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Top 30 Enterprise Startup Investors in Puerto Rico in April 2025

Last updated: Apr 2025 A list of 30 angel investors and VC (Venture Capital) funds that invest in Enterprise startups based in Puerto rico. We rank investors based on the number of investments they made in Enterprise companies from Puerto rico. We update this investor list every month.

Top 30 Enterprise Startup Investors in Puerto Rico in April 2025

Investor	Enterprise Puerto Rico investments
J. Hunt Holdings	2
J. Hunt Holdings	2
Parliament Capital Management	1
RockTree Capital	1
Tim Draper	1
StrongBlock	1
Housatonic Partners	1
Caladan	1
Draper Dragon	1
Jdac	1
Lecca Ventures	1
MH Ventures	1
NoLimit Holdings	1
Paramita	1
Reforge	1
Syntax Capital	1
57Blocks	1
XBTO Humla Ventures	1
DARMA Capital	1
MAKE Group	1
Acuitas Group Holdings	1
Coral	1
SVK Crypto	1
Woodstock Fund	1
Erhan Bilici	1
Betaworks Ventures	1
WAX	1
Round13 Capital	1
Lattice Capital	1
DC Ventures	1

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Investment focus

Software, Information Technology, Health Care
Seed, Funding Round, Convertible Note
United States, India, Brazil

Portfolio highlights

Luminoah — Luminoah is a research-stage business to revolutionize the enteral feeding market with a wearable system that combines durable medical equipment, consumable nutrition pouches, and remote patient monitoring to improve compliance and clinical outcomes.
Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

J. Hunt Holdings is an investment holding company that provides funds for early stage ventures. It is specialized in both domestic and international projects and investments.The company invests between $100,000 and $1,100,000 in five key industry categories, including investment services, portfolio management, accounting, and financial solutions.Mainly focused on the technology and telecommunications sectors, it also invests in the video and sensing, data center management, social media, data security, and other sectors.J. Hunt Holdings is headquartered in Washington, District of Columbia.

Investment focus

Software, Information Technology, Health Care
Seed, Convertible Note, Funding Round
United States, India, Brazil

Portfolio highlights

Luminoah — Luminoah is a research-stage business to revolutionize the enteral feeding market with a wearable system that combines durable medical equipment, consumable nutrition pouches, and remote patient monitoring to improve compliance and clinical outcomes.
Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Parliament Capital Management ("PCM") is an alternative investment management firm based in San Juan, Puerto Rico seeking value-oriented opportunities in private equity, credit and real estate.

Investment focus

Insurance, Health Care, Health Insurance
Seed
Puerto Rico

Portfolio highlights

Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients

Focused on investing in Web3 projects globally and accelerating their growth in Asian markets. Infrastructure, DeFi, Cross-chain and Bitcoin Ecosystem

Investment focus

Blockchain, Cryptocurrency, Finance
Seed, Funding Round, Series A
United States, Canada, Germany

Portfolio highlights

Magma — Magma is a decentralized liquid staking protocol built on the Monad Network, an Ethereum-compatible Layer 1 blockchain.
Fluid Protocol — Fluid Protocol is a decentralized, over-collateralized lending mechanism designed especially for Fuel Network. In order to maximize capital efficiency, Fluid offers users a safe and effective method of releasing liquidity from their collateral without having to liquidate their underlying assets.
Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.

Tim Draper is the Founding Partner of Draper Associates. He attended Harvard Business School.

Investment focus

Software, FinTech, Financial Services
Seed, Series A, Series B
United States, United Kingdom, Canada

Portfolio highlights

GALY — Saving Our Planet by Transitioning the World to Cellular Agriculture
Buupass — BuuPass is Kenya's market leader for online bus booking. We enable travelers to reserve seats and make payments in a convenient and timely way. Try BuuPass today!
Zest Protocol — Zest Protocol enables users to put their Bitcoin to work. Earn more BTC, or borrow against your BTC.

StrongBlock is a team of highly experienced blockchain, governance, security, and database technology experts. StrongBlock will exponentially increase global adoption of EOS and other governed blockchain technologies.

Investment focus

Internet
Seed
Puerto Rico

Portfolio highlights

Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Housatonic partners with exceptional entrepreneurs to build lasting companies that re-define their categories. We support management teams and their companies with transformative capital, time-tested expertise, and a deep network of seasoned executives and thought leaders.

Investment focus

Health Care, Information Technology, Software
Private Equity, Pre-Seed, Funding Round
United States, Japan, Brazil

Portfolio highlights

Key Media — Key Media is an events and niche publishing company.
Veridic Solutions — Veridic is a leading developer of cloud-based software. We combine talented minds with learning and innovation to solve the most complex issues. Our cloud certified engineers are uniquely positioned to serve your cloud projects
Mobile Vascular Physicians — Mobile Vascular Physicians is a concierge vascular and interventional service (commonly called 'Special Procedures'), with a concentration in lower extremity venous and arterial disease.

Caladan is a crypto trading firm that specializes in market-making and digital asset trading across 1000+ assets on 65+ exchanges since 2017. Learn more.

Investment focus

Financial Services, Blockchain, Cryptocurrency
Seed, Series A, Funding Round
United States, Singapore, Taiwan

Portfolio highlights

API3 — First-party blockchain oracle. Web APIs for trustless apps. Decentrally governed, quantifiably secure data feeds.
IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
Agora — Make great governance your competitive advantage. Trusted by Optimism, ENS, Uniswap and more.

We invest in the We Love Entreprenuers About Us Founded by Larry Li, Andy Tang, Bobby Chao, and Tim Draper in 2006, Draper Dragon is a cross-border venture fund that connects Silicon Valley and Asia. We have offices in Silicon Valley, Toronto, Shanghai, Hong Kong, Singapore, and Bangalore. We look for early-stage companies that would...

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Series A, Funding Round
United States, China, Singapore

Portfolio highlights

IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
Exocore — Exocore is the layer one blockchain for aggregated security.
Acre — Compounding your bitcoin

We are committed to supporting our portfolio companies at every stage of their journey and nurturing our global relationships.

Investment focus

FinTech, Internet, Payments
Seed
Estonia

Portfolio highlights

IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
Wert — Making purchasing of NFTs seamless and not requiring users to have crypto.
Outland — Criticism and conversations about art, technology, and NFTs

Lecca Ventures is a Crypto-focused Venture Capital fund investing in the web3, gaming, and blockchain technology.

Investment focus

Blockchain, Cryptocurrency, Web3
Seed, Pre-Seed
United States, Puerto Rico

Portfolio highlights

IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
Exocore — Exocore is the layer one blockchain for aggregated security.
Zkcandy — The L2 Gaming ZK Chain supercharged by iCandy Interactive and ZKsync

MH Ventures is a world class community-backed Venture Capital investing in top blockchain projects of the future

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Funding Round, Pre-Seed
United States, Singapore, United Kingdom

Portfolio highlights

Shaga — Shaga is a veteran team of blockchain, gaming, distributed systems, and networking professionals.
Exocore — Exocore is the layer one blockchain for aggregated security.
DoubleZero — DoubleZero is developing a global fiber network intended for high-performance distributed systems and blockchains. It seeks to enhance blockchain performance by establishing a dedicated physical infrastructure layer for communication.

NLH is an investment partnership focused on global crypto assets based on a deep conviction that blockchain technology will drive value creation across most business sectors over the next decade.

Investment focus

Blockchain, Cryptocurrency, Information Technology
Seed, Pre-Seed, Series A
United States, Singapore, United Kingdom

Portfolio highlights

IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
Exocore — Exocore is the layer one blockchain for aggregated security.
Infrared Finance — Infrared simplifies interacting with Proof of Liquidity with liquid staking products.

Paramita is a thesis-driven investment group.

Investment focus

Blockchain, Artificial Intelligence, Apps
Seed, Pre-Seed
United States

Portfolio highlights

IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
0G — The First Decentralized AI Operating System
Codatta — Codatta operates as an AI-powered collaboration protocol for blockchain metadata.

Reforge is an investment firm.

Investment focus

FinTech, Blockchain, Cryptocurrency
Seed
United States

Portfolio highlights

IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
Exocore — Exocore is the layer one blockchain for aggregated security.
Pharos — Pharos incorporates effective blockchain technology into real-world asset verticals and decentralized finance. Pharos Network is promoting trustless innovations that benefit asset markets and underprivileged communities, bolstering the global economy of the future and facilitating the widespread use of Web3 technologies.

Syntax Capital is a multi-strategy investment firm specializing in digital assets, with a focus on liquid and early-stage venture.

Investment focus

Web3, Blockchain, Network Security
Seed
Puerto Rico

Portfolio highlights

IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.

Bringing ideas to life. Partner with us to build and launch awesome products!

Investment focus

Blockchain, Web3, FinTech
Seed
Puerto Rico

Portfolio highlights

IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
Exocore — Exocore is the layer one blockchain for aggregated security.

XBTO Humla Ventures is a trusted digital asset innovator and investor. XBTO Humla Ventures invest in entrepreneurs with a combination of strong experience, vision and execution.

Investment focus

Bitcoin, Financial Services, Internet
Seed, Series A, Funding Round
United States, Puerto Rico

Portfolio highlights

Calculum — Calculum helps you with your core business needs: Optimizing working capital, generating cash flow, and improving margins, while reducing the risk of financial supply chain disruption.
Zion — Join our mission in creating the last platform you will ever build
Syncfy — LATAM's leading financial API.

DARMA is a global investment management firm offering expertise in digital asset risk management and blockchain technology. DARMA’s team of investment professionals has a unique combination of both traditional investment management and blockchain proficiency.

Investment focus

Internet, Software, Apps
Seed, Series A, Funding Round
Norway, Singapore, Puerto Rico

Portfolio highlights

Nahmii — Nahmii protocol was designed to solve a fundamental problem. The need for a high-performance, low-cost scaling solution. Enables a far greater number of transactions per second. Across the network, Nahmii has no limit to the number of transactions per second, with performance comparable to an optimized database. Reduces the time it takes fortransactions to be processed and gives users immediate feedback. Latency on Nahmii is measured in milliseconds. Provides general viability to all use cases, including micro-transactions.
Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.

Committed to building extraordinary homes, MAKE are a Chartered building contractor specialising in unique and premium residential projects.

Investment focus

Internet
Seed
Puerto Rico

Portfolio highlights

Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Acuitas Group Holdings is a Terren Piezer his personal holding company

Investment focus

Internet, Blockchain, Enterprise Software
Seed, Series A
Puerto Rico, Switzerland

Portfolio highlights

Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
Casper Labs — Casper Labs powers scalable, secure & decentralized blockchain solutions for businesses, with the most flexible and customizable architecture on the market

Coral DeFi is an Alternative Investment Platform focused on Digital Assets and Decentralized Finance Applications.

Investment focus

Blockchain, Software, Information Technology
Seed, Funding Round, Secondary Market
United States, Hong Kong, Puerto Rico

Portfolio highlights

Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
Flowcarbon — Flow Carbon uses blockchain technology to put carbon offset credits on-chain, accelerating the creativity and scalability of climate change solutions. Flow Carbon is headquartered in New York, United States and was founded in 2021.
IntentX — The Future of Decentralized Derivatives

SVK Crypto is an institutional venture capital firm specialising in blockchain technology. The firm's unique community-driven investment approach has created a scalable, expanding global network which generates superior deal flow. With a combined 60 years experience in investment management and management consulting, SVK Crypto will take anactive role in managing portfolio investments toward a successful exit.The firm's first fund, Cryptogon EOS LP, is a $50mn ecosystem venture fund launched in partnership with Block.One in October 2018. Block.One, creators of the EOS.IO blockchain protocol, completed the largest token generation event in history in 2018, raising in excess of $4bn. EOS.IO now represents over 85% of all transactions on public blockchains.Cryptogon EOS LP targets equity investments in early stage companies, across various industries and commercial functions, who have identified that blockchain represents a major value enhancement for their businesses.

Investment focus

Blockchain, Software, Internet
Series A, Seed, Series D
United States, Puerto Rico, United Kingdom

Portfolio highlights

Qredo — Qredo is a cross-chain protocol for asset managers and traders active in the digital asset markets. Using our institution-grade, layer 2 infrastructure, investors can now hold all their crypto assets securely in one place, with unlocked access to a wide range of liquidity venues and DeFi yield opportunities.
AuDIGENT — AuDIGENT is an audience intelligence platform that provides brands with actionable data, analytics and insights that optimize the targeting, engagement and ROI of online, mobile and social video ads while opening up new revenue streams for artists and other social influencers. AuDIGENT's platform allows brands to discover, monitor and targetaudiences that drive media performance. AuDIGENT's platform empowers artists and influencers to tap into the tools and technology needed to monetize their social influence and fan engagement. AuDIGENT's executives, data scientists, developers and operations team are in New York, Philadelphia and London. For more information visit AuDIGENT.com
Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Woodstock Fund is a multi-asset investment fund that focuses on early and growth-stage Distributed Ledger Technology (DLT) startups.

Investment focus

Blockchain, Information Technology, Cryptocurrency
Seed, Funding Round, Series A
United States, Singapore, India

Portfolio highlights

Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
Shiba Inu Coin — Shiba Inu Coin is an Internet Publishing Company.
Router Protocol — Router Protocol is a Cross Chain Bridge. Currently live on Ethereum, Polygon, and more. Building an interoperable cross chain future of the blockchain ecosystem.

Risk Management professional, experienced in Stress Testing and Capital Planning. Economist, Investment Analyst, Financial Consultant. Interested in FinTech.

Investment focus

Financial Services, FinTech, E-Commerce
Seed, Equity Crowdfunding, Pre-Seed
United States, China, India

Portfolio highlights

Nada — Finance, Invest and Bank your real estate.
DigiBuild — DigiBuild develops a construction management software that utilizes blockchain technology. It captures transactions from all of the different systems being utilized on the project and puts them into a filterable, searchable, and comparable project timeline to remove the waste and fraud for better data insights and decision making that will stopbudget overages.
Upright — Meet Upright, the good for you go-to. Our first product is a category-defining high-protein, allergen-free Instant Oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate. Each tasty cup of our oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact.

Product-focused seed-stage venture capital fund based in New York and San Francisco

Investment focus

Software, Artificial Intelligence, Information Technology
Seed, Pre-Seed, Series A
United States, United Kingdom, Canada

Portfolio highlights

Nomic AI — Nomic AI engages in improving both the explainability and accessibilty of AI.
Digs — Digs is an easy-to-use collaboration software solution for professionals in residential home building that provides more efficient file storage, collaboration, and homeowner handoff for home construction projects. Try Digs for free today!
Midsummer Studios — Midsummer Studios is a independent, well-funded and committed to building a new kind of studio.

WAX is a decentralized platform that enables anyone to operate a fully functioning virtual marketplace with zero investment in security, infrastructure, or payment processing. Developed by the founders of OPSkins, the world’s leading marketplace for online video game assets, WAX is designed to serve the 400+ million online players who alreadycollect, buy and sell.

Investment focus

Internet
Seed
Puerto Rico

Portfolio highlights

Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Founded in 2013, Round13 Capital is a leading venture and growth equity investment platform based in Toronto, Canada. The firm invests in high-potential companies across a range of sectors, with a focus on supporting their growth and development over the long term. Round13's team of experienced investors and operators bring a wealth ofexpertise and insight to every investment, helping portfolio companies to realize their full potential. With a commitment to building an enduring 100-year firm, Round13 is dedicated to creating long-term value for its investors and the companies it supports. For more information, please visit www.round13.com.

Investment focus

Software, SaaS, Internet
Seed, Series A, Series B
Canada, United States, Puerto Rico

Portfolio highlights

Mysa — Get Mysa Smart Thermostats to save money and energy with the free Mysa app! Best wifi thermostats for electric baseboard heaters. Remote access. Easy install. Utility rebates. Designed in Canada. Free shipping.
WOMBO — WOMBO is the world's best AI-powered lip sync app. Take a selfie, pick a song, and let WOMBO work its magic. Available for early access.
TITAN — Titan provides users with the best swap price by searching through Solana’s on-chain liquidity through trusted sources. It then deploys revolutionary routing algorithms based on cutting-edge mathematics to determine the best price a user can get when trading any token.

Lattice Capital helps portfolio grow by providing structure & experience to the small business development through incubation & investment.

Investment focus

Blockchain, Cryptocurrency, Software
Seed, Series A, Pre-Seed
United States, Israel, Puerto Rico

Portfolio highlights

Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
Mauve — Fully Compliant, Non-Custodial Exchange
Center — Start point for your next NFT app.

We are an early-stage focused Venture Capital and Startup advisory firm. We support and invest in entrepreneurs with the passion, drive and focus needed for success

Investment focus

Art, Information Technology, E-Commerce
Seed, Funding Round, Angel
Argentina, United States, Brazil

Portfolio highlights

Wirelane — Wirelane is a full service provider in the field of electric mobility. The company is currently active in 5 countries (D, F, S, NL, CH) and has experience with large industrial customers (VW, Vattenfall, Bouygues and others). In addition to their software solutions, they also offer specially developed charging stations that set standards throughthe use of advanced technology such as radar sensors and tap payment. The company works with customers from all industry sectors to develop solutions for tomorrow’s mobility needs. Wirelane is one of Europe’s leading specialist providers of hardware, software and app solutions.
Charquiqui — Charquiqui specializes in manufacturing red meat products intended to offer cured meat snacks. It offers retail products and packages of red meat that contains beef bites, cured in natural brine, and partially dehydrated on grills.
13 Fronteras — Latin American Cuisine

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