Top 20 Medical Startup Investors in Portugal (June 2026)

Portfolio highlights

• PLUTOS — We are here to make sure that your Puppy gets the best treat! PLUTOS were created specifically for dogs to have fun. Find out our dog healthy chews.
• SCUBIC — SCUBIC is a developer of a cloud-based analytics platform. They were designed to help water utilities and industries improve the management of water supply systems. They combine water management, energy efficiency techniques, data science, hydraulics, and software engineering in order to deliver impactful solutions that improve systems andprocesses. They are specialized services that account for the energy usage in homes, service buildings, or industrial plants.
• KeepIt Energy — KeepIt - KeepIt will place an energy storage technology on the market and thus contribute to a successful energy transition. This technology, which can potentially be used in different market segments, from home solar systems in developing countries to grid support in developed countries, will make an important contribution to harmonisingproduction and consumption in a world that runs on electricity produced entirely from renewable sources. KeepIt is a spin-off from the Faculty of Sciences of the University of Lisbon, stemming from the doctoral work in which its founding partners were involved.

Portfolio highlights

• Equall — Equall offers legal AI systems to help companies and lawyers evaluate and control risk.
• DOJO AI — Dojo AI is pioneering the Marketing Operating System (MOS) category, providing challenger brands with enterprise-grade marketing infrastructure. Its proprietary technology combines real-time market intelligence, specialized AI agents, and automated workflow orchestration in one unified platform.The Dojo MOS enables marketing teams to run theirentire operation - from market research and strategy to content creation and campaign execution - through a single, intelligent system. The platform features a proprietary graph engine for real-time market intelligence, marketing-specific language models, and autonomous AI agents trained for specialized marketing tasks.Built for challenger brands looking to compete more effectively, Dojo eliminates the need for multiple point solutions and reduces dependency on external agencies. The platform continuously learns and optimizes, providing companies with compounding advantages as they scale their marketing operations.
• DareData —

Portfolio highlights

• Caresyntax — Caresyntax is the only enterprise-scale surgical data solution you need to make surgery smarter, safer, and more profitable.
• ENYO Pharma — ENYO Pharma is a biopharmaceutical company incorporated in Jan, 2014, by four scientists of the Infectiology Research Center in Lyon, France, and three seeding partners (2 privates and 1 public).The company is based in the Infectiology Center of Lyonbiopôle in Lyon, France and maintains tight collaborations with the seminal Inserm team and theBSL4 laboratory Inserm-Jean Mérieux.ENYO Pharma has licensed several Inserm patents issued from the discoveries of the founding scientists and developed a unique platform for the identification of intracellular therapeutic targets and molecules.The company is developing treatments against the most important viruses and is thriving to become a global leader in anti-virals. Research and Development is currently focused on human infecting viruses, with the first two programs being dedicated to the treatment of severe and seasonal flu and chronic hepatitis B. The company plans to conduct its molecules to Phase II clinical trials.
• Inflammatix — Inflammatix develops rapid point of care diagnostic tests by reading the immune system, and resolves major clinical health challenges.

Portfolio highlights

• Count — Explore, refactor, and share your data at warp speed.
• Passport — Passport is the modern shipping carrier for international ecommerce that helps direct-to-consumer brands ship their products internationally.
• Belo — Crypto for everyone, everyday

Portfolio highlights

• Veniam — Transfer 10x more data for your video telematics, fleet operations, industrial IoT or connected vehicles.
• Noxus — At Spot, we're crafting the operating system for tomorrow's workforce, harnessing AI to streamline influencer marketing. Our platform empowers agencies, businesses, and content creators to collaborate effectively and reach audiences with ease.
• Infraspeak — Infraspeak is an Intelligent CMMS Software that brings outstanding flexibility, connectivity and intelligence to your operations.

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• hOS — hOS is an early-stage AI technology company.
• Kirontech — Detect & manage wasteful practices
• RunSafe Security — Secure embedded systems with RunSafe Security's runtime cybersecurity protection, integrating build-time defenses without affecting performance.

Portfolio highlights

• Biosurfit — At biosurfit they are working to shape the future of in-vitro diagnostic testing. They want health providers to have all the necessary information to make the best possible diagnostic and treatment decision when they are with their patients

Portfolio highlights

• Perfood — Perfood is a digital therapeutic startup that identifies what actions need to take on a personalized level, to prevent or fight diseases. Using sensors, lab results, and holistic analyses, they derive therapeutic angles and deliver them in a slick, easy-to-use way, making them accessible for all patients. They call this approach digitaltherapeutics. A digital solution that is just as effective as a drug. But without side effects.
• Brainomix — Since launching as a spin-out from the University of Oxford in 2010, Brainomix has developed award-winning, AI-powered imaging biomarkers, assisting physicians across the world to make better life-saving decisions. Brainomix seminal product, e-Stroke is a collection of tools that use state-of-the-art AI algorithms to support doctors by providingreal-time interpretation of brain scans to help guide treatment and transfer decisions for stroke patients, allowing more patients to get the right treatment, in the right place, at the right time.
• Rinri Therapeutics — Rinri Therapeutics has been founded on pioneering research into auditory stem cells led by Professor Marcelo Rivolta at the University of Sheffield.

Portfolio highlights

• Sonendo — Sonendo developing innovative technologies to transform dentistry by Saving Teeth Through Sound Science®. The GentleWave® System shows significant improvements in clinical efficacy and practice efficiency when compared to standard root canal treatment.1,2, 3 Sonendo is the parent company of TDO® Software, the developer of the most widely usedendodontic practice management software in the world, designed to simplify practice workflow. TDO software seamlessly integrates practice management, imaging, social media, referral reporting, CBCT imaging, and offers built-in communication with the GentleWave System.
• resTORbio — Restore Beauty - Rethink Bio
• Caris Life Sciences — Caris fulfills the promise of precision oncology through advanced laboratory testing, including tumor profiling and blood-based cancer diagnostics.

Portfolio highlights

• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.
• BIMINI Biotech — BIMINI Biotech is a startup that develops innovative therapeutic strategies for oncology. It is developing therapeutic strategies that target the growth hormone receptor (GHR) and its interaction with insulin-like growth factor 1 (IGF-1) for oncology, metabolic diseases, and aging.The company was founded in 2019 and is based in Leiden, TheNetherlands.
• MAIR PHARMACEUTICALS — Mair Pharmaceutical creates innovative processes and produces well-known unique substances for pharmaceutical and biopharmaceutical firms worldwide.

Portfolio highlights

• Laigo Bio — Laigo Bio uses E3 ligase internalization to precisely degrade membrane proteins linked to autoimmune and inflammatory disorders.
• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.

Portfolio highlights

• LOQR — Increase your business and reduce costs with the best AI-Powered Journey-as-a-Service provider for financial institutions.
• Connected — Connected is a startup that offers affordable connecting humans, unleashing a new wave of IoT-based business models and contributing to bridge the digital gap.
• Sound Particles — A CGI-like software for Sound Design, capable of using particle systems to generate thousands of sounds in a virtual 3D world

Portfolio highlights

• Sdui — Sdui is the solution for mobile communication in schools. With amazingly easy features for messaging, timetables and a wide range of third party integrations, the app digitizes processes and reduces administrative effort. Within two years, Sdui has reached hundreds of institutions and grown a serious reputation in the educational market.
• envelio — We are driving forward the energy transition with our smart grid solutions for grid operators. Get information now and plan smart!
• Atriva Therapeutics — Therapies against viral infections. First-in-class host-targeting therapies to treat respiratory viral infections, including COVID-19 and influenza.

Portfolio highlights

• CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!

Portfolio highlights

• Algori — Improving FMCG growth with the fastest and most granular insights from 45,000 shoppers in Spain
• Manie —
• Musiversal — Record your music in real time with world-class session musicians, vocalists, producers and audio engineers

Portfolio highlights

• Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.

Portfolio highlights

• Criam — CRIAM stands for Chemical Reaction and Image Analysis for Mobility. We are a Medtech startup born in January 2016 focused in the Point-of-Care diagnostic segment. Our mission is to provide fast, affordable and in-situ blood test analysis to empower people with instant information about their well-being and health conditions. With our device as aplatform approach we will be able to monitor, control and contain diseases worldwide.
• MemoryWell — MemoryWell is a digital platform for storytelling that brings the skills of professional writers to the challenge of helping elders tell their life story. With MemoryWell+, you can build a collaborative timeline around that story, adding photos, videos, letters and documents. Everyone has a story, let us help you capture it.

Portfolio highlights

• CUZIN — Providing a surprisingly human shopping experience. Trusted and secure. Millions of domains to choose from.
• Living Models — Living Models is concentrating on this field by employing AI methods on biological data, especially in plant science, where enhancing crop yield and resilience is becoming crucial as global agriculture is impacted by climatic challenges.
• Infiction labs — SPARC 1.2 is a solar panel robotic cleaning system designed and developed by Infiction Labs Pvt Ltd for commercial solar plants.

Portfolio highlights

• Qalea —
• Dealcar — DEALCAR is a company that digitalizes the used car market through a SaaS platform, enabling fully digital transactions. This platform creates a network effect benefiting dealers, partners, and customers. • Dealers: Increase revenue by selling extra products and boost sales by reducing turnover time. • Partners: Distribute products at the pointof sale without marketing expenses, lowering operational costs. • Consumers: Purchase a used car easily in just three steps, enjoying a smooth, trusted process similar to renting but with the benefits of owning a car.
• KomboAI — Supercharge your CRM and close more deals with KomboAI Find the right leads, engage them with purpose and improve your skills every day. Book a Demo See Kombo in Action Over 1000+ sales reps are already using KomboAI during their job Join the sales revolution today Find the right leads Receive every day new leads