Top 50 VC Funds & Investors in Panama (June 2026)

Portfolio highlights

• The Arena — A next gen SocialFi app redefining how creators connect, engage, and monetize their content.
• Joystream — Joystream is a block chain-based, decentralized video platform.
• Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

Portfolio highlights

• Aark — Trade crypto perpetuals with up to 1000x leverage, zero gas fees, and an industry-low 0.01% trading fee. Earn payback on losses with VIP rewards. RWA & altcoin perps on Arbitrum. Backed by OKX Ventures.
• Ta-da — We collect, annotate, and label audio, image, video, and text data to power your AI training. From voice and facial recognition to biometrics and object detection, we build tailored datasets for your needs.
• Itheum — As we enter the web3 and metaverse era; Itheum unlocks data silos and generates new value for your data.

Portfolio highlights

• Cogni — Cogni is a new digital banking platform that brings you curated brands and experiences while helping manage your spend.
• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• Snackclub — Learn more about play to earn games

Portfolio highlights

• myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
• Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• Bluwhale — Unlock Web3 Wallet Potential with AI Insights. Supercharge Your Business Growth
• Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
• BluWhale — BluWhale's mission is to leverage AI and ML to allow game developers to focus on ways to improve the game rather than wrangling and making sense of astronomical amounts of data. BluWhale's smart automation will do the heavy lifting usually reserved for data analysts and data scientists all in the background, and surface actionable insight

Portfolio highlights

• SnakeLite — Snake Lite is a classic arcade snake game with a competitive edge and offers offline and online play. It is designed for smooth controls and fast performance.
• Sophon — Sophon brings the benefits of blockchain to everyday entertainment without the complexity. Discover games, social experiences, and applications that put users first, not technology.
• Eizper Chain — Eizper Chain is a blockchain action online multiplayer role-playing game that celebrates adventure and arena battle.

Portfolio highlights

• GENCY AI — Gency AI is a Web3 platform for privacy-focused, verifiable digital ads using encrypted data and proof-based tracking.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.
• Interstate — Interstate is an Ethereum pre-confirmation protocol. It aims to make Ethereum transactions near-instant and allow applications to self-order while maintaining full composability with L1.

Portfolio highlights

• EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
• Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• AEON — AEON is a crypto payment framework designed for AI-driven and real-world transactions. It supports omni-chain payments across ecosystems like EVM, SVM, and TON, enabling seamless cross-chain usage. Its solutions include AI-powered payments, Web3 online and mobile payments, QR/contactless acceptance, and swap pay, all designed to simplifyadoption for users and merchants.
• AlchemyNFT — AlchemyNFT is a non-fungible token (NFT) service.
• Unitas —

Portfolio highlights

• Metatheory — Metatheory Inc. is an interactive technology and entertainment company building Web3 games, interactive content, social experiences, and other community-driven adventures. Metatheory’s mission is to inspire imagination by connecting people worldwide through immersive worlds built on cross-generational IP.
• Pagos Solutions — Get real-time payment data detecting issues, trends, and opportunities plus intelligent payment solutions for optimizing payment performance.
• Spaceport Technologies — Accelerating the growth of the next digital economy

Portfolio highlights

• 0G — The First Decentralized AI Operating System
• DNABLOCK — We enable Web3 creator communities to design and mint NFT collections of truly custom photorealistic 3D avatars, environments and cinema-quality animated content with no code or animation knowledge.
• Ignite Tournaments — Ready to take your mobile games to the next level? Join Ignite Tournaments and compete in real money esports tournaments. Download our app now and win big!

Portfolio highlights

• MSafe — MSafe offers the most secure, decentralized, scalable Web3 non-custodial, multi-signature solution built on Move, ideal for dApp developers to use for treasury management, token management, smart contract development, blockchain protocol admin control, live on Aptos
• Momentum — Momentum is a move central liquidity engine with multi-sig treasury management, token vesting, and liquidity provisioning.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• PERL.eco — The Planetary Ecosystem Registration Ledger will be a dedicated blockchain for real-world ecological assets through tokenizing carbon credits and biodiversity, NFTs and decentralised (DeFi) rewards.
• Meter.io — Meter.io is a base layer hybrid consensus protocol built to address the volatility, scaling and interoperability problems in the existing cryptocurrencies.
• Injective — Explore Injective: the high-performance blockchain powering decentralized finance, governance, and next-gen Web3 apps with unmatched speed and scale.

Portfolio highlights

• BBy — BBy connects nursing mothers with couples who can't produce or do not produce enough breast milk to feed their child
• Careerist — Careerist is the connecting bridge between people without tech or coding background and the U.S. tech industry. We quickly train and apply our students for simple well-paid jobs like software testing, while helping them grow into more advanced roles.
• Legistify — Legistify offers AI-powered legal operations software to streamline workflows, manage contracts, track legal cases and improve productivity for enterprise legal teams

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• Flappy Bird — Flappy Bird Foundation is to uphold the Flappy Bird intellectual property and further the Flappy Bird heritage. The Foundation accurately restores our vintage and nostalgic gameplay while adding new features to give back to the worldwide fan base that started the craze.
• Community Labs — Community Labs is a software development company and venture studio focused on accelerating developer tools, use cases, and adoption of Arweave and AO.

Portfolio highlights

• Persona AI — Persona AI builds industrial humanoid robots designed for real world worksites, performing skilled, dangerous, and physically demanding tasks.
• Eezee — Singapore’s first & largest industrial marketplace that connects local suppliers to corporate clients, leveraging technology to help both parties make informed decisions.The company offers a secure platform for buyers and sellers to transact.Our aim is to improve the efficiency of business to business (B2B) transactions. We do this byensuring that the process of selecting and purchasing your supplies becomes quicker, more convenient and transparent. We support local suppliers in establishing their presence online, enabling them to be discovered by corporate organisations.
• Petal Surgical — Petal is a surgical technology company pioneering incisionless surgery through Acoustic Sculpting, a proprietary form of boiling histotripsy. Our platform uses focused sound waves to precisely destroy harmful tissue without cuts, heat, or toxicity offering gentler alternative to traditional surgery.

Portfolio highlights

• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Xion Finance — Xion Finance is the easiest way to start earning a passive income on your crypto. Earn interest, shop products or yield farm with a novel one click to DeFi protocol. Get Started Today!
• QANplatform [QAN blockchain platform] — QANplatform is the quantum-resistant Layer 1 hybrid blockchain where developers can code web3 solutions in any language on top of the QAN blockchain platform.

Portfolio highlights

• Dmail — Dmail Network is a decentralized mailbox that provides a safe and private environment for users' communication, storage, tokens, and NFTs. The company was founded by Mittal S. and Lucas L. in 2021.
• OMNIA Protocol — OMNIA Protocol offers a secure and private infrastructure for accessing blockchain technology. It provides high availability RPC endpoints for Ethereum, ensuring users can connect to the blockchain without being traced or monitored. The company focuses on delivering a compliant environment for handling personal data, including blockchain addressesand transactional information. OMNIA Protocol aims to democratize access to blockchain infrastructure, challenging the current concentration of this access among a few corporations. It supports various blockchains, including Bitcoin, Binance, Avalanche, Polygon, Arbitrum, and Optimism, through its platform, offering secure Arbitrum RPC Nodes features.
• Cumulus Encrypted Storage System (CESS) — CESS revolutionizes AI, DeSci, RWA, Enterprise, and more with secure, transparent, and traceable data solutions. Delivering AI computing and data infrastructure, CESS enables data privacy and sovereignty with a focus on AI Agent applications and frameworks.

Portfolio highlights

• Biconomy — Blockchain transactions made simple. Enable Gasless meta-transactions, instant cross-chain transfers, easy layer 2 onboarding & zero failed transactions
• ZAP — ZAP offers a reputation-based token distribution protocol that supports fair rewards for user contributions within the Blast ecosystem. It enables users to participate in various projects through missions and seamless investment options. Additionally, ZAP is expanding its services to other blockchains and developing tools to simplify access toventure-capital-backed projects.
• Velvet Capital — Trade any crypto onchain - spot and perpetuals across 7 chains with AI-powered routing. Non-custodial DeFi trading terminal + AI trading bot. 100K+ traders.

Portfolio highlights

• Hybrid — Hybrid is a fintech company that offers a decentralized central AI tool with Web3's ecosystem of AI experts, agents, and data.
• Ajuna Network — Ajuna Network is a decentralized ecosystem for gamers and creators.
• Liquorice — Liquorice is a developer of a DeFi protocol that combines one-sided loan pools with a MEV-free trading engine.

Portfolio highlights

• Wicrypt — Wicrypt is a dynamic organization that consistently allows its users to get paid by sharing their Wi-Fi.
• Gamic — Gamic is a community communication/collaboration app for gamers, creators, and web3 enthusiasts.The platform combines the advantages of blockchain technology with the conventional web2 community setup, creating a seamless environment where users can interact and enjoy the benefits of web3 advancements. This simplifies the process for web2communities to access and leverage the latest blockchain technology innovations, eliminating the need to navigate across various platforms.Today, the user experience is poor for online communities trying to engage with Web3 products and services because users are required to jump across different platforms. Sharing, trading, or managing Web3 assets on most traditional communication and social apps is hard. Addressing this is crucial because Web3 access means financial freedom and opportunity for many all around the world, especially in Africa. Gamic’s central mission is to encourage blockchain adoption as a means to improve the socio-economic opportunities available to global communities. We enable users to communicate and operate in the same place, with increased security and better monetisation opportunities.
• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.

Portfolio highlights

• XOCIETY — The XOCIETY metaverse is being developed by a well-established team of over 50 developers with decades of experience in the tech and web2 gaming fields.
• The FishVerse — FishVerse combines GameFi, AI, and blockchain technology, allowing players to fish in a dynamic open environment from their own homes.
• NXI — Nexus Interactive gives collective growth and accrued value to its ecosystem.

Portfolio highlights

• PayCaddy — Launch a card issuing program without the hassle.
• Crew.work — All-in-one recruiting platform that helps you hire the A players your moonshot mission needs.
• InspectMind — InspectMind AI is a platform to redefine inspections with artificial intelligence that significantly reduces report preparation time by incorporating multimedia inputs into comprehensive reports.

Portfolio highlights

• BullPerks — BullPerks is a community of like-minded individuals who want to leverage their power and invest together in the best projects on equal terms with VCs.
• Hashflow — Tight spreads. Zero slippage. MEV-resistant.
• Joystream — Joystream is a block chain-based, decentralized video platform.

Portfolio highlights

• Munily — Munily, a proptech software, Is redefining security and administration in residential communities by centralizing all communications.
• Momint — Momint is the Web3 investment platform of the future. The safest and easiest to use NFT marketplace in the world. Discover the real-world potential of NFTs.
• PropertyScout — PropertyScout is a proptech startup that builds an end-to-end rental and sale platform for owners, agents, buyers, and tenants. The startup is connecting over 1,800 agents and agencies with buyers, renters, and owners, servicing thousands of satisfied customers every month. PropertyScout leverages its database of more than 200,000 properties, itstechnology platform, and its centralized operations to digitize and automate 90% of the real estate transaction. This frees up agents’ time to professionally and efficiently communicate with buyers, renters, owners and co-agents to deliver outstanding service and close transactions faster. Providing a transparent and trusted experience, PropertyScout has quickly become the favorite go-to place for buying, selling, and renting real estate in Thailand, as proven by hundreds of five-star reviews.

Portfolio highlights

• Blockfolio — Blockfolio offers mobile portfolio tracking and management for the cryptocurrency and blockchain industry.Blockfolio is the network for mobile cryptocurrency portfolio tracking and management. Millions of people trust Blockfolio to stay connected to the pulse of the industry through market data, news, and direct updates from leaders of top cryptoprojects. Blockfolio is committed to providing free access to our users and token team partners.
• Edge — Get Edge to manage all of your crypto assets. The most secure way to buy, store and trade crypto under your control Accounts Created + 0 MM Assets Supported + 0 Languages Supported 0 Countries Supported 0 Private, Secure & Easy to Use Cutting edge security, user privacy, and ease of use are at the
• Solus — Simplified, Low Risk & Engaging Derivatives for All

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• Euclid Protocol — Euclid creates a chain agnostic liquidity layer that allows any application to integrate and swap against an efficient market to provide the best user experience for users.

Portfolio highlights

• Caden — Caden is the world's first Zero-Party Data platform. We allow users to own and control their own personal data, make money off it, and share it with trusted consumer brands, while maintaining their privacy.
• AnthologyAI — AnthologyAI is the breakthrough Artificial Intelligence Consumer Insights & Predictions Platform with billions of real-time data sourced directly and ethically from consumers. Access previously unavailable levels of intelligence about retail spending, geolocation, media consumption, travel, ride sharing and more — in realtime, at scale.
• Vero Technologies — Vero Technologies is a Financial Services based company.

Portfolio highlights

• MoonPay — MoonPay offers a fast and simple way to buy and sell cryptocurrencies. Buy crypto with credit card, bank transfers or Apple Pay today.
• Milano Vice — Milano Vice is building a new virtual food brand by working with professional kitchens to prepare and deliver delicious pizzas to home.
• Kapital — Kapital empowers SMBs with a tech-banking platform giving visibility and control of their treasury, and their employees

Portfolio highlights

• Aire — The income assessment platform that leverages first-party data. Access real-time confidence in the stated income of any consumer.
• Questflow — Questflow Labs seeking to give customers with an all-in-one solution for user intent perception and distribution, AI agentic workflow automation, and human-AI cooperation. Questflow Labs is pioneering a novel approach to decentralized AI agentic workflow.
• Flare — Flare equips your team to shut down cybercrime before it escalates. Detect, prioritize, and remediate external cyber threats with automated Threat Exposure Management.

Portfolio highlights

• OpenPad AI — OpenPad - The 1st AI Decentralized Launchpad
• Stabble — stabble is a protocol revolutionizing liquidity pools by introducing protocol-managed and arbitrage pools. This allows stabble to tackle critical inefficiencies prevalent within Solana's decentralized exchanges.
• AI Cross Matrix — AI Cross Matrix is a DeFi platform that makes the crypto economy simple by streamlining the exchange process with useful solutions.

Portfolio highlights

• Outer Ring — Enter a vast sci-fi universe where five species fight for dominance. Explore, craft, conquer and own your destiny in Outer Ring MMO.
• Infinity Arena — The place to connect players who love tactical card games or have passionate about collecting valuable and rare NFT cards.
• Ancient Kingdom — Ancient Kingdom is the first ancient martial arts game on the blockchain platform, pioneering the realization of real-time games on the blockchain platform.

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• GAIB — GAIB is the economic foundation for the future of artificial intelligence and computers. GAIB is a crypto-AI platform under development that tokenize GPUs, making AI computing—the processing power required to train and run AI models—more accessible.
• Yala — Yala operates a multi-token system and unlocks a thriving and interconnected DeFi ecosystem on Bitcoin​.

Portfolio highlights

• Prime Trust — Prime Trust powers innovation in the digital economy by providing fintech and digital asset innovators with financial infrastructure. Our API is customizable whether you're building a crypto exchange or expanding your business with digital assets.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Datagram — Datagram is an AI-driven, decentralized infrastructure platform operating as a DePIN baselayer. The company provides a live, scalable node network for launching custom DePIN networks and real-world decentralized applications, with cost savings over traditional cloud providers.
• Ooga Booga — Multichain Liquidity Aggregator
• Accountable — Accountable is the new standard for real-time financial verification. Prove assets and liabilities privately, powered by the Data Verification Network (DVN).

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• RedStone — RedStone delivers frequently updated, reliable and diverse data for your dApp and smart contracts.

Portfolio highlights

• Splyce Finance — dETF protocol. Permissionless, on-chain index- and yield ETFs.

Portfolio highlights

• BRKT — Join the fun on BRKT! Make predictions on sports, pop culture, and more!
• Gata — Gata uses data technology to develop superintelligence and to ensure its alignment with human objectives.
• Algebra.Finance — Algebra.Finance is the Financial Services.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Anoma — A sovereign, proof-of-stake blockchain protocol that enables private, asset-agnostic cash and private bartering among any number of parties.
• Keplr — Introducing the first, and leading, IBC-enabled wallet for Cosmos and beyond
• Datachain — Datachain is a tech company that revolutionizes blockchain interoperability and stablecoin settlement. we aim to make it possible for the world to interact as one network, making it easier to use a variety of services.

Portfolio highlights

• Kuri — Kuri is a healthtech company that uses AI for revenue cycle management services at hospitals, laboratories, and clinics.
• Yuno — A fast checkout that integrates your company to the payments and fraud ecosystem.
• Bia Energy — Bia Energy engages in energy marketing.

Portfolio highlights

• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Elusiv — Elusiv offers compliance in mind with next-generation privacy solutions for a better Web3.
• TipLink — TipLink helps send crypto with a link. Someone with crypto can create a account and send that link to anyone over any platform. It’s like buying a gift card, connect the client's crypto wallet of choice and create a account by depositing how much they want to send.
• Blueberry Protocol — Access premium DeFi opportunities, tokenized yield strategies, and comprehensive tools for the Hyperevm onchain ecosystem.

Portfolio highlights

• Rise Of Defenders — Rise of Defenders is a very interesting Metaverse NFT game, you can use your creativity and tactical thinking to become an excellent player and receive extremely attractive rewards.
• Amyl Therapeutics — Amyl Therapeutics is a preclinical stage biotechnology company. Amyl Therapeutics uses a novel mechanism to bind to the amyloid fold of toxic protein aggregates of various types, including antibody light chain (AL) or transthyretin (TTR) aggregates, which accumulate in peripheral organs to cause systemic amyloidosis diseases, but also amyloid-β(Aβ), Tau, and α-synuclein aggregates, which accumulate in the brain to cause Alzheimer's and Parkinson's diseases.

Portfolio highlights

• Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
• Stems Labs — community and platform for collaborative creativity
• MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Eywa — Founded in 2021, EYWA helps Web3 projects scale up by enabling them to operate, get listed, and traded on all connected blockchain networks with a single liquidity pool. Additionally, EYWA provides a truly decentralized data protocol for secure messaging.In partnership with Curve Finance, one of the largest decentralized exchanges, EYWA isintroducing a new paradigm of non-algorithmic cross-chain assets aimed at solving the problem of liquidity fragmentation. Their cross-chain protocol stands out as the most decentralized solution in the market.- Received 6 grants from biggest L1/L2 blockchain networks including NEAR Foundation, Aurora, Harmony One, Algorand, Boba Network, and others - Winning hackathons: Ethglobal Marketmake, Polygon’s BUIDL IT hackathon, Metis hackathon
• TG DAO 3.0 — TG DAO 3.0 is TG Ecosystem's launchpad for investing in conventional and crypto startups. All launchpad investors are considered to be co-owners and take part in the decision-making process for the launchpad functions. TG DAO 3.0 is a new crowdfunding blockchain launchpad on the TG Ecosystem that combines decentralized and centralizedinvesting, attracts mechanisms, and provides comprehensive support for startups.
• GoFungibles — GoFungibles is a cross-chain state-of-the-art NFT marketplace equipped with all the existing features of conventional NFT marketplaces but augmented with DeFi and gamified components.

Portfolio highlights

• Zabo — Zabo is an API for connecting to any crypto exchange, wallet, protocol or account. Sign up for access to free API keys at Zabo.com
• Ballet — Ballet Crypto is a companion mobile app, which enables sending of cryptocurrency, checking market value and activating additional currencies. The use of the mobile app is completely optional, as you do not need it to receive and store your cryptocurrency safely.
• Ceramic Network — Ceramic Network is a provider of protocols for decentralized and composable data applications. The network decentralizes application databases, making data universally composable and reusable across applications. It consists of three core parts: a highly-scalable, decentralized infrastructure for data availability and consensus, a marketplace ofcommunity-created data models, and a suite of standard APIs for storing, updating, and retrieving data from those models.

Portfolio highlights

• Altcoinist — Altcoinist is an interoperable community gating infrastructure that transforms private communities into vibrant on-chain economies by bringing cutting-edge token gating, community staking pools, and enabling new revenue sources for creators and communities.

Portfolio highlights

• Sidus Heroes — gaming company
• Zombie Worldz — Zombie World Z is a metaverse combining VR on the BSC, upgraded and developed based on a successful and established Zombie Idle Defense.
• CryptoVsZombie — CryptoVsZombie is the ultimate crypto tower defence in which players are required to multitask in both offensive and defensive modes.