Top 30 Biotechnology Startup Investors in Portugal (June 2026)

Portfolio highlights

• PLUTOS — We are here to make sure that your Puppy gets the best treat! PLUTOS were created specifically for dogs to have fun. Find out our dog healthy chews.
• SCUBIC — SCUBIC is a developer of a cloud-based analytics platform. They were designed to help water utilities and industries improve the management of water supply systems. They combine water management, energy efficiency techniques, data science, hydraulics, and software engineering in order to deliver impactful solutions that improve systems andprocesses. They are specialized services that account for the energy usage in homes, service buildings, or industrial plants.
• KeepIt Energy — KeepIt - KeepIt will place an energy storage technology on the market and thus contribute to a successful energy transition. This technology, which can potentially be used in different market segments, from home solar systems in developing countries to grid support in developed countries, will make an important contribution to harmonisingproduction and consumption in a world that runs on electricity produced entirely from renewable sources. KeepIt is a spin-off from the Faculty of Sciences of the University of Lisbon, stemming from the doctoral work in which its founding partners were involved.

Portfolio highlights

• Veniam — Transfer 10x more data for your video telematics, fleet operations, industrial IoT or connected vehicles.
• Noxus — At Spot, we're crafting the operating system for tomorrow's workforce, harnessing AI to streamline influencer marketing. Our platform empowers agencies, businesses, and content creators to collaborate effectively and reach audiences with ease.
• Infraspeak — Infraspeak is an Intelligent CMMS Software that brings outstanding flexibility, connectivity and intelligence to your operations.

Portfolio highlights

• Pollen — Pollen is developing a universal battery-swapping network for mopeds and motorcycles, enabling riders to quickly exchange depleted batteries for fully charged ones, reducing downtime and supporting efficient, scalable electric mobility in urban environments.
• Wio Capital — Wio Capital is a wealthtech company that builds an AI-powered wealth management platform for financial advisors, offices, and bankers.
• Spacebackend — Spacebackend is redefining how aerospace teams handle mission-critical integration. Our platform, Lynapse, is an AI-powered system integration environment designed for engineers-in-the-loop. We empower software integration and AIT/AIV teams to bridge the gap from hardware interface to flight-ready software - starting in the design phase andcontinuing through end-to-end integration.By decoupling software readiness from physical hardware and leveraging AI to automate the implementation of complex interfaces, we reduce integration effort from years to days. Lynapse uses AI to convert complex ICD documentation into digital models, automatically producing, testing, and validating platform-agnostic source code.Our workflow ensures every line of code is deterministic, engineer-approved, and fully traceable from documentation to deployment. Whether you are generating platform-agnostic code from scratch or validating existing flight software against a digital ICD model, Lynapse exposes failures and readiness gaps early - when it matters most. Build integration readiness today.

Portfolio highlights

• Equall — Equall offers legal AI systems to help companies and lawyers evaluate and control risk.
• DOJO AI — Dojo AI is pioneering the Marketing Operating System (MOS) category, providing challenger brands with enterprise-grade marketing infrastructure. Its proprietary technology combines real-time market intelligence, specialized AI agents, and automated workflow orchestration in one unified platform.The Dojo MOS enables marketing teams to run theirentire operation - from market research and strategy to content creation and campaign execution - through a single, intelligent system. The platform features a proprietary graph engine for real-time market intelligence, marketing-specific language models, and autonomous AI agents trained for specialized marketing tasks.Built for challenger brands looking to compete more effectively, Dojo eliminates the need for multiple point solutions and reduces dependency on external agencies. The platform continuously learns and optimizes, providing companies with compounding advantages as they scale their marketing operations.
• DareData —

Portfolio highlights

• Vaxdyn — Preventing the next global health crisis Our mission is to prevent and alleviate the global health crisis caused by the pathogenic bacteria resistant to ant ...
• CellmAbs — Pharmaceutical Company, Biotechnology
• Adapttech — Adapttech is a biomedical company that uses innovative, smart and wearable technologies to deliver full adaptation and comfort to people with physical limitations.

Portfolio highlights

• hOS — hOS is an early-stage AI technology company.
• Kirontech — Detect & manage wasteful practices
• RunSafe Security — Secure embedded systems with RunSafe Security's runtime cybersecurity protection, integrating build-time defenses without affecting performance.

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• Zen8 — Explore Connected Swim Training at zwim.com. Smart Swim Trainer + data + immersive game = real swim power. Train at home, get faster in the water. Join the waitlist now.
• LoopOS — LoopOS is a comprehensive Circular Economy ERP system designed to optimize and streamline multiple processes including buybacks, returns, trade-ins, repairs, and consumer-to-consumer transactions. It focuses on providing tools to measure the impact of the activities.
• PFx Biotech — PFx Biotech transforms food through bioinnovation by creating sustainable and nutritional alternative protein solutions.

Portfolio highlights

• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• Abtrace — Abtrace is an automated, self-learning care system where we can provide personalised care, delivered at population scale - where predictive, preventative and proactive approaches keep people healthy and out of hospital.
• sheerME — SheerME is Revolutionising the way people find, book, and pay for their Wellness and Beauty services powered by a benefit-based walletOur approach is based on Discovery, Transaction & Reward to create more online visibility, reach, conversion into new business, loyalty, and frequency through our wallet and cashback ecosystem, to all ourpartners in the beauty and wellness sectors.This made us a fresh and different option in this sector where there are mainly SaaS players, and we bring marketplace with no monthly fee, only a commission for business sent through our owned and partner channels.
• ChemiTek — Certified & sustainable solutions for industrial maintenance. We have the solutions you need!

Portfolio highlights

• Rivia — Integrated Clinical Trial Intelligence. Drive therapeutic evaluation and trial management with real-time insights.
• io Health — Io Health Technologies LLC provides AI-driven tools for home health documentation and workflow automation in healthcare.
• Sober Sidekick — Gamified peer to peer support

Portfolio highlights

• CUZIN — Providing a surprisingly human shopping experience. Trusted and secure. Millions of domains to choose from.
• Living Models — Living Models is concentrating on this field by employing AI methods on biological data, especially in plant science, where enhancing crop yield and resilience is becoming crucial as global agriculture is impacted by climatic challenges.
• Infiction labs — SPARC 1.2 is a solar panel robotic cleaning system designed and developed by Infiction Labs Pvt Ltd for commercial solar plants.

Portfolio highlights

• SKETCHAR.io — Sketchar is the ultimate AR drawing app for art creation, learning to draw, and collaborating with 12M people. Try now!
• Candlestick.io — Advanced crypto trading with smart money tracking and DeFi analytics
• Space DOTS — SKY-I, by SpaceDOTS, transforms fragmented space environmental data into unified, mission-critical intelligence that enables confident decision-making across the entire space mission lifecycle.

Portfolio highlights

• Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Criam — CRIAM stands for Chemical Reaction and Image Analysis for Mobility. We are a Medtech startup born in January 2016 focused in the Point-of-Care diagnostic segment. Our mission is to provide fast, affordable and in-situ blood test analysis to empower people with instant information about their well-being and health conditions. With our device as aplatform approach we will be able to monitor, control and contain diseases worldwide.
• MemoryWell — MemoryWell is a digital platform for storytelling that brings the skills of professional writers to the challenge of helping elders tell their life story. With MemoryWell+, you can build a collaborative timeline around that story, adding photos, videos, letters and documents. Everyone has a story, let us help you capture it.

Portfolio highlights

• LOQR — Increase your business and reduce costs with the best AI-Powered Journey-as-a-Service provider for financial institutions.
• Connected — Connected is a startup that offers affordable connecting humans, unleashing a new wave of IoT-based business models and contributing to bridge the digital gap.
• Sound Particles — A CGI-like software for Sound Design, capable of using particle systems to generate thousands of sounds in a virtual 3D world

Portfolio highlights

• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.
• BIMINI Biotech — BIMINI Biotech is a startup that develops innovative therapeutic strategies for oncology. It is developing therapeutic strategies that target the growth hormone receptor (GHR) and its interaction with insulin-like growth factor 1 (IGF-1) for oncology, metabolic diseases, and aging.The company was founded in 2019 and is based in Leiden, TheNetherlands.
• MAIR PHARMACEUTICALS — Mair Pharmaceutical creates innovative processes and produces well-known unique substances for pharmaceutical and biopharmaceutical firms worldwide.

Portfolio highlights

• DigiLens — DigiLens is an innovator in holographic waveguide display technology for extended reality (XR).DigiLens has developed a patented optical platform and photopolymer technology that delivers best-in-class solutions using a unique, low-cost contact-copy manufacturing process. DigiLens enables OEM partners to design and build XR-enabled devices for theglobal automobile, enterprise, consumer, avionics, and military industries.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.
• Applecrumby & Fish — Applecrumby & Fish is an online and offline baby store that offers various brands of baby products available both locally and internationally. The baby products are classified under the categories: bath and skincare, food and health, feeding, baby gear, diapers and potty, playroom, maternity, and school.Putto, Brush Baby, Tommee Tippee,Hot-Kid, Nordic Naturals, Annie’s Organic, Zoli, Munchkin, Avent, Clevamama, Attitude, Potette Plus, The First Years, Renova, Peaceable Kingdom, Mega Bloks, Emma-Jane, MooGoo, Stephen Joseph, and Thinkbaby are some of the brands available in Applecrumby & Fish’s stores.Applecrumby & Fish was founded in 2011 and is based in Selangor, Malaysia.

Portfolio highlights

• BIZAY / 360imprimir — • Bizay has empowered more than 1 Million SMB’s to grow their businesses during the last 5 years.• Bizay is a tech-based B2B Marketplace for made-to-order products. Running a fabless business model (no capex), it leverages on the idle capacity of production partners to meet the needs of the SMB’s.• Started on printing, packaging, textile andprofessional products and now applying the same model in furniture, food and 3D printing (amongst others).• 360imprimir / 360onlineprint - rebranded to Bizay - Your bussiness your way - to reflect the unlimited product categories. • Bizay is the customer facing brand (the SMB’s do not meet the production partners) and its tech platform manages the production by: o Using data and algorithms to aggregate different orders and to decide in which suppliers to produce them, driving huge efficiency and speed gains. o Enabling full tracking of the orders in the different production partners and automating pre-production processes.• Bizay differentiates themselves from other players by offering: o Online configuration of the products (options to customize and personalize). o Competitive pricing for small and medium orders (similar price per unit as for large orders), 48 hours of delivery time (instead of several weeks) and guaranteed quality (customer-facing brand ensuring high quality levels). o Integrated value chain in a single offer (on-demand design services provided by external providers).• Originally selling in Portugal, Spain, Brazil and México, the company raised B round of 18m€ one year ago (communicated in April) in order to launch new countries.• 17 new countries were launched in 2019 simultaneously (including DE, FR, UK and USA).• In 2019, 8 months of trading in the new countries confirm: o Competitiveness pricing of their offer in all the market. o Market deepness and sound acquisition metrics.
• Promptly — Health Analytics Patient Report Outcomes, Health Care, Value based health
• NVision Imaging Technologies — NVision Imaging Technologies is leveraging advances in quantum physics to enable the first routine, convenient and affordable use of Magnetic Resonance Imaging (MRI) for assessing early patient response to cancer treatment at the metabolic level.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• MindProber — Not all impressions are created equal. Understand the emotional impact of your content. Learn about Mediaprobe - Next-gen media measurement.
• Habit — Habit's mission is to bring context and meaningfulness to the way insurance is sold. We connect brands with insurers to enable the best way to distribute insurance - on digital.

Portfolio highlights

• Algori — Improving FMCG growth with the fastest and most granular insights from 45,000 shoppers in Spain
• Manie —
• Musiversal — Record your music in real time with world-class session musicians, vocalists, producers and audio engineers

Portfolio highlights

• Sonendo — Sonendo developing innovative technologies to transform dentistry by Saving Teeth Through Sound Science®. The GentleWave® System shows significant improvements in clinical efficacy and practice efficiency when compared to standard root canal treatment.1,2, 3 Sonendo is the parent company of TDO® Software, the developer of the most widely usedendodontic practice management software in the world, designed to simplify practice workflow. TDO software seamlessly integrates practice management, imaging, social media, referral reporting, CBCT imaging, and offers built-in communication with the GentleWave System.
• resTORbio — Restore Beauty - Rethink Bio
• Caris Life Sciences — Caris fulfills the promise of precision oncology through advanced laboratory testing, including tumor profiling and blood-based cancer diagnostics.

Portfolio highlights

• Laigo Bio — Laigo Bio uses E3 ligase internalization to precisely degrade membrane proteins linked to autoimmune and inflammatory disorders.
• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.

Portfolio highlights

• Flow Eighteen38 — FairJourney Biologics is your end-to-end antibody discovery and biologics partner, offering world-class mammalian display, cell-line development and protein production services to accelerate therapeutic pipelines.

Portfolio highlights

• Jiseki Health — Jiseki is built on the belief that families and communities need and deserve a safety net, and to have peace of mind when things go wrong. We provide access and delivery of key advice, help, products and services through highly scalable SMS technology, powered by a combination of professionals and AI, and sold as a portable life benefit package..Text #help to 543210, to discover Jiseki services.
• Biome Analytics — Biome is an analytic applications that help cardiovascular teams do their best work. It helps forward thinking hospitals profitably transition and thrive in the new world of healthcare. During COVID-19, Biome has focused on assessing hospital capacity.
• NEXT Life Sciences — NEXT Life Sciences is developing the revolutionary Plan A™ procedure to bring the only scientifically proven technology in the category - Vasalgel® - to market.