Top 50 Health Care VC Funds & Investors in Japan (June 2026)

Portfolio highlights

• Sotas — Sotas provides services to chemical trading companies and bridges the gap between raw material producers and consumers.
• PartnerProp — PartnerProp is a PRM tool with outstanding potential and a wide variety of capabilities that resolves all partner business difficulties.
• Infobox — Infobox is a sales data platform that includes every detail from market research to creating a list of companies and contacting decision-makers.

Portfolio highlights

• Metro Weather — Metroweather is a venture from Kyoto University that develops a high-performance Doppler lidar that measures the direction and speed of wind several tens of kilometers away from minute movements of fine particles in the atmosphere. We aim to contribute to the safety of the sky by completing a three-dimensional wind map, which has never beenrealized,based on years of research at the Kyoto University Research Institute for Sustainable Areas.
• Good News — Good News is a staffing agency that provides recruitment, public relations, and human resource management services.
• Okuma Diamond Device — Ookuma Diamond Device Co., Ltd. | Creating a next-generation semiconductor industry from Japan, driven by the mission to support the decommissioning of Fukushima Daiichi Nuclear Power Plant.

Portfolio highlights

• Fondi — fondi is a completely new English conversation communication service that allows you to live a virtual communal life with the world.
• Taian — Taian, which specializes in bridal industry services and software. They also provide ''Concept Marry,'' which allows couples to design invites and seating charts that match their wedding theme, as well as display guest information on Oiwaii.
• Knowledge Work — Knowledge Work specializes in the development and sales of software for companies.

Portfolio highlights

• CastBio — Castbio specializes in antibody-drug conjugate-based drug discovery research and development. Along with medications, it also creates research reagents, medical equipment, in vitro diagnostic items, and offers drug discovery consulting.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.
• Reborna Biosciences — Reborna Biosciences provides research and development in the field of genetic diseases. The company develops therapeutic options for area of unmet medical needs in genetic rare disease. The company's technology enables low-molecular compounds to target ribonucleic acid. The company provides new disease-modifying drugs for patients sufferingfrom rare genetic diseases including spinal muscular atrophy.

Portfolio highlights

• NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
• Sonire Therapeutics — Sonire Therapeutics provides High-Intensity Focused Ultrasound treatment for cancer.
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• Todoker — Todoker is a baggage delivery convenient service providing company.
• CREO Bioscience — Cleo Bioscience is a Biotechnology company.
• Fabric Tokyo — FABRIC TOKYO is a Japanese startup provides a direct-to-consumer custom-made apparel brand. (former-company name Lifestyle Design Co., Ltd.). It enables customers to save their sizes, idea fabrics, and favorite designs, allowing them to make their original clothing later.FABRIC TOKYO was founded in 2012 by Yuichiro Mori and is based in Tokyo,Japan.

Portfolio highlights

• ElleThermo — elleThermo aims to implement Semiconductor-Sensitised Thermal Cells (STCs), an energy conversion technology that can generate electricity from unused waste heat above room temperature.
• Aeterlink — Aeterlink is a wireless device maker and developer. They applied their technology to fields such as FA, robots, smart houses, and medicine and developed practical level technologies such as elemental technology that can wirelessly supply power.
• Nanofiber Quantum Technologies — Discover how NanoQT builds the foundation for scalable quantum computing with nanofiber cavity-QED technology and high-fidelity quantum connectivity.

Portfolio highlights

• Surv Biopharma — Surv Biopharma develops a drug discovery platform that facilitates research and development of veterinary drugs and pharmaceutical products.
• Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.
• Restore Vision — Restore Vision is a startup based in Japan aiming to develop a visual restoration gene therapy.

Portfolio highlights

• Ayumo — Ayumo is a research and development company that provides deep learning services with medical insights and AI technology.
• QunaSys — Quantum physics is a relatively new field built since the beginning of the 20th century, but we have used MRI (nuclear magnetic resonance equipment) and lasers used for close examinations in hospitals, and semiconductors mounted on computers. Supports the technology that supports the daily life of people.QunaSys was established to bring out thequantum physics that has been active behind the scenes to the front stage, and to make use of quantum properties to realize technologies that could not be achieved with existing technologies.
• Celaid Therapeutics — Celaid Therapeutics specializes in manufacturing and sales of regenerative medicine products utilizing human hematopoietic stem cells.

Portfolio highlights

• Caguuu — Caguuu offers high-quality designer furniture at affordable prices, through e-commerce, eliminating middlemen and store operating costs.
• QREATION — QREATION is a digital intellectual property studio specializing in producing a wide range of popular content that originates primarily from social media platforms. The company focuses on creating high-quality short-form entertainment, including short dramas, comedy sketches, and variety shows.
• ARCS — ARCS specializes in developing assisted reproductive medical devices using robotics and artificial intelligence technology.

Portfolio highlights

• Logiless — Logiless is a cloud type all-in-one software dedicated to net shop. Since both orders and stocks can be managed together in a logical manner, efficiency of operations can be realized at low cost.
• ARCS — ARCS specializes in developing assisted reproductive medical devices using robotics and artificial intelligence technology.
• OpenHeart — OpenHeart is a provider of the tactile 3D platform.

Portfolio highlights

• ALGO ARTIS — ALGO ARTIS is a software company that offers optimization in plant operations, tanking, ship allocation plan, and logistics.
• SUN METALON — SUN METALON aims to create a world where metal products can be produced from local ores. The company was founded in 2021 and is headquartered in Redondo Beach, California.
• BUGWORKS Research — Bugworks, a clinical stage biopharmaceutical company Harnessing the power of science to develop affordable, accessible, novel therapies against infectious disea

Portfolio highlights

• Ashirase — Ashirase is a developer of a walking navigation system for the visually challenged. The company assists visually impaired people in walking independently. This also allows the user to have more attention to spare for audible warnings in their environment. It includes voice input and guidance via a smartphone app. A vibration interface is attachedto their shoes.
• Ken Robotec — Ken Robotec is a construction company that provides labor-saving solutions.
• MaterialGate — MaterialGate focuses on single-molecule dielectrics, developing technologies for devices with better electronic characteristics.

Portfolio highlights

• Reject — Reject is an esports firm that focuses on management of its team REJECT, players, apparel business, and event management services.
• Linqmed — Linqmed is a pharmaceutical company that specializes in the research and development of radiopharmaceuticals for cancer treatment.
• Japan Culture and Technology — Japan Culture and Technology assists artists and craftspeople in expanding their activities by providing IT support.

Portfolio highlights

• InsightX — InsightX is a technology platform focused on empowering businesses by simplifying complex processes and enabling smarter, more personalized user experiences.
• ElevationSpace — ElevationSpace offers high quality & well equipped workspaces giving tenants a nurturing environment .
• Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Portfolio highlights

• Tear Exo — Tear Exo is a biotechnology research company that produces and sells liquid biopsy using materials for molecular recognition.
• TelaAxon — TelaAxon develops artificial intelligence technology for sustainable operations, enhancing human-AI coexistence, safety, and wellness.
• Akari Hosho — Akari Hosho provides a group of trusted professionals, including lawyers and judicial scriveners. Akari Hosho provides a guarantee service.

Portfolio highlights

• Recho — Recho’s voice AI solutions must offer some unique features. Recho has a mission to "create the future of communication" and provides the VoiceAI platform and its application, Voice Agent.
• Pliant — Pliant makes the latest generation of corporate credit cards that adapt perfectly to business processes and needs.
• Captain Fresh — Captain Fresh is a freshwater fish and seafood supply chain platform. Captain Fresh is a B2B marketplace leveraging technology to deliver the fastest harvest-to-retail in the industry. The company focuses on aggregating the fragmented retail demand across the country and linking them to the small fishermen and farmers throughout the Indian coast.The company was founded in 2019 and is based in Bengaluru, India.

Portfolio highlights

• Eitoss — Eitoss is a technology company which has developed and provided the proposal improvement cloud "Cayzen".
• Recerqa — Recerqa is a supply chain management SaaS that utilizes advanced development technology and AI to improve the purchasing, inventory, and sales management experiences.
• Finovo — Finovo specializes in the research, development, operation, and maintenance of cutting-edge accounting and financial software solutions.

Portfolio highlights

• Anyplace — Find furnished accommodations to rent for a month or longer. Choose apartments catered for remote work with an equipped home office and high-speed internet.
• Social Bread — Marketplace Influencer untuk UMKM Indonesia
• Appify Technologies — Appify Technologies, Inc.

Portfolio highlights

• Flosfia — FLOSFIA is a spin-off from a research of Kyoto University, specializing in film-formation by mist chemical vapor deposition (CVD). Making use of physical properties of gallium oxide (Ga2O3), FLOSFIA has devoted to development of low-loss power devices.
• VLP Therapeutics — VLP Therapeutics, LLC (VLP) was established in 2012 by seasoned biopharmaceutical veterans with mission to develop innovative medical treatment which transforms traditional vaccine and targeted antibody therapies to address global unmet medical needs. Its vision is to combat the 21st century global public health problems through revolutionary nextgeneration i-αVLP (inserted alpha VLP) Technology. The company is headquartered in Gaithersburg, Maryland
• XFOREST Therapeutics — xFOREST Therapeutics develops a drug discovery platform that targets RNA structures.

Portfolio highlights

• Letara — Letara operates a space technology platform with the intention to serve a logistics network covering the solar system. The company produces hybrid propulsion engines for small spacecraft, promoting groundbreaking advances in space propulsion with high thrust, safe, and inexpensive propulsion system technology.
• Akari Hosho — Akari Hosho provides a group of trusted professionals, including lawyers and judicial scriveners. Akari Hosho provides a guarantee service.
• Black Cat Carnival — Black Cat Carnival Inc. is a communication service development company.

Portfolio highlights

• Near Intelligence — Near, the world’s largest source of intelligence on People, Places, and Products is the global leader in Data Intelligence empowering organizations of all sizes to make smart, strategic decisions delivering optimal business performance. We unite Marketers and Operational data leaders by providing the most accurate, reliable source of data thatdelivers actionable insights on People, Places, and Products in both the physical and digital space.Near is backed by leading investors including Sequoia Capital, JP Morgan Private Equity Group, Cisco Investments and Telstra Ventures. Visit www.near.com to find out more.
• Otetsutabi — Otetsutabi is a regional revitalization platform that offers the opportunity for participants to help at accommodations and breweries in rural areas that struggle with seasonal labor shortages. The locals offer transportation expenses and places to stay in return, so participants can travel to the areas with ease.
• Supercritical — We partner with industry to move and think beyond fossil fuels with innovative clean technology solutions.

Portfolio highlights

• 3DC — 3DC develops and manufactures a new carbon material, graphene meso sponge (GMS), for electrodes in next-generation batteries, capacitors, fuel cells and other energy storage and generation devices.
• THE PHAGE — The phage is a medical device company that focuses on developing AI technology to predict postprandial blood glucose levels.
• Mira Robotics — Mira Robotics is a software based company provide services that can robots in various fields.

Portfolio highlights

• Kinish — Kinish is a company leading a revolution in dairy products. To achieve environmentally friendly and delicious dairy products, we are developing a special rice variety that produces milk proteins.
• Kwahuu Ocean — Kwahuu Ocean develops sustainable squid farming systems.
• Spine Chronicle — Spine chronicle is a medical device manufacturing firm that specializes in developing orthopedic medical equipment.

Portfolio highlights

• OptQC — OptQC commercializes cutting-edge optical quantum computing technologies developed by the Furusawa-Endo Laboratory. Because optical quantum computers are more scalable than superconducting and other quantum computing implementations, OptQC's optical quantum computers should reach this scale. They also have benefits like faster processing andreduced power consumption, which makes optical quantum computers a possible long-term pinnacle of quantum technology.
• Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
• Flosfia — FLOSFIA is a spin-off from a research of Kyoto University, specializing in film-formation by mist chemical vapor deposition (CVD). Making use of physical properties of gallium oxide (Ga2O3), FLOSFIA has devoted to development of low-loss power devices.

Portfolio highlights

• NovAccel — NovAccel operates as a deep tech company, ensure a stable supply of medical radioisotopes.
• Trustart — Trustart engages in real estate research business and real estate big data provision. The company offers real estate big data and big data subscriptions.
• Tech Doctor — Tech Doctor is a health monitoring service which provides analysis and insights for self care reducing the need for health care workers.

Portfolio highlights

• Amptalk — Amptalk is a software development firm specializing in operating automatic transcription and analysis of online business negotiations.
• Grafenary — Graphenary creates unique graphene optical devices using graphene materials with a variety of remarkable features.
• NanoFrontier — NanoFrontier continues to market technologies that are widely available and incredibly inexpensive.

Portfolio highlights

• Banzai — Leverage Banzai's event solutions to transform your bored registrants into paying customers. Learn more about Reach and Demio today.
• Siftery — Siftery is a database of sorts where companies list their software stacks. Siftery compares companies with similar stacks and looks for differences to make some recommendations.
• SecureNavi — SecureNavi offers automation tools for the information security management system. It reduces conventional analogue operations using excel and word. For inquiries, telephone numbers and physical addresses are available on their website.

Portfolio highlights

• HCMJ — HCMJ specializes in software development in the medical industry.
• Epigno — Epigno provides hospital management systems for medical institutions.
• Rehab — Rehab for Japan is developing a special rehabilitation SaaS for day service .

Portfolio highlights

• Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
• RoboTruck — RoboTruck develops autonomous driving technologies for huge trucks, as well as practical applications.
• Leading Mark — Leading Mark, a rising human resources startup in Japan. Leading Mark is branching out into mid-career and international hiring. It currently has a one-man team in China working to bring the top Japanese-speaking Chinese students to domestic companies. He also touts his startup’s focus on the average job seeker. “We want to make sure that the usersget the info that he or she needs the most,” he says. Large scale, legacy players can sometimes prioritize the needs of the hiring company, and their commission, over the needs of applicants themselves. This leads to frustration and short-circuited careers.

Portfolio highlights

• ThinkCyte — ThinkCyte provides single-cell analysis for research, diagnostics, and therapeutics with an integrated multidisciplinary approach.
• NodeX — We build open-source embedded software and cloud tools to help developers build secure IoT products, simply. By leveraging decentralized identity and h/w root of trust technology, IoT security platform "UNiD" enables developers to automate device management and easily build secure data pipeline between every devices and the cloud.
• CMerTV — CMer TV is a platform that connects advertisers with newspapers, magazines, and specialized media by video

Portfolio highlights

• JOYCLE — JOYCLE is a waste management company that specializes in trash recycling, disposal, and environmental consulting services.
• Autify — AI software testing company aimed at solving the challenges associated with automation testing. We are passionate about making software testing faster and easier, empowering companies to release faster and keep their applications stable.
• Rara — Rara offers carbon-free and organic mushroom culture production equipment.

Portfolio highlights

• Gyodi —
• Pathzero — Pathzero's carbon management platform enables any business to start disclosing corporate carbon emissions and the actions being taken to address them.
• Unseen — Unseen is a market intelligence platform for commercial real estate.

Portfolio highlights

• Emole — Emole is a platform that connects content creators with viewers through short drama content, offering a variety of engaging stories.
• Loglass — Loglass offers corporate intelligence to enhance business management.
• GenerativeX — GenerativeX provides AI app development, consulting, and generative model development.

Portfolio highlights

• Mechano Cross — Mechano Cross is a mechanical company that offers mechanochemical organic synthesis technology for solution reactions.
• Rendez-Vous — RENDEZ-VOUS offers a co-ownership option for vintage cars.
• RICOS — RICOS is a tech company that optimizes manufacturing processes using AI, simulation, and high-performance computing technologies.

Portfolio highlights

• Ashirase — Ashirase is a developer of a walking navigation system for the visually challenged. The company assists visually impaired people in walking independently. This also allows the user to have more attention to spare for audible warnings in their environment. It includes voice input and guidance via a smartphone app. A vibration interface is attachedto their shoes.
• Godot — Godot's mission is to “inspire personal and societal growth through human augmentation”. As part of this mission, we are developing a Behavior Intelligence Platform (BIP) that helps enterprises improve UX, CX, and EX by visualizing human behavior principles and making it easy for anyone to implement insights from behavioral science. Thisplatform leverages evidence from behavioral sciences and advanced AI technologies. Our technology has already proven successful in health insurance industries, resulting in significant improvements in customer retention and satisfaction. Our team comprises experts in AI, behavioral science, and industry-specific applications, bringing a wealth of experience and knowledge to our solutions. Together, we are committed to creating a society where everyone can enjoy a healthy and fulfilling life, true to themselves, with the support of Godot's innovative technologies.
• Pickleball One — Pickleball one is to become an enabler of the pickleball industry , spreading the joy of "Fun as one" to the world.

Portfolio highlights

• Sazo — Sazo specializes in constructing a global e-commerce and logistics network with AI.
• Pragtech — Pragtech develops and operates parking lot service software that helps to eliminate payment congestion and reduce operating costs.
• Shinsekai Technologies — SHINSEKAI Technologies focuses on supporting companies, enabling them to advance their services to Web3 and NFT technologies.

Portfolio highlights

• STRACT — STRACT is a web platform that provides online platform, dating app, knowledge sharing cloud platform, and casual entertainment services.
• SmartHR — SmartHR helps Japanese companies bring HR activities into the digital age. SmartHR makes HR simpler for Japanese companies by replacing spreadsheets and paperwork with a user-friendly online solution. When SmartHR was founded in Japan in 2013, on-boarding and off-boarding employees was a tedious process, especially since employers had to apply forsocial insurance and healthcare on behalf of employees using a process that had not yet been digitized. Today, SmartHR delivers massive savings for companies across diverse segments from high tech to retail by decreasing the time to complete HR processes like employment contracts down from one month to just 1-2 days. After catering to its initial offering to startups and small businesses, SmartHR is expanding its business to serve more enterprise customers.
• PartnerSuccess — PartnerSuccess develops and provides SaaS tools that automate the collaboration between manufacturers and distributors.

Portfolio highlights

• Pale Blue — Water propulsion systems for sustainable space development
• SPACER — SPACER is a 24-hour handover IoT locker that can open and close doors with a smartphone.
• Gaudi Clinical — Gaudi Clinical is a health care firm that engages in regenerative medicine outsourcing and cell processing contract establishments.

Portfolio highlights

• LIFESCAPES — LIFESCAPES is a research and manufacturer of brain-computer interface equipment.
• Metcela — Cells hold endless possibilities. Through science, we will unlock these potentials and harness them to improve the lives of patients worldwide.
• Hirosaki Lifescience Innovation — Hirosaki Lifescience Innovation is engaged in the development, manufacture, and sale of regenerative medicine products.

Portfolio highlights

• SOUNDRAW — Your personal AI music generator.
• Inter Holding — Inter delivers solutions for global difficulties using vacuum technology, which uses a particular check valve to maintain a 99.5% vacuum rate.
• Better Place — Better place vision is to create a world in which kind people can continue to be kind, as well as a society in which people can work in their own way without worrying about money.

Portfolio highlights

• MOVeLOT — MOVeLOT is an AI company that provides skeletal platform and robot planning, development, and production services.
• Kisui Tech — Kisui Tech is an agricultural AI robotics company that help farmers for farming.
• LYMPHOGENiX — LYMPHOGENiX is the pioneer company for lymphatic vessels regeneration. Our proprietary technology revitalizes the function of lymphatic vessels, making us experts in treating various health conditions. Our treatment is also great for skin-aging, obesity, Alzheimer's diseases and infertility. We believe in helping our clients improve their vitality and energy, one treatment at a time.

Portfolio highlights

• Sagri — Sagri is developing agriculture software for experienced farmers.
• Good News — Good News is a staffing agency that provides recruitment, public relations, and human resource management services.
• Rehabilitation 3.0 — Rehabilitation 3.0 focuses on a preventive medical system that provides AI assessment and tracking on health, exercise, mood, and wellness.

Portfolio highlights

• Airato — Airato specializes in the development of radiation therapy using artificial intelligence technology.
• Knowhere — Knowhere is a company that applies high-performance AI to sports.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• G-ant — G-ant runs the MITACLE BLOCK service, transforming 2D illustrations into custom 3D block figures using voxel technology.
• MoonJapan — MoonJapan is an educational impact startup that offers a variety of programs and thorough assistance.
• Prefab — Prefab offers cutting-edge AI SaaS solutions tailored for the construction industry, enhancing efficiency, safety, and decision-making through data-driven insights.

Portfolio highlights

• Hacobu — Hacobu offers an integrated solution "MOVO (MOVO)" centering on the operation management system utilizing in-vehicle terminals. Connect with carriers and shipping companies sending luggage using an easy-to-use online mechanism. To provide tools to support the management of the shipping company. Through these, it becomes a platform toaccumulate distribution data of various companies, aiming at overall optimization of physical distribution system. That is, "to optimize carrying". That is Hacobu 's mission.
• TeraWatt Technology — Electrifying all for the sustainable future
• Metagen Therapeutics — Metagen Therapeutics is a Drug discovery and medical business company which utilizes microbiome science.

Portfolio highlights

• Ripcord — Ripcord is a robotics company that combines hardware and software robotics via an integrated SaaS offering. Its focus is on smart robotics digitization, smart content management with AI, and helping enable RPA and business processes.Ripcord is based in Hayward, California, and is backed by leading investors Kleiner Perkins Caufield & Byers,Google Ventures, Lux Ventures, Legend Star, and Apple Co-Founder Steve Wozniak.
• 24M Technologies — 24M Technologies develops energy storage systems for grid and transportation applications. 24M Technologies, Inc. builds energy storage systems for grid and transportation applications. The company was founded in 2010 and is based in Cambridge, Massachusetts.
• Tome Biosciences — Tome Biosciences is a biotechnology company that develops programmable gene insertion technology. Using CRISPR, its technologies allow them to insert any genetic sequence of any size at any location into any genome.

Portfolio highlights

• RevolKa — RevolKa manufactures bio-products pharmaceuticals intended to serve the healthcare sector.
• Alpha Fusion — Alpha Fusion Inc. is a clinical-stage startup committed to transforming cancer treatment through the design and development of powerful and precise radiopharmaceuticals.
• Neros Technologies — Neros is vertically integrating production of unmanned defense systems in the United States, securing the autonomous supply chain. Are you with us?

Portfolio highlights

• Airato — Airato specializes in the development of radiation therapy using artificial intelligence technology.
• Robofull — Robofull is a manufacturing firm that specializes in the design and sale of automation equipment for factories to solve the labor shortage.
• Illumi Medical — Illumi Medical is a manufacturing company that produces medical equipment and devices for the healthcare sector.

Portfolio highlights

• AGRIST — AGRIST Co., Ltd. is a venture company that solves agricultural problems with technology. An automatic harvesting robot solves the problem of a shortage of farmers who are aging and harvesting agricultural products.
• Digireha — Digireha is an IT company that provides a tool for rehabilitation by combining digital art and sensors.
• Medmain — To create a world where medical services can be accessed with technology anywhere,anytime-As a supporting partner to medical practitioners throughout the world, Medmain develops and operates PidPort, an analytical system for pathological image diagnosis that makes use of Deep Learning, as well as Medteria, a specialized cloud-based service for medical students.