Top 30 Enterprise Startup Investors in Puerto Rico in May 2025
A list of 30 angel investors and VC (Venture Capital) funds that invest in Enterprise startups based in Puerto rico. We rank investors based on the number of investments they made in Enterprise companies from Puerto rico. We update this investor list every month.Top 30 Enterprise Startup Investors in Puerto Rico in May 2025
Investor | Enterprise Puerto Rico investments |
---|---|
J. Hunt Holdings | 2 |
J. Hunt Holdings | 2 |
StrongBlock | 1 |
Caladan | 1 |
Jdac | 1 |
Lecca Ventures | 1 |
MH Ventures | 1 |
NoLimit Holdings | 1 |
Paramita | 1 |
Syntax Capital | 1 |
57Blocks | 1 |
XBTO Humla Ventures | 1 |
MAKE Group | 1 |
RockTree Capital | 1 |
Tim Draper | 1 |
Housatonic Partners | 1 |
Draper Dragon | 1 |
Reforge | 1 |
DARMA Capital | 1 |
Acuitas Group Holdings | 1 |
Coral | 1 |
SVK Crypto | 1 |
Woodstock Fund | 1 |
Erhan Bilici | 1 |
Betaworks Ventures | 1 |
DC Ventures | 1 |
WAX | 1 |
Round13 Capital | 1 |
Lattice Capital | 1 |
Parliament Capital Management | 1 |
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Investment focus
- Software, Information Technology, Health Care
- Seed, Funding Round, Convertible Note
- United States, India, Brazil
Portfolio highlights
- Luminoah — Luminoah is a research-stage business to revolutionize the enteral feeding market with a wearable system that combines durable medical equipment, consumable nutrition pouches, and remote patient monitoring to improve compliance and clinical outcomes.
- Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
- Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.
J. Hunt Holdings is an investment holding company that provides funds for early stage ventures. It is specialized in both domestic and international projects and investments.The company invests between $100,000 and $1,100,000 in five key industry categories, including investment services, portfolio management, accounting, and financial solutions.Mainly focused on the technology and telecommunications sectors, it also invests in the video and sensing, data center management, social media, data security, and other sectors.J. Hunt Holdings is headquartered in Washington, District of Columbia.
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Investment focus
- Software, Information Technology, Health Care
- Seed, Convertible Note, Funding Round
- United States, India, Brazil
Portfolio highlights
- Luminoah — Luminoah is a research-stage business to revolutionize the enteral feeding market with a wearable system that combines durable medical equipment, consumable nutrition pouches, and remote patient monitoring to improve compliance and clinical outcomes.
- Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
- Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.
StrongBlock is a team of highly experienced blockchain, governance, security, and database technology experts. StrongBlock will exponentially increase global adoption of EOS and other governed blockchain technologies.
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Investment focus
- Internet
- Seed
- Puerto Rico
Portfolio highlights
- Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
Caladan is a crypto trading firm that specializes in market-making and digital asset trading across 1000+ assets on 65+ exchanges since 2017. Learn more.
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Investment focus
- Financial Services, Blockchain, Cryptocurrency
- Seed, Series A, Funding Round
- United States, Singapore, Taiwan
Portfolio highlights
- API3 — First-party blockchain oracle. Web APIs for trustless apps. Decentrally governed, quantifiably secure data feeds.
- IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
- Kaia — Kaia is a public blockchain that utilizes Byzantine Fault Tolerance (BFT) for enhanced reliability and performance.
We are committed to supporting our portfolio companies at every stage of their journey and nurturing our global relationships.
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Investment focus
- FinTech, Internet, Payments
- Seed
- Estonia
Portfolio highlights
Lecca Ventures is a Crypto-focused Venture Capital fund investing in the web3, gaming, and blockchain technology.
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Investment focus
- Blockchain, Cryptocurrency, Web3
- Seed, Pre-Seed
- United States, Puerto Rico
Portfolio highlights
MH Ventures is a world class community-backed Venture Capital investing in top blockchain projects of the future
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Investment focus
- Blockchain, Cryptocurrency, Information Technology
- Seed, Funding Round, Pre-Seed
- United States, Singapore, United Kingdom
Portfolio highlights
- Pizzapad — Pizzapad leverages cutting-edge AI technology to intelligently screen the most promising projects. Through data-driven predictions and automated due diligence, we bring you investment opportunities with high success rates.
- Gata — Gata uses data technology to develop superintelligence and to ensure its alignment with human objectives.
- Miden — Miden grants applications the power to scale with public and private transactions.
NLH is an investment partnership focused on global crypto assets based on a deep conviction that blockchain technology will drive value creation across most business sectors over the next decade.
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Investment focus
- Blockchain, Cryptocurrency, Information Technology
- Seed, Pre-Seed, Series A
- United States, Singapore, United Kingdom
Portfolio highlights
- Exocore — Exocore is the layer one blockchain for aggregated security.
- Resolv Labs — Resolv USR was born from the idea of a stablecoin independent from real-world assets risks, with yield powered by crypto money markets.
- Infrared Finance — Infrared simplifies interacting with Proof of Liquidity with liquid staking products.
Paramita is a thesis-driven investment group.
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Investment focus
- Blockchain, Artificial Intelligence, Apps
- Seed, Pre-Seed
- United States
Syntax Capital is a multi-strategy investment firm specializing in digital assets, with a focus on liquid and early-stage venture.
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Investment focus
- Web3, Blockchain, Network Security
- Seed
- Puerto Rico
Portfolio highlights
- IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
- PUML Better Health — Earn cryptocurrency and get rewarded for completing gamified physical and mental health challenges. Available on both Play Store and App Store.
Bringing ideas to life. Partner with us to build and launch awesome products!
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Investment focus
- Blockchain, Web3, FinTech
- Seed
- Puerto Rico
XBTO Humla Ventures is a trusted digital asset innovator and investor. XBTO Humla Ventures invest in entrepreneurs with a combination of strong experience, vision and execution.
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Investment focus
- Bitcoin, Financial Services, Internet
- Seed, Series A, Funding Round
- United States, Puerto Rico
Portfolio highlights
- Calculum — Calculum helps you with your core business needs: Optimizing working capital, generating cash flow, and improving margins, while reducing the risk of financial supply chain disruption.
- Zion — Join our mission in creating the last platform you will ever build
- Syncfy — LATAM's leading financial API.
Committed to building extraordinary homes, MAKE are a Chartered building contractor specialising in unique and premium residential projects.
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Investment focus
- Internet
- Seed
- Puerto Rico
Portfolio highlights
- Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
Focused on investing in Web3 projects globally and accelerating their growth in Asian markets. Infrastructure, DeFi, Cross-chain and Bitcoin Ecosystem
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Investment focus
- Blockchain, Cryptocurrency, Finance
- Seed, Funding Round, Series A
- United States, Canada, Germany
Portfolio highlights
- Magma — Magma is a decentralized liquid staking protocol built on the Monad Network, an Ethereum-compatible Layer 1 blockchain.
- Fluid Protocol — Fluid Protocol is a decentralized, over-collateralized lending mechanism designed especially for Fuel Network. In order to maximize capital efficiency, Fluid offers users a safe and effective method of releasing liquidity from their collateral without having to liquidate their underlying assets.
- Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.
Tim Draper is the Founding Partner of Draper Associates. He attended Harvard Business School.
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Investment focus
- Software, FinTech, Financial Services
- Seed, Series A, Series B
- United States, United Kingdom, Canada
Portfolio highlights
- QurieGen — QurieGen is a biotechnology company that accelerates drug discovery and development.
- Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
- Aetherflux — Abundant and renewable energy, delivered virtually anywhere
Housatonic partners with exceptional entrepreneurs to build lasting companies that re-define their categories. We support management teams and their companies with transformative capital, time-tested expertise, and a deep network of seasoned executives and thought leaders.
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Investment focus
- Health Care, Information Technology, Software
- Private Equity, Pre-Seed, Funding Round
- United States, Japan, Brazil
Portfolio highlights
- Key Media — Key Media is an events and niche publishing company.
- Veridic Solutions — Veridic is a leading developer of cloud-based software. We combine talented minds with learning and innovation to solve the most complex issues. Our cloud certified engineers are uniquely positioned to serve your cloud projects
- Mobile Vascular Physicians — Mobile Vascular Physicians is a concierge vascular and interventional service (commonly called 'Special Procedures'), with a concentration in lower extremity venous and arterial disease.
Founded by Larry Li, Andy Tang, Bobby Chao, and Tim Draper in 2006, Draper Dragon is a cross-border venture fund that connects Silicon Valley and Asia.
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Investment focus
- Blockchain, Cryptocurrency, Information Technology
- Seed, Series A, Funding Round
- United States, China, Singapore
Reforge is an investment firm.
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Investment focus
- FinTech, Blockchain, Cryptocurrency
- Seed
- United States
Portfolio highlights
- IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
- Exocore — Exocore is the layer one blockchain for aggregated security.
- Pharos — Pharos incorporates effective blockchain technology into real-world asset verticals and decentralized finance. Pharos Network is promoting trustless innovations that benefit asset markets and underprivileged communities, bolstering the global economy of the future and facilitating the widespread use of Web3 technologies.
DARMA is a global investment management firm offering expertise in digital asset risk management and blockchain technology. DARMA’s team of investment professionals has a unique combination of both traditional investment management and blockchain proficiency.
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Investment focus
- Internet, Software, Apps
- Seed, Series A, Funding Round
- Norway, Singapore, Puerto Rico
Portfolio highlights
- Nahmii — Nahmii protocol was designed to solve a fundamental problem. The need for a high-performance, low-cost scaling solution. Enables a far greater number of transactions per second. Across the network, Nahmii has no limit to the number of transactions per second, with performance comparable to an optimized database. Reduces the time it takes fortransactions to be processed and gives users immediate feedback. Latency on Nahmii is measured in milliseconds. Provides general viability to all use cases, including micro-transactions.
- Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
- Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.
Acuitas Group Holdings is a Terren Piezer his personal holding company
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Investment focus
- Internet, Blockchain, Enterprise Software
- Seed, Series A
- Puerto Rico, Switzerland
Portfolio highlights
- Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
- Casper Labs — Casper Labs powers scalable, secure & decentralized blockchain solutions for businesses, with the most flexible and customizable architecture on the market
Coral DeFi is an Alternative Investment Platform focused on Digital Assets and Decentralized Finance Applications.
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Investment focus
- Blockchain, Software, Information Technology
- Seed, Funding Round, Secondary Market
- United States, Hong Kong, Puerto Rico
Portfolio highlights
- Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
- Flowcarbon — Flow Carbon uses blockchain technology to put carbon offset credits on-chain, accelerating the creativity and scalability of climate change solutions. Flow Carbon is headquartered in New York, United States and was founded in 2021.
- IntentX — The Future of Decentralized Derivatives
SVK Crypto is an institutional venture capital firm specialising in blockchain technology. The firm's unique community-driven investment approach has created a scalable, expanding global network which generates superior deal flow. With a combined 60 years experience in investment management and management consulting, SVK Crypto will take anactive role in managing portfolio investments toward a successful exit.The firm's first fund, Cryptogon EOS LP, is a $50mn ecosystem venture fund launched in partnership with Block.One in October 2018. Block.One, creators of the EOS.IO blockchain protocol, completed the largest token generation event in history in 2018, raising in excess of $4bn. EOS.IO now represents over 85% of all transactions on public blockchains.Cryptogon EOS LP targets equity investments in early stage companies, across various industries and commercial functions, who have identified that blockchain represents a major value enhancement for their businesses.
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Investment focus
- Blockchain, Software, Internet
- Series A, Seed, Series D
- United States, Puerto Rico, United Kingdom
Portfolio highlights
- Qredo — Qredo is a cross-chain protocol for asset managers and traders active in the digital asset markets. Using our institution-grade, layer 2 infrastructure, investors can now hold all their crypto assets securely in one place, with unlocked access to a wide range of liquidity venues and DeFi yield opportunities.
- AuDIGENT — AuDIGENT is an audience intelligence platform that provides brands with actionable data, analytics and insights that optimize the targeting, engagement and ROI of online, mobile and social video ads while opening up new revenue streams for artists and other social influencers. AuDIGENT's platform allows brands to discover, monitor and targetaudiences that drive media performance. AuDIGENT's platform empowers artists and influencers to tap into the tools and technology needed to monetize their social influence and fan engagement. AuDIGENT's executives, data scientists, developers and operations team are in New York, Philadelphia and London. For more information visit AuDIGENT.com
- Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
Woodstock Fund is a multi-asset investment fund that focuses on early and growth-stage Distributed Ledger Technology (DLT) startups.
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Investment focus
- Blockchain, Information Technology, Cryptocurrency
- Seed, Funding Round, Series A
- United States, Singapore, India
Portfolio highlights
- Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
- Shiba Inu Coin — Shiba Inu Coin is an Internet Publishing Company.
- Router Protocol — Router Protocol is a Cross Chain Bridge. Currently live on Ethereum, Polygon, and more. Building an interoperable cross chain future of the blockchain ecosystem.
Risk Management professional, experienced in Stress Testing and Capital Planning.
Economist, Investment Analyst, Financial Consultant. Interested in FinTech.
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Investment focus
- Financial Services, FinTech, E-Commerce
- Seed, Equity Crowdfunding, Pre-Seed
- United States, China, India
Portfolio highlights
- Nada — Finance, Invest and Bank your real estate.
- DigiBuild — DigiBuild develops a construction management software that utilizes blockchain technology. It captures transactions from all of the different systems being utilized on the project and puts them into a filterable, searchable, and comparable project timeline to remove the waste and fraud for better data insights and decision making that will stopbudget overages.
- Upright — Meet Upright, the good for you go-to. Our first product is a category-defining high-protein, allergen-free Instant Oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate. Each tasty cup of our oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact.
Product-focused seed-stage venture capital fund based in New York and San Francisco
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Investment focus
- Software, Artificial Intelligence, Information Technology
- Seed, Pre-Seed, Series A
- United States, United Kingdom, Canada
Portfolio highlights
- Nomic AI — Nomic AI is a product studio behind popular open-source AI models and the AI data infrastructure platform Atlas.
- Digs — Digs is an easy-to-use collaboration software solution for professionals in residential home building that provides more efficient file storage, collaboration, and homeowner handoff for home construction projects. Try Digs for free today!
- Midsummer Studios — Midsummer Studios is a independent, well-funded and committed to building a new kind of studio.
We are an early-stage focused Venture Capital and Startup advisory firm. We support and invest in entrepreneurs with the passion, drive and focus needed for success
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Investment focus
- Art, Information Technology, E-Commerce
- Seed, Funding Round, Angel
- Argentina, United States, Brazil
Portfolio highlights
- Wirelane — Wirelane is a full service provider in the field of electric mobility. The company is currently active in 5 countries (D, F, S, NL, CH) and has experience with large industrial customers (VW, Vattenfall, Bouygues and others). In addition to their software solutions, they also offer specially developed charging stations that set standards throughthe use of advanced technology such as radar sensors and tap payment. The company works with customers from all industry sectors to develop solutions for tomorrow’s mobility needs. Wirelane is one of Europe’s leading specialist providers of hardware, software and app solutions.
- Charquiqui — Charquiqui specializes in manufacturing red meat products intended to offer cured meat snacks. It offers retail products and packages of red meat that contains beef bites, cured in natural brine, and partially dehydrated on grills.
- 13 Fronteras — Latin American Cuisine
WAX is a decentralized platform that enables anyone to operate a fully functioning virtual marketplace with zero investment in security, infrastructure, or payment processing. Developed by the founders of OPSkins, the world’s leading marketplace for online video game assets, WAX is designed to serve the 400+ million online players who alreadycollect, buy and sell.
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Investment focus
- Internet
- Seed
- Puerto Rico
Portfolio highlights
- Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
Founded in 2013, Round13 Capital is a leading venture and growth equity investment platform based in Toronto, Canada. The firm invests in high-potential companies across a range of sectors, with a focus on supporting their growth and development over the long term. Round13's team of experienced investors and operators bring a wealth ofexpertise and insight to every investment, helping portfolio companies to realize their full potential. With a commitment to building an enduring 100-year firm, Round13 is dedicated to creating long-term value for its investors and the companies it supports. For more information, please visit www.round13.com.
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Investment focus
- Software, SaaS, Internet
- Seed, Series A, Series B
- Canada, United States, Puerto Rico
Portfolio highlights
- Mysa — Get Mysa Smart Thermostats to save money and energy with the free Mysa app! Best wifi thermostats for electric baseboard heaters. Remote access. Easy install. Utility rebates. Designed in Canada. Free shipping.
- WOMBO — WOMBO is the world's best AI-powered lip sync app. Take a selfie, pick a song, and let WOMBO work its magic. Available for early access.
- TITAN — Titan provides users with the best swap price by searching through Solana’s on-chain liquidity through trusted sources. It then deploys revolutionary routing algorithms based on cutting-edge mathematics to determine the best price a user can get when trading any token.
Lattice Capital helps portfolio grow by providing structure & experience to the small business development through incubation & investment.
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Investment focus
- Blockchain, Cryptocurrency, Software
- Seed, Series A, Pre-Seed
- United States, Israel, Puerto Rico
Portfolio highlights
- Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
- Mauve — Fully Compliant, Non-Custodial Exchange
- Center — Start point for your next NFT app.
Parliament Capital Management ("PCM") is an alternative investment management firm based in San Juan, Puerto Rico seeking value-oriented opportunities in private equity, credit and real estate.
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Investment focus
- Insurance, Health Care, Health Insurance
- Seed
- Puerto Rico
Portfolio highlights
- Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients
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