately held discovery-stage biotechnology company that utilizes a suite of technologies licensed from Cornell University to develop best-in-class targeted radiotherapeutics for the treatment of metastatic cancers.
• Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.

Portfolio highlights

• tbh — tbh is a developer of a mobile application designed to provide anonymous feedback to friends. The company's mobile application facilitates asking or answering questions, open text fields and invite abuse when combined with anonymity, enabling users to say things without repercussions and feel better about themselves from the positive feedbackon social networks.
• Vidrovr — Vidrovr develops multimodal computer vision and machine learning systems to index, tag, and understand video. It processes videos with specific domain constraints, such as in sports, government, and media verticals. Its technology enables its users to search an indexed video corpus and retrieve content inside videos and link it to other media likephotos and text.The company Integrates social media to enable direct interactions between multimedia content. Vidrovr was founded in 2016 and is headquartered in New York.
• Experio AI — Turn contracts, proposals, and expertise into instant searchable intelligence. Win more, ramp faster, never lose knowledge. Enterprise AI for services.

Portfolio highlights

• SpineAlign Medical — SpineAlign Medical, Inc. designs and manufactures medical devices for spinal surgery. The company is based in San Jose, California.
• Viamet Pharmaceuticals — Viamet Pharmaceuticals discovers and develops "best-in-class" inhibitors of validated metalloenzymes via an innovative and proprietary metal-binding approach, their Metallophileâ„¢ Technology. Viamet's disruptive Metallophileâ„¢ technology is based on their world-class expertise in bioinorganic chemistry and metalloenzymes and allowsthem to identify validated targets with high therapeutic and commercial potential; leverage existing metalloenzyme inhibitors as the basis for Viamet's best-in-class analogs; and rapidly and cost-effectively generate best-in-class, patentable, small molecule compounds by optimizing the metal-binding component of existing inhibitors.
• TetraLogic Pharmaceuticals — TetraLogic Pharmaceuticals is a privately held biopharmaceutical company that discovers and develops small molecule drugs that modulate programmed cell death pathways to treat debilitating diseases and conditions. The company's Smac Mimetics neutralize critical blocks in the apoptosis pathway to selectively destroy cancer cells. ItsNecrostatin drugs block critical steps in the process leading to necrosis, enabling cell survival in a wide range of diseases and injuries where necrosis is a critical component of pathology.

Portfolio highlights

• Metriport — Metriport helps digital health companies access and manage patient health and medical data, through an open-source and universal API.
• Ozlo Sleep — Ozlo Sleep is a science-driven sleep and audio technology company that supports and simplifies sleep rituals for clinical benefits, without the use of medication.
• Stateless Networks — Performance, Visibility. Simplicity...It's time for a beautiful network. Stateless is transforming network operations for software-centric networking. Tying together deep network understanding with state-of-the-art distributed systems, cloud, data science and gaming expertise, Stateless transforms network visibility, performance andresponse and helps accelerate the transition to modern network platforms, tying together physical and virtual layers. Focused on the enterprise data center, Stateless currently partners with the world’s leading network and infrastructure vendors (including VMware (VMW), Cisco Systems (CSCO), Cumulus Networks and others) to deliver solutions to some of the world’s largest private data center operators. We’re looking for software and networking engineers in Greater Seattle and the Bay Area with expertise in one or more of the following areas: Distributed Systems, Service Oriented Architecture, Complex Event processing, Functional Programming, Virtualization, Network design and deployment, Network programming, Network troubleshooting, configuration and performance tuning and SDN. Bonus points for experience working with cloud infrastructure (AWS, Azure, OpenStack) or low-level systems software (linux kernel, hypervisors, compilers/language runtimes), complex gaming systems or graphics and computational geometry. For more information visit http://www.statelessnetworks.com/ or follow Stateless on Twitter: @statelessntwrks.see

Portfolio highlights

• Synthesize Bio — Deep biomedical data is the key to unlocking discoveries and creating therapies. Synthesize Bio uses AI to reduce data collection and analysis from months to minutes for a fraction of the cost in time, personnel, and materials.
• Archon Biosciences — Archon is a biotechnology firm that creates computationally engineered proteins to unleash potent therapeutic targets beyond the grasp of current methods and improve disease management.
• ZymeCO — ZymeCO is a bio-manufacturing company that develops enzyme-based biological products designed for sustainable agriculture and turf management. The company utilizes a bio-process that transforms organic matter to build soil health, accelerate residue decomposition, and boost plant growth.

Portfolio highlights

• CalciMedica — CalciMedica was founded in December 2006 by Gonul Velicelebi, Ph.D., Kenneth Stauderman, Ph.D. and Jack Roos, Ph.D., all previously with TorreyPines Therapeutics, where they discovered the role of STIM1 in the Icrac pathway in 2003. Other co-founders, all from the CBR Institute, include Anjana Rao, Ph.D., Patrick Hogan, Ph.D. and Stefan Feske, M.D,who identified Orai1 as the CRAC channel subunit in 2006.
• Windward Bio — Windward Bio is a clinical-stage, drug development company committed to improving outcomes for people living with serious immunological diseases.
• CHARM Therapeutics — CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins.

Portfolio highlights

• Infinimmune — Derived from human biology, engineered for human health. Infinimmune systematically surfaces and engineers the rare antibodies evolution has already proven in people and advances them into the clinic.
• Photon Queue — Photon storage solutions.
• Prazer Therapeutics — Prazer Therapeutics assists patients suffering from intractable diseases through the use of logical and innovative drug design approaches. They willaccomplished this through the use of new and innovative drug development platforms, such as rational molecular drug design technology and next-generation protein degradation technology.

Portfolio highlights

• ReadMe — Make your APIs easy to use and your developers successful.
• Lemon Cash — Lemon Cash is digital wallet with FIAT and crypto capabilities. End to end digital ecosystem for Latin America.
• Mersana Therapeutics — Discover how Day One is disrupting the status quo of traditional drug development to bring new medicines to children and adults with cancer.

Portfolio highlights

• Neion Bio — We convert nature's best molecular factories into the biomanufacturing platform of the future.
• Omni — Omni provides Healthy Vegan Dog Food in the UK, made by vets to be a nutritionally complete meal for your dog. Feed your dog all the goodness of plants backed by science.
• Buddy Bites — Subscription pet food delivered straight to your door! Convenient & healthy pet food approved by vets. Made in Europe with premium quality. 2kg to you, 1kg donated to Hong Kong pet shelters.

Portfolio highlights

• eBrevia — Analyze contracts at scale, extract key data, and identify risk with eBrevia. Draft and redline agreements in Microsoft Word with DraftPro.
• Mobile Sense — The traditional diagnostic market is being transformed by advances in high performance wearables. This seismic shift led by consumer products which are uncovering new patients who previously went undetected, but still require a detailed diagnosis. Mobile Sense™ is building foundational technology that enables this transformation throughoff-the-chest wearables for long term management of cardiac arrhythmias. Developed over 7 years with $4.2M in grant funding and $1.3M in seed funding, Mobile Sense™ has a platform for differentiated wearables. Our embedded algorithms coupled with non-adhesive, wireless & waterproof sensors provides high fidelity continuous ECG and PPG recordings. The automatic monitoring provides 24/7, 365 days/yr continuous detection and classification of dangerous heart arrhythmias.
• NovaTract Surgical — NovaTract Surgical is a development stage company, intends to develop medical devices to address the rapidly growing field of Single Incision Laparoscopic Surgery (SILS) and Natural Orifice Transluminal Endoscopic Surgery (NOTES). The company was incorporated in 2010 and is based in Guilford, Connecticut.

Portfolio highlights

• Q32 Bio — Q32 Bio is developing drugs targeting powerful regulators of both the innate and adaptive immune systems with the goal of re-balancing the immune system.
• Contraline — Contraline is a medical device company that has developed a proprietary injectable hydrogel platform for use in reproductive and contraceptive applications. Contraline's first product, Adam, is implanted into the vas deferens through a minimally invasive, outpatient procedure and once implanted, the gel effectively blocks sperm. Adam isnon-hormonal, designed to last years, and easily reversible.
• Entera Bio — Entera Bio is developing novel oral drugs by utilizing its proprietary cutting edge delivery technology This technology protects large molecules and peptides in the GI tract. Oral drug delivery is the most straight forward and user friendly approach to medical treatment. Entera Bio has key personnel with the relevant know how, experience andnetworks working together to enable rapid development of its products. The company has an experienced management team with more than 50 years of combined drug development experience.

Portfolio highlights

• Penny Finance — Get a tailored financial & investing plans, track your money making, learn about personal finances & get new insights, all in the Penny Finance investing app for women.
• Yuva Biosciences — Using cutting edge mitochondrial science to develop cosmeceuticals and pharmaceuticals.
• Cayuga Biotech — Cayuga Biotech is a startup developing novel hemostatic drugs and devices to reduce uncontrollable bleeding which is a leading cause of death from traumatic injuries. The company's polyphosphate-based drug accelerates the body's own clotting process to contain clotting at the injury site and thus minimize the risk of side effects. Cayugais developing drugs for indications that treat traumatic hemorrhage as well as rare bleeding disorders.

Portfolio highlights

• AAVantgarde Bio — AAVantgarde is a clinical-stage biotechnology company developing next-generation therapies for inherited retinal diseases with high unmet need
• Coultreon Biopharma — Coultreon Biopharma is a clinical-stage biotech company developing next-generation precision medicines for immunology and autoimmune disease. Our pipeline targets SIK3 to deliver transformative therapies where unmet need remains high.
• Khartis Therapeutics — Khartis is a drug discovery company developing oral therapies for patients with immune-mediated and chronic diseases. The company focuses on discovering and developing drug candidates intended to address chronic conditions and immune-mediated diseases.

Portfolio highlights

• Docker — Docker is a platform designed to help developers build, share, and run container applications. We handle the tedious setup, so you can focus on the code.
• Opendoor Technologies — Opendoor is the new way to sell your home. Skip the hassle of listing, showings and months of stress, and close on your own timeline. Get a free offer today!
• Hyperpublic — Hyperpublic is an open database of people, places, and things tied to a specific location. Anyone can add objects to the database and developers will be able to build applications on top of the data.

Portfolio highlights

• Entera Bio — Entera Bio is developing novel oral drugs by utilizing its proprietary cutting edge delivery technology This technology protects large molecules and peptides in the GI tract. Oral drug delivery is the most straight forward and user friendly approach to medical treatment. Entera Bio has key personnel with the relevant know how, experience andnetworks working together to enable rapid development of its products. The company has an experienced management team with more than 50 years of combined drug development experience.
• Expedition Therapeutics — Redefining Care. Advancing COPD and Other Respiratory Therapies. Expedition Therapeutics is developing novel treatments for inflammatory and respiratory diseases with the potential to fundamentally transform patient care worldwide. ABOUT US At Expedition Therapeutics, we believe that disease-controlling treatments that address fundamental disease mechanisms should be the new standard for chronic obstructive pulmonary disease (COPD). Our
• BlossomHill Therapeutics — We are on a mission to exponentially improve the number of quality years for patients.