Top 45 Biotech Startup Investors in Portugal (September 2026)

Portfolio highlights

• Aptoide — Find, discover and download the best apps and games for Android in the official Aptoide app store
• Omniflow — Omniflow provides solutions powered by wind and solar for public spaces, Smart Lamppost, Smart Bench, Solar Smart Lighting, IoT Software, , Smart Pole, Smart City, Sustainability, CO2 reduction, decarbonization, Sustainable services
• Codeplace — The best place to develop your coding skills with a comprehensive, specially curated list of tutorials and books.

Portfolio highlights

• Growappy — Growappy is an EdTech that offers an all-in-one platform for early education that is leading a vision to unlock personalized education since nursery with the power of AI, while providing a revolutionary communication experience between schools and families and drastically simplifying bureaucracy for teachers and school owners.
• Noxus — At Spot, we're crafting the operating system for tomorrow's workforce, harnessing AI to streamline influencer marketing. Our platform empowers agencies, businesses, and content creators to collaborate effectively and reach audiences with ease.
• Infraspeak — Infraspeak is an Intelligent CMMS Software that brings outstanding flexibility, connectivity and intelligence to your operations.

Portfolio highlights

• Airflows — Airflows is a platform offering private AI solutions for back-office operations, enabling the creation of applications, workflows, and agent assistants from documents, rules, and approvals while maintaining full control, auditability, and integration with existing systems like ERP, ECM, and BPM.
• Neuraspace — Focus on fewer alerts with more time to manoeuver, with a scalable AI/ML solution from Neuraspace
• DOJO AI — The only tool you need to grow your Brand.

Portfolio highlights

• Pollen — Electric mobility for lightweight vehicles is about to get simpler, more affordable and more reliable.
• Wio Capital — Wio Capital is a wealthtech company that builds an AI-powered wealth management platform for financial advisors, offices, and bankers.
• Spacebackend — Lynapse by Spacebackend unifies interface modeling, version control, testing, and validation. Convert ICDs into traceable, deterministic implementations with human-in-the-loop review.

Portfolio highlights

• Vaxdyn — Preventing the next global health crisis Our mission is to prevent and alleviate the global health crisis caused by the pathogenic bacteria resistant to ant ...
• Laigo Bio — Laigo Bio uses E3 ligase internalization to precisely degrade membrane proteins linked to autoimmune and inflammatory disorders.
• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.

Portfolio highlights

• Hope Care Health — Hope Care is a digital health company that combines services, products, and cutting-edge technology platforms to enable the delivery of Social and Health Care without barriers.
• Reckon.ai — Whether you're building an unattended store or supplying the equipment behind it, Reckon's patented AI technology transforms existing infrastructure into smart, autonomous assets.
• Jscrambler — Jscrambler is the leading client-side security solution for JavaScript in-app protection and real-time webpage monitoring. Start your free trial today!

Portfolio highlights

• Almetra — We use computer vision and AI analytics to provide insights into manual assembly processes - our platform supports process engineers in driving productivity and quality of assembly processes
• Humanos — The Risk Network for AI https://t.co/RzfFeAgNCj
• RunSafe Security — Secure embedded systems with RunSafe Security's runtime cybersecurity protection, integrating build-time defenses without affecting performance.

Portfolio highlights

• pleez — Pleez offers Restaurant's an optimisation of their menu within Delivery Platforms, so that they can have a revenue increase up to 25%.
• Volup — Volup is a premium food delivery app that partners exclusively with top-tier chefs and restaurants.
• Mediaprobe — Not all impressions are created equal. Understand the emotional impact of your content. Learn about Mediaprobe - Next-gen media measurement.

Portfolio highlights

• Delox — Leader in advanced bio-discontamination solutions, Delox offers cutting-edge technology with vaporized hydrogen peroxide (VHP) for critical environments, laboratories, and healthcare. Validated safety and efficacy for a safer world.
• Adapttech — Adapttech is a biomedical company that uses innovative, smart and wearable technologies to deliver full adaptation and comfort to people with physical limitations.
• SolasCure — SolasCure aims to support healthcare professionals with wound care products that significantly improve the health and wellbeing of patients with chronic wounds.

Portfolio highlights

• AGADE — Esoscheletri Agade | Il primo esoscheletro intelligente per lavoratori progettato per ridurre il rischio di disturbi muscolari delle spalle nella movimentazione manuale dei carichi.
• BroadBit Batteries — BroadBit is a technology company developing revolutionary new batteries using novel sodium-based chemistries to power the future green economy.
• Aenitis Technologies — We develop innovative devices for cells therapy processing using Acoustic Radiation Forces.

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• Bighub — The All-in-One Platform for european marketplace growth. Integration, Catalog SEO, Pricing, Financing, Logistics, Helpdesk, and Resale.
• Flowbotic — development and manufacturing of AGVs and AMRs
• Bling Energy — Bling Energy is a startup that focuses on providing more efficient and sustainable energy solutions, mostly through solar panels.

Portfolio highlights

• Zen8 — Explore Connected Swim Training at zwim.com. Smart Swim Trainer + data + immersive game = real swim power. Train at home, get faster in the water. Join the waitlist now.
• Nutrium — Nutrium is the most up-to-date nutrition software for dietitians and nutritionists to manage their nutrition business with nutritional assessment, meal planning and progress tracking.
• PFx Biotech — PFx Biotech transforms food through bioinnovation by creating sustainable and nutritional alternative protein solutions.

Portfolio highlights

• DoJob.ai — Hybrid Intelligence Innovation Project
• OSCAR — OSCAR offers a variety of fixed-price home services, including maintenance, cleaning, laundry, and beauty services, all accessible through a user-friendly app. Customers can easily schedule appointments for these services, with options available for immediate bookings. Additionally, OSCAR provides repair services for household appliances likewashing machines and boilers, ensuring convenience for users. The platform streamlines the process of finding and scheduling necessary home services, catering to the needs of busy individuals and families. Through its comprehensive service offerings, OSCAR simplifies home management for its users.
• Fluxe Insurance Software — FLUXE develops AI software based to build digital tools for claim automation aligned with the challenges of the insurance industry!

Portfolio highlights

• 4iG — 4iG provides information technology solutions. The 4iG group of companies provides complex, high-quality services to its customers, which is due, among other things, to the continuous development of its product and service portfolio. They look for opportunities, are open to innovation, and are actively involved in technology research.
• TC2 — TC2 is Hungary's leading AWS partner. Cloud migration, AI solutions, managed services and 100+ certifications.
• Biometrid — Biometrid provides biometric identity verification and authentication solutions for secure onboarding and compliance.

Portfolio highlights

• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.
• BIMINI Biotech — BIMINI Biotech is a startup that develops innovative therapeutic strategies for oncology. It is developing therapeutic strategies that target the growth hormone receptor (GHR) and its interaction with insulin-like growth factor 1 (IGF-1) for oncology, metabolic diseases, and aging.The company was founded in 2019 and is based in Leiden, TheNetherlands.
• Mair Therapeutics — Mair Therapeutics main goal is finding and creating a small-molecule ion channel activator to treat Parkinson's disease, a preclinical drug discovery business.

Portfolio highlights

• Luca — Luca's learning platform provides learning programs for primary and secondary school students. The learning platform offers pre-recorded K12 videos, gamified content and AI powered personalized study paths, covering the entire official academic curriculum and national exams prep. Luca is a VC backed startup with HQ in Madrid & MexicoCity
• Neuraspace — Focus on fewer alerts with more time to manoeuver, with a scalable AI/ML solution from Neuraspace
• Spotlite — Spotlite combines satellite data with AI to predict infrastructure risks before they become problems.

Portfolio highlights

• BIZAY — Bizay enables the world’s largest catalogue of customizable products. Its technology platform operates across Europe, South and North America, and digitalizes the booming and huge industry of product customization by empowering brands, people and societies to self-express. It enables local manufacturers, brands, and wholesalers to offercustomization on any product in the world and reduces the cost of production by half through batching and supply-chain optimization technologies. Our platform/technology is aimed at three customer targets:(i) B2B2C provides a platform for businesses to design and sell customized products from Bizay’s existing product catalogue, with the four main customer segments: Resellers, Content Creators (Independent artists, influencers or event or managers that want to sell customized merchandise with their branding, designs or artwork), e-Commerce entrepreneurs (Small entrepreneurs that aim to expand their catalogue and upgrade their business by adding customized products to their online stores), as well as big household brands & enterprises (well-established business in need of a partner that is capable of handling large volume of customized products orders or to expand their existing offer)(ii) B2B, which is focused on SMBs, provides an extensive product catalogue for customized products to be used in several industries (ex: uniforms for restaurants and bags for retail shops) (iii) Customization-as-a-Service (CaaS), where clients (typically major brands) capitalize on Bizay’s technology, expertise, customization options, techniques and offline suppliers to customize their own products
• Nutrium — Nutrium is the most up-to-date nutrition software for dietitians and nutritionists to manage their nutrition business with nutritional assessment, meal planning and progress tracking.
• Neuraspace — Focus on fewer alerts with more time to manoeuver, with a scalable AI/ML solution from Neuraspace

Portfolio highlights

• Silentvector — Biotechnology applied to agriculture. Research, development, innovation, and production of bioprotectants, biofertilizers, biostimulants, and nutrients of biological origin.

Portfolio highlights

• Promptly — Health Analytics Patient Report Outcomes, Health Care, Value based health
• Healthplus.ai — Healthplus.ai enables surgical care professionals to be more proactive towardcs patients, care and outcome; predicting infections before they are normally diagnosed.
• NVision Quantum Technologies — NVision Imaging Technologies is leveraging advances in quantum physics to enable the first routine, convenient and affordable use of Magnetic Resonance Imaging (MRI) for assessing early patient response to cancer treatment at the metabolic level.

Portfolio highlights

• Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.

Portfolio highlights

• Claryx — The hospital immune system. Claryx detects each infection, traces how it's spreading, recommends a response, and confirms that it's gone.
• SkinBit — SkinBit is a healthtech company that develops AI-powered skin cancer detection, digital mapping, and health monitoring solutions.
• Elita — Store your dog's stem cells with Elita. One-time opportunity to protect their future health and avoid costly surgeries later in life.

Portfolio highlights

• OmniumAI — OmniumAI are developing CibusAI to revolutionise traditional food reformulation.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• DigiLens — DigiLens is an innovator in holographic waveguide display technology for extended reality (XR).DigiLens has developed a patented optical platform and photopolymer technology that delivers best-in-class solutions using a unique, low-cost contact-copy manufacturing process. DigiLens enables OEM partners to design and build XR-enabled devices for theglobal automobile, enterprise, consumer, avionics, and military industries.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.
• Applecrumby & Fish — Applecrumby & Fish is an online and offline baby store that offers various brands of baby products available both locally and internationally. The baby products are classified under the categories: bath and skincare, food and health, feeding, baby gear, diapers and potty, playroom, maternity, and school.Putto, Brush Baby, Tommee Tippee,Hot-Kid, Nordic Naturals, Annie’s Organic, Zoli, Munchkin, Avent, Clevamama, Attitude, Potette Plus, The First Years, Renova, Peaceable Kingdom, Mega Bloks, Emma-Jane, MooGoo, Stephen Joseph, and Thinkbaby are some of the brands available in Applecrumby & Fish’s stores.Applecrumby & Fish was founded in 2011 and is based in Selangor, Malaysia.

Portfolio highlights

• Rofim — Rofim provides a multidisciplinary platform that combines practitioners' knowledge, technology for analyses, and medical imaging to provide a diagnosis. In order to share knowledge and provide the most accurate and timely diagnosis possible, Rofim concentrates on all the functionalities created for fluid medical use. The company is dedicatedto making the daily lives of physicians, patients, and medical institutions easier, more moral, and more seamless.
• Hoopers — Global basketball community platform connecting players, fans and enthusiasts through products, contents, experiences and NFTs.
• Hope Care Health — Hope Care is a digital health company that combines services, products, and cutting-edge technology platforms to enable the delivery of Social and Health Care without barriers.

Portfolio highlights

• Biobase — Biobase is the agentic system for clinical data, closing the gap between clinical data and better healthcare.
• Ladder Health — Ladder Health offers virtual pediatric therapy and support for early childhood developmental delays, including speech and physical therapy.
• Woodway Assurance — Woodway Assurance provides EviData, an AI-driven software for automated privacy assurance on de-identified and synthetic datasets.

Portfolio highlights

• Lyzer — The groceries marketplace where you can find everthing you need. Buy online groceries as fast as in 4 hours with personalized picking.
• Musiversal — Record your music in real time with world-class session musicians, vocalists, producers and audio engineers
• Primetag — AI-native influencer & creator marketing platform for brands & agencies. Find the best creators, analyse the market and competitors, and measure campaign performance.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Tucuvi — Tucuvi is a health technology company unlocking efficient and high-quality healthcare at scale with a CE-marked platform for Phone Consultation Automation. We develop safe and clinically validated Conversational AI for any care pathway, enabling clinical teams to augment their capacities, improve processes’ efficiency and efficacy, and achievebetter patient outcomes and satisfaction through continuous and personalized care.
• Balance — Balance is a private digital health company based in Spain that operates in the clinics and outpatient healthcare services sector. company's core mission is to provide an integrated, medical, and sustainable approach to treating obesity and overweight conditions. Moving away from traditional restrictive diets, the company leverages asubscription-based telehealth model combined with clinical pharmacology.
• Punto Health — AI-powered digital platform for management of Alzheimer's and other dementias.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Flow Eighteen38 — FairJourney Bio connects discovery, engineering, characterisation and development in one accountable workflow for therapeutic antibody programmes.

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• Biosurfit — At biosurfit they are working to shape the future of in-vitro diagnostic testing. They want health providers to have all the necessary information to make the best possible diagnostic and treatment decision when they are with their patients

Portfolio highlights

• Porelio — Porelio is an environmental technology that provides purification technologies for water and industrial chemicals.
• ATMOS Space Cargo — ATMOS Space Cargo develops and manufactures space capsules to return cargo from space, microgravity experiments, Commercial products to entire rocket stages.
• InSpacePropulsion Technologies — Cost-effective, robust, and quickly available propulsion solutions, based on 10+ years of R&D and 40 years of combined experience in space propulsion.

Portfolio highlights

• Tecmafoods - Taking us Further — taking us further

Portfolio highlights

• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• Findster — Findster is a pet tech company that provides peace of mind to pet owners by helping them keep track of their pet's location and well-being 24/7. In 2016, Findster introduced the first GPS tracker to allow true real-time monitoring and to not require monthly fees - Findster Duo - via a $250k Kickstarter campaign. The company has sincebecome one of the fastest growing pet tech companies in the world, with the Duo currently being the #1 Best Seller in its category on Amazon.com and used in over 80 countries on a daily basis.At the core of Findster is Maze®, a proprietary technology platform that allows IoT systems to communicate in real-time, off-grid, in a long-range without being dependent on the cellular infrastructure from Telcos.
• CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!

Portfolio highlights

• Abtrace — Abtrace is an automated, self-learning care system where we can provide personalised care, delivered at population scale - where predictive, preventative and proactive approaches keep people healthy and out of hospital.
• sheerME — SheerME is Revolutionising the way people find, book, and pay for their Wellness and Beauty services powered by a benefit-based walletOur approach is based on Discovery, Transaction & Reward to create more online visibility, reach, conversion into new business, loyalty, and frequency through our wallet and cashback ecosystem, to all ourpartners in the beauty and wellness sectors.This made us a fresh and different option in this sector where there are mainly SaaS players, and we bring marketplace with no monthly fee, only a commission for business sent through our owned and partner channels.
• ChemiTek — Certified & sustainable solutions for industrial maintenance. We have the solutions you need!

Portfolio highlights

• Insilico Medicine — Artificial Intelligence for Drug Discovery and Aging Research
• Star Therapeutics — Star Therapeutics mission is to develop therapies for as many diseases as possible for millions of patients.
• Affimed — At Affimed, they are committed to improving outcomes for patients with cancer. Their scientific team has been devoted to unlocking the power of the innate immune system for nearly two decades to provide a unqiue approach to fighting cancer. With their unparalleled expertise in innate immunity and innate cell engager-based medicines, they aim toovercome the limitations and challenges faced by current immuno-oncology (I-O) therapies.

Portfolio highlights

• NobodyWho — NobodyWho is an inference engine that lets you run LLMs locally on any device
• FION Energy — FION Energy GmbH is a Berlin-based company at the forefront of the clean energy transition, specializing in advanced energy storage and management solutions for industrial businesses. Their technology helps companies optimize energy use, reduce costs, enhance grid stability, and accelerate decarbonization by providing economically viable storagesystems tailored to each customer's needs. FION supports grid operators by enabling efficient orchestration of energy consumption and generation, contributing to a more stable and sustainable energy future. They offer personalized consulting, rapid installation, and continuous optimization of energy storage performance to maximize cost savings and flexibility.
• Bubble Robotics — Building the ocean's autonomous workforce, powering infrastructure, ecosystems & resilience.

Portfolio highlights

• Irisbond — Irisbond creates a new way for humans to communicate through precision eye-tracking technology. Irisbond’s advanced software algorithms interpret your eye gaze in order to provide natural, intuitive and hands-free access to information and control over a screen. Developed for use in mobile devices, automotive, smart homes, robotics, scientific,healthcare and manufacturing, eye tracking technology lets you learn, play, work and communicate with your eyes. A pioneer in the assistive technology market, Irisbond’s eye tracking solutions are based on years of R&D in cooperation with Vicomtech, a leader in the field of artificial vision. For more information about the power of the eyes, go to www.irisbond.com/en
• tuTECHÔ — tuTECHÔ is an innovative social enterprise born with the purpose of contributing to the eradication of homelessness in Spain.
• Suara Cooperativa — Suara Cooperativa is a non-profit organization that provides education to children and youth and elder care services.

Portfolio highlights

• CUZIN — CUZIN is your global shopping family. A community marketplace enabling members to purchase any product worldwide by leveraging other members’ buying access or advantages.Members post requests for any product they want from anywhere in the world. Online or offline, specialist boutiques/clearance outlets and sales. This request is pushed to'cuzins' best placed (geographically or commercially) to purchase the item on their behalf. Cuzins earn a tip for helping out!In addition to accepting a shopping request, any cuzin can instantly monetise being in the right place at the right time posting a purchase opportunity, which is pushed to interested members worldwide. Shopping, shipping, social. Sorted. CUZIN provides the social and logistics platform to facilitate the matching, communication, payment and shipping of the items we love worldwide.
• Vaulta — Vaulta is a battery casing technology company based in Brisbane, Australia. Using advanced composite materials and smart, streamlined design, Vaulta has developed a lighter and smaller battery case with fewer parts, creating scalable efficiencies and opportunities for manufacturers. Vaulta founder and director Dominic Spooner has over 12 yearsexperience as a design engineer, and has worked in a range of industries, including renewables and batteries, defence and aerospace, consumer products, commercial products and startups. While working in battery design, Dominic saw firsthand that opportunities for growth were being overlooked in favour of continuing with the status quo – and that’s when the idea for Vaulta was born.Vaulta’s world-first no-weld design means modules can be easily assembled and disassembled, cells reused and recycled, and new cells added as battery technology continues to evolve.From stationary storage and electric vehicles to defence, aerospace and beyond, Vaulta’s battery case technology works wherever batteries do.
• Andromeda Robotics — At Andromeda, our personalised robot companions are helping Australian aged care teams bring joy and connection to residents to improve wellbeing.

Portfolio highlights

• Meniga — Meniga helps banks use data to drive Digital Engagement, build Customer Loyalty & increase Revenue.
• Capwatt — Capwatt is an integrated energy solution offering sustainable energy, energy efficiency, and asset management services.

Portfolio highlights

• Mediaprobe — Not all impressions are created equal. Understand the emotional impact of your content. Learn about Mediaprobe - Next-gen media measurement.
• Habit — Habit's mission is to bring context and meaningfulness to the way insurance is sold. We connect brands with insurers to enable the best way to distribute insurance - on digital.