Top 50 Blockchain Startup Investors in Spain (July 2026)

Portfolio highlights

• Citring — Citring is a smart juicer to make orange juice automatically.
• Trak — Trak is a software tool for healthcare professional to provide AI-based tele-rehabilitation services like physiotherapy and others.
• Biotasmart —

Portfolio highlights

• Salicru — Salicru offers energy optimization and protection of technological equipment that causes incidences in the electrical supply.
• BRICKBRO — Currently, Brickbro is one of the leading real estate transactional platforms in the spanish market.
• ATTSU — ATTSU is a machinery manufacturing company that offers steam boilers and thermal oil boilers for industrial purposes.

Portfolio highlights

• TietAI — TietAI builds healthcare data interoperability infrastructure for hospitals, research networks and life sciences. The platform, Hydra, is split into two products. Hydra Connects is non-medical-device middleware for clinical data exchange across HL7v2, FHIR, DICOM, OMOP, X12 and CDA. Hydra Agentic is a high-risk AI system under the EU AI Act,designed for clinical agentic workflows.
• Tolemy Bio — Tolemy Bio develops AI-driven tools to design, optimize, and control cell culture processes for advanced therapies. The company focuses on precision-engineered, custom cell culture media for cell and gene therapies and biologics. Its platforms use artificial intelligence and machine learning to map how nutrients and signals influence cells. TolemyBio supports cell therapy innovators with data-driven media design and process control. Its solutions aim to improve critical quality attributes and manufacturability for advanced therapeutic products.
• Charms — Charms AI is an on‑chain mobile application focused on AI characters with persistent memory and user‑facing economies. The platform allows creators to build AI characters that can maintain long‑term conversational context and have their own wallets and tokenized assets, while users interact with, back, and trade around those characters. It sits atthe intersection of AI‑driven interaction, gaming‑style engagement, and blockchain‑based tokenization, with the overall design geared toward converting user attention and interaction into on‑chain economic flows.

Portfolio highlights

• UMNAI — UMNAI's neuro-symbolic AI learns, explains and enforces policy in real time, with built-in governance. Intelligence you can trust. Decisions you can defend.
• Skarbe — Skarbe has officially wound down operations as of April 2026. Thank you for being part of our story.
• STAMP — STAMP redefines Tax-Free in Europe. Instant VAT exemption for travelers. More sales, transparency, and control for merchants.

Portfolio highlights

• Qrem —
• Shapelets — Shapelets optimizes GenAI and data visualization with advanced vector databases and agile tools for data professionals
• Wagmi Venture Studio — Wagmi VS is creating transformative web3 experiences that democratize opportunity and ownership of the internet.

Portfolio highlights

• DotOracle — DotOracle is a chainless decentralized network. They use a combination of the PBFT protocol and the elliptic curve multi-signature technique to enhance node communication and speed up node agreement. Their polka dot ecosystem by providing a decentralized oracle service to transfer information from the real world to polka dot in real-time.
• Vent Finance — The easiest way to research, apply, and purchase early crypto project tokens. Sign up and get started today.
• Zeitgeist PM — Zeitgeist PM is a blockchain tech to facilitate prediction markets and the futarchy form of governance.

Portfolio highlights

• Buildpeer — Buildpeer is a project management software for construction fields. The company was founded by Mauricio Valdes in 2021 and is headquartered in Garza García, Nuevo Leon, Mexico.
• Hotelverse — Hotelverse allows customers search over hotels on their platform and book rooms as per their requirements.
• Savana — Electronic Health Records reuse, with Clinical Natural Language Processing.

Portfolio highlights

• BEONx — Beonprice is one of the Travel Tech companies in Spain, committed to leading the future of revenue strategy. Agility, innovation and organization are the engines of the brand, with the aim of offering profitable innovation and being part of the DNA of each of its customers. Beonprice has developed HQI™, the only index in the hotel market thatmeasures the integral quality of a hotel in order to understand the competitive position and price elasticity of the demand in the market. Beonprice has more than 2,000 customers in more than 30 countries, its RMS is successfully used by growing hotel chains such as Petit Palace, HM Resorts, Dreamplace, Hospes, Palafox, Grupo Velas, Viaggio and many more.
• Articul8 — The Domain-Specific GenAI Platform, Purpose-Built for Your Data and Mission
• Flora — Flora Fertility is dedicated to empowering the next generation of parents by putting the control of reproductive health outcomes back where they belongs—in your hands. It aims to revolutionize how women's health and family building are approached, making fertility care more accessible, transparent, and personalized. By reimagining thefinancial and medical aspects of family planning, we help you navigate the journey to parenthood with greater confidence, ease, and support, ensuring that your fertility choices align with your personal goals and circumstances.

Portfolio highlights

• Tea-Fi — Tea-Fi is an all-in-one decentralized finance (DeFi) platform that turns complexity into opportunity.
• Finceptor — Become an early investor of Web3's top projects with over 250,000 other backers.
• web3intelligence — Build wealth and trust in the world of crypto with intelligent financial tools, data and infrastructure.

Portfolio highlights

• Rauda AI — Rauda is an artificial intelligence platform specialized in automating customer service with the best customer experience. Take a quantum leap in productivity, reduce costs and improve customer satisfaction with the power of generative artificial intelligence.
• Aino — AI-powered site analysis for real estate professionals. Generate feasibility studies with quantified metrics, maps, cost estimates, and zoning insights in minutes, no GIS or coding required.
• Orbital Paradigm —

Portfolio highlights

• RepScan — RepScan is an eliminate the negative that the Internet says about you. Rapid negative reputation detection and removal technology.
• YPLASMA — YPlasma, an INTA spin-off, develops plasma actuators for ionic flow control, enabling advancements in Energy and Electronics.
• Pack2Earth — Pack2Earth, S.L. is a company that specializes in developing new, sustainable materials for the food sector and other industries.

Portfolio highlights

• Flipflow — Flipflow is a SAAS company developing the most advanced price and ecommerce data monitoring BI software. We offer our customers accurate market data and a very powerfull and flexible BI platform and automation tools so they can maximize competitiveness, profitability and margins and take better business decisions.
• Kalipso — Kalipso automates regulatory compliance for financial institutions across Europe. AI-powered analysis of MiCAR, PSD2, CCD2, DORA & more. Live in 2 weeks.
• Centinel — Centinel plugs into your ERP and drafts the work that used to take hours - ready for your approval. It also applies the same accounting logic. It learns the G/L, chart structure and business rules to draft complete and audit-proof entries. It optimizes continuously adapting to the business rules.

Portfolio highlights

• Energiot — Energiot specialized engineering service in energy harvesting, self-powered devices, wireless sensor networks.
• DYNAMICS VR — Dynamics VR provides rehab software for clinics to tackle musculoskeletal pain and movement impairments caused by brain trauma.
• DARWIN Biomed — Biomedical Engineering

Portfolio highlights

• Xoople — Xoople operates as an earth intelligence company. Xoople powers the next generation of Earth data intelligence to achieve a systematic understanding of physical changes on the Earth’s surface.
• Orga AI — Organ AI creates generative artificial intelligence that will help people. Its headquarters is located in Palma De Mallorca, Islas Baleares, Spain.
• Golden Owl —

Portfolio highlights

• Mento Labs — Mento Labs is a decentralized EVM platform for launching and managing multi-currency stable assets.
• Learn.xyz — Learn.xyz’s is a mixture of Duolingo and Wikipedia, powered by AI, creating bite-sized “Curiosities” which feature slides and a quiz, in mere seconds just from taking in a user’s question. Find the app on iOS and Android.
• Thrive Protocol — Thrive Protocol's vision is to maximize value creation for all people and communities.

Portfolio highlights

• Credbull — Credbull manages on-chain private credit funds that provide vital financing solutions to creditworthy small and medium-sized enterprises (SMEs).
• Ink Finance — Ink Finance is the scalability solution for web3 DAOs, protocols and asset managers, enabling them to customize asset management and governance frameworks through a no-code interface, to effectively establish on-chain credit and financial competence. Ink Finance allows a one-stop and frictionless solution for organized financial activities, with scalability and customizability.
• Velvet Capital — Trade any crypto onchain - spot and perpetuals across 7 chains with AI-powered routing. Non-custodial DeFi trading terminal + AI trading bot. 100K+ traders.

Portfolio highlights

• Zeemcoin — Great prices on a large selection of domains. Find the pefect domain for your new startup.

Portfolio highlights

• MetaMall — Metamall will offer a unique virtual reality experience on the blockchain, allowing users to build, explore, and trade.
• Playermon — Playermoon is an NFT Game where anyone can explore and battle and earn NFTs.
• Vent Finance — The easiest way to research, apply, and purchase early crypto project tokens. Sign up and get started today.

Portfolio highlights

• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.

Portfolio highlights

• NuLink — NuLink combines best practices with best-of-breed security solutions to provide privacy-preserving technology with enterprise level security for decentralized applications
• COTI AI Agents — COTI AI Agents is an AI Agent platform on the COTI network that focuses on privacy and ease of use. Users can launch, train, and trade AI agents with just one click. Co-own agents to earn revenue share while enjoying personalized tools, fun interactions, and rewards.COTI AI Agents is the first grantee of MomentumX Accelerator - The #1 acceleratorfor startups exploring Web3 privacy, backed by COTI network & Poolz.
• Velvet Capital — Trade any crypto onchain - spot and perpetuals across 7 chains with AI-powered routing. Non-custodial DeFi trading terminal + AI trading bot. 100K+ traders.

Portfolio highlights

• Solak — Solak is an AI browser and DeFi platform that is transforming the digital world.
• GPU.Net — Interact with AI agents and autonomous systems on GPU.net. Chat, generate images, videos, and more with decentralized AI.
• OpenStamp — Features SRC20 & Stamps Marketplace, Minting Service, Launchpad, and an Explorer for SRC20 & Stamps asset tracking.

Portfolio highlights

• Banger — Banger is a blockchain-powered gaming platform that provides its users with an array of earning possibilities. Banger was founded in 2019 and was headquartered in Madrid, Spain.

Portfolio highlights

• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.

Portfolio highlights

• TucanPay — TucanPay is a money transfer platform that sends money between continents.
• Biotasmart —
• DARWIN Biomed — Biomedical Engineering

Portfolio highlights

• Vidext — We turn text into videos in more than 40 languages. Increase your impact, reach and engagement. Decrease your effort, budget and headaches.
• TaxDown — TaxDown has revolutionized tax advice by being lone of the pioneers in digital service that lets users file income tax returns easily. It claims to guarantee the taxpayers the desired results. As this company is the collaborator of the Tax Agency, taxpayers can present their income statements on their own platform. The digital and automaticsolution maximizes savings.
• Banktrack — Banktrack provides All the bank movements by Email, WhatsApp, or your favorite channel.

Portfolio highlights

• Splitfy — Splitfy is the perfect app to collect money from your plans Group.
• Viterbit — Viterbit is a technology start-up that offers a Recruitment and Selection Software (ATS). Just what your company needs to go one step further with the talent it hires. The greatest strength organizations have are the people who work in them, so our team is committed to helping you attract the talent you need.
• Agroptima — Agroptima is a farmer-centric mobile-based farm management software that makes farms more profitable and easy to manage.We power farmers with software and data that lets them easily manage their farms from their smartphone and increase their profitability. Agroptima’s goal is to automate data collection by integrating its software with sensorsand other sources of vital data to farmers.We're building the future of agriculture. Challenged? Join our team!

Portfolio highlights

• Simetrik — Automate repetitive data reconciliation processes without any coding knowledge
• Simetrik — Simetrik offer big data solutions for financial control and automation services for corporate companies.
• numia — numia (formerly Debmedia) is a B2B SaaS platform that helps industries manage customer journeys by seamlessly integrating online and offline experiences. By combining AI automation with human interaction, numia assists companies—including leading banks, insurance firms, telcos, healthcare providers, and retailers—to boost sales, optimize customerengagement, and enhance customer satisfaction.

Portfolio highlights

• Fermah — Fermah can generate proofs for any instance in which ZK is used. Fermah is credibly neutral and architected to support all proof systems. This includes zkVMs, zkEVMs, Groth16, and all other proof systems. It is optimized for cheap, fast, and reliable ZK proof generation.
• Mythik — Mythik operates as an entertainment company with a vision to bring Eastern mythology, history and folktales.
• NovaNet — NovaNet offers local verifiable computing and privacy protection applications, including AI, decentralized Internet of Things (DePIN), and games.

Portfolio highlights

• 1DOC3 — 1doc3 is a e-health platform that connects 490 million of Spanish speaking people with licensed and trusted doctors. Users find personalized answers to their health related questions. Doctors build their online reputation, find new patients and create the biggest health related questions and answers curated database in Spanish. The Platform isavailable via web, App, SMS and USSD, allowing the entire population to have access to a Doctor no matter where they are, or even if they don't have internet access.
• Unmanned Life — Unmanned Life is the leading software platform for seamless orchestration of autonomous robotics. It is changing the way autonomous robotics is being deployed by large corporations thanks to its autonomy-as-a-service orchestration platform powered by AI and 5G. Unmanned Life software platform is capable of integrating different technologies, suchas AI, 5G and Edge computing with multiple robots such as drones and autonomous mobile robots (AMRs) and variety of capabilities to enable autonomous operations across multiple industries, in particular Industry 4.0 and Smart Cities.
• YBVR — YBVR provides high-quality video VR streaming experiences: Immersive, interactive, and enriched, Live, and VoD.

Portfolio highlights

• Walken —
• Solana — Solana is the high performance network powering internet capital markets, payments, and crypto applications. Fast. Decentralized. Scalable. Energy efficient. Solana can power thousands of transactions per second.
• TrueNorth — Crypto's first AI discovery engine

Portfolio highlights

• Argo — Argo is a transit technology and services company that provides an integrated public transportation system, combining electric vehicles, intelligent routing software, and operational management to offer on-demand transit services. Its products and services include smart routing technology, EV transit vehicles, and mobile app-based ride matching forcommunities.
• Belo — Crypto for everyone, everyday
• Sidekick — Expertly-managed portfolios for the modern investor

Portfolio highlights

• Hydraverse — Hydraverse is a metaverse dragon fighting game developer, focusing on the development of a PVP dragon fighting game software.
• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.
• Vee Finance — Bridge the gap between traditional banking and crypto Defi Earn fixed/flexible return on deposited assets

Portfolio highlights

• LuxQuanta — Quantum Key Distribution or Quantum Cryptography provides long-term and future-proof data protection.
• Tolemy Bio — Tolemy Bio develops AI-driven tools to design, optimize, and control cell culture processes for advanced therapies. The company focuses on precision-engineered, custom cell culture media for cell and gene therapies and biologics. Its platforms use artificial intelligence and machine learning to map how nutrients and signals influence cells. TolemyBio supports cell therapy innovators with data-driven media design and process control. Its solutions aim to improve critical quality attributes and manufacturability for advanced therapeutic products.
• Axiomatic AI — Axiomatic AI is a startup that focuses on building verifiable artificial intelligence for complex science.

Portfolio highlights

• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.
• 8 Securities — 8 Securities offered mobile-only investing, a robo-advisory service, a social trading platform, and zero-commission brokerage. Through the platform, members will be able to follow the investment portfolios of top-performing members of the community and learn what they are buying, selling, and holding. They will also see where their own performanceranks.

Portfolio highlights

• Faith Tribe — Faith Tribe is a open- source fashion design platform that focuses on NFT minting, P2P transactions.
• Tren Finance — Tren Finance: a secure DeFi liquidity protocol offering seamless asset swaps, yield opportunities, and cross-chain compatibility through automated smart contracts, redefining liquidity for users and institutions.
• BLIFE Protocol — BLIFE Protocol's objective is to promote growth and development of Web3 on Bitcoin.

Portfolio highlights

• Runa — Runa provides solutions to increase conversions and maximize profits in real-time on online merchants' Websites. In 2008, more than $21 billion was spent on online marketing to drive traffic to online merchant Websites with mechanisms such as display ads, search optimization, lead generation, and affiliate marketing. However, conversion ratesof visitors to actual sales on the Website averaged only 2-3%. Over 97% of Website visitors dropped off without making a purchase. Runa allows online merchants to more than double the conversion rate of visitors. A one percentage point increase in conversions from visitors to sales among all the existing online merchants is equivalent to them spending approximately an additional $7 billion on online advertising at current efficiencies.
• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.

Portfolio highlights

• Sogni AI — Unleash creativity with the Sogni Supernet: a purpose-built DePIN protocol for Creative AI. Empowering Creative AI apps with unmatched speed and scale.
• Bondex — Join Bondex, a Web3 network with 4M+ users. Monetize connections, build your reputation, and earn $BDXN rewards. Advance your career or discover top talent now.
• Folks Finance — Folks Finance is a permissionless DeFi lending platform where users can lend and borrow crypto across chains, access loans, and manage digital assets in one unified liquidity protocol.

Portfolio highlights

• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.
• Infinity Arena — The place to connect players who love tactical card games or have passionate about collecting valuable and rare NFT cards.
• Ancient Kingdom — Ancient Kingdom is the first ancient martial arts game on the blockchain platform, pioneering the realization of real-time games on the blockchain platform.

Portfolio highlights

• Oumla — Secure, scalable blockchain infrastructure for businesses, enterprises, and governments to manage digital assets with ease and compliance.
• E36 Knots — E36 Knots build decentralized web3 services with the goal of empowering developers and users
• Forg3t Protocol — Forg3t Protocol provides provable AI unlearning infrastructure for enterprises. It enables verification and auditing of sensitive data removal from AI models. This ensures strong regulatory compliance. Built for secure, transparent AI data management.

Portfolio highlights

• Banger — Banger is a blockchain-powered gaming platform that provides its users with an array of earning possibilities. Banger was founded in 2019 and was headquartered in Madrid, Spain.

Portfolio highlights

• Barbara — Barbara is the Cybersecure Industrial Edge Platform that enables companies to connect, deploy and scale gateways and edge applications in a few clicks
• Minoryx Therapeutics — Minoryx is focused on the discovery and development of novel treatments for severe, orphan diseases of the central nervous system with high unmet medical need.
• iPronics — iPronics develops the innovative concepts of general-purpose integrated programmable photonic systems.

Portfolio highlights

• TACMIND — Tacmind is an AI platform that helps companies understand how AI models perceive, describe, and recommend their brand. It analyzes how large language models and other AI technologies speak about a brand, detecting tone, emotion, and narrative. Tacmind provides insights that allow companies to see their brand's presence and reputation inAI-driven environments, benchmark against competitors, and optimize their brand assets and messages specifically for how AI systems view them. This helps companies influence and improve the narrative AI models generate about their brand to better control brand perception and increase visibility in AI-assisted searches and recommendations. Tacmind’s tools give companies a strategic advantage in the evolving landscape where AI plays a significant role in shaping consumer decisions and brand discovery.​
• Apartool — housing supplier with accommodation for staff
• Ezra AI Labs — The company emerged from stealth in early 2025, with founder Ophir Samson.

Portfolio highlights

• Internxt — Here at Internxt, we're helping shape an Internet that truly respects you. Our first service, Internxt Drive, is a free & fully private cloud storage service and is part of our disruptive cloud infrastructure. Distributed, Trustless. Switch for free.

Portfolio highlights

• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• BullPerks — BullPerks is a community of like-minded individuals who want to leverage their power and invest together in the best projects on equal terms with VCs.
• Faith Tribe — Faith Tribe is a open- source fashion design platform that focuses on NFT minting, P2P transactions.

Portfolio highlights

• RepScan — RepScan is an eliminate the negative that the Internet says about you. Rapid negative reputation detection and removal technology.
• Kimera Technologies — Kimera develops software solutions to understand visual content, extract its useful data and transform it into accessible information.
• Lookiero Outfittery Group — Check out all the roles at LOOKIERO OUTFITTERY GROUP. Get to know the team, see our offices, learn about our values, and discover the benefits of working at LOOKIERO OUTFITTERY GROUP

Portfolio highlights

• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.
• AAG Ventures — AAG Ventures is the IT business behind AAG, one of the fastest-growing Play-To-Earn guilds in the industry.

Portfolio highlights

• VIVLA — We make exclusive second homes in top European locations accessible to everyone. Buy shares of your home without having to buy the whole property.
• Remuner — Say goodbye to spreadsheets. Remuner is the sales compensation software that automate your commissions and drive performance.
• Internxt — Here at Internxt, we're helping shape an Internet that truly respects you. Our first service, Internxt Drive, is a free & fully private cloud storage service and is part of our disruptive cloud infrastructure. Distributed, Trustless. Switch for free.

Portfolio highlights

• MediQuo — MediQuo is a hospital in your pocket, connecting patients and professionals for any health interaction. Healthcare today has 75% of unnecessary medical visits that could be taken in the distance, and the vast majority of health professionals are using messaging platforms such as WhatsApp to communicate with patients or other health professionals.MediQuo is a chat-based app specialised in health, GDPR and health data compliant, giving professionals time control, incorporating patient medical history and phone privacy. Allowing also video and audio communication. It is a place for discussion, appointments or medical consultation with your doctor or any new health professional. Also includes immediate 24/7 medical response and a network, for health information and professional discovery. We have done already 1M consultations and got 600k app downloads. Our Google Play Ratings are 4,6 (with 6k reviews). We are amongst the top health apps in Spain and Latam.
• Uxia — Uxia offers an AI-powered platform for rapid UX/UI user testing using synthetic users that imitate real-world behaviours without the need for human testers.
• Renty — Renty is the marketplace connecting people and stores around product rental.

Portfolio highlights

• Peeba — Peeba is a curated online wholesale marketplace that transform the way local retailers in Asia shop for their stores.
• BRICKBRO — Currently, Brickbro is one of the leading real estate transactional platforms in the spanish market.
• Our Happy Company — Our Happy Company Turn your original content into NFT Vibe in just seconds. Have complete freedom to decide how many editions to make, set initial sell price and your NFT debut date, all from the comfort of your phone.