Top 30 Biotechnology Startup Investors in Portugal in May 2026

Portfolio highlights

• AddVolt — AddVolt is a technology based company that tackles markets where there is a high potential for diesel costs reduction through the generation of solar and kinetic energy, while other secondary savings are generated (e.g. maintenance).
• Hephaesnus — Hephaesnus is an industrial technology startup dedicated to the development of products and technologies for forest firefighting.
• Floating Particle — Floating Particle is a technology and innovation company that drives an innovative solution for waste management and clean energy. Floating Particle specializes in IoT, Big Data and Machine Learning to provide cutting-edge technology to the customers.

Portfolio highlights

• HiJiffy — Increase direct bookings and upselling with HiJiffy's AI-powered communication solutions for hospitality.
• Noxus — At Spot, we're crafting the operating system for tomorrow's workforce, harnessing AI to streamline influencer marketing. Our platform empowers agencies, businesses, and content creators to collaborate effectively and reach audiences with ease.
• Infraspeak — Infraspeak is an Intelligent CMMS Software that brings outstanding flexibility, connectivity and intelligence to your operations.

Portfolio highlights

• Dealcar — DEALCAR is a company that digitalizes the used car market through a SaaS platform, enabling fully digital transactions. This platform creates a network effect benefiting dealers, partners, and customers. • Dealers: Increase revenue by selling extra products and boost sales by reducing turnover time. • Partners: Distribute products at the pointof sale without marketing expenses, lowering operational costs. • Consumers: Purchase a used car easily in just three steps, enjoying a smooth, trusted process similar to renting but with the benefits of owning a car.
• nuuEnergy — nuuEnergy is a tech-enabled solution aiming to revolutionize the heat pump installation industry. By leveraging technology and industry expertise, we streamline the purchasing and installation process. Our unique approach, refinanced through innovative strategies, promotes a self-reliant and carbon-neutral lifestyle for all our customers.
• Relive — Relive is empowering the next generation of real estate entrepreneurs, with a mobile app that allows them to work for themselves, from anywhere, while saving time and earning commissions faster.

Portfolio highlights

• Cintoo — Cintoo is essential for BIM to bridge the gap between your physical and virtual worlds.
• Automaise — Radically improve your customer care operations by focusing where the volume is and helping your agents do a better job.
• Sword Health — Sword delivers AI Care with clinical oversight to prevent pain, support recovery, and promote whole-body health. Trusted by employers and health plans.

Portfolio highlights

• Vaxdyn — Preventing the next global health crisis Our mission is to prevent and alleviate the global health crisis caused by the pathogenic bacteria resistant to ant ...
• CellmAbs — Pharmaceutical Company, Biotechnology
• Adapttech — Adapttech is a biomedical company that uses innovative, smart and wearable technologies to deliver full adaptation and comfort to people with physical limitations.

Portfolio highlights

• hOS — hOS is an early-stage AI technology company.
• Kirontech — Detect & manage wasteful practices
• RunSafe Security — Secure embedded systems with RunSafe Security's runtime cybersecurity protection, integrating build-time defenses without affecting performance.

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• D-Orbit — End-to-end services for the New Space industry, including platform engineering, launch and deployment, and decommissioning.
• Sensei — We are the leading European provider of autonomous stores, with an AI-powered solution to build efficient operations and deliver a seamless shopping experience.
• Tryp.com — Find the best travel deals with artificial intelligence. Our algorithm connects flights, trains, and buses for perfect trips with matching hotels.

Portfolio highlights

• BetterPic — Forget expensive, complicated photoshoots. Get your professional headshots on the go, with 8 selfies/casual photos in less than an hour. High-quality customer service, top data privacy, and a clear money-back guarantee policy.
• Nilo — Nilo is a collaborative 3D platform that works across desktop, mobile, Discord, and Telegram. It combines generative AI with world-building tools, allowing users to generate assets, characters, animations, and code from natural language or drawings. The result: a radically simplified creation experience that lowers the barrier to entry andaccelerates how quickly new ideas can be built, tested, and shared.It’s creation at the speed of culture: whether spinning up a game inspired by today’s viral sound, turning a group chat joke into a playable world or crafting a custom hangout, Nilo transforms imagination into interaction — instantly and collaboratively.Nilo’s key features include:Text-to-3D generation: Create characters, environments, and code from prompts or images. Browser-Based: Nilo runs entirely in your browser - no installs, no downloads, no friction. Voice-enabled coding: A built-in AI-powered code editor that supports spoken commands and natural language for playful, social programming. Real-time multiplayer: Co-create and play with friends instantly.Nilo was founded in April 2024, bringing together veterans from Fortnite, Twitch, YouTube, Snapchat, Microsoft, Adobe, Blizzard, VRChat, Rec Room, and major VFX projects such as Avatar and Star Wars.
• specter automation — Construction is the second least digitized sector in the world with 96% of all data being unused. Although detailed planning data is created upfront, a lack of suitable digital tools prevents its transfer to the construction site. SPECTER’s web-based construction management software uniquely incorporates the core components of constructionplanning, reducing the organizational burden on construction management and helping to meet project timelines and budgets.

Portfolio highlights

• Windward Bio — Windward Bio is a clinical-stage, drug development company committed to improving outcomes for people living with advanced immunological diseases.
• Microtide Biotechnology — Microtide Biotechnology is an innovative company specializing in the field of in vivo cell therapy. The company is dedicated to advancing next-generation biomedical technologies that harness the body’s own cellular mechanisms for disease treatment, focusing on developing safe, effective, and precise therapeutic solutions to improve patient outcomesand redefine the future of regenerative medicine.
• Sparrow Pharmaceuticals — Sparrow Pharmaceuticals is an emerging clinical-stage biopharmaceutical company developing novel, targeted therapies for disorders of corticosteroid excess.

Portfolio highlights

• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.
• Mair Therapeutics — Mair Therapeutics main goal is finding and creating a small-molecule ion channel activator to treat Parkinson's disease, a preclinical drug discovery business.
• MAIR PHARMACEUTICALS — Mair Pharmaceutical creates innovative processes and produces well-known unique substances for pharmaceutical and biopharmaceutical firms worldwide.

Portfolio highlights

• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.

Portfolio highlights

• Flow Eighteen38 — FairJourney Biologics is your end-to-end antibody discovery and biologics partner, offering world-class mammalian display, cell-line development and protein production services to accelerate therapeutic pipelines.

Portfolio highlights

• DigiLens — DigiLens is an innovator in holographic waveguide display technology for extended reality (XR).DigiLens has developed a patented optical platform and photopolymer technology that delivers best-in-class solutions using a unique, low-cost contact-copy manufacturing process. DigiLens enables OEM partners to design and build XR-enabled devices for theglobal automobile, enterprise, consumer, avionics, and military industries.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.
• Applecrumby & Fish — Applecrumby & Fish is an online and offline baby store that offers various brands of baby products available both locally and internationally. The baby products are classified under the categories: bath and skincare, food and health, feeding, baby gear, diapers and potty, playroom, maternity, and school.Putto, Brush Baby, Tommee Tippee,Hot-Kid, Nordic Naturals, Annie’s Organic, Zoli, Munchkin, Avent, Clevamama, Attitude, Potette Plus, The First Years, Renova, Peaceable Kingdom, Mega Bloks, Emma-Jane, MooGoo, Stephen Joseph, and Thinkbaby are some of the brands available in Applecrumby & Fish’s stores.Applecrumby & Fish was founded in 2011 and is based in Selangor, Malaysia.

Portfolio highlights

• BIZAY / 360imprimir — • Bizay has empowered more than 1 Million SMB’s to grow their businesses during the last 5 years.• Bizay is a tech-based B2B Marketplace for made-to-order products. Running a fabless business model (no capex), it leverages on the idle capacity of production partners to meet the needs of the SMB’s.• Started on printing, packaging, textile andprofessional products and now applying the same model in furniture, food and 3D printing (amongst others).• 360imprimir / 360onlineprint - rebranded to Bizay - Your bussiness your way - to reflect the unlimited product categories. • Bizay is the customer facing brand (the SMB’s do not meet the production partners) and its tech platform manages the production by: o Using data and algorithms to aggregate different orders and to decide in which suppliers to produce them, driving huge efficiency and speed gains. o Enabling full tracking of the orders in the different production partners and automating pre-production processes.• Bizay differentiates themselves from other players by offering: o Online configuration of the products (options to customize and personalize). o Competitive pricing for small and medium orders (similar price per unit as for large orders), 48 hours of delivery time (instead of several weeks) and guaranteed quality (customer-facing brand ensuring high quality levels). o Integrated value chain in a single offer (on-demand design services provided by external providers).• Originally selling in Portugal, Spain, Brazil and México, the company raised B round of 18m€ one year ago (communicated in April) in order to launch new countries.• 17 new countries were launched in 2019 simultaneously (including DE, FR, UK and USA).• In 2019, 8 months of trading in the new countries confirm: o Competitiveness pricing of their offer in all the market. o Market deepness and sound acquisition metrics.
• Promptly — Health Analytics Patient Report Outcomes, Health Care, Value based health
• NVision Imaging Technologies — NVision Imaging Technologies is leveraging advances in quantum physics to enable the first routine, convenient and affordable use of Magnetic Resonance Imaging (MRI) for assessing early patient response to cancer treatment at the metabolic level.

Portfolio highlights

• Zen8 — Explore Connected Swim Training at zwim.com. Smart Swim Trainer + data + immersive game = real swim power. Train at home, get faster in the water. Join the waitlist now.
• LoopOS — LoopOS is a comprehensive Circular Economy ERP system designed to optimize and streamline multiple processes including buybacks, returns, trade-ins, repairs, and consumer-to-consumer transactions. It focuses on providing tools to measure the impact of the activities.
• PFx Biotech — PFx Biotech transforms food through bioinnovation by creating sustainable and nutritional alternative protein solutions.

Portfolio highlights

• Jiseki Health — Jiseki is built on the belief that families and communities need and deserve a safety net, and to have peace of mind when things go wrong. We provide access and delivery of key advice, help, products and services through highly scalable SMS technology, powered by a combination of professionals and AI, and sold as a portable life benefit package..Text #help to 543210, to discover Jiseki services.
• Biome Analytics — Biome is an analytic applications that help cardiovascular teams do their best work. It helps forward thinking hospitals profitably transition and thrive in the new world of healthcare. During COVID-19, Biome has focused on assessing hospital capacity.
• NEXT Life Sciences — NEXT Life Sciences is developing the revolutionary Plan A™ procedure to bring the only scientifically proven technology in the category - Vasalgel® - to market.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• pleez — Pleez offers Restaurant's an optimisation of their menu within Delivery Platforms, so that they can have a revenue increase up to 25%.
• Volup — Volup is a premium food delivery app that partners exclusively with top-tier chefs and restaurants.
• Relive — Relive is empowering the next generation of real estate entrepreneurs, with a mobile app that allows them to work for themselves, from anywhere, while saving time and earning commissions faster.

Portfolio highlights

• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• Abtrace — Abtrace is an automated, self-learning care system where we can provide personalised care, delivered at population scale - where predictive, preventative and proactive approaches keep people healthy and out of hospital.
• sheerME — SheerME is Revolutionising the way people find, book, and pay for their Wellness and Beauty services powered by a benefit-based walletOur approach is based on Discovery, Transaction & Reward to create more online visibility, reach, conversion into new business, loyalty, and frequency through our wallet and cashback ecosystem, to all ourpartners in the beauty and wellness sectors.This made us a fresh and different option in this sector where there are mainly SaaS players, and we bring marketplace with no monthly fee, only a commission for business sent through our owned and partner channels.
• ChemiTek — Certified & sustainable solutions for industrial maintenance. We have the solutions you need!

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!

Portfolio highlights

• Datamonk — AI-powered PACS migration platform that automates secure and fast transfers of medical imaging data. Migrate up to 10TB per day and use AI agents for data validation and quality assurance.
• io Health — Io Health Technologies LLC provides AI-driven tools for home health documentation and workflow automation in healthcare.
• Sober Sidekick — Gamified peer to peer support

Portfolio highlights

• MindProber — Not all impressions are created equal. Understand the emotional impact of your content. Learn about Mediaprobe - Next-gen media measurement.
• Habit — Habit's mission is to bring context and meaningfulness to the way insurance is sold. We connect brands with insurers to enable the best way to distribute insurance - on digital.

Portfolio highlights

• CUZIN — Providing a surprisingly human shopping experience. Trusted and secure. Millions of domains to choose from.
• CLIQ — We understand firsthand the impact of social isolation and the longing for genuine human connection. CLIQ was born from a vision to address this issue and to fundamentally transform the way that we meet new people and form connections.
• Infiction labs — SPARC 1.2 is a solar panel robotic cleaning system designed and developed by Infiction Labs Pvt Ltd for commercial solar plants.

Portfolio highlights

• Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Make Sunsets — We create global cooling by launching reflective, biodegradable, high-altitude clouds. main side effect: more vivid sunsets;)
• Polkadot — Polkadot is a dedicated community that envisions a web where users own their digital identities and data, restoring their authority.
• TALPA Inspection — TALPA-Inspection: Corrosion assessment of infrastructure with robotic systems (e.g., drones)