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Top 50 Life Science VC Funds & Investors in United States (June 2026)

The most active venture capital funds investing in United States Life Science startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in United States Life Science startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
ARCH Venture Partners
VC Fund
25 United States, China, United Kingdom Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $7.8M–$250M
Alexandria Venture Investments
VC Fund
22 United States, Canada, France Series A, Series B, Seed Biotechnology, Health Care, Therapeutics $2M–$150M
SOSV
VC Fund
21 United States, India, United Kingdom Seed, Convertible Note, Pre-Seed Biotechnology, Health Care, Software
Northpond Ventures
VC Fund
20 United States, United Kingdom, Canada Series A, Series B, Series C Biotechnology, Health Care, Life Science $10M–$100M
RA Capital Management
VC Fund
16 United States, United Kingdom, Canada Series B, Series C, Post-IPO Equity Biotechnology, Health Care, Therapeutics $26M–$235M
Atlas Venture
VC Fund
15 United States, United Kingdom, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $3.2M–$115M
Third Rock Ventures
VC Fund
15 United States Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $11M–$150M
DCVC
VC Fund
14 United States, Canada, United Kingdom Seed, Series A, Series B Software, Artificial Intelligence, Machine Learning $1.5M–$130M
Novartis Venture Fund
VC Fund
14 United States, Switzerland, United Kingdom Series B, Series A, Series C Biotechnology, Health Care, Therapeutics $5.1M–$120M
Andreessen Horowitz
VC Fund
13 United States, United Kingdom, Brazil Series A, Seed, Series B Software, Information Technology, Artificial Intelligence $1.5M–$107M
Alix Ventures
VC Fund
13 United States Seed, Series A, Pre-Seed Health Care, Biotechnology, Life Science $2M–$70M
OrbiMed
VC Fund
13 United States, China, Israel Series B, Series A, Series C Biotechnology, Health Care, Medical $10M–$150M
8VC
VC Fund
12 United States, United Kingdom, Canada Series A, Seed, Series B Software, Health Care, Artificial Intelligence $2.7M–$175M
Civilization Ventures
VC Fund
12 United States, United Kingdom, Brazil Seed, Series A, Series B Biotechnology, Health Care, Medical $1.7M–$144M
Google Ventures
VC Fund
12 United States, United Kingdom, Israel Series A, Series B, Seed Software, Health Care, Biotechnology $1M–$107M
Fifty Years
VC Fund
11 United States, Germany, Canada Seed, Series A, Series B Biotechnology, Health Care, Artificial Intelligence $2M–$91M
General Catalyst
VC Fund
11 United States, United Kingdom, India Series A, Seed, Series B Software, Artificial Intelligence, Health Care $1.6M–$135M
Hatteras Venture Partners
VC Fund
11 United States, Canada Series A, Series B, Series C Health Care, Biotechnology, Medical $5M–$90M
Artis Ventures
VC Fund
11 United States, United Kingdom, India Series A, Series B, Seed Health Care, Biotechnology, Software $2M–$127M
Sahsen Ventures
VC Fund
10 United States, China, Ghana Seed, Series A Biotechnology, Health Care, Non Profit $1.2M–$81M
KdT Ventures
VC Fund
10 United States, India, Canada Seed, Series A, Series B Biotechnology, Health Care, Medical $2.6M–$175M
MPM Capital
VC Fund
10 United States, Canada, United Kingdom Series B, Series A, Series C Biotechnology, Health Care, Pharmaceutical $9M–$125M
SR One
VC Fund
10 United States, United Kingdom, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $3.7M–$150M
Flagship Pioneering
VC Fund
10 United States, Canada, United Kingdom Series B, Series C, Series A Biotechnology, Health Care, Medical $5.5M–$140M
Omega Funds
VC Fund
10 United States, Switzerland, United Kingdom Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $14M–$208M
Cormorant Asset Management
VC Fund
10 United States, China, Switzerland Series B, Series C, Series A Biotechnology, Health Care, Medical $16M–$200M
Alumni Ventures
VC Fund
9 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1.4M–$79M
Catalio Capital Management
VC Fund
9 United States, Switzerland, Israel Series A, Series B Biotechnology, Health Care, Life Science $18M–$150M
Rev1 Ventures
VC Fund
9 United States, Germany Seed, Series A Software, Health Care, Information Technology $192k–$18M
Lux Capital
VC Fund
9 United States, United Kingdom, Canada Series A, Seed, Series B Software, Artificial Intelligence, Health Care $1.8M–$150M
Versant Ventures
VC Fund
9 United States, Switzerland, Canada Series A, Series B, Series C Biotechnology, Health Care, Medical $4.7M–$108M
Pear VC
VC Fund
9 United States, Brazil, Colombia Seed, Series A, Pre-Seed Software, Artificial Intelligence, Health Care $500k–$35M
Longwood Fund
VC Fund
9 United States, United Kingdom, Italy Series A, Series B, Series C Biotechnology, Therapeutics, Health Care $16M–$152M
Gaingels
VC Fund
8 United States, Canada, Mexico Seed, Series A, Series B Software, Health Care, Artificial Intelligence $1.4M–$100M
Biotechnology Value Fund
VC Fund
8 United States, Switzerland, Canada Post-IPO Equity, Series B, Series A Biotechnology, Health Care, Therapeutics $6.1M–$176M
Playground Global
VC Fund
8 United States, Canada, Italy Series A, Series B, Seed Software, Robotics, Biotechnology $2.2M–$153M
5AM Ventures
VC Fund
8 United States, Switzerland, United Kingdom Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $13M–$110M
The Column Group
VC Fund
8 United States Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $9.2M–$120M
Apple Tree Partners
VC Fund
8 United States, Canada, United Kingdom Series A, Series B, Seed Biotechnology, Health Care, Therapeutics $3.8M–$90M
New Enterprise Associates
VC Fund
8 United States, India, United Kingdom Series A, Series B, Series C Software, Health Care, Biotechnology $5.3M–$103M
Digitalis Ventures
VC Fund
8 United States, United Kingdom, China Series A, Seed, Series B Biotechnology, Health Care, Medical $1.5M–$132M
iSelect Fund
VC Fund
8 United States, Canada, Australia Seed, Series A, Series B Biotechnology, Health Care, Agriculture $100k–$59M
Khosla Ventures
VC Fund
8 United States, India, United Kingdom Series A, Series B, Seed Software, Artificial Intelligence, Health Care $2M–$100M
Vivo Capital
VC Fund
8 United States, China, United Kingdom Post-IPO Equity, Series B, Series C Biotechnology, Health Care, Pharmaceutical $28M–$177M
Oreilly AlphaTech Ventures
VC Fund
7 United States, United Kingdom, Canada Series A, Seed, Series B Software, E-Commerce, Internet $650k–$33M
F-Prime
VC Fund
7 United States, United Kingdom, China Series A, Series B, Series C Health Care, Biotechnology, Medical $9.2M–$130M
Vida Ventures
VC Fund
7 United States, China, India Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $35M–$260M
venBio Partners
VC Fund
7 United States, Canada, Switzerland Series A, Series B, Series C Biotechnology, Health Care, Pharmaceutical $20M–$259M
Connecticut Innovations
VC Fund
7 United States, Israel, Canada Seed, Series A Health Care, Biotechnology, Software $200k–$25M
Roche Venture Fund
VC Fund
7 United States, United Kingdom, Spain Series B, Series A, Series C Biotechnology, Health Care, Therapeutics
Access all 2688 VC funds in United States Life Science startups.

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822 industries, 177 countries. Updated daily. Emails and phones included.

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Investor list

ARCH Venture Partners
VC Fund · Chicago, Illinois, United States · 25 investments in United States Life Science startups

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 387
  • Round size: Series A $7.8M–$212M; Series B $13M–$250M; Series C $15M–$175M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • Ultivue — Ultivue is a biotechnology company that specializes in tissue imaging, diagnostics, and multiplexing. Ultivue produces reagents that enable researchers to obtain microscopic images at an unprecedented resolution that helps to understand of biology and medicine. Ultivue's products are designed for fluorescent microscopy-based research and willeventually be valuable for clinical diagnostic use. It was founded in 2015 and headquartered in Cambridge, Massachusetts.
  • EGenesis — At eGenesis, we envision a world where transplantation is accessible to all. We develop safe and effective human-compatible organs for transplantation.
  • Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
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Alexandria Venture Investments
VC Fund · Pasadena, California, United States · 22 investments in United States Life Science startups

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Seed
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 247
  • Round size: Seed $2M–$31M; Series A $12M–$100M; Series B $25M–$150M
  • Lead/follow: 7% lead, 93% follow

Portfolio highlights

  • miRecule — MiRecule is an early-stage biotechnology company that focuses on developing microRNA-based therapeutics. It features a genomic-based drug development platform that integrates genomic sequencing, expression, and prognostic data from cancer patients. The company was founded in 2016 and headquartered in Gaithersburg, United States.
  • Marvin Health — Marvin is a mental health service for physicians. We're ending the one-size-fits-all approach to teletherapy, helping you to set a teletherapy action plan.
  • Deep Genomics — Revolutions in AI, biology and automation are enabling a new approach to medicine. Deep Genomics is at the forefront.
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SOSV
VC Fund · Princeton, New Jersey, United States · 21 investments in United States Life Science startups, 75 in the past 12 months

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

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Investment focus

  • Industry: Biotechnology, Health Care, Software
  • Stage:Seed, Convertible Note, Pre-Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1482
  • Lead/follow: no public data

Portfolio highlights

  • MixRift — MIXRIFT - game developers specialized in Mixed Reality
  • unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
  • Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
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Northpond Ventures
VC Fund · Bethesda, Maryland, United States · 20 investments in United States Life Science startups

Northpond Ventures is a science-driven venture capital firm headquartered in Bethesda, Maryland. Our mission is to build a better tomorrow. Our investments are focused on life sciences, technology, and affiliated industries.

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Investment focus

  • Industry: Biotechnology, Health Care, Life Science
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 133
  • Round size: Series A $12M–$68M; Series B $10M–$100M; Series C $22M–$85M
  • Lead/follow: 62% lead, 38% follow

Portfolio highlights

  • Culture Biosciences — Culture Biosciences develops automated bio-reactor that helps biotech companies optimize their manufacturing processes and brings products to market faster. The company also builds automated tools for fermentation. It has a digital bio-manufacturing platform to enable scientists to run, monitor, and analyze bio-reactors faster than traditionalapproaches by robotic sample handling and cloud data monitoring and analysis.Culture Biosciences was founded in 2016 and is headquartered in San Francisco, California.
  • Scipher Medicine — At Scipher Medicine, we are committed to transforming the way providers prescribe drugs, as well as the way manufacturers, develop new drugs. We have built a molecular map of all protein interactions that identifies genomic signatures and links those to disease and predictive treatment outcomes. Using a simple blood sample to analyze RNA, we canpredict if a patient is likely to respond to a targeted therapy before therapy is prescribed. This insight allows patients to start the most effective therapy from day one. For our first commercial product, we have developed PrismRA®, a first-of-its-kind blood test that can predict which patients with rheumatoid arthritis are less likely to respond to TNFi therapies such as Humira® and Enbrel® so that such patients can go on alternative approved drugs.We also used a different one for the ACO Payer Summit, I’ve provided that as well: Scipher Medicine is building the future of patient treatment. Most patients who are prescribed blockbuster therapies today don't respond to treatment, costing the healthcare industry billions in wasted drugs while patients continue to suffer. Scipher's platform identifies which drug will work based on the patient's fundamental disease biology, and not based on symptoms, disease classification, or medical bias. A routine blood test predicts which drug he/she will respond to, with our first product focusing on rheumatoid arthritis, ensuring that the most optimal treatment is prescribed from day one. The molecular data generated by our tests is then used to fuel novel target discovery to address a clear unmet medical need in patients who do not respond to any existing therapy.
  • Sound Agriculture — Discover Sound Agriculture, an innovative agriculture company harnessing nature-based solutions that enhance resilience and sustainability.
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RA Capital Management
VC Fund · Boston, Massachusetts, United States · 16 investments in United States Life Science startups

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series B, Series C, Post-IPO Equity
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 448
  • Round size: Series B $26M–$152M; Series C $40M–$200M; Post-IPO Equity $34M–$235M
  • Lead/follow: 37% lead, 63% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • Curevo — focused on a new generation of adjuvanted subunit vaccines Learn More Our Focus We're dedicated to developing non-mRNA vaccines for unmet medical needs Curevo Vaccine is a clinical-stage biotech company dedicated to developing next-generation non-mRNA vaccines. We focus on one need at a time, allowing us to bring effective and better-tolerated vaccines to market quickly
  • ADCendo — ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs. We focus on antibody-drug conjugates (ADCs) directed at novel targets, that have been found to be overexpressed by several cancer forms, that are all characterized by a significant unmet need for novel treatment.
  • Terrestrial Bio — Vaxess engineers novel technologies that uniquely engage the human immune system, enabling improved efficacy and simplified access for vaccines and therapeutics.
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Atlas Venture
VC Fund · Cambridge, Massachusetts, United States · 15 investments in United States Life Science startups

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 418
  • Round size: Series A $3.2M–$75M; Series B $8M–$115M; Series C $6M–$95M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • Judo Bio — Judo Bio is pioneering oligonucleotide medicines delivered to the kidney, opening the way for new treatments for systemic and renal diseases.
  • Nimbus Therapeutics — Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company. Nimbus Therapeutics is a biotechnology company headquartered in Cambridge, Mass., that is pioneering a new computational technology-driven paradigm to rapidly advance a diverse pipeline of novel small molecule product candidates into clinicaldevelopment. We are designing highly selective and potent medicines to disrupt known drivers of serious diseases, including metabolic disease, cancer and immune-inflammatory disorders.
  • Remix Therapeutics — Remix Therapeutics is a biotechnology company that develops novel small molecule therapies designed to reprogram RNA processing and treat disease in entirely new ways.
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Third Rock Ventures
VC Fund · Boston, Massachusetts, United States · 15 investments in United States Life Science startups

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States

Investor stats

  • Total investments: 148
  • Round size: Series A $17M–$110M; Series B $11M–$150M; Series C $14M–$146M
  • Lead/follow: 45% lead, 55% follow
  • Last fund: Likely still investing — fund raised in 2022

Portfolio highlights

  • CytomX Therapeutics — CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies. Their mission, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases.
  • Rapport Therapeutics — Precision medicines to match the complexity of the human brain.
  • Synnovation Therapeutics — Synnovation Therapeutics is a precision oncology company focused on small molecule therapies optimized to target key driver mechanisms in cancers. It is dedicated to the discovery and development of therapeutics that can improve the lives of people with cancer. Leveraging its deep expertise in medicinal chemistry, cancer biology, andpatient-focused precision medicine, it builds a diverse pipeline of novel small-molecule targeted therapies. It aims to efficiently advance these agents into clinical trials with the goal of transforming cancer patient care.
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DCVC
VC Fund · San Francisco, California, United States · 14 investments in United States Life Science startups

We are deep tech venture capital.

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Investment focus

  • Industry: Software, Artificial Intelligence, Machine Learning
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 383
  • Round size: Seed $1.5M–$10M; Series A $5.7M–$45M; Series B $15M–$130M
  • Lead/follow: 24% lead, 76% follow
  • Last fund: Likely still investing — raised $1B in 2023

Portfolio highlights

  • ZwitterCo — ZwitterCo is revolutionizing water & wastewater treatment with cutting-edge membrane technology, along with providing sustainable, high-efficiency solutions.
  • Jupiter Intelligence — The Trusted Leader in Climate Risk Analytics. Learn about our best-in-science solutions.
  • Relation Therapeutics — Relation uses machine learning to develop drugs for pressing unmet need.
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Novartis Venture Fund
VC Fund · Basel, Basel-Stadt, Switzerland · 14 investments in United States Life Science startups

Learn about the approach the Novartis Venture Fund takes to investing in innovative life science companies developing biotechnology and biopharmaceutical therapeutics that address unmet patient needs.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series B, Series A, Series C
  • Geography: United States, Switzerland, United Kingdom

Investor stats

  • Total investments: 213
  • Round size: Series A $5.1M–$81M; Series B $11M–$120M; Series C $9M–$75M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: May invest from a new fund soon — raised $200M in 2009

Portfolio highlights

  • Splice Bio — Splice Bio is a gene therapy company based on technology developed in the Muir Lab at Princeton University. The company is developing novel gene therapies based on its proprietary intein platform technology to treat patients that suffer from incurable genetic diseases. The company’s platform has the potential to address two existing limitations ofadeno-associated viruses (AAVs), both by increasing the size of the cargo gene that can be delivered and by expanding the range of tissues that can be targeted.
  • Bionano Genomics — Discover how Bionano is striving to elevate health and wellness for all through optical genome mapping (OGM) solutions that transform the way the world sees the genome.
  • LOQUS23 THERAPEUTICS — LoQus23 is a DDF-formed company focussing on targeting DNA damage repair pathways to treat Huntington’s disease and other triplet repeat diseases.
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Andreessen Horowitz
VC Fund · Menlo Park, California, United States · 13 investments in United States Life Science startups

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

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Investment focus

  • Industry: Software, Information Technology, Artificial Intelligence
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Brazil

Investor stats

  • Total investments: 1630
  • Round size: Seed $1.5M–$15M; Series A $9M–$53M; Series B $16M–$107M
  • Lead/follow: 48% lead, 52% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • Glorify — Download Glorify - The Christian Daily Devotional & Wellbeing App. Structure your quiet time with Bible readings, guided meditations, reflections & prayers.
  • Databricks — Databricks offers a unified platform for data, analytics and AI. Build better AI with a data-centric approach. Simplify ETL, data warehousing, governance and AI on the Data Intelligence Platform.
  • Infinitus Systems — Infinitus Systems offers Voice Robotic Process Automation (VoiceRPA) software for businesses in the healthcare industry.
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Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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Alix Ventures
VC Fund · San Francisco, California, United States · 13 investments in United States Life Science startups

Supporting early stage Life Science startups driving patient impact. Born from our collective experience as founders, we set out to build the fund we wanted to raise from....

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Investment focus

  • Industry: Health Care, Biotechnology, Life Science
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States

Investor stats

  • Total investments: 23
  • Round size: Seed $2M–$12M; Pre-Seed $2.7M–$2.7M; Series A $12M–$70M
  • Lead/follow: 13% lead, 87% follow

Portfolio highlights

  • iOrganBio — iOrganBio is a pioneering cell production platform that uses CellForge to facilitate the intelligent manufacturing of human cells and organoids.
  • Galatea Bio — Galatea Bio, a US-based biotechnology company was founder by Carlos Bustamante, Nicholas Katsanis and Alexander Ioannidis. Our mission is to drive groundbreaking discoveries in healthcare by pairing genetic diversity with cutting-edge data analytics. Our passion is fueled by a focus on populations historically underrepresented in genetics research.We achieve this by leveraging our world-class clinical network and biobank, cutting-edge algorithms, and innovative analyses to discover and validate new tests, treatments, and cures that will improve the lives of all.
  • Italic Health — Italic Health, Inc. is a healthcare technology company building a unified platform for managing patient data, medical billing, and insurance workflows. Its software integrates health records, appointment scheduling, and AI-driven analytics to improve care coordination, financial processes, and patient engagement.
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OrbiMed
VC Fund · New York, New York, United States · 13 investments in United States Life Science startups

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, Israel

Investor stats

  • Total investments: 589
  • Round size: Series A $10M–$116M; Series B $24M–$150M; Series C $15M–$143M
  • Lead/follow: 35% lead, 65% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • Sonendo — Sonendo developing innovative technologies to transform dentistry by Saving Teeth Through Sound Science®. The GentleWave® System shows significant improvements in clinical efficacy and practice efficiency when compared to standard root canal treatment.1,2, 3 Sonendo is the parent company of TDO® Software, the developer of the most widely usedendodontic practice management software in the world, designed to simplify practice workflow. TDO software seamlessly integrates practice management, imaging, social media, referral reporting, CBCT imaging, and offers built-in communication with the GentleWave System.
  • Crown Bioscience — Crown Bioscience is an expert preclinical contract research organization providing oncology services and preclinical cancer models for drug development. Crown Biocience brings clarity to drug discovery worldwide, helping companies solve today's most pressing problems in immuno-oncology, oncology, cardiovascular, and metabolic diseases.
  • Aspen Neuroscience — personalized cell therapy Starts with you Learn More about our technology
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8VC
VC Fund · San Francisco, California, United States · 12 investments in United States Life Science startups

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies. The firm focuses on creating long-term economic and societal value through its investments across various sectors, including healthcare and logistics.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 481
  • Round size: Seed $2.7M–$13M; Series A $7.4M–$55M; Series B $16M–$175M
  • Lead/follow: 34% lead, 66% follow

Portfolio highlights

  • Raydiant — Raydiant empowers brick-and-mortar organizations to deliver engaging, personalized, and measurable on-screen digital experiences to delight in-store customers and engage back-of-house employees.
  • Adentro — Zenreach created Walk-Through Marketing to help businesses with physical locations dramatically improve customer acquisition and lifetime value by connecting digital marketing with in-store results. Zenreach Engage automatically tracks customer visits, effortlessly builds rich customer profiles and keeps them up to date. Zenreach Attract improvesad performance 4x by targeting audiences based on your best customers. Results are measured with our Walk-Through Rate™, a proprietary metric that shows when someone exposed to an ad visits a location. Founded in 2012, Zenreach serves thousands of independent merchants and leading brands like Peet’s Coffee, Ruth’s Chris and BCBG Max Azria.
  • Better Health — Better Health is a Modern Medical Supplier focused on delivering Urology & Ostomy Supplies. Shop the latest Catheters, Ostomy Bags from Hollister, Convatec, Coloplast and many more.
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Civilization Ventures
VC Fund · San Francisco, California, United States · 12 investments in United States Life Science startups

DIGITAL HEALTH / AI DIGITAL HEALTH / AI GENE / CELL THERAPIES NASDAQ: RCKT GENE / CELL THERAPIES NASDAQ: RCKT GENOMICS / DIAGNOSTICS GENOMICS / DIAGNOSTICS SYNTHETIC

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Brazil

Investor stats

  • Total investments: 73
  • Round size: Seed $1.7M–$16M; Series A $8.1M–$30M; Series B $26M–$144M
  • Lead/follow: 3% lead, 97% follow

Portfolio highlights

  • OxCan — Enabling curative cancer treatment through early detection
  • Wyndly — Retrain your allergies through sublingual (under-the-tongue) treatment plans. Virtual appointments. Treatment delivered. Get started after your first consult with a board-certified doctor for $49.99.
  • Foresight Diagnostics — We develop innovative diagnostics to advance decision-making in oncology drug development and patient care.
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Google Ventures
VC Fund · Mountain View, California, United States · 12 investments in United States Life Science startups

GV supports innovative founders moving the world forward.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 1029
  • Round size: Seed $1M–$15M; Series A $5.4M–$88M; Series B $15M–$107M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: May invest from a new fund soon — raised $100M in 2014

Portfolio highlights

  • Smarterer — Individuals and Fortune 500 companies use Smarterer to help close the gap between the skills they have and the skills they need. Their dynamic assessment engine leverages the freshest crowdsourced tests around, to rapidly pinpoint skill level with a credible score. In November 2014, Pluralsight, the global leader in online learning for serioussoftware developers, IT specialists and creative technologists, acquired Smarterer. As the world's largest curated e-learning library for professionals, the company offers instant access to more than 3,500 courses authored by top experts. Smarterer will continue to power crowdsourced assessments for freelancer marketplaces, e-learning providers and enterprise companies anywhere people need to prove their skills to connect with professional opportunities. The Smarterer community has answered over 56 million during 1.7 million test sessions, across hundreds of tests.
  • Zest — Give your shoppers the swiftest gifting experience in ecommerce. With Zest, shoppers on your site can send a gift to anybody, anywhere with just a link.
  • EpiBiologics — EpiBiologics develops first-in-class antibody based targeted therapies against membrane and extracellular proteins that drive underlying disease biology.
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Fifty Years
VC Fund · San Francisco, California, United States · 11 investments in United States Life Science startups

WE BACK HEROES using technology to solve the world's biggest problems

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Investment focus

  • Industry: Biotechnology, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Germany, Canada

Investor stats

  • Total investments: 162
  • Round size: Seed $2M–$15M; Series A $8.5M–$40M; Series B $16M–$91M
  • Lead/follow: 18% lead, 82% follow
  • Last fund: Likely still investing — raised $90M in 2021

Portfolio highlights

  • Farcast — Unlocking satellite internet capacity through user terminal innovation
  • Solugen — Solugen's mission is to decarbonize the chemicals industry. Solugen combines synthetic biology with metal catalysis to make carbon negative chemicals at scale.Solugen's patented approach takes advantage of bio-inspired reactions to use plant material as a low-cost feedstock to produce novel products cost-competitive with thecompetition.
  • Valence Discovery — Empowering drug discovery scientists with the latest advances in AI-enabled drug design
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General Catalyst
VC Fund · Cambridge, Massachusetts, United States · 11 investments in United States Life Science startups

Investing in powerful, positive change that endures

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 1591
  • Round size: Seed $1.6M–$18M; Series A $6M–$70M; Series B $12M–$135M
  • Lead/follow: 46% lead, 54% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • Ona — Your mission control for software projects & software engineering agents. Keep momentum on any device with sandboxed dev environments in our cloud or your VPC.
  • Orbem — Transform biological imaging with AI-powered MRI technology. Non-invasive solutions for poultry, fruits, nuts, and health. Building a sustainable future.
  • Bolna — Bolna offers voice AI agents that transforms business to qualify leads, boost sales, automate customer support, and streamline recruitment.
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Hatteras Venture Partners
VC Fund · Durham, North Carolina, United States · 11 investments in United States Life Science startups

Hatteras Venture Partners is a venture capital firm based in Research Triangle Park, NC, with a focus on biopharmaceuticals, medical devices, diagnostics, and related opportunities in human medicine. Founded in 2000, the firm consists of an experienced team with a broad and complementary skill set that is particularly relevant to buildingsuccessful new biomedical companies. The Hatteras Venture Partners team brings operational experience, a successful track record, and a proven ability to enhance the value of the companies in which it invests. With three funds, the firm has more than $120 million under management.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Canada

Investor stats

  • Total investments: 129
  • Round size: Series A $5.2M–$41M; Series B $5M–$90M; Series C $8M–$88M
  • Lead/follow: 37% lead, 63% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Ribometrix — The Next Frontier of Drug Discovery
  • Contego Medical — Better Outcomes. Simplified. Neurovascular Peripheral Vascular Neurovascular
  • G1 Therapeutics — G1 Therapeutics is a clinical-stage company developing novel cancer therapies. It was founded in 2008 by Drs. Norman Sharpless and Kwok-Kin Wong to capitalize on discoveries made and patented by Dr. Sharpless’ lab at the University of North Carolina at Chapel Hill, and subsequently licensed to G1 Therapeutics. Trilaciclib is an investigationaltherapy designed to improve outcomes for people with cancer who are treated with chemotherapy. G1 is also advancing rintodestrant, a potential best-in-class oral selective estrogen receptor degrader, or SERD, for the treatment of ER+ breast cancer.
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Artis Ventures
VC Fund · San Francisco, California, United States · 11 investments in United States Life Science startups

Artis Ventures has spent over a decade backing bold teams who take the hard path, building market-defining companies to re-shape, re-invent, and re-make industries.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 140
  • Round size: Seed $2M–$40M; Series A $4M–$55M; Series B $20M–$127M
  • Lead/follow: 38% lead, 62% follow

Portfolio highlights

  • LookSharp — The industry leader for qualified and diverse candidates to get discovered and hired. Search for job and internship opportunities, access career advice, and connect directly with top employers.
  • Practice Fusion — 'Deliver better care more efficiently with the #1 electronic health record. Our industry-leading EHR was developed with feedback from over 150,000 professionals.'
  • Second Front Systems — The continuous accreditation and deployment of commercial software is crucial for U.S. national security missions. With Second Front Systems' Game Warden platform, you'll be achieving exactly that.
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Sahsen Ventures
VC Fund · Seattle, Washington, United States · 10 investments in United States Life Science startups

Sahsen Ventures is a venture capital firm making investments in for-profit and nonprofit organizations with an emphasis on technology and biotechnology. It was established in 2016 and is based in Seattle, Washington.

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Investment focus

  • Industry: Biotechnology, Health Care, Non Profit
  • Stage:Seed, Series A
  • Geography: United States, China, Ghana

Investor stats

  • Total investments: 85
  • Round size: Seed $1.2M–$25M; Series A $13M–$81M
  • Lead/follow: 0% lead, 100% follow

Portfolio highlights

  • Outpace Bio — Outpace Bio is a biotechnology company that creates smart cell therapies aimed at improving efficacy and safety.It offers a platform that combines custom-designed biological functions with cellular control modalities that program the right response at the right time and place. It creates a mechanism-driven solution tailor-made to improve efficacyand safety. The company collaborates with Lyell Immunopharma to develop and commercialize a potential immune cell therapy for the treatment of cancer, auto-immune diseases, infectious diseases, degenerative diseases, regenerative medicine, metabolic disorders, and genetic disorders, enabling healthcare providers to cure a wide range of diseases as per patient's need.
  • Synthesize Bio — Deep biomedical data is the key to unlocking discoveries and creating therapies. Synthesize Bio uses AI to reduce data collection and analysis from months to minutes for a fraction of the cost in time, personnel, and materials.
  • Archon Biosciences — Archon is a biotechnology firm that creates computationally engineered proteins to unleash potent therapeutic targets beyond the grasp of current methods and improve disease management.
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KdT Ventures
VC Fund · Austin, Texas, United States · 10 investments in United States Life Science startups

KdT Ventures is the standard for early-stage frontier science investing.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Seed, Series A, Series B
  • Geography: United States, India, Canada

Investor stats

  • Total investments: 89
  • Round size: Seed $2.6M–$13M; Series A $8.5M–$70M; Series B $25M–$175M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: Likely still investing — raised $80M in 2022

Portfolio highlights

  • Elegen — Skip cloning with the only entirely cell-free DNA synthesis provider. Sequences up to 7 kb. Error rates as low as 1:70,000/bp. Manufactured in USA, NGS-verified and shipped globally in as few business days.
  • Checkerspot — A biology-driven platform creating specialized lipids from fermentation
  • Tierra Biosciences — Speed, scale and simplicity with protein synthesis on-demand. Discover your portal to thousands of custom proteins. Get testable material with a single input.
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MPM Capital
VC Fund · Cambridge, Massachusetts, United States · 10 investments in United States Life Science startups

Powering Breakthroughs in Life Sciences

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Series B, Series A, Series C
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 225
  • Round size: Series A $9M–$84M; Series B $20M–$125M; Series C $12M–$100M
  • Lead/follow: 35% lead, 65% follow
  • Last fund: Likely still investing — raised $850M in 2021

Portfolio highlights

  • Chiasma — We are a commercial stage pharmaceutical company focused on developing and delivering innovative new treatments that help improve the lives of people with rare diseases.
  • Syndax Pharmaceuticals — Syndax Pharmaceuticals is a clinical-stage pharmaceutical company that focuses on an HDAC inhibitor for solid tumors and hematological tumors. It offers therapies to treat solid tumors and lung, breast, and hematological cancer. The company is developing axatilimab, a monoclonal antibody that blocks the colony-stimulating factor 1 (CSF-1) receptor,in development for chronic Graft versus Host Disease, and entinostat, a class I HDAC inhibitor.Syndax Pharmaceuticals pipeline includes and SNDX-5613, a highly selective inhibitor of the Menin–MLL binding interaction, in development for the treatment of patients with MLLr and NPM1 acute leukemias.
  • Portola Pharmaceuticals — As Alexion, AstraZeneca Rare Disease, we are delivering life-changing therapies to people living with rare diseases.
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SR One
VC Fund · Cambridge, Massachusetts, United States · 10 investments in United States Life Science startups

SR One Capital Management is a leading trans-Atlantic biotech venture capital firm that partners with top entrepreneurs, scientists and investment partners to seek to build elite biotechnology companies. Our mission is to translate ground-breaking technologies into next generation medicines to benef

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 189
  • Round size: Series A $3.7M–$140M; Series B $15M–$114M; Series C $22M–$150M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Turning Point Therapeutics — The Investor Relations website contains information about Turning Point Therapeutics, Inc.'s business for stockholders, potential investors, and financial analysts.
  • Nkarta Therapeutics — Nkarta seeks to improve upon the efficacy of cell therapy, making it more potent, better tolerated and more rapidly available to a broad population of patients with a variety of hematologic and solid tumor malignancies.While T-cell therapy, often known as CAR-T, has proven successful in certain cancer indications, its promise has been limited toa few hematologic malignancies and the side effects can be severe. Natural Killer cells are the immune system’s first responders against diseases and pathogens. Unlike T cells, they have an inherent ability to target tumor cells without genetic alteration, and therefore hold significant promise in the development of potent therapies that can be used more readily for diverse tumor types. Nkarta’s differentiated cell therapy approach is designed to boost and enhance the inherent power of Natural Killer cells to target and destroy tumor cells, while also offering a better tolerated safety profile.
  • River Vision Development — River Vision Development develops RV001, a protein therapy for the treatment of Graves’ Orbitopathy (GO). River Vision Development was founded in 2011 and is based in New York, New York.
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Flagship Pioneering
VC Fund · Cambridge, Massachusetts, United States · 10 investments in United States Life Science startups

We create breakthroughs in human health and sustainability and build bioplatform companies . Companies founded

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series C, Series A
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 199
  • Round size: Series A $5.5M–$88M; Series B $11M–$140M; Series C $12M–$123M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • Montai Therapeutics — Harnessing untapped diverse chemistry with AI-enabled drug discovery to develop breakthrough small molecule medicines for chronic disease.
  • Quotient Therapeutics — Discover how Quotient is pioneering a new field of genetics with somatic genomics to unveil a universe of genetic information and develop new therapies.
  • Ampersand Biomedicines — Ampersand is enabling potent mechanisms to treat disease by creating and programming therapeutics that are more efficacious, without compromising on safety or tolerability.
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Omega Funds
VC Fund · Boston, Massachusetts, United States · 10 investments in United States Life Science startups

We aim to invest in exceptional founders and entrepreneurs and impactful products and platforms across multiple therapeutic areas.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, United Kingdom

Investor stats

  • Total investments: 149
  • Round size: Series A $16M–$197M; Series B $35M–$162M; Series C $14M–$208M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Ousia Pharma — Ousia Pharma is paving the way for novel therapeutic strategies using peptide-drug-conjugates
  • Andrew Alliance — OneLab is laboratory software to design and execute liquid handling protocols. Pipette+ for manual liquid handling pipetting and Andrew+ the pipetting robot
  • NRG Therapeutics — energizing drug discovery in neurodegenerative diseases.
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Cormorant Asset Management
VC Fund · Boston, Massachusetts, United States · 10 investments in United States Life Science startups

Cormorant Asset Management is an employee-owned hedge fund sponsor that provides its services to pooled investment vehicles. The firm also focuses on both public and private market innovative companies in the biotechnology and life sciences marketplace.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series C, Series A
  • Geography: United States, China, Switzerland

Investor stats

  • Total investments: 186
  • Round size: Series A $16M–$102M; Series B $35M–$150M; Series C $33M–$200M
  • Lead/follow: 24% lead, 76% follow
  • Last fund: May invest from a new fund soon — raised $393M in 2019

Portfolio highlights

  • Axonis Therapeutics — AXONIS Therapeutics, Inc. is advancing breakthrough discoveries to develop first-in-class therapies for neurological disorders.
  • GC Therapeutics — Discover GC Therapeutics, a pioneer in scalable, cutting-edge cell therapies designed to revolutionize treatment across a broad range of therapeutic areas.
  • Rapport Therapeutics — Precision medicines to match the complexity of the human brain.
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Alumni Ventures
VC Fund · Manchester, New Hampshire, United States · 9 investments in United States Life Science startups

Access curated startup investment opportunities and diversified venture capital exposure designed for accredited investors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 1428
  • Round size: Seed $1.4M–$10M; Series A $5.2M–$37M; Series B $12M–$79M
  • Lead/follow: 14% lead, 86% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • CesiumAstro — CesiumAstro builds high-throughput, software-defined phased array communication payloads for airborne and in-orbit platforms.
  • Lincode — The #1 business challenge that manufacturers identify is quality management. As new manufactured products continue to enter the market and consumer expectations shift faster than ever, factories are looking to improve their quality systems while scaling operations and cutting costs. At Lincode, we enable manufacturers to improve the speed, accuracy, and data tracking capabilities of their quality inspection systems at scale.
  • Arda Therapeutics — Arda Therapeutics is a biotechnology company taking aim at chronic diseases and aging by eliminating the pathogenic cells that drive these conditions. Their approach starts by using single-cell data to identify pathogenic cells and specific markers to target them. They then design therapies to eliminate these - and only these - cells.Arda wasfounded in 2021 in the San Francisco Bay Area, CA.
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Catalio Capital Management
VC Fund · Baltimore, Maryland, United States · 9 investments in United States Life Science startups

Catalio Capital Management was created by George Petrocheilos and Dr. Jacob Vogelstein to invest in breakthrough biomedical technology companies created or referred by Catalio Capital Management, an elite group of world-renowned, serial scientist-entrepreneurs.

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Investment focus

  • Industry: Biotechnology, Health Care, Life Science
  • Stage:Series A, Series B
  • Geography: United States, Switzerland, Israel

Investor stats

  • Total investments: 116
  • Round size: Series A $18M–$120M; Series B $26M–$150M
  • Lead/follow: 28% lead, 72% follow

Portfolio highlights

  • Avava — Avava is a Pioneer precision skin therapy to improve the quality of life for patients around the world.
  • OSPRI — Multiplex qPCR reagent kits for assay development, biomarker discovery, and translational research. 120+ configurations across a broad range of research areas. Extraction-free. Customizable. For Research Use Only.
  • Medical Informatics — Medical Informatics offers solutions that give care teams access to the data they need to take action for alarm management and safety. The company’s Sickbay software platform enables continuous data collection from a comprehensive set of devices. Ultimately their alarm management solutions reduce alarm noise at the patient level, and send the rightalarms to care providers.Medical Informatics Corp was founded by Emma Fauss and Craig Rusin in 2010 and is based in Houston, Texas.
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Rev1 Ventures
VC Fund · Columbus, Ohio, United States · 9 investments in United States Life Science startups, 6 in the past 12 months

Rev1 Ventures provides seed stage venture capital funding in Columbus, Ohio along with startup services, space, mentoring, and connections. Learn more!

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A
  • Geography: United States, Germany

Investor stats

  • Total investments: 195
  • Round size: Seed $192k–$3.2M; Series A $1.2M–$18M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — raised $20M in 2021

Portfolio highlights

  • FinOpsly — Maximize your cloud ROI with FinOpsly. Our AI-driven platform empowers organizations with smart cost management, fostering collaboration across teams for over 32% in savings. Simplify your cloud strategy with FinOpsly.
  • InnerActiv — InnerActiv is a cybersecurity software company that protects organizations from insider threats, fraud, and data loss at the endpoint. Built with an AI-driven, behavior-based approach, InnerActiv delivers real-time visibility into how users interact with sensitive data, systems, and devices—detecting risky activity such as data grazing, policytesting, and low-and-slow reconnaissance before it leads to a breach. The platform’s lightweight, encrypted agents and endpoint-first design provide proactive protection, faster response, and seamless integration with existing security stacks.
  • Niobium Microsystems — The encrypted cloud has arrived.
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Lux Capital
VC Fund · New York, New York, United States · 9 investments in United States Life Science startups

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 521
  • Round size: Seed $1.8M–$30M; Series A $7M–$60M; Series B $13M–$150M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: May invest from a new fund soon — raised $100M in 2007

Portfolio highlights

  • Clarifai — Clarifai is the leading Machine Learning, Computer Vision, NLP Platform. Label, train, deploy models on one AI platform for developers & data scientists.
  • Primer — Primer makes powerful mission-ready AI software designed to work in your environment, on your data. We help national security teams sift through massive unstructured data sets to find the needle in the haystack, understand and visualize their data, and act collaboratively. Our mission is to empower decisions that can be defended, and acted upon confidently.
  • Impulse Space — Economical and nimble last-mile space payload delivery
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Versant Ventures
VC Fund · Menlo Park, California, United States · 9 investments in United States Life Science startups

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 282
  • Round size: Series A $4.7M–$80M; Series B $10M–$105M; Series C $12M–$108M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Stablix — Stablix is pioneering an entirely new field of targeted protein stabilization (TPS) to bring transformative medicines to patients with unmet medical need.
  • Passage Bio — Passage Bio, a genetic medicines company, is changing the future of CNS disorders and transforming the lives of patients and their families.
  • Lycia Therapeutics — Lycia Therapeutics is a biotechnology company that focuses on developing technology that utilizes lysosome-targeting chimeras. The company was founded by Carolyn R. Bertozzi in 2019 and is based in San Diego, California, USA.
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Pear VC
VC Fund · Palo Alto, California, United States · 9 investments in United States Life Science startups

Pear VC partners with entrepreneurs from day zero to build category-defining companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States, Brazil, Colombia

Investor stats

  • Total investments: 309
  • Round size: Seed $2.2M–$8.4M; Pre-Seed $500k–$3.7M; Series A $8M–$35M
  • Lead/follow: 21% lead, 79% follow
  • Last fund: Likely still investing — raised $432M in 2023

Portfolio highlights

  • Thena — Deliver world class customer experiences right inside Slack and Microsoft Teams with Thena
  • Axle Health — Axle Health provides scheduling and workforce management software to help home healthcare and hospice providers improve their clinician productivity.
  • Socratix AI — Socratix AI offers autonomous AI agents designed to serve as enterprise-grade fraud and risk analysts.
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Longwood Fund
VC Fund · Boston, Massachusetts, United States · 9 investments in United States Life Science startups

Longwood creates and invests in science-based companies that develop novel solutions for important medical problems

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Investment focus

  • Industry: Biotechnology, Therapeutics, Health Care
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Italy

Investor stats

  • Total investments: 74
  • Round size: Series A $16M–$100M; Series B $25M–$152M; Series C $17M–$100M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: Likely still investing — fund raised in 2023

Portfolio highlights

  • Pulmocide — Pulmocide is developing novel inhaled medicines for serious respiratory diseases
  • Recros Medica — Recros Medica, Inc. is a development stage medical aesthetic device company focused on developing a platform technology to reduce skin laxity and improve focal aesthetic contour deformities. The company was incorporated in 2014 and is based in San Diego, California.
  • Calithera Biosciences — Calithera is developing first-in-class small molecule drugs that slow tumor growth through controlling key metabolic pathways in the tumor and immune cells.
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Gaingels
VC Fund · New York, New York, United States · 8 investments in United States Life Science startups

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Mexico

Investor stats

  • Total investments: 755
  • Round size: Seed $1.4M–$8M; Series A $6M–$40M; Series B $16M–$100M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely actively investing — fund raised in 2024

Portfolio highlights

  • Paxton — Regulatory Intelligence, with the speed of Generative AI.
  • Limbic — Limbic creates neuroscience of emotion packaged for developers. With just a few lines of code, anyone can make their app emotionally intelligent. Use the SDK to build products that interact with your user as naturally as interactions between two humans.
  • Sharper Sense — Neuromodulation for Clear Senses
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Biotechnology Value Fund
VC Fund · San Francisco, California, United States · 8 investments in United States Life Science startups

Biotechnology Value Fund is a San Francisco-based private investment partnership specializing in fundamentally-driven public biotechnology investments.Since its inception in 1993, BVF has strived to build concentrated, long-term investments in small-cap biotechnology companies while performing rigorous diligence and on-going monitoring of itsinvestments.BVF is committed to working with its portfolio companies as partners in their successes.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Post-IPO Equity, Series B, Series A
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 141
  • Round size: Series A $6.1M–$176M; Series B $40M–$143M; Post-IPO Equity $16M–$165M
  • Lead/follow: 24% lead, 76% follow

Portfolio highlights

  • AltruBio — AltruBio is focused on developing targeted antibody therapeutics for the treatment of cancer and immune-related inflammatory diseases.AltruBio International in Delaware with principal office in SFO Bay Area California is a biopharmaceutical company integrated globally and virtually to develop targeted antibody therapeutics for the treatment ofcancer and immune-related inflammatory diseases.With its R&D foundation in Taipei Taiwan since June 2000, AbGenomics has been focusing on the discovery and development of novel therapeutics for unmet medical needs.Their R&D scientists built an efficient discovery platform to identify and validate novel antibody therapeutics.Currently, AbGenomics has several potential therapeutic antibodies targeting autoimmune diseases, pancreatic cancer, stomach cancer, colorectal cancer, ovarian cancer, lung cancer, and other solid tumors in various development stages.
  • Nimbus Therapeutics — Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company. Nimbus Therapeutics is a biotechnology company headquartered in Cambridge, Mass., that is pioneering a new computational technology-driven paradigm to rapidly advance a diverse pipeline of novel small molecule product candidates into clinicaldevelopment. We are designing highly selective and potent medicines to disrupt known drivers of serious diseases, including metabolic disease, cancer and immune-inflammatory disorders.
  • Olema Oncology — Olema Oncology is a clinical-stage biopharmaceutical company developing novel therapies to transform treatment for metastatic breast cancer and beyond.
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Playground Global
VC Fund · Palo Alto, California, United States · 8 investments in United States Life Science startups

Playground Global is an early-stage venture capital firm backing technical and scientific founders with deep engineering expertise, a collaborative environment, and a first-hand understanding of the intricacies of deep tech. Established in 2015 and headquartered in Palo Alto, CA, Playground’s mission is to transform ambitious ideas into impactfulbusinesses that benefit humanity and the planet. We invest in areas that span across next gen compute automation, energy transition and engineered biology. Playground has been an early – and frequently first investor – in companies that include PsiQuantum, Relativity Space, Ultima Genomics, MosaicML (acq. by Databricks), d-Matrix, and Strand Therapeutics.

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Investment focus

  • Industry: Software, Robotics, Biotechnology
  • Stage:Series A, Series B, Seed
  • Geography: United States, Canada, Italy

Investor stats

  • Total investments: 137
  • Round size: Seed $2.2M–$20M; Series A $7M–$35M; Series B $20M–$153M
  • Lead/follow: 48% lead, 52% follow
  • Last fund: Likely still investing — raised $410M in 2023

Portfolio highlights

  • Velo3D — Design, print and produce critical metal parts with Velo3D's advanced laser powder bed fusion technology. Trusted by aerospace, defense, and energy leaders.
  • Saltbox — Saltbox makes the hardest parts of running an ecommerce business simple. Explore our logistics and warehouse solutions growing eCommerce companies
  • Strand Therapeutics — Clinical-stage biotech developing breakthrough mRNA therapeutics with targeted delivery systems for solid tumors, autoimmune diseases, and blood cancers.
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5AM Ventures
VC Fund · Menlo Park, California, United States · 8 investments in United States Life Science startups

5AM Ventures is a venture capital firm that offers seed- and early-stage investments to its clients. The company’s client portfolio consists of firms in the biopharmaceutical, life sciences, medical technology, and research instrument industries. 5AM Ventures was founded in 2002 by John Diekman and Andrew Schwab and is based in California.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, United Kingdom

Investor stats

  • Total investments: 178
  • Round size: Series A $13M–$70M; Series B $16M–$110M; Series C $14M–$100M
  • Lead/follow: 36% lead, 64% follow
  • Last fund: Likely still investing — raised $450M in 2022

Portfolio highlights

  • Neurogastrx — Neurogastrx, Inc. is a venture-stage biopharmaceutical company developing products for the treatment of gastrointestinal disorders.
  • Vor Biopharma — Vor Bio is a clinical-stage biotechnology company transforming the treatment of autoimmune diseases. Our goal is to bring life-changing therapies to patients worldwide who are living with serious, autoantibody-driven conditions.
  • Cleave Therapeutics — Cleave Therapeutics develops oncology pharmaceuticals designed to target neurodengeneration and pathways used by cancer cells to grow. The company is engaged in the discovery of novel, small-molecule drugs that affect protein-degradation pathways, upon which cancer cells depend for survival, enabling patients to get cured from cancer.
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The Column Group
VC Fund · San Francisco, California, United States · 8 investments in United States Life Science startups

The Column Group (TCG) is a venture ecosystem dedicated to fueling scientific innovation in the life sciences industry.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States

Investor stats

  • Total investments: 138
  • Round size: Series A $9.2M–$102M; Series B $22M–$120M; Series C $33M–$107M
  • Lead/follow: 37% lead, 63% follow

Portfolio highlights

  • Exonics Therapeutics — Exonics’ laboratory has demonstrated the ability to use adeno-associated virus (AAV) to deliver a payload based on CRISPR/Cas9 technology that can identify and correct exon mutations that prevent the production of dystrophin, a protein that helps stabilize and protect muscle fibers.
  • Revolution Medicines — Revolution Medicines is developing new therapies through an innovative approach that harnesses the complex chemicals of life by reconfiguring natural substances into best-in-class medicines.REVOLUTION Medicines builds upon the vision of the company’s founder, Martin D. Burke, M.D., Ph.D., professor of chemistry, University of Illinois atUrbana-Champaign, and Early Career Scientist of the Howard Hughes Medical Institute, who invented a transformative method for synthesizing original compounds that are pharmaceutically optimized analogues of complex natural products. REVOLUTION Medicines has entered into an exclusive license agreement with the University of Illinois to practice and expand this technology.REVOLUTION Medicines’ approach is a rapid, standardized and powerful process for assembling simple “chemical building blocks” into refined natural product-like structures. These optimized compounds have significant potential as best-in-class drug candidates.
  • Constellation Pharmaceuticals — Constellation Pharmaceuticals is the first biopharmaceutical company dedicated to the development of novel therapeutics in the emerging field of Epigenetics, a new field of science which is focused on selective regulators of epigenetic function, which are critical to controlling gene expression.
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Apple Tree Partners
VC Fund · New York, New York, United States · 8 investments in United States Life Science startups

ATP, a global leader in life sciences venture capital, is developing the next generation of transformative biotechnology companies. ATP creates science-based companies starting with assets at various stages: from working with scientists on pre-IP ideas, to spinouts from existing company pipelines. The firm provides flexible capital, strategicinsight, and operational resources to build sustainable, research-driven enterprises. ATP invests in its portfolio companies from seed stage through IPO and beyond and supports their management teams in strategic transactions and synergistic business combinations.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Seed
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 63
  • Round size: Seed $3.8M–$8M; Series A $10M–$75M; Series B $9.3M–$90M
  • Lead/follow: 56% lead, 44% follow
  • Last fund: May invest from a new fund soon — raised $1B in 2020

Portfolio highlights

  • Adendra Therapeutics — Adendra is an emerging biotechnology company building on new insights into dendritic cell biology to discover and develop new small molecule and biologic medicines for the treatment of a wide range of cancers and autoimmune diseases.
  • Red Queen Therapeutics — Staying ahead of viral threats with new innovations in antiviral therapy
  • Deep Apple Therapeutics — Deep Apple Therapeutics is discovering new small-molecule therapeutics with unprecedented speed and exceptional acumen.
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New Enterprise Associates
VC Fund · Menlo Park, California, United States · 8 investments in United States Life Science startups

Foundational partners to ambitious founders at every stage of company-building.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series A, Series B, Series C
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1539
  • Round size: Series A $5.3M–$60M; Series B $10M–$80M; Series C $13M–$103M
  • Lead/follow: 40% lead, 60% follow
  • Last fund: Likely still investing — raised $2.8B in 2022

Portfolio highlights

  • Perplexity — Perplexity is a search engine platform that uses artificial intelligence to provide large language models and search engines. The company's platform enables the development of beneficial artificial general intelligence, as well as an open-source environment that is accessible to the public, allowing clients to develop skills and knowledge inartificial intelligence.
  • Allay Therapeutics — SUPPORTING PATIENTS THROUGH EVERY PHASE OF RECUPERATION The first technology designed to deliver weeks of localized pain management
  • Regulus Therapeutics — Regulus Therapeutics Is a biopharmaceutical company leading the discovery of a new class of high-impact medicines based on microRNAs. The discovery of MicroRNA in humans is one of the most exciting scientific breakthroughs in the last decade. MicroRNAs are small RNA molecules, typically 20 to 25 nucleotides in length, that do not encode proteinsbut instead regulate gene expression. It was founded in 2007 and is headquartered in Carlsbad, California.
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Digitalis Ventures
VC Fund · New York, New York, United States · 8 investments in United States Life Science startups

Engineering solutions to complex problems in health through venture investment and company creation.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 97
  • Round size: Seed $1.5M–$16M; Series A $6.4M–$66M; Series B $13M–$132M
  • Lead/follow: 16% lead, 84% follow

Portfolio highlights

  • PetMedix — PetMedix develops next-generation antibody therapies for pets, using advanced biotechnology to create safer, more effective treatments for animal health.
  • Scout Bio — Scout Bio is a biotechnology company that specializes in veterinary, animal health, and gene therapy. The company is driven by its mission is to harness the genetic revolution transforming human medicine to deliver the future of veterinary medicine. Scout Bio was founded in 2016 and headquartered in Pennsylvania, United States.
  • Scratch — Scratch Financial is the nation's largest provider of simple, pet-friendly payment plans for veterinary care. Scratch Financial partners with veterinary clinics and provides pet owners with simple, friendly payment plans. Pet owners can apply, review, and accept a scratchpay.com payment plan in 90 seconds.
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iSelect Fund
VC Fund · St Louis, Missouri, United States · 8 investments in United States Life Science startups

Venture investing in Food, Health, and AgTech. A generational investment thesis. Food is Health is longevity

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Investment focus

  • Industry: Biotechnology, Health Care, Agriculture
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Australia

Investor stats

  • Total investments: 92
  • Round size: Seed $100k–$12M; Series A $3.3M–$50M; Series B $8.3M–$59M
  • Lead/follow: 14% lead, 86% follow
  • Last fund: May invest from a new fund soon — raised $3.8M in 2019

Portfolio highlights

  • Bractlet — From utility bill management to predicting the future with simulations, Bractlet provides a single software solution to optimize building performance and reduce emissions, at scale.
  • Miraterra — A New Era of Measurement: Unlocking the Secrets of Soil, Plants, and Food. Our breakthrough technology, overcoming decades of limitations, provides fast, efficient and trustworthy digital measurements when and where you need them most.
  • Flywheel.io — Flywheel is a data management and analysis platform built specifically for scientists and the researcher's workflow. They empower research momentum by focusing on data and medical image capture, content management, scientific computation, and collaboration. With reproducible research in mind, they combine open-source methods from topuniversities, a modern web user interface, and an extensible compute engine based on containerization technology. The result is a software platform to accelerate discovery and help researchers do science, not IT.Flywheel accelerates new scientific discoveries in life-science, biotech, and academic imaging research through cloud-scale collaboration. As a result, imaging researchers are able to avoid innovation bottlenecks, and accelerate discovery by doing more science, and less IT.
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Khosla Ventures
VC Fund · Menlo Park, California, United States · 8 investments in United States Life Science startups

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Series B, Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1085
  • Round size: Seed $2M–$17M; Series A $5.5M–$44M; Series B $10M–$100M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely still investing — raised $557M in 2022

Portfolio highlights

  • Fundbox — Fundbox offers fast, easy access to business financing, up to $150,000. Learn how our line of credit and term loan options can unlock growth for your business.
  • Even — Even is a health tech company and healthcare provider that partners directly with the top hospitals in the country to offer you unlimited diagnostics, consultations, and 50 lakh worth of hospitalisations all with one monthly subscription cost.
  • Loop — Loop Health is bringing ease and choice to patients seeking major medical treatments. We've brought together family physicians, top specialists, and leading hospitals in Pune – to provide options, transparency, and ease to patients and their families. Loop Coordinators help patients match with a doctor, compare treatment costs, get secondopinions, and complete admission formalities – removing the stress and making lives easier for the patient and their families.
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Vivo Capital
VC Fund · Palo Alto, California, United States · 8 investments in United States Life Science startups

The firm is a 25-year-old global investment firm focused on healthcare with approximately $5.8 billion in AUM, which we have invested in over 290 public and private companies worldwide. Headquartered in Palo Alto, California, with offices in Asia. Our team consists of 50 multi-disciplinary professionals, including, physicians, scientists,entrepreneurs, operating executives, and industry experts. The firm operates as a multi-fund investment platform, covering growth equity, private equity including buyout, venture capital, and public equity. Vivo invests broadly in healthcare across all fund strategies, including biotechnology, pharmaceuticals, medical devices, and healthcare services, with a focus on the largest healthcare markets.

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Post-IPO Equity, Series B, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 222
  • Round size: Series B $28M–$125M; Series C $30M–$108M; Post-IPO Equity $40M–$177M
  • Lead/follow: 26% lead, 74% follow
  • Last fund: May invest from a new fund soon — raised $1.4B in 2019

Portfolio highlights

  • Passage Bio — Passage Bio, a genetic medicines company, is changing the future of CNS disorders and transforming the lives of patients and their families.
  • Ronovo Surgical — Founded in 2019 and headquartered in Shanghai, Ronovo Surgical is founded by industry veterans from global leaders in surgical and industrial robotics, such as Intuitive Surgical, Johnson & Johnson, Medtronic and KUKA. Aiming to transform how surgery is performed in China, Ronovo is leveraging robust R&D capabilities and strategicpartnerships globally to accelerate the development of a broad portfolio of MIS and digital surgery solutions that exemplifies the core themes of simplicity, precision, and intelligence.
  • BlossomHill Therapeutics — BlossomHill Therapeutics, Inc. is a small molecule drug discovery and development company focused on unmet medical needs in oncology and autoimmune disorders.
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Oreilly AlphaTech Ventures
VC Fund · San Francisco, California, United States · 7 investments in United States Life Science startups

O'Reilly AlphaTech Ventures (OATV) is in the business of funding disruptors, innovators, and hackers of the status quo. From open source to the early days of the web and its recent resurgence, O'Reilly Media has played a key role as trend spotter and advocate for putting world-changing technologies on the map. OATV effort is to bring thelegacy, resources, and relationships of O'Reilly to each investment they make.

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Investment focus

  • Industry: Software, E-Commerce, Internet
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 125
  • Round size: Seed $650k–$4.2M; Series A $1.4M–$13M; Series B $5.5M–$33M
  • Lead/follow: 12% lead, 88% follow
  • Last fund: May invest from a new fund soon — raised $85M in 2012

Portfolio highlights

  • Pachama — Harnessing AI to drive carbon capture and protect global forests
  • Opensignal — Opensignal is the leading global provider of independent insights into network experience and market performance.
  • littleBits Electronics — LittleBits is an open source library of over 60 electronic modules that snap together with magnets allows users to view, download, and share designs and make their own Bits through the use of prototypes. Deluxe kit, Smart home kit, Arduino coding kit, Synth kit, hardware development kit, and workshop set are some of the electronics learning modulesprovided by littleBits.LittleBits was launched by Ayah Bdeir in 2011 and is operated from New York, United States.
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F-Prime
VC Fund · Cambridge, Massachusetts, United States · 7 investments in United States Life Science startups

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 422
  • Round size: Series A $9.2M–$87M; Series B $16M–$130M; Series C $22M–$115M
  • Lead/follow: 27% lead, 73% follow

Portfolio highlights

  • 1upHealth — 1upHealth is the trusted interoperability solutions provider for health plans looking to acquire, manage, exchange, analyze, and use clinical data and claims data.
  • Simon Data — Simon Data empowers CRM teams with the data, tools, & support to drive personalization at every customer touchpoint.
  • CHARM Therapeutics — CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins.
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Vida Ventures
VC Fund · Boston, Massachusetts, United States · 7 investments in United States Life Science startups

Vida Ventures’ mission is to bring science to life by advancing transformative biomedical innovations that have the potential to make a meaningful impact on the lives of patients. They want to do well by doing good for others. Vida Ventures is a bicoastal life sciences company building and investment firm, founded in 2017 by a group of scientists,physicians, entrepreneurs, and investors who are passionate about building and funding breakthroughs in biomedicine .

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, China, India

Investor stats

  • Total investments: 64
  • Round size: Series A $35M–$250M; Series B $60M–$260M; Series C $60M–$175M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely still investing — raised $825M in 2021

Portfolio highlights

  • Protego Biopharma — Protego Biopharma develops therapeutics based on the clear human genetic link, excellent human safety profile, proof-of-principle efficacy. The company was founded in 2011 and is headquartered in San Diego, California.
  • ReCode Therapeutics — ReCode is the first genetic medicines platform to enable highly targeted delivery to organs, tissues and cells beyond the liver. Our pipeline of rare disease therapeutics uses optimized mRNA and gene correction with redosing capability.
  • Allogene Therapeutics — Allogene Therapeutics is a clinical stage immuno-oncology company. It is mainly engaged in the development and commercialization of genetically engineered allogeneic T cell therapies for the treatment of cancer. The company is involved in developing a pipeline of multiple allogeneic T cell product candidates utilizing validated gene editing andadvanced proprietary cell manufacturing technologies. Its pipeline includes UCART19 which is developed for the treatment of relapsed or refractory acute lymphoblastic leukemia (ALL), as well as several preclinical allogeneic CAR T therapies.
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venBio Partners
VC Fund · San Francisco, California, United States · 7 investments in United States Life Science startups

venBio invests in promising companies at various stages: from early to late stage, and from academic startups to spinouts. We tend to lead most of our investments, and we enjoy building syndicates and teams.We are mindful of potential acquisition partners from the outset, and we ensure that our companies are best positioned to meet theirrequirements. This includes IP, CMC, and the details of clinical trials, including indication, trial design, endpoints, powering, and regulatory considerations. Our team’s expertise and involvement helps companies make a bigger impact, and this leads to impactful and lasting relationships with the leaders that we work with.

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Investment focus

  • Industry: Biotechnology, Health Care, Pharmaceutical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Canada, Switzerland

Investor stats

  • Total investments: 90
  • Round size: Series A $20M–$81M; Series B $39M–$190M; Series C $36M–$259M
  • Lead/follow: 40% lead, 60% follow
  • Last fund: Likely still investing — raised $550M in 2021

Portfolio highlights

  • INBRACE — Behind-the-teeth braces that move your teeth gently and invisibly. InSmile Braces means fewer visits, more confidence, and treatment that works with your life.
  • HistoWiz — HistoWiz is a biotech company that automates the processing and digitizing of tissue samples for pharma and academia.Through its fully automated histology lab and the world’s first online pathologist network, HistoWiz processes and annotates tissue samples which are stored on PathologyMap, its cloud database, as a resource for cancer researchers.The data stored on PathologyMap enables the integration of technology and the development of AI tools for digital pathology on an unprecedented scale.
  • Ablaze Pharmaceuticals — Ablaze Pharma is a clinical stage bio-pharmaceutical company that is focused on developing Targeted Radiotherapy (TRT) to benefit cancer patients.
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Connecticut Innovations
VC Fund · Rocky Hill, Connecticut, United States · 7 investments in United States Life Science startups

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 245
  • Round size: Seed $200k–$5M; Series A $2.4M–$25M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — raised $50M in 2023

Portfolio highlights

  • Device42 — Device42 sets the standard as the most comprehensive, agentless discovery and dependency mapping solution, spanning from legacy mainframes to cloud containers.
  • Mobile Sense — The traditional diagnostic market is being transformed by advances in high performance wearables. This seismic shift led by consumer products which are uncovering new patients who previously went undetected, but still require a detailed diagnosis. Mobile Sense™ is building foundational technology that enables this transformation throughoff-the-chest wearables for long term management of cardiac arrhythmias. Developed over 7 years with $4.2M in grant funding and $1.3M in seed funding, Mobile Sense™ has a platform for differentiated wearables. Our embedded algorithms coupled with non-adhesive, wireless & waterproof sensors provides high fidelity continuous ECG and PPG recordings. The automatic monitoring provides 24/7, 365 days/yr continuous detection and classification of dangerous heart arrhythmias.
  • NovaTract Surgical — NovaTract Surgical is a development stage company, intends to develop medical devices to address the rapidly growing field of Single Incision Laparoscopic Surgery (SILS) and Natural Orifice Transluminal Endoscopic Surgery (NOTES). The company was incorporated in 2010 and is based in Guilford, Connecticut.
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Roche Venture Fund
VC Fund · Basel, Basel-Stadt, Switzerland · 7 investments in United States Life Science startups

The Roche Venture Fund is the name given to the corporate venture fund of the healthcare company Roche. Roche has allocated CHF 500 million to invest in and develop commercially successful innovative life science companies. Roche has been investing in early stage companies as part of collaborations since the early-1990s and independent ofcollaborations since 2002. All equity investments made by Roche in biotech and diagnostics companies (including collaboration investments) are negotiated and managed by the Roche Venture Fund. In the past 20 years, the Roche Venture Fund has invested in over 60 companies globally. Currently, Roche Venture Fund has a portfolio of around 30 companies located in 10 countries across Europe, North America and the Pacific Region. The fund is an evergreen fund with CHF 500 million available of which approximately 40% is currently invested.The Roche Venture Fund is a committed long-term stable investor with sufficient money reserved in their fund for follow-on financing rounds. As part of a multinational healthcare company, the Roche Venture Fund has access to considerable expertise both internally and externally. We co-invest with leading venture funds, including other corporate venture funds, on a regular basis.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series B, Series A, Series C
  • Geography: United States, United Kingdom, Spain

Investor stats

  • Total investments: 110
  • Lead/follow: no public data

Portfolio highlights

  • DiogenX — Welcome to DiogenX. Explore our pioneering research and innovative therapies aimed at transforming diabetes treatment
  • Mironid — Google Analytics is a web analysis service provided by Google. Google utilizes the data collected to track and examine the use of www.mironid.com, to prepare reports on its activities and share them with other Google services. Google may use the data collected to contextualize and personalize the ads of its own advertising network.
  • MISSION Therapeutics — Deubiquitylating enzymes: multiple drug opportunities across therapeutic areas
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Life Science VC funding in United States at a glance

Stats across 2.6k deals from 2.7k investors.

2.7k
investors
in United States Life Science startups
2.6k
deals
in United States Life Science startups
$11M
median round
in United States Life Science startups
40%
lead investors
lead at least one round
19%
Series A
most common funding stage

Access all 2688 VC funds in United States Life Science startups.

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