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Two Sigma Ventures, VC Fund

Two Sigma Ventures

VC Fund

New York, United States

Two Sigma Ventures is an early-stage venture capital fund based in New York City investing capital and expertise in entrepreneurs leveraging data and computing to create the future. In partnership with our parent company, Two Sigma Investments, we provide entrepreneurs access to a proprietary network of experts and startup resources to give them acompetitive edge.

Total investments:
275
Last investment:
Lead investor:
25%
Fund size:
$400M
Last fund:

Last updated:

Industries Two Sigma Ventures invests in

SoftwareArtificial IntelligenceMachine LearningBiotechnologySaaS

Stages Two Sigma Ventures invests in

Series ASeedSeries BSeries CVenture - Series Unknown

Countries Two Sigma Ventures invests in

United StatesCanadaMexicoAustraliaSingapore

Round sizes

Seed $1.5M–$8MSeries A $7.5M–$70MSeries B $15M–$120M

Contacts

NameEmailPhoneSocials
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Round size

Seed
$1.5M–$8M
Series A
$7.5M–$70M
Series B
$15M–$120M

Investment Focus

Industry

  • Software 43 (16%)
  • Artificial Intelligence 28 (10%)
  • Machine Learning 20 (7%)
  • Biotechnology 16 (6%)
  • SaaS 15 (5%)
See all 196 industries →

Stage

  • Series A 63 (23%)
  • Seed 51 (19%)
  • Series B 47 (17%)
  • Series C 23 (8%)
  • Venture - Series Unknown 16 (6%)
See all 12 stages →

Country

  • United States 115 (42%)
  • Canada 1 (0%)
  • Mexico 1 (0%)
  • Australia 1 (0%)
  • Singapore 1 (0%)
See all 8 countries →

Team

NameTitleInvestmentsLinksEmail
Colin Beirne
Colin Beirne Partner
Partner Total investments: 18
Find email
David Joerg
David Joerg Managing Director
Managing Director Total investments: 7
Find email
Dusan Perovic
Dusan Perovic Partner
Partner Total investments: 13
Find email
Edward Schmidt
Edward Schmidt Venture Partner
Venture Partner Total investments: 0 Find email
Frances Schwiep
Frances Schwiep Partner
Partner Total investments: 13
Find email
See all 12 team members →

Investments

CompanyDescriptionRoundLinks
Artemis is the first protective layer that is AI-native $55M / Series A / Apr 15, 2026
Swarm Aero is an aerospace and defense company that develops large-scale unmanned aerial vehicle (UAV) swarms to operate in coordinated drone swarms for defense, logistics, and sensing missions. The company builds large uncrewed aircraft and supporting software that allow multiple drones to collaborate and perform tasks as a coordinated networkrather than as independent vehicles. These systems use onboard computing, sensors, and artificial intelligence to enable autonomous flight behaviors and collective decision-making among groups of drones. The technology platform includes aircraft hardware, swarm coordination software, and command-and-control tools that allow operators to deploy and manage large numbers of drones. A swarm node architecture integrates edge computing and distributed sensors on each vehicle so that drones can communicate with one another, share environmental data, and adapt their behavior during missions. Through this system, operators can translate mission objectives into coordinated flight patterns and task assignments executed by the swarm.Swarm Aero’s aircraft and software systems support applications such as intelligence gathering, environmental monitoring, cargo delivery, communications relay, disaster response, and security operations. The platform is designed to enable operations in environments where communications may be limited or conditions change rapidly, allowing autonomous drones to coordinate actions and adjust routes in real time. $35M / Series A / Mar 11, 2026
Osmo gives computers a sense of smell that improves the health & wellbeing of human life. $70M / Series B / Feb 04, 2026
Freeform is a 3D printing company offering metal 3D printing solutions for manufacturing companies. Freeform deploys software-defined, self-sufficient metal 3D printing factories around the world, bringing software scalability to physical production. Freeform's technology stack combines advanced sensing, real-time controls, and data-drivenlearning to produce digitally-verified, flawless parts at previously unheard-of speeds and costs. $67M / Series B / Jan 07, 2026
Highbeam is a fintech company that offers an online platform for ecommerce originators to comprehend, invest, and expand businesses. Highbeam is headqaurtered in New York, United States. $30M / Series A / Sep 09, 2025
Gameto is a biotechnology company whose mission is to redefine female reproductive health by developing therapies that improve lives.Women’s health is a vastly underserved therapeutic area. Most conditions have few treatment options, and those available often cause frequent complications and offer limited clinical benefit. Gameto aims to changethat.Gameto is committed to using cutting-edge scientific advances to deliver better solutions to patients. Using cellular engineering, they have developed a platform to produce female reproductive cell lines. They use proprietary combinations of transcription factors to reprogram hiPSCs into engineered ovarian and endometrium cell lines that mimic the functions of endogenous cells, producing and responding to all hormones. Their team of cellular engineers is using this platform to advance a portfolio of cellular therapeutics for female reproductive diseases. Gameto's first program, Fertilo, is a therapeutic for IVF and egg freezing, aiming to make the process shorter, safer and more effective. Additional applications of our platform include, an organoid of the female reproductive system, Deovo, and a cell-based therapeutic to ameliorate the health consequences of primary ovarian insufficiency and menopause, Ameno. $44M / Series C / Aug 12, 2025
Bedrock Robotics delivers enhanced autonomy to the built environment, allowing the construction sector to build at the rate that today's society requires. $80M / Series A / Jul 16, 2025
NetBox Labs makes the management of complex networks easier for operators by delivering open and composable products. The company's product NetBox Cloud offers an enterprise-grade, SaaS version of open-source NetBox. $35M / Series B / Jul 14, 2025
Cerby is the identity automation platform purpose-built to secure disconnected applications—those that fall outside the reach of traditional identity security tools. By integrating with existing IAM, IGA, and PAM systems, Cerby brings centralized access controls, automates manual security tasks, and extends governance across your entire applicationecosystem. IT and security teams gain complete visibility and control, reducing risk and operational overhead. Founded in 2020, Cerby is backed by leading investors and trusted by global enterprises. $40M / Series B / May 28, 2025
Steadily provides property and liability insurance tailored for rental property owners and investors. The company focuses on simplifying the insurance process, offering various coverage options that address the specific needs of landlords. Steadily emphasizes a user-friendly platform, enabling customers to obtain quotes and manage their policiesefficiently. The services include comprehensive coverage for property damage, liability protection, and additional endorsements to enhance policy flexibility. By streamlining the insurance experience, Steadily aims to support property owners in safeguarding their investments effectively. $30M / Series C / Apr 23, 2025
See all 275 investments →

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FAQ

What does Two Sigma Ventures invest in?

Two Sigma Ventures invests primarily in Software, Artificial Intelligence and Machine Learning startups, most often at Series A and Seed stage. Most of the 275 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is Two Sigma Ventures's check size?

Two Sigma Ventures typically joins rounds of $1.5M–$8M at Seed, $7.5M–$70M at Series A and $15M–$120M at Series B. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Two Sigma Ventures participates in.

How do I contact Two Sigma Ventures?

Public channels for Two Sigma Ventures include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Two Sigma Ventures?

The team at Two Sigma Ventures includes Colin Beirne (Partner), David Joerg (Managing Director) and Dusan Perovic (Partner), among 12 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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