Top 30 Enterprise Startup Investors in Puerto Rico in May 2026

Portfolio highlights

• Luminoah — Discover Luminoah Flow, the world's smallest enteral nutrition delivery system designed for your active lifestyle. Empower your nutrition journey today.
• Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
• Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Portfolio highlights

• Luminoah — Discover Luminoah Flow, the world's smallest enteral nutrition delivery system designed for your active lifestyle. Empower your nutrition journey today.
• Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
• Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Portfolio highlights

• ARO Network — ARO Network is a decentralized edge cloud platform focusing on power peer-to-peer content delivery.
• Silhouette Exchange — Silhouette is a privacy-focused decentralized trading protocol integrated with the Hyperliquid ecosystem.
• Impossible Cloud Network — Impossible Cloud Network (ICN) is the foundational layer for the next-generation internet — a decentralized, composable cloud infrastructure serving AI, Web3, and enterprise applications. Unlike siloed DePIN projects or centralized incumbents, ICN delivers a high-performance, permissionless platform integrating storage, compute, and networking.With $31M in total funding, enterprise-grade architecture, 1,000+ B2B clients, and 28,000+ hypernodes sold, ICN is uniquely positioned to outcompete traditional cloud services and power the future of decentralized infrastructure. ICN is community-owned, performance-optimized, and regulation-aligned — bridging real-world adoption with blockchain innovation.

Portfolio highlights

• Wirelane — Wirelane is a full service provider in the field of electric mobility. The company is currently active in 5 countries (D, F, S, NL, CH) and has experience with large industrial customers (VW, Vattenfall, Bouygues and others). In addition to their software solutions, they also offer specially developed charging stations that set standards throughthe use of advanced technology such as radar sensors and tap payment. The company works with customers from all industry sectors to develop solutions for tomorrow’s mobility needs. Wirelane is one of Europe’s leading specialist providers of hardware, software and app solutions.
• Charquiqui — Charquiqui specializes in manufacturing red meat products intended to offer cured meat snacks. It offers retail products and packages of red meat that contains beef bites, cured in natural brine, and partially dehydrated on grills.
• 13 Fronteras — Latin American Cuisine

Portfolio highlights

• Mysa — Smart Thermostats for Central HVAC, Baseboard, Mini-Split & In-Floor
• TITAN — Titan provides users with the best swap price by searching through Solana’s on-chain liquidity through trusted sources. It then deploys revolutionary routing algorithms based on cutting-edge mathematics to determine the best price a user can get when trading any token.
• Rails — Experience unparalleled speed and efficiency with Rails, your go-to platform for lightning-fast crypto perpetuals trading.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.
• NexGen Cloud — Discover NexGen Cloud's innovative AI cloud solutions designed for seamless scalability, high performance and robust security. Lead AI innovation with NexGen Cloud.

Portfolio highlights

• Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
• Shiba Inu Coin — SHIB is more than a meme it's a decentralized movement. 1.5M+ holders, 3.8M+ followers, built by the community. Join the ShibArmy.
• Router Protocol — Router Protocol is a Cross Chain Bridge. Currently live on Ethereum, Polygon, and more. Building an interoperable cross chain future of the blockchain ecosystem.

Portfolio highlights

• Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
• Mauve — Fully Compliant, Non-Custodial Exchange
• Optic — Optic monitors blockchains to reveal the origins of any NFT and how it’s been reimagined, remixed, or copied.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Wert — Making purchasing of NFTs seamless and not requiring users to have crypto.
• Outland — Criticism and conversations about art, technology, and NFTs

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Doppler Finance — Doppler Finance is a yield-earning platform that unlock earning opportunities within the XRPL ecosystem

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Casper Labs — Casper Labs powers scalable, secure & decentralized blockchain solutions for businesses, with the most flexible and customizable architecture on the market

Portfolio highlights

• Kaia — Kaia is a public blockchain that utilizes Byzantine Fault Tolerance (BFT) for enhanced reliability and performance.
• Variational — Go long or short with leverage on memecoins, DEX pairs, pre-launch tokens, points markets, and more.
• Hyperdrive — Hyperdrive delivers investment growth strategies utilizing a portfolio-centered approach.

Portfolio highlights

• Everlyn — Everlyn is a Web3 video AI model that generates a decentralized infrastructure layer for autonomous video.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.
• Cold River Games — Crystalfall is an upcoming free online action RPG with customizable skills and an endless endgame, set in a steampunk world.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• PUML Better Health — Earn cryptocurrency and get rewarded for completing gamified physical and mental health challenges. Available on both Play Store and App Store.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Codatta — Unlock the value of your data securely and transparently. Codetta empowers freelancers to earn passive income by sharing your data with trusted entities. Take control and start earning today!
• BIO Protocol — The BIO Protocol (BIO) allows onchain scientific communities to fund, build, and co-own research and products in specific biomedical domains including lifespan, brain health, and rare disorders. BIO, founded by senior VitaDAO members, empowers worldwide communities of scientists, patients, and investors to take science into their own hands andbring solutions to life more effectively than traditional pharmaceutical companies.

Portfolio highlights

• Calculum — Calculum helps you with your core business needs: Optimizing working capital, generating cash flow, and improving margins, while reducing the risk of financial supply chain disruption.
• Zion — Join our mission in creating the last platform you will ever build
• BridgePort — SaaS, Fintech, Middleware, Trading Infra

Portfolio highlights

• Magma — Magma is a decentralized liquid staking protocol built on the Monad Network, an Ethereum-compatible Layer 1 blockchain.
• Rover — Rover is a liquid staking protocol on Botanix that exchanges Bitcoin for rovBTC.
• Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.

Portfolio highlights

• Key Media — Key Media is an events and niche publishing company.
• Veridic Solutions — Veridic is a leading developer of cloud-based software. We combine talented minds with learning and innovation to solve the most complex issues. Our cloud certified engineers are uniquely positioned to serve your cloud projects
• Mobile Vascular Physicians — Mobile Vascular Physicians is a concierge vascular and interventional service (commonly called 'Special Procedures'), with a concentration in lower extremity venous and arterial disease.

Portfolio highlights

• Ballet — Ballet Crypto is a companion mobile app, which enables sending of cryptocurrency, checking market value and activating additional currencies. The use of the mobile app is completely optional, as you do not need it to receive and store your cryptocurrency safely.
• VirgoCX — We make crypto trading safe, easy, and affordable for Canadians. Buy Bitcoin, Ethereum and 60+ Cryptocurrencies with competitive pricing, Free cash in and out, instant funding, and timely customer service.
• MIDL — MIDL is a digital finance company that offers EVM compatibility, functionality of Ethereum dApps to Bitcoin users.

Portfolio highlights

• Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
• Flowcarbon — Flow Carbon uses blockchain technology to put carbon offset credits on-chain, accelerating the creativity and scalability of climate change solutions. Flow Carbon is headquartered in New York, United States and was founded in 2021.
• IntentX — The Future of Decentralized Derivatives

Portfolio highlights

• Qredo — Qredo is a cross-chain protocol for asset managers and traders active in the digital asset markets. Using our institution-grade, layer 2 infrastructure, investors can now hold all their crypto assets securely in one place, with unlocked access to a wide range of liquidity venues and DeFi yield opportunities.
• AuDIGENT — AuDIGENT is an audience intelligence platform that provides brands with actionable data, analytics and insights that optimize the targeting, engagement and ROI of online, mobile and social video ads while opening up new revenue streams for artists and other social influencers. AuDIGENT's platform allows brands to discover, monitor and targetaudiences that drive media performance. AuDIGENT's platform empowers artists and influencers to tap into the tools and technology needed to monetize their social influence and fan engagement. AuDIGENT's executives, data scientists, developers and operations team are in New York, Philadelphia and London. For more information visit AuDIGENT.com
• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Streem — Easy AR-powered remote video support & communication platform with AI data capture to get the job done from anywhere. Streem is better than being there.
• Momentum — Finally, a real solution for major gift fundraising. Powered by AI.
• Midsummer Studios — Midsummer Studios is a independent, well-funded and committed to building a new kind of studio.

Portfolio highlights

• BacAlt — Sustainable Bacterial Alernatives
• PickMyWork — Have a product for Indian Users or merchants? - Leave the headache of scaling up your product to PickMyWork.
• SignalRank — SignalRank Corporation is a FinTech company in the Venture space. It focuses on the seed stage asset class and uses data analytics to allocate capital to the best seed fund managers for their top performing companies. GPRank and CompanyRank are two proprietary algorithms it leverages to automate capital allocation. The company invests from balancesheet. Its customers are seed stage investors with outstanding companies in their portfolio.

Portfolio highlights

• Nada — Finance, Invest and Bank your real estate.
• DigiBuild — DigiBuild develops a construction management software that utilizes blockchain technology. It captures transactions from all of the different systems being utilized on the project and puts them into a filterable, searchable, and comparable project timeline to remove the waste and fraud for better data insights and decision making that will stopbudget overages.
• Upright — Meet Upright, the good for you go-to. Our first product is a category-defining high-protein, allergen-free Instant Oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate. Each tasty cup of our oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact.

Portfolio highlights

• Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.