Top 50 SaaS Startup Investors in Puerto Rico (November 2026)

Portfolio highlights

• Toteat — Headquarters located at Vitacura 2771, of. 504, Las Condes, Santiago de Chile
• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• BackChannel — BackChannel is an online B2B platform for inventory transactions and for buying and selling online goods.

Portfolio highlights

• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.
• Ole Insurance Group — Ole Insurance Group focuses on offering protection and well-being products and services through technology. Ole Insurance Group was founded in 2021 and was headquartered in Puerto Rico.

Portfolio highlights

• Knit — Knit is an AI-Native Research Agency that combines the rigor and expertise of a traditional agency with the speed and efficiency of AI.
• Buildforce — Amping up America's electrical workforce
• Just Women's Sports — Just Women’s Sports Inc. is a digital-first consumer media brand 100% dedicated to covering women’s sports. Through daily content including podcasts, newsletters, online content and social media, Just Women’s Sports brings you everything you need to see and know in the world of women’s sports.

Portfolio highlights

• Luminoah — Discover Luminoah Flow, the world's smallest enteral nutrition delivery system designed for your active lifestyle. Empower your nutrition journey today.
• Cloverleaf AI — Cloverleaf AI turns meetings, budgets, legislation, and purchases from 70k+ agencies into buying signals, so you reach buyers before the RFP.
• Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Portfolio highlights

• Wirelane — Driven by the mission "We empower people to move towards a clean future", Wirelane has been designing sustainable mobility since 2016 and is developing innovative complete solutions for the construction, operation, and marketing of charging infrastructure. Wirelane provides its customers with all the necessary service modules, rangingfrom cutting-edge charging technology to a digital management and billing platform, as well as comprehensive installation and operation services.
• Flashcookie — Flashcookie is an on-demand merchandise for independent artists based in Buenos Aires, Argentina.
• Solve Therapeutics — Solve Therapeutics is a biopharmaceutical company that develops Antibody Drug Conjugate and Bispecific Therapeutics. The company was founded in 2021 and is headquartered in Belmont, California.

Portfolio highlights

• Chomp — Chomp is a social network platform that focuses on on question-and-answer with prediction-based systems.
• Techdollar — Structured lending for individuals and investors at leading frontier technology companies.
• ARO Network — Turn unused internet into income. Run an ARO Node, earn $ARO tokens, and power real-time AI.

Portfolio highlights

• Inaam — inaam is an Australian impact investing app. Pick five themes, customise them and read every company you hold by name. Flat $10 a month, $100 minimum to invest.
• M-Based — M-Based develops next-generation biomaterials using mushroom, redefining sustainability in design and materials.
• Kybele's Garden — Kybele's Garden focus on algae-based bioponics and algae fermentation methods. Their differentiation strategy boosts harvest yield, source efficiency, and functional content, while improving sensory attributes and shelf life. These technologies can be used in agrifood and skin care, and integrated into existing producers' systems.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Valinor — Institutional capital solutions at the intersection of credit and blockchain

Portfolio highlights

• Cancore — Cancore operates a non-custodial cross-chain trading and settlement platform that links institutional assets on the Canton Network with public blockchain liquidity pools. The platform enables native-to-native atomic swaps across separate ecosystems via smart contracts without requiring wrapped assets, centralized custody, or third-party validator sets. Through this structure, users maintain full control of their private keys while automating and routing transaction flows across multiple public networks.
• ORO — ORO is an AI-powered DeFi companion that lets users manage, trade, stake, lend, and research crypto assets through natural-language conversations, ORO aims to simplify onchain finance by bringing portfolio management and DeFi actions into one conversational interface.
• GAEA — GAEA is a decentralized artificial intelligence training network and data infrastructure platform focused on building a comprehensive multimodal emotional database.

Portfolio highlights

• Techdollar — Structured lending for individuals and investors at leading frontier technology companies.
• Optimum — Optimum constitutes a decentralized, high-performance memory infrastructure tailored for use across various blockchains.
• Doppler Finance — Rebuilding Capital Markets for the Tokenized Era.

Portfolio highlights

• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• mogul club — Mogul is a real estate investment company specializing in crowdfunded commercial property investment and acquisition. Mogul can help you buy rental property and expand your investment portfolio.
• Spout Finance — Spout Finance is a DeFi lending protocol that allows users to borrow stablecoins by depositing tokenized U.S. stocks and ETFs as collateral. The platform operates at a 50% loan-to-value ratio and charges 0% interest on borrowings. Instead of charging interest, the protocol funds loans and generates lender yield by executing a weekly covered-call options strategy against the collateral pool. All underlying shares are held in segregated custody at a FINRA-registered, SIPC-covered U.S. broker-dealer with on-chain Proof of Reserve verification.
• Xverse — Xverse is your go-to sovereign onchain bank and Bitcoin wallet. Buy BTC, earn yield, pay with stablecoins, and borrow against your bitcoin. Download on iOS, Android & Chrome.

Portfolio highlights

• Quibble — Price Optimization and Revenue Management Software and Consulting For Vacation Rentals & Alternative Accommodations - We created Quibble to address the gap in the market between the simple rules-based software applications currently available and a truly science-based optimization. Quibble bundles our software with a full service offering togive our clients complete Pricing Ease of Mind. With many years of revenue management experience in the travel and hospitality industries, we know the pains and uncertainty revenue management brings. At Quibble, we aim to increase your revenue performance by engineering and implementing your custom pricing strategy while developing long-lasting partnerships.

Portfolio highlights

• Kapkap — PISCES88 hadir sebagai platform hiburan Slot88 terbaru 2026 dengan tema server Thailand, pilihan permainan digital, dan bisa di download melalui perangkat mobile.
• PERPTools — PERPTools combines crypto perpetual trading with activity points and risk-free market predictions.
• Matrix — Matrix is a high-performance, calldata-optimized layer-2 rollup framework engineered to scale next-generation applications within the BNB Chain ecosystem. By compressing execution data and using the BNB Chain L1 as a secure settlement layer, the protocol achieves ultra-low gas costs, predictable fees, and fast block confirmations for data-heavy workloads.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — Monitor, optimize, and grow how AI models talk about your brand. The GEO platform trusted by 500+ companies.

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• CARV — CARV enables AI Beings to live, evolve, and govern as sovereign intelligences on-chain; not as tools, but as beings that act, learn, and lead.
• Nest Wallet — A Wallet Built for Traders

Portfolio highlights

• Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients
• San Jorge Children & Women's Hospital — San Jorge Children & Women's Hospital provides health care to children and women and enables excellent services to all patients.

Portfolio highlights

• CASIMIR —
• illumicell AI — illumicell AI combines patented AI algorithms and proprietary microscopy technology to test 50x faster, 20x more effectively, empowering every healthcare provider at the point of care – not just fertility clinics – with accessible, scalable fertility diagnostics.
• SignalRank — SignalRank owns a growing asset portfolio of top performing venture backed companies. It enters at Series B by helping early stage investors maintain their ownership in their best assets. The resulting portfolio is a top decile venture performer since inception in May 2023. SignalRank finances early stage investors’ pro-rata in qualifying Series B rounds through an automated process designed for speed, high-conviction selection, and partner-aligned economics. it can decide inside 24 hours and fund in less than a week. As a result SignalRank has 300+ seed partners who invite it to partner for pro-rata financing in their fastest growing companies. It sees a high percentage of all Series B term sheets prior to close. Capital is supplied from SignalRank’s balance sheet, with no capital calls or partner IC process delays. Check size correlates with capital available. SignalRank handles SPV setup and ongoing administration, with a target of moving from partner allocation request to funding in 5 business days. 20% of the profit on each investment goes directly to partners. SignalRank creates deal-by-deal SPVs; SignalRank does not charge management fees for this partner product. The portfolio can be seen at - https://signalrank.com/signalrank-index.html

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Casper Labs — Casper Labs powers scalable, secure & decentralized blockchain solutions for businesses, with the most flexible and customizable architecture on the market

Portfolio highlights

• InsideDesk — Reduce AR days, boost collections, and streamline billing operations with InsideDesk's centralized revenue cycle management platform.
• CWX — CWX is an AI-native consultancy for regulated industries. Forward Deployed Strategists and Engineers turn AI use cases into measurable business value.
• Lightworks — Lightworks is a Canadian consulting company that focuses on enterprise AI infrastructure and control systems. The company works with the biggest and most regulated companies in the world to plan, manage, and safeguard AI-powered systems.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Mytra — Supercharged Industrial Productivity with Bots, Software, and Cells
• Valar Atomics — Valar Atomics is scaling nuclear energy for heavy industrial power and clean hydrocarbon fuel production.
• Mach Industries — Delivering decentralized warfare capabilities to guarantee the defense of freedom.

Portfolio highlights

• OpenAssets — OpenAssets builds open infrastructure and technology for digital financial systems and tokenized capital markets. The company develops standards and platforms for issuing and managing tokenized assets, digital currencies, and programmable money across major blockchains. Its solutions include tokenization-as-a-service, compliant asset issuancetools, and programmable ownership features for bonds, equities, commodities, and other assets. OpenAssets serves governments, central banks, financial institutions, and digital asset companies seeking to modernize capital markets. The organization also convenes industry alliances to define technical, policy, and governance frameworks for programmable finance.
• Superscrypt — Superscrypt is a blockchain investment firm.
• SpaceComputer — We are building the orbital root of trust: a satellite-native compute layer for confidential workloads, cryptographic services, and verifiable execution.

Portfolio highlights

• Digs — Digs is an easy-to-use collaboration software solution for professionals in residential home building that provides more efficient file storage, collaboration, and homeowner handoff for home construction projects. Try Digs for free today!
• Shoutcast Net — Stream from any device & protocol to any device & protocol. Very low latency 3 sec. AutoDJ & restream to Facebook, Twitch, YouTube included. 7 days trial!
• Midsummer Studios — Midsummer Studios is a independent, well-funded and committed to building a new kind of studio.

Portfolio highlights

• Brix — Brix Money is a blockchain platform tokenizing sovereign yield from emerging markets into programmable on-chain assets like the iTRY stablecoin, backed by Turkish money market funds for DeFi applications.
• Shodai Network — Shodai turns commitments into living agreements that encode who does what, track when it's done, and execute what happens next.
• Ethereum Institutional — Ethereum Institutional is an independent nonprofit dedicated to accelerating the institutional adoption of Ethereum, its Layer 2s, applications and overall ecosystem.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.
• NexGen Cloud — Discover NexGen Cloud's innovative AI cloud solutions designed for seamless scalability, high performance and robust security. Lead AI innovation with NexGen Cloud.

Portfolio highlights

• Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
• Shiba Inu Coin — Shiba Inu Coin is an Internet Publishing Company.
• Router Protocol — Router Protocol is a Cross Chain Bridge. Currently live on Ethereum, Polygon, and more. Building an interoperable cross chain future of the blockchain ecosystem.

Portfolio highlights

• Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
• Mauve — Fully Compliant, Non-Custodial Exchange
• Center — Start point for your next NFT app.

Portfolio highlights

• Coworked — Making enterprise change as seamless as day-to-day operations with Harmony, the headless-Al project manager. #ProjectManagement #AIProjectManagement
• furl — The world's first AI-powered collaborative experience designer
• Subject — Empower students with engaging, video-first curriculum from Subject.com for better outcomes in K-12 education. Increase graduation rates and student success.

Portfolio highlights

• Magma — Liquid Staking on Monad
• Rover — Bitcoin Liquid Staking on @BotanixLabs
• Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.

Portfolio highlights

• Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
• Flowcarbon — Flowcarbon's versatile team merges investment banking, project finance, tax credit and other financial markets expertise to streamline access to creative capital solutions for the world’s most innovative companies in the infrastructure, decarbonization, and other niche sectors. Flowcarbon is headquartered in New York, United States and wasfounded in 2021.
• IntentX — The Future of Decentralized Derivatives

Portfolio highlights

• Osmo — Giving computers a sense of smell.
• Swarm Aero — Swarm empowers small teams to mobilize thousands of uncrewed vehicles in communications-limited, contested environments.
• Artemis — Artemis is the first protective layer that is AI-native

Portfolio highlights

• OP_NET — OPNET is a Bitcoin Layer 1 metaprotocol that enables smart contracts to function directly on the Bitcoin blockchain, without the use of sidechains or Layer 2 solutions.
• Modveon — Modveon is infrastructure for trusted digital services. Verify people, connect communities and move money on one shared foundation, first deployed as Sivar in El Salvador.
• BridgePort — Interoperable network of exchanges, custodians and DeFi for optimal execution and Off-Exchange Settlement.

Portfolio highlights

• Axal — Earn competitive returns on your crypto with institutional-grade DeFi strategies, non-custodial security, and seamless user experience.
• Hemi Labs — Hemi builds Bitcoin infrastructure for money that can be moved, programmed and put to work.
• Movement Labs — Movement Labs is on a mission to create a global community of Move Builders, working together to improve decentralized network user experience.

Portfolio highlights

• CELL Studio — A blockchain software development company with a dedicated focus on the BTC ecosystem, committed to advancing the Nervos BTCKB initiative
• Avalon Finance — Avalon Finance is a decentralized protocol that offers a BTC liquidity mechanism for production.
• Stoneblade Entertainment — Stone Blade Entertainment makes Ascension, Shards of Infinity, Ascension Tactics and SolForge Fusion. Find the games, rulebooks, digital versions and news.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Natilus — We are creating a new generation of hyper-efficient blended wing body aircraft designed to make commercial aviation more sustainable and efficient, ensuring a healthier planet for future generations.
• ALKEMIO — ALKEMIO is a developer of a bio-magnetic technology intended to transform electronic waste into quality battery-grade metals.
• HEARTio — Heart I/O is a digital diagnostic startup helping emergency providers identify heart abnormalities in Pittsburgh, PA.

Portfolio highlights

• Betty — Betty is a mobile gaming entertainment company that develops the intersection of casual mobile gaming and real money online casinos.
• Manifest — Manifest is an anchor for a generation seeking direction.
• Epic Padel — EPIC is a premier padel sports management and investment company based in Arlington, VA, focused on becoming the leading operator of padel clubs across North America.

Portfolio highlights

• Nada — Finance, Invest and Bank your real estate.
• DigiBuild — Automate your construction supply chain with AI.
• Upright — Meet Upright, the good for you go-to. Our first product is a category-defining high-protein, allergen-free Instant Oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate. Each tasty cup of our oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact.

Portfolio highlights

• Qredo — Qredo is a cross-chain protocol for asset managers and traders active in the digital asset markets. Using our institution-grade, layer 2 infrastructure, investors can now hold all their crypto assets securely in one place, with unlocked access to a wide range of liquidity venues and DeFi yield opportunities.
• AuDIGENT — AuDIGENT is an audience intelligence platform that provides brands with actionable data, analytics and insights that optimize the targeting, engagement and ROI of online, mobile and social video ads while opening up new revenue streams for artists and other social influencers. AuDIGENT's platform allows brands to discover, monitor and targetaudiences that drive media performance. AuDIGENT's platform empowers artists and influencers to tap into the tools and technology needed to monetize their social influence and fan engagement. AuDIGENT's executives, data scientists, developers and operations team are in New York, Philadelphia and London. For more information visit AuDIGENT.com
• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Curvance — Curvance lets you click less and earn more. Deposit your crypto, borrow against it, and earn yield while you sleep.
• Macropod —
• Asgard Finance — Asgard helps fearless investors take confident, strategic positions in the evolving Internet Capital Markets, providing the tools, insights, and support they need to act boldly and capitalize on emerging digital opportunities.

Portfolio highlights

• Coverio — Coverio is a software company that offers enterprise-wide payroll and hiring management software for web4 companies.
• MonkeyLeague — MonkeyLeague is a video game company. They develop PC and console-based NFT games. The company offers a turn-based, play-and-earn multi-player soccer game that provides monkey NFTs of genetic composition formulated from 32 traits.
• Uniblock — Uniblock helps connect developers with Web3 using our APIs and services. Our developers use Uniblock because of how easy it is to integrate into exciting applications. Try it for free today!

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Wert — Making purchasing of NFTs seamless and not requiring users to have crypto.
• Outland — Criticism and conversations about art, technology, and NFTs

Portfolio highlights

• Kaia — Kaia is a public blockchain that utilizes Byzantine Fault Tolerance (BFT) for enhanced reliability and performance.
• Variational — Go long or short with leverage on memecoins, DEX pairs, pre-launch tokens, points markets, and more.
• Hyperdrive — Hyperdrive delivers investment growth strategies utilizing a portfolio-centered approach.

Portfolio highlights

• Quibble — Price Optimization and Revenue Management Software and Consulting For Vacation Rentals & Alternative Accommodations - We created Quibble to address the gap in the market between the simple rules-based software applications currently available and a truly science-based optimization. Quibble bundles our software with a full service offering togive our clients complete Pricing Ease of Mind. With many years of revenue management experience in the travel and hospitality industries, we know the pains and uncertainty revenue management brings. At Quibble, we aim to increase your revenue performance by engineering and implementing your custom pricing strategy while developing long-lasting partnerships.
• ClassCalc — Students can use their smartphones instead of using or buying a TI calculator, and teachers can ensure they only use the ClassCalc calculator app in class. We believe students and teachers should have a choice other than the same expensive, difficult to learn and use dedicated-purpose TI calculator they have been forced to use for decades.ClassCalc provides a multi-subject math calculator with scientific, graphing, and matrix functionality in an easy-to-use smartphone app. Teachers are able to lock down the student’s phone to only the ClassCalc app for class time, quizzes, tests… no cheating or outside distractions (social media, texting etc).
• Turno, formerly TurnoverBnB — Find now a local Airbnb cleaning service; automatically schedule your existing cleaners. Integrated with all reservations platforms and channel managers.

Portfolio highlights

• Vend Park — Unlock the true value of your parking asset with a fully digital parking access and revenue control system
• Wolf — Get all the tools and expertise you need to launch your own branded on-demand staffing platform, SpaaS and apps.
• Dataplor — Leveraging machine learning, AI, and human capital, dataplor delivers verified international places data to the world's leading companies.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Codatta — Unlock the value of your data securely and transparently. Codetta empowers freelancers to earn passive income by sharing your data with trusted entities. Take control and start earning today!
• BIO Protocol — The BIO Protocol (BIO) allows onchain scientific communities to fund, build, and co-own research and products in specific biomedical domains including lifespan, brain health, and rare disorders. BIO, founded by senior VitaDAO members, empowers worldwide communities of scientists, patients, and investors to take science into their own hands andbring solutions to life more effectively than traditional pharmaceutical companies.

Portfolio highlights

• TACEO — TACEO refers to MPC encrypted compute for Web3.
• Due — Discover our global payment platform. Powered by open, decentralised and interoperable networks.
• Freename — Register Web3 domains, custom TLDs, or import domains. Secure your digital identity today.

Portfolio highlights

• Kestra Technologies — Use declarative language to build simpler, faster, scalable and flexible workflows
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• Docker — Docker is a platform designed to help developers build, share, and run container applications. We handle the tedious setup, so you can focus on the code.
• Aleo — Welcome to Aleo. The first platform for fully private applications. Write, run, and host private applications on Aleo. The ultimate toolkit for building private applications is finally here.
• Badger DAO — A community of builders bringing Bitcoin to DeFi