Top 50 Cryptocurrency Startup Investors in Spain (July 2026)

Portfolio highlights

• TietAI — TietAI builds healthcare data interoperability infrastructure for hospitals, research networks and life sciences. The platform, Hydra, is split into two products. Hydra Connects is non-medical-device middleware for clinical data exchange across HL7v2, FHIR, DICOM, OMOP, X12 and CDA. Hydra Agentic is a high-risk AI system under the EU AI Act,designed for clinical agentic workflows.
• Tolemy Bio — Tolemy Bio develops AI-driven tools to design, optimize, and control cell culture processes for advanced therapies. The company focuses on precision-engineered, custom cell culture media for cell and gene therapies and biologics. Its platforms use artificial intelligence and machine learning to map how nutrients and signals influence cells. TolemyBio supports cell therapy innovators with data-driven media design and process control. Its solutions aim to improve critical quality attributes and manufacturability for advanced therapeutic products.
• Charms — Charms AI is an on‑chain mobile application focused on AI characters with persistent memory and user‑facing economies. The platform allows creators to build AI characters that can maintain long‑term conversational context and have their own wallets and tokenized assets, while users interact with, back, and trade around those characters. It sits atthe intersection of AI‑driven interaction, gaming‑style engagement, and blockchain‑based tokenization, with the overall design geared toward converting user attention and interaction into on‑chain economic flows.

Portfolio highlights

• Flextock — Discover efficient order fulfilment with Flextock. We streamline your inventory, orders, and shipping, ensuring accuracy and cost-effectiveness.
• OnSite — OnSite is a messaging and communication platform built specifically for construction and field‑service teams. It helps teams coordinate tasks, share updates, and manage project‑related information directly within a chat‑style interface. The platform also turns routine conversations into structured documentation to reduce manual admin work and keepproject records organized.
• Fly Media — Fly Media offers an AI-powered platform for automated video production and content adaptation driven by smart workflows. The platform helps creators and brands generate, edit, and localize media at scale, streamlining tasks like scene assembly, formatting, and repurposing across channels. Behind its “generated” media vision, the company maintains aseed-stage pitch room with a deck, business plan, and product videos available via its website.Fly Media emphasizes reducing manual overhead in content creation by applying AI to repetitive tasks and enabling teams to focus on high-level creative decisions.

Portfolio highlights

• DotOracle — DotOracle is a chainless decentralized network. They use a combination of the PBFT protocol and the elliptic curve multi-signature technique to enhance node communication and speed up node agreement. Their polka dot ecosystem by providing a decentralized oracle service to transfer information from the real world to polka dot in real-time.
• Vent Finance — The easiest way to research, apply, and purchase early crypto project tokens. Sign up and get started today.
• Zeitgeist PM — Zeitgeist PM is a blockchain tech to facilitate prediction markets and the futarchy form of governance.

Portfolio highlights

• Buildpeer — Buildpeer is a project management software for construction fields. The company was founded by Mauricio Valdes in 2021 and is headquartered in Garza García, Nuevo Leon, Mexico.
• Hotelverse — Hotelverse allows customers search over hotels on their platform and book rooms as per their requirements.
• Savana — Electronic Health Records reuse, with Clinical Natural Language Processing.

Portfolio highlights

• Autochek — Welcome To Autochek Group's Homepage. Read About The Company's Vision And Mission. Select A Country And Apply For Car Loans
• CINETPAY — CinetPay is a mobile money payment hub that federates mobile money payment methods in Africa.
• Franc — Franc is the easiest way to save & invest. Our app doesn’t require any investment knowledge & our friendly risk quiz helps us understand how much investment risk is right for you. Users can start investing in less than 2 minutes. There is no minimum requirement & no paperwork. It is a seamless digital experience end-to-end. A usersimply chooses a goal, selects an investment strategy, verifies their identity & makes a deposit. Each user is recommended a personalised investment strategy for each investment goal, combining money market & index tracking ETFs. Our helpful calculators assist clients with their budgeting, retirement & targeted savings needs. We also provide free access to our online academy & fun financial literacy quizzes.We know saving is hard & investing can be scary, which is why we create savings groups & challenges so that users can encourage one another. We also run weekly competitions where users can stand a chance to win a cash prize that will boost their investments.

Portfolio highlights

• Allawee — Allawee is a corporate credit card with a credit line to help you spend smarter. We give you high credit limits, attractive cashback rewards and advanced spend management tools.
• Raenest — Access Virtual Accounts, Invoicing, Multi-Currency Payouts, Auto Payroll, Accounting Integrations, and Virtual & Physical cards within minutes.
• Woodcore Inc — Woodcore is a Cloud Enabled Core Banking System for Banks, Micro Financial Institutions and Neo Banks primarily for emerging markets. We provide them with the Core banking system to digitise their existing process from using excel or any manual ways of offering banking service and then provide them with the merchant payment platform which allowsthem to be technology ready for integrations from third parties.

Portfolio highlights

• Flipflow — Flipflow is a SAAS company developing the most advanced price and ecommerce data monitoring BI software. We offer our customers accurate market data and a very powerfull and flexible BI platform and automation tools so they can maximize competitiveness, profitability and margins and take better business decisions.
• Kalipso — Kalipso automates regulatory compliance for financial institutions across Europe. AI-powered analysis of MiCAR, PSD2, CCD2, DORA & more. Live in 2 weeks.
• Centinel — Centinel plugs into your ERP and drafts the work that used to take hours - ready for your approval. It also applies the same accounting logic. It learns the G/L, chart structure and business rules to draft complete and audit-proof entries. It optimizes continuously adapting to the business rules.

Portfolio highlights

• ABSORA —
• Atrya — Atrya develops regulatory-compliant blockchain payments for international companies.
• Punto Health — AI-Powered, Personalised Support for Every Patient and Family

Portfolio highlights

• Tea-Fi — Tea-Fi is an all-in-one decentralized finance (DeFi) platform that turns complexity into opportunity.
• Finceptor — Become an early investor of Web3's top projects with over 250,000 other backers.
• web3intelligence — Build wealth and trust in the world of crypto with intelligent financial tools, data and infrastructure.

Portfolio highlights

• Simetrik — Automate repetitive data reconciliation processes without any coding knowledge
• Simetrik — Simetrik offer big data solutions for financial control and automation services for corporate companies.
• numia — numia (formerly Debmedia) is a B2B SaaS platform that helps industries manage customer journeys by seamlessly integrating online and offline experiences. By combining AI automation with human interaction, numia assists companies—including leading banks, insurance firms, telcos, healthcare providers, and retailers—to boost sales, optimize customerengagement, and enhance customer satisfaction.

Portfolio highlights

• Talstack — Talstack is an all-in-one platform for employee growth and development
• MAKA — MAKA is a community commerce platform for fashion and beauty, enabling everyone to discover their style, feel represented.
• Renda — At Renda, we are passionate about revolutionizing the logistics and mobility sectors with cutting-edge technology that enables businesses and operators to seamlessly scale in emerging markets.

Portfolio highlights

• BioSNARKS — ZK-proof for biotech and DeSci
• Myriad —
• Amnis Finance — Stake APT on the best liquid staking protocol on Aptos to receive daily rewards with an attractive APR of 3%.

Portfolio highlights

• Athos — The Athos mission is to help athletes train more effectively and reach their performance goals faster. Athos does this by bringing together the most relevant data and exercise science to deliver simple, actionable insights that allow coaches and athletes to get the most out of their training.
• Mason America, Inc. — Mason is the device innovation platform for product leaders who dare to deliver the next innovation in their field.
• Early is Good — Multi-omic diagnostics that analyze DNA, RNA, and Protein from a single sample for unprecedented cancer clarity.

Portfolio highlights

• Nestcoin — Nestcoin is a web3 application company that builds, operates, and invests in crypto-native products.
• Defy — Defy : India's first social crypto exchange - Buy, Sell & Trade Crypto instantly and easily with INR at the best prices
• Doorbell Health — Your front door to home health.

Portfolio highlights

• MediQuo — MediQuo is a hospital in your pocket, connecting patients and professionals for any health interaction. Healthcare today has 75% of unnecessary medical visits that could be taken in the distance, and the vast majority of health professionals are using messaging platforms such as WhatsApp to communicate with patients or other health professionals.MediQuo is a chat-based app specialised in health, GDPR and health data compliant, giving professionals time control, incorporating patient medical history and phone privacy. Allowing also video and audio communication. It is a place for discussion, appointments or medical consultation with your doctor or any new health professional. Also includes immediate 24/7 medical response and a network, for health information and professional discovery. We have done already 1M consultations and got 600k app downloads. Our Google Play Ratings are 4,6 (with 6k reviews). We are amongst the top health apps in Spain and Latam.
• Uxia — Uxia offers an AI-powered platform for rapid UX/UI user testing using synthetic users that imitate real-world behaviours without the need for human testers.
• Renty — Renty is the marketplace connecting people and stores around product rental.

Portfolio highlights

• Tazapay — Experience Tazapay's best-in-class global payment solutions for businesses. Our extensive network supports cards, local payment options, and bank transfers in over 173 countries, ensuring seamless collections, secure holding, and efficient payouts worldwide.
• DePay — DePay is an Argentina-based real-time payments infrastructure startup.
• The Giving Block — The Giving Block makes it easy for nonprofits to accept non-cash donations like crypto and stocks for 2,000+ nonprofits. The Giving Block is the largest platform that helps nonprofits accept crypto and stock donations. In 2022, it was acquired by Shift4, a publicly traded payments company.

Portfolio highlights

• STEM Cafe — STEMCafe by RVRB is a fun out of school learning centre for kids
• Juicyway — Juice is a developer of a payment network platform for cross-border business payments for businesses and individuals. It facilitates financial transactions between parties regardless of location to allow enterprises to participate in international trade and the exchange of goods and services.
• Lori Systems — Lori Systems is revolutionizing African logistics through innovative technology solutions. We connect shippers, transporters, and drivers to create efficient, reliable, and transparent supply chains across Africa.

Portfolio highlights

• Midi Health — Expert care for women 40+. Made for midlife. Delivered by experienced clinicians. Covered by insurance. Book a visit today.
• Rebels — Rebelstork was born to make Parenting Lighter. We are the largest tech-driven marketplace for baby gear in North America - diverting overstock and retailer returned baby gear away from landfills and into the homes of customers at a fraction of the retail price.
• Formulary Financial — Formulary Financial is a modern fund administrator that combines best-in-class talent and technology to deliver unparalleled partnership for GPs and LPs.

Portfolio highlights

• JuniGo — JuniGo is a financial technology company that provides a digital wallet and payment platform for micro, small, and medium enterprises.
• Takenos — Takenos provides the best way to get paid in LATAM for freelancers and contractors.
• SuperIntent —

Portfolio highlights

• XMTP — XMTP is a decentralized and quantum-resistant messaging protocol for builders.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.
• Superstate — Superstate is modernizing investing through tokenized financial products

Portfolio highlights

• Brass — Get started with a modern current account
• MarketForce — MarketForce connects Africa’s informal retail outlets and consumers directly to suppliers of consumer goods and financial services by digitizing orders, delivery, and payments with the aim of solving the last mile distribution challenge.
• ThankUCash — ThankUCash is a technology company powering rewards and loyalty for African banks and businesses. ThankUCash helps merchants grow revenue by connecting them to customers within and outside of their locations while retaining acquired customers using a data analytics-powered reward system where customers earn cash rewards for every transaction madeboth offline and online.

Portfolio highlights

• Depinsim — DepinSim is a blockchain-based eSIM platform that lets users access global mobile data and earn rewards.
• Superset —
• ZenChain — ZenChain is a Layer-1 blockchain focused on secure, EVM-compatible smart contracts and cross-chain interoperability.

Portfolio highlights

• Thndr — Thndr is a financial services company that operates an app-based investment platform.It comes with 0% commission, no account minimum, access to market data, easy account setup, and funding processes. Users can also get access to the latest news, market data, and other educational tools. Seif Amr established the company in 2020 in Cairo, AlQahirah, Egypt.
• Ezeebit — Ezeebit is a payment solutions provider that enables African merchants to accept cryptocurrency payments both in-store and online. The platform processes transactions quickly and automatically converts the cryptocurrency into stablecoins to eliminate volatility risk. Funds are then settled into the merchant's local currency account, typicallySouth African Rand (ZAR), on the next business day. The company offers multi-currency support for popular cryptocurrencies like Bitcoin and Ethereum and maintains compliance with financial regulatory bodies.
• Letly — Letly is developing an AI‑driven platform for the rental property market that automates tasks related to managing rental listings and tenant interactions. It aims to use intelligent agents to handle tasks such as scheduling viewings, responding to inquiries, and optimizing property management workflows. The platform is currently in a waitlistphase, signaling ongoing development and private access only.

Portfolio highlights

• SYNTHR — SYNTHR is redefining instant and slippage-free asset movement across chains
• Astarter — Astarter is a software firm that designs and offers financial services with a sustainable ecosystem.
• Flurry Finance — Flurry Finance is an IT service and consulting firm that offers decentralized protocol for easy earnings and stable coin holdings.

Portfolio highlights

• Rocket — Rocket is an on-chain prediction market platform enabling real-time price forecasts with continuous, accuracy-based rewards.
• Squads — Collaborative infrastructure for web3 native teams
• Legend. trade — Legend. trade is a crypto trading company by decentralized exchange.

Portfolio highlights

• Artela — Artela is an extensible L1 blockchain with parallel execution and modular VMs. With key innovation of EVM++, Artela enables modular, customizable, and scalable dApps.
• Diva — Diva Staking is an Ethereum Liquid Staking protocol powered by distributed validators and a set of permissionless node operators. Join our community and become part of Diva.
• CEBG Studio — CEBG Studio is a gaming studio.

Portfolio highlights

• DuelNow — DuelNow offers bookie-free sports betting. At DuelNow you can create crypto bets, set your odds, and win on your terms.
• Metagood — Tokenization as a Service for Modern Capital Markets
• Monochrome — Monochrome Corporation is a multi-investment, financial services group specialising in infrastructure projects within the bitcoin and crypto-asset landscape.

Portfolio highlights

• FLOORFY — Real estate software to create virtual tours. The new way to show your portfolio of properties from anywhere and at any time. Know it!
• Dost — Dost automates the process of incoming supplier invoices to help CFOs and Finance Managers of mid-size and large companies with a high volume of invoices to improve efficiency, accuracy in data entry and reduce time when processing incoming invoices by leveraging artificial intelligence (AI) and intelligent process automation (IPA).
• Food for Joe — Food for Joe is a pet food company.

Portfolio highlights

• Perion — Win Crypto Questing in AAA Games.
• Farmington State Bank — Do more with a Moonstone FDIC insured bank account and manage your non-traditional assets from the same place.
• Optim Finance — Optim Finance provides investment tools that optimize yield on digital assets. Their financial primitives enable users to rent ADA delegation rights to power novel use cases such as SPO loans, leverage into ISOs, and initial bonds.

Portfolio highlights

• Kash — Kash is a decentralized, AI-powered prediction market on social media where users trade on real-world events in real time.
• CrunchDAO — CrunchDAO uses the strength of Web3's collective intelligence to build a Trading Signal that generates profit whether the stock market is up or down.
• Kulipa — Kulipa provides the underlying infrastructure to settle global payments, manage stablecoin accounts, and issue cards - all through a unified, compliant stack. Grow revenue with debit cards. Boost acquisition with white-labelled accounts & cards. Scale faster with global payment products.

Portfolio highlights

• D3 — D3 - DNS Domains for Web3
• Share — Share XYZ is an information technology service provider
• Forta Protocol000 — Powered by the most advanced AI detection model, Forta Firewall integrates with protocols and rollups to prevent over 99% of hacks.

Portfolio highlights

• Ruka — We celebrate Black women and create hair products designed with real textures in mind.
• GingerControl — GingerControl is AI global trade compliance infrastructure. One AI automation system with multiple ways to access it.Trade compliance requires classifying products under the Harmonized Tariff Schedule, calculating layered duty obligations, and documenting every decision to meet CBP's reasonable care standard under 19 U.S.C. 1484. Most teamsdo this manually or with tools that store tariff codes but don't reason through classification. GingerControl automates the reasoning.Built for customs brokers, importers, exporters, freight forwarders, and the platforms connecting them: 3PLs, marketplaces, and ecommerce platforms.Core tools: - HS & HTS Classification Engine: applies GRI logic, references CROSS rulings, produces audit-ready reports - Tariff Calculator: full duty stack including MFN, Section 301, Section 232, reciprocal tariffs, and Chapter 99 - EAR/ECCN Classifier: export control classification for dual-use goods - Tariff Engineering: duty optimization through classification and sourcing analysis - Customs Entry Auditing: automated review of entry data against classification records - Customs AI & Clearance Automation: end-to-end customs processing - Tariff Briefing: daily policy change monitoring and reclassification alertsAccess points: - AI Trade Compliance Partner: AI co-pilot for classification, tariff analysis, and audit documentation - Ecommerce Trade API: embeds compliance intelligence into checkout, fulfillment, and cross-border workflows for 3PLs, marketplaces, and ecommerce platforms - Live AI Compliance Hub: five web-based tools at app.gingercontrol.com - AI Compliance Workspace: integrated platform for enterprise compliance teamsIntegration and scale: - REST API connections to SAP GTS, Oracle GTM, and NetSuite - Batch processing from 1K to 100K+ classifications per day - Multi-format input: PDF, images, spreadsheets, text descriptionsServices: - Custom AI system development - ERP integration consulting - Compliance workflow optimizationTry our tools at app.gingercontrol.com
• Round Finance — Round Finance is a fintech consulting firm specializing in digital financial services and funding rounds.

Portfolio highlights

• Qrem —
• Shapelets — Shapelets optimizes GenAI and data visualization with advanced vector databases and agile tools for data professionals
• Wagmi Venture Studio — Wagmi VS is creating transformative web3 experiences that democratize opportunity and ownership of the internet.

Portfolio highlights

• Criptan — Criptan is a cryptocurrency platform.

Portfolio highlights

• Atlys — Atlys is the world's leading visa platform with 99.5% on-time delivery for over 150 destinations.
• Atlas — Atlas builds cutting-edge generative 3D AI technology to enable the creation of assets & virtual worlds.
• Bluesky — Bluesky is a new social media platform.

Portfolio highlights

• Rep3 — Rep3 is a Web3 community management application. Rep3 uses gamification methods to assist lps encryption projects in managing communities, members, and contributions.
• Pimlico — Leverage Pimlico to get more users by unlocking the full potential of gas sponsorships.
• NiftyApes —

Portfolio highlights

• Oort — Oort is a Web3 data cloud that helps build and scale your data-driven business easier and faster with the most powerful Web3-native tools on the near-infinite decentralized cloud resources.
• Vengo AI — Vengo AI stands at the forefront of digital companionship and creator-driven marketplaces, recognized for its innovation with over $300,000 in credits and grants from tech leaders like Microsoft, Nvidia, OpenAI, Stripe, and more. Situated in an $850 billion market poised for significant growth by 2030, Vengo AI uniquely merges technology toredefine social interactions and AI leadership. This platform is a collaborative effort between Spinnr and Vengo AI, setting a new standard for next-gen brand-consumer engagement through real-time video and customizable AI personas. It revolutionizes brand engagement and offers celebrity AI personas for scalable, personalized fan experiences, all while requiring zero effort from the stars themselves. Vengo AI uniquely combines artificial intelligence capabilities with real-life human connections, offering a dual experience that sets it apart in the industry. This approach not only places Vengo AI at the vanguard of digital companionship but also firmly integrates creators into its economic model, enabling them to share in the platform's success and redefine the landscape of digital interaction and community-driven economic participation.
• Torus Robotics — Torus Robotics develops unmanned ground vehicles, robotics, and innovative powertrain technology for defense, aviation, automotive, and consumer applications.

Portfolio highlights

• Eonstarter — Eonstarter is an Initial DEX offering (IDO) launch platform that focuses on the Bitcoin BRC20 ecosystem and allows users to share innovative blockchain projects with communities ready to fund them.

Portfolio highlights

• GTE — GTE is a decentralized trading platform that offers end-to-end trading services.
• Hylo —
• Sprinter —

Portfolio highlights

• MetaVisa — MetaVisa is a Layer 3 Middleware Protocol that provides a metaverse credit system based on blockchain data. MetaVisa Protocol helps users to establish and display reliable on-chain identity & credit records.
• Hot Cross — Hot Cross is an extensive cross-chain and multi-chain infra and web3 application playground that enables blockchain teams and their communities to thrive. Hot Cross is a company and an ecosystem in and of itself, and its goals are towards allowing communities to flourish using its technologies, whether or not they know they are the ones buildingthem.
• Vee Finance — Bridge the gap between traditional banking and crypto Defi Earn fixed/flexible return on deposited assets

Portfolio highlights

• Flow48 — Flow48 is a platform that allows companies to access capital by providing revenue-based finance services.
• PumpBTC — PumpBTC is a liquid staking protocol that aims to help Bitcoin holders to stake their bitcoins and earn yield while bolstering the security.
• Zerobase — Zerobase is a real-time ZK prover network that prioritizes speed, decentralization, and regulatory compliance. It generates ZK proofs within hundreds of milliseconds and provides decentralized, quick consensus via its HUB ring-wake mechanism, allowing for large-scale commercial application.

Portfolio highlights

• KOA Biotech — Detecta enfermedades a tiempo y maximiza tus resultados.
• Niche Mobility — Niche developes electric propulsion systems for e-bicycles with integrated digital gearchange.
• UPTECH SENSING — UPTECH SENSING designs, manufactures, and operates monitoring systems based on fiber optic solutions.

Portfolio highlights

• Eonstarter — Eonstarter is an Initial DEX offering (IDO) launch platform that focuses on the Bitcoin BRC20 ecosystem and allows users to share innovative blockchain projects with communities ready to fund them.

Portfolio highlights

• Hannun — Hannun manufactures and designs rustic, industrial, and Nordic style furniture to turn houses into homes.
• Criptan — Criptan is a cryptocurrency platform.

Portfolio highlights

• Web3Auth — Web3Auth is simple, non-custodial auth infrastructure that enables Web3 wallets and applications to provide seamless user logins for both mainstream and native Web3 users.
• Project SEED — Project Seed is an one-stop blockchain gaming ecosystem that accelerates mass-adaption.
• Horizon Land — Horizon Land is the infrastructure platform that empowers builders to construct their own open and accessible virtual worlds; and to scale in a complete ecosystem of Games, Education, Entertainment, Social networks, …

Portfolio highlights

• Nestcoin — Nestcoin is a web3 application company that builds, operates, and invests in crypto-native products.
• Glip.gg — Mobile gaming studio
• PlayerScript AI, Inc. — Empowering creators to build games/game assets using Generative AI.

Portfolio highlights

• NF3 — NF3 is a community focused NFT swaps and finance market.
• Atani — Visit ESPN for live scores, highlights and sports news. Stream exclusive games on ESPN and play fantasy sports.
• yoloyolo — In order to match the top NFT IPS with leading brands and uncover growth opportunities and revenue models for both these brands and the NFT IP holders, Yoloyolo is developing new infrastructure.

Portfolio highlights

• LOScoin — LOScoin is a web3 gaming and social application based on telegram bot. LOScoin is committed to profoundly combining Web3's novel interactive experience with the passion of LOScoin's MEME community, creating a highly engaging, entertaining, and economically active DAO community, and providing users with a completely new gaming and socialexperience.
• Sapien — Sapien offers Data Labelling Services with RLHF to fine-tune your LLMs potential. Improve model performance with better data to improve outcomes. Consult us now!
• Pixion Games — Pixion Games is a studio focused on building competitive esports games for mobile device.

Portfolio highlights

• Demether — Demether is a DeFi protocol that works to enable zero-cost access to TVL for blockchains.
• Amnis Finance — Stake APT on the best liquid staking protocol on Aptos to receive daily rewards with an attractive APR of 9%.
• NXI — Nexus Interactive gives collective growth and accrued value to its ecosystem.

Portfolio highlights

• Monogoto — IoT Connectivity Management Platform: Monogoto Provides Global Cellular Connectivity & Private LTE Solutions As a Service. Click to Learn More
• Nozomi Networks — Nozomi Networks keeps operational technology cyber resilient with OT network and endpoint visibility, threat detection, and AI-powered analysis.
• Mitiga Solutions — Mitigating the risk from climate-driven perils to your business assets everywhere.