Top 40 Biotech Startup Investors in Portugal (August 2026)

Portfolio highlights

• AddVolt — AddVolt is a technology based company that tackles markets where there is a high potential for diesel costs reduction through the generation of solar and kinetic energy, while other secondary savings are generated (e.g. maintenance).
• Unlockit — Unlockit will offer to public and governmental bodies the guarantee that everything within a real estate transaction is recorded, meaning better industry regulation, more taxes and public fees collected, and less overall fraud and money laundering activities.
• Logical Safety — IoT safety for a safer, more productive workforce

Portfolio highlights

• Veniam — Transfer 10x more data for your video telematics, fleet operations, industrial IoT or connected vehicles.
• Growappy — Growappy is an EdTech that offers an all-in-one platform for early education that is leading a vision to unlock personalized education since nursery with the power of AI, while providing a revolutionary communication experience between schools and families and drastically simplifying bureaucracy for teachers and school owners.
• Infraspeak — Infraspeak is an Intelligent CMMS Software that brings outstanding flexibility, connectivity and intelligence to your operations.

Portfolio highlights

• Airflows — Airflows is a platform offering private AI solutions for back-office operations, enabling the creation of applications, workflows, and agent assistants from documents, rules, and approvals while maintaining full control, auditability, and integration with existing systems like ERP, ECM, and BPM.
• Neuraspace — Focus on fewer alerts with more time to manoeuver, with a scalable AI/ML solution from Neuraspace
• DOJO AI — The only tool you need to grow your Brand.

Portfolio highlights

• Pollen — Electric mobility for lightweight vehicles is about to get simpler, more affordable and more reliable.
• Wio Capital — Wio Capital is a wealthtech company that builds an AI-powered wealth management platform for financial advisors, offices, and bankers.
• Spacebackend — Lynapse by Spacebackend unifies interface modeling, version control, testing, and validation. Convert ICDs into traceable, deterministic implementations with human-in-the-loop review.

Portfolio highlights

• Reckon.ai — Whether you're building an unattended store or supplying the equipment behind it, Reckon's patented AI technology transforms existing infrastructure into smart, autonomous assets.
• Jscrambler — Jscrambler is the leading client-side security solution for JavaScript in-app protection and real-time webpage monitoring. Start your free trial today!
• CorPower Ocean — CorPower Ocean AB was founded in 2009 to develop high efficiency Wave Energy Converters (WECs).CorPower's Wave Energy Converters deliver five times higher annual energy output per ton of device compared to previously known wave power solutions. The step-change improvement in performance and efficiency allows a Cost-of-Energy that cancompete with offshore wind. The products are currently in pilot with Iberdrola. CorPower has assembled a team with extensive experience in energy generation, design and manufacturing of production equipment, system engineering as well as the market expertise to allow us to continue transforming the technology of tomorrow into renewable energy applications of today.

Portfolio highlights

• Laigo Bio — Laigo Bio uses E3 ligase internalization to precisely degrade membrane proteins linked to autoimmune and inflammatory disorders.
• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.

Portfolio highlights

• pleez — Pleez offers Restaurant's an optimisation of their menu within Delivery Platforms, so that they can have a revenue increase up to 25%.
• Volup — Volup is a premium food delivery app that partners exclusively with top-tier chefs and restaurants.
• MindProber — Not all impressions are created equal. Understand the emotional impact of your content. Learn about Mediaprobe - Next-gen media measurement.

Portfolio highlights

• Delox — Leader in advanced bio-discontamination solutions, Delox offers cutting-edge technology with vaporized hydrogen peroxide (VHP) for critical environments, laboratories, and healthcare. Validated safety and efficacy for a safer world.
• CellmAbs — Pharmaceutical Company, Biotechnology
• SolasCure — SolasCure aims to support healthcare professionals with wound care products that significantly improve the health and wellbeing of patients with chronic wounds.

Portfolio highlights

• MixRift — MIXRIFT - game developers specialized in Mixed Reality
• unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
• Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

Portfolio highlights

• Bighub — The All-in-One Platform for european marketplace growth. Integration, Catalog SEO, Pricing, Financing, Logistics, Helpdesk, and Resale.
• Bling Energy — Bling Energy is a startup that focuses on providing more efficient and sustainable energy solutions, mostly through solar panels.
• TWEVO Technologies — Solutions for i4.0 | Detection + Supervision + Control State-of-the-art AI video processing and encoding, ultra-fast Edge-AI electronics implementations complement and strengthen real-time factory worker responses, optimised video processing and transmission to provide full video information on the factory floor.

Portfolio highlights

• Zen8 — Explore Connected Swim Training at zwim.com. Smart Swim Trainer + data + immersive game = real swim power. Train at home, get faster in the water. Join the waitlist now.
• Nutrium — Nutrium is the most up-to-date nutrition software for dietitians and nutritionists to manage their nutrition business with nutritional assessment, meal planning and progress tracking.
• PFx Biotech — PFx Biotech transforms food through bioinnovation by creating sustainable and nutritional alternative protein solutions.

Portfolio highlights

• DoJob.ai — Hybrid Intelligence Innovation Project
• OSCAR — OSCAR offers a variety of fixed-price home services, including maintenance, cleaning, laundry, and beauty services, all accessible through a user-friendly app. Customers can easily schedule appointments for these services, with options available for immediate bookings. Additionally, OSCAR provides repair services for household appliances likewashing machines and boilers, ensuring convenience for users. The platform streamlines the process of finding and scheduling necessary home services, catering to the needs of busy individuals and families. Through its comprehensive service offerings, OSCAR simplifies home management for its users.
• Fluxe Insurance Software — FLUXE develops AI software based to build digital tools for claim automation aligned with the challenges of the insurance industry!

Portfolio highlights

• 4iG — 4iG provides information technology solutions. The 4iG group of companies provides complex, high-quality services to its customers, which is due, among other things, to the continuous development of its product and service portfolio. They look for opportunities, are open to innovation, and are actively involved in technology research.
• TC2 — TC2 is Hungary's leading AWS partner. Cloud migration, AI solutions, managed services and 100+ certifications.
• Polygon — Polygon provides biometrics, authentication, voice biometrics, mobile biometrics, facial recognition, liveness detection, identification, document validation, and identity verification services.

Portfolio highlights

• Almetra — We use computer vision and AI analytics to provide insights into manual assembly processes - our platform supports process engineers in driving productivity and quality of assembly processes
• Humanos — The Human Authorization Layer for AI https://t.co/RzfFeAgNCj
• RunSafe Security — Secure embedded systems with RunSafe Security's runtime cybersecurity protection, integrating build-time defenses without affecting performance.

Portfolio highlights

• Flow Eighteen38 — FairJourney Bio connects discovery, engineering, characterisation and development in one accountable workflow for therapeutic antibody programmes.

Portfolio highlights

• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Tucuvi — Tucuvi is a health technology company unlocking efficient and high-quality healthcare at scale with a CE-marked platform for Phone Consultation Automation. We develop safe and clinically validated Conversational AI for any care pathway, enabling clinical teams to augment their capacities, improve processes’ efficiency and efficacy, and achievebetter patient outcomes and satisfaction through continuous and personalized care.
• Balance — Balance is a private digital health company based in Spain that operates in the clinics and outpatient healthcare services sector. company's core mission is to provide an integrated, medical, and sustainable approach to treating obesity and overweight conditions. Moving away from traditional restrictive diets, the company leverages asubscription-based telehealth model combined with clinical pharmacology.
• Punto Health — AI-powered digital platform for management of Alzheimer's and other dementias.

Portfolio highlights

• Rofim — Rofim provides a multidisciplinary platform that combines practitioners' knowledge, technology for analyses, and medical imaging to provide a diagnosis. In order to share knowledge and provide the most accurate and timely diagnosis possible, Rofim concentrates on all the functionalities created for fluid medical use. The company is dedicatedto making the daily lives of physicians, patients, and medical institutions easier, more moral, and more seamless.
• Hoopers — Global basketball community platform connecting players, fans and enthusiasts through products, contents, experiences and NFTs.
• PluggableAI — FAN OF THE MATCH transforms fan passion in live events, sports, and media into AI-driven insights that boost engagement and create new revenue opportunities

Portfolio highlights

• Biobase — Biobase is the agentic system for clinical data, closing the gap between clinical data and outcomes.
• Ladder Health — Ladder Health offers virtual pediatric therapy and support for early childhood developmental delays, including speech and physical therapy.
• Woodway Assurance — Woodway Assurance provides EviData, an AI-driven software for automated privacy assurance on de-identified and synthetic datasets.

Portfolio highlights

• Lyzer — The groceries marketplace where you can find everthing you need. Buy online groceries as fast as in 4 hours with personalized picking.
• Musiversal — Record your music in real time with world-class session musicians, vocalists, producers and audio engineers
• Primetag — AI-native influencer & creator marketing platform for brands & agencies. Find the best creators, analyse the market and competitors, and measure campaign performance.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Abtrace — Abtrace is an automated, self-learning care system where we can provide personalised care, delivered at population scale - where predictive, preventative and proactive approaches keep people healthy and out of hospital.
• sheerME — SheerME is Revolutionising the way people find, book, and pay for their Wellness and Beauty services powered by a benefit-based walletOur approach is based on Discovery, Transaction & Reward to create more online visibility, reach, conversion into new business, loyalty, and frequency through our wallet and cashback ecosystem, to all ourpartners in the beauty and wellness sectors.This made us a fresh and different option in this sector where there are mainly SaaS players, and we bring marketplace with no monthly fee, only a commission for business sent through our owned and partner channels.
• ChemiTek — Certified & sustainable solutions for industrial maintenance. We have the solutions you need!

Portfolio highlights

• CardiAQ Valve Technologies — CardiAQ Valve Technologies (CVT), a privately held company, is developing innovative approaches to heart valve replacement and is initially focused on transcatheter mitral valve implantation (TMVI).
• Sonendo — Sonendo developing innovative technologies to transform dentistry by Saving Teeth Through Sound Science®. The GentleWave® System shows significant improvements in clinical efficacy and practice efficiency when compared to standard root canal treatment.1,2, 3 Sonendo is the parent company of TDO® Software, the developer of the most widely usedendodontic practice management software in the world, designed to simplify practice workflow. TDO software seamlessly integrates practice management, imaging, social media, referral reporting, CBCT imaging, and offers built-in communication with the GentleWave System.
• Acceleron Pharma — At Merck, we're following the science to tackle some of the world's greatest health threats. Get a glimpse of how we work to improve lives.

Portfolio highlights

• NobodyWho — NobodyWho is an inference engine that lets you run LLMs locally on any device
• FION Energy — FION Energy GmbH is a Berlin-based company at the forefront of the clean energy transition, specializing in advanced energy storage and management solutions for industrial businesses. Their technology helps companies optimize energy use, reduce costs, enhance grid stability, and accelerate decarbonization by providing economically viable storagesystems tailored to each customer's needs. FION supports grid operators by enabling efficient orchestration of energy consumption and generation, contributing to a more stable and sustainable energy future. They offer personalized consulting, rapid installation, and continuous optimization of energy storage performance to maximize cost savings and flexibility.
• Bubble Robotics — Building the ocean's autonomous workforce, powering infrastructure, ecosystems & resilience.

Portfolio highlights

• Irisbond — Irisbond creates a new way for humans to communicate through precision eye-tracking technology. Irisbond’s advanced software algorithms interpret your eye gaze in order to provide natural, intuitive and hands-free access to information and control over a screen. Developed for use in mobile devices, automotive, smart homes, robotics, scientific,healthcare and manufacturing, eye tracking technology lets you learn, play, work and communicate with your eyes. A pioneer in the assistive technology market, Irisbond’s eye tracking solutions are based on years of R&D in cooperation with Vicomtech, a leader in the field of artificial vision. For more information about the power of the eyes, go to www.irisbond.com/en
• tuTECHÔ — tuTECHÔ is an innovative social enterprise born with the purpose of contributing to the eradication of homelessness in Spain.
• Suara Cooperativa — Suara Cooperativa is a non-profit organization that provides education to children and youth and elder care services.

Portfolio highlights

• LivedCX® — LIVEDCX: Advanced AI technology for contact centre leaders who must simplify complexity to create growth.
• Andromeda Robotics — At Andromeda, our personalised robot companions are helping Australian aged care teams bring joy and connection to residents to improve wellbeing.
• Infiction labs — SPARC 1.2 is a solar panel robotic cleaning system designed and developed by Infiction Labs Pvt Ltd for commercial solar plants.

Portfolio highlights

• CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!

Portfolio highlights

• Meniga — Meniga helps banks use data to drive Digital Engagement, build Customer Loyalty & increase Revenue.
• Capwatt — Capwatt is an integrated energy solution offering sustainable energy, energy efficiency, and asset management services.

Portfolio highlights

• MindProber — Not all impressions are created equal. Understand the emotional impact of your content. Learn about Mediaprobe - Next-gen media measurement.
• Habit — Habit's mission is to bring context and meaningfulness to the way insurance is sold. We connect brands with insurers to enable the best way to distribute insurance - on digital.

Portfolio highlights

• Jiseki Health — Jiseki is built on the belief that families and communities need and deserve a safety net, and to have peace of mind when things go wrong. We provide access and delivery of key advice, help, products and services through highly scalable SMS technology, powered by a combination of professionals and AI, and sold as a portable life benefit package..Text #help to 543210, to discover Jiseki services.
• Biome Analytics — Biome is an analytic applications that help cardiovascular teams do their best work. It helps forward thinking hospitals profitably transition and thrive in the new world of healthcare. During COVID-19, Biome has focused on assessing hospital capacity.
• NEXT Life Sciences — NEXT Life Sciences is developing the revolutionary Plan A™ procedure to bring the only scientifically proven technology in the category - Vasalgel® - to market.

Portfolio highlights

• Mondego Bio — Headquartered in Portugal’s main biotech park, Biocant, Mondego Bio is developing best-in-class protein tyrosine phosphatase non-receptor type 2 (PTPN2) inhibitors, providing a potential immuno-oncological therapy with an improved safety and tolerability profile.
• BIMINI Biotech — BIMINI Biotech is a startup that develops innovative therapeutic strategies for oncology. It is developing therapeutic strategies that target the growth hormone receptor (GHR) and its interaction with insulin-like growth factor 1 (IGF-1) for oncology, metabolic diseases, and aging.The company was founded in 2019 and is based in Leiden, TheNetherlands.
• Chromis Therapeutics — Chromis Therapeutics, Inc. (Chromis) is a San Diego-based biopharmaceutical company, focused on the development of curative treatments for chronic HBV infection, based on its advanced proprietary drug design and discovery platform. The company is seeking investment to advance its novel cccDNA inhibitor (CHR101), viral entry and viral capsidassembly inhibitor lead candidates for the treatment of chronic HBV. CHR101 has a potential to eradicate HBV and to efficiently cure chronically infected HBV patients, as compared to drugs currently on the market. CHR101's activity is supported by a robust discovery preclinical data package.

Portfolio highlights

• Luca — Luca's learning platform provides learning programs for primary and secondary school students. The learning platform offers pre-recorded K12 videos, gamified content and AI powered personalized study paths, covering the entire official academic curriculum and national exams prep. Luca is a VC backed startup with HQ in Madrid & MexicoCity
• Neuraspace — Focus on fewer alerts with more time to manoeuver, with a scalable AI/ML solution from Neuraspace
• Spotlite — Spotlite combines satellite data with AI to predict infrastructure risks before they become problems.

Portfolio highlights

• BIZAY — Bizay enables the world’s largest catalogue of customizable products. Its technology platform operates across Europe, South and North America, and digitalizes the booming and huge industry of product customization by empowering brands, people and societies to self-express. It enables local manufacturers, brands, and wholesalers to offercustomization on any product in the world and reduces the cost of production by half through batching and supply-chain optimization technologies. Our platform/technology is aimed at three customer targets:(i) B2B2C provides a platform for businesses to design and sell customized products from Bizay’s existing product catalogue, with the four main customer segments: Resellers, Content Creators (Independent artists, influencers or event or managers that want to sell customized merchandise with their branding, designs or artwork), e-Commerce entrepreneurs (Small entrepreneurs that aim to expand their catalogue and upgrade their business by adding customized products to their online stores), as well as big household brands & enterprises (well-established business in need of a partner that is capable of handling large volume of customized products orders or to expand their existing offer)(ii) B2B, which is focused on SMBs, provides an extensive product catalogue for customized products to be used in several industries (ex: uniforms for restaurants and bags for retail shops) (iii) Customization-as-a-Service (CaaS), where clients (typically major brands) capitalize on Bizay’s technology, expertise, customization options, techniques and offline suppliers to customize their own products
• Nutrium — Nutrium is the most up-to-date nutrition software for dietitians and nutritionists to manage their nutrition business with nutritional assessment, meal planning and progress tracking.
• Neuraspace — Focus on fewer alerts with more time to manoeuver, with a scalable AI/ML solution from Neuraspace

Portfolio highlights

• DigiLens — DigiLens is an innovator in holographic waveguide display technology for extended reality (XR).DigiLens has developed a patented optical platform and photopolymer technology that delivers best-in-class solutions using a unique, low-cost contact-copy manufacturing process. DigiLens enables OEM partners to design and build XR-enabled devices for theglobal automobile, enterprise, consumer, avionics, and military industries.
• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.
• Applecrumby & Fish — Applecrumby & Fish is an online and offline baby store that offers various brands of baby products available both locally and internationally. The baby products are classified under the categories: bath and skincare, food and health, feeding, baby gear, diapers and potty, playroom, maternity, and school.Putto, Brush Baby, Tommee Tippee,Hot-Kid, Nordic Naturals, Annie’s Organic, Zoli, Munchkin, Avent, Clevamama, Attitude, Potette Plus, The First Years, Renova, Peaceable Kingdom, Mega Bloks, Emma-Jane, MooGoo, Stephen Joseph, and Thinkbaby are some of the brands available in Applecrumby & Fish’s stores.Applecrumby & Fish was founded in 2011 and is based in Selangor, Malaysia.

Portfolio highlights

• Silentvector — Biotechnology applied to agriculture. Research, development, innovation, and production of bioprotectants, biofertilizers, biostimulants, and nutrients of biological origin.

Portfolio highlights

• Promptly — Health Analytics Patient Report Outcomes, Health Care, Value based health
• Healthplus.ai — Healthplus.ai enables surgical care professionals to be more proactive towardcs patients, care and outcome; predicting infections before they are normally diagnosed.
• NVision Quantum Technologies — NVision Imaging Technologies is leveraging advances in quantum physics to enable the first routine, convenient and affordable use of Magnetic Resonance Imaging (MRI) for assessing early patient response to cancer treatment at the metabolic level.

Portfolio highlights

• BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Portfolio highlights

• Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Portfolio highlights

• Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.