Top 50 Cryptocurrency Startup Investors in Spain (October 2026)

Portfolio highlights

• Tolemy Bio — The AI-native virtual cell platform for therapeutic development and manufacture.
• Charms — Charms AI is an on‑chain mobile application focused on AI characters with persistent memory and user‑facing economies. The platform allows creators to build AI characters that can maintain long‑term conversational context and have their own wallets and tokenized assets, while users interact with, back, and trade around those characters. It sits atthe intersection of AI‑driven interaction, gaming‑style engagement, and blockchain‑based tokenization, with the overall design geared toward converting user attention and interaction into on‑chain economic flows.
• Balance — Balance is a private digital health company based in Spain that operates in the clinics and outpatient healthcare services sector. company's core mission is to provide an integrated, medical, and sustainable approach to treating obesity and overweight conditions. Moving away from traditional restrictive diets, the company leverages asubscription-based telehealth model combined with clinical pharmacology.

Portfolio highlights

• Mirai — Mirai offers solutions for balance sheet management, financial risk, and regulatory compliance.
• Inventia Kinetics — Inventia Kinetics specializes in the design, analysis, and manufacture of equipment and assembly tools for electronics sector.
• Connecta Therapeutics — Connecta Therapeutics is a biotechnology company that develops new treatments for unresolved medical needs of the central nervous system. It focuses on the development of a first-in-class drug for the treatment of fragile X syndrome.

Portfolio highlights

• Wixpool — Wixpool is a liquidity mining mechanism that is based on the Wixpool Rate Stabiliser (WRS) algorithm. Wixpool, led by WRS, allows anybody to invest in high-yield liquidity pools with a steady interest rate by pooling the assets of private users into an automated ecosystem.
• Elixir — Powering deUSD, a yield bearing and fully collateralized decentralized dollar on the Elixir Network, bringing institutional-grade liquidity to RWAs.
• Frontrunner — Alexistogel atau di kenal sebagai alexistoto adalah salah satu situs slot yang sudah terpercaya dengan banyaknya yang ingin maxwin hari ini

Portfolio highlights

• TrueDAO — TrueDAO is a new-generation AI-native decentralized autonomous financial infrastructure. Built on the underlying logic of DAO community co-governance, it leverages smart contracts to construct an on-chain financial system integrating AI algorithm scheduling, staking, and dynamic protection. It optimizes economic parameters and asset strategies inreal time via AI models, delivers low-volatility and sustainable value growth paths for digital assets, and pioneers an innovative paradigm of autonomous finance.
• Cryopets — Pausing biological time with cryosleep for pets
• Share — From subsea cables to last-mile networks, Share coordinates fragmented infrastructure into a single ecosystem.

Portfolio highlights

• Talstack — Talstack is an all-in-one platform for employee growth and development
• MAKA — MAKA is a community commerce platform for fashion and beauty, enabling everyone to discover their style, feel represented.
• Renda — At Renda, we are passionate about revolutionizing the logistics and mobility sectors with cutting-edge technology that enables businesses and operators to seamlessly scale in emerging markets.

Portfolio highlights

• Enjinstarter — Web 3.0 Entertainment, Sports, Fashion, Metaverse, Social, Gamefi & Gamified Utility
• Zeitgeist PM — Zeitgeist PM is a blockchain tech to facilitate prediction markets and the futarchy form of governance.
• Genesis Shards — Crafting a whole new suite of NFT powered products across multiple blockchains

Portfolio highlights

• DePay — DePay is an Argentina-based real-time payments infrastructure startup.
• Diameter Pay — Diameter Pay is a financial service company that provides financial inclusion, fintech, blockchain, and social entrepreneurship services.
• City Protocol — City Protocol offers growth incentives and creative tools driven by AI. A portable reputation is created via City ID.

Portfolio highlights

• Portal — Build next-generation cell engineering and drug discovery workflows with Portal mechanoporation for broad intracellular delivery across cells and cargoes.
• Superapp — Build iOS, Mac and Apple Watch swift native apps and games with AI. One click to App Store & ASO. Join Superapp Discord https://t.co/klNe8391Vw
• Portal AI — Personal AI agent that actually knows who you are

Portfolio highlights

• Tare — Tare uses AI and tokenization to change the entire credit lifecycle.
• Bloom — Moved to @bloomsocial
• Lemon Cash — Lemon Cash is digital wallet with FIAT and crypto capabilities. End to end digital ecosystem for Latin America.

Portfolio highlights

• Tea-Fi — Tea-Fi is an all-in-one decentralized finance (DeFi) platform that turns complexity into opportunity.
• Finceptor — Become an early investor of Web3's top projects with over 250,000 other backers.
• web3intelligence — Build wealth and trust in the world of crypto with intelligent financial tools, data and infrastructure.

Portfolio highlights

• Jota — Jota: The platform handles finances for individual entrepreneurs and business owners by allowing them to instantly pay, collect receivables, and manage their day-to-day operations with voice notes, text messages, and images through an AI-first chat conversation. All tasks are free and executed in seconds. Designed to save time and money, Jotaempowers its clients to focus on what truly matters to them.
• Flextock — Discover efficient order fulfilment with Flextock. We streamline your inventory, orders, and shipping, ensuring accuracy and cost-effectiveness.
• OnSite — OnSite is a messaging and communication platform built specifically for construction and field‑service teams. It helps teams coordinate tasks, share updates, and manage project‑related information directly within a chat‑style interface. The platform also turns routine conversations into structured documentation to reduce manual admin work and keepproject records organized.

Portfolio highlights

• Hirevoice — Hirevoice is a voice AI recruiter that runs structured voice AI interviews with every candidate and gives your team defensible hiring signal. Book a demo.
• dimenso.ai — Dimenso AI develops software that uses voice and computer vision to capture laboratory activities in real time. Its technology integrates this information with laboratory information management systems (LIMS). It is designed to replace or supplement traditional laboratory notebooks with digital records of experimental activities.
• Spacebackend — Lynapse by Spacebackend unifies interface modeling, version control, testing, and validation. Convert ICDs into traceable, deterministic implementations with human-in-the-loop review.

Portfolio highlights

• ABSORA —
• Atrya — Atrya develops regulatory-compliant blockchain payments for international companies.
• Punto Health — AI-Powered, Personalised Support for Every Patient and Family

Portfolio highlights

• Nestcoin — Nestcoin is a web3 application company that builds, operates, and invests in crypto-native products.
• Defy — Defy : India's first social crypto exchange - Buy, Sell & Trade Crypto instantly and easily with INR at the best prices
• Doorbell Health — Your front door to home health.

Portfolio highlights

• Aloja — Aloja is an autonomous AI-driven dynamic pricing platform built specifically for tours, activities, and attractions.
• Flipflow — At Flipflow, we offer brands, manufacturers, and retailers an accurate, actionable, real-time snapshot of their products, competitors, and the market to facilitate informed business decisions. We gather millions of data points daily from retailers in markets worldwide. This data is processed, structured, and delivered as real-time actionableinsights through a flexible and powerful Business Intelligence (BI) suite. Our suite incorporates automations and AI-powered analytics, providing prescription capabilities that guide different teams within retail companies to make optimal business decisions. This approach not only offers a more holistic perspective for key decisions but also enhances day-to-day reaction capabilities.
• Kalipso — Kalipso automates regulatory compliance with smart mapping and policy update tools.

Portfolio highlights

• Artela — Artela is an extensible L1 blockchain with parallel execution and modular VMs. With key innovation of EVM++, Artela enables modular, customizable, and scalable dApps.
• Diva — Diva Staking is an Ethereum Liquid Staking protocol powered by distributed validators and a set of permissionless node operators. Join our community and become part of Diva.
• CEBG Studio — CEBG Studio is a gaming studio.

Portfolio highlights

• ZKON Network — Zero Knolwedge protocol to attract volume and liquidity
• Myriad — Myriad Markets is a decentralized prediction‑market protocol that lets users trade short‑term, outcome‑based markets on events across crypto, sports, politics, gaming, and culture.
• Amnis Finance — Stake APT on the best liquid staking protocol on Aptos to receive daily rewards with an attractive APR of 2%.

Portfolio highlights

• ZAP — ZAP offers a reputation-based token distribution protocol that supports fair rewards for user contributions within the Blast ecosystem. It enables users to participate in various projects through missions and seamless investment options. Additionally, ZAP is expanding its services to other blockchains and developing tools to simplify access toventure-capital-backed projects.
• Agent — All-in-one platform to create and manage Web3 Sub-Accounts to earn points from dApps. Trade accounts even before TGE / airdrops.
• Blast — The Fullstack Chain

Portfolio highlights

• Myka.Insure — Myka is a insurance sales platform that enables individuals to sell insurance policies to their family, friends, colleagues, and community while earning income . It operates as a micro-entrepreneurship program where anyone (students, gadget sellers, car dealers, parents, retirees) can start their own insurance business with zero investment,flexible hours, and free training . The company is licensed by the National Insurance Commission of Nigeria and provides instant payouts to its partners .
• Cybervergent — Cybervergent is a technology company that specializes in providing top-notch cybersecurity solutions to businesses and organizations.
• Traction Apps — Traction apps provide businesses end to end tools they need to run and grow their businesses.

Portfolio highlights

• HUNTY — HUNTY is a platform that help people find jobs by connecting them with world class mentors who prepare them for the job search process. And people only pay when they get hired.
• Duppla — Duppla operates as a rent-to-own startup focused on providing alternative financing solutions for home buyers in Colombia. It offers a unique approach to homeownership, where traditional debt is not the primary mechanism. Instead, Duppla presents an innovative model that facilitates access to housing through alternative financing methods. Thisapproach is designed to make the dream of owning a home more attainable for individuals and families, particularly in the LATAM region. With a team that includes co-founders and experts with backgrounds in research and strategy from notable companies, Duppla leverages its understanding of organizational context and user experience to tailor its services. The company aims to address the challenges of affordable housing financing, making it easier for customers to navigate the path to homeownership.
• Simetrik — Automate repetitive data reconciliation processes without any coding knowledge

Portfolio highlights

• Baobab Studios — Creating VR animation experiences to bring out your sense of wonder and inspire you to dream again.
• Firelight — Firelight is a DeFi protocol that allows XRP holders can stake tokens and help cover risks on DeFi platforms.
• Alkemya Luxembourg — Alkemya Luxembourg is an international high tech metals firm specializing in sourcing and distributing rare earth oxides, titanium, and nickel wire, that are increasingly important to R&D and manufacturing companies in semiconductor, aerospace, and other high technology industries.

Portfolio highlights

• Lingawa — Speak your native language with pride! Learn Yoruba and Igbo with fun, immersive online lessons for adults and kids (ages 5+).
• Maad — Maad is Francophone Africa's fastest-growing B2B marketplace, based in Dakar, Senegal. Our tech-driven solution allows retailers to order products from our one-stop shop and benefit from working capital loans
• ZeroComplex AI — Transform your Business with AI. Click the Link below to get started!

Portfolio highlights

• nFuse.ai — nFuse scales your B2B sales with AI. Up to 30% revenue uplift, $1 per order processing cost, live in 30 days. No new apps, no behavior change.
• Veridion — Veridion is a living digital replica of the business world. Decision-grade data for enterprise scale systems
• Nanogram — Nanogram is an AI-powered gaming startup that creates an instant prompt-to-game platform, allowing anyone to build and share interactive short-form video games. Frequently described as "TikTok for mobile games," the company delivers an endless, vertical social feed of byte-sized, zero-download games that players swipe through and playinstantly.

Portfolio highlights

• Tessera — Fractional is a decentralized protocol that enables collective ownership and governance of one or more NFTs
• Permian Labs — Earn yield in the Metaverse with leverage.
• MetaStreet — Developed by @PermianLabs | backed by @Dragonflly_xyz, @DCGco, @AllianceDAO

Portfolio highlights

• Jeeves Inc. — Pay for anything, anywhere, in your local currency. No fees. No interest. No personal guarantees. Mobile-first, built with your team in mind.
• EDGE Markets — The Financial Platform for Smart Bettors
• LI.FI — Advanced Bridge & DEX Aggregation - Drive multichain strategies with cross-chain data messaging and get users from everywhere.

Portfolio highlights

• STEM Cafe — STEMCafe by RVRB is a fun out of school learning centre for kids
• Juicyway — The new shape of money? Fluid. Access global currencies with Juicyway. Buy, sell, hold, and pay globally using our fast APIs, web, or mobile apps. Download now.
• Lori Systems — Lori Systems is revolutionizing African logistics through innovative technology solutions. We connect shippers, transporters, and drivers to create efficient, reliable, and transparent supply chains across Africa.

Portfolio highlights

• Anda Africa — Anda is Angola’s leading mobility fintech platform, providing asset financing, ride hailing, and delivery services to empower mobility entrepreneurs. Built for emerging markets, Anda bridges the credit gap by financing productive assets such as motorcycles, tricycles, and cars, enabling drivers to own their vehicles, increase their earnings, andenter the formal economy. Through technology driven credit profiling and fully digitized payments, Anda creates financial identities for people who were previously underserved and unlocks responsible access to financial services. As an impact driven company, Anda brings together mobility, financing, and digital payments to deliver safe, affordable, and inclusive transportation while enabling a new generation of financially empowered entrepreneurs.
• Aether Bio — Aether uses its state of the art platform to rapidly engineer enzymes, enabling our customers to manufacture complex and novel products at fractional cost.
• Aethex — End to end voice agents localized for your market.

Portfolio highlights

• Midi Health — Expert care for women 40+. Made for midlife. Delivered by experienced clinicians. Covered by insurance. Book a visit today.
• Ours Privacy — Privacy platform and customer data platform for healthcare.
• Formulary Financial — Formulary Financial is a modern fund administrator that combines best-in-class talent and technology to deliver unparalleled partnership for GPs and LPs.

Portfolio highlights

• Beldex — Beldex is a private ecosystem consisting of decentralized applications. The Beldex privacy coin (BDX) is a utility coin of the Beldex private ecosystem.
• Superset — The Unified Execution Layer for stablecoins, tokenized deposits, and onchain FX. One shared liquidity market, accessible across all chains.
• ZenChain — The first decentalised Bitcoin EVM L1 bringing smart contracts, composability, and true cross-chain liquidity to BTC.

Portfolio highlights

• 3Commas — 3Commas develops a crypto-asset management tool for tracking investments and exchanges in a unified platform. It provides access to a unified dashboard as the central hub for trading and portfolio management execution.
• Fuel Labs — At Fuel, we are building the fastest execution layer for the modular blockchain stack.
• Optim Finance — Optim Finance provides investment tools that optimize yield on digital assets. Their financial primitives enable users to rent ADA delegation rights to power novel use cases such as SPO loans, leverage into ISOs, and initial bonds.

Portfolio highlights

• Redpill AI — Access 200+ AI models with privacy-first infrastructure. Private models in GPU TEE, OpenAI-compatible API, zero data retention.
• Yellow — Yellow is a financial services provider of software, analytics, and investments in blockchain startups.
• Konnex World — Building the GDP of autonomous systems. Turning robot labor into on-chain liquidity. $KNX

Portfolio highlights

• Citring — Citring One, is an innovative juicer with a radically simplified process. Effortless from juicing to cleaning, it is ideal for anyone with a busy lifestyle. Say goodbye to hassle and hello to fresh juice. With Citring One, juicing is as easy as pressing a button.
• Vinkova — Vinkova specializing in high-quality, customizable rhythmic gymnastics leotards, training wear, apparatus, and performance accessories.
• Cocircular — Cocircular is a Construction Company.

Portfolio highlights

• Cribdata — Showcasing premier real estate in a city near you! Interested in having us feature your newest listing? Contact us! cribdata.sales@gmail.com
• Intelia — Intelia specializes in web design and web development services.
• Union Avatars — Union Avatars is the fastest and easiest avatar maker to create your realistic avatar from a single selfie. Try it now for free.

Portfolio highlights

• Akave Cloud — The Al-Ready Sovereign Cloud | Own your data. Control your costs. A modern S3-Compatible object storage.
• Hemispheric — Hemispheric develops fundamental AI technologies aimed at deciphering brain activity for innovative applications.
• Synchron — The endovascular brain computer interface.

Portfolio highlights

• revert — Actionable analytics, lending, and automation for AMM liquidity providers.
• Rysk Finance — Earn uncorrelated returns with Rysk, the DeFi protocol that leverages risk-managed credit vaults. Depositors benefit and earn from sophisticated market making, trading strategies, fees and rewards. Start earning today.
• SpaceComputer — SpaceComputer uses satellites to create a secure blockchain system that resists cyberattacks and physical tampering.

Portfolio highlights

• Blast — The Fullstack Chain
• Monad — Monad brings true performance as a new EVM L1 blockchain. Fast, powerful, efficient. Built for developers.
• Stable — The StableChain powered by USDT. Backed by @Bitfinex, @PayPal Ventures and @USDT0_to.

Portfolio highlights

• EarnOS — EarnOS is the fully remote company that provides Global Ad & Payments Platform powered by Web3.
• KOR Protocol — KOR Protocol is a decentralized intellectual property (IP) infrastructure designed to empower creators, protect rights, and enable seamless collaboration and monetization of IP assets across various industries, including music, film, TV, gaming, and art. Backed by notable entities like Animoca Brands, Republic, Niantic, Sfermion, Solana, andprominent creators such as Black Mirror, Disclosure, deadmau5, and Richie Hawtin, KOR leverages blockchain, AI, and DeFi to offer a transparent, efficient, and scalable environment for IP expansion.
• Freehand — AI Teams for Complex Spend Management

Portfolio highlights

• ZeroBrush — Clean every surface of your teeth, every time, all at once. ZERObrush is a groundbreaking oral care mouthpiece built from a 3D model of your teeth and designed to clean the hard to reach places better than a manual toothbrush.
• Biz AI Last — Your dedicated IT department. AI-assisted triage, live expert support via chat, remote connection to fix issues directly, and on-site technicians when needed.
• Mast Reforestation — No-cost reforestation for post-wildfire burned acreage for landowners and foresters, funded by carbon removal credits.

Portfolio highlights

• Tripjoin — Tripjoin brings together those who want to travel but don't have anyone to travel with. Everyone joined with the same goal of meeting new people and experiencing travel in a unique way.
• Uxia — Transform your research with AI-powered user testing, delivering high-quality UX/UI insights for Product Designers and UX Researchers. No recruiting needed.
• Mathew — Mathew is an educational platform that provides AI-powered software for teachers and students.

Portfolio highlights

• Thndr — Egypt's #1 investing platform by active users. Stocks, gold and mutual funds in one app, licensed and regulated by the FRA. Start with what you have.
• Ezeebit — Ezeebit is a payment solutions provider that enables African merchants to accept cryptocurrency payments both in-store and online. The platform processes transactions quickly and automatically converts the cryptocurrency into stablecoins to eliminate volatility risk. Funds are then settled into the merchant's local currency account, typicallySouth African Rand (ZAR), on the next business day. The company offers multi-currency support for popular cryptocurrencies like Bitcoin and Ethereum and maintains compliance with financial regulatory bodies.
• Letly — Letly is developing an AI‑driven platform for the rental property market that automates tasks related to managing rental listings and tenant interactions. It aims to use intelligent agents to handle tasks such as scheduling viewings, responding to inquiries, and optimizing property management workflows. The platform is currently in a waitlistphase, signaling ongoing development and private access only.

Portfolio highlights

• V12 — Tune V12 to your codebase. Investigate security findings with the source, a reproducible proof, and a concrete fix.
• InfiniFi — backup infiniFi account. Main infiniFi account - @infiniFi
• Legend. trade — Where traders become Legends.

Portfolio highlights

• XMTP — XMTP is a decentralized and quantum-resistant messaging protocol for builders.
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.
• Superstate — Superstate is modernizing investing through tokenized financial products

Portfolio highlights

• Atum — Atum is the open payments network that coordinates those systems.
• Tenor Labs — Tenor helps people borrow and lend money at a fixed rate without needing permission.
• Hello Clever — Connect every rail and understand every payment. Unify your payment infrastructure with Clever AI to instantly turn transaction data into measurable growth.

Portfolio highlights

• Shardeum — Shardeum is an EVM-based, linearly scalable smart contract platform that maintains low gas fees while providing true decentralization and solid security
• Paxo Finance — Supply single-sided liquidity to earn risk-free yield or use leveraged investment vaults to supercharge your DeFi strategies.
• Push Protocol — Push (Previously EPNS) | Communication Protocol of Web3

Portfolio highlights

• BeraTone — BeraTone is a farm life simulation game developed on Berachain technology.
• SkyTrade — Govern and Monetize Low-Altitude Airspace. Backed by: @modular_capital @portalventures @solanafndn @ZeePrimeCap
• Uranium Digital — here for the green

Portfolio highlights

• Synnax — Synnax is an artificial intelligence-powered financial platform which helps to forecast financial performance
• StarSharks — StarSharks is a NFT-GameFi ecosystem based on the BSC chain developed by game players, governance committees, and game developers. The game integrates different types of games and breaks down barriers found between games by allowing players to use the same character to enter the Shark-metaverse. It enables players come together to build and govern a new metaverse and create a community culture in the Shark-metaverse.
• Chain of Alliance — Chain of Alliance want to allow players to create their own campaigns and stories. They will be able to use our API, and other players staked and offered Characters and land. Their currency offers the characters that are represented as non-fungible tokens can be staked to earn.

Portfolio highlights

• Atrya — Atrya develops regulatory-compliant blockchain payments for international companies.
• Robin Markets — Earn yield on Polymarket positions.
• Ethereum Institutional — Accelerating institutional adoption of Ethereum

Portfolio highlights

• SYNTHR — SYNTHR is redefining instant and slippage-free asset movement across chains
• Cryptoverse — Cryptoverse develops a 3D metaverse composed of a collective imagination.
• Bora Finance — Bora Finance is a financial service provider that offers a platform for funding education for people in need.

Portfolio highlights

• Buildpeer — Buildpeer is a project management software for construction fields. The company was founded by Mauricio Valdes in 2021 and is headquartered in Garza García, Nuevo Leon, Mexico.
• Hotelverse — Hotelverse allows customers search over hotels on their platform and book rooms as per their requirements.
• Savana — Electronic Health Records reuse, with Clinical Natural Language Processing.

Portfolio highlights

• ARX — Secure chips, onchain. Creators of @useburner @offlinecashco @kongiscash.
• Kamino — Building the next generation of credit infrastructure on Solana. NFA.
• Squads — Collaborative infrastructure for web3 native teams