Top 35 Biotechnology Startup Investors in Portugal (June 2026)

Portfolio highlights

• Azulfy — Real-time pollution monitoring for EU municipalities. Satellite-based environmental compliance tools for local governments and smart cities.
• PLUTOS — We are here to make sure that your Puppy gets the best treat! PLUTOS were created specifically for dogs to have fun. Find out our dog healthy chews.
• Hostels HUB — Hostels HUB is a hostel developer that is looking for opportunities both in city as leisure locations around Portugal.

Portfolio highlights

• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.
• Movvo — The Movvo platform delivers smart business intelligence solutions for owners and operators of retail and commercial real estate that turns data into improved retail performance and better value engineering decisions. The platform combines consumer behaviour wireless sensor technology and digests other public and private datasets, enhancing theunderstanding of the data by applying machine learning to provide fast and easy interpretation of this data delivering insights and rapid scenario-planning. Whether it is measuring ROI or reporting KPI's, the Movvo platform has these bases covered. Where it comes into its own is via the application of machine learning Want to easily prepare a leasing pack that maximises the rental value, what to create additional incremental value from asset investment decisions, want to know the impact of changing the tenant from apparel retailer to food & beverage? The Movvo platform can deliver prescriptive intelligence and more.
• Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.

Portfolio highlights

• Pollen — Pollen is developing a universal battery-swapping network for mopeds and motorcycles, enabling riders to quickly exchange depleted batteries for fully charged ones, reducing downtime and supporting efficient, scalable electric mobility in urban environments.
• Wio Capital — Wio Capital is a wealthtech company that builds an AI-powered wealth management platform for financial advisors, offices, and bankers.
• Spacebackend — Spacebackend is redefining how aerospace teams handle mission-critical integration. Our platform, Lynapse, is an AI-powered system integration environment designed for engineers-in-the-loop. We empower software integration and AIT/AIV teams to bridge the gap from hardware interface to flight-ready software - starting in the design phase andcontinuing through end-to-end integration.By decoupling software readiness from physical hardware and leveraging AI to automate the implementation of complex interfaces, we reduce integration effort from years to days. Lynapse uses AI to convert complex ICD documentation into digital models, automatically producing, testing, and validating platform-agnostic source code.Our workflow ensures every line of code is deterministic, engineer-approved, and fully traceable from documentation to deployment. Whether you are generating platform-agnostic code from scratch or validating existing flight software against a digital ICD model, Lynapse exposes failures and readiness gaps early - when it matters most. Build integration readiness today.

Portfolio highlights

• Laigo Bio — Laigo Bio uses E3 ligase internalization to precisely degrade membrane proteins linked to autoimmune and inflammatory disorders.
• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.

Portfolio highlights

• Equall — Equall offers legal AI systems to help companies and lawyers evaluate and control risk.
• DOJO AI — Dojo AI is pioneering the Marketing Operating System (MOS) category, providing challenger brands with enterprise-grade marketing infrastructure. Its proprietary technology combines real-time market intelligence, specialized AI agents, and automated workflow orchestration in one unified platform.The Dojo MOS enables marketing teams to run theirentire operation - from market research and strategy to content creation and campaign execution - through a single, intelligent system. The platform features a proprietary graph engine for real-time market intelligence, marketing-specific language models, and autonomous AI agents trained for specialized marketing tasks.Built for challenger brands looking to compete more effectively, Dojo eliminates the need for multiple point solutions and reduces dependency on external agencies. The platform continuously learns and optimizes, providing companies with compounding advantages as they scale their marketing operations.
• DareData —

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• Zen8 — Explore Connected Swim Training at zwim.com. Smart Swim Trainer + data + immersive game = real swim power. Train at home, get faster in the water. Join the waitlist now.
• Nutrium — Nutrium is the most up-to-date nutrition software for dietitians and nutritionists to manage their nutrition business with nutritional assessment, meal planning and progress tracking.
• PFx Biotech — PFx Biotech transforms food through bioinnovation by creating sustainable and nutritional alternative protein solutions.

Portfolio highlights

• hOS — hOS is an early-stage AI technology company.
• Kirontech — Detect & manage wasteful practices
• RunSafe Security — Secure embedded systems with RunSafe Security's runtime cybersecurity protection, integrating build-time defenses without affecting performance.

Portfolio highlights

• Vaxdyn — Preventing the next global health crisis Our mission is to prevent and alleviate the global health crisis caused by the pathogenic bacteria resistant to ant ...
• CellmAbs — Pharmaceutical Company, Biotechnology
• Adapttech — Adapttech is a biomedical company that uses innovative, smart and wearable technologies to deliver full adaptation and comfort to people with physical limitations.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Algori — Improving FMCG growth with the fastest and most granular insights from 45,000 shoppers in Spain
• Musiversal — Record your music in real time with world-class session musicians, vocalists, producers and audio engineers
• Punto Health — AI-Powered, Personalised Support for Every Patient and Family

Portfolio highlights

• Sonendo — Sonendo developing innovative technologies to transform dentistry by Saving Teeth Through Sound Science®. The GentleWave® System shows significant improvements in clinical efficacy and practice efficiency when compared to standard root canal treatment.1,2, 3 Sonendo is the parent company of TDO® Software, the developer of the most widely usedendodontic practice management software in the world, designed to simplify practice workflow. TDO software seamlessly integrates practice management, imaging, social media, referral reporting, CBCT imaging, and offers built-in communication with the GentleWave System.
• Crown Bioscience — Crown Bioscience is an expert preclinical contract research organization providing oncology services and preclinical cancer models for drug development. Crown Biocience brings clarity to drug discovery worldwide, helping companies solve today's most pressing problems in immuno-oncology, oncology, cardiovascular, and metabolic diseases.
• Aspen Neuroscience — personalized cell therapy Starts with you Learn More about our technology

Portfolio highlights

• Jiseki Health — Jiseki is built on the belief that families and communities need and deserve a safety net, and to have peace of mind when things go wrong. We provide access and delivery of key advice, help, products and services through highly scalable SMS technology, powered by a combination of professionals and AI, and sold as a portable life benefit package..Text #help to 543210, to discover Jiseki services.
• Biome Analytics — Biome is an analytic applications that help cardiovascular teams do their best work. It helps forward thinking hospitals profitably transition and thrive in the new world of healthcare. During COVID-19, Biome has focused on assessing hospital capacity.
• NEXT Life Sciences — NEXT Life Sciences is developing the revolutionary Plan A™ procedure to bring the only scientifically proven technology in the category - Vasalgel® - to market.

Portfolio highlights

• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• NobodyWho — NobodyWho is an inference engine that lets you run LLMs locally on any device
• FION Energy — FION Energy GmbH is a Berlin-based company at the forefront of the clean energy transition, specializing in advanced energy storage and management solutions for industrial businesses. Their technology helps companies optimize energy use, reduce costs, enhance grid stability, and accelerate decarbonization by providing economically viable storagesystems tailored to each customer's needs. FION supports grid operators by enabling efficient orchestration of energy consumption and generation, contributing to a more stable and sustainable energy future. They offer personalized consulting, rapid installation, and continuous optimization of energy storage performance to maximize cost savings and flexibility.
• Bubble Robotics — Bubble Robotics, a company focused on building advanced underwater robots. Their mission is to create autonomous ocean robotics for scalable subsea data collection to improve offshore efficiency and marine resource stewardship. By combining advanced resident robotics, seamless autonomy, and AI-powered analytics, they aim to revolutionize oceanexploration and operations, making the oceans safer, smarter, and more sustainable.

Portfolio highlights

• OmniumAI — OmniumAI are developing CibusAI to revolutionise traditional food reformulation.

Portfolio highlights

• Hope Care Health — Hope Care is a digital health company that combines services, products, and cutting-edge technology platforms to enable the delivery of Social and Health Care without barriers.
• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.
• CryoTherapeutics — CryoTherapeutics is focusing on the development, demonstration of clinical benefit, and early-stage commercialization of a proprietary cryotherapy system for use in the treatment of coronary artery disease that causes heart attacks. The safety and efficacy of cryoenergy in the cardiovascular system has been demonstrated and CryoTherapeutics intendsto extend the benefits of cryoenergy to the problem of diseased coronary arteries.

Portfolio highlights

• sheerME — SheerME is Revolutionising the way people find, book, and pay for their Wellness and Beauty services powered by a benefit-based walletOur approach is based on Discovery, Transaction & Reward to create more online visibility, reach, conversion into new business, loyalty, and frequency through our wallet and cashback ecosystem, to all ourpartners in the beauty and wellness sectors.This made us a fresh and different option in this sector where there are mainly SaaS players, and we bring marketplace with no monthly fee, only a commission for business sent through our owned and partner channels.
• Cargofive — Cargofive is the digital solution that will allow your freight forwarder to access to maritime rates from different providers in one place.
• Bling Energy — Bling Energy is a startup that focuses on providing more efficient and sustainable energy solutions, mostly through solar panels.

Portfolio highlights

• Silentvector — Biotechnology applied to agriculture. Research, development, innovation, and production of bioprotectants, biofertilizers, biostimulants, and nutrients of biological origin.

Portfolio highlights

• CUZIN — Providing a surprisingly human shopping experience. Trusted and secure. Millions of domains to choose from.
• Andromeda Robotics — At Andromeda, our personalised robot companions are helping Australian aged care teams bring joy and connection to residents to improve wellbeing.
• Infiction labs — SPARC 1.2 is a solar panel robotic cleaning system designed and developed by Infiction Labs Pvt Ltd for commercial solar plants.

Portfolio highlights

• Zoolife — Giving 4 billion animal lovers access to wildlife animals up-close, through live 24/7 user-controlled cameras, with behind-the-scenes zookeeper talks and feeding times daily from the best ethical zoos & animal sanctuaries.
• Pageport — Effortlessly convert more leads by automatically sending unique, personalized video pages to everyone.
• Polkadot — Polkadot is a dedicated community that envisions a web where users own their digital identities and data, restoring their authority.

Portfolio highlights

• Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Promptly — Health Analytics Patient Report Outcomes, Health Care, Value based health
• Healthplus.ai — Healthplus.ai enables surgical care professionals to be more proactive towardcs patients, care and outcome; predicting infections before they are normally diagnosed.
• NVision Imaging Technologies — NVision Imaging Technologies is leveraging advances in quantum physics to enable the first routine, convenient and affordable use of Magnetic Resonance Imaging (MRI) for assessing early patient response to cancer treatment at the metabolic level.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!

Portfolio highlights

• Flow Eighteen38 — FairJourney Biologics is your end-to-end antibody discovery and biologics partner, offering world-class mammalian display, cell-line development and protein production services to accelerate therapeutic pipelines.

Portfolio highlights

• pleez — Pleez offers Restaurant's an optimisation of their menu within Delivery Platforms, so that they can have a revenue increase up to 25%.
• Volup — Volup is a premium food delivery app that partners exclusively with top-tier chefs and restaurants.
• Relive — Relive is empowering the next generation of real estate entrepreneurs, with a mobile app that allows them to work for themselves, from anywhere, while saving time and earning commissions faster.

Portfolio highlights

• MindProber — Not all impressions are created equal. Understand the emotional impact of your content. Learn about Mediaprobe - Next-gen media measurement.
• Habit — Habit's mission is to bring context and meaningfulness to the way insurance is sold. We connect brands with insurers to enable the best way to distribute insurance - on digital.

Portfolio highlights

• Abtrace — Abtrace is an automated, self-learning care system where we can provide personalised care, delivered at population scale - where predictive, preventative and proactive approaches keep people healthy and out of hospital.
• sheerME — SheerME is Revolutionising the way people find, book, and pay for their Wellness and Beauty services powered by a benefit-based walletOur approach is based on Discovery, Transaction & Reward to create more online visibility, reach, conversion into new business, loyalty, and frequency through our wallet and cashback ecosystem, to all ourpartners in the beauty and wellness sectors.This made us a fresh and different option in this sector where there are mainly SaaS players, and we bring marketplace with no monthly fee, only a commission for business sent through our owned and partner channels.
• ChemiTek — Certified & sustainable solutions for industrial maintenance. We have the solutions you need!

Portfolio highlights

• TEKEVER — The Tekever Group is a provider of innovative technologies in Software, Aerospace, Defence and Security Markets.
• Connected — Connected is a startup that offers affordable connecting humans, unleashing a new wave of IoT-based business models and contributing to bridge the digital gap.
• CorPower Ocean — CorPower Ocean AB was founded in 2009 to develop high efficiency Wave Energy Converters (WECs).CorPower's Wave Energy Converters deliver five times higher annual energy output per ton of device compared to previously known wave power solutions. The step-change improvement in performance and efficiency allows a Cost-of-Energy that cancompete with offshore wind. The products are currently in pilot with Iberdrola. CorPower has assembled a team with extensive experience in energy generation, design and manufacturing of production equipment, system engineering as well as the market expertise to allow us to continue transforming the technology of tomorrow into renewable energy applications of today.

Portfolio highlights

• DigiLens — DigiLens is an innovator in holographic waveguide display technology for extended reality (XR).DigiLens has developed a patented optical platform and photopolymer technology that delivers best-in-class solutions using a unique, low-cost contact-copy manufacturing process. DigiLens enables OEM partners to design and build XR-enabled devices for theglobal automobile, enterprise, consumer, avionics, and military industries.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.
• Applecrumby & Fish — Applecrumby & Fish is an online and offline baby store that offers various brands of baby products available both locally and internationally. The baby products are classified under the categories: bath and skincare, food and health, feeding, baby gear, diapers and potty, playroom, maternity, and school.Putto, Brush Baby, Tommee Tippee,Hot-Kid, Nordic Naturals, Annie’s Organic, Zoli, Munchkin, Avent, Clevamama, Attitude, Potette Plus, The First Years, Renova, Peaceable Kingdom, Mega Bloks, Emma-Jane, MooGoo, Stephen Joseph, and Thinkbaby are some of the brands available in Applecrumby & Fish’s stores.Applecrumby & Fish was founded in 2011 and is based in Selangor, Malaysia.

Portfolio highlights

• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• Navidence — Navidence provides a transformative Real World Evidence (RWE) Design platform that enables organizations to efficiently adapt to the ever-increasing ecosystem of Real World Data (RWD) sources. The company unlocks the power of Computable Operational Definitions (CODefs) for RWE Design and RWD Assessment. Navidence's RWE Sherpa platform offerstools to streamline the process of defining an RWE study's data, making it easier for researchers to conduct their studies in the age of data.
• Rivia — Integrated Clinical Trial Intelligence. Drive therapeutic evaluation and trial management with real-time insights.
• Sober Sidekick — Gamified peer to peer support

Portfolio highlights

• Criam — CRIAM stands for Chemical Reaction and Image Analysis for Mobility. We are a Medtech startup born in January 2016 focused in the Point-of-Care diagnostic segment. Our mission is to provide fast, affordable and in-situ blood test analysis to empower people with instant information about their well-being and health conditions. With our device as aplatform approach we will be able to monitor, control and contain diseases worldwide.
• tuTECHÔ — tuTECHÔ is an innovative social enterprise born with the purpose of contributing to the eradication of homelessness in Spain.
• MemoryWell — MemoryWell is a digital platform for storytelling that brings the skills of professional writers to the challenge of helping elders tell their life story. With MemoryWell+, you can build a collaborative timeline around that story, adding photos, videos, letters and documents. Everyone has a story, let us help you capture it.