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Top 50 Manufacturing VC (Venture Capital) Funds in United States in January 2025

Last updated: Jan 2025 A list of 50 VC (Venture Capital) funds that invest in Manufacturing startups based in United states. We rank investors based on the number of investments they made in Manufacturing companies from United states. We update this investor list every month.

Top 50 Manufacturing VC (Venture Capital) Funds in United States in January 2025

Investor	Manufacturing United States investments
SOSV	61
Lux Capital	31
Alumni Ventures	31
Innova Memphis	28
Khosla Ventures	23
New Enterprise Associates	23
Toyota Ventures	23
Founders Fund	23
Houston Angel Network	22
Clean Energy Ventures	21
Fifty Years	21
Breakthrough Energy Ventures	20
Intel Capital	20
Flybridge	20
Asymmetry Ventures	18
Eclipse Ventures	18
Advantage Capital	18
Prelude Ventures	18
Maine Angels	18
Creative Ventures	16
Right Side Capital Management	16
Congruent Ventures	16
MB Venture Partners	16
Kleiner Perkins	16
Root Ventures	16
The Engine	16
Climate Capital	16
Sequoia Capital	15
Schematic Ventures	15
Threshold	15
Social Capital	14
Draper Associates	14
Cantos	14
DCVC	14
Liquid 2 Ventures	14
Ben Franklin Technology Partners of Northeastern Pennsylvania	14
Good Growth Capital	14
BoxGroup	14
Collaborative Fund	14
The Engine	14
Revolution’s Rise of the Rest Seed Fund	14
Alliance of Angels	13
Lerer Hippeau	13
Bolt	13
Clean Energy Venture Group	13
Wisconsin Investment Partners	12
Safar Partners	12
Gaingels	12
Applied Ventures	12
Launch NY	12

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Investor list

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Lux Capital manages over $5 billion in assets focused on founding, seed, early-stage, and growth investments at the intersection of technology and the sciences. Lux takes an active role in helping entrepreneurs build successful businesses in high-growth sectors. Its investment team has built over 20 companies from scratch. Lux's investmentstrategy ensures portfolio companies are better connected, have a deeper insight, and command industry leadership faster than their competitors.

Investment focus

Software, Health Care, Biotechnology
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Cala Health — Cala Health is a bioelectronic medicine company transforming the standard of care for chronic disease. The company's wearable neuromodulation therapies merge innovations in neuroscience and technology to deliver individualized peripheral nerve stimulation. The first indication for Cala Health's wearable therapy is an essential tremor, adisease experienced by more than seven million people and characterized by severe hand tremors. New therapies are under development in neurology, cardiology, and psychiatry. The company is headquartered in the San Francisco Bay Area and backed by leading investors in both healthcare and technology.
Fiddler AI — Monitor, observe, analyze, and explain your machine learning models in production with Fiddler AI. Maximize ML model performance with our Model Performance Management Platform that simply plugs in.
Bluenote Health — Accelerate innovation with AI built for and trusted by leading life sciences companies.

Alumni Ventures offers diversified venture portfolios to accredited investors into highly competitive deals that individuals typically do not have access to on their own.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Spintly — Integrate the Spintly Smart Access control system with your apps and software, without having to toggle between multiple devices & software.
Torch Dental — Torch Dental develops an all-in-one technology designed to meet dental practices' supply ordering and inventory management needs. Torch Dental simplifies and streamlines the ordering process, allowing dentists to focus on their patients.
Mojave Energy Systems — Mojave the latest in HVAC innovation. Help the Climate. Reduce Energy Use. Improve Indoor Comfort. Perform Reliably. Lower Costs.

Founded in 2007 by the Memphis Bioworks Foundation, Innova is a pre-seed, seed and early-stage investor focused on starting and funding high-growth companies in the Biosciences, Technology and AgBio fields across the state of Tennessee. Innova links capital with great ideas to create groundbreaking products and services.At Innova we invest instart-up companies, help them grow, and then assist them in linking with established corporations for licensing, buy-outs or further investments. We provide the synergy of experienced management, market expertise and venture capital to accelerate the development of new products and services into viable business units that can stand on their own and then take their place with a mature market leader, if desired.Whether an innovation is still on the drawing board or stalled in the market place the Innova staff has the expertise, skills, and experience to envision and create a functioning business unit that is prepared to thrive in the market place. Technical know-how, market-proven staffing, and "just-right" funding assure the greatest chance possible for success.

Investment focus

Health Care, Medical, Medical Device
Seed, Pre-Seed, Convertible Note
United States, Argentina, United Kingdom

Portfolio highlights

Rantizo — Fly more acres, deliver better service. The equipment, tools, and expertise you need to be the grower's first call for drone spray services.
HerdDogg — HerdDogg is passionate about livestock. Its innovative data platform sits at the intersection of agtech, the internet of things, and global food security. Our patented DoggTags and DoggBone, together with our Animal Traceability Platform, help producers make more money from every animal they raise. The HerdDogg system enables animal tracking,welfare monitoring and traceability in an easy-to-use application. For more information, visit herddogg.com.
iYOTAH Solutions — Take your dairy operation to the next level. Our state of the art platform helps you save time, increase efficiencies and profits and unlock new opportunities.

Khosla Ventures invests in companies that are bold, early, and impactful. The firm was started in 2004 by Vinod Khosla, co-founder of Sun Microsystems, to provide venture assistance to entrepreneurs.Khosla Ventures invests in a range of areas including AI, climate, sustainability, enterprise, consumer, fintech, digital health, medtech anddiagnostics, therapeutics, and frontier technology.

Investment focus

Software, Health Care, Artificial Intelligence
Series A, Series B, Seed
United States, India, United Kingdom

Portfolio highlights

Zetwerk — Zetwerk offers high-quality production, globally competitive costs, and unparalleled lead times in every area of manufacturing.
Jones — Jones is a software company that rebuilt liability management for real estate companies who want do less and get more – much more. We are solving one of the most archaic and outdated processes in commercial real estate - insurance certificates. For owners, managers and developers who need to solve insurance compliance for everyone in the valuechain, Jones is the simplest solution ever made.
Basis — Basis operates as an AI platform built specifically for accounting firms.

Foundational partners to ambitious founders at every stage of company-building.

Investment focus

Software, Health Care, Biotechnology
Series B, Series A, Series C
United States, India, China

Portfolio highlights

FIRE1 — FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.
Ouro Medicines — Ouroboros Medicines is a biotechnology company that specializes in immunology and focuses on treating long-term immune-mediated illnesses. The company addresses chronic immune-mediated conditions directly by integrating scientific knowledge, a proven history of progressing cell-depleting treatments through clinical trials, and a strong pipeline.
Orbis Medicines — Orbis Medicines is a novel macrocyclic chemistry and computational platform for high-throughput drug discovery.

Toyota Ventures is a San Francisco Bay Area-based venture capital firm that invests in early-stage startups from around the world. Founded in July 2017, its mission is to discover what’s next for Toyota by helping startups bring disruptive technologies and business models to market quickly. With more than $500 million in assets under management,the firm’s funds include the Toyota Ventures Frontier Fund focused on artificial intelligence, cloud computing, autonomy, mobility, robotics, smart cities, digital health, financial technologies, materials, and energy; and the Toyota Ventures Climate Fund focused on innovative solutions for carbon neutrality.

Investment focus

Artificial Intelligence, Software, Robotics
Series A, Seed, Series B
United States, United Kingdom, Canada

Portfolio highlights

Holyheld — Holyheld is a onchain crypto debit card. The one card for all crypto natives. Get your card, pay from your phone, use your wallet, and pick your crypto.
Ecolectro — Ecolectro is solving the biggest challenges in making Green Hydrogen. Our alkaline ion-exchange membranes and polymers make clean fuel and decarbonize industry.
Starfish Space — Starfish Space: We're developing the first on-demand fleet of versatile and efficient space tugs prepared to service on-orbit satellites. --- Active life extension, debris removal, autonomous transportation

Founders Fund is a San Francisco based venture capital firm investing in companies building revolutionary technologies.

Investment focus

Software, Health Care, Information Technology
Series A, Seed, Series B
United States, United Kingdom, Germany

Portfolio highlights

Radiant — Clean. Portable. Safe. Energy
Network Bio — Network Bio is a clinical and molecular data library enabling precision medicine approaches for common human diseases. Its platform delivers a centralized repository for clinical and molecular data that allows researchers to identify patterns and correlations that can be used to develop new treatments and diagnostic tools.
Crusoe Energy Systems — Crusoe is on a mission to help the oil industry reduce routine flaring of natural gas. They are passionate about creating solutions that benefit the environment, local communities, and energy producers.Crusoe Energy Systems provides oil and gas companies with a fast, low cost and simple solution to natural gas flaring. As the energy industrystruggles with pipeline constraints and increasing regulations around flaring and combusting, Crusoe is here to help. Their service lets operators preserve or regain regulatory compliance, maintain existing production and facilitate future development.

The Houston Angel Network (HAN) is a nonprofit organization dedicated to developing the innovation ecosystem in Houston, Texas by supporting founders and startups with financial resources and mentorship.

Investment focus

Health Care, Software, Information Technology
Seed, Funding Round, Series A
United States, Canada, United Kingdom

Portfolio highlights

Prana Thoracic — A minimally invasive, lung-sparing device that will provide physicians and patients with the certainty they need to move forward with treatment.
Materna Medical — Materna Medical empowers women to protect and restore their pelvic health.
Amplified Sciences — Providing innovative diagnostic tests that enable earlier detection, risk stratification and monitoring of challenging diseases.

Clean Energy Ventures invests in scalable early-stage climate tech startups and clean energy technologies addressing global climate change.

Investment focus

Energy, Manufacturing, Renewable Energy
Seed, Series A, Funding Round
United States, Canada, Israel

Portfolio highlights

Transaera — Transaera is developing a new class of affordable, energy-efficient, sustainable cooling systems and residential air conditioners.
ConnectDER — ConnectDER adapters let anyone connect solar panels or EV chargers to their home at a fraction of the typical time and cost....
Electrified Thermal Solutions — Electrified Thermal Solutions, Inc. is developing the Joule Hive: a new energy storage technology that converts surplus zero-carbon electricity into heat.

WE BACK HEROES using technology to solve the world's biggest problems

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Series B
United States, Germany, Canada

Portfolio highlights

Gridware — Using remote telemetry and edge AI, Gridware wildfire prevention technology powers a grid that is smarter and more reliable than ever before.
Aalo Atomics — Creating abundant and dependable clean energy to power humanity for generations.
Waypoint Bio — Waypoint's proprietary spatial multi-omics platform enables us to solve critical issues around understanding how cell therapies navigate the three-dimensional tumor microenvironment and allow the measurement of cell-to-cell interactions.

Focused on developing and deploying the critical climate solutions our world needs to reach net-zero emissions by 2050.

Investment focus

Energy, Renewable Energy, Manufacturing
Series A, Series B, Funding Round
United States, Canada, United Kingdom

Portfolio highlights

Fervo Energy — Fervo Energy delivers 24/7 carbon-free energy through development of next-generation geothermal projects.
Deep Sky — Deep Sky is building infrastructure to scale CO2 removal. Deep Sky will remove millions of tons of CO2 from the atmosphere and permanently store it underground, back where it belongs. A new benchmark for Scope 3 Emissions: durable, scalable, and inherently measurable and verifiable.
Heirloom — Heirloom is restoring balance to our atmosphere by removing 1 billion tons of carbon dioxide by 2035. We use natural processes to engineer the world's most cost-effective Direct Air Capture solution.

Intel Capital invests in innovative startups targeting cloud and AI infrastructure, edge, 5G, autonomy, cybersecurity, client & gaming, enterprise applications, silicon design and manufacturing, and a wide range of other disruptive technologies.

Investment focus

Software, Information Technology, Enterprise Software
Series B, Series A, Series C
United States, China, Israel

Portfolio highlights

Tuskira — Tuskira integrates data from 150+ tools into an AI-driven security mesh, automating assessments, optimizing defenses, and mitigating risks in real-time.
Ayar Labs — Ayar Labs solves bandwidth and power bottlenecks by moving data using light. We built the world's first optical I/O chiplets.
Aira Technologies — Revolutionizing Wireless Networking using Machine Learning and AI

Flybridge is an early-stage venture capital fund with 20+ years of investing experience and over $1B under management. Flybridge has offices in New York and Boston.

Investment focus

Software, Artificial Intelligence, SaaS
Seed, Series A, Series B
United States, Brazil, Canada

Portfolio highlights

Agtonomy — Agtonomy is a hybrid autonomy and tele-assist platform for agriculture vehicles.
Noetica AI — Instant benchmarking for the terms of your next deal. Leveraging the industry's largest knowledge graph of corporate debt, securities, and M&A transaction terms.
ForceMetrics — ForceMetrics keeps communities safe by providing first responders and city leaders with the critical context they need.

Asymmetry Ventures invests in scalable early-stage companies with exceptional defensibility.

Investment focus

Software, Health Care, Biotechnology
Seed, Pre-Seed, Series A
United States, India, United Kingdom

Portfolio highlights

TransCrypts — We all have that file box where we throw all our important documents. Our goal at TransCrypts is to make that box digital and have all the documents secured through the blockchain. We currently offer industry leading privacy and security standards on our file storage and sharing platform and have solutions for individuals all the way to enterprises.
Reforged Labs — Reforged Labs | Effortless AI Ads for Mobile Game Studios.
SFA Therapeutics — SFA Therapeutics is a development-stage bio-pharmaceutical startup company focused on a new advancement in the treatment of chronic inflammatory disease - the use of microbiome-derived metabolites as drugs.

Palo Alto based Eclipse Ventures partners with entrepreneurs boldly transforming the essential industries that define and propel economies. Learn more.

Investment focus

Software, Robotics, Artificial Intelligence
Series A, Series B, Seed
United States, Canada, Israel

Portfolio highlights

Simbe Robotics — Better retail for all. Get shoppers what they want, your teams what they need, and brands what they've been craving.
Starboard — Starboard revolutionize global trade by empowering SMB freight forwarders with cutting-edge AI tools.
Capstan Medical — Capstan Medical is creating minimally invasive technologies to treat heart valve disorders.

Advantage Capital has invested over $3.8 billion in more than 800 portfolio companies and projects nationwide since 1992. The firm specializes in growth equity, lending, and mezzanine debt capital investments spanning three distinct but complementary themes, driving local economic development and lasting impact in underserved communities.____________________Growing Small Business // 800+ PORTFOLIO COMPANIES // 34 STATES // 66,000+ JOBS SUPPORTED // Small businesses and the entrepreneurs who power them are fundamental to the U.S. economy, driving inclusive economic expansion that allows people and communities to thrive. Advantage Capital offers debt and equity investment opportunities and can provide senior, unitranche and subordinated debt, as well as minority equity financing. The firm invests in companies from a diverse array of industry sectors, including manufacturing, technology and business services, among others. It seeks to make an initial investment between $500K and $10M in companies with $1M+ EBITDA.Financing Affordable Homes // 89 PROJECTS SINCE 2015 // 8,000+ FAMILIES & SENIORS HOUSED // 7 STATES // Creating stronger communities goes beyond business investment and jobs. Financing housing in these same communities creates even more positive and lasting impacts.Expanding Renewable Energy Solutions // $130M IN CAPITAL DEPLOYED // 65 PROJECTS // 20,000+ HOMES POWERED // Increased access to renewable energy supports local green jobs and economic development while building the framework for tomorrow's carbon-free America. ____________________Geographic Focus: Advantage Capital is committed to impact nationwide, with current emphasis in the following states: Alabama, Arkansas, Connecticut, Florida, Georgia, Illinois, Kansas, Kentucky, Louisiana, Michigan, Mississippi, Missouri, Nebraska, Nevada, New Mexico, Ohio, Pennsylvania, Tennessee, Texas, Utah, Virginia, West Virginia____________________Advantage Capital is headquartered in New Orleans, Louisiana and has offices in the following locations: St. Louis, MO; New York, NY; Austin, TX; Hanover, NH; Washington, D.C.; Napa, CA; Nevada.

Investment focus

Manufacturing, Software, Health Care
Debt Financing, Funding Round, Series A
United States, China, Canada

Portfolio highlights

Cloverleaf.me — Cloverleaf helps build great work teams and improve employee engagement using assessments like Enneagram, DISC and 16-Types to identify team strengths and coach work teams to work better together.
Whitman Controls — Whitman Controls specializes in the manufacture of miniature pressure, vacuum, temperature, and liquid level switches and sensors.
Malones CNC Machining Inc. — Malone's CNC Machining Inc. is a manufacturer of military aircraft parts and assemblies.

Prelude Ventures invests in and supports early-stage startups with the greatest potential to mitigate climate change. For us, climate is everything.

Investment focus

Software, Energy, Manufacturing
Series A, Series B, Series C
United States, Canada

Portfolio highlights

LuxWall — LuxWall is accelerating the global transition to net zero by upgrading windows and glass into transparent insulation for buildings.
RedoxBlox — RedoxBlox offers thermochemical energy storage technology for natural gas power plant operators. It helps power plant operators drastically reduce carbon and nitrogen oxides emissions, its solution integrates with the existing natural gas power plant infrastructure, minimizes impact on plant total capital costs, increases grid resiliency andsafety, and is recyclable, non-toxic, and non-combustible, enabling industries with renewables grid through the deployment of large-scale long-duration energy storage.The company was founded in 2020 and is based in East Lansing, Michigan.
Form Energy — Form Energy is developing, manufacturing, and commercializing a new class of cost-effective, multi-day energy storage systems.

Maine Angels they make investments with entrepreneurs with an emphasis on businesses.

Investment focus

Software, Health Care, Biotechnology
Seed, Funding Round, Series A
United States

Portfolio highlights

HighByte — Architect your digital transformation with proven Industrial DataOps software from HighByte. Let's make your industrial data useful.
TOP the organic project — 100% Organic Cotton Period Care. Organic Tampons, Pads, First Period Kit & Bulk Period Products. Women-owned, eco-friendly, plant-based and sustainable. With every subscription, TOP gives back to women in need.
Pumpspotting — connect over breastfeeding, milk, motherhood, and the best places to nurse and pump. nurse, pump, nourish, connect.

Creative Ventures is a deep tech venture firm investing in early-stage companies solving humanity’s most critical crises. Led by a team of world-class experts, our deep tech acumen is informed by rigorous research, unmatched market understanding, and the dedication to lead our companies to success.Today’s problems can’t be solved by yesterday’ssolutions. Let’s get Creative.

Investment focus

Software, Health Care, Biotechnology
Seed, Series A, Funding Round
United States, Canada, United Kingdom

Portfolio highlights

Relectrify — Unlocking extra lifetime and performance of batteries via advanced battery management (BMS) technology.
Tierra Biosciences — Speed, scale and simplicity with protein synthesis on-demand. Discover your portal to thousands of custom proteins. Get testable material with a single input.
Picnic — The Picnic Pizza System is a modular, easy-to-use, automated pizza assembly system that saves time, money, and labor without compromising quality.

Systematic Pre-Seed Startup Capital

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Convertible Note
United States, Canada, United Kingdom

Portfolio highlights

Averi — Averi is an AI-powered marketing management platform that combines proprietary AI models for marketing strategy and content creation.Design modern strategy, analyze massive amounts of data, create endless content from ads and social posts to blogs and whitepapers, build perfect-fit teams of marketing experts, and manage your entire growthoperation in one seamless experience.
UBILD — A.I powered construction workforce and vendor procurement platform
Hutsy — Hutsy helps you budget, spend less and offers a concierge service to handle tasks like negotiating bills, canceling subscriptions, saving you time and money.

Congruent Ventures is a venture capital firm that seeks to invest in Mobility and Urbanization, Energy Transition, Food and Agriculture, and Sustainable Production & Consumption sectors. We look for technology companies that will positively impact our energy and resource consumption. If we see an opportunity to partner with a like-minded teamfocused on scale across hardware, software, or services, we’re interested.

Investment focus

Software, Energy, Renewable Energy
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

AMP — AMP Robotics creates a scalable robotic system that reduces the cost of recycling and enables smart recycling facilities. AMP Robotics' solution is a combination of computer vision and machine learning with robots that can identify and rapidly pick recyclable materials off a conveyor belt for market and recovery.AMP Robotics automates theidentification, sorting, and processing of material streams to extract value for material recovery facilities (MRFs) that process municipal solid waste, construction and demolition, e-waste, and auto-shredding. The company's engineering design reduces the cost of capital investment with modular implementation easily dropping into existing facility infrastructure without costly retrofits or interruption to operations.AMP Robotics was founded on 2015 and is headquartered in Louisville, Colorado.
Fervo Energy — Fervo Energy delivers 24/7 carbon-free energy through development of next-generation geothermal projects.
Energetic Capital — Let us cover the payment default risk on your next Solar Project. Energetic Insurance makes efficient financing possible for financiers, investors and energy service providers with the EneRate Credit Cover solar insurance policy.

MB Venture Partners in Memphis, TN provides venture capital for life sciences: medical device, biotechnology companies, products for musculoskeletal diseases

Investment focus

Health Care, Medical, Medical Device
Seed, Series B, Series C
United States, Israel

Portfolio highlights

Cast21 — The future of orthopedic technology has arrived. Cast21 braces are designed for your active lifestyle.
SweetBio — SweetBio is a Memphis, Tennessee based medical device company specializing in bioengineering honey-incorporated materials for wound care.
Lineus Medical — Lineus Medical is a medical device company focused on reducing IV complications for patients and providers all over the world.

Kleiner Perkins is a venture capital firm specializing in investing in early-stage, growth, and incubation companies. The firm continues that legacy, investing in founders with bold ideas that span industries and continents, partnering with them from inception to IPO and beyond to maximize the potential of their ideas. They also focus on earlycomputer firms using their devices and programming and service companies. It also invests in the digital, life sciences, and healthcare industries.

Investment focus

Software, Health Care, Information Technology
Series B, Series A, Series C
United States, China, United Kingdom

Portfolio highlights

Terradot — The Earth Regeneration Company
Enterpret — All customer feedback categorized automatically, combined with advanced analytics capabilities that ensure no customer pain goes unnoticed.
Hippocratic AI — The First Safety Focused LLM for Healthcare

Root Ventures is a seed-stage venture capital firm that invests in technical teams working on deep tech. The firm specializes in the fields of financial services, venture capital, and investments. It was founded in 2013 and headquartered in San Francisco, California.

Investment focus

Software, Artificial Intelligence, Machine Learning
Seed, Series A, Series B
United States, Canada, Denmark

Portfolio highlights

Trieve — Trieve provides search teams with infrastructure for retrieval and RAG.
Integrated Biosciences — Integrated Biosciences is the first company in history to be able to virtually stress cells.
CruxOCM — Crux OCM: Automate your oil and gas control room operations

A home for Tough Tech founders.

Investment focus

Biotechnology, Health Care, Manufacturing
Seed, Series A, Series B
United States

Portfolio highlights

Osmoses — Osmoses is a cleantech company that is transforming chemical separations. Its mission is to eliminate energy waste with efficient membrane technology, reducing production costs for customers and CO2 emissions for the environment. Hydrogen, carbon capture, and renewable natural gas are some of the in
Amide Technologies — Amide synthesizes peptides that are difficult to obtain through existing means, bridging the gap between traditional solid phase peptide synthesis and biological expression. By using unnatural amino acids and artificial protein backbones, our team is expanding what is biologically possible. Amide’s Automated Fast Flow Peptide Synthesizer (AFPS)leverages flow to dramatically improve solid phase peptide synthesis. Using the power of flow, we can generate highly reactive intermediates in situ, maintain excellent heat and mass transfer, and achieve much better synthetic outcomes than alternative SPPS methods. With all these advantages, AFPS allows biopharma pioneers to dramatically re-think what’s possible. Let Amide broaden your horizons with better, faster synthesis.
Vaxess Technologies — Vaxess engineers novel technologies that uniquely engage the human immune system, enabling improved efficacy and simplified access for vaccines and therapeutics.

Climate Capital is an investment firm that supports companies that directly or indirectly reduce global greenhouse gas emissions.

Investment focus

Energy, Manufacturing, Biotechnology
Seed, Pre-Seed, Series A
United States, Germany, Canada

Portfolio highlights

Circe — Circe grows their food through fermentation. Using the right fats they make food people want to eat and use CO2 as a feedstock to scale production in an economically viable and climate-friendly way.
Zitara — Zitara builds software that empowers companies to deeply understand their batteries, both in design and deployment. We support the renewable energy revolution, powered by safer batteries, at a lower cost, with less waste.
Rosy Soil — Crafted for the specific needs of indoor plants, this blend contains all-natural, renewable ingredients that optimize drainage, deliver plant-boosting nutrients, and support a diverse community of beneficial fungi and microbes.

We help the daring build legendary companies.

Investment focus

Software, Information Technology, Enterprise Software
Series B, Series A, Series C
United States, China, India

Portfolio highlights

Safara — Book over 1M hotels that are carbon offset for free on Safara, plus get insider travel recommendations and enjoy an unbeatable loyalty program.
Decart — Decart is an AI platform significantly improves the training and inference of large generative models.
Stainless — With Stainless, you can deliver idiomatic SDKs while you stay focused on building the API.

Early-stage venture capital fund focused on investments in technology companies within the supply chain, manufacturing and digital industrial sectors

Investment focus

Software, Logistics, Supply Chain Management
Seed, Series A, Pre-Seed
United States

Portfolio highlights

Pandion — Pandion has developed a technology platform for e-commerce players to manage capacity problems during peak periods. The logistics platform helps all businesses provide one and two-day shipping, and makes on-time delivery possible for more retailers, regardless of size and scale. Pandion’s delivery management software uses machine learning to avoidshipping delays and optimize delivery networks.
Wilya — Reimagine the future of Industrial Work. ; Unlock Talent Pools. Millions of people are not able to work 8 hours a day or 5 days a week. ; Increase Diversity. Gig and Take helps you create and mange a flexible workforce.
Reshape Automation — AI-powered industrial automation marketplace and platform that simplifies the discovery, design, deployment, and support of automation

Threshold is an early-stage venture capital firm that focuses on a high-conviction investment strategy. The firm partners with entrepreneurs to build innovative consumer, enterprise, and healthcare technology companies.

Investment focus

Software, Internet, Mobile
Series B, Series A, Series C
United States, India, Canada

Portfolio highlights

Mendaera — Mendaera enables all healthcare providers to perform precise and consistent point-of-care interventions. Their platform combines real-time imaging, robotics, and artificial intelligence to aid physicians in image acquisition and interpretation.
Numa — Turns BDCs and Advisors into world-class communicators, using visibility + accountability + a healthy dose of AI superpowers
Numa — Leverage modern Generative-AI to autonomously capture every RO, schedule service appointments, and deliver service updates in real time.

Draper Associates, founded in 1985, is a seed-stage venture capital firm that helps entrepreneurs to drive their businesses to greatness. We understand that a great company takes time to build and we'd like to ensure that entrepreneurs are in for the long haul.

Investment focus

Software, FinTech, Information Technology
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Rise — We make it easy for you to find, hire, pay, and manage contractors internationally while ensuring full compliance. Pay your team in fiat or crypto.
Rosy Soil — Crafted for the specific needs of indoor plants, this blend contains all-natural, renewable ingredients that optimize drainage, deliver plant-boosting nutrients, and support a diverse community of beneficial fungi and microbes.
Firehawk Aerospace — Firehawk Aerospace builds hybrid rocket engines that throttle by 3D printing rocket fuel improving safety, reliability, and cost-efficiency.

Investing in the Near Frontier

Investment focus

Biotechnology, Software, Health Care
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

Salient Motion — A next-generation supplier for aerospace and defense, specializing in advanced electric propulsion.
The Lumber Manufactory — Enabling timberland owners to get the most out of their land.
Intramotev — Intramotev Autonomous Rail manufactures autonomous zero-emissions rail vehicles to advance the future of freight movement. Intramotev's vehicles provide efficient and cost-effective movement of materials across specialized private railroads for mines, manufacturing facilities, ports, and more that is autonomous and fully battery-electric,enabling rail and mining industries to get lower emissions than diesel-electric locomotives and diesel trucks, shorter stopping distance, and steeper grade capability than existing trains.

We are deep tech venture capital.

Investment focus

Software, Artificial Intelligence, Health Care
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

Radiant — Clean. Portable. Safe. Energy
Fervo Energy — Fervo Energy delivers 24/7 carbon-free energy through development of next-generation geothermal projects.
Slip Robotics — Auto-load and auto-unload any truck in 5 minutes with SlipBots to drive 10X speed, safety, and savings across the supply chain. With Slip, truckers don't wait and forklift drivers don't risk it.

Liquid2 Ventures provides technology startups with seed-stage investments and is based in San Francisco, California. The firm was founded in 2015 by Joe Montana, Mike Miller, and Michael Ma.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Series A, Pre-Seed
United States, Mexico, Canada

Portfolio highlights

FINNY — Double down on your niche. Cut out the noise. Grow organically, effortlessly
Twenty — Experience the forefront of open-source CRM. Packed with advanced features, customizable workflows, and community support. Transform customer relationship management seamlessly and efficiently.
Pixeltable — Open Source Python framework that enables AI Engineers to focus on modeling and experimentation.

Ben Franklin helps early-stage technology companies and established manufacturers translate innovation into commercial success and economic prosperity.

Investment focus

Manufacturing, Health Care, Software
Grant, Seed, Debt Financing
United States, United Kingdom, Brazil

Portfolio highlights

Venseca — Venseca is a global leader in digital trust. Our patent-pending solution generates Digital Trust Scores and comprehensive, independently validated reports to help you understand the cyber risk profile of all of your suppliers.
UnityLab — Welcome to UnityLab, home of the best small business & brand builders dedicated to business technology, operations, finance, & sales tools.
Tolerance Bio — Tolerance Bio will increase health span by preserving and restoring the function of the thymus, the master regulator of immune tolerance. Immune-mediated diseases represent a significant unmet medical challenge: cancer, autoimmunity, transplant rejection, infections, immune deficiencies, and allergi

Good Growth Capital is an early-stage venture capital firm known for its expertise in finding, assessing and cultivating complex science and technology.

Investment focus

Health Care, Information Technology, Biotechnology
Seed, Series A, Convertible Note
United States, France, Israel

Portfolio highlights

Liminal — Advanced battery inspection and metrology with ultrasound and machine learning
Aralez Bio — Aromatic noncanonical amino acids that are made using biocatalysis. Single step, enzyme synthesis makes hundreds of tryptophan and other amino acid analogs!
AdipoPharma — By harnessing the power of the Adipocyte AdipoPharma is committed to developing innovative treatment for type 2 diabetes

BoxGroup is an early stage investment fund focused on technology companies. Contact Us: hello@boxgroup.com

Investment focus

Software, Health Care, Internet
Seed, Series A, Series B
United States, France, Mexico

Portfolio highlights

Gigs — Gigs is building Stripe for SIM cards. Providing platforms custom phone & data plans through an easy to use API in 180+ countries.
Prima — Reliable manufacturing & supply chain partner for custom parts, metal fabrication & efficient sourcing from Mexico. Manage design, production & delivery
Tempest — Tempest is a ready-to-use self-serve platform that enables developers to automate app development, deployment, and management while ensuring security and compliance.

Collaborative Fund is a leading source of capital for entrepreneurs pushing the world forward.

Investment focus

Food and Beverage, Software, Health Care
Seed, Series A, Funding Round
United States, United Kingdom, South Korea

Portfolio highlights

WeaveGrid — WeaveGrid operates with utilities and owners of electric vehicles (EV) to allow and speed up transportation electrification. Using machine learning, optimization, and predictive analytics, the company's software solution solves several EV-grid integration challenges for utilities in a systems-oriented manner; helps integrate renewable energyresources on the grid; and saves utility customers' money on their bills.
one.bio — BCD Bioscience is an emerging biotechnology spinout from UC Davis that creates ingredients for food and biopharmaceutical applications. The company was founded in 2019 and is headquartered in Davis, California, United States.
Brightly Ventures — High-integrity carbon credits that fund food recovery in your community.

A home for Tough Tech founders.

Investment focus

Biotechnology, Health Care, Manufacturing
Seed, Series A, Series B
United States

Portfolio highlights

Osmoses — Osmoses is a cleantech company that is transforming chemical separations. Its mission is to eliminate energy waste with efficient membrane technology, reducing production costs for customers and CO2 emissions for the environment. Hydrogen, carbon capture, and renewable natural gas are some of the in
Amide Technologies — Amide synthesizes peptides that are difficult to obtain through existing means, bridging the gap between traditional solid phase peptide synthesis and biological expression. By using unnatural amino acids and artificial protein backbones, our team is expanding what is biologically possible. Amide’s Automated Fast Flow Peptide Synthesizer (AFPS)leverages flow to dramatically improve solid phase peptide synthesis. Using the power of flow, we can generate highly reactive intermediates in situ, maintain excellent heat and mass transfer, and achieve much better synthetic outcomes than alternative SPPS methods. With all these advantages, AFPS allows biopharma pioneers to dramatically re-think what’s possible. Let Amide broaden your horizons with better, faster synthesis.
Vaxess Technologies — Vaxess engineers novel technologies that uniquely engage the human immune system, enabling improved efficacy and simplified access for vaccines and therapeutics.

Investing catalytic capital in promising seed stage companies located outside of Silicon Valley, NYC & Boston. Backed by a group of iconic entrepreneurs, executives & investors.

Investment focus

Software, SaaS, Information Technology
Seed, Series A, Funding Round
United States, Canada, Argentina

Portfolio highlights

Knit — Knit helps researchers run agency-quality quant + qual research at DIY costs, by taking the most time-intensive research tasks off their plate through Researcher-Driven AI.
Sigo Seguros — Sigo uses data and automation to provide lower-cost policies for the Latino market.
Gig Wage — Instant payouts for 1099 contractors and easy contractor payroll. 1099 Payments & Payroll APIs. Stay compliant with Gig Wage. Sign up free.

Largest and most active angel group in the Pacific Northwest

Investment focus

Software, Health Care, Mobile
Seed, Funding Round, Series A
United States, Canada, Nigeria

Portfolio highlights

Glidance — Glide, a groundbreaking leap in assistive technology, is the first self-guided mobility assistant designed for individuals with sight loss.
Give InKind — Set up a Give InKind Page to coordinate support from anywhere. Create a Care Calendar, add items to your Wishlist and connect your Crowdfunding - all for free.
SafKan Health — OtoSet® by SafKan Health is the first FDA Cleared automated ear cleaning device for the 35 million Americans affected by impacted earwax - the leading cause of conductive hearing loss.

Lerer Hippeau is an early-stage venture capital fund based in New York City. As founders and operators ourselves, we see returns in relationships

Investment focus

Software, E-Commerce, Internet
Seed, Series A, Series B
United States, Canada, United Kingdom

Portfolio highlights

MOTORMIA — Meet Mia! MOTORMIA - Curated by auto enthusiasts, powered by AI. MOTORMIA is revolutionizing personalized discovery of aftermarket upgrades for your enthusiast vehicle
Conflixis — Conflixis develops conflict monitoring platform intended to manage conflicts inside organizations.
Symbiotic Security — Symbiotic Security revolutionizes cybersecurity with an AI-driven coach, offering real-time detection, remediation, and training within the developer's IDE.

Bolt: Investing at the intersection of the digital and physical worlds

Investment focus

Software, Health Care, Hardware
Seed, Pre-Seed, Series A
United States, Canada

Portfolio highlights

FYTO — Revolutionary Sustainable Agriculture
Blackbird — We believe the next great hospitality technology platform should connect restaurants and their customers directly, in meaningful and ongoing ways. Blackbird is founded by a team with a passion for restaurants and a track record of using technology to solve problems.
Foundation — Self custody is finally attainable. Secure your Bitcoin with an unprecedented combination of elegance and ease of use.

CEVG is an angel investor collective that invest in and mentors early-stage cleantech and climatetech startups across North America.

Investment focus

Energy, Renewable Energy, Manufacturing
Series A, Seed, Funding Round
United States, Canada

Portfolio highlights

PeakSyncer — PeakSyncer, a product of Zhong Xi Group, LLC, is an AI-powered cloud platform that offers a comprehensive solution for utilities aiming to optimize their energy management systems through advanced technology. The platform focuses on demand response programs, utilizing artificial intelligence to automate and streamline the management of peak energyloads. PeakSyncer has focused on creating cutting-edge solutions in cloud computing and AI integration. The company positions itself as a leader in the energy management sector, working on delivering reliable, user-friendly solutions that adapt to the evolving needs of energy grids. With dedicated support and 24/7 monitoring, PeakSyncer aims to empower utilities to modernize their operations and optimize resource usage effectively.With PeakSyncer, the company addresses a critical business need for seamless data synchronization across platforms such as ERP, CRM, and other essential business software. The platform’s key advantage is its ability to adapt to dynamic data patterns, learning from past syncs to continuously improve syncing accuracy and efficiency.PeakSyncer is designed to be scalable and easily integrates with existing utility infrastructure, ensuring a smooth implementation process. The platform not only helps utilities meet regulatory requirements but also supports them in creating a sustainable energy ecosystem by engaging customers in demand response initiatives, made possible by AI algorithms that analyze and anticipate potential data issues before they disrupt business processes.
Cala Systems — Discover Cala, the innovative heat pump water heater that customizes heating to your lifestyle. Save money, reduce your carbon footprint, and enjoy easy installation with Cala. Reserve yours today and experience efficient, eco-friendly hot water tailored to your needs.
Electrified Thermal Solutions — Electrified Thermal Solutions, Inc. is developing the Joule Hive: a new energy storage technology that converts surplus zero-carbon electricity into heat.

Wisconsin Investment Partners is an Angel Investment Group in Madison, Wisconsin founded in 2000 with 20 members. Membership has grown to 50+ members in recent years, bringing significant knowledge and experience.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Seed, Series A
United States, Canada, United Kingdom

Portfolio highlights

Flyte — Flyte promotes cellular healing in pelvic floor muscles for lasting results. Flyte is fast, proven, safe, pelvic floor therapy for bladder control.
BeeReaders — ## Build Setup
Midwest Games — Midwest Games is a video game publisher focused on creating opportunities for the abundant talent across the Midwest and other underrepresented regions.

Safar Partners is a seed- to growth-stage venture fund investing primarily in technology companies out of MIT, Harvard, and the University of Rochester. We invest in platform technologies in the cleantech and advanced materials, AI/IT and robotics, and life science/medical device areas.

Investment focus

Biotechnology, Health Care, Manufacturing
Seed, Series A, Series B
United States, China

Portfolio highlights

Active Surfaces — Active Surfaces is commercializing MIT-developed ultra-thin-film solar technology.
Lucy Therapeutics — Lucy Therapeutics, a Boston-based biotech with a unifying mitochondrial platform, is developing small molecule treatments for neurological diseases.
Ancilia Biosciences — A CRISPR route to success for live biotherapeutics & bacterial products

Gaingels is a leading venture investment syndicate in support of diversity, inclusive of the LGBTQIA+ community and allies in the venture capital space.

Investment focus

Software, Health Care, Artificial Intelligence
Seed, Series A, Series B
United States, Canada, Mexico

Portfolio highlights

MealMe — MealMe: We compare services for delivery pickup and groceries to ensure that we are the fastest food delivery app, the cheapest food delivery app, and the food delivery app with the largest selection.
OneRail — OneRail is a final mile delivery orchestration platform providing real-time visibility, actionable data, and data-driven optimization capabilities for its enterprise clients. OneRail’s cloud-based “delivery switch” simplifies same-day and on-demand delivery execution by connecting the demand signal (POS, eCommerce, ERP) with the ecosystem ofdelivery networks and internal fleets in real-time. The result of OneRail’s centralized view of disparate final mile data enables data-driven optimization, positively impacting the dependability, speed, and cost of final mile fulfillment.
Further — Further is on a mission to empower first-time home buyers to achieve their dream of homeownership with confidence and ease. We simplify the complex home buying process through innovative tools and personalized guidance, ensuring that buyers are well-prepared every step of the way. Our platform offers financial planning, tailored insights, andresources designed to make homeownership more accessible. At Further, we believe that with the right support, anyone can realize their goal of owning a home. Join us as we help make the path to homeownership clear and attainable for all.

Applied Ventures, LLC, is the venture capital arm of Applied Materials, Inc., (NASDAQ: AMAT) investing in innovative startups for over a decade.

Investment focus

Manufacturing, Semiconductor, Electronics
Series B, Series A, Funding Round
United States, South Korea, France

Portfolio highlights

Ionblox — High energy density lithium ion batteries for ground and aerial electric vehicles
Scintil Photonics — SCINTIL Photonics develops and markets Heterogeneous Silicon Photonic IC with wafer-level lasers integration.
Infinitum Electric — Infinitum Electric is a motor technology company delivering lightweight and IoT-enabled electric motors. It is at the forefront of making electric motors more efficient, more durable, lighter weight, and less expensive. Their disruptive motor and control products utilize their patent-pending Printed Circuit Board (PCB) stator technology and providebroad application across multiple industries. They work with global manufacturers and industrial OEMs to customize their technology for specific applications and market segments.

Launch NY is a nonprofit venture development organization in Upstate New York. We provide pro bono mentoring and access to risk capital for high-growth startups.Are you ready to launch?Check out our NEW Resource Navigator under the "Entrepreneurs" tab for the most up-to-date opportunities for entrepreneurs! Apply Now Invest Now Donate Now Entrepreneurs Launch Your

Investment focus

Health Care, Software, Food and Beverage
Convertible Note, Seed, Pre-Seed
United States, Canada

Portfolio highlights

Nudge Money — Nudge Money is an AI financial guidance platform leveraging behavioral economics and financial planning to infuse timely and personalized advice into automated marketing channels at community financial institutions and fintechs, increasing conversion 7x while building loyalty.
Caretech Human — Automated solution for continuous health monitoring and diseases prevention
Refraction — Refraction provides DealerTrack-powered Auto Dealers a white-label eCommerce marketplace that seamlessly integrates with your existing web site. It only takes 5 minutes to get you from setup to selling. Why Refraction? There has never been a more critical time to FUTURE-PROOF your business as car buyers look to the internet to buy their next car.

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