Top 50 SaaS Startup Investors in Puerto Rico (October 2026)

Portfolio highlights

• Toteat — Headquarters located at Vitacura 2771, of. 504, Las Condes, Santiago de Chile
• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• BackChannel — BackChannel is an online B2B platform for inventory transactions and for buying and selling online goods.

Portfolio highlights

• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.
• Ole Insurance Group — Ole Insurance Group focuses on offering protection and well-being products and services through technology. Ole Insurance Group was founded in 2021 and was headquartered in Puerto Rico.

Portfolio highlights

• Wirelane — Driven by the mission "We empower people to move towards a clean future", Wirelane has been designing sustainable mobility since 2016 and is developing innovative complete solutions for the construction, operation, and marketing of charging infrastructure. Wirelane provides its customers with all the necessary service modules, rangingfrom cutting-edge charging technology to a digital management and billing platform, as well as comprehensive installation and operation services.
• Flashcookie — Flashcookie is an on-demand merchandise for independent artists based in Buenos Aires, Argentina.
• Solve Therapeutics — Solve Therapeutics is a biopharmaceutical company that develops Antibody Drug Conjugate and Bispecific Therapeutics. The company was founded in 2021 and is headquartered in Belmont, California.

Portfolio highlights

• Luminoah — Discover Luminoah Flow, the world's smallest enteral nutrition delivery system designed for your active lifestyle. Empower your nutrition journey today.
• Cloverleaf AI — Cloverleaf AI turns 1.5 million government meetings into early buying signals, so you reach buyers before the RFP. Government sales intelligence for B2G sellers.
• Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Portfolio highlights

• Chomp — Chomp is a social network platform that focuses on on question-and-answer with prediction-based systems.
• Techdollar — Techdollar operates a private credit platform that originates and underwrites loans secured against private company equity. The service enables late-stage startup founders, employees, and institutional investors to unlock liquidity from their shares without triggering a taxable sale or losing long-term upside.
• ARO Network — ARO Network is a decentralized edge cloud platform focusing on power peer-to-peer content delivery.

Portfolio highlights

• IMUA — Follow us @imua
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Valinor — Institutional capital solutions at the intersection of credit and blockchain

Portfolio highlights

• Neosoul — NeoSoul uses an open architecture with autonomous agents operating under user-defined constraints to link agent intelligence, deterministic capital controls, and verifiable market execution.
• ORO — ORO is an AI-powered DeFi companion that lets users manage, trade, stake, lend, and research crypto assets through natural-language conversations, ORO aims to simplify onchain finance by bringing portfolio management and DeFi actions into one conversational interface.
• GAEA — GAEA is a decentralized artificial intelligence training network and data infrastructure platform focused on building a comprehensive multimodal emotional database.

Portfolio highlights

• Quibble — Price Optimization and Revenue Management Software and Consulting For Vacation Rentals & Alternative Accommodations - We created Quibble to address the gap in the market between the simple rules-based software applications currently available and a truly science-based optimization. Quibble bundles our software with a full service offering togive our clients complete Pricing Ease of Mind. With many years of revenue management experience in the travel and hospitality industries, we know the pains and uncertainty revenue management brings. At Quibble, we aim to increase your revenue performance by engineering and implementing your custom pricing strategy while developing long-lasting partnerships.

Portfolio highlights

• Knit — Knit is an AI-Native Research Agency that combines the rigor and expertise of a traditional agency with the speed and efficiency of AI.
• Buildforce — Amping up America's electrical workforce
• Just Women's Sports — Just Women’s Sports Inc. is a digital-first consumer media brand 100% dedicated to covering women’s sports. Through daily content including podcasts, newsletters, online content and social media, Just Women’s Sports brings you everything you need to see and know in the world of women’s sports.

Portfolio highlights

• Techdollar — Techdollar operates a private credit platform that originates and underwrites loans secured against private company equity. The service enables late-stage startup founders, employees, and institutional investors to unlock liquidity from their shares without triggering a taxable sale or losing long-term upside.
• Optimum — The Universal Data Acceleration Network | Powered by RLNC
• Doppler Finance — Rebuilding Capital Markets for the Tokenized Era.

Portfolio highlights

• IMUA — Follow us @imua
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — The full stack AI GTM solution. We help your brand grow on autopilot.

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• PERPTools — PERPTools combines crypto perpetual trading with activity points and risk-free market predictions.
• Open Campus — The Open Campus is a community-driven protocol that leverages the power of blockchain and invites all to build the future of education by putting the power of learning back in the hands of educators, students, and the community.

Portfolio highlights

• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• Inaam — inaam is an Australian impact investing app. Pick five themes, customise them yourself, and read every company you hold by name. A flat $10 a month subscription, and a $100 minimum to start in the fund.
• PayToMe.co — PayToMe.co offers innovative and secure payment solutions including text-to-pay, digital invoicing, and digital checkbook services.
• Kybele's Garden — Kybele's Garden focus on algae-based bioponics and algae fermentation methods. Their differentiation strategy boosts harvest yield, source efficiency, and functional content, while improving sensory attributes and shelf life. These technologies can be used in agrifood and skin care, and integrated into existing producers' systems.

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• CARV — CARV enables AI Beings to live, evolve, and govern as sovereign intelligences on-chain; not as tools, but as beings that act, learn, and lead.
• Nest Wallet — A Wallet Built for Traders

Portfolio highlights

• AEON — Powering #agenticeconomy #x402 | AEON is settlement layer bridging autonomous AI interactions (A2A & A2M) with real-world value flows. Backed by @yzilabs $AEON
• Slinky Network — Slinky Network provides an on-chain marketplace and payment protocol that connects AI agents and applications with third-party APIs. The company offers the SlinkyLayer platform, which wraps developer endpoints as discoverable skills and exposes them through an x402 pay-per-execution interface. Each API call triggers a non-custodial on-chainmicropayment, settling in the same request loop using networks such as Base and BNB Chain. Developers set prices, earn a defined revenue share, and receive instant payouts to their wallets without subscriptions or custodial holds. AI agents authenticate via wallet signatures, enabling autonomous, machine-to-machine access and payment without traditional logins or credit cards. The platform also records call ratings on-chain to provide portable, verifiable reputation for services.
• Shanghai Molian Technology — Shanghai Molian Technology is an intelligent agent communication infrastructure platform

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.
• NexGen Cloud — Discover NexGen Cloud's innovative AI cloud solutions designed for seamless scalability, high performance and robust security. Lead AI innovation with NexGen Cloud.

Portfolio highlights

• Novastro — Building the PayFi layer for stablecoin-powered payments, settlement, and real onchain financial utility.
• Shiba Inu Coin — Shiba Inu Coin is an Internet Publishing Company.
• Router Protocol — Router Protocol is a Cross Chain Bridge. Currently live on Ethereum, Polygon, and more. Building an interoperable cross chain future of the blockchain ecosystem.

Portfolio highlights

• Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
• Mauve — Fully Compliant, Non-Custodial Exchange
• Center — Start point for your next NFT app.

Portfolio highlights

• DataRoot — DataRoot provides data science and AI solutions, helping businesses leverage data for growth and optimization.
• Conectamos — Ship with local carriers, more affordable and reliable
• Frente — Nossa missão é transformar a forma com a qual as pessoas fazem câmbio. Unimos a experiência de profissionais com carreira consolidada no mercado financeiro a uma visão inovadora e contemporânea de negócios. Tudo com a potência que a tecnologia de dados trouxe para o universo Fintech.Somos a sua parceira de câmbio mais sólida e confiável, capaz deatender às suas demandas, superando desafios cada vez maiores e mais rápidos, em um mundo em constante transformação. Nossa preocupação verdadeira com um atendimento próximo, consultivo e atencioso, além de taxas acessíveis e preços justos, complementam a experiência que oferecemos. Tudo de forma a trabalharmos para diminuir a carga burocrática e processos engessados das grandes instituições financeiras.

Portfolio highlights

• TACEO — The privacy layer for public blockchains. Encrypted payments for institutions and agents. Backed by a16z CSX & Archetype.
• Due — Discover our global payment platform. Powered by open, decentralised and interoperable networks.
• Freename — Register Web3 domains, custom TLDs, or import domains. Secure your digital identity today.

Portfolio highlights

• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• Exocore — Exocore is the layer one blockchain for aggregated security.
• Exabits AI — Exabits' network of GPUs ranges from consumer-grade to H100s, offering the most cost-effective compute because we are obsessed with innovating performance.

Portfolio highlights

• Exocore — Exocore is the layer one blockchain for aggregated security.
• AstroForge — We mine asteroids to extract valuable minerals in space at a lower cost and smaller carbon footprint than the current terrestrial mining methods.
• Digital Harmonic — Digital Harmonic delivers AI-Driven software solutions with media, image and signal processing innovations. We empower commercial, government, and healthcare sectors with cutting-edge AI technology, delivering advanced software solutions to elevate clarity, precision, and mission-critical outcomes.

Portfolio highlights

• Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients
• San Jorge Children & Women's Hospital — San Jorge Children & Women's Hospital provides health care to children and women and enables excellent services to all patients.

Portfolio highlights

• CASIMIR —
• illumicell AI — illumicell AI combines patented AI algorithms and proprietary microscopy technology to test 50x faster, 20x more effectively, empowering every healthcare provider at the point of care – not just fertility clinics – with accessible, scalable fertility diagnostics.
• SignalRank — SignalRank Corporation is a FinTech company in the Venture space. It focuses on the seed stage asset class and uses data analytics to allocate capital to the best seed fund managers for their top performing companies. GPRank and CompanyRank are two proprietary algorithms it leverages to automate capital allocation. The company invests from balancesheet. Its customers are seed stage investors with outstanding companies in their portfolio.

Portfolio highlights

• Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
• Flowcarbon — Flowcarbon's versatile team merges investment banking, project finance, tax credit and other financial markets expertise to streamline access to creative capital solutions for the world’s most innovative companies in the infrastructure, decarbonization, and other niche sectors. Flowcarbon is headquartered in New York, United States and wasfounded in 2021.
• IntentX — The Future of Decentralized Derivatives

Portfolio highlights

• Coworked — Making enterprise change as seamless as day-to-day operations with Harmony, the headless-Al project manager. #ProjectManagement #AIProjectManagement
• furl — Remediating vulnerabilities at scale.
• Subject — Empower students with engaging, video-first curriculum from Subject.com for better outcomes in K-12 education. Increase graduation rates and student success.

Portfolio highlights

• Swarm Aero — Swarm empowers small teams to mobilize thousands of uncrewed vehicles in communications-limited, contested environments.
• Artemis — Artemis is the first protective layer that is AI-native
• littleBits Electronics — LittleBits is an open source library of over 60 electronic modules that snap together with magnets allows users to view, download, and share designs and make their own Bits through the use of prototypes. Deluxe kit, Smart home kit, Arduino coding kit, Synth kit, hardware development kit, and workshop set are some of the electronics learning modulesprovided by littleBits.LittleBits was launched by Ayah Bdeir in 2011 and is operated from New York, United States.

Portfolio highlights

• OP_NET — OPNET is a Bitcoin Layer 1 metaprotocol that enables smart contracts to function directly on the Bitcoin blockchain, without the use of sidechains or Layer 2 solutions.
• Modveon — The verified operating system for the modern nation state. Digital identity. Trusted communities. Sovereign financial rails. AI-native services.
• BridgePort — Crypto institutional middleware for off-exchange settlement. BridgePort's coordination layer connects exchanges and custodians for trading firm interoperability

Portfolio highlights

• Axal — Earn competitive returns on your crypto with institutional-grade DeFi strategies, non-custodial security, and seamless user experience.
• Hemi Labs — Hemi (https://hemi.xyz) is a modular protocol that integrates Bitcoin and Ethereum to amplify and extend the core capabilities of the two leading blockchain networks. This offers a novel perspective on blockchain interoperability and scaling by approaching Bitcoin and Ethereum as components of a single supernetwork. The result providessecurity that exceeds that of Bitcoin (“superfinality”) and new levels of blockchain programmability, portability, and potential. Hemi was co-founded by Jeff Garzik (former Bitcoin core developer) and Max Sanchez (inventor of the Proof-of-Proof consensus protocol), and is surrounded by a team of renowned blockchain engineers, strategic partners and investors.
• Movement Labs — Movement Labs is on a mission to create a global community of Move Builders, working together to improve decentralized network user experience.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Casper Labs — Casper Labs powers scalable, secure & decentralized blockchain solutions for businesses, with the most flexible and customizable architecture on the market

Portfolio highlights

• InsideDesk — Reduce AR days, boost collections, and streamline billing operations with InsideDesk's centralized revenue cycle management platform.
• CWX — CLOUDWERX provides elite engineering resources to accelerate your business.
• Lightworks — Lightworks is a Canadian consulting company that focuses on enterprise AI infrastructure and control systems. The company works with the biggest and most regulated companies in the world to plan, manage, and safeguard AI-powered systems.

Portfolio highlights

• CELL Studio — A blockchain software development company with a dedicated focus on the BTC ecosystem, committed to advancing the Nervos BTCKB initiative
• Avalon Finance — Avalon Finance is a decentralized protocol that offers a BTC liquidity mechanism for production.
• Stoneblade Entertainment — Stoneblade Entertainment operates as a publisher of strategy games.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Mytra — Supercharged Industrial Productivity with Bots, Software, and Cells
• Valar Atomics — Valar Atomics is scaling nuclear energy for heavy industrial power and clean hydrocarbon fuel production.
• Mach Industries — Delivering decentralized warfare capabilities to guarantee the defense of freedom.

Portfolio highlights

• Magma — Native liquid staking and MEV, powered by the fastest block engine in crypto. Earn yield and points, live on @Monad Mainnet.
• Rover — Bitcoin Liquid Staking on @BotanixLabs
• Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.

Portfolio highlights

• Kestra Technologies — Use declarative language to build simpler, faster, scalable and flexible workflows
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• Curvance — Curvance lets you click less and earn more. Deposit your crypto, borrow against it, and earn yield while you sleep.
• Macropod —
• Asgard Finance — Asgard helps fearless investors take confident, strategic positions in the evolving Internet Capital Markets, providing the tools, insights, and support they need to act boldly and capitalize on emerging digital opportunities.

Portfolio highlights

• Coverio — Coverio is a software company that offers enterprise-wide payroll and hiring management software for web4 companies.
• MonkeyLeague — MonkeyLeague is a video game company. They develop PC and console-based NFT games. The company offers a turn-based, play-and-earn multi-player soccer game that provides monkey NFTs of genetic composition formulated from 32 traits.
• Uniblock — Uniblock helps connect developers with Web3 using our APIs and services. Our developers use Uniblock because of how easy it is to integrate into exciting applications. Try it for free today!

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Wert — Making purchasing of NFTs seamless and not requiring users to have crypto.
• Outland — Criticism and conversations about art, technology, and NFTs

Portfolio highlights

• Kaia — Kaia is a public blockchain that utilizes Byzantine Fault Tolerance (BFT) for enhanced reliability and performance.
• Variational — Go long or short with leverage on memecoins, DEX pairs, pre-launch tokens, points markets, and more.
• Hyperdrive — Hyperdrive delivers investment growth strategies utilizing a portfolio-centered approach.

Portfolio highlights

• Quibble — Price Optimization and Revenue Management Software and Consulting For Vacation Rentals & Alternative Accommodations - We created Quibble to address the gap in the market between the simple rules-based software applications currently available and a truly science-based optimization. Quibble bundles our software with a full service offering togive our clients complete Pricing Ease of Mind. With many years of revenue management experience in the travel and hospitality industries, we know the pains and uncertainty revenue management brings. At Quibble, we aim to increase your revenue performance by engineering and implementing your custom pricing strategy while developing long-lasting partnerships.
• ClassCalc — Students can use their smartphones instead of using or buying a TI calculator, and teachers can ensure they only use the ClassCalc calculator app in class. We believe students and teachers should have a choice other than the same expensive, difficult to learn and use dedicated-purpose TI calculator they have been forced to use for decades.ClassCalc provides a multi-subject math calculator with scientific, graphing, and matrix functionality in an easy-to-use smartphone app. Teachers are able to lock down the student’s phone to only the ClassCalc app for class time, quizzes, tests… no cheating or outside distractions (social media, texting etc).
• Turno, formerly TurnoverBnB — Find now a local Airbnb cleaning service; automatically schedule your existing cleaners. Integrated with all reservations platforms and channel managers.

Portfolio highlights

• Vend Park — Unlock the true value of your parking asset with a fully digital parking access and revenue control system
• Wolf — Get all the tools and expertise you need to launch your own branded on-demand staffing platform, SpaaS and apps.
• Dataplor — Leveraging machine learning, AI, and human capital, dataplor delivers verified international places data to the world's leading companies.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Codatta — Unlock the value of your data securely and transparently. Codetta empowers freelancers to earn passive income by sharing your data with trusted entities. Take control and start earning today!
• BIO Protocol — The BIO Protocol (BIO) allows onchain scientific communities to fund, build, and co-own research and products in specific biomedical domains including lifespan, brain health, and rare disorders. BIO, founded by senior VitaDAO members, empowers worldwide communities of scientists, patients, and investors to take science into their own hands andbring solutions to life more effectively than traditional pharmaceutical companies.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Orb Labs — We make any transaction gasless and bridgeless, restore fungibility and fluidity of stablecoin, and connect onchain accounts with the offchain world.
• Flare Network — Flare is a full-stack layer 1 solution designed for data intensive use cases.

Portfolio highlights

• Natilus — We are creating a new generation of hyper-efficient blended wing body aircraft designed to make commercial aviation more sustainable and efficient, ensuring a healthier planet for future generations.
• ALKEMIO — ALKEMIO is a developer of a bio-magnetic technology intended to transform electronic waste into quality battery-grade metals.
• HEARTio — Heart I/O is a digital diagnostic startup helping emergency providers identify heart abnormalities in Pittsburgh, PA.

Portfolio highlights

• Betty — Betty is a mobile gaming entertainment company that develops the intersection of casual mobile gaming and real money online casinos.
• Manifest — Manifest is an anchor for a generation seeking direction.
• Epic Padel — EPIC is a premier padel sports management and investment company based in Arlington, VA, focused on becoming the leading operator of padel clubs across North America.

Portfolio highlights

• Soyio — Gestiona consentimiento, identidad y derechos de titulares con trazabilidad auditable. Registra actividades de tratamiento con IA. Cumple la ley 21.719.
• Regcheq — Regcheq is the developer of software as a service intended for anti-money laundering regulatory compliance management. The company offers a digital solution for AML (Anti-Money Laundering) and KYC (Know Your Customer) purposes such as digital onboarding, database check, smart policies, due diligence, client management, and reporting. This allowsclients to digitize, centralize, and automate the prevention of money laundering and comply with regulations.
• Keirón — Keiron develops software and online tools to manage healthcare services and processes. It provides digital solutions on making hospital schedules, ordering goods from pharmacies, and arranging patient information. Keiron was founded in 2019 and has operations in Mexico, Chile and Perú