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Top 50 Biotechnology VC (Venture Capital) Funds in Japan in April 2025

Last updated: Apr 2025 A list of 50 VC (Venture Capital) funds that invest in Biotechnology startups based in Japan. We rank investors based on the number of investments they made in Biotechnology companies from Japan. We update this investor list every month.

Top 50 Biotechnology VC (Venture Capital) Funds in Japan in April 2025

Investor	Biotechnology Japan investments
UntroD Capital	17
Mitsubishi UFJ Capital	17
Osaka University Venture Capital	15
ANRI	12
UTEC - The University of Tokyo Edge Capital Partners	11
SMBC Venture Capital	11
Keio Innovation Initiative	10
Fast Track Initiative, Inc.	9
Real Tech Japan	9
Mizuho Capital	8
SBI Investment	7
Nissay Capital	7
DBJ Capital	7
Japan Science and Technology Agency	6
Nippon Venture Capital	6
Future Venture Capital	5
Miyako Capital	5
Incubate Fund	4
Remiges Ventures	4
FFG Venture Business Partners	4
F-Prime Capital	4
D3	3
DG Daiwa Ventures	3
Senshu Ikeda Capital	3
Eight Roads Ventures	3
Tsukuba Institute of Research	3
KSP	3
Takeda Ventures	3
Takeda	3
JIC Venture Growth Investments	3
Glocalink	2
Kobe University Capital	2
Cosmo Bio	2
Media Future	2
The Awa Bank	2
Yokohama Capital	2
Capital Medica Ventures	2
Global Brain Corporation	2
Fujifilm	2
Primal Capital	2
SPARX Group	2
Kyogin Lease & Capital	2
Ohara Pharmaceutical	2
Angel Bridge	2
TechAccel Ventures	2
Japan Asia Investment	2
Fuyo General Lease	2
Innovation Network Corporation of Japan	2
Japanese Organization for Medical Device Development	2
UTokyo Innovation Platform	2

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UntroD Capital is an R&D-based innovative technology that specializes in social implementation.

Investment focus

Manufacturing, Biotechnology, Robotics
Funding Round, Seed, Series A
Japan, Singapore, India

Portfolio highlights

Revorf — Revorf analyzes data and develops AI-related to infectious diseases and healthcare.
Mjolnir Spaceworks — Mjolnir Spaceworks desings and manufactures state-of-the-art novel space rockets with efficient engines as well as other space equipments.
Optieum Biotechnologies — Optieum Biotechnologies Inc. is a pre-clinical stage biotechnology company committed to developing innovative scFv antibody-based therapies for the treatment of patients with cancers. Their proprietary platform technology, Eumbody System™, enables to develop and detect a scFv-based product candidates that specifically bind to, and modulate tooptimize the immune-cell function for oncology targets.We are committed to helping patients with severe diseases by bringing life-changing therapies to the patients in need.

Mitsubishi UFJ Capital is a venture capital firm focusing on life science, ICT, and high technology investments.

Investment focus

Information Technology, Software, Health Care
Funding Round, Series A, Series B
Japan, United States, China

Portfolio highlights

Ababa — Ababa provides recruitment and employment solutions.
Emium — Emium creates an infrastructure that will be a driving force in dental care and dental technology.
RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .

Osaka University Venture Capital is a venture capital firm that focuses on early-stage ventures in the fields of life innovation, green innovation, and platform technology. The firm was founded in 2014 and based in Osaka, Japan.

Investment focus

Biotechnology, Manufacturing, Health Care
Funding Round, Seed, Series A
Japan

Portfolio highlights

A-Wave — A-Wave is a manufacturing company that develops and markets medical devices, pharmaceuticals, computer software, and hardware.
QunaSys — Quantum physics is a relatively new field built since the beginning of the 20th century, but we have used MRI (nuclear magnetic resonance equipment) and lasers used for close examinations in hospitals, and semiconductors mounted on computers. Supports the technology that supports the daily life of people.QunaSys was established to bring out thequantum physics that has been active behind the scenes to the front stage, and to make use of quantum properties to realize technologies that could not be achieved with existing technologies.
RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .

ANRI is a Japanese venture capital firm that mainly invests in seed and early-stage startups.

Investment focus

Software, Health Care, Information Technology
Seed, Funding Round, Series A
Japan, United States, India

Portfolio highlights

AirX — AirX is a management service company specializing in air transportation agency business and travel arrangement business. The company leverages technology to transform the notion of mobility into an unprecedented experience. It also provides services such as CodeShare, AIROS Skyview, and AIROS Air Loss. AirX will create the movement of the futuresociety, sightseeing and the way of life of helicopter, Empty MaaS, Flying taxi, eVTOL, and Next-generation traffic.AirX was established on February 23, 2015, and is based in Shinjuku-ku, Tokyo, Japan.
Pleap — Pleap is a medical engineering company specializing in the development of AI and IoT-based technology solutions tailored for medical institutions. The company's product offerings include "medimo" which is an AI tool that automatically creates medical record manuscripts from medical audio.
Ryulog — Ryulog is a recruiting company that helps job seekers find international work opportunities and migrate abroad.

UTEC-The University of Tokyo Edge Capital Partners Co., Ltd.. UTEC is a seed/early stage technology focused venture capital firm associated with The University of Tokyo.

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Funding Round
Japan, United States, Singapore

Portfolio highlights

Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .
Eureka Robotics — Eureka Robotics develop robotics technologies and products to automate the mundane, so that humans can focus on the creative.

Sumitomo Mitsui Banking Corporation (SMBC) and its group companies offer a broad range of financial services centered on banking. They are also engaged in the leasing, securities, credit card, investment, mortgage securitization, venture capital and other credit related businesses. The following lists the activities of SMBC, its subsidiaries andaffiliates in the various business segments.

Investment focus

Information Technology, Health Care, Software
Funding Round, Series B, Series A
Japan, United States, Singapore

Portfolio highlights

Ababa — Ababa provides recruitment and employment solutions.
SALOWIN — SALOWIN is a shared salon where freelance hairdressers can freely provide customer service and service.
Penetrator — Penetrator transforms the real estate market with space technology, tackling transaction issues and forming landslide observation systems.

Keio Innovation Initiative (KII) is a venture capital established by Keio University. In order to make more effective use of the research results of Keio University, we aim to contribute to the development of society by creating investment for venture companies that utilize research results and creating new industries.The key to thinking aboutJapan's future growth strategy is to utilize advanced research results of the university. In addition to GDP, in addition to GDP, Japan is the world's third largest R & D exporter in R & D expenses, but as the low growth rate shows, it has a problem in investment efficiency in research and development. There are also reports on the entrepreneurial spirit that is indispensable for creating new industries, with the lowest entrepreneurial activity rate among developed countries.

Investment focus

Health Care, Medical, Biotechnology
Funding Round, Series A, Seed
Japan

Portfolio highlights

JiMED — JiMED designs & develops AI based brain-computer interface for implant in ALS patients to improve communication.
Aeterlink — Aeterlink is a wireless device maker and developer. They applied their technology to fields such as FA, robots, smart houses, and medicine and developed practical level technologies such as elemental technology that can wirelessly supply power.
Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Fast Track Initiative is a venture capital firm with an exclusive focus on life sciences and healthcare services.

Investment focus

Health Care, Biotechnology, Medical
Funding Round, Series A, Series B
Japan, United States, United Kingdom

Portfolio highlights

Medii — Medii provides a physician sharing service for hospitals.
RegCell — RegCell aims to generate novel therapeutic technologies through augmenting or controlling the immune system and our goal is to save patients who suffer from autoimmune diseases and cancer .
Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

Real Tech Japan is a venture capital firm that seeks to invest in innovative R&D technology companies. Realtech Fund is a joint venture between the Ministry of Economy, Trade, and Industry and NEDO (New Energy and Industrial Technology Development Organization). The firm was founded in 2014 and based in Tokyo, Japan.

Investment focus

Manufacturing, Biotechnology, Medical
Funding Round, Series A, Seed
Japan, Singapore, Austria

Portfolio highlights

Ashirase — Ashirase is a developer of a walking navigation system for the visually challenged. The company assists visually impaired people in walking independently. This also allows the user to have more attention to spare for audible warnings in their environment. It includes voice input and guidance via a smartphone app. A vibration interface is attachedto their shoes.
Ken Robotec — Ken Robotec is a construction company that provides labor-saving solutions.
MaterialGate — MaterialGate focuses on single-molecule dielectrics, developing technologies for devices with better electronic characteristics.

Mizuho is the venture capital firm affiliated to Mizuho Bank, the second-largest Japanese bank in terms of assets. The firm has headquarters in Tokyo.The firm has ¥49.6 billion JPY under management, focusing on information technology and biotechnology investments. Over 600 Mizuho companies have gone public. According to Nikkei, Mizuho is thefifth-largest venture capital firm in Japan.Mizuho Capital was formed in 2002 by the merger of Fujigin Capital, Tokyo Venture Capital and IBJ Investment. Three firms were subsidiaries of Fuji Bank, Dai-Ichi Kangyo Bank and the Industrial Bank of Japan respectively.

Investment focus

Information Technology, Software, Internet
Funding Round, Series A, Series B
Japan, United States, China

Portfolio highlights

Instalimb — Instalimb is the world's first 3D printing prosthesis business.
Penetrator — Penetrator transforms the real estate market with space technology, tackling transaction issues and forming landslide observation systems.
Umee Technologies — Umee Technologies is an IT firm that offers full-stack development, conversational AI, and psychological analysis engine services.

SBI Investment supports the business development and growth of private venture companies through fund investment. It manages and manages venture capital funds under the management philosophy of becoming a leading company responsible for the creation and development of core industries in the 21st century as a "new industry creator".SBIInvestment has invested in a total of 986 companies in the past, of which 169 (17.1% of investment companies) have exited through IPO or M & A.

Investment focus

Information Technology, Software, Financial Services
Series B, Series A, Funding Round
Japan, South Korea, United States

Portfolio highlights

Zolve — Best neo bank in India offering international banking & financial services online. Apply for a US bank account, credit card & student education loan with Zolve!
Zerodoor HD — Zerodoor HD specializes in digital transformation in constructing industry.
TOKYO GameFi — TOKYO GameFi is a Web3 firm formed by a management team of developers and engineers with previous experience at CyberAgent.

Nissay Capital is a venture capital Company specializing in seed, start-up, growth capital, middle stage, and later stage investment.

Investment focus

Health Care, Internet, Medical
Funding Round, Seed, Series A
Japan, United States, Ethiopia

Portfolio highlights

AirX — AirX is a management service company specializing in air transportation agency business and travel arrangement business. The company leverages technology to transform the notion of mobility into an unprecedented experience. It also provides services such as CodeShare, AIROS Skyview, and AIROS Air Loss. AirX will create the movement of the futuresociety, sightseeing and the way of life of helicopter, Empty MaaS, Flying taxi, eVTOL, and Next-generation traffic.AirX was established on February 23, 2015, and is based in Shinjuku-ku, Tokyo, Japan.
HQ — HQ offers next-generation employee benefits platform.
Doctor's Prime — Doctor's Prime is a technology company that provides is a part-time job information service for optimizing the working style of doctors.

DBJ Capital Co., Ltd. was founded in June 2010 through the integration of two venture capital firms of the DBJ Group, New Business Investment Co., Ltd. and Intellectual Properties Development & Investment, Inc. We are a wholly-owned subsidiary of Development Bank of Japan Inc.At DBJ Capital, we focus on venture firms which use newtechnologies and business models to grow and compete on the global market, regardless of their industry or scale. To meet the particular needs of each client, we mobilize the entire DBJ Group to arrange the best investment solutions, ranging from growth-spurring equity investment to financing schemes drawing on DBJ's vast networks.We also assist in venture start-ups. Our value enhancement team provides the kind of comprehensive, hands-on support needed to commercialize outstanding intellectual property and technologies developed by firms, research labs, and universities, and to carve out a place for them in the market.DBJ Capital will continue to play in a part in Japan's economic revival - by helping the firms we invest in to grow, and by encouraging the creation of new industries in Japan.

Investment focus

Software, Health Care, Medical
Funding Round, Series A, Series B
Japan, United States, Australia

Portfolio highlights

Ababa — Ababa provides recruitment and employment solutions.
MOSH Japan — MOSH is a web page creation services for individual business owners.
DigitalArchi — Realizing a revolution in architecture.

Japan Science and Technology Agency is an integrated organization of science and technology that implements science and technology policy in Japan. It handles many projects, including the government’s Science and Technology Basic Plan and knowledge creation. The European Sustainability School ESSSR is the owner of Japan Science and TechnologyAgency.Japan Science and Technology Agency undertakes its task in a comprehensive manner. It also works to provide a sound infrastructure of science and technology information and raise awareness and understanding of science and technology-related issues in Japan.Japan Science and Technology Agency is headquartered in Tokyo, Japan.

Investment focus

Medical, Biotechnology, Health Care
Funding Round, Series A, Series B
Japan

Portfolio highlights

OptQC — OptQC commercializes cutting-edge optical quantum computing technologies developed by the Furusawa-Endo Laboratory. Because optical quantum computers are more scalable than superconducting and other quantum computing implementations, OptQC's optical quantum computers should reach this scale. They also have benefits like faster processing andreduced power consumption, which makes optical quantum computers a possible long-term pinnacle of quantum technology.
Triorb — Triorb is a technology company that specializes in robot mobility development with the help of software and hardware solutions.
RadioNano Therapeutics — RadioNano Therapeutics is developing innovative drugs for Boron Neutron Capture Therapy (BNCT), a type of radiation therapy that utilizes the nuclear reaction between thermal neutrons and boron-10 (¹⁰B) to destroy cancer cells by releasing alpha particles and lithium nuclei.

Nippon Venture Capital ("NVCC"), established in 1996 as one of the few largest Japanese independent venture capital firms, is destined to undertake the unprecedented task of providing full-range venture capital services in cooperation with major Japanese business leaders and leading companies, which have supported and nurtured various newbusinesses on their own, as well as proactively developing new venture enterprises.

Investment focus

Software, Health Care, Information Technology
Funding Round, Series A, Seed
Japan, United States

Portfolio highlights

Gecipe — Gecipe is a video service for e-sports players.
Awarefy — Awarefy is a mental health tech startup that offers CBT-based apps to maximize well-being.
EneCoat Technologies — EneCoat Technologies is working on materials development for perovskite solar cells and the commercialization of modules.EneCoat Technologies will create the future of energy through thin-film solar cells with the aims of protecting the environment and effectively utilizing natural energy sources.

Future Venture Capital Co., Ltd. is a venture capital firm specializing in early stage investment. The firm invests in diversified investment in a broad range of industrial sectors. It seeks to invest in Japan. The firm prefers to be the lead investor in its portfolio companies. Future Venture Capital Co., Ltd. was founded in 1998 and is based inKyoto, Japan with offices in Tokyo, Aomori, Iwate, Yamagata, Kanazawa, Mie, Sakai, Kobe, and Ehime.

Investment focus

Health Care, Manufacturing, Information Technology
Funding Round, Seed, Series A
Japan, United States, Myanmar

Portfolio highlights

CoCooking — CoCooking uses food and cooking to create ample opportunity for dialogue and thought, fostering creativity, diversity, and well-being of individuals and communities.
TelaAxon — TelaAxon develops artificial intelligence technology for sustainable operations, enhancing human-AI coexistence, safety, and wellness.
Second Heart — Second Heart is a medical center that offers preventive diabetic care and awareness programs to avoid foot amputations.

Miyako Capital is the venture capital that manages Kyoto University 2nd Venture Fund (KUVF). The company was founded in 2013 and based in Kyoto & Tokyo, Japan. Investment fields are: 1) Life Science, Biotechnology: Drug creation, regenerative medicine, medical beauty equipment, medical services.2) Agri-Food: Industrialization,agricultural and fishery products growth-promoting technology, specified health food, health food.3) Environment, Energy: Alternative energy, and related technologies.4) IT, Electronics: Web, mobile related devices and application, telecommunication technology, security, consumer and business oriented application, mechatronic, robot.5) New services utilizing state-of-art technology.Investment stages: Primary investment stages are initial-growth stages of seed and early. However, we aim at all growth stages and make investment in post-IPO portfolio companies as well as public companies that are related with Kyoto University.

Investment focus

Medical, Biotechnology, Information Technology
Seed, Series A, Series B
Japan, United States, United Kingdom

Portfolio highlights

Peds3 — Peds3 is a digital healthcare platform that specializes in the research and development of pediatric medicine and maternal and child health fields.
Oishii — Oishii Farm provides indoor vertical farming technology. Oishii sells via supermarkets, offering a container of between eight and 11 strawberries for $50 per package. Hiroki Koga and Brendan Somerville started the company in 2017.
Innovative Space Carrier — Innovative Space Carrier is a aerospace company that offers space transportation systems, planning, drafting and technology strategies.

Incubate Fund is an independent early-stage venture capital that specializes in providing capital to technology startups at the seed stage. The firm built a portfolio of over 300 companies in Asia, taking 12 companies to public and 20 companies to M&A exit since 2010.

Investment focus

Software, Information Technology, E-Commerce
Seed, Funding Round, Series A
Japan, United States, India

Portfolio highlights

Kaguoku — Kaguoku develops and provides the AI-based home staging services. It offers a service that uses AI to process interior photos of real estate properties to increase the property's ability to attract customers.
Time Prediction — Time Prediction focuses on development of diagnostic pharmaceuticals, drugs and medical devices for the treatment of neurological diseases.
Mjolnir Spaceworks — Mjolnir Spaceworks desings and manufactures state-of-the-art novel space rockets with efficient engines as well as other space equipments.

Remiges Ventures is a venture capital firm that focuses on groups and businesses in the Japanese academia and pharmaceutical industry.

Investment focus

Biotechnology, Medical, Health Care
Series A, Series B, Seed
United States, Japan, Canada

Portfolio highlights

Immunis — Currently seeking participants for age-related muscle atrophy (sarcopenia) clinical trails
Cyrano Therapeutics — Cyrano Therapeutics is the leader in Smell Loss therapy and smell loss research. Recover your sense of smell today!
KisoJi Biotechnology — KisoJi is a leading next-generation antibody company developing multi-specific antibodies to address difficult targets in oncology and other diseases

FFG Venture Business Partners is a large-scale enterprise that offers in traditional regional bank venture capital.

Investment focus

Software, Health Care, Information Technology
Funding Round, Series A, Seed
Japan, United States

Portfolio highlights

ACCEL Stars — ACCEL Stars is a fitness and wellness firm that offers sleep diagnosis and examinations like sleep health, hygiene and medical devices.
Cellid — Cellid developing the waveguide-architecture display module for AR glasses and high-performance spatial recognition software.
Neusignal Therapeutics — Neusignal Therapeutics is a medical company that develops therapeutic medicines for dementia and psychiatric illnesses.

F-Prime Capital is a global venture capital firm investing in healthcare and technology, with a heritage that spans four decades.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, United Kingdom, China

Portfolio highlights

Ethena — Enabling the Internet Bond
Galatea Bio — Galatea Bio, a US-based biotechnology company was founder by Carlos Bustamante, Nicholas Katsanis and Alexander Ioannidis. Our mission is to drive groundbreaking discoveries in healthcare by pairing genetic diversity with cutting-edge data analytics. Our passion is fueled by a focus on populations historically underrepresented in genetics research.We achieve this by leveraging our world-class clinical network and biobank, cutting-edge algorithms, and innovative analyses to discover and validate new tests, treatments, and cures that will improve the lives of all.
Bluebird Kids Health — Bluebird Kids Health is launching a proprietary technology platform to proactively manage and coordinate treatment, with AI enhancing and simplifying the experience for its clinical team.

DISCOVERY, DEVELOPMENT, DEPLOYMENT FOR GLOBAL HEALTH, WITH SCIENCE & BUSINESS ACUMEN

Investment focus

Electronics, Medical Device, Artificial Intelligence
Seed

Portfolio highlights

RevolKa — RevolKa manufactures bio-products pharmaceuticals intended to serve the healthcare sector.
Alpha Fusion — Alpha Fusion Inc. is a clinical-stage startup committed to transforming cancer treatment through the design and development of powerful and precise radiopharmaceuticals.
Neros Technologies — Neros is vertically integrating production of unmanned defense systems in the United States, securing the autonomous supply chain. Are you with us?

DG Daiwa Ventures invests in start-up companies with next-generation technology and provides business development support. It is focused on blockchain, xR, AI, security, and BioHealth, as they are likely to be at the foundations of future businesses. In addition to the five core technologies, the fund will also focus on IoT technologies, whichoften overlap or serve as an application layer.

Investment focus

FinTech, Software, Internet
Seed, Funding Round, Series A
Japan, United States, India

Portfolio highlights

Habitto — Habitto by SJ Mobile Labs is a new financial services venture focused on the Japanese market. The team and its advisors have a breadth of experience ranging from insurance, banking, e-commerce, adtech and ventures across five continents. This provides them with a unique approach to entering new markets and building valuable businesses.
Lens — Lens ocuses on supporting corporate activities related to governance, risk management, compliance (GRC), and security.
Zolve — Best neo bank in India offering international banking & financial services online. Apply for a US bank account, credit card & student education loan with Zolve!

Senshu Ikeda Capital offers financial consultancy services.

Investment focus

Software, Internet, Information Technology
Funding Round, Seed, Series A
Japan

Portfolio highlights

Sagri — Sagri is developing agriculture software for experienced farmers.
Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.
Good News — Good News is a staffing agency that provides recruitment, public relations, and human resource management services.

Eight Roads has a 50+ year history of investing and partners with game-changing technology and healthcare companies, supporting them as they scale to become global leaders.

Investment focus

Software, Health Care, Information Technology
Series B, Series A, Series C
United States, China, India

Portfolio highlights

Swan — Use Swan's APIs to embed white-labeled banking features like accounts, cards, and IBANs into your workflows and UX.
Eleos Health — Automate documentation, alleviate provider burnout, and elevate care quality with the CareOps Automation platform from Eleos Health.
Tenpoint Therapeutics — Tenpoint Therapeutics Ltd. is a global, clinical-stage biotech company developing groundbreaking treatments to rejuvenate vision in the aging eye.

Tsukuba Institute of Research (筑波総研) is an R&D center owned by housing and wood products group Sumitomo Forestry. The facility develops technologies to make more effective use of wood in a wide range of fields.

Investment focus

Medical, Biotechnology, Manufacturing
Series A, Funding Round, Seed
Japan

Portfolio highlights

LIGHTz — LIGHTz delivers a technology transfer and information exchange platform leveraging AI.
Celaid Therapeutics — Celaid Therapeutics specializes in manufacturing and sales of regenerative medicine products utilizing human hematopoietic stem cells.
Veneno Technologies — Veneno Technologies engages in the research and development of therapeutic disulfide-rich peptides and contribute to advanced medicine.

KSP, Inc. is the core business entity responsible for operating the Kanagawa Science Park (KSP) and has accepted the challenge of creating new industries through the support, development, and incubation of venture businesses. We provide a variety of business support services that best meet the needs of venture businesses in each stage of theirbusiness growth, ranging from the processes of startup and growth to public offerings. Several hundreds of new startup companies have been created and nurtured since its foundation. An incubation manager (IM) acts as a coordinator and provides a variety of support services to a venture company to help them successfully launch and develop their new business, such as offering individual consultations and a variety of information or advice. KSP, Inc. is well poised to cope with the varying needs of new ventures for highly sophisticated, specialized tasks by offering a business school, business support center, business matching services, and investment funds.The public sector, such as the Kanagawa prefectural government, Kawasaki city government, and the Development Bank of Japan, Inc., has an equity participation in KSP, thus playing a vital role in the deployment of local industrial development policy.

Investment focus

Biotechnology, Health Care, Medical
Funding Round, Series A, Series B
Japan

Portfolio highlights

3DC — 3DC develops and manufactures a new carbon material, graphene meso sponge (GMS), for electrodes in next-generation batteries, capacitors, fuel cells and other energy storage and generation devices.
THE PHAGE — The phage is a medical device company that focuses on developing AI technology to predict postprandial blood glucose levels.
Mira Robotics — Mira Robotics is a software based company provide services that can robots in various fields.

Takeda Ventures, Inc. (TVI) is the corporate investment arm of Takeda Pharmaceutical Company Limited (TPC). TVI was founded in 2001 and invests in current and future areas of interest for TPC. They are based alongside Takeda’s R&D sites in Cambridge, MA, and San Diego, CA. As a strategic investor, TVI aims to provide support and guidance toentrepreneurs and early-stage companies driving concepts through clinical proof of concept. They also strive to forge active, collaborative interactions that result in synergies with Takeda's considerable R&D resources. Their goal is to build a portfolio of strategic investments, with an immediate emphasis on oncology, gastroenterology, neuroscience, and rare diseases.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Funding Round
United States, United Kingdom, Israel

Portfolio highlights

Be Biopharma — Be Bio is developing a proprietary class of engineered B cells as medicines that unleash the potential of cell therapies in applications beyond cytotoxicity.
Larkspur Biosciences — Larkspur's strategy focuses on the particular ways in which tumours hijack the immune system by developing precision immunotherapies for molecularly defined patient groups to overcome the bottlenecks that allow the tumour to subvert the immune system.
EvolveImmune Therapeutics — EvolveImmune Therapeutics transforms the discovery and development of novel immunotherapies. By leveraging its proprietary in vivo target discovery platform, EvolveImmune is building a pipeline of novel therapeutic candidates against numerous targets that are expressed on multiple immune cell types. The company’s platform will generatefirst-in-class treatments for unmet needs in oncology and autoimmune diseases.

Takeda is a global, research and development-driven pharmaceutical company committed to bringing better health and a brighter future to patients by translating science into life-changing medicines.

Investment focus

Biotechnology, Health Care, Pharmaceutical
Grant, Funding Round, Corporate Round
United States, Japan, China

Portfolio highlights

Ascentage Pharma — As one of the leading clinical stage biopharmaceutical companies, we develop innovative therapies for global medical needs. Our biotech company is engaged in developing novel approaches for treating cancer.
Crescendo Biologics — Crescendo Biologics is a new Cambridge-based company whose vision is to deliver next-generation antibody therapeutics based on novel class-leading platforms.The focus of the company is on developing platforms that will address key issues in generating high-affinity, soluble, human VH antibody fragments. These are the smallest fragments thatretain antibody binding, and have many desirable properties as potential therapeutics. Crescendo will then utilise these platforms for product development of in-house targets or in partnership with other companies.
Atlanta Community Food Bank — We're on a mission to end hunger in our community. Learn more about how the Atlanta Community Food Bank provides hunger relief to families in need.

JIC-VGI helps promote innovation and improve its international competitiveness through growth-investments in startup companies. The firm accelerating innovation and helping to solve industrial and social issues by supporting and seeking innovative technologies and new businesses.JIC Venture Growth Investments was established in July 2020 and isbased in Tokyo, Japan.

Investment focus

Information Technology, Software, Financial Services
Series B, Series C, Funding Round
Japan, Singapore, Thailand

Portfolio highlights

MOSH Japan — MOSH is a web page creation services for individual business owners.
Gaudi Clinical — Gaudi Clinical is a health care firm that engages in regenerative medicine outsourcing and cell processing contract establishments.
Boston Medical Sciences — Boston Medical Sciences conducts research, prevention, and diagnostics procedures to eliminate colorectal cancer deaths.

Glocalink provides seed funding and comprehensive support for emerging science & technology entrepreneurs. Members of Glocalink have extensive experiences of bringing laboratory technologies to the market. On top of seed funding, we will provide comprehensive supports for overcoming all the hurdles that science / technology entrepreneursface.

Investment focus

Health Care, Robotics, Task Management
Funding Round, Seed, Series A
Japan, Singapore

Portfolio highlights

MOVeLOT — MOVeLOT is an AI company that provides skeletal platform and robot planning, development, and production services.
ExtraBold — ExtraBold specializes in the development of 3D printers.
ProfilePrint — Helping agribusinesses buy and sell better, ProfilePrint is powered by a patented digital food identity-as-a-service (IDaaS) technology. ProfilePrint synthesises complex molecular data of ingredient samples into digital fingerprints, rapidly predicting its identity and quality.

Kobe University Capital is create new indstry academia cllabration and technology transfer models.

Investment focus

Apps, Health Care, Health Diagnostics
Series A
Japan

Portfolio highlights

Pittan — PITTAN is a health tech startup that focuses on the development of high-speed analytical equipment for use in the healthcare industry. The company's primary service is to analyze the internal status of an individual's body to promote beautiful and healthy skin. This is achieved through the application of analytical chemistry.PITTAN's services are designed to provide insights into the body's health, which can be used to inform personal care and wellness decisions.
TelaAxon — TelaAxon develops artificial intelligence technology for sustainable operations, enhancing human-AI coexistence, safety, and wellness.
Alpha Fusion — Alpha Fusion Inc. is a clinical-stage startup committed to transforming cancer treatment through the design and development of powerful and precise radiopharmaceuticals.

Cosmo Bio provides the most up-to-date products and technical information available from world-class manufacturers, to laboratories, research institutes, life-science education and testing organizations throughout Japan and around the world. They are proud that their ability to supply a vast array of products and information allows us to serve theneeds of all of their customers. By making full use of their international network, coupled with the highest quality information, they support the life sciences community with a level of commitment and responsibility befitting a company that is trusted by its valued customers.

Investment focus

Medical, Biotechnology, Pharmaceutical
Seed
Japan

Portfolio highlights

Fimecs — FIMECS is a protein degradation technology-based drug discovery biotech focused on developing first-in-class protein degradation therapeutics for cancers and other difficult-to-treat diseases. The human body is comprised of at least 18,097 proteins.It has been revealed that 1,500 of them are related to certain diseases, nevertheless only about 300proteins have been regarded as druggable targets by small molecule drug discovery and all the rest have been undruggable.
Lab Biotech — Lab Biotech manufactures, conducts research, devises plans, and consults with pharmaceutical and food manufacturers.

Media Future is a group of communication technology professionals that works on connecting feelings and thoughts. The Tokyo, Tokyo-based company was established in 2013.

Investment focus

Medical, Biotechnology, Genetics
Series A, Funding Round
Japan

Portfolio highlights

HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.
HekaBio — HekaBio connects world-leading healthcare innovations to unmet medical needs in the Asia Pacific, with broad category development expertise in pharma, medical device, in-vitro diagnostics, digital health, and cell & gene therapies.
Jiksak Bioengineering — Jiksak Bioengineering is a biotechnology company. Jiksak Bioengineering provide an efficient screening service using a three-dimensional cell tissue "Nerve Organoid". We will mainly develop screening technologies specifically for neurodegenerative diseases and search for drugs that are effective for amyotrophic lateral sclerosis (ALS).

The Awa Bank provides financial services such as deposits, loans, and foreign exchange transaction.

Investment focus

Software, Automotive, Taxi Service
Series A, Funding Round
Japan

Portfolio highlights

DennoKotsu — Denno Kotsu is a Taxi dispatch system development and provision, taxi company contract dispatch service
Setsuro Tech — Seturotech Co., Ltd. is a biotechnology venture company established on February 22, 2017 by Tatsuya Takemoto (PI: Principal Investigator) of the University of Tokushima as a venture from Tokushima University. In 2015, Takemoto and Masakazu Hashimoto (Osaka University) developed a simple and highly efficient method for producing genetically modified(genome-edited) mice using CRISPR / Cas9, and filed a patent application for the technology. The technology is called fertilized egg electroporation (GEEP method), a technology that introduces molecules required for genome editing by CRISPR into fertilized eggs at high throughput by the power of electricity (electroporation). Using this technology, Seturotech will start from the production and sale of genetically modified mice, and will become a fundamental company providing all genetically modified animals, anticipating the future use of genetically modified animals in industry.

Yokohama Capital as a venture capital firm conducts investment and rehabilitation support for small and medium-sized companies.

Investment focus

Health Care, Artificial Intelligence, Manufacturing
Funding Round, Series A, Series B
Japan

Portfolio highlights

Any — any. develops and offers knowledge sharing tool Qast.
KOMPEITO — Office de Yasai is an online platform that enables users to order and get vegetables delivered to their offices. The platform’s operations are based in Tokyo, Japan.
PXP — PXP is a green tech development firm that develops clean energy using next-generation photoelectric conversion elements.

Capital Medica Ventures is a venture capital firm based in Tokyo, Japan with a focus on startups in the healthcare industry.Capital Medica Ventures is a venture capital that operates a venture fund specializing in the healthcare field. It is the only healthcare-specialized VC in Japan that can provide 30 medical institutions as a business trialfield.

Investment focus

Medical, Software, Health Care
Seed, Series A, Funding Round
Japan

Portfolio highlights

HCMJ — HCMJ specializes in software development in the medical industry.
Epigno — Epigno provides hospital management systems for medical institutions.
Rehab — Rehab for Japan is developing a special rehabilitation SaaS for day service .

Global Brain Corporation is a venture capital firm that invests in companies from seed or early to pre-IPO startups. Global Brain has invested in 300+ startups from seed/early to pre-IPO startups and achieved 25 IPOs and 61 M&As as a result of providing hands-on support services and resources to its portfolio startups. Global Brain hasmanaged a pure investment fund as well as multiple corporate venture capital funds partnered together with tier 1 public companies of telecom, real estate development, financial service, beverages, agriculture food, logistics, and electronic devices.

Investment focus

Information Technology, Software, Artificial Intelligence
Series A, Series B, Funding Round
Japan, United States, United Kingdom

Portfolio highlights

Cellid — Cellid developing the waveguide-architecture display module for AR glasses and high-performance spatial recognition software.
Tokenz — Tokenz is your all-in-one platform for global digital payments, cross-border tax compliance, and seamless payouts.
Boston Medical Sciences — Boston Medical Sciences conducts research, prevention, and diagnostics procedures to eliminate colorectal cancer deaths.

Fujifilm develops and sells consumer products and business products related to photography. Fujifilm Holdings Corporation is a Japanese multinational photography and imaging company. The company serves various industries, including medical, graphic arts, optics, enterprise storage, motion picture, and photography.The company’s consumer productsare categorized as digital cameras and accessories, film photography, Instax photography, and binoculars. Its business products are categorized as medical systems, Fujinon endoscopy, microfilm, data storage, graphic arts and printing, professional video, optical devices, specialty chemicals, printing imaging colorants, and more. Color films, digital cameras, photofinishing equipment, color papers, photofinishing chemicals, medical imaging equipment, graphic arts equipment and materials, flat panel displays, and photocopiers and printers are some products developed by Fujifilm USA.Fujifilm USA is based in Minato-ku, Tokyo, Japan.

Investment focus

Biotechnology, Medical Device, Medical
Series A, Funding Round, Series B
Japan, Israel, United States

Portfolio highlights

Ripcord — Ripcord is a robotics company that combines hardware and software robotics via an integrated SaaS offering. Its focus is on smart robotics digitization, smart content management with AI, and helping enable RPA and business processes.Ripcord is based in Hayward, California, and is backed by leading investors Kleiner Perkins Caufield & Byers,Google Ventures, Lux Ventures, Legend Star, and Apple Co-Founder Steve Wozniak.
Rege Nephro — Rege Nephro is a biotech company that specialized in R&D, production and marketing of renal disease therapeutics.
24M Technologies — 24M Technologies develops energy storage systems for grid and transportation applications. 24M Technologies, Inc. builds energy storage systems for grid and transportation applications. The company was founded in 2010 and is based in Cambridge, Massachusetts.

Primal Capital, an independent venture capital " incubator bait fund at ", served as the Associate than July 2012 Hiroshi was Sasaki is the venture capital fund that serves as the representative partner. Representative of Sasaki, the seed acceleration program "Incubate Camp" operated by Incubate bait fund is carried out a totalof four times of planning and management than in 2012, They have also engaged in support operations of portfolio companies. - See more at: https://www.crunchbase.com/organization/primal-capital#sthash.m2z1DCbt.dpuf

Investment focus

Software, Information Technology, Internet
Seed, Funding Round, Pre-Seed
Japan, Spain, Switzerland

Portfolio highlights

Hivello — Hivello is a Decentralized Physical Infrastructure Network aggregator. Contribute resources, connect with Web3 protocols, and effortlessly generate passive income.
RemitAid — RemitAid is a fintech company that operates an overseas payment platform for cross-border transactions between companies.
xCARE — xCARE specializes in the development and commercialization phases of the pharmaceutical and medical device industries.

SPARX Group Co., Ltd. is an independent Asia-based equity and credit asset management services and Asian fund financial specialist with offices in Tokyo, Hong Kong and Seoul for global institutional and individual investors, including financial advisors and financial planners, with alternative strategies (including activist, short-enabled, private equity and quantitative and fund-of-funds) and mutual funds (through SPARX Asia Funds such as SPARX Asia Pacific Opportunities Fund, SPARX Asia Pacific Equity Income Fund, SPARX Japan Smaller Companies Fund and SPARX Japan Fund) managed or sub-advised by SPARX Asset Management Co. Ltd., SPARX Asia Investment Advisors Limited and Cosmo Asset Management Co., Ltd.

Investment focus

Software, Artificial Intelligence, Information Technology
Funding Round, Series B, Series A
Japan, United States, China

Portfolio highlights

Blue Skies Space — Blue Skies Space provides access to space science data from low-cost space missions.
Blue Laser Fusion — Blue Laser Fusion is a commercial fusion company. Blue Laser Fusion is a laser startup to commercialize laser fusion by inventing its own laser and fusion reactor.
Nanofiber Quantum Technologies — Powering a globally connected quantum future with pioneering nanofiber cavity QED.

Kyogin Lease & Capital is an investment firm that specializes in the leasing, stock and bond investment and public offering consulting.

Investment focus

Manufacturing, Task Management, Medical
Funding Round, Series A, Series B
Japan

Portfolio highlights

Thinca — Thinca is an IT system planning, development, and operations company that provides a cloud-based CTI (Computer Telephony Integration) hospitality & communication solution for corporate offices.
Towing — Towing is an agricultural company that provides farming, manufacturing, and recycling services.
Regional Fish — Regional Fish provides seed, seedlings, aquaculture methods and fisheries services.

Ohara Pharmaceuticals is a pharmaceutical business involved in the development, manufacture, and distribution of pharmaceutical products.

Investment focus

Medical, Biotechnology, Nursing and Residential Care
Series A, Funding Round, Series B
Japan, Kenya, Nigeria

Portfolio highlights

HACARUS — We make AI work, where common Big Data aproaches fail. Get explainable results, even from small data amounts. Available on the cloud or as embedded devices.
Helium Health — Helium Health empowers healthcare providers in Africa with digital tools, financing solutions, and data partnerships. Learn more about our innovative solutions.
Revital Healthcare — Revital Healthcare is a manufacturer of medical devices and disposables for hospitals and other medical laboratories. It offers single-use syringes, needles, re-use prevention syringes and auto-disable syringes which helps in reducing the transmission of HIV and other blood-borne diseases along with infusion sets, blood transfusion sets and bloodcollection tubesThe company was established in 2006 and is headquartered in Kilifi, Kenya.

Angel Bridge is a angel investor groups in Japan and provide high quality and abundant funds to excellent companies.

Investment focus

Consulting, Information Technology, Software
Seed, Series A, Funding Round
Japan

Portfolio highlights

Amptalk — Amptalk is a software development firm specializing in operating automatic transcription and analysis of online business negotiations.
PartnerProp — PartnerProp is a PRM tool with outstanding potential and a wide variety of capabilities that resolves all partner business difficulties.
Simple Form — Simple Form provides real-time information on all domestic corporations necessary for financial institutions. We will accelerate the time-consuming and labor-intensive research work of corporations and take on the role of new financial underpinnings.

TechAccel Ventures is a Seed and Early-Stage Venture Capital firm focused on technology startups in Japan. The firm contributes to the development of the Japanese industry by providing investment and support based on a technical perspective.

Investment focus

Manufacturing, Information Technology, Information Services
Funding Round, Series A, Series B
Japan, United States

Portfolio highlights

SIRU+ — SIRU+ is a startup that enables you to convert consumer purchasing data into nutrients and visualize and quantify consumer shopping trends. Through the app developed by the company, consumers can know their nutrition status. The service “SIRU+ (SIRU+)” is an app that lets you know the nutrition of what you bought by simply registering a super pointcard.
EAGLYS — EAGLYS provides a platform for secure computing and AI.
KOALA Tech — Koala Tech Inc. is an innovative high-tech startup company, whose goal is to pioneer practical applications of the world's first organic semiconductor laser diode that has been realized in the Center for Organic Photonics and Electronics Research (OPERA) at Kyushu University.

JAIC is Japan's largest independent venture capital firm and has accumulated experience and know-how over a period of 15 years as a pioneer of venture capital investments in Asia. Building on such strengths, they are establishing a globally linked organization that pursues investment opportunities centering on the three regions of Japan, Asia,and the United States.

Investment focus

Medical, Biotechnology, Health Care
Series B, Funding Round, Series C
Japan, United States, China

Portfolio highlights

FacePeer — FacePeer is looking for people who want to challenge at startup.
REGiMMUNE — REGiMMUNE Corporation is a private biopharmaceutical company developing innovative solutions for treating immune disorders caused by nonspecific and/or excessive immune reactions. REGiMMUNE uses its proprietary technology platform, reVax (reverse vaccination), to target immune tolerance against specific disease-causing antigens throughinduction of regulatory T cells (Treg). This technology has potential applications in a number of immune system disorders and diseases including Graft versus Host Disease (GvHD), type 1 diabetes mellitus (T1DM), rheumatoid arthritis (RA), multiple sclerosis (MS) and systemic lupus erythematosus (SLE).Currently, the company has one clinical-stage compound in a Phase I/II trial in the United States (RGI-2001) as a treatment for GvHD associated with hematopoietic stem cell transplantation and has a second product in preclinical development (RGI-3001) as a new treatment for T1DM. In addition, it has a number of well-differentiated compounds in its research-stage pipeline.In healthy individuals, the normal immune system works to protect humans from disease-causing viruses, bacterium, and cancers; or foreign antigens such as peanuts, wheat and tree pollens. Conventional immunosuppressants have several significant side effects associated with long-term administration including risk of infection, toxicity and relapse. Products developed with ReVax technology are expected to reduce or eliminate such side effects as well as reduce long-term treatment.
Integral Geometry Science — Integral Geometry Science is a specialized manufacturer of measuring equipment and signal / image processing software.

Fuyo General Lease focuses in the leasing and installment sales trading of equipment and fixtures, and financial transaction. The company provides leasing services of information-related equipment, office equipment, and industrial equipment, installment sales of commercial facilities, production facilities, and hospital facilities. It also providessecurities management services and anonymous association composition.Fuyo General Lease was founded on 1969 and is headquartered in Tokyo, Japan.

Investment focus

Manufacturing, Biotechnology, Sales
Series A, Funding Round, Corporate Round
Japan

Portfolio highlights

avatarin — avatarin develops next-generation mobility and human augmentation platforms.
A.L.I.Technologies — Aerial Lab Industries focuses on research and development of UAV (unmanned miniature aircraft).
3D Printing Corporation — 3D Printing Corporation provides 3D printing technology solutions.

Innovation Network Corporation of Japan (INCJ) is a public-private partnership aimed at promoting innovation and enhancing value.Leveraging the rich history of Japanese technological prowess, INCJ aims to provide financial, technological and management support in order to promote the creation of next-generation businesses through “openinnovation,” or the flow of technology and expertise beyond the boundaries of existing organizational structures.INCJ will draw on funding as well as management and technological expertise from the public and private sectors. INCJ is actively reviewing various investment opportunities in areas of green energy, electronics, IT and biotechnology to infrastructure-related sectors such as water supply. Each investment will be thoroughly vetted to ensure it meets the exacting standards of INCJ's Innovation Network Committee, which will make the final investment decisions.INCJ is capitalized at 280 billion yen, with the Japanese government injecting 266 billion yen and 26 private corporations (refer to details in Appendix below) providing a further 14 billion yen. The government will also provide guarantees up to a total of 1,800 billion yen for INCJ investments, giving it an investment capability of approximately 2,000 billion yen. INCJ will be established for a period of 15 years.

Investment focus

Manufacturing, Software, Robotics
Funding Round, Series B, Series A
Japan, United States, United Kingdom

Portfolio highlights

Cloudian — Cloudian provides exabyte-scale storage for your capacity-intensive workloads: S3-compatible storage for on-prem, hybrid cloud, and multi-cloud.
Seajacks — Cadeler is a global leader in offshore wind farm construction, maintenance, and decommissioning.
Vehicle Energy Japan — Vehicle Energy Japan specializes in development, manufacturing and sales of automotive lithium-ion batteries.

The Japan Medical Device Development Organization aims to activate Japan's medical innovation and medical device industry, centering on the medical device incubation business, and aim for Japan to become a world leader in this field.Japanese Organization for Medical Device Development is a country of craftsmanship, possesses high technicaland quality control skills, and should be good at producing medical equipment. However, in the medical device field, imports exceed 600 billion yen every year. Japan's “manufacturing” technology has not been fully utilized.

Investment focus

Biotechnology, Laser, Medical
Seed, Series A, Funding Round
Japan, United States

Portfolio highlights

Luxonus — Luxonus is a product development of a new imaging device using optical ultrasonic technology.
Meltin MMI — Meltin MMI is a cyborg-technology company that focuses on biosensors and robotic arms. Meltin has successfully enabled fine finger movements, such as for amputees and participated in Cybathlon 2016 and won the Microsoft Innovation Award.
Genomelink — Genomelink is a platform where people discover more with their DNA data and help businesses build, market and do research with it. The best founders in consumer genomics with real experience in the industry for many years, including M3, Inc. ($13B valued Meditech in Japan), a founding member of the Japanese version of 23andMe, and leadbioinformatician and software engineer at a joint-venture between Illumina and Sony. Raised $4M for Seed Round from Berkeley SkyDeck, SONY, and top-tier Japanese VCs. Supported by Illumina Accelerator, Carlos Bustamante Lab at Stanford University among others.

The University of Tokyo IPC is a company responsible for expanding the innovation ecosystem of the University of Tokyo. Accelerate global innovation from the University of Tokyo through three activities: start-up support, investment business, and corporate innovation support.It was established as a wholly-owned subsidiary of the University ofTokyo in 2016 with the enforcement of the revised law of the Industrial Competitiveness Enhancement Law, which is the basis law. The investment targets of the Todai IPC are venture companies that utilize the research results and human resources of the University of Tokyo, but they also make FOF (fund of funds) investments in funds managed by some private venture capital companies. In 2019, it started a consortium-type incubation program (University of Tokyo IPC 1stRound) to support the establishment and financing of Tokyo University-related ventures.

Investment focus

Biotechnology, Medical, Manufacturing
Series A, Funding Round, Series B
Japan, United States, United Kingdom

Portfolio highlights

Issin — Issin manufactures bath mats that can measure weight and automatically record daily weight changes on your smartphone.
BlueWX — BlueWX is a software company that develops predictive content services that supports in forecasting, and weather analysis.
Leading Mark — Leading Mark, a rising human resources startup in Japan. Leading Mark is branching out into mid-career and international hiring. It currently has a one-man team in China working to bring the top Japanese-speaking Chinese students to domestic companies. He also touts his startup’s focus on the average job seeker. “We want to make sure that the usersget the info that he or she needs the most,” he says. Large scale, legacy players can sometimes prioritize the needs of the hiring company, and their commission, over the needs of applicants themselves. This leads to frustration and short-circuited careers.

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