Top 45 Software Startup Investors in Puerto Rico (September 2026)

Portfolio highlights

• Toteat — Headquarters located at Vitacura 2771, of. 504, Las Condes, Santiago de Chile
• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• BackChannel — BackChannel is an online B2B platform for inventory transactions and for buying and selling online goods.

Portfolio highlights

• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.
• Ole Insurance Group — Ole Insurance Group focuses on offering protection and well-being products and services through technology. Ole Insurance Group was founded in 2021 and was headquartered in Puerto Rico.

Portfolio highlights

• Inaam — impact investing made simple. pick your values, build a real portfolio, track where your money goes. $10/month. ASIC-regulated. built for 18-30s.
• PayToMe.co — PayToMe.co offers innovative and secure payment solutions including text-to-pay, digital invoicing, and digital checkbook services.
• Kybele's Garden — Kybele's Garden focus on algae-based bioponics and algae fermentation methods. Their differentiation strategy boosts harvest yield, source efficiency, and functional content, while improving sensory attributes and shelf life. These technologies can be used in agrifood and skin care, and integrated into existing producers' systems.

Portfolio highlights

• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• Quibble — Price Optimization and Revenue Management Software and Consulting For Vacation Rentals & Alternative Accommodations - We created Quibble to address the gap in the market between the simple rules-based software applications currently available and a truly science-based optimization. Quibble bundles our software with a full service offering togive our clients complete Pricing Ease of Mind. With many years of revenue management experience in the travel and hospitality industries, we know the pains and uncertainty revenue management brings. At Quibble, we aim to increase your revenue performance by engineering and implementing your custom pricing strategy while developing long-lasting partnerships.

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• Almanak — Almanak is a decentralized finance (DeFi) smart agent platform that harnesses the power of artificial intelligence to automate, optimize, and intelligently manage a wide range of DeFi investment strategies. It enables users to create and deploy automated DeFi trading and risk-management strategies through coordinated AI agents. It provides anenvironment where AI handles strategy coding, backtesting across thousands of Monte Carlo simulations, optimization, risk monitoring, deployment via non-custodial Safe-based multisig accounts, and real-time performance monitoring with alerting capabilities. The platform supports seamless interaction with multiple blockchains and protocols via an LLM-powered interface.Almanak targets active DeFi participants, developers building financial applications, investment professionals, and users seeking automated portfolio insights. It emphasizes enhanced automation, continuous strategy execution, and adaptive automation driven by emerging AI techniques to respond to evolving market conditions.
• Open Campus — The Open Campus is a community-driven protocol that leverages the power of blockchain and invites all to build the future of education by putting the power of learning back in the hands of educators, students, and the community.

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• CARV — CARV enables AI Beings to live, evolve, and govern as sovereign intelligences on-chain; not as tools, but as beings that act, learn, and lead.
• Nest Wallet — A Wallet Built for Traders

Portfolio highlights

• Docker — Docker is a platform designed to help developers build, share, and run container applications. We handle the tedious setup, so you can focus on the code.
• Aleo — Welcome to Aleo. The first platform for fully private applications. Write, run, and host private applications on Aleo. The ultimate toolkit for building private applications is finally here.
• Badger DAO — A community of builders bringing Bitcoin to DeFi

Portfolio highlights

• Zynk — Make Global Payments Instant
• Trace Finance — Trace Finance enables secure and swift connections between businesses and their customers through payments and automatic transaction reconciliations on a large scale, promoting integrity and efficiency.
• BIO Protocol — Biotech's new financial layer.

Portfolio highlights

• Saturn — Saturn is a decentralized Bitcoin exchange that enhances peer-to-peer non-custodial orderbooks and provides a secure trading experience.
• Nakamoto — Nakamoto is a newly established Bitcoin-native holding company and a prominent player in the cryptocurrency industry. Nakamoto Company is designed to serve as a global conglomerate focused on accelerating Bitcoin adoption and utility across capital markets.
• Blockspace Media — Blockspace Media is a media publishing agency that offers digital media content aimed at covering the Bitcoin ecosystem.

Portfolio highlights

• RED Atlas — RED Atlas offers a platform that gives real estate data and insight to people working in the property market. It provides tools that let professionals find detailed information about individual properties and trends in the market. Atlas Professional is a product on the site that gives real-time property data, news, and analytics for brokers,investors, and agents. The platform lets users search property records and generate reports that help in planning and decision-making. It makes it possible for people to filter property information and create lists that fit specific needs. The service also supports sharing property details in formats that others can review.
• Alife — Alife is building technology for both clinics and patients.
• Druid Software — Druid are the leading provider of Private 5G Networks, Private 4G Networks and LTE Private Networks with their Private Core Network Platform Raemis.

Portfolio highlights

• Neosoul — NeoSoul uses an open architecture with autonomous agents operating under user-defined constraints to link agent intelligence, deterministic capital controls, and verifiable market execution.
• ORO — ORO is an AI-powered DeFi companion that lets users manage, trade, stake, lend, and research crypto assets through natural-language conversations, ORO aims to simplify onchain finance by bringing portfolio management and DeFi actions into one conversational interface.
• Fortune Protocol — Fortune Protocol brings the age- old tradition of fortune cookies to the modern prediction market.

Portfolio highlights

• Betty — Betty is a mobile gaming entertainment company that develops the intersection of casual mobile gaming and real money online casinos.
• Manifest — Manifest is an anchor for a generation seeking direction.
• Epic Padel — EPIC is a premier padel sports management and investment company based in Arlington, VA, focused on becoming the leading operator of padel clubs across North America.

Portfolio highlights

• Kestra Technologies — Use declarative language to build simpler, faster, scalable and flexible workflows
• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• Humanos — The Risk Network for AI https://t.co/RzfFeAgNCj
• PayPerks — PayPerks operates education and rewards solutions with our partners to improve the financial capability, financial health, and overall lives of millions of Americans.
• Monax — Monax offers a platform that leverages blockchain technology and offers a contract lifecycle management tool that permits consumers to easily procure lawyer-tested agreements and stay in full control of their business contracts as well as provides permission ledgers and smart contracts, enabling the finance, insurance, and construction sectors todevelop, customize, sell and reproduce legal products.

Portfolio highlights

• Swarm Aero — Swarm empowers small teams to mobilize thousands of uncrewed vehicles in communications-limited, contested environments.
• Artemis — Artemis is the first protective layer that is AI-native
• littleBits Electronics — LittleBits is an open source library of over 60 electronic modules that snap together with magnets allows users to view, download, and share designs and make their own Bits through the use of prototypes. Deluxe kit, Smart home kit, Arduino coding kit, Synth kit, hardware development kit, and workshop set are some of the electronics learning modulesprovided by littleBits.LittleBits was launched by Ayah Bdeir in 2011 and is operated from New York, United States.

Portfolio highlights

• Foccuz — Foccuzz offers software that automates all operations by connecting multiple data sources, allowing for real-time visibility, increased efficiency, more revenue, and faster data-driven decision-making.
• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• Ábaco — Ábaco is a fintech company that offers financial services with capital, payments & platform solutions.

Portfolio highlights

• Natilus — We are creating a new generation of hyper-efficient blended wing body aircraft designed to make commercial aviation more sustainable and efficient, ensuring a healthier planet for future generations.
• ALKEMIO — ALKEMIO is a developer of a bio-magnetic technology intended to transform electronic waste into quality battery-grade metals.
• HEARTio — Heart I/O is a digital diagnostic startup helping emergency providers identify heart abnormalities in Pittsburgh, PA.

Portfolio highlights

• CELL Studio — A blockchain software development company with a dedicated focus on the BTC ecosystem, committed to advancing the Nervos BTCKB initiative
• Avalon Finance — Avalon Finance is a decentralized protocol that offers a BTC liquidity mechanism for production.
• Stoneblade Entertainment — Stoneblade Entertainment operates as a publisher of strategy games.

Portfolio highlights

• IMUA — Follow us @imua
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Valinor — Institutional capital solutions at the intersection of credit and blockchain

Portfolio highlights

• Knit — Knit is an AI-Native Research Agency that combines the rigor and expertise of a traditional agency with the speed and efficiency of AI.
• Knit — Knit helps researchers run agency-quality quant + qual research at DIY costs, by taking the most time-intensive research tasks off their plate through Researcher-Driven AI.
• Buildforce — Amping up America's electrical workforce

Portfolio highlights

• IMUA — Follow us @imua
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — The full stack AI GTM solution. We help your brand grow on autopilot.

Portfolio highlights

• Exocore — Exocore is the layer one blockchain for aggregated security.
• Exabits AI — Exabits' network of GPUs ranges from consumer-grade to H100s, offering the most cost-effective compute because we are obsessed with innovating performance.

Portfolio highlights

• Convelio — Convelio is a global logistics startup specialized in bulky, fragile and high-value items.
• Parametrix — Parametrix cloud insurance protects companies against any loss due to cloud outages. A simple, essential add-on to any cyber program.
• Sherpa.ai — Secure AI. Private Data. Sovereign Intelligence. Sherpa.ai platform enables secure distributed AI deployments across enterprises, governments, and regulat

Portfolio highlights

• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.

Portfolio highlights

• AEON — Powering #agenticeconomy #x402 | AEON is settlement layer bridging autonomous AI interactions (A2A & A2M) with real-world value flows. Backed by @yzilabs $AEON
• Slinky Network — Slinky Network provides an on-chain marketplace and payment protocol that connects AI agents and applications with third-party APIs. The company offers the SlinkyLayer platform, which wraps developer endpoints as discoverable skills and exposes them through an x402 pay-per-execution interface. Each API call triggers a non-custodial on-chainmicropayment, settling in the same request loop using networks such as Base and BNB Chain. Developers set prices, earn a defined revenue share, and receive instant payouts to their wallets without subscriptions or custodial holds. AI agents authenticate via wallet signatures, enabling autonomous, machine-to-machine access and payment without traditional logins or credit cards. The platform also records call ratings on-chain to provide portable, verifiable reputation for services.
• Shanghai Molian Technology — Shanghai Molian Technology is an intelligent agent communication infrastructure platform

Portfolio highlights

• Brix — Tokenized emerging markets yield. Trade the Macro.
• Shodai Network — The agreement layer for human and AI agents | UI + API + MCP
• Ethereum Institutional — Accelerating institutional adoption of Ethereum

Portfolio highlights

• DataRoot — DataRoot provides data science and AI solutions, helping businesses leverage data for growth and optimization.
• Conectamos — Ship with local carriers, more affordable and reliable
• Frente — Nossa missão é transformar a forma com a qual as pessoas fazem câmbio. Unimos a experiência de profissionais com carreira consolidada no mercado financeiro a uma visão inovadora e contemporânea de negócios. Tudo com a potência que a tecnologia de dados trouxe para o universo Fintech.Somos a sua parceira de câmbio mais sólida e confiável, capaz deatender às suas demandas, superando desafios cada vez maiores e mais rápidos, em um mundo em constante transformação. Nossa preocupação verdadeira com um atendimento próximo, consultivo e atencioso, além de taxas acessíveis e preços justos, complementam a experiência que oferecemos. Tudo de forma a trabalharmos para diminuir a carga burocrática e processos engessados das grandes instituições financeiras.

Portfolio highlights

• Chomp — Chomp is a social network platform that focuses on on question-and-answer with prediction-based systems.
• Techdollar — Techdollar operates a private credit platform that originates and underwrites loans secured against private company equity. The service enables late-stage startup founders, employees, and institutional investors to unlock liquidity from their shares without triggering a taxable sale or losing long-term upside.
• ARO Network — ARO Network is a decentralized edge cloud platform focusing on power peer-to-peer content delivery.

Portfolio highlights

• Healia Health — Healia is a company that provides revolutionizing health insurance for dual-income households, saving employers 85% each registered family.
• Material — Unlocking embedded power at any shape
• Poseidon Aerospace — Poseidon Aerospace develops autonomous sea-based aircraft designed to transport cargo using ground effect flight. The company produces uncrewed sea gliders that operate just above the water surface to enhance fuel efficiency and increase payload capacity.

Portfolio highlights

• Mytra — Supercharged Industrial Productivity with Bots, Software, and Cells
• Valar Atomics — Valar Atomics is scaling nuclear energy for heavy industrial power and clean hydrocarbon fuel production.
• Mach Industries — Delivering decentralized warfare capabilities to guarantee the defense of freedom.

Portfolio highlights

• Coworked — Making enterprise change as seamless as day-to-day operations with Harmony, the headless-Al project manager. #ProjectManagement #AIProjectManagement
• furl — Remediating vulnerabilities at scale.
• Subject — Empower students with engaging, video-first curriculum from Subject.com for better outcomes in K-12 education. Increase graduation rates and student success.

Portfolio highlights

• Fina — Fina Partner offers a platform to manage and automate key processes for SMEs, including inventory control and financial management.
• Ruvo — Cacao is a fintech platform that allows Brazilians to receive, store, spend, and withdraw USD instantly.
• Upper — Transforming cross-border e-commerce in Latin America

Portfolio highlights

• Ric — Ric delivers $10,000 to you within 48-hours of policy activation. An affordable way to take charge of your recovery after a severe rainfall for $14/Month.
• Monterra — Licensed PEs deliver stamped electrical plans for tenant improvements, EV charging, and battery storage. Preliminary design in 48 hours, stamped package in days.
• Homeostasis — Homeostasis is a CO2 removal and utilization company building a novel pipeline that outputs raw materials for industrial applications.

Portfolio highlights

• Curvance — Curvance lets you click less and earn more. Deposit your crypto, borrow against it, and keep earning the whole time.
• Macropod —
• Asgard Finance — We help fearless investors take structured positions in Internet Capital Markets

Portfolio highlights

• Finite Pay — Finite Pay aims to unify Africa's payment systems to enhance cross-border trade. Our platform offers multi-currency accounts for easy local and international transactions, while our treasury services mitigate foreign exchange risks. With insights into the African market, we help businesses optimize payment processes and expand. We also supportglobal companies in making payments to and from Africa, ensuring a smooth multi-currency experience. By partnering strategically, we are establishing the financial infrastructure needed for economic growth and financial inclusion across the continent. Join us in connecting Africa through seamless payments!
• Flint — Introducing a new battery technology designed for sustainable energy solutions. Explore our innovation and its impact on the future of energy.
• Mycorium Biotech — Growing the next generation of materials

Portfolio highlights

• Beldex — Beldex is a private ecosystem consisting of decentralized applications. The Beldex privacy coin (BDX) is a utility coin of the Beldex private ecosystem.
• Fortune Protocol — Fortune Protocol brings the age- old tradition of fortune cookies to the modern prediction market.
• Perceptron Network — AI agents that learn, earn, and reward trust. Perceptron powers a decentralized mesh of reputation and revenue. Perceptron Network is the first AI-powered system where interactions drive growth and earn real rewards.

Portfolio highlights

• Soyio — Gestiona consentimiento, identidad y derechos de titulares con trazabilidad auditable. Registra actividades de tratamiento con IA. Cumple la ley 21.719.
• Regcheq — Regcheq is the developer of software as a service intended for anti-money laundering regulatory compliance management. The company offers a digital solution for AML (Anti-Money Laundering) and KYC (Know Your Customer) purposes such as digital onboarding, database check, smart policies, due diligence, client management, and reporting. This allowsclients to digitize, centralize, and automate the prevention of money laundering and comply with regulations.
• Keirón — Keiron develops software and online tools to manage healthcare services and processes. It provides digital solutions on making hospital schedules, ordering goods from pharmacies, and arranging patient information. Keiron was founded in 2019 and has operations in Mexico, Chile and Perú

Portfolio highlights

• Alpaca — Alpaca API allows developers and businesses to build apps, embed investing, and trade algorithms
• Stackpack — AI-powered visibility and control for your company's vendors and contracts - fully synced with your financial software. Try it risk-free for 30 days today.
• Harmonic — Building Mathematical Superintelligence

Portfolio highlights

• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.

Portfolio highlights

• Airstack — Every day there are millions of blockchain transactions. Airstack makes sense of them.
• Intuition — Intuition provides decentralized infrastructure, developer tools, and applications enabling the creation of an open, flexible knowledge graph enhancing the quality and availability of social knowledge.
• Cube Exchange — Cube is the world's fastest crypto exchange. Built by and for traders, Cube is the most liquid, secure and advanced cryptocurrency exchange.

Portfolio highlights

• Hyperion — Join the Hyperion waitlist today to access the only bank account your business will ever need.

Portfolio highlights

• OpenAssets — OpenAssets builds open infrastructure and technology for digital financial systems and tokenized capital markets. The company develops standards and platforms for issuing and managing tokenized assets, digital currencies, and programmable money across major blockchains. Its solutions include tokenization-as-a-service, compliant asset issuancetools, and programmable ownership features for bonds, equities, commodities, and other assets. OpenAssets serves governments, central banks, financial institutions, and digital asset companies seeking to modernize capital markets. The organization also convenes industry alliances to define technical, policy, and governance frameworks for programmable finance.
• Superscrypt — Superscrypt is a blockchain investment firm.
• SpaceComputer — SpaceComputer uses satellites to create a secure blockchain system that resists cyberattacks and physical tampering.

Portfolio highlights

• Axal — Earn competitive returns on your crypto with institutional-grade DeFi strategies, non-custodial security, and seamless user experience.
• Hemi Labs — Hemi (https://hemi.xyz) is a modular protocol that integrates Bitcoin and Ethereum to amplify and extend the core capabilities of the two leading blockchain networks. This offers a novel perspective on blockchain interoperability and scaling by approaching Bitcoin and Ethereum as components of a single supernetwork. The result providessecurity that exceeds that of Bitcoin (“superfinality”) and new levels of blockchain programmability, portability, and potential. Hemi was co-founded by Jeff Garzik (former Bitcoin core developer) and Max Sanchez (inventor of the Proof-of-Proof consensus protocol), and is surrounded by a team of renowned blockchain engineers, strategic partners and investors.
• Movement Labs — Movement Labs is on a mission to create a global community of Move Builders, working together to improve decentralized network user experience.

Portfolio highlights

• WINT — Wint Water Intelligence mitigates water-related risks via AI & IoT-based leak detection including auto valve shut-off to protect your property
• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• Quantum Art — Quantum Art develops scalable, multi-core quantum computers with advanced trapped ion qubits and multi-qubit gates, accelerating breakthroughs in AI, finance, and materials science.