Top 25 Enterprise VC Funds & Investors in Puerto Rico (June 2026)

Portfolio highlights

• Luminoah — Discover Luminoah Flow, the world's smallest enteral nutrition delivery system designed for your active lifestyle. Empower your nutrition journey today.
• Cloverleaf AI — Transforming 1.5 million government meetings into 10 minutes of actionable information daily to help companies gain an edge with RFPs.
• Apira Technologies — Apira Technologies provides a persona platform that enables users to pilot photorealistic avatars and scenes over desktop video conference systems and streaming platforms.

Portfolio highlights

• Kaia — Kaia is a public blockchain that utilizes Byzantine Fault Tolerance (BFT) for enhanced reliability and performance.
• Variational — Go long or short with leverage on memecoins, DEX pairs, pre-launch tokens, points markets, and more.
• Hyperdrive — Hyperdrive delivers investment growth strategies utilizing a portfolio-centered approach.

Portfolio highlights

• VirgoCX — We make crypto trading safe, easy, and affordable for Canadians. Buy Bitcoin, Ethereum and 60+ Cryptocurrencies with competitive pricing, Free cash in and out, instant funding, and timely customer service.
• AllScale — AllScale is a next-generation platform empowering small businesses to scale globally faster with stablecoin. Payroll: Automate cross-border payroll in stablecoins—simplify contractor payments, eliminate costly intermediaries, and ensure instant global delivery.Invoicing: Create, e-sign, and send professional contracts and invoices in seconds.Get paid by clients in their preferred method and instantly receive stablecoin—maximizing liquidity, minimizing friction.Social Commerce: Transform your followers into customers. Embed a dynamic AllScale biolink on your social profiles, showcase your offerings, and securely collect instant stablecoin payments directly from your audience.
• MIDL — MIDL is a digital finance company that offers EVM compatibility, functionality of Ethereum dApps to Bitcoin users.

Portfolio highlights

• GENCY AI — Gency AI is a Web3 platform for privacy-focused, verifiable digital ads using encrypted data and proof-based tracking.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.
• Interstate — Interstate is an Ethereum pre-confirmation protocol. It aims to make Ethereum transactions near-instant and allow applications to self-order while maintaining full composability with L1.

Portfolio highlights

• Magma — Magma is a decentralized liquid staking protocol built on the Monad Network, an Ethereum-compatible Layer 1 blockchain.
• Rover — Rover is a liquid staking protocol on Botanix that exchanges Bitcoin for rovBTC.
• Neptune Protocol — Neptune Protocol is a decentralized lending platform. It enhances capital efficiency by enabling customers to obtain liquidity in a secure manner.

Portfolio highlights

• Wirelane — Wirelane is a full service provider in the field of electric mobility. The company is currently active in 5 countries (D, F, S, NL, CH) and has experience with large industrial customers (VW, Vattenfall, Bouygues and others). In addition to their software solutions, they also offer specially developed charging stations that set standards throughthe use of advanced technology such as radar sensors and tap payment. The company works with customers from all industry sectors to develop solutions for tomorrow’s mobility needs. Wirelane is one of Europe’s leading specialist providers of hardware, software and app solutions.
• Flashcookie — Flashcookie is an on-demand merchandise for independent artists based in Buenos Aires, Argentina.
• Solve Therapeutics — Solve Therapeutics is a biopharmaceutical company that develops Antibody Drug Conjugate and Bispecific Therapeutics. The company was founded in 2021 and is headquartered in Belmont, California.

Portfolio highlights

• Key Media — Key Media is an events and niche publishing company.
• Veridic Solutions — Veridic is a leading developer of cloud-based software. We combine talented minds with learning and innovation to solve the most complex issues. Our cloud certified engineers are uniquely positioned to serve your cloud projects
• Mobile Vascular Physicians — Mobile Vascular Physicians is a concierge vascular and interventional service (commonly called 'Special Procedures'), with a concentration in lower extremity venous and arterial disease.

Portfolio highlights

• Biconomy — Blockchain transactions made simple. Enable Gasless meta-transactions, instant cross-chain transfers, easy layer 2 onboarding & zero failed transactions
• Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
• Router Protocol — Router Protocol is a Cross Chain Bridge. Currently live on Ethereum, Polygon, and more. Building an interoperable cross chain future of the blockchain ecosystem.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.
• NexGen Cloud — Discover NexGen Cloud's innovative AI cloud solutions designed for seamless scalability, high performance and robust security. Lead AI innovation with NexGen Cloud.

Portfolio highlights

• Exocore — Exocore is the layer one blockchain for aggregated security.
• Optimum — Optimum constitutes a decentralized, high-performance memory infrastructure tailored for use across various blockchains.
• Doppler Finance — Doppler Finance is a yield-earning platform that unlock earning opportunities within the XRPL ecosystem

Portfolio highlights

• Decent Labs — We are rebuilding trust in technology. Decent Labs is developing a more transparent and equitable society by creating startups at the cross-section of financial technology and digital rights.
• Flowcarbon — Flow Carbon uses blockchain technology to put carbon offset credits on-chain, accelerating the creativity and scalability of climate change solutions. Flow Carbon is headquartered in New York, United States and was founded in 2021.
• IntentX — The Future of Decentralized Derivatives

Portfolio highlights

• Akave Cloud — Akave is a decentralized data management network that supports the next generation of data-driven apps and marketplaces.
• HyperLend — HyperLend is the operator of a money-market platform using the EVM chain to make lending and borrowing digital assets efficient and secure.
• ARO Network — ARO Network is a decentralized edge cloud platform focusing on power peer-to-peer content delivery.

Portfolio highlights

• Sepana — Sepana develops search technologies designed to make it easy for people, communities, applications, and protocols to discover Web3 content. Founded in 2021, Sepana's API allows developers to build search-as-a-service functionality directly into their apps.
• Mauve — Fully Compliant, Non-Custodial Exchange
• Optic — Optic monitors blockchains to reveal the origins of any NFT and how it’s been reimagined, remixed, or copied.

Portfolio highlights

• Abartys Health — abartysHealth provides simple, smart and secure healthcare data management solutions for life sciences companies, health plans and patients

Portfolio highlights

• Rails — Experience unparalleled speed and efficiency with Rails, your go-to platform for lightning-fast crypto perpetuals trading.
• PocketHealth — Get early access to your medical imaging results. Trusted by more than 2M patients and 900 hospitals and clinics.
• CWX — CWX is a full-service enterprise cloud consulting company.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Wert — Making purchasing of NFTs seamless and not requiring users to have crypto.
• Outland — Criticism and conversations about art, technology, and NFTs

Portfolio highlights

• Qredo — Qredo is a cross-chain protocol for asset managers and traders active in the digital asset markets. Using our institution-grade, layer 2 infrastructure, investors can now hold all their crypto assets securely in one place, with unlocked access to a wide range of liquidity venues and DeFi yield opportunities.
• AuDIGENT — AuDIGENT is an audience intelligence platform that provides brands with actionable data, analytics and insights that optimize the targeting, engagement and ROI of online, mobile and social video ads while opening up new revenue streams for artists and other social influencers. AuDIGENT's platform allows brands to discover, monitor and targetaudiences that drive media performance. AuDIGENT's platform empowers artists and influencers to tap into the tools and technology needed to monetize their social influence and fan engagement. AuDIGENT's executives, data scientists, developers and operations team are in New York, Philadelphia and London. For more information visit AuDIGENT.com
• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• Digs — Digs is an easy-to-use collaboration software solution for professionals in residential home building that provides more efficient file storage, collaboration, and homeowner handoff for home construction projects. Try Digs for free today!
• Streem — Easy AR-powered remote video support & communication platform with AI data capture to get the job done from anywhere. Streem is better than being there.
• Midsummer Studios — Midsummer Studios is a independent, well-funded and committed to building a new kind of studio.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.

Portfolio highlights

• OmenX — OmenX operates a leveraged prediction trading platform that converts real-world events into markets that users can trade. The platform supports outcome-based contracts that reference sports, politics, economics, and other event categories. Users speculate on event outcomes using cryptocurrency collateral and access leverage to amplify directionalexposure. OmenX focuses on making outcome-based trading liquid and flexible for a global user base. The service targets crypto traders, derivatives users, and others interested in event-driven strategies.
• DGrid AI — DGrid AI operates a decentralized AI inference network built on Web3 infrastructure. The platform provides an AI RPC layer that routes requests across distributed network nodes to run large language models. It offers a unified interface for AI app developers to access many LLMs and build AI-powered applications. The network uses tokenizedincentives and DAO governance to reward node operators and community participants. DGrid AI focuses on scalable on-chain inference and monetization of AI models for open, community-powered usage.
• BIO Protocol — The BIO Protocol (BIO) allows onchain scientific communities to fund, build, and co-own research and products in specific biomedical domains including lifespan, brain health, and rare disorders. BIO, founded by senior VitaDAO members, empowers worldwide communities of scientists, patients, and investors to take science into their own hands andbring solutions to life more effectively than traditional pharmaceutical companies.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• PUML Better Health — Earn cryptocurrency and get rewarded for completing gamified physical and mental health challenges. Available on both Play Store and App Store.

Portfolio highlights

• Tea — Learn more about the tea protocol and how to unlock the rewards for previous and future open-source software contributions.
• Casper Labs — Casper Labs powers scalable, secure & decentralized blockchain solutions for businesses, with the most flexible and customizable architecture on the market