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Top 25 Biotech Startup Investors in Portugal in January 2026

Last updated: Jan 2026 A list of 25 angel investors and VC (Venture Capital) funds that invest in Biotech startups based in Portugal. We rank investors based on the number of investments they made in Biotech companies from Portugal. We update this investor list every month.

Top 25 Biotech Startup Investors in Portugal in January 2026

Investor	Biotech Portugal investments
Portugal Ventures	12
Caixa Capital	6
Armilar Venture Partners	3
Bynd Venture Capital	3
SOSV	2
Critical Ventures	2
Fairjourney Biologics	1
InterCapital Group	1
Scott MacMillan	1
ChangePartners	1
WISENEXT	1
Beta Capital	1
Ganexa Capital	1
Boost VC	1
Pedro Lourenço	1
Nina Capital	1
StartUp Health	1
Social Impact Fund	1
Pathena	1
Teak Capital	1
Shilling VC	1
Jeremy Hendon	1
Michael Chang	1
Bionova Capital	1
InterCapital	1

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Investor list

Verticals:Enterprise, SaaS, Security, Networks, AI, VR/AR, Marketplace, Blockchain, Internet of Things, New materials, Electronics, Robotics, Cleantech, Agrotech, Seatech, Therapeutics, Digital Health, Diagnostics, Innovative Accommodation, Tourist Entertainment Companies, Tour Operators, Wine, Nautical and Equestrian Tourism, Theme ParksMobile, Robotics Founded in 2012, Portugal Ventures is a venture capital firm based in Porto, Portugal. The firm is a part of the Banco Português de Fomento group. The firm seeks to invest in pre-seed, seed and series A stages

Investment focus

Software, Information Technology, Health Care
Seed, Funding Round, Pre-Seed
Portugal, United States, France

Portfolio highlights

AddVolt — AddVolt is a technology based company that tackles markets where there is a high potential for diesel costs reduction through the generation of solar and kinetic energy, while other secondary savings are generated (e.g. maintenance).
Hephaesnus — Hephaesnus is an industrial technology startup dedicated to the development of products and technologies for forest firefighting.
Floating Particle — Floating Particle is a technology and innovation company that drives an innovative solution for waste management and clean energy. Floating Particle specializes in IoT, Big Data and Machine Learning to provide cutting-edge technology to the customers.

Caixa Capital is the Private Equity and Venture Capital arm of banking Group Caixa Geral de Depósitos and has a track record spanning over two decades of activity, since the industry was created in Portugal. It is a leading investor in terms of funds under management, portfolio size and diversity.Caixa Capital´s mission is to invest in fundsand companies, led by highly qualified management teams, with high growth and valuation potential, that enable our funds to achieve an attractive risk adjusted return and for society at large to benefit sustainably from our activity.Currently with more than 700 million Euros under management and a portfolio of over 80 investments, Caixa Capital is a reference in this area with special links to the respective European sector associations.

Investment focus

Software, Information Technology, SaaS
Seed, Series A, Funding Round
Portugal, United States, Spain

Portfolio highlights

HiJiffy — Increase direct bookings and upselling with HiJiffy's AI-powered communication solutions for hospitality.
Noxus — At Spot, we're crafting the operating system for tomorrow's workforce, harnessing AI to streamline influencer marketing. Our platform empowers agencies, businesses, and content creators to collaborate effectively and reach audiences with ease.
Infraspeak — Infraspeak is an Intelligent CMMS Software that brings outstanding flexibility, connectivity and intelligence to your operations.

Armilar Venture Partners is Portugal's leading venture capitalist. An independent VC with a 20-year-old history, a high-performance track record and an international footprint, Armilar is a deep-tech investor in ICT, HealthTech and CleanTech.

Investment focus

Software, Information Technology, Manufacturing
Series A, Seed, Funding Round
Portugal, United States, United Kingdom

Portfolio highlights

Cintoo — Cintoo is essential for BIM to bridge the gap between your physical and virtual worlds.
Automaise — Radically improve your customer care operations by focusing where the volume is and helping your agents do a better job.
Sword Health — Sword delivers AI Care with clinical oversight to prevent pain, support recovery, and promote whole-body health. Trusted by employers and health plans.

Bynd is a leading Iberian Venture Capital firm

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Series A
Portugal, Spain, United States

Portfolio highlights

Dealcar — DEALCAR is a company that digitalizes the used car market through a SaaS platform, enabling fully digital transactions. This platform creates a network effect benefiting dealers, partners, and customers. • Dealers: Increase revenue by selling extra products and boost sales by reducing turnover time. • Partners: Distribute products at the pointof sale without marketing expenses, lowering operational costs. • Consumers: Purchase a used car easily in just three steps, enjoying a smooth, trusted process similar to renting but with the benefits of owning a car.
nuuEnergy — nuuEnergy is a tech-enabled solution aiming to revolutionize the heat pump installation industry. By leveraging technology and industry expertise, we streamline the purchasing and installation process. Our unique approach, refinanced through innovative strategies, promotes a self-reliant and carbon-neutral lifestyle for all our customers.
Relive — Relive is empowering the next generation of real estate entrepreneurs, with a mobile app that allows them to work for themselves, from anywhere, while saving time and earning commissions faster.

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

We invest in game-changing companies with the power to transform the way the world uses technology.

Investment focus

Medical, Computer, Genetics
Seed, Series A
Portugal, United States

Portfolio highlights

hOS — hOS is an early-stage AI technology company.
CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!
RunSafe Security — Secure embedded systems with RunSafe Security's runtime cybersecurity protection, integrating build-time defenses without affecting performance.

FairJourney Biologics is your end-to-end antibody discovery and biologics partner, offering world-class mammalian display, cell-line development and protein production services to accelerate therapeutic pipelines.

Investment focus

Biotechnology
Corporate Round
Portugal

Portfolio highlights

Flow Eighteen38 — FairJourney Biologics is your end-to-end antibody discovery and biologics partner, offering world-class mammalian display, cell-line development and protein production services to accelerate therapeutic pipelines.

InterCapital Group provides management consulting and business advisory services to a wide range of companies, executives management teams and startups. We have the capacity to assist our clients in a variety of ways including business strategy, marketing plans, product development, angel investment or venture capital raises, social mediaconsulting, human resources, operational improvement, developing or strengthening a executive team or advisory board .The InterCapital Group typically works with clients and companies with less than $10 million on annual revenue. Current and past clients consist of companies from many sectors including financial services, consumer web, high-tech, software, mobile, media, communications, retail, hospitality, consumer products, consumer services, social media, nonprofits, insurance and wealth management.

Investment focus

Biofuel, Biotechnology
Seed
Portugal

Portfolio highlights

BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Scott MacMillan

Investment focus

Apps, Fitness, Big Data
Pre-Seed
Portugal

Portfolio highlights

Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

ChangePartners is an independent company dedicated to mid-size transactions in the Iberian market. They develop high value added solutions specific to each particular situation , offering a fair and unbiased opinion. Their independence guarantees no conflicts of interest. Their small size and focus ensures full dedication to each transaction.

Investment focus

Medical, Therapeutics, Biotechnology
Seed
Portugal

Portfolio highlights

Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.

WiseNext is a venture and smart capital investment company. We focus on helping young entrepreneurs with innovative ideas that have an impact on our society, providing capital, knowledge and networking.

Investment focus

Software, Artificial Intelligence, Internet
Seed, Pre-Seed
Portugal, United States

Portfolio highlights

pleez — Pleez offers Restaurant's an optimisation of their menu within Delivery Platforms, so that they can have a revenue increase up to 25%.
Volup — Volup is a premium food delivery app that partners exclusively with top-tier chefs and restaurants.
Relive — Relive is empowering the next generation of real estate entrepreneurs, with a mobile app that allows them to work for themselves, from anywhere, while saving time and earning commissions faster.

Beta Capital was founded in September 24, 2003 by a group of entrepreneurs and enthusiasts for innovation with the goal of financing innovative start-ups.The company is a specialist venture capital firm investing in new technology-based projects at their early stages (seed capital and start-ups).We work in close cooperation with severalPortuguese entities belonging to the Scientific and Technological National System (which includes Universities and R&D Centres) in order to foster scientific innovation.Typically we provide hands-on support to our portfolio companies by building relationships with entrepreneurs based on mutual respect and contributing with our experience to achieve success.

Investment focus

VoIP, Software, Wireless
Seed, Funding Round
Portugal

Portfolio highlights

LoopOS — LoopOS is a comprehensive Circular Economy ERP system designed to optimize and streamline multiple processes including buybacks, returns, trade-ins, repairs, and consumer-to-consumer transactions. It focuses on providing tools to measure the impact of the activities.
PFx Biotech — PFx Biotech transforms food through bioinnovation by creating sustainable and nutritional alternative protein solutions.
Vawlt — Simplify your company's transition to the cloud, improve security standards, and optimize storage resource usage.

Ability to open doors on opportunities (potential clients/strategic partners/suppliers/etc). Add market credibility, something missing in many start-ups.Know-how that can save you time, money and unnecessary stress and worry. Ability to complement the existing management team, filling gapsThey understand the difficulties andhardships of starting and building a business. They are motivated to work with you on the building process, and not just wait for the end result

Investment focus

Health Care, Fitness, Wellness
Seed, Pre-Seed, Funding Round
Portugal, United States, United Kingdom

Portfolio highlights

Abtrace — Transforming Clinical Decisions through Data
sheerME — SheerME is Revolutionising the way people find, book, and pay for their Wellness and Beauty services powered by a benefit-based walletOur approach is based on Discovery, Transaction & Reward to create more online visibility, reach, conversion into new business, loyalty, and frequency through our wallet and cashback ecosystem, to all ourpartners in the beauty and wellness sectors.This made us a fresh and different option in this sector where there are mainly SaaS players, and we bring marketplace with no monthly fee, only a commission for business sent through our owned and partner channels.
ChemiTek — Certified & sustainable solutions for industrial maintenance. We have the solutions you need!

Boost VC: The Pre-Seed Fund Making Sci-FI a Reality. Investing in crypto, virtual reality, augmented reality, AI, Ocean Tech, Space Tech, human augmentation, exoskeletons and more.

Investment focus

Software, Virtual Reality, Blockchain
Seed, Pre-Seed, Funding Round
United States, Canada, United Kingdom

Portfolio highlights

forml — Use forml to build and integrate intelligent workflows for any task in seconds, with flexible integrations.
ego AI — Building intelligent, embodied characters that bring human-like behavior to games, simulations, and beyond.
Neurvona — AI Digital Twin Personas

Pedro Lourenço

Investment focus

Consumer, Analytics, Insurance
Angel, Pre-Seed
Portugal, United States

Portfolio highlights

MindProber — Not all impressions are created equal. Understand the emotional impact of your content. Learn about Mediaprobe - Next-gen media measurement.
Habit — Habit's mission is to bring context and meaningfulness to the way insurance is sold. We connect brands with insurers to enable the best way to distribute insurance - on digital.

We deploy early stage capital to fuel the growth of need-driven health technology companies.

Investment focus

Health Care, Artificial Intelligence, Medical
Seed, Pre-Seed, Series A
United States, United Kingdom, Germany

Portfolio highlights

Datamonk — AI-powered PACS migration platform that automates secure and fast transfers of medical imaging data. Migrate up to 10TB per day and use AI agents for data validation and quality assurance.
io Health — Io Health Technologies LLC provides AI-driven tools for home health documentation and workflow automation in healthcare.
Sober Sidekick — Gamified peer to peer support

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

doc-doc — Accede a los mejores especialistas en medicina, cuando y donde quieras.
Jiseki Health — Jiseki is built on the belief that families and communities need and deserve a safety net, and to have peace of mind when things go wrong. We provide access and delivery of key advice, help, products and services through highly scalable SMS technology, powered by a combination of professionals and AI, and sold as a portable life benefit package..Text #help to 543210, to discover Jiseki services.
Biome Analytics — Providing doctors and hospitals precision insights needed to deliver better care at a lower cost. Cardiovascular program improvement, clinical performance applications, precision clinical and financial insights.

Pathena is an investment firm engaged on boosting the success of information technology and digital biomedical companies.

Investment focus

B2B, Made to Order, Marketing
Series A, Seed, Series C
Portugal, Germany

Portfolio highlights

BIZAY / 360imprimir — • Bizay has empowered more than 1 Million SMB’s to grow their businesses during the last 5 years.• Bizay is a tech-based B2B Marketplace for made-to-order products. Running a fabless business model (no capex), it leverages on the idle capacity of production partners to meet the needs of the SMB’s.• Started on printing, packaging, textile andprofessional products and now applying the same model in furniture, food and 3D printing (amongst others).• 360imprimir / 360onlineprint - rebranded to Bizay - Your bussiness your way - to reflect the unlimited product categories. • Bizay is the customer facing brand (the SMB’s do not meet the production partners) and its tech platform manages the production by: o Using data and algorithms to aggregate different orders and to decide in which suppliers to produce them, driving huge efficiency and speed gains. o Enabling full tracking of the orders in the different production partners and automating pre-production processes.• Bizay differentiates themselves from other players by offering: o Online configuration of the products (options to customize and personalize). o Competitive pricing for small and medium orders (similar price per unit as for large orders), 48 hours of delivery time (instead of several weeks) and guaranteed quality (customer-facing brand ensuring high quality levels). o Integrated value chain in a single offer (on-demand design services provided by external providers).• Originally selling in Portugal, Spain, Brazil and México, the company raised B round of 18m€ one year ago (communicated in April) in order to launch new countries.• 17 new countries were launched in 2019 simultaneously (including DE, FR, UK and USA).• In 2019, 8 months of trading in the new countries confirm: o Competitiveness pricing of their offer in all the market. o Market deepness and sound acquisition metrics.
Promptly — Health Analytics Patient Report Outcomes, Health Care, Value based health
NVision Imaging Technologies — NVision Imaging Technologies is leveraging advances in quantum physics to enable the first routine, convenient and affordable use of Magnetic Resonance Imaging (MRI) for assessing early patient response to cancer treatment at the metabolic level.

Teak Capital is a venture capital management firm based in Malaysia. The company believes in empowering entrepreneurs to think big and at the same time mastering the essential building blocks of managing a business from practicing right governance, holistic understanding of company financials, and seeking opportunities for the business.Teak lendsits expertise and advice in corporate matters and add value by giving new perspective to entrepreneurs in developing and strategizing for their business growth.

Investment focus

Baby, Biofuel, Children
Seed, Series D
Malaysia, Portugal, United States

Portfolio highlights

DigiLens — DigiLens is an innovator in holographic waveguide display technology for extended reality (XR).DigiLens has developed a patented optical platform and photopolymer technology that delivers best-in-class solutions using a unique, low-cost contact-copy manufacturing process. DigiLens enables OEM partners to design and build XR-enabled devices for theglobal automobile, enterprise, consumer, avionics, and military industries.
BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.
Applecrumby & Fish — Applecrumby & Fish is an online and offline baby store that offers various brands of baby products available both locally and internationally. The baby products are classified under the categories: bath and skincare, food and health, feeding, baby gear, diapers and potty, playroom, maternity, and school.Putto, Brush Baby, Tommee Tippee,Hot-Kid, Nordic Naturals, Annie’s Organic, Zoli, Munchkin, Avent, Clevamama, Attitude, Potette Plus, The First Years, Renova, Peaceable Kingdom, Mega Bloks, Emma-Jane, MooGoo, Stephen Joseph, and Thinkbaby are some of the brands available in Applecrumby & Fish’s stores.Applecrumby & Fish was founded in 2011 and is based in Selangor, Malaysia.

Shilling is an early-stage venture capital firm backing exceptional founders from the start.Shilling invests in a wide range of verticals and seeks out the biggest opportunities across all B2B and consumer categories. Leveraging the concept of Founder LPs, Shilling brings much more than capital and offers through its Shilling Platform, directaccess to successful founders and executives of leading companies. This platform supports entrepreneurs in validating and developing their ventures, which then accelerate their growth into global markets.

Investment focus

Information Technology, Software, Internet
Seed, Pre-Seed, Series A
Portugal, Spain, United States

Portfolio highlights

Cafler — Your car's personal assistant. Ask for a Cafler now, we move your car for you!
Nilo — Nilo is a collaborative 3D platform that works across desktop, mobile, Discord, and Telegram. It combines generative AI with world-building tools, allowing users to generate assets, characters, animations, and code from natural language or drawings. The result: a radically simplified creation experience that lowers the barrier to entry andaccelerates how quickly new ideas can be built, tested, and shared.It’s creation at the speed of culture: whether spinning up a game inspired by today’s viral sound, turning a group chat joke into a playable world or crafting a custom hangout, Nilo transforms imagination into interaction — instantly and collaboratively.Nilo’s key features include:Text-to-3D generation: Create characters, environments, and code from prompts or images. Browser-Based: Nilo runs entirely in your browser - no installs, no downloads, no friction. Voice-enabled coding: A built-in AI-powered code editor that supports spoken commands and natural language for playful, social programming. Real-time multiplayer: Co-create and play with friends instantly.Nilo was founded in April 2024, bringing together veterans from Fortnite, Twitch, YouTube, Snapchat, Microsoft, Adobe, Blizzard, VRChat, Rec Room, and major VFX projects such as Avatar and Star Wars.
specter automation — Construction is the second least digitized sector in the world with 96% of all data being unused. Although detailed planning data is created upfront, a lack of suitable digital tools prevents its transfer to the construction site. SPECTER’s web-based construction management software uniquely incorporates the core components of constructionplanning, reducing the organizational burden on construction management and helping to meet project timelines and budgets.

Jeremy Hendon

Investment focus

Apps, Fitness, Big Data
Pre-Seed
Portugal

Portfolio highlights

Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Michael Chang

Investment focus

Apps, Fitness, Big Data
Pre-Seed
Portugal

Portfolio highlights

Virtuleap — Virtuleap combines neuroscience and virtual reality to help increase attention levels, and address cognitive illnesses, disorders, and learning challenges. We have created a library of VR games designed by neuroscientists in order to test and train a range of cognitive abilities and make that data accessible through our enterprise platform. Ourfirst paid client is the AARP, and we are now working with leading institutions, like the VA Health Care System and the Pacific Brain Health Center, to validate our solution as an effective diagnostic and treatment for attention deficit and cognitive decline.

Bionova Capital, previously known as Hovione Capital, is a healthcare-focused venture capital firm, investing in early-stage life science companies. It was founded in 2015 by the shareholders of Hovione, one of the largest pharmaceutical companies in Portugal, with manufacturing and research operations in USA, Ireland, China and Portugal. BionovaCapital invests in groundbreaking therapeutics, medtech and digital health startups across Europe.

Investment focus

Biotechnology, Hospital, Health Care
Seed, Funding Round
Portugal, United Kingdom

Portfolio highlights

Delox — Delox is a spin-off of the Faculty of Sciences of the University of Lisbon (FCUL), whose goals consist in the design, development, and production of a vast portfolio of automatic biodecontamination robots. Target applications include the sterilization of medical devices in hospitals, health centers and field hospitals (for humanitarian missions,catastrophe situations, and war zones); room biodecontamination in hospitals, pharma, food industry and space; and laboratory equipment biodecontamination.
CellmAbs — Pharmaceutical Company, Biotechnology
Adapttech — Adapttech is a biomedical company that uses innovative, smart and wearable technologies to deliver full adaptation and comfort to people with physical limitations.

InterCapital is an investment firm focused on early-stage ventures. InterCapital cooperates with outstanding Entrepreneurs, promoting innovative ideas and business models, leading to positive social and environmental impact.

Investment focus

SaaS, Human Resources, Biofuel
Funding Round, Seed
United Kingdom, Portugal

Portfolio highlights

Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

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