Top 35 Enterprise VC Funds & Investors in Puerto Rico (October 2026)

Portfolio highlights

• Luminoah — Discover Luminoah Flow, the world's smallest enteral nutrition delivery system designed for your active lifestyle. Empower your nutrition journey today.
• Cloverleaf AI — Cloverleaf AI turns 1.5 million government meetings into early buying signals, so you reach buyers before the RFP. Government sales intelligence for B2G sellers.
• Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Portfolio highlights

• Wirelane — Driven by the mission "We empower people to move towards a clean future", Wirelane has been designing sustainable mobility since 2016 and is developing innovative complete solutions for the construction, operation, and marketing of charging infrastructure. Wirelane provides its customers with all the necessary service modules, rangingfrom cutting-edge charging technology to a digital management and billing platform, as well as comprehensive installation and operation services.
• Flashcookie — Flashcookie is an on-demand merchandise for independent artists based in Buenos Aires, Argentina.
• Solve Therapeutics — Solve Therapeutics is a biopharmaceutical company that develops Antibody Drug Conjugate and Bispecific Therapeutics. The company was founded in 2021 and is headquartered in Belmont, California.

Portfolio highlights

• Toteat — Headquarters located at Vitacura 2771, of. 504, Las Condes, Santiago de Chile
• Kiwi — Kiwi is a leading platform that helps Latinos living in the US, who may have limited credit data and access to capital, build credit history through unsecured lines of credit and alternative credit builder programs. As the fastest-growing minority segment in the US, the Latino market is expected to reach over 100 million in the next few decades.Our mission is to empower Latinos by providing tools and resources to establish credit, access capital and save money.
• BackChannel — BackChannel is an online B2B platform for inventory transactions and for buying and selling online goods.

Portfolio highlights

• IMUA — Follow us @imua
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Valinor — Institutional capital solutions at the intersection of credit and blockchain

Portfolio highlights

• BUREA (Better Ideas Holdings) — BUREA is a mobile platform to capture engagement & analytics for offline sales.BUREA captures all the consumers’ transactions no matter where they happen: grocery store, gas station, even a bakery by engaging and incentivizing users to upload their shopping receipts in exchange for cash. These receipts are then analyzed and categorized tounderstand what these consumers are buying And applying machine learning and different algorithms to this data.
• Autoimmunity BioSolutions — ABS is developing a next-generation, immuno-corrective therapy to restore normal immune function in a genetically-defined subpopulation of autoimmune disease patients.

Portfolio highlights

• GovSky — Building cybersecurity technology to secure America’s supply chain.
• Kashable — Kashable is on a mission to help employees handle unexpected expenses and tackle high-interest debt. Our platform provides financial wellness solutions that help employees to preserve retirement savings, improve their credit scores, and navigate financial hardships responsibly. Plus, Kashable provides employees access to free Financial Literacy resources to help plan for the future.
• Carbon Robotics — The Carbon Robotics LaserWeeder solves one of agriculture's biggest problems: weed control. Laserweeding kills weeds without herbicides or tilling by harnessing computer vision and thermal energy to identify and destroy weeds at the meristem. It's healthier for crops and land, and safer for farmers.

Portfolio highlights

• InsideDesk — Reduce AR days, boost collections, and streamline billing operations with InsideDesk's centralized revenue cycle management platform.
• CWX — CLOUDWERX provides elite engineering resources to accelerate your business.
• Lightworks — Lightworks is a Canadian consulting company that focuses on enterprise AI infrastructure and control systems. The company works with the biggest and most regulated companies in the world to plan, manage, and safeguard AI-powered systems.

Portfolio highlights

• Digs — Digs is an easy-to-use collaboration software solution for professionals in residential home building that provides more efficient file storage, collaboration, and homeowner handoff for home construction projects. Try Digs for free today!
• Shoutcast Net — Stream from any device & protocol to any device & protocol. Very low latency 3 sec. AutoDJ & restream to Facebook, Twitch, YouTube included. 7 days trial!
• Midsummer Studios — Midsummer Studios is a independent, well-funded and committed to building a new kind of studio.

Portfolio highlights

• OP_NET — OPNET is a Bitcoin Layer 1 metaprotocol that enables smart contracts to function directly on the Bitcoin blockchain, without the use of sidechains or Layer 2 solutions.
• Modveon — The verified operating system for the modern nation state. Digital identity. Trusted communities. Sovereign financial rails. AI-native services.
• BridgePort — Crypto institutional middleware for off-exchange settlement. BridgePort's coordination layer connects exchanges and custodians for trading firm interoperability

Portfolio highlights

• Variational — Go long or short with leverage on memecoins, DEX pairs, pre-launch tokens, points markets, and more.
• Hyperdrive — The liquidity layer for RWAs. Scaling lending by eliminating the need for oracles, AMMs, and external liquidators.
• Open Campus — The Open Campus is a community-driven protocol that leverages the power of blockchain and invites all to build the future of education by putting the power of learning back in the hands of educators, students, and the community.

Portfolio highlights

• IMUA — Follow us @imua
• Wert — Making purchasing of NFTs seamless and not requiring users to have crypto.
• Outland — Criticism and conversations about art, technology, and NFTs

Portfolio highlights

• Murmuratto — Get 1% Better Everyday. Workflow software that drives Innovation + Operational Excellence for manufacturing and regulated industries.
• Seis Dedos Studio — Estudio Seis Dedos is a creative studio that specializes in developing ideas through various design and digital services. Their expertise includes web development, editorial design, corporate identity, animation, illustration, online advertising, and digital marketing. They work on projects such as websites, eCommerce platforms, brand identity, andinfographics for clients like Hómini Studio, IPJ, Centro Latinoamericano de Juventud, and Estudio Ferrer Napoleone. Overall, they offer comprehensive creative solutions to help brands build their visual presence and marketing strategies.
• Inmigración Virtual — Virtual Immigration is a law firm that offers immigration services in the United States and Puerto Rico, both virtually and in person. Its purpose is to provide accessible and secure assistance to people from all over the world interested in obtaining immigration relief in the U.S.

Portfolio highlights

• LYNC — The first consumer centric Layer 2 on Move
• Releap Protocol — Releap Protocol is a decentralized social graph on Sui
• Scallop — Scallop is the pioneering Next Generation peer-to-peer Web3 Decentralized Finance lending Money Market.

Portfolio highlights

• GooseFX — GooseFX is your premier destination for everything
• Neftify — Neftify is a blockchain powered platform for crowd sourcing game assets and loaning them to players.
• Banksea Finance — Banksea Finance is an AI-powered NFT Oracle and NFT Pool-based Lending platform.

Portfolio highlights

• Wizzwoods — 1st pixel farm game integrates interchain capabilities with a SocialFi twist.
• SuperIntent — SuperIntent is a cryptocurrency AI app that streamlines on-chain earning tactics. Developed on a multi-agent framework with abundant yield sources.
• SuperGaming — At SuperGaming, we are putting India on the global gaming map.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Key Media — Key Media is an events and niche publishing company.
• Veridic Solutions — Veridic is a leading developer of cloud-based software. We combine talented minds with learning and innovation to solve the most complex issues. Our cloud certified engineers are uniquely positioned to serve your cloud projects
• Mobile Vascular Physicians — Mobile Vascular Physicians is a concierge vascular and interventional service (commonly called 'Special Procedures'), with a concentration in lower extremity venous and arterial disease.

Portfolio highlights

• Novastro — Building the PayFi layer for stablecoin-powered payments, settlement, and real onchain financial utility.
• Shiba Inu Coin — Shiba Inu Coin is an Internet Publishing Company.
• Router Protocol — Router Protocol is a Cross Chain Bridge. Currently live on Ethereum, Polygon, and more. Building an interoperable cross chain future of the blockchain ecosystem.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.
• NexGen Cloud — Discover NexGen Cloud's innovative AI cloud solutions designed for seamless scalability, high performance and robust security. Lead AI innovation with NexGen Cloud.

Portfolio highlights

• Chomp — Chomp is a social network platform that focuses on on question-and-answer with prediction-based systems.
• Techdollar — Techdollar operates a private credit platform that originates and underwrites loans secured against private company equity. The service enables late-stage startup founders, employees, and institutional investors to unlock liquidity from their shares without triggering a taxable sale or losing long-term upside.
• ARO Network — ARO Network is a decentralized edge cloud platform focusing on power peer-to-peer content delivery.

Portfolio highlights

• Qredo — Qredo is a cross-chain protocol for asset managers and traders active in the digital asset markets. Using our institution-grade, layer 2 infrastructure, investors can now hold all their crypto assets securely in one place, with unlocked access to a wide range of liquidity venues and DeFi yield opportunities.
• AuDIGENT — AuDIGENT is an audience intelligence platform that provides brands with actionable data, analytics and insights that optimize the targeting, engagement and ROI of online, mobile and social video ads while opening up new revenue streams for artists and other social influencers. AuDIGENT's platform allows brands to discover, monitor and targetaudiences that drive media performance. AuDIGENT's platform empowers artists and influencers to tap into the tools and technology needed to monetize their social influence and fan engagement. AuDIGENT's executives, data scientists, developers and operations team are in New York, Philadelphia and London. For more information visit AuDIGENT.com
• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Neosoul — NeoSoul uses an open architecture with autonomous agents operating under user-defined constraints to link agent intelligence, deterministic capital controls, and verifiable market execution.
• ORO — ORO is an AI-powered DeFi companion that lets users manage, trade, stake, lend, and research crypto assets through natural-language conversations, ORO aims to simplify onchain finance by bringing portfolio management and DeFi actions into one conversational interface.
• GAEA — GAEA is a decentralized artificial intelligence training network and data infrastructure platform focused on building a comprehensive multimodal emotional database.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients
• San Jorge Children & Women's Hospital — San Jorge Children & Women's Hospital provides health care to children and women and enables excellent services to all patients.

Portfolio highlights

• Magma — Native liquid staking and MEV, powered by the fastest block engine in crypto. Earn yield and points, live on @Monad Mainnet.
• Rover — Bitcoin Liquid Staking on @BotanixLabs
• Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.

Portfolio highlights

• 3DOS — 3DOS operates as a peer-to-peer manufacturing network. It allows brands, influencers, artists, or inventors to take a design to product in hours, by protecting royalties and allowing those products to be made on demand globally via a 3d manufacturing network.
• InstaSecure — InstaSecure develops a security platform designed to protect cloud assets. It allows users to quickly build a data perimeter to prevent attacks from misconfigurations, compromised credentials, and
 future unknown threats.
• FaradaIC Sensors — FaradaIC Sensors is to commoditize gas sensors and provide flexible gas sensing at a cheap cost for the expanding market of IoT applications.

Portfolio highlights

• Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
• Mauve — Fully Compliant, Non-Custodial Exchange
• Center — Start point for your next NFT app.

Portfolio highlights

• IMUA — Follow us @imua
• Orb Labs — We make any transaction gasless and bridgeless, restore fungibility and fluidity of stablecoin, and connect onchain accounts with the offchain world.
• Flare Network — Flare is a full-stack layer 1 solution designed for data intensive use cases.

Portfolio highlights

• LNT — LNT provides a Bitcoin Taproot-based token system that allows basic asset creation and transfers with limited available details.
• OmenX — OmenX operates a leveraged prediction trading platform that converts real-world events into markets that users can trade. The platform supports outcome-based contracts that reference sports, politics, economics, and other event categories. Users speculate on event outcomes using cryptocurrency collateral and access leverage to amplify directionalexposure. OmenX focuses on making outcome-based trading liquid and flexible for a global user base. The service targets crypto traders, derivatives users, and others interested in event-driven strategies.
• inspoloom — Inspoloom is an AI-powered fashion content platform that enables creators, influencers, and brands to transform fashion ideas into scroll-stopping, shoppable visual content and videos in minutes — not days. The platform leverages generative AI to produce complete outfit series, high-fidelity fashion imagery, and social-ready short videos,eliminating the need for traditional photoshoots, makeup, location scouting, or physical production. At the core of Inspoloom's technology is an AI fashion engine that takes a vague creative concept — such as "Winter Parisian Chic" or "Parisian Quiet Luxury" — and generates endless outfit variations in under 15 seconds, maintaining consistent model identity, aesthetic coherence, and style accuracy across the entire series. Each generated look is matched to real, in-stock retail products from brands and marketplaces, making every outfit shoppable with direct product links and affiliate monetization capabilities. Inspoloom serves fashion content creators, stylists, social media managers, and e-commerce brands seeking a scalable, cost-efficient content production pipeline. The platform's output includes outfit lookbooks, lifestyle imagery set in contextual environments (such as Parisian street scenes), and high-performing short-form videos formatted for popular social platforms. By converting a single idea into a complete content series with embedded commerce links, Inspoloom bridges the gap between fashion inspiration and affiliate-driven monetization.

Portfolio highlights

• BUREA (Better Ideas Holdings) — BUREA is a mobile platform to capture engagement & analytics for offline sales.BUREA captures all the consumers’ transactions no matter where they happen: grocery store, gas station, even a bakery by engaging and incentivizing users to upload their shopping receipts in exchange for cash. These receipts are then analyzed and categorized tounderstand what these consumers are buying And applying machine learning and different algorithms to this data.

Portfolio highlights

• AEON — Powering #agenticeconomy #x402 | AEON is settlement layer bridging autonomous AI interactions (A2A & A2M) with real-world value flows. Backed by @yzilabs $AEON
• Slinky Network — Slinky Network provides an on-chain marketplace and payment protocol that connects AI agents and applications with third-party APIs. The company offers the SlinkyLayer platform, which wraps developer endpoints as discoverable skills and exposes them through an x402 pay-per-execution interface. Each API call triggers a non-custodial on-chainmicropayment, settling in the same request loop using networks such as Base and BNB Chain. Developers set prices, earn a defined revenue share, and receive instant payouts to their wallets without subscriptions or custodial holds. AI agents authenticate via wallet signatures, enabling autonomous, machine-to-machine access and payment without traditional logins or credit cards. The platform also records call ratings on-chain to provide portable, verifiable reputation for services.
• Shanghai Molian Technology — Shanghai Molian Technology is an intelligent agent communication infrastructure platform

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
• Flowcarbon — Flowcarbon's versatile team merges investment banking, project finance, tax credit and other financial markets expertise to streamline access to creative capital solutions for the world’s most innovative companies in the infrastructure, decarbonization, and other niche sectors. Flowcarbon is headquartered in New York, United States and wasfounded in 2021.
• IntentX — The Future of Decentralized Derivatives

Portfolio highlights

• IMUA — Follow us @imua
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — The full stack AI GTM solution. We help your brand grow on autopilot.

Portfolio highlights

• Sol — Sol a company focused on building tools to power team collaboration and collective productivity.
• Nyayanidhi — Reforming India's Litigation/Judicial System
• Protein Pantry — Protein Pantry is an Indian clean-label food brand offering ready-to-cook, vegetarian, high-protein tikkis and chaaps