Top 50 Biotechnology VC Funds & Investors in United States (June 2026)

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• Ultivue — Ultivue is a biotechnology company that specializes in tissue imaging, diagnostics, and multiplexing. Ultivue produces reagents that enable researchers to obtain microscopic images at an unprecedented resolution that helps to understand of biology and medicine. Ultivue's products are designed for fluorescent microscopy-based research and willeventually be valuable for clinical diagnostic use. It was founded in 2015 and headquartered in Cambridge, Massachusetts.
• EGenesis — At eGenesis, we envision a world where transplantation is accessible to all. We develop safe and effective human-compatible organs for transplantation.
• Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.

Portfolio highlights

• miRecule — MiRecule is an early-stage biotechnology company that focuses on developing microRNA-based therapeutics. It features a genomic-based drug development platform that integrates genomic sequencing, expression, and prognostic data from cancer patients. The company was founded in 2016 and headquartered in Gaithersburg, United States.
• Marvin Health — Marvin is a mental health service for physicians. We're ending the one-size-fits-all approach to teletherapy, helping you to set a teletherapy action plan.
• Deep Genomics — Revolutions in AI, biology and automation are enabling a new approach to medicine. Deep Genomics is at the forefront.

Portfolio highlights

• Sonendo — Sonendo developing innovative technologies to transform dentistry by Saving Teeth Through Sound Science®. The GentleWave® System shows significant improvements in clinical efficacy and practice efficiency when compared to standard root canal treatment.1,2, 3 Sonendo is the parent company of TDO® Software, the developer of the most widely usedendodontic practice management software in the world, designed to simplify practice workflow. TDO software seamlessly integrates practice management, imaging, social media, referral reporting, CBCT imaging, and offers built-in communication with the GentleWave System.
• Crown Bioscience — Crown Bioscience is an expert preclinical contract research organization providing oncology services and preclinical cancer models for drug development. Crown Biocience brings clarity to drug discovery worldwide, helping companies solve today's most pressing problems in immuno-oncology, oncology, cardiovascular, and metabolic diseases.
• Aspen Neuroscience — personalized cell therapy Starts with you Learn More about our technology

Portfolio highlights

• Judo Bio — Judo Bio is pioneering oligonucleotide medicines delivered to the kidney, opening the way for new treatments for systemic and renal diseases.
• Nimbus Therapeutics — Nimbus Discovery is now Nimbus Therapeutics to reflect our transition into a clinical stage company. Nimbus Therapeutics is a biotechnology company headquartered in Cambridge, Mass., that is pioneering a new computational technology-driven paradigm to rapidly advance a diverse pipeline of novel small molecule product candidates into clinicaldevelopment. We are designing highly selective and potent medicines to disrupt known drivers of serious diseases, including metabolic disease, cancer and immune-inflammatory disorders.
• Remix Therapeutics — Remix Therapeutics is a biotechnology company that develops novel small molecule therapies designed to reprogram RNA processing and treat disease in entirely new ways.

Portfolio highlights

• Perplexity — Perplexity is a search engine platform that uses artificial intelligence to provide large language models and search engines. The company's platform enables the development of beneficial artificial general intelligence, as well as an open-source environment that is accessible to the public, allowing clients to develop skills and knowledge inartificial intelligence.
• Allay Therapeutics — SUPPORTING PATIENTS THROUGH EVERY PHASE OF RECUPERATION The first technology designed to deliver weeks of localized pain management
• Regulus Therapeutics — Regulus Therapeutics Is a biopharmaceutical company leading the discovery of a new class of high-impact medicines based on microRNAs. The discovery of MicroRNA in humans is one of the most exciting scientific breakthroughs in the last decade. MicroRNAs are small RNA molecules, typically 20 to 25 nucleotides in length, that do not encode proteinsbut instead regulate gene expression. It was founded in 2007 and is headquartered in Carlsbad, California.

Portfolio highlights

• Stablix — Stablix is pioneering an entirely new field of targeted protein stabilization (TPS) to bring transformative medicines to patients with unmet medical need.
• Passage Bio — Passage Bio, a genetic medicines company, is changing the future of CNS disorders and transforming the lives of patients and their families.
• Lycia Therapeutics — Lycia Therapeutics is a biotechnology company that focuses on developing technology that utilizes lysosome-targeting chimeras. The company was founded by Carolyn R. Bertozzi in 2019 and is based in San Diego, California, USA.

Portfolio highlights

• Thirty Madison — Thirty Madison is a human-first healthcare company, powering access to affordable specialized healthcare through brands like Keeps and Cove.
• CliQr Technologies — CliQr is a leading provider of application-defined cloud management solutions. Offering full lifecycle management delivered in a single, intuitive packaged platform, CliQr enables businesses to easily and efficiently model, deploy and manage one to many applications, users, and clouds.CliQr’s application-defined technology de-couplesapplications from the complexity of hybrid cloud environments, allowing them to securely move, deploy and manage new and existing application across any physical, virtual or cloud environment.CliQr’s patented and patent-pending technology and its global partners help dozens of leading brands in healthcare, manufacturing and technology markets manage their cloud application lifecycles in over 15 different data center, private and public cloud environments.Headquartered in San Jose, California, with locations in Canada, India and Czech Republic, CliQr is backed by Polaris Partners, Foundation Capital, Google Ventures and TransLink Capital. For additional information, visit www.cliqr.com.
• Invivyd — Adagio is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization of antibody-based solutions for infectious diseases with pandemic potential. The company’s portfolio of antibodies has been optimized using Adimab’s industry-leading antibody engineering capabilities and is designed to provide patientsand clinicians with a powerful combination of potency, breadth, durable protection (via half-life extension), manufacturability and affordability. Adagio’s portfolio of SARS-CoV-2 antibodies includes multiple, non-competing broadly neutralizing antibodies with distinct binding epitopes, led by ADG20. Adagio has secured manufacturing capacity for the production of ADG20 with thirdparty contract manufacturers through the completion of clinical trials and, if approved by regulatory authorities, through initial commercial launch.

Portfolio highlights

• HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
• Insignum AgTech — Insignum AgTech develops biotech plants that communicate with producers, alerting them to an illness in its early stages.
• Rescue Forensics — Customer service is our #1 priority. Get a premium domain for your website today. Financing available.

Portfolio highlights

• Fundbox — Fundbox offers fast, easy access to business financing, up to $150,000. Learn how our line of credit and term loan options can unlock growth for your business.
• Even — Even is a health tech company and healthcare provider that partners directly with the top hospitals in the country to offer you unlimited diagnostics, consultations, and 50 lakh worth of hospitalisations all with one monthly subscription cost.
• Loop — Loop Health is bringing ease and choice to patients seeking major medical treatments. We've brought together family physicians, top specialists, and leading hospitals in Pune – to provide options, transparency, and ease to patients and their families. Loop Coordinators help patients match with a doctor, compare treatment costs, get secondopinions, and complete admission formalities – removing the stress and making lives easier for the patient and their families.

Portfolio highlights

• CytomX Therapeutics — CytomX Therapeutics is a biotechnology company that focuses on developing proteolytically-activated antibodies. Their mission, alone and with the help of partners, is to provide patients with more effective and less toxic therapies for severe illnesses such as cancer and inflammatory diseases.
• Rapport Therapeutics — Precision medicines to match the complexity of the human brain.
• Synnovation Therapeutics — Synnovation Therapeutics is a precision oncology company focused on small molecule therapies optimized to target key driver mechanisms in cancers. It is dedicated to the discovery and development of therapeutics that can improve the lives of people with cancer. Leveraging its deep expertise in medicinal chemistry, cancer biology, andpatient-focused precision medicine, it builds a diverse pipeline of novel small-molecule targeted therapies. It aims to efficiently advance these agents into clinical trials with the goal of transforming cancer patient care.

Portfolio highlights

• Neurogastrx — Neurogastrx, Inc. is a venture-stage biopharmaceutical company developing products for the treatment of gastrointestinal disorders.
• Vor Biopharma — Vor Bio is a clinical-stage biotechnology company transforming the treatment of autoimmune diseases. Our goal is to bring life-changing therapies to patients worldwide who are living with serious, autoantibody-driven conditions.
• Cleave Therapeutics — Cleave Therapeutics develops oncology pharmaceuticals designed to target neurodengeneration and pathways used by cancer cells to grow. The company is engaged in the discovery of novel, small-molecule drugs that affect protein-degradation pathways, upon which cancer cells depend for survival, enabling patients to get cured from cancer.

Portfolio highlights

• Chiasma — We are a commercial stage pharmaceutical company focused on developing and delivering innovative new treatments that help improve the lives of people with rare diseases.
• Syndax Pharmaceuticals — Syndax Pharmaceuticals is a clinical-stage pharmaceutical company that focuses on an HDAC inhibitor for solid tumors and hematological tumors. It offers therapies to treat solid tumors and lung, breast, and hematological cancer. The company is developing axatilimab, a monoclonal antibody that blocks the colony-stimulating factor 1 (CSF-1) receptor,in development for chronic Graft versus Host Disease, and entinostat, a class I HDAC inhibitor.Syndax Pharmaceuticals pipeline includes and SNDX-5613, a highly selective inhibitor of the Menin–MLL binding interaction, in development for the treatment of patients with MLLr and NPM1 acute leukemias.
• Portola Pharmaceuticals — As Alexion, AstraZeneca Rare Disease, we are delivering life-changing therapies to people living with rare diseases.

Portfolio highlights

• Curevo — focused on a new generation of adjuvanted subunit vaccines Learn More Our Focus We're dedicated to developing non-mRNA vaccines for unmet medical needs Curevo Vaccine is a clinical-stage biotech company dedicated to developing next-generation non-mRNA vaccines. We focus on one need at a time, allowing us to bring effective and better-tolerated vaccines to market quickly
• ADCendo — ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs. We focus on antibody-drug conjugates (ADCs) directed at novel targets, that have been found to be overexpressed by several cancer forms, that are all characterized by a significant unmet need for novel treatment.
• Terrestrial Bio — Vaxess engineers novel technologies that uniquely engage the human immune system, enabling improved efficacy and simplified access for vaccines and therapeutics.

Portfolio highlights

• Axle Health — Axle Health provides scheduling and workforce management software to help home healthcare and hospice providers improve their clinician productivity.
• CHARM Therapeutics — CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins.
• RightHand Robotics — RightHand Robotics offers advanced robotic piece-picking technology for efficient and predictable order fulfillment. Contact us today to learn how.

Portfolio highlights

• Verishop — Shop designer clothing, shoes, bags and accessories from top Italian boutiques. Discover the latest luxury fashion at competitive prices with global shipping.
• Lincode — The #1 business challenge that manufacturers identify is quality management. As new manufactured products continue to enter the market and consumer expectations shift faster than ever, factories are looking to improve their quality systems while scaling operations and cutting costs. At Lincode, we enable manufacturers to improve the speed, accuracy, and data tracking capabilities of their quality inspection systems at scale.
• Arda Therapeutics — Arda Therapeutics is a biotechnology company taking aim at chronic diseases and aging by eliminating the pathogenic cells that drive these conditions. Their approach starts by using single-cell data to identify pathogenic cells and specific markers to target them. They then design therapies to eliminate these - and only these - cells.Arda wasfounded in 2021 in the San Francisco Bay Area, CA.

Portfolio highlights

• Hermeus — Hermeus is developing hypersonic aircraft to connect the world faster than ever before.
• WorkMotion — WorkMotion offers Global HR Solutions to help companies navigate the New Ways of Working. Solutions fully compliant.
• Savvy — Savvy is a software development company that engages in cybersecurity.

Portfolio highlights

• Latus Bio — Latus Bio focuses on developing innovative gene therapy candidates using precision delivery to enhance the lives of patients. Latus identified proprietary AAV capsids for clinical use. The company plans to administer low doses of its product candidates, aiming to improve clinical safety and manufacturing.
• Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi
• Vittoria Biotherapeutics — Vittoria Biotherapeutics develops gene-edited cell therapies.  they provide next-generation, paradigm-shifting T-cell therapeutics that address unmet medical needs. Senza5 Technology from viTToria improves the efficacy, safety, and utility of cell-based treatments in preclinical settings.

Portfolio highlights

• Bigscreen — Founded by Darshan Shankar in 2014, Bigscreen is a venture-backed startup creating an immersive virtual reality platform that aims to revolutionize the way people work, play, hangout, and collaborate.Use cases of Bigscreen include both entertainment and productivity. Users love using Bigscreen as a "VR movie theater" to watch movies andTV shows. It's also used to play videogames, browse the web, and hangout with friends. It's can also be used for productivity as a tool for remote teams to collaborate together in virtual offices.Since the beta launch in March 2016, Bigscreen has become one of the most popular and highest rated VR apps on the Oculus Store and has an incredible 93% positive rating on Steam. Power users spend 20-30 hours per week in Bigscreen, making it one of the most widely used "killer apps" in the industry.Bigscreen is now the most popular non-gaming VR application in the world.Bigscreen is a fully distributed remote company with employees based around the world in the US & UK.
• Dapper Labs — Dapper Labs uses the power of play to deliver blockchain-based experiences that are made for you and ready for the real world.
• The Believer Company — Join the journey We are building a world-class team to serve players for years to come. If you believe in games, we believe in you.

Portfolio highlights

• Exonics Therapeutics — Exonics’ laboratory has demonstrated the ability to use adeno-associated virus (AAV) to deliver a payload based on CRISPR/Cas9 technology that can identify and correct exon mutations that prevent the production of dystrophin, a protein that helps stabilize and protect muscle fibers.
• Revolution Medicines — Revolution Medicines is developing new therapies through an innovative approach that harnesses the complex chemicals of life by reconfiguring natural substances into best-in-class medicines.REVOLUTION Medicines builds upon the vision of the company’s founder, Martin D. Burke, M.D., Ph.D., professor of chemistry, University of Illinois atUrbana-Champaign, and Early Career Scientist of the Howard Hughes Medical Institute, who invented a transformative method for synthesizing original compounds that are pharmaceutically optimized analogues of complex natural products. REVOLUTION Medicines has entered into an exclusive license agreement with the University of Illinois to practice and expand this technology.REVOLUTION Medicines’ approach is a rapid, standardized and powerful process for assembling simple “chemical building blocks” into refined natural product-like structures. These optimized compounds have significant potential as best-in-class drug candidates.
• Constellation Pharmaceuticals — Constellation Pharmaceuticals is the first biopharmaceutical company dedicated to the development of novel therapeutics in the emerging field of Epigenetics, a new field of science which is focused on selective regulators of epigenetic function, which are critical to controlling gene expression.

Portfolio highlights

• Smarterer — Individuals and Fortune 500 companies use Smarterer to help close the gap between the skills they have and the skills they need. Their dynamic assessment engine leverages the freshest crowdsourced tests around, to rapidly pinpoint skill level with a credible score. In November 2014, Pluralsight, the global leader in online learning for serioussoftware developers, IT specialists and creative technologists, acquired Smarterer. As the world's largest curated e-learning library for professionals, the company offers instant access to more than 3,500 courses authored by top experts. Smarterer will continue to power crowdsourced assessments for freelancer marketplaces, e-learning providers and enterprise companies anywhere people need to prove their skills to connect with professional opportunities. The Smarterer community has answered over 56 million during 1.7 million test sessions, across hundreds of tests.
• Zest — Give your shoppers the swiftest gifting experience in ecommerce. With Zest, shoppers on your site can send a gift to anybody, anywhere with just a link.
• EpiBiologics — EpiBiologics develops first-in-class antibody based targeted therapies against membrane and extracellular proteins that drive underlying disease biology.

Portfolio highlights

• Elegen — Skip cloning with the only entirely cell-free DNA synthesis provider. Sequences up to 7 kb. Error rates as low as 1:70,000/bp. Manufactured in USA, NGS-verified and shipped globally in as few business days.
• Checkerspot — A biology-driven platform creating specialized lipids from fermentation
• Tierra Biosciences — Speed, scale and simplicity with protein synthesis on-demand. Discover your portal to thousands of custom proteins. Get testable material with a single input.

Portfolio highlights

• Splice Bio — Splice Bio is a gene therapy company based on technology developed in the Muir Lab at Princeton University. The company is developing novel gene therapies based on its proprietary intein platform technology to treat patients that suffer from incurable genetic diseases. The company’s platform has the potential to address two existing limitations ofadeno-associated viruses (AAVs), both by increasing the size of the cargo gene that can be delivered and by expanding the range of tissues that can be targeted.
• Bionano Genomics — Discover how Bionano is striving to elevate health and wellness for all through optical genome mapping (OGM) solutions that transform the way the world sees the genome.
• LOQUS23 THERAPEUTICS — LoQus23 is a DDF-formed company focussing on targeting DNA damage repair pathways to treat Huntington’s disease and other triplet repeat diseases.

Portfolio highlights

• Clarifai — Clarifai is the leading Machine Learning, Computer Vision, NLP Platform. Label, train, deploy models on one AI platform for developers & data scientists.
• Primer — Primer makes powerful mission-ready AI software designed to work in your environment, on your data. We help national security teams sift through massive unstructured data sets to find the needle in the haystack, understand and visualize their data, and act collaboratively. Our mission is to empower decisions that can be defended, and acted upon confidently.
• Impulse Space — Economical and nimble last-mile space payload delivery

Portfolio highlights

• NorthPage — NorthPage provides a cloud-based digital marketing optimization platform that enables frictionless performance benchmarking, competitive analysis, and best-practice guidance for enterprise marketing organizations. Its solutions enable optimization of Websites, e-commerce sites, mobile marketing, social media, search engine marketing, contentmarketing, and e-retail programs. The company serves retail, financial services, consumer product, pharmaceutical, and technology companies. NorthPage Inc. was founded in 2007 and is based in Southbury, Connecticut.
• IntelliBoard — The IntelliBoard Learning Analytics Platform helps you retain students, increase their engagement, and manage compliance.
• Mobile Sense — The traditional diagnostic market is being transformed by advances in high performance wearables. This seismic shift led by consumer products which are uncovering new patients who previously went undetected, but still require a detailed diagnosis. Mobile Sense™ is building foundational technology that enables this transformation throughoff-the-chest wearables for long term management of cardiac arrhythmias. Developed over 7 years with $4.2M in grant funding and $1.3M in seed funding, Mobile Sense™ has a platform for differentiated wearables. Our embedded algorithms coupled with non-adhesive, wireless & waterproof sensors provides high fidelity continuous ECG and PPG recordings. The automatic monitoring provides 24/7, 365 days/yr continuous detection and classification of dangerous heart arrhythmias.

Portfolio highlights

• Farcast — Unlocking satellite internet capacity through user terminal innovation
• Solugen — Solugen's mission is to decarbonize the chemicals industry. Solugen combines synthetic biology with metal catalysis to make carbon negative chemicals at scale.Solugen's patented approach takes advantage of bio-inspired reactions to use plant material as a low-cost feedstock to produce novel products cost-competitive with thecompetition.
• Valence Discovery — Empowering drug discovery scientists with the latest advances in AI-enabled drug design

Portfolio highlights

• ZwitterCo — ZwitterCo is revolutionizing water & wastewater treatment with cutting-edge membrane technology, along with providing sustainable, high-efficiency solutions.
• Jupiter Intelligence — The Trusted Leader in Climate Risk Analytics. Learn about our best-in-science solutions.
• Relation Therapeutics — Relation uses machine learning to develop drugs for pressing unmet need.

Portfolio highlights

• Umlaut.Bio — Decoding RNA modifications to revolutionize cancer and inflammation treatment. Umlaut.bio GmbH is a pioneering biotech company focused on developing first-in-biology therapeutic molecules to modify tRNA and target cancers and inflammatory diseases.
• Velocity Bio — Velocity Bio is a Stanford University spinout developing high-throughput platforms capable of selectivity-first allosteric drug discovery for under-drugged human enzymes implicated in devastating diseases.
• Bullseye Biosciences — Bullseye Biosciences is a therapeutics discovery company revolutionizing drug development through robotics and evolution. Our platform operationalizes cutting-edge directed evolution technology by incorporating automation and Next Generation Sequencing. By targeting challenging drivers of human dise

Portfolio highlights

• Paxton — Regulatory Intelligence, with the speed of Generative AI.
• Limbic — Limbic creates neuroscience of emotion packaged for developers. With just a few lines of code, anyone can make their app emotionally intelligent. Use the SDK to build products that interact with your user as naturally as interactions between two humans.
• Sharper Sense — Neuromodulation for Clear Senses

Portfolio highlights

• GenomSys — Keep your genomic data safe and run analyses whenever you like. Discover how GenomSys is democratizing genomic analysis.
• Lightform — Lightform LFC Kit and LF2+ AR projector enable you to create light and sound experiences with sound-reactive projection mapping. Lightform brings projection mapping in reach for visual artists, designers, and other creatives.
• TripleBlind — TripleBlind unlocks the estimated 105 petabytes of data stored by enterprises today that are inaccessible and not commercialized due to privacy concerns, operational complexity and regulation. The company’s patented breakthroughs in advanced mathematics enable organizations to privately share larger and more diverse data sets. Many high-valueapplications apply, such as innovating enhanced algorithms for medical diagnoses and improving anti-fraud initiatives for financial services. TripleBlind is the only technology that enables enterprises to rapidly commercialize data while maintaining compute performance; enabling all types of analysis on all data types, such as PII, PHI, genomic data, images, and confidential financial records. At the same time, the solution automatically enforces all international and regional data privacy standards including HIPAA, GDPR, PDPA and CCPA.TripleBlind is superior to existing solutions such as homomorphic encryption (slows compute performance), secure enclaves (siloes data), tokenization/masking/hashing and differential privacy (reduces accuracy), synthetic data (not real data), federated learning (limited use for algorithms), confidential computing (requires data centralization) and blockchain (not interoperable). Innovators such as Accenture, the Mayo Clinic and Snowflake trust TripleBlind to protect sensitive data. Please contact us for an overview, live demo or a one-hour, hands-on workshop.

Portfolio highlights

• Ribometrix — The Next Frontier of Drug Discovery
• Contego Medical — Better Outcomes. Simplified. Neurovascular Peripheral Vascular Neurovascular
• G1 Therapeutics — G1 Therapeutics is a clinical-stage company developing novel cancer therapies. It was founded in 2008 by Drs. Norman Sharpless and Kwok-Kin Wong to capitalize on discoveries made and patented by Dr. Sharpless’ lab at the University of North Carolina at Chapel Hill, and subsequently licensed to G1 Therapeutics. Trilaciclib is an investigationaltherapy designed to improve outcomes for people with cancer who are treated with chemotherapy. G1 is also advancing rintodestrant, a potential best-in-class oral selective estrogen receptor degrader, or SERD, for the treatment of ER+ breast cancer.

Portfolio highlights

• HilleVax — HilleVax is a biopharmaceutical company that focuses on the development and commercialization of novel vaccines. HilleVax was founded in 2021 and was headquartered in Boston, Massachusetts.
• Zavante Therapeutics — Zavante is a clinical-stage biopharmaceutical company focused on developing novel therapies to improve the outcomes of hospitalized patients.
• Alpine Immune Sciences — Vertex Pharmaceuticals invests in scientific innovation to create transformative medicines for people with serious diseases.

Portfolio highlights

• Culture Biosciences — Culture Biosciences develops automated bio-reactor that helps biotech companies optimize their manufacturing processes and brings products to market faster. The company also builds automated tools for fermentation. It has a digital bio-manufacturing platform to enable scientists to run, monitor, and analyze bio-reactors faster than traditionalapproaches by robotic sample handling and cloud data monitoring and analysis.Culture Biosciences was founded in 2016 and is headquartered in San Francisco, California.
• Scipher Medicine — At Scipher Medicine, we are committed to transforming the way providers prescribe drugs, as well as the way manufacturers, develop new drugs. We have built a molecular map of all protein interactions that identifies genomic signatures and links those to disease and predictive treatment outcomes. Using a simple blood sample to analyze RNA, we canpredict if a patient is likely to respond to a targeted therapy before therapy is prescribed. This insight allows patients to start the most effective therapy from day one. For our first commercial product, we have developed PrismRA®, a first-of-its-kind blood test that can predict which patients with rheumatoid arthritis are less likely to respond to TNFi therapies such as Humira® and Enbrel® so that such patients can go on alternative approved drugs.We also used a different one for the ACO Payer Summit, I’ve provided that as well: Scipher Medicine is building the future of patient treatment. Most patients who are prescribed blockbuster therapies today don't respond to treatment, costing the healthcare industry billions in wasted drugs while patients continue to suffer. Scipher's platform identifies which drug will work based on the patient's fundamental disease biology, and not based on symptoms, disease classification, or medical bias. A routine blood test predicts which drug he/she will respond to, with our first product focusing on rheumatoid arthritis, ensuring that the most optimal treatment is prescribed from day one. The molecular data generated by our tests is then used to fuel novel target discovery to address a clear unmet medical need in patients who do not respond to any existing therapy.
• Sound Agriculture — Discover Sound Agriculture, an innovative agriculture company harnessing nature-based solutions that enhance resilience and sustainability.

Portfolio highlights

• Invitae — Invitae and Labcorp together offer advanced genetic testing that can be easily integrated into medical practices. Improve patient care with meaningful insights based on DNA.
• Vera Therapeutics — Vera Therapeutics is a biotechnology company developing innovative biologic therapeutics with transformative clinical potential. The company's gene-editing technology can potentially cure patients with sickle cell disease, cystic fibrosis, and other devastating genetic disorders, enabling physicians to improve gene detection and regulation.
• Aeovian Pharmaceuticals — Aeovian is a San Francisco based biopharmaceutical company developing novel and highly selective therapeutics modulating mTORC1 pathway.

Portfolio highlights

• Neuronetics — Antidepressant medications don't work for everyone. If drugs haven't worked for you, learn about NeuroStar - safe, effective, lasting TMS therapy for depression.
• Pyxis Oncology — Charting a course to therapeutics for difficult-to-treat cancers.
• Triana Biomedicines — Triana Biomedicines is building the leading molecular glue discovery platform to regulate disease targets that are difficult to address with any other modality. Triana’s drug discovery engine is powered by high- resolution structural insights, state-of-the-art in silico tools, and bespoke chemical libraries. The research team has validated thebest-in-class platform and initiated multiple programs across different disease areas.

Portfolio highlights

• OxCan — Enabling curative cancer treatment through early detection
• Wyndly — Retrain your allergies through sublingual (under-the-tongue) treatment plans. Virtual appointments. Treatment delivered. Get started after your first consult with a board-certified doctor for $49.99.
• Foresight Diagnostics — We develop innovative diagnostics to advance decision-making in oncology drug development and patient care.

Portfolio highlights

• AlloCure — AlloCure is a biotechnology company, develops cell therapies for the treatment of various kidney diseases, organ transplants, and multi-organ injuries. It offers biological therapeutics for acute kidney injuries. AlloCure is based in Burlington, Massachusetts. It has operations in Salt Lake City, Utah, and Hamburg, Germany.The company isdedicated to the development of off-the-shelf biological therapies to treat serious and debilitating diseases that afflict millions of people around the world. AlloCure's unique technology uses processed cells derived from human bone marrow to treat a wide variety of diseases. AlloCure was founded on the unique and proprietary technology developed by Dr. Christof Westenfelder and Dr. Axel Zander. Westenfelder and Zander are world-renowned scientists who have dedicated their careers to developing effective therapies for kidney disease. AlloCure has operations in Salt Lake City Utah and Hamburg Germany.
• PTC Therapeutics — Translating Science. Transforming Lives.
• Freeline — A leading biotechnology company focused on innovative liver directed gene therapies for bleeding disorders and other debilitating, chronic diseases

Portfolio highlights

• Ousia Pharma — Ousia Pharma is paving the way for novel therapeutic strategies using peptide-drug-conjugates
• Andrew Alliance — OneLab is laboratory software to design and execute liquid handling protocols. Pipette+ for manual liquid handling pipetting and Andrew+ the pipetting robot
• NRG Therapeutics — energizing drug discovery in neurodegenerative diseases.

Portfolio highlights

• Citrea — Bitcoin's First ZK Rollup
• Lagrange Labs — Seamlessly interact between chains with cryptographically secured state proofs, not opaque intermediaries.
• Workstream — Workstream is an automated hiring platform that helps companies employing hourly workers. The platform helped Jamba, Chick-fil-A, McDonald's, Dunkin', Applebee's, Auntie Anne's, Cinnabon to increase their bottom line and cost savings.Workstream was founded in 2017 and is headquartered in San Francisco, California, UnitedStates.

Portfolio highlights

• Zylö Therapeutics — Patented technology that enables, for topicals, sustained release, increased druggability, a Patchless Patch concept, and enhanced targeting of pores and follicles
• Xeno Biosciences — Xeno Biosciences operates as a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic diseases. Lead program, XEN-101, is a first-in-class, oral formulation designed to shift the gut microbiome to the weight-loss associated state induced by Roux-en-Y Gastric Bypass (RYGB) surgery.It wasfounded in 2015 and is headquartered in Somerville, Massachusetts.
• Astrocyte Pharmaceuticals — Astrocyte Pharmaceuticals Inc. is a privately held drug development company dedicated to accelerating the recovery and well-being of brain injury patients. The company is committed to proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury resulting from stroke,TBI, concussion, and neurodegenerative disorders such as Alzheimer’s disease.

Portfolio highlights

• ATDev — ATDev provides assistive technology and medical device solutions.
• Journey Live — Journey is shifting the way modern companies prioritize mental health. Our proactive, inclusive tools engage every employee, every day.
• Trio Pharmaceuticals — Trio Pharmaceuticals is a cancer therapeutics company that develops dual-action drugs for immunogenic tumors. These drugs directly stop tumor growth and selectively stop immunosuppression in the tumor without targeting the current immune checkpoint pathways. The company was founded in 2018 and is headquartered in San Diego, California.

Portfolio highlights

• Infinity Bio — Learn how Infinity Bio's antibody profiling services can detail the reactome in your samples.
• Predicta Biosciences — Our blood-based approach unlocks true precision medicine.
• Lightcast Discovery — Flexible control over droplet number, occupancy, location and movement. Enabling efficient, multi-step workflows with unprecedented flexibility.

Portfolio highlights

• Terrana Biosciences — Terrana's innovative technological platform enables resilient agriculture in a fast changing world by providing RNA-based plant health solutions.
• Quotient Therapeutics — Discover how Quotient is pioneering a new field of genetics with somatic genomics to unveil a universe of genetic information and develop new therapies.
• Ampersand Biomedicines — Ampersand is enabling potent mechanisms to treat disease by creating and programming therapeutics that are more efficacious, without compromising on safety or tolerability.

Portfolio highlights

• Epic Sciences — Epic Sciences develops clinical solutions that accelerate drug development and guided therapy across cancer drug indications. Epic's new AR-V7 CTC liquid biopsy test is the first clinically proven predictive test for metastatic castration-resistant prostate cancer.
• Antios Therapeutics — This is an example page. It's different from a blog post because it will stay in one place and will show up in your site navigation (in most themes). Most people start with an About page that introduces them to potential site visitors. It might say something like this: Hi there! I'm a bike messenger
• Fractyl Health — Fractyl Health develops innovative medical device solutions for the treatment of chronic diseases. The growing product pipeline leverages our minimally invasive procedural therapy, Revita DMR (duodenal mucosal resurfacing), which is designed to rejuvenate the lining of the duodenum and improve patient health. They envision a world with bettersolutions to chronic diseases through the use of less invasive, device-based therapies that will lessen the burden on patients, physicians, and payers.Fractyl Health aims to bring curative therapies to the large populations of patients with metabolic disease.

Portfolio highlights

• Knowde — knowde is the online marketing platform dedicated to chemicals and ingredients. They make it easy to connect with customers, online. Use knowde Pages to get your products noticed every time a customer searches on any search engine. Build your knowde Page in an hour and get started for free.
• Astranis — Four billion people still have no internet access. Astranis is here to change that. We're making small satellites for geostationary orbit, recently signed a contract to triple the satellite internet capacity of Alaska, and raised our Series A from Andreessen Horowitz.
• Shield Bio — At Shield, we’re ensuring that antibiotic resistance doesn’t become more deadly than cancer.In 2050 more people will be dying of antibiotic resistant pathogens than cancer. Infections that were once treatable with a simple oral antibiotics are now requiring complex, painful treatments and resulting in serious health complications for patients.Gonorrhea is one such infection, having become resistant to over 10 different antibiotics, they have only one treatment that is still effective and resistance to this has already begun to emerge. With 820,000 new infections every year in the US, antibiotic resistance will spread quickly, which is why the CDC has resistant gonorrhea at an urgent threat level, the highest level available.Shield's novel genomic testing platform enables STI clinics to identify the antibiotic resistant strains of gonorrhea and other pathogens that their patients have, so they can select the correct antibiotics and halt the spread of antibiotic resistance.

Portfolio highlights

• Feldan Therapeutics — Feldan Therapeutics has developed a patented peptide-based technology platform, the Feldan Shuttle, which enables fast and safe intracellular delivery. The company's mission is to develop leading-edge therapeutic applications based on its proprietary platform, as demonstrated by its current pipeline of clinical programs taking advantage of theunique characteristics of the Shuttle.
• Nkarta Therapeutics — Nkarta seeks to improve upon the efficacy of cell therapy, making it more potent, better tolerated and more rapidly available to a broad population of patients with a variety of hematologic and solid tumor malignancies.While T-cell therapy, often known as CAR-T, has proven successful in certain cancer indications, its promise has been limited toa few hematologic malignancies and the side effects can be severe. Natural Killer cells are the immune system’s first responders against diseases and pathogens. Unlike T cells, they have an inherent ability to target tumor cells without genetic alteration, and therefore hold significant promise in the development of potent therapies that can be used more readily for diverse tumor types. Nkarta’s differentiated cell therapy approach is designed to boost and enhance the inherent power of Natural Killer cells to target and destroy tumor cells, while also offering a better tolerated safety profile.
• Mindset Medical — Mindset Medical is a Health Care Company that develops a platform for clinical information. Through their platform physicians will understand patient pain, saves time for providers and patients, they eliminate paper and redundant forms, and allows providers more time for patients. Mindset Medical was founded in 2016 in Phoenix, Arizona.

Portfolio highlights

• Turning Point Therapeutics — The Investor Relations website contains information about Turning Point Therapeutics, Inc.'s business for stockholders, potential investors, and financial analysts.
• Nkarta Therapeutics — Nkarta seeks to improve upon the efficacy of cell therapy, making it more potent, better tolerated and more rapidly available to a broad population of patients with a variety of hematologic and solid tumor malignancies.While T-cell therapy, often known as CAR-T, has proven successful in certain cancer indications, its promise has been limited toa few hematologic malignancies and the side effects can be severe. Natural Killer cells are the immune system’s first responders against diseases and pathogens. Unlike T cells, they have an inherent ability to target tumor cells without genetic alteration, and therefore hold significant promise in the development of potent therapies that can be used more readily for diverse tumor types. Nkarta’s differentiated cell therapy approach is designed to boost and enhance the inherent power of Natural Killer cells to target and destroy tumor cells, while also offering a better tolerated safety profile.
• River Vision Development — River Vision Development develops RV001, a protein therapy for the treatment of Graves’ Orbitopathy (GO). River Vision Development was founded in 2011 and is based in New York, New York.

Portfolio highlights

• Phase — Phase provides 3D-printing medical devices for microfluidics. Phase’s proprietary platform enables PDMS (Sylgard 184) to be 3D printed at a scale and resolution that was previously unattainable.
• QATCH Technologies — Get the most out of a drop
• Atlantic Fish Company — Atlantic Fish Co is a cultivated seafood company using cellular agriculture to bring the world sustainable delicious seafood.

Portfolio highlights

• Passage Bio — Passage Bio, a genetic medicines company, is changing the future of CNS disorders and transforming the lives of patients and their families.
• Avistone Pharmaceuticals — Avistone Pharmaceuticals is a clinical-stage biotechnology company focused on precision oncology therapeutics.
• ALX Oncology — ALX Oncology is a preclinical stage biotechnology company developing innovative immuno-oncology therapies for cancer. It is an independent, private biotechnology company.The founding of Alexo Therapeutics was based upon technology invented by Aaron Ring, K. Christopher Garcia, Kipp Weiskopf, Aron Levin, and Irving Weissman at Stanford University.This discovery involves soluble versions of signal regulatory protein-α (SIRPα) that have been engineered to bind CD47 with significantly greater affinity than natural SIRPα.1.

Portfolio highlights

• Cabaletta Bio — Cabaletta Bio discovers and develops targeted cell therapy product candidates to potentially cure patients with autoimmune diseases. Learn about our CAAR T cell products.
• Alchemab Therapeutics — Alchemab Therapeutics is developing natural protective antibodies designed to keep people free of hard-to-treat diseases. They are building their transformative engine to identify novel drug targets and develop a broad pipeline of novel antibody therapeutics for hard-to-treat cancers, neurodegenerative conditions, and infectious diseases.
• United States Fund For Unicef — United States Fund For Unicef helps save and protect the world's most vulnerable children.