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Top 50 Health Care VC Funds & Investors in United States (September 2026)

The most active venture capital funds investing in United States Health Care startups. This investor list is updated monthly from the Shizune investor database, ranked by number of investments in United States Health Care startup companies. Find investors to raise a Seed, Series A or Series B round with Shizune.
Investor Relevant Deals Geography Stage Focus Round Size
Alumni Ventures
VC Fund
328 United States, United Kingdom, Canada Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $850k–$75M
Right Side Capital Management
VC Fund
310 United States, Canada, United Kingdom Seed, Pre-Seed, Convertible Note Software, SaaS, Health Care $50k–$1.8M
Everywhere Ventures
VC Fund
231 United States, Australia, India Pre-Seed, Seed, Series A Software, Health Care, FinTech $250k–$20M
General Catalyst
VC Fund
201 United States, United Kingdom, India Series A, Seed, Series B Software, Artificial Intelligence, Health Care $1.7M–$123M
Gaingels
VC Fund
200 United States, Canada, Mexico Seed, Series A, Series B Software, Health Care, Artificial Intelligence $1M–$100M
StartUp Health
VC Fund
200 United States, Canada, United Kingdom Seed, Pre-Seed Health Care, Wellness, Medical $20k–$4M
ARCH Venture Partners
VC Fund
165 United States, China, United Kingdom Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $8.4M–$230M
Khosla Ventures
VC Fund
163 United States, India, United Kingdom Series A, Series B, Seed Software, Artificial Intelligence, Health Care $1.9M–$100M
New Enterprise Associates
VC Fund
150 United States, India, United Kingdom Series A, Series B, Series C Software, Health Care, Biotechnology $6M–$103M
Liquid 2 Ventures
VC Fund
145 United States, Mexico, Canada Seed, Series A, Pre-Seed Software, Artificial Intelligence, Information Technology $125k–$48M
Innova Memphis
VC Fund
135 United States, Germany, Argentina Seed, Pre-Seed, Convertible Note Health Care, Medical, Medical Device $25k–$1.5M
Andreessen Horowitz
VC Fund
132 United States, United Kingdom, Brazil Series A, Seed, Series B Software, Information Technology, Artificial Intelligence $1.6M–$112M
Google Ventures
VC Fund
130 United States, United Kingdom, Israel Series A, Series B, Seed Software, Health Care, Biotechnology $1.2M–$121M
SOSV
VC Fund
123 United States, India, United Kingdom Seed, Convertible Note, Pre-Seed Biotechnology, Health Care, Software
Alexandria Venture Investments
VC Fund
119 United States, Canada, France Series A, Series B, Seed Biotechnology, Health Care, Therapeutics $2M–$150M
F-Prime
VC Fund
119 United States, United Kingdom, China Series A, Series B, Series C Health Care, Biotechnology, Medical $8M–$150M
OrbiMed
VC Fund
116 United States, China, Israel Series B, Series A, Series C Biotechnology, Health Care, Medical $9.8M–$160M
Polaris Partners
VC Fund
114 United States, Ireland, Singapore Series B, Series A, Series C Biotechnology, Health Care, Medical $4.6M–$105M
Portfolia
VC Fund
114 United States, Canada, Germany Seed, Series A, Series B Health Care, Biotechnology, Software $347k–$51M
SV Angel
VC Fund
112 United States, Canada, United Kingdom Seed, Series A, Series B Software, Artificial Intelligence, Internet $1M–$100M
BoxGroup
VC Fund
110 United States, Mexico, Canada Seed, Series A, Series B Software, Health Care, Artificial Intelligence $1.8M–$90M
Great Oaks Venture Capital
VC Fund
99 United States, Canada, United Kingdom Seed, Series A, Series B Software, E-Commerce, Health Care $850k–$42M
Lux Capital
VC Fund
98 United States, United Kingdom, Canada Series A, Seed, Series B Software, Artificial Intelligence, Health Care $1.8M–$150M
Flybridge
VC Fund
97 United States, Canada, Brazil Seed, Series A, Series B Software, Artificial Intelligence, Information Technology $1M–$35M
First Round Capital
VC Fund
97 United States, Canada, India Seed, Series A, Series B Software, Information Technology, Artificial Intelligence $1.2M–$60M
Connecticut Innovations
VC Fund
97 United States, Israel, Canada Seed, Series A Health Care, Biotechnology, Software $150k–$25M
Atlas Venture
VC Fund
97 United States, United Kingdom, Canada Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $3.6M–$115M
Bossa Invest
VC Fund
96 United States, Brazil, Mexico Seed, Pre-Seed, Venture - Series Unknown Software, Information Technology, Financial Services $49k–$36M
FJ Labs
VC Fund
92 United States, Brazil, United Kingdom Seed, Series A, Series B Software, E-Commerce, Financial Services $1.2M–$65M
8VC
VC Fund
92 United States, United Kingdom, Canada Series A, Seed, Series B Software, Health Care, Artificial Intelligence $2.5M–$175M
Rock Health Capital
VC Fund
92 United States, Denmark Seed, Series A, Series B Health Care, Medical, Software $20k–$63M
TEDCO
VC Fund
92 United States, Canada, Colombia Seed, Grant, Pre-Seed Health Care, Software, Biotechnology $25k–$2.5M
Founders Fund
VC Fund
91 United States, United Kingdom, Germany Series A, Seed, Series B Software, Health Care, Information Technology $1.7M–$100M
Felicis
VC Fund
88 United States, Canada, Germany Series A, Seed, Series B Software, Artificial Intelligence, SaaS $1.5M–$70M
RA Capital Management
VC Fund
88 United States, United Kingdom, Canada Series B, Series C, Post-IPO Equity Biotechnology, Health Care, Therapeutics $27M–$275M
Lightspeed Venture Partners
VC Fund
87 United States, India, Israel Series A, Series B, Seed Software, Information Technology, Artificial Intelligence $2M–$125M
Canaan Partners
VC Fund
84 United States, United Kingdom, Israel Series A, Series B, Series C Software, Biotechnology, Health Care $5.5M–$75M
Slow Ventures
VC Fund
82 United States, United Kingdom, Israel Seed, Series A, Series B Software, Internet, Health Care $1.4M–$75M
Pear VC
VC Fund
81 United States, Brazil, Colombia Seed, Pre-Seed, Series A Software, Artificial Intelligence, Information Technology $250k–$40M
Social Starts
VC Fund
80 United States, Canada, Germany Seed, Series A, Venture - Series Unknown Software, Health Care, Artificial Intelligence $50k–$14M
Third Rock Ventures
VC Fund
80 United States Series A, Series B, Series C Biotechnology, Health Care, Therapeutics $11M–$190M
Versant Ventures
VC Fund
79 United States, Switzerland, Canada Series A, Series B, Series C Biotechnology, Health Care, Medical $5M–$108M
Dreamit Ventures
VC Fund
78 United States, Israel, Canada Seed, Non-Equity Assistance, Convertible Note Health Care, Software, Information Technology $50k–$12M
City Light Capital
VC Fund
78 United States, Canada Seed, Series A, Series B Health Care, Software, Wellness $1.2M–$60M
Soma Capital
VC Fund
78 United States, India, Mexico Seed, Pre-Seed, Series A Software, Artificial Intelligence, FinTech $125k–$35M
Sand Hill Angels
VC Fund
77 United States, Canada, India Seed, Convertible Note, Series A Software, Health Care, Biotechnology $300k–$25M
Rev1 Ventures
VC Fund
77 United States, Germany Seed, Series A Software, Health Care, Information Technology $200k–$18M
Precursor Ventures
VC Fund
77 United States, Canada, United Kingdom Seed, Pre-Seed, Series A Software, Artificial Intelligence, Health Care $120k–$20M
TCA Venture Group
VC Fund
76 United States, Canada, South Africa Seed, Convertible Note, Venture - Series Unknown Health Care, Software, Biotechnology $50k–$8.5M
Village Global
VC Fund
76 United States, United Kingdom, India Seed, Pre-Seed, Series A Software, Artificial Intelligence, Financial Services $250k–$22M
Access all 17547 VC funds in United States Health Care startups.

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Investor list

Alumni Ventures
VC Fund · Manchester, New Hampshire, United States · 328 investments in United States Health Care startups

Access curated startup investment opportunities and diversified venture capital exposure designed for accredited investors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 2701
  • Round size: Seed $850k–$9.9M; Series A $3.5M–$32M; Series B $8M–$75M
  • Lead/follow: 4% lead, 96% follow
  • Last fund: Likely actively investing — fresh fund, raised $90k in 2026

Portfolio highlights

  • QuadSci — Customer Intelligence AI that predicts churn and growth from product telemetry, CRM data and conversational signals.
  • Veda — Veda is the largest vault infrastructure platform in DeFi, enabling institutions to launch and manage onchain financial products at scale.
  • Iambic — Iambic has created a cutting-edge AI-driven platform to tackle the most challenging design problems in drug discovery and address unmet patient need.
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Right Side Capital Management
VC Fund · San Francisco, California, United States · 310 investments in United States Health Care startups

Systematic Pre-Seed Startup Capital

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Investment focus

  • Industry: Software, SaaS, Health Care
  • Stage:Seed, Pre-Seed, Convertible Note
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 1981
  • Round size: Seed $50k–$1.8M; Pre-Seed $50k–$450k; Convertible Note $50k–$400k
  • Lead/follow: 3% lead, 97% follow
  • Last fund: Likely actively investing — fresh fund, raised $55M in 2025

Portfolio highlights

  • tbh — tbh is a developer of a mobile application designed to provide anonymous feedback to friends. The company's mobile application facilitates asking or answering questions, open text fields and invite abuse when combined with anonymity, enabling users to say things without repercussions and feel better about themselves from the positive feedbackon social networks.
  • Vidrovr — Vidrovr develops multimodal computer vision and machine learning systems to index, tag, and understand video. It processes videos with specific domain constraints, such as in sports, government, and media verticals. Its technology enables its users to search an indexed video corpus and retrieve content inside videos and link it to other media likephotos and text.The company Integrates social media to enable direct interactions between multimedia content. Vidrovr was founded in 2016 and is headquartered in New York.
  • TasksMind — Customer Reliability Platform
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Everywhere Ventures
VC Fund · New York, New York, United States · 231 investments in United States Health Care startups

Everywhere Ventures is a global pre-seed venture capital fund for founders, by founders. Click to read Everywhere VC, by Everywhere Ventures, a Substack publication with tens of thousands of subscribers.

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Investment focus

  • Industry: Software, Health Care, FinTech
  • Stage:Pre-Seed, Seed, Series A
  • Geography: United States, Australia, India

Investor stats

  • Total investments: 1303
  • Round size: Seed $1M–$6.5M; Pre-Seed $250k–$2.5M; Series A $6M–$20M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely actively investing — fresh fund, raised $4.4M in 2026

Portfolio highlights

  • Donna — Meet Donna, the AI assistant built for field sales teams. Save time, cut admin, and close more deals with less effort.
  • Keebler Health — AI-Enabled Coding for Medical Billing Teams
  • Neurometric AI — Making Intelligence Free | https://t.co/ZxWxeMBJt2 | https://t.co/W8nlLqYwQi
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General Catalyst
VC Fund · Cambridge, Massachusetts, United States · 201 investments in United States Health Care startups

Investing in powerful, positive change that endures

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 2255
  • Round size: Seed $1.7M–$18M; Series A $6.7M–$75M; Series B $14M–$123M
  • Lead/follow: 46% lead, 54% follow
  • Last fund: Likely actively investing — fund raised in 2026

Portfolio highlights

  • Envoy Global — 25 years. 180+ countries. 2,000+ corporate clients. Envoy combines legal expertise and technology to simplify global immigration management.
  • TaleMonster Games — TaleMonster is a multinational mobile game firm that genuinely wants to provide millions of gamers experiences they won't soon forget. By putting our passion at the center of everything we make, we hope to reinvent what casual in mobile gaming means.
  • Ares Interactive, Inc. — We build player-loved games. Player-first. Built to last.
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Gaingels
VC Fund · New York, New York, United States · 200 investments in United States Health Care startups

Gaingels is a venture investment syndicate in service of the LGBT+ community and its allies, investing in companies with LGBT+ founders and C-suite leaders at all stages of growth, as well as in more established companies resolved on building more inclusive teams, with a global portfolio of 130+ companies and $70M in deployed investment capital todate. The Gaingels network also actively supports its portfolio in identifying and recruiting diverse talent to their C-suite and board leadership teams and fosters a vibrant global community of industry leaders, investors, operators, and entrepreneurs who share a common goal for positive social change through business and successful investments.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Mexico

Investor stats

  • Total investments: 1338
  • Round size: Seed $1M–$8.2M; Series A $5M–$35M; Series B $16M–$100M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely actively investing — fresh fund, raised $140k in 2026

Portfolio highlights

  • Catio — Cloud architecture platform enabling companies to excel with cloud native tech stacks, focused on tech stack evaluation, planning, and evolution, with the help of AI.
  • Epirus — Epirus is a high-growth technology company that develops cutting-edge directed energy systems and power management solutions to transform multiple industries.
  • Multiverse Computing — World leaders in quantum computing for the financial industry. The first quantum & quantum-inspired toolbox for finance.
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StartUp Health
VC Fund · New York, New York, United States · 200 investments in United States Health Care startups

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

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Investment focus

  • Industry: Health Care, Wellness, Medical
  • Stage:Seed, Pre-Seed
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 335
  • Round size: Seed $100k–$4M; Pre-Seed $20k–$854k
  • Lead/follow: 3% lead, 97% follow
  • Last fund: May invest from a new fund soon — raised $31M in 2018

Portfolio highlights

  • AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
  • Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs
  • NEXT Life Sciences — NEXT Life Sciences is developing the revolutionary Plan A™ procedure to bring the only scientifically proven technology in the category - Vasalgel® - to market.
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ARCH Venture Partners
VC Fund · Chicago, Illinois, United States · 165 investments in United States Health Care startups

ARCH Venture Partners provides seed / early stage venture capital for technology firms in information technology, life sciences, and physical sciences

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, China, United Kingdom

Investor stats

  • Total investments: 467
  • Round size: Series A $8.4M–$216M; Series B $15M–$230M; Series C $15M–$167M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: Likely still investing — raised $3B in 2024

Portfolio highlights

  • Synchron — The endovascular brain computer interface.
  • Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.
  • Moonwalk Biosciences — By deeply profiling and targeting the epigenetic code, Moonwalk aims to reprogram cells to their healthy state, fundamentally enabling a new approach to how therapies are discovered and developed.
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Khosla Ventures
VC Fund · Menlo Park, California, United States · 163 investments in United States Health Care startups

Khosla Ventures is a venture capital firm that invests in early- to late-stage companies across sectors like AI, healthcare, sustainability, and consumer technology. It manages multiple funds, focusing on startups with innovative technologies or business models. The firm primarily targets sectors like AI, climate tech, digital health, and medtech,offering strategic support to help build long-lasting companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Series B, Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1441
  • Round size: Seed $1.9M–$25M; Series A $5.5M–$47M; Series B $11M–$100M
  • Lead/follow: 39% lead, 61% follow
  • Last fund: Likely actively investing — fresh fund, raised $31M in 2026

Portfolio highlights

  • Seeo — Daftar akun togel resmi bisa melalui via dana, ovo, gopay, linkaja kami juga menyediakan berbagai link togel terpercaya seperti bo togel hadiah 2d 200rb, bandar togel hadiah 4d 10 juta terpercaya, situs togel resmi dan terpercaya, agen togel terpercaya, daftar bandar togel terbesar dan terpercaya, bandar togel terbesar, situs togel prize 123, bo togel bolak balik dibayar dan banyak lainnya yang kami sediakan untuk pencinta link togel resmi di Indonesia.
  • Anrok — Anrok automates sales tax compliance across your financial stack, so you can grow your SaaS business in any market.
  • Lovable — Build apps, websites, and digital products faster using Lovable's AI-powered platform, no deep coding skills required.
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New Enterprise Associates
VC Fund · Menlo Park, California, United States · 150 investments in United States Health Care startups

Foundational partners to ambitious founders at every stage of company-building.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series A, Series B, Series C
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1995
  • Round size: Series A $6M–$55M; Series B $10M–$90M; Series C $15M–$103M
  • Lead/follow: 38% lead, 62% follow
  • Last fund: Likely still investing — raised $468M in 2024

Portfolio highlights

  • Zyngenia —
  • Radiology Partners — Radiology Partners is the leading radiology practice in the U.S., consisting of a network of of radiology practices serving hospitals and other healthcare facilities across the nation.
  • Sportsrocket — Sportsrocket is a New York-based company working to give sports fans access to live games and events, highlights, and shows. The company works with leading leagues, publishers, and rights-holders, including Major League Soccer, the PGA Tour, Scout Media, and AS Roma, to create and power customized OTT platforms. Incubated by Bedrocket MediaVentures, Sportsrocket's innovative approach is based on a proprietary sports media operating system, that offers an integrated solution for the production, distribution, management, and monetization of sports media across all platforms.
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Liquid 2 Ventures
VC Fund · San Francisco, California, United States · 145 investments in United States Health Care startups

Liquid2 Ventures provides technology startups with seed-stage investments and is based in San Francisco, California. The firm was founded in 2015 by Joe Montana, Mike Miller, and Michael Ma.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Pre-Seed
  • Geography: United States, Mexico, Canada

Investor stats

  • Total investments: 1234
  • Round size: Seed $1.1M–$9.1M; Pre-Seed $125k–$2.7M; Series A $6M–$48M
  • Lead/follow: 1% lead, 99% follow
  • Last fund: Likely actively investing — fresh fund, raised $12M in 2026

Portfolio highlights

  • Albedo — Aerial quality imagery - from space.
  • Vulcan — Frontier AI for government, law, and policy | backed by @ycombinator @generalcatalyst @cubitcapital
  • Attention — Attention is building an AI co-pilot designed to automate repetitive, multi-app desktop tasks.
Show all investments...

Access 48,091 investors

822 industries, 177 countries. Updated daily. Emails and phones included.

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Innova Memphis
VC Fund · Memphis, Tennessee, United States · 135 investments in United States Health Care startups

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

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Investment focus

  • Industry: Health Care, Medical, Medical Device
  • Stage:Seed, Pre-Seed, Convertible Note
  • Geography: United States, Germany, Argentina

Investor stats

  • Total investments: 284
  • Round size: Seed $25k–$1.5M; Pre-Seed $25k–$1.3M; Convertible Note $48k–$1.4M
  • Lead/follow: 26% lead, 74% follow
  • Last fund: Likely still investing — raised $40M in 2023

Portfolio highlights

  • HerdDogg — HerdDogg is a global herd health and data science platform. It is a two-part system that helps ranchers track health and proximity data from their herd. The company's device gathers the data captured by the ear tags and reports it directly to the rancher via an app or web database.
  • Insignum AgTech — Insignum AgTech develops biotech plants that communicate with producers, alerting them to an illness in its early stages.
  • Soiltech Wireless — Soiltech Wireless is a developer of ag-tech solutions to design electronic devices for agricultural professionals. Its product provides real-time data to drive efficiency and optimize quality. It also provides actionable data without installation hassles and creates scalable monitoring solutions for farmers.The company was founded in 2019 and isheadquartered in Rupert, Idaho.
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Andreessen Horowitz
VC Fund · Menlo Park, California, United States · 132 investments in United States Health Care startups

Andreessen Horowitz (a16z) is a venture capital firm in Silicon Valley, California, investing in bold founders, innovators, and entrepreneurs building the future through technology.

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Investment focus

  • Industry: Software, Information Technology, Artificial Intelligence
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Brazil

Investor stats

  • Total investments: 2069
  • Round size: Seed $1.6M–$16M; Series A $9M–$55M; Series B $17M–$112M
  • Lead/follow: 49% lead, 51% follow
  • Last fund: Likely actively investing — fresh fund, raised $1.2B in 2026

Portfolio highlights

  • Radiant — Clean. Portable. Safe. Energy
  • Supersonik — Supersonik provides an AI-powered platform for SaaS companies to offer 24/7 interactive product demos, enabling prospects to explore and personalize demos instantly without scheduling or manual intervention.
  • Socket — Socket fights vulnerabilities and provides visibility, defense-in-depth, and proactive supply chain protection for JavaScript, Python, and Go dependencies.
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Google Ventures
VC Fund · Mountain View, California, United States · 130 investments in United States Health Care startups

GV supports innovative founders moving the world forward.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Series A, Series B, Seed
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 1459
  • Round size: Seed $1.2M–$16M; Series A $6M–$100M; Series B $16M–$121M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: May invest from a new fund soon — raised $100M in 2014

Portfolio highlights

  • SolveAI —
  • Smarterer — Individuals and Fortune 500 companies use Smarterer to help close the gap between the skills they have and the skills they need. Their dynamic assessment engine leverages the freshest crowdsourced tests around, to rapidly pinpoint skill level with a credible score. In November 2014, Pluralsight, the global leader in online learning for serioussoftware developers, IT specialists and creative technologists, acquired Smarterer. As the world's largest curated e-learning library for professionals, the company offers instant access to more than 3,500 courses authored by top experts. Smarterer will continue to power crowdsourced assessments for freelancer marketplaces, e-learning providers and enterprise companies anywhere people need to prove their skills to connect with professional opportunities. The Smarterer community has answered over 56 million during 1.7 million test sessions, across hundreds of tests.
  • Parabilis Medicines — Parabilis Medicines is a biopharmaceutical company in the clinical stage that focuses on developing exceptional medications targeting challenging protein structures previously deemed undruggable. Utilizing more than ten years of exclusive data, innovative laboratory techniques, and algorithms based on AI and physics, the company has introduced anovel category of stabilized, cell-penetrating alpha-helical peptides known as Helicons™. These peptides can modulate intracellular proteins that traditional drug modalities cannot reach.
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SOSV
VC Fund · Princeton, New Jersey, United States · 123 investments in United States Health Care startups, 75 in the past 12 months

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

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Investment focus

  • Industry: Biotechnology, Health Care, Software
  • Stage:Seed, Convertible Note, Pre-Seed
  • Geography: United States, India, United Kingdom

Investor stats

  • Total investments: 1482
  • Lead/follow: no public data

Portfolio highlights

  • MixRift — MIXRIFT - game developers specialized in Mixed Reality
  • unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
  • Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
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Alexandria Venture Investments
VC Fund · Pasadena, California, United States · 119 investments in United States Health Care startups, 18 in the past 12 months

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Seed
  • Geography: United States, Canada, France

Investor stats

  • Total investments: 297
  • Round size: Seed $2M–$30M; Series A $12M–$100M; Series B $25M–$150M
  • Lead/follow: 8% lead, 92% follow

Portfolio highlights

  • Leal Therapeutics — Leal Therapeutics develops novel therapeutics for patients.
  • Vedana Therapeutics — Vedana Therapeutics is a Seattle biotechnology company developing next-generation antibody therapies for migraine prevention.
  • Khartis Therapeutics — Khartis is a drug discovery company developing oral therapies for patients with immune-mediated and chronic diseases. The company focuses on discovering and developing drug candidates intended to address chronic conditions and immune-mediated diseases.
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F-Prime
VC Fund · Cambridge, Massachusetts, United States · 119 investments in United States Health Care startups

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

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Investment focus

  • Industry: Health Care, Biotechnology, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, China

Investor stats

  • Total investments: 534
  • Round size: Series A $8M–$87M; Series B $15M–$112M; Series C $20M–$150M
  • Lead/follow: 25% lead, 75% follow

Portfolio highlights

  • Lemon Cash — Lemon Cash is digital wallet with FIAT and crypto capabilities. End to end digital ecosystem for Latin America.
  • PlasmaGen Biosciences — PlasmaGen BioSciences is an Indian Bio-pharmaceutical organization specializing exclusively in Plasma Protein Therapy.Headquartered in Bangalore- India, PlasmaGen has been making every effort in the domain of Plasma product Industry and has become an Imperative one stop destination for the medical fraternity for most of the plasma products need.They have a basket of plasma products and the widest range of immunoglobulins in India catering to the requisites of various realms viz. Haematology, Oncology, Immunology, Paediatrics, Rheumatology, Dermatology and Neurology.
  • Ultragenyx Pharmaceutical — Ultragenyx is focused on developing first-ever approved treatments for rare and ultrarare diseases and moving the rare disease community forward.
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OrbiMed
VC Fund · New York, New York, United States · 116 investments in United States Health Care startups

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States, China, Israel

Investor stats

  • Total investments: 740
  • Round size: Series A $9.8M–$140M; Series B $24M–$148M; Series C $19M–$160M
  • Lead/follow: 35% lead, 65% follow
  • Last fund: Likely actively investing — fresh fund, raised $192M in 2026

Portfolio highlights

  • Insilico Medicine — Artificial Intelligence for Drug Discovery and Aging Research
  • Star Therapeutics — Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.
  • Affimed — At Affimed, they are committed to improving outcomes for patients with cancer. Their scientific team has been devoted to unlocking the power of the innate immune system for nearly two decades to provide a unqiue approach to fighting cancer. With their unparalleled expertise in innate immunity and innate cell engager-based medicines, they aim toovercome the limitations and challenges faced by current immuno-oncology (I-O) therapies.
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Polaris Partners
VC Fund · Boston, Massachusetts, United States · 114 investments in United States Health Care startups

Polaris Partners invests in healthcare and biotechnology companies. Their healthcare portfolio companies' care delivery models include digital health, consumer-centric businesses, patient-provider solutions, data science, and analytics. Their life sciences and biotechnology portfolio companies focus on molecules and platforms, therapeutics,and genomics.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series B, Series A, Series C
  • Geography: United States, Ireland, Singapore

Investor stats

  • Total investments: 543
  • Round size: Series A $4.6M–$92M; Series B $7M–$100M; Series C $10M–$105M
  • Lead/follow: 27% lead, 73% follow
  • Last fund: Likely actively investing — fresh fund, raised $439M in 2025

Portfolio highlights

  • Aepona — Aepona Ltd. provides application-led products and services to telecommunications operators worldwide. Its Universal Service Platform allows service creation and implementation to be carried out within the service network from underlying network resources. Aepona, Ltd. serves customers in Europe, North America, and South East Asia. The companywas founded in 1999 and is headquartered in Belfast, United Kingdom. Aepona Ltd. is a former subsidiary of ApiON Ltd.
  • Phreesia — Phreesia's patient intake software helps 4,700+ healthcare organizations increase revenue, reduce no-shows and end front-desk chaos. Get a demo today.
  • 1366 Technologies — Solar is a remarkable technology. We make it even better. Our innovation is tandem. Our promise is more power per square meter.
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Portfolia
VC Fund · San Mateo, California, United States · 114 investments in United States Health Care startups

Investing Funds Designed for Women Backing Innovative Companies We Want in the World - For Returns and Impact

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Germany

Investor stats

  • Total investments: 314
  • Round size: Seed $1.2M–$4.3M; Series A $347k–$15M; Series B $5M–$51M
  • Lead/follow: 6% lead, 94% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • Kind Designs — Kind Designs is a trusted 3D Printed seawall contractor in Miami offering custom seawall construction, shoreline protection, erosion control solutions.
  • AEENA Dx — A brilliant shift in disease detection is coming soon. Learn more A brilliant shift in disease detection is coming soon. Learn more
  • Adjuvia Therapeutics — Adjuvia Therapeutics develops orally delivered, BBB-penetrant nanoparticle therapies that carry nature's most potent antioxidants into the brain, CNS, and organs to treat chronic and rare degenerative diseases.
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SV Angel
VC Fund · San Francisco, California, United States · 112 investments in United States Health Care startups

SV Angel is a service organization, investing in founders who share these values. They support entrepreneurs in building lasting companies by assisting at key inflection points and leveraging networks to help them propel their businesses forward.

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Investment focus

  • Industry: Software, Artificial Intelligence, Internet
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 1335
  • Round size: Seed $1M–$11M; Series A $3M–$37M; Series B $8.3M–$100M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely actively investing — fresh fund, raised $430M in 2025

Portfolio highlights

  • Docker — Docker is a platform designed to help developers build, share, and run container applications. We handle the tedious setup, so you can focus on the code.
  • NavigateAI — An AI copilot for every person in the field. NavigateAI upskills and coaches your team, runs real-time quality control, manages the project in the background, and provides expert knowledge, instantly.
  • Vulcan — Frontier AI for government, law, and policy | backed by @ycombinator @generalcatalyst @cubitcapital
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BoxGroup
VC Fund · New York, New York, United States · 110 investments in United States Health Care startups

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Mexico, Canada

Investor stats

  • Total investments: 802
  • Round size: Seed $1.8M–$9.5M; Series A $6M–$32M; Series B $19M–$90M
  • Lead/follow: 5% lead, 95% follow
  • Last fund: Likely actively investing — fresh fund, raised $275M in 2025

Portfolio highlights

  • Vial — Next generation pharma company powered by computationally designed therapeutics and automated trials
  • Clay — Clay's spreadsheet helps you find, enrich and act on people and company data from any source - without a line of code. Get started for free, today.
  • Sora — Connect HR tools, automate tasks, and deliver great employee experiences
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Great Oaks Venture Capital
VC Fund · New York, New York, United States · 99 investments in United States Health Care startups

Great Oaks Venture Capital is a leading early-stage venture capital firm with a mission to support and invest in the most innovative and disruptive startups. Visit our home page to learn more about our portfolio companies, investment approach, and the experienced team behind our success.

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Investment focus

  • Industry: Software, E-Commerce, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 514
  • Round size: Seed $850k–$5.5M; Series A $3.3M–$15M; Series B $6M–$42M
  • Lead/follow: 4% lead, 96% follow
  • Last fund: May invest from a new fund soon — raised $40M in 2013

Portfolio highlights

  • LuminosAI — Automate AI legal reviews with law firm-grade evaluations. Built by lawyers & data scientists for high-risk AI systems. Ship faster with defensible governance.
  • Snapp — Your AI-powered sports teammate. Research odds, get picks, analyze matchups, scout players, and manage fantasy across 24+ sports and leagues.
  • SingleStore — SingleStore is a provider of a database for operational analytics and cloud-native applications. It provides global enterprises with an intelligent database that works on any cloud on-premises or as a service runs transactions and analytics at the same time and lets clients promote their business through analytics and combine semi-structured datainto a consolidated big data platform.
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Lux Capital
VC Fund · New York, New York, United States · 98 investments in United States Health Care startups

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 688
  • Round size: Seed $1.8M–$25M; Series A $7M–$90M; Series B $13M–$150M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely actively investing — fresh fund, raised $10M in 2026

Portfolio highlights

  • Adimab — Premier Human Antibody Discovery and Optimization
  • Toonimo — Toonimo humanize the web user experience with an engaging and personalized step-by-step interactive walkthrough
  • Cajal Neuroscience — Cajal Neuroscience is a drug discovery company focused on neurodegenerative disease.
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Flybridge
VC Fund · Boston, Massachusetts, United States · 97 investments in United States Health Care startups

New York and Boston Based Early-Stage Venture Capital Firm Backing Seed Stage AI Companies. Focused on AI Enablement, Developer Platforms, Agentic Business Applications, and Native AI for Human Ingenuity

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, Brazil

Investor stats

  • Total investments: 917
  • Round size: Seed $1M–$7M; Series A $4.7M–$22M; Series B $3.4M–$35M
  • Lead/follow: 11% lead, 89% follow
  • Last fund: Likely actively investing — fresh fund, raised $100M in 2025

Portfolio highlights

  • BoobyBiome — BoobyBiome harnesses breast milk microbiome science to develop products to improve infant health
  • Restorando — Restorando is an operator of an online restaurant reservation platform used to improve dining out experiences. Its platform helps restaurants to develop new sales channels to promote available tables and increase revenue that enables consumers to efficiently make reservations online.Restorando was established in 2011 and is headquartered inBuenos Aires, Argentina.
  • Dragon Innovation — We help companies who are launching complex products to strategize and execute their manufacturing from prototype through ongoing production
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First Round Capital
VC Fund · San Francisco, California, United States · 97 investments in United States Health Care startups

First Round is a seed-stage venture firm focused on building a vibrant community of technology entrepreneurs and companies.

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Investment focus

  • Industry: Software, Information Technology, Artificial Intelligence
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 930
  • Round size: Seed $1.2M–$9.2M; Series A $2.9M–$25M; Series B $7M–$60M
  • Lead/follow: 25% lead, 75% follow
  • Last fund: May invest from a new fund soon — raised $296M in 2020

Portfolio highlights

  • Actively — A seamless booking assistant for your favorite fitness classes & wellness experiences
  • Arketa — Online and in-person classes, video on-demand, courses and website hosting - all in one platform with arketa.
  • Flatiron Health — Clinicians, researchers and regulators rely on Flatiron technology and evidence to learn faster and power smarter care for every patient.
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Connecticut Innovations
VC Fund · Rocky Hill, Connecticut, United States · 97 investments in United States Health Care startups

At Connecticut Innovations, we see venture capital the way you see your business. Like no one else. We invest in innovative biotech, IT, and other industries.

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Investment focus

  • Industry: Health Care, Biotechnology, Software
  • Stage:Seed, Series A
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 297
  • Round size: Seed $150k–$5.3M; Series A $2.1M–$25M
  • Lead/follow: 31% lead, 69% follow
  • Last fund: Likely still investing — raised $50M in 2023

Portfolio highlights

  • CyVek — CyVek, Inc. engages in the development of a platform technology for measuring analytes in biological samples. The company was incorporated in 2008 and is based in Wallingford, Connecticut.
  • eBrevia — Analyze contracts at scale, extract key data, and identify risk with eBrevia. Draft and redline agreements in Microsoft Word with DraftPro.
  • Axerion Therapeutics — Axerion Therapeutics, Inc. is a private Connecticut-based biotechnology company focused on developing innovative therapeutics for neurological diseases and injuries with significant unmet medical need, including Alzheimer’s disease and spinal cord injury.Axerion was established in New Haven to develop and commercialize intellectual propertylicensed from Dr. Stephen Strittmatter’s laboratory at Yale University. Axerion’s proprietary technology platforms include blockers of ß-amyloid (Aß) oligomers binding to Prion Proteins (PrP) on the cell surface of neurons as a novel therapeutic target for Alzheimer’s disease and Nogo Receptor decoy protein for recovery of neurological function in spinal cord injury and other neurological diseases.
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Atlas Venture
VC Fund · Cambridge, Massachusetts, United States · 97 investments in United States Health Care startups

Atlas Venture is an early-stage venture capital firm that creates and invests in biotech startup companies led by promising entrepreneurs focusing on life sciences innovation. Its seed-led venture creation strategy rigorously selects and focuses investment on compelling opportunities to build scalable businesses and realize value.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 458
  • Round size: Series A $3.6M–$75M; Series B $8M–$115M; Series C $6M–$95M
  • Lead/follow: 29% lead, 71% follow
  • Last fund: Likely actively investing — fresh fund, raised $400M in 2025

Portfolio highlights

  • E Ink — E Ink Corp. is a supplier of electronic paper display (EPD) technologies. Products made with E Ink's electronic ink are designed to possess a paper-like high contrast appearance, ultra-low power consumption, and a thin, light form. E Ink's technology is tailored for many consumer and industrial applications including handheld devices,watches, clocks, and public information and promotional signs.
  • Songbird — DropCatch.com helps you secure expiring domain names.
  • Ethyreal Bio — Ethyreal Bio is an early-stage biotechnology company developing precision, mechanism-driven therapies for thyroid diseases with high unmet medical needs.
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Bossa Invest
VC Fund · São Paulo, Sao Paulo, Brazil · 96 investments in United States Health Care startups, 29 in the past 12 months

Aprenda a Investir em Startups

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Investment focus

  • Industry: Software, Information Technology, Financial Services
  • Stage:Seed, Pre-Seed, Venture - Series Unknown
  • Geography: United States, Brazil, Mexico

Investor stats

  • Total investments: 2084
  • Round size: Seed $176k–$5.8M; Pre-Seed $49k–$2M; Venture - Series Unknown $632k–$36M
  • Lead/follow: 3% lead, 97% follow
  • Last fund: Likely actively investing — fund raised in 2025

Portfolio highlights

  • FFID — FFID develops AI chatbot platform automating customer communication, lead generation, and marketing workflows.
  • Sandwiche — Sandwiche creates customizable link in bio pages enabling social media monetization and affiliate marketing management.
  • Ambar Technologies — Ambar is a construction tech company that is focused on addressing the Affordable Housing Challenge. Ambar is a leading construction technology company in Latin America. Tech Company focused on addressing the Affordable Housing Challenge. Ambar integrates the Housing Journey into 4 steps, Design, Supply, Assembly, and Living.
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FJ Labs
VC Fund · New York, New York, United States · 92 investments in United States Health Care startups

FJ Labs is a stage-agnostic investment firm that focuses on marketplaces and consumer facing startups.

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Investment focus

  • Industry: Software, E-Commerce, Financial Services
  • Stage:Seed, Series A, Series B
  • Geography: United States, Brazil, United Kingdom

Investor stats

  • Total investments: 1781
  • Round size: Seed $1.2M–$9.5M; Series A $5M–$30M; Series B $10M–$65M
  • Lead/follow: 3% lead, 97% follow
  • Last fund: May invest from a new fund soon — raised $5.5M in 2016

Portfolio highlights

  • HUNTY — HUNTY is a platform that help people find jobs by connecting them with world class mentors who prepare them for the job search process. And people only pay when they get hired.
  • Lastro — Lastro is building Lais, an autonomous AI worker for real estate agencies, starting in Brazil. Our AI agent initially automated lead engagement and qualification via WhatsApp, helping brokerages boost revenue and improve marketing ROI. In each brokerage, Lais acts as a personalized AI “team member” that engages with leads instantly, searches forproperties and answers common inquiries. Brokerages that have Lais in their teams are growing quickly and reporting up to 60% increases in lead conversion rates.
  • Odyssey — Discover how Odyssey Energy Solutions unblocks bottlenecks in DRE project development. Access diverse financing, procure equipment efficiently, and remotely monitor system performance. Join over 2000 renewable energy companies that use Odyssey to scale. Get in touch today.
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8VC
VC Fund · San Francisco, California, United States · 92 investments in United States Health Care startups

8VC is a technology and life sciences investment firm that partners with founders to develop transformational technologies. The firm focuses on creating long-term economic and societal value through its investments across various sectors, including healthcare and logistics.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 667
  • Round size: Seed $2.5M–$13M; Series A $7.7M–$55M; Series B $17M–$175M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely actively investing — fresh fund, raised $45M in 2026

Portfolio highlights

  • Saronic — Providing the most advanced and capable autonomous vessels in the maritime domain.
  • Lumber — Lumber automates scheduling, time tracking, payroll, and more for building contractors. Discover effortless construction workforce management software today.
  • Flywheel.io — Flywheel is a medical image management system that streamlines imaging data aggregation, harmonization, management and analysis at scale.
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Rock Health Capital
VC Fund · San Francisco, California, United States · 92 investments in United States Health Care startups, 6 in the past 12 months

Rock Health Capital is a full-service seed fund that invests in and supports startups working in digital health. The company invests in entrepreneurs working at the intersection of healthcare and technology. Rock Health Capital is a digital health-focused investment firm.

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Investment focus

  • Industry: Health Care, Medical, Software
  • Stage:Seed, Series A, Series B
  • Geography: United States, Denmark

Investor stats

  • Total investments: 117
  • Round size: Seed $20k–$4.2M; Series A $6M–$25M; Series B $8M–$63M
  • Lead/follow: 6% lead, 94% follow
  • Last fund: Likely still investing — raised $33M in 2022

Portfolio highlights

  • Burst — Make your store FSA/HSA friendly in an afternoon. Flat $100/month, no code, no checkout changes, cancel anytime, no hidden fees.
  • Ours Privacy — Privacy platform and customer data platform for healthcare.
  • Rosarium Health — Rosarium Health is a platform that connects service providers (home contractors and occupational therapists) with customers to execute accessible house assessments and accessible home modifications at a client's primary home, leased property, or company.
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TEDCO
VC Fund · Columbia, Maryland, United States · 92 investments in United States Health Care startups

TEDCO is an independent organization that strives to be Maryland’s lead source for entrepreneurial business assistance and seed funding for the development of startup companies in Maryland’s innovation economy.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Grant, Pre-Seed
  • Geography: United States, Canada, Colombia

Investor stats

  • Total investments: 340
  • Round size: Seed $100k–$2.5M; Grant $54k–$1M; Pre-Seed $25k–$900k
  • Lead/follow: 70% lead, 30% follow

Portfolio highlights

  • AGED Diagnostics — AGE Diagnostics develops diagnostic tools for nonalcoholic steatohepatitis (NASH, liver disease) and fibrosis (liver scarring). AGED tools can simultaneously stage fibrosis and distinguish benign from severe liver disease (liver scarring). This method measures the concentration of target biomarkers (genetic signatures) in circulation using atargeted genomic sequencing assessment. When biomarkers are detected over a specific quantity, liver disease (NASH) and/or fibrosis are diagnosed.
  • Morgan State University — Morgan State University - Maryland's Preeminent Urban Public Research University
  • Rockville Science Center — Rockville Science Center provides opportunities for people to engage in science and engineering activities.
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Founders Fund
VC Fund · San Francisco, California, United States · 91 investments in United States Health Care startups

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Series A, Seed, Series B
  • Geography: United States, United Kingdom, Germany

Investor stats

  • Total investments: 1035
  • Round size: Seed $1.7M–$14M; Series A $5.5M–$50M; Series B $15M–$100M
  • Lead/follow: 33% lead, 67% follow
  • Last fund: Likely actively investing — fresh fund, raised $6B in 2026

Portfolio highlights

  • Ubyx — Ubyx is a clearing system that allows anyone,
  • Numeric — Hundreds of teams streamline reconciliations, organize their close, and leverage AI for flux analysis and reporting with Numeric.
  • Prime Intellect — Prime Intellect democratizes AI development at scale. Our platform makes it easy to find global compute resources and train state-of-the-art models through distributed training across clusters. Collectively own the resulting open AI innovations, from language models to scientific breakthroughs.
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Felicis
VC Fund · Menlo Park, California, United States · 88 investments in United States Health Care startups

Backing founders building iconic companies that transcend boundaries

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Investment focus

  • Industry: Software, Artificial Intelligence, SaaS
  • Stage:Series A, Seed, Series B
  • Geography: United States, Canada, Germany

Investor stats

  • Total investments: 687
  • Round size: Seed $1.5M–$14M; Series A $4.4M–$42M; Series B $10M–$70M
  • Lead/follow: 28% lead, 72% follow
  • Last fund: Likely actively investing — fresh fund, raised $900M in 2025

Portfolio highlights

  • Midi Health — Expert care for women 40+. Made for midlife. Delivered by experienced clinicians. Covered by insurance. Book a visit today.
  • RAPIDFORT — Reduce vulnerability and patch management backlog By 80% in minutes. RAPIDFORT profiles your containerized workloads, auto-remediates your vulnerabilities, and identifies which packages are in use by your workload. All before your workload is deployed in production! You can optionally optimize your workloads and remove known and unknown vulnerabilities by minimizing your software attack surface by 80% thus mitigating Zero-Day exploits and Software Supply Chain attacks.
  • ConductorOne — Govern workforce access, deploy AI agents, and get work done with C1.
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RA Capital Management
VC Fund · Boston, Massachusetts, United States · 88 investments in United States Health Care startups

RA Capital Management is an investment advisor based in Boston specializing in the life-sciences and drug development sectors. The company's team has been investing since 2002 and is comprised of professionals with training in biology, chemistry, and medicine and also has industry and business development experience at the executive and boardlevels. The company invests in companies with promising technologies and products.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series B, Series C, Post-IPO Equity
  • Geography: United States, United Kingdom, Canada

Investor stats

  • Total investments: 572
  • Round size: Series B $27M–$151M; Series C $44M–$182M; Post-IPO Equity $35M–$275M
  • Lead/follow: 35% lead, 65% follow
  • Last fund: Likely actively investing — fresh fund, raised $120M in 2025

Portfolio highlights

  • EvodiaBio — EvodiaBio is a bio-industrial firm that creates natural, sustainable scents for the food and beverage industries. Founded in 2021 and is based in Copenhagen, Capital Region.
  • Windward Bio — Windward Bio is a clinical-stage, drug development company committed to improving outcomes for people living with serious immunological diseases.
  • Kinaset Therapeutics — Kinaset Therapeutics is a therapeutics company that focuses on the advancement of novel drugs in areas of unmet medical needs. The company was founded in 2020 and is headquartered in Medfield, Massachusetts.
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Lightspeed Venture Partners
VC Fund · Menlo Park, California, United States · 87 investments in United States Health Care startups

Lightspeed Venture Partners is a multi-stage venture capital firm focused on accelerating disruptive innovations and trends.

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Investment focus

  • Industry: Software, Information Technology, Artificial Intelligence
  • Stage:Series A, Series B, Seed
  • Geography: United States, India, Israel

Investor stats

  • Total investments: 2378
  • Round size: Seed $2M–$26M; Series A $7M–$85M; Series B $15M–$125M
  • Lead/follow: 40% lead, 60% follow
  • Last fund: Likely actively investing — fresh fund, raised $600M in 2025

Portfolio highlights

  • Brale — One regulated system for stablecoin issuance, custody, payments, and compliance. 75+ programs in production across 45 US jurisdictions. SOC 2 Type II. Book a demo.
  • Tennr — Tennr is a custom AI assistant that accelerates research, answers complex questions, and generates custom reports.
  • Ricursive Intelligence — We develop frontier AI methods to reinvent chip development, collapsing traditional design timelines, closing the loop between AI and the hardware that fuels it, and enabling a Cambrian explosion of custom silicon.
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Canaan Partners
VC Fund · Menlo Park, California, United States · 84 investments in United States Health Care startups

Canaan is an early stage venture capital firm that invests in entrepreneurs with visionary ideas. With $5B under management, a diversified fund and over 190 exits to date, Canaan has invested in some of the world's leading technology and healthcare companies over the past 30 years. Canaan’s focus areas include fintech, enterprise/cloud,marketplaces, frontier tech, biopharma, digital health, and medtech.

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Investment focus

  • Industry: Software, Biotechnology, Health Care
  • Stage:Series A, Series B, Series C
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 772
  • Round size: Series A $5.5M–$45M; Series B $8M–$75M; Series C $8M–$60M
  • Lead/follow: 32% lead, 68% follow
  • Last fund: Likely still investing — raised $100M in 2024

Portfolio highlights

  • withco — Rebuilding main street, one share at a time.
  • Diligent Robotics — We build robots like Moxi that assist hospital staff with routine activities so they can focus on caring for patients.
  • GroundWork — GroundWork delivers Unified Monitoring for Real™ with an open software platform for shockingly easy integrations and customized visualizations of cloud, virtualization, network, application, server, and storage data.GroundWork Monitor is available in free (Core) and subscription versions with support (Enterprise).GroundWork was founded in 2004 andis headquartered in San Francisco, California with partners in Asia Pacific, Europe and South America.
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Slow Ventures
VC Fund · San Francisco, California, United States · 82 investments in United States Health Care startups

Slow Ventures is a venture capital firm that focuses on investing in companies central to the technology industry as well as those operating at the intersection of science, society, and culture. The firm seeks to support innovative ideas and solutions that shape the future across various sectors.

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Investment focus

  • Industry: Software, Internet, Health Care
  • Stage:Seed, Series A, Series B
  • Geography: United States, United Kingdom, Israel

Investor stats

  • Total investments: 585
  • Round size: Seed $1.4M–$7.8M; Series A $6.5M–$25M; Series B $14M–$75M
  • Lead/follow: 15% lead, 85% follow
  • Last fund: Likely actively investing — fresh fund, raised $64M in 2025

Portfolio highlights

  • Opendoor Technologies — Opendoor is the new way to sell your home. Skip the hassle of listing, showings and months of stress, and close on your own timeline. Get a free offer today!
  • Steven.com — The operating system for the creator economy. Connecting creators to resources, platforms, community and technology where trust shifts to individuals.
  • Clouted — Clout Kitchen is THE Virality Engine for brands and creators, designing data-driven viral campaigns with distribution marketing.
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Pear VC
VC Fund · Palo Alto, California, United States · 81 investments in United States Health Care startups, 60 in the past 12 months

Pear VC partners with entrepreneurs from day zero to build category-defining companies.

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Investment focus

  • Industry: Software, Artificial Intelligence, Information Technology
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, Brazil, Colombia

Investor stats

  • Total investments: 511
  • Round size: Seed $1.8M–$9M; Pre-Seed $250k–$3.5M; Series A $8.5M–$40M
  • Lead/follow: 19% lead, 81% follow
  • Last fund: Likely still investing — raised $3.4M in 2024

Portfolio highlights

  • Forus — From PA generation to appeals, enrollments, & pharmacy navigation, Forus handles the end-to-end medication access process. Forus supports every drug, insurance, and pharmacy to help patients get access to life-changing medications.
  • Vals.ai — Private, domain-specific benchmarks in legal, tax, and finance.
  • Piston — Payments technology company for the logistics Industry
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Social Starts
VC Fund · San Francisco, California, United States · 80 investments in United States Health Care startups

Social Starts is a $60M+ venture capital partnership with a uniquely data-driven approach to investing in moment-of-inception and Series A financing rounds.

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Investment focus

  • Industry: Software, Health Care, Artificial Intelligence
  • Stage:Seed, Series A, Venture - Series Unknown
  • Geography: United States, Canada, Germany

Investor stats

  • Total investments: 419
  • Round size: Seed $50k–$3.7M; Series A $3.1M–$14M; Venture - Series Unknown $626k–$6.1M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely still investing — raised $8.9M in 2022

Portfolio highlights

  • Mae Health — Mae is a maternal health platform that connects expectant mothers with critical resources to drive positive pregnancy outcomes.
  • Ruby Bio — Ruby Bio is a biosynthesis platform that can manufacture complex molecules that are biodegradable and non-toxic. Ruby Bio uses naturally occurring yeast as a factory to convert low-cost sugar into high-value products.
  • Funnel — Our revolutionary CRM property management software saves both time and money for agents and owners while making leasing more efficient.
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Third Rock Ventures
VC Fund · Boston, Massachusetts, United States · 80 investments in United States Health Care startups

Third Rock Ventures invests in transformational life science companies that show high growth potential and are well-positioned to make a difference in the marketplace. Third Rock Ventures believes in the companies we start and makes significant initial investments, which are frequently supplemented by strategic collaborations, to help our firmsprogress in life-changing medicines, technologies, and diagnostics.

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Investment focus

  • Industry: Biotechnology, Health Care, Therapeutics
  • Stage:Series A, Series B, Series C
  • Geography: United States

Investor stats

  • Total investments: 176
  • Round size: Series A $19M–$110M; Series B $11M–$190M; Series C $20M–$108M
  • Lead/follow: 47% lead, 53% follow
  • Last fund: Likely still investing — raised $1.1B in 2022

Portfolio highlights

  • Corvia Medical — Corvia Medical is a medical device company, focuses on developing structural heart devices for the treatment of heart failure. The company develops InterAtrial Shunt Device (IASD), a transcatheter device designed to treat diastolic heart failure (DHF), also known as heart failure with preserved ejection fraction (HFpEF). It was founded in 2009and headquartered in Andover, Massachusetts.
  • NinePoint Medical — NinePoint Medical, Inc. is a transformational medical device company developing innovative, real-time, in vivo pathology devices. The company's first goal is to develop a device that enables remote pathology, or telepathology, which would facilitate immediate review of images during diagnostic procedures. This capability could potentiallyprovide physicians with immediately actionable information and eventually allow them to pursue therapeutic remedies at the time of diagnosis. This convergence of access, diagnosis and treatment during one procedure is expected to improve patient experiences and outcomes, improve the efficiency of care and provide important savings to the healthcare system. Headquartered in Cambridge, Mass., NinePoint is backed by Third Rock Ventures and Prospect Venture Partners.
  • Jounce Therapeutics — Concentra is a biosciences company.
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Versant Ventures
VC Fund · Menlo Park, California, United States · 79 investments in United States Health Care startups

Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.

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Investment focus

  • Industry: Biotechnology, Health Care, Medical
  • Stage:Series A, Series B, Series C
  • Geography: United States, Switzerland, Canada

Investor stats

  • Total investments: 324
  • Round size: Series A $5M–$78M; Series B $12M–$105M; Series C $12M–$108M
  • Lead/follow: 30% lead, 70% follow
  • Last fund: Likely still investing — raised $5M in 2024

Portfolio highlights

  • Inari Medical — Inari Medical is a commercial-stage medical device company focused on developing products to treat and transform the lives of patients suffering from venous diseases. They are focused on treating venous thromboembolism and improving the quality of life of patients suffering from this disease by safely and effectively removing blood clots. It hasdeveloped two minimally-invasive, novel catheter-based mechanical thrombectomy devices that are designed to remove large clots from large vessels and eliminate the need for thrombolytic drugs. The ClotTriever system is 510(k)-cleared by the FDA for thrombectomy in the peripheral vessels and is used to treat patients suffering from deep vein thrombosis. The FlowTriever system is 510(k)-cleared by the FDA for the treatment of pulmonary embolism.The company was founded in 2011 and is headquartered in Irvine, California.
  • Gate Bioscience — Gate Bioscience is developing Molecular Gates, a new frontier in protein elimination. Molecular Gates are small molecule drugs that selectively eliminate harmful extracellular proteins at their origin, inside cells, and prevent them from emerging to cause disease.
  • Dayra Therapeutics — Dayra Therapeutics manufactures peptide based medicines.
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Dreamit Ventures
VC Fund · New York, New York, United States · 78 investments in United States Health Care startups

Dreamit Ventures focuses on Healthtech and Securetech startups with revenue or pilots that are ready to scale.

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Investment focus

  • Industry: Health Care, Software, Information Technology
  • Stage:Seed, Non-Equity Assistance, Convertible Note
  • Geography: United States, Israel, Canada

Investor stats

  • Total investments: 334
  • Round size: Seed $200k–$6M; Convertible Note $250k–$12M; Non-Equity Assistance $50k–$50k
  • Lead/follow: 28% lead, 72% follow
  • Last fund: Likely still investing — raised $30M in 2022

Portfolio highlights

  • Aurva — Your AI-powered Data Security Co-pilot. Identify, detect and streamline remediation of internal & external threats in real time.
  • Parse.ly — Parse.ly makes working with data easy for newsrooms and marketers, giving them the insights they need to focus their content strategy and prove ROI.
  • Notehall — Notehall is an online marketplace that allows college students to buy and sell appropriate class materials such as lecture notes, reading notes & study guides Fellow classmates helping them get an edge in their specific classes while student sellers make money doing something they already do anyway.Notehall is active and generating revenueat 54 Universities and continuously expanding its college reach. The company expects to be active in more than 200 Universities by the end of 2011 with more than 750,000 users. Notehall is also expected to grow 400 percent in 2011. They have passed Senate Resolutions at the University of Arizona and Arizona State University making Notehall an official student service at both universities. Notehall is actively building relationships with professors and administration at universities to create a lasting and transparent partnership. The Co-Founders of Notehall were selected as the finalist for the Business Week's 2009 America's Best Young Entrepreneurs.
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City Light Capital
VC Fund · New York, New York, United States · 78 investments in United States Health Care startups

City Light is a venture capital firm that invest in impactful companies in the areas of education, safety and care, and the environment.

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Investment focus

  • Industry: Health Care, Software, Wellness
  • Stage:Seed, Series A, Series B
  • Geography: United States, Canada

Investor stats

  • Total investments: 223
  • Round size: Seed $1.2M–$8M; Series A $4M–$30M; Series B $8.5M–$60M
  • Lead/follow: 7% lead, 93% follow
  • Last fund: May invest from a new fund soon — raised $30M in 2020

Portfolio highlights

  • BoodleBox — BoodleBox is the collaborative AI workspace where humans lead, and AI scales impact. Built for education, enterprise, and individuals. Start for free.
  • Salvo Health — Salvo Health is a digital care team for Irritable Bowel Syndrome (IBS), GERD, SIBO, and other chronic gut health conditions. Sign up today!
  • Xage Security — Secure, manage & transform OT, IT and cloud operations. Deliver zero-trust local access, remote access, and data security.
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Soma Capital
VC Fund · San Francisco, California, United States · 78 investments in United States Health Care startups

Welcome to Soma Capital

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Investment focus

  • Industry: Software, Artificial Intelligence, FinTech
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, India, Mexico

Investor stats

  • Total investments: 1075
  • Round size: Seed $1.2M–$8.5M; Pre-Seed $125k–$3.8M; Series A $5M–$35M
  • Lead/follow: 2% lead, 98% follow
  • Last fund: Likely actively investing — fresh fund, raised $37M in 2026

Portfolio highlights

  • Starcloud — Starcloud is building a network of megawatt-scale data centers in space, scaleable to gigawatt capacity. Falling launch costs allow Starcloud to take advantage of the abundant energy, passive cooling, and high-speed connectivity in space.
  • Cambium — Cambium Carbon is an early stage social enterprise start up focused on implementing systems-level natural climate solutions centered on reforestation and urban wood reuse.
  • Cognition — Cognition develops artificial intelligence systems for software engineering and code automation. The company operates Devin, an AI software engineer that plans, writes, tests, debugs, and deploys code through integrated development workflows. Its platform works with existing development tools and codebases to support engineering tasks acrossapplication development, maintenance, and issue resolution. Cognition also provides tools that assist teams with system design, technical workflows, and collaborative coding processes. The company focuses on AI agents that automate repetitive engineering work while supporting software teams in managing complex development tasks.
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Sand Hill Angels
VC Fund · Mountain View, California, United States · 77 investments in United States Health Care startups

For over two decades, Sand Hill Angels has worked openly and collaboratively with venture capital funds, other angel organizations, and the Bay Area ecosystem that fosters the growth of technology startups.

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Investment focus

  • Industry: Software, Health Care, Biotechnology
  • Stage:Seed, Convertible Note, Series A
  • Geography: United States, Canada, India

Investor stats

  • Total investments: 590
  • Round size: Seed $940k–$6.2M; Series A $1.6M–$20M; Convertible Note $300k–$25M
  • Lead/follow: 2% lead, 98% follow

Portfolio highlights

  • PlusPlus — PlusPlus provides a learning and development SaaS platform for technical professionals. It automates the management of onboarding, workshops, and tech-talks at scale. With PlusPlus, companies attract and develop employees.
  • Clean Power Finance — Clean Power Finance (CPF) is building an online business-to-business marketplace to drive the mass-market adoption of solar. The company connects providers of capital who are committed to investing in residential solar with qualified solar marketers, installers and distributors who need residential solar finance products to differentiate and growtheir businesses. CPF raises 100 percent third-party‐owned project finance funds from institutional investors such as Morgan Stanley and Google, working with the investors to structure and launch the funds with managed risk and return profiles. CPF then markets the funds as solar leases and power purchase agreements (PPAs) to qualified solar professionals, including Paramount Solar and Real Goods Solar (Nasdaq: RSOL), through its licensed online solar sales platform, CPF Tools. CPF Tools is software-as-a-service that simplifies complex sales, quoting, proposal and finance processes and minimizes the “soft costs” of selling solar.CPF’s fund investors earn favorable returns on stable investments on the resulting portfolios of residential distributed generation projects. The company’s solar professional partners gain access to solar leases and power purchase agreements (PPAs) that they can brand and sell to homeowners who want the benefits of solar without the cost and hassle of owning and maintaining a system.CPF manages approximately half a billion dollars of capacity on behalf of fund investors, and supports more than 100 solar professional customers who currently use the CPF Market to sell residential solar finance products to homeowners in CA, CO, HI, MA and NJ. Thousands of solar professionals in all 50 states have extensively used CPF Tools to quote and design solar systems.
  • Magnetic Insight — Magnetic Insight (MI) introduced magnetic particle imaging into the preclinical diagnostic research market enabling quantitative cell tracking, imaging of vascular function, detecting metastatic tumors, visualizing inflammation, CAR-T cell therapies and initial research into regenerative medicine.
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Rev1 Ventures
VC Fund · Columbus, Ohio, United States · 77 investments in United States Health Care startups

Rev1 Ventures is a venture studio in Columbus, Ohio providing tech startups with services, space, mentoring, and connections. Learn more!

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Investment focus

  • Industry: Software, Health Care, Information Technology
  • Stage:Seed, Series A
  • Geography: United States, Germany

Investor stats

  • Total investments: 228
  • Round size: Seed $200k–$3.2M; Series A $1M–$18M
  • Lead/follow: 34% lead, 66% follow
  • Last fund: May invest from a new fund soon — raised $10M in 2021

Portfolio highlights

  • FinOpsly — Maximize your cloud ROI with FinOpsly. Our AI-driven platform empowers organizations with smart cost management, fostering collaboration across teams for over 32% in savings. Simplify your cloud strategy with FinOpsly.
  • InnerActiv — InnerActiv is the leading NextGen eDLP solution, setting new standards in DLP, fraud and insider threat detection.
  • Niobium Microsystems — The encrypted cloud has arrived.
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Precursor Ventures
VC Fund · San Francisco, California, United States · 77 investments in United States Health Care startups

Precursor Ventures is an early-stage venture capital firm focused on pre-seed and seed investments in North America. The firm focuses on investments in B2B and B2C software applications and hardware. Precursor Ventures has adopted the Diversity Term Sheet Rider.

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Investment focus

  • Industry: Software, Artificial Intelligence, Health Care
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, Canada, United Kingdom

Investor stats

  • Total investments: 541
  • Round size: Seed $1.1M–$7M; Pre-Seed $120k–$2.5M; Series A $6M–$20M
  • Lead/follow: 11% lead, 89% follow
  • Last fund: Likely still investing — raised $66M in 2023

Portfolio highlights

  • Scorbit — Scorbit develops a platform for pinball players and pinball machine owners and operators.
  • PodcastAI — Upload one episode. PodcastAI generates transcripts, clips, social posts, a website, and distribution automatically.
  • Xella Health — Women's health testing that goes beyond biomarkers. Xella's multi-omic analysis connects your hormones, metabolism, and more, with concierge clinical care.
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TCA Venture Group
VC Fund · Newport Beach, California, United States · 76 investments in United States Health Care startups

TCA Venture Group is the largest angel investor group in the United States, possessing more than 300 members in five networks in Los Angeles, Orange County, San Diego, Central Coast, and the Inland Empire. Its members provide funding and guidance to more early-stage, high-growth companies in Southern California than any other investment group.Members invest in companies in a wide range of industries, including the life sciences, biotech, IT, services, retail, Internet, financial, software, media, consumer products, and tech startups. TCA as a whole gives companies more than just capital; they also provide counsel, mentoring, and access to an extensive network of potential investors, customers, strategic partners, and management talent. Tech Coast Angels has been ranked by CB Insights to be among the Top 20 Angel Groups in the US; TCA was also ranked as #1 for Network Centrality, meaning we have more connections than anyone! If you are in the game-changing business, we are here to help.

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Investment focus

  • Industry: Health Care, Software, Biotechnology
  • Stage:Seed, Convertible Note, Venture - Series Unknown
  • Geography: United States, Canada, South Africa

Investor stats

  • Total investments: 369
  • Round size: Seed $600k–$3.8M; Convertible Note $50k–$7M; Venture - Series Unknown $400k–$8.5M
  • Lead/follow: 9% lead, 91% follow
  • Last fund: May invest from a new fund soon — last raise in 2015

Portfolio highlights

  • EdgeX — Edokonta builds software that allows hospitals to track mobile equipment, such as IV pumps and ultrasounds. The company was founded in 2018 and based in San Diego, California.
  • Nested Knowledge — Nested Knowledge is designing an interface that allows you to examine the data from a comprehensive literature review on research questions of interest. The interactive, nested features facilitate therapeutic comparisons, assist with research organization, and allow physicians to compare nuances across patient characteristics and outcomes.
  • Major Medical Devices — Major Medical Devices develops next-generation vascular devices for endovascular repair and related surgical procedures.
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Village Global
VC Fund · San Francisco, California, United States · 76 investments in United States Health Care startups, 21 in the past 12 months

Early stage venture capital backed by some of the world's best entrepreneurs.

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Investment focus

  • Industry: Software, Artificial Intelligence, Financial Services
  • Stage:Seed, Pre-Seed, Series A
  • Geography: United States, United Kingdom, India

Investor stats

  • Total investments: 514
  • Round size: Seed $1.5M–$10M; Pre-Seed $250k–$3.5M; Series A $7M–$22M
  • Lead/follow: 20% lead, 80% follow
  • Last fund: May invest from a new fund soon — raised $125M in 2021

Portfolio highlights

  • microagi — Accelerating embodied AGI
  • Legato Audio — Legato Hearing develops stylish glasses with built-in hearing technology, offering a discreet alternative to traditional hearing aids.
  • Cast Insights — Cast Insights is an AI-powered platform that turns global spoken content—TV, radio, podcasts, livestreams—into structured, searchable real-time intelligence for investors, policy teams, strategists, and newsrooms.
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Health Care VC funding in United States at a glance

Stats across 50k deals from 18k investors.

18k
investors
in United States Health Care startups
50k
deals
in United States Health Care startups
$4.4M
median round
in United States Health Care startups
51%
lead investors
lead at least one round
19%
Grant
most common funding stage

Access all 17547 VC funds in United States Health Care startups.

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