Top 50 Software Startup Investors in Cayman Islands (October 2026)

Portfolio highlights

• ETHGas — The Realtime primitive that accelerates Ethereum over 100x
• Burstverse — Burstverse, a Web3 AI business, is at the vanguard of the DeFai revolution, offering an AI-powered decentralized financial platform that allows users to automate and control their cryptocurrency operations using natural language. Burstverse is changing the way consumers engage with and benefit from decentralized financial ecosystems by mergingcutting-edge AI and DeFi flexibility.
• Limitless Labs — Trade on future outcomes with Limitless, a prediction market for crypto prices, sports matches, politics, and major world events.

Portfolio highlights

• Ruvo — Cacao is a fintech platform that allows Brazilians to receive, store, spend, and withdraw USD instantly.
• Coop Records — Coop Records investing in next generation of music enabled by Web3.
• Limitless Labs — Trade on future outcomes with Limitless, a prediction market for crypto prices, sports matches, politics, and major world events.

Portfolio highlights

• EarnOS — EarnOS is the fully remote company that provides Global Ad & Payments Platform powered by Web3.
• KOR Protocol — KOR Protocol is a decentralized intellectual property (IP) infrastructure designed to empower creators, protect rights, and enable seamless collaboration and monetization of IP assets across various industries, including music, film, TV, gaming, and art. Backed by notable entities like Animoca Brands, Republic, Niantic, Sfermion, Solana, andprominent creators such as Black Mirror, Disclosure, deadmau5, and Richie Hawtin, KOR leverages blockchain, AI, and DeFi to offer a transparent, efficient, and scalable environment for IP expansion.
• Freehand — AI Teams for Complex Spend Management

Portfolio highlights

• Raven — Raven is a proprietary high-frequency algorithmic trading firm specializing in CeFi market making and DeFi liquidity provision.
• Jeeves Inc. — Pay for anything, anywhere, in your local currency. No fees. No interest. No personal guarantees. Mobile-first, built with your team in mind.
• Catchback Cards — Catchback Cards offers a platform for buying, selling, storing, and auctioning collectibles with pack opening and card-backed loan services.

Portfolio highlights

• BULK Trade — One Exchange Infinite Markets
• Pave Bank — The world's first multi-asset and programmable bank
• Nova Markets — Decide what lists next on @HyperliquidX and earn from every listing, forever.

Portfolio highlights

• Deblock — Better than your bank: IBAN, Visa card, instant SEPA transfers, 4% a year, and a self-custody wallet for your crypto.
• Harbor — Future Proof Finance
• Dakota Ridge — Stablecoin infrastructure that enables global money movement.

Portfolio highlights

• Orthogonal — Giving AI agents the tools they need.
• World Foundation — World is the real human network. A new standard of trust on the internet.
• Solana Company — Building the Preeminent Solana Treasury $HSDT

Portfolio highlights

• Cowboy Snake — Cowboy Snake is the TvT play-to-earn game inspired by snake on the blockchain. Cowboy Snake is a product of OrenCT Ltd.
• Formless — Formless enables gamers, NFT enthusiasts and digital collectors to find their favourite game while helping games find their targeted fans.
• Clear Protocol — Clear Protocol, Inc. is a healthcare IT company. Our product, Clear Protocol, is Software-as-a-service for hospitals, clinics, and medical offices.

Portfolio highlights

• Jeeves Inc. — Pay for anything, anywhere, in your local currency. No fees. No interest. No personal guarantees. Mobile-first, built with your team in mind.
• Velocity — Velocity provides a unified platform for efficiently moving and managing funds across both traditional banks and blockchains.
• Silicon Data — Revolutionize compute markets through unparalleled data transparency, financial product innovation and market intelligence

Portfolio highlights

• ARX — Secure chips, onchain. Creators of @useburner @offlinecashco @kongiscash.
• Kamino — Building the next generation of credit infrastructure on Solana. NFA.
• Squads — Collaborative infrastructure for web3 native teams

Portfolio highlights

• NG.CASH — NG.CASH is a digital bank designed to help the new generations (ages 12 to 30) achieve financial independence. It lets users take charge of their money through solutions like PIX (Brazil’s instant-payment system), prepaid and virtual cards, allowance management, and now credit products tailored for young adults. As a financial hub, NG.CASH is builtto grow with its clients, boosting financial literacy and supporting them at every stage of life.
• TRM Labs — Next Generation Blockchain Intelligence | Monitor, Investigate, and Mitigate Crypto Fraud and Financial Crime
• Tare — Tare uses AI and tokenization to change the entire credit lifecycle.

Portfolio highlights

• Atum — Atum is the open payments network that coordinates those systems.
• Tenor Labs — Tenor helps people borrow and lend money at a fixed rate without needing permission.
• Hello Clever — Connect every rail and understand every payment. Unify your payment infrastructure with Clever AI to instantly turn transaction data into measurable growth.

Portfolio highlights

• Entravel — Market leading hotel distribution API & room mapping. Agentic interface for AI agents. Turnkey hotel booking white labels for businesses.
• Solana — Solana is the high performance network powering internet capital markets, payments, and crypto applications. Fast. Decentralized. Scalable. Energy efficient. Solana can power thousands of transactions per second.
• TrueNorth — The first Agentic Brokerage - build your own professional trading desk

Portfolio highlights

• TBook — The first embedded RWA liquidity layer that brings institutional-grade tokenized yield into user-facing apps
• Catapult — Market agnostic, hyper-volatile charts. Ride 100x in minutes. https://t.co/kMSFE0RKBI
• Euclid Protocol — The Unified Liquidity Layer for DeFi | Euclid Protocol is a cross-chain DeFi infrastructure enabling efficient token swaps, liquidity aggregation, and optimized routing across 50+ blockchains on Evm, Cosmos and Solana.

Portfolio highlights

• Hook — Hook provides an NFT-native options protocol that enables active traders to earn more with less. For active traders, options allow them to earn multiples of buying the floor for the best trades.
• Atlas — Atlas builds cutting-edge generative 3D AI technology to enable the creation of assets & virtual worlds.
• Particle — Particle: Diversified Restaking for Leverage Trading and Interest Rate Swap.

Portfolio highlights

• Cambrian — The financial intelligence layer for agents & institutions. Cambrian's API helps you make the best financial decisions onchain. Testnet waitlist @ https://t.co/eohvz17ALp
• Superpower — the economy layer where agents make money
• Cluster Protocol — Cluster Protocol is the co-ordination layer for AI agents, a carnot engine fueling the AI economy making sure the AI developers are monetized for their AI models and users get an unified seamless experience to build that next AI app/ agent within a virtual disposable environment facilitating the creation of modular, self-evolving AI agents.

Portfolio highlights

• rio.ai — rio.ai provides WhatsApp-based delivery of medicines, personal care items, baby products, and pet supplies.
• Pilot Protocol — Network OS for AI Agents
• Arctus Aerospace — We build unmanned airplanes for zero infrastructure earth observation. We fly at 45,000 feet for 24 hours at a go.

Portfolio highlights

• Snag — Snag operates an AI-powered housing marketplace and rental discovery platform.
• Ellis — Ellis connects and reconciles portfolio, fund, and investor data across the systems you already use. Every number traceable. Run every fund from one trusted view.
• Steven.com — The operating system for the creator economy. Connecting creators to resources, platforms, community and technology where trust shifts to individuals.

Portfolio highlights

• ether.fi — EtherFi is a non-custodial decentralized ETH staking method that distributes staking to node operators in exchange for rewards.
• Azuro — Powerful tooling, oracle & liquidity solutions for any EVM predictions & gaming ecosystem
• QED Protocol — A trustless, scalable, decentralized compute protocol for a fairer internet focused on user privacy and platform transparency.

Portfolio highlights

• Cyclops.io — Cyclops is the only crypto and stablecoin platform exclusively for payments companies. Cyclops enables payment service providers to accept crypto, do stablecoin settlement, and manage digital assets with enterprise-grade security. We provide PSPs, Card Networks, Acquirers, PayFacs and otherws with compliant crypto solutions without building in-house. Cyclops is chain agnostic, supporting Bitcoin, Ethereum, USDC, USDT, and multi-chain stablecoin settlement. White-label and turnkey offerings.
• Félix — Félix is ​​a chat-based platform that enables Latinos in the US to send money abroad. We combine Blockchain and Artificial Intelligence to disrupt how remittances are done today and build the future of cross-border payments.
• Birdai Labs — Birdai operates at the base of the chain, measures where value leaks between an order and its fill, and is built to return it to the people who create the order flow.

Portfolio highlights

• 3Commas — 3Commas develops a crypto-asset management tool for tracking investments and exchanges in a unified platform. It provides access to a unified dashboard as the central hub for trading and portfolio management execution.
• Fuel Labs — At Fuel, we are building the fastest execution layer for the modular blockchain stack.
• Optim Finance — Optim Finance provides investment tools that optimize yield on digital assets. Their financial primitives enable users to rent ADA delegation rights to power novel use cases such as SPO loans, leverage into ISOs, and initial bonds.

Portfolio highlights

• TurboFlow — Trading, made simple. Everyone gets a seat at TurboFlow.
• DePay — DePay is an Argentina-based real-time payments infrastructure startup.
• Limited — Secure your treasury and scale your business globally with a truly self-custodial account that only you control. No banks. No middlemen.

Portfolio highlights

• tanX.fi — Reliable, self custodial and high performance liquidity network for traders, institutions and exchanges.
• Brine.fi — The best onchain spot trading crypto exchange
• Payman AI, Inc — We deploy AI that executes real banking transactions - payments, transfers, account analysis - through voice or text, on your existing rails. Full visibility, configurable controls, complete audit trails.

Portfolio highlights

• IOTrader — Decentralized Trading Platform,Precision Futures Trading Built for Modern Traders Trade crypto, forex, commodities and more with low fees,
• Tomoland — Tomoland is a social gaming platform where users create avatars, worlds, and multiplayer experiences.
• Midas — Structured Products, Onchain.

Portfolio highlights

• Blitzy — You Describe It, We Build It
• Satflow — Satflow aims to improve Bitcoin DEXs, enhance decentralization, and address issues like lack of advanced order types, high-speed data, and liquidity pools.
• Build on Bitcoin — BOB (Build on Bitcoin) is the first Bitcoin L2 with full EVM compatibility

Portfolio highlights

• Higgsfield — The ultimate AI-powered camera control for creators by creators
• Firelight — Firelight is a DeFi protocol that allows XRP holders can stake tokens and help cover risks on DeFi platforms.
• Alkemya Luxembourg — Alkemya Luxembourg is an international high tech metals firm specializing in sourcing and distributing rare earth oxides, titanium, and nickel wire, that are increasingly important to R&D and manufacturing companies in semiconductor, aerospace, and other high technology industries.

Portfolio highlights

• onaji — We research, develop and maintain data pipelines, models, and integrations for decentralized applications, discovery algorithms, and fraud reduction systems.
• Othentic — Othentic provides builders with the most intuitive way to spin up a modular blockchain on top of EigenLayer
• Limitless Labs — Trade on future outcomes with Limitless, a prediction market for crypto prices, sports matches, politics, and major world events.

Portfolio highlights

• ether.fi — EtherFi is a non-custodial decentralized ETH staking method that distributes staking to node operators in exchange for rewards.
• Usual — Usual Labs operates as a decentralized finance(DeFi) protocol.
• LayerZero Labs — An omnichain interoperability protocol. LayerZero enables the realization of cross-chain applications with a low level communication primitive.

Portfolio highlights

• Levl — Levl's infrastructure makes stablecoin-powered payments accessible, compliant, and operationally seamless. Supporting USD, EUR, GBP Named Accounts and liqudity into emerging markets.
• Raven — Raven is a proprietary high-frequency algorithmic trading firm specializing in CeFi market making and DeFi liquidity provision.
• OpenTrade — OpenTrade providers web3 treasurers, institutions, and accredited investors access to on-chain structured financial products backed by investment grade RWAs.

Portfolio highlights

• X10 — X10 operates as a hybrid crypto exchange provider.
• Squads — Collaborative infrastructure for web3 native teams
• Trace Finance — Trace Finance enables secure and swift connections between businesses and their customers through payments and automatic transaction reconciliations on a large scale, promoting integrity and efficiency.

Portfolio highlights

• Oh — The OpenAI of the spicy content industry, combining consumer platforms (@ohchatai | @ohdotfun) with infrastructure (https://t.co/BMwDSzAg14)
• Paxos Labs — Blockchain infrastructure for enterprises. Regulated by the OCC in the US, FIN-FSA in the EU, and MAS in Singapore. For support, visit https://t.co/qmOCfQa262
• Zcash Open Development Lab — Builders of the Zcash protocol and flagship Zcash wallet, Zodl @zodl_app. We envision a world without mass financial surveillance.

Portfolio highlights

• Travix — Travix is an on-chain, agentic omnibroker and AI-powered quant terminal built for trading perpetual contracts across global markets.
• FinTax — FinTax is a financial technology platform that provides cryptocurrency accounting, global tax solutions, and AI infrastructure for digital asset institutions.
• OpenCheck — OpenCheck AI is a decentralized, AI-powered authentication and luxury marketplace platform designed to secure and verify the multi-billion-dollar global collectibles market.

Portfolio highlights

• Alfred — Alfred is a software startup focused on accelerating the research and development (R&D) timelines for robotics, autonomous vehicles, and advanced hardware manufacturing.
• Mach Industries — Delivering decentralized warfare capabilities to guarantee the defense of freedom.
• The Horowitz Andreessen Academy — The Academy provides a unique path for the next generation of IT leaders coming out of high school.

Portfolio highlights

• Almanak — Almanak is a decentralized finance (DeFi) smart agent platform that harnesses the power of artificial intelligence to automate, optimize, and intelligently manage a wide range of DeFi investment strategies. It enables users to create and deploy automated DeFi trading and risk-management strategies through coordinated AI agents. It provides anenvironment where AI handles strategy coding, backtesting across thousands of Monte Carlo simulations, optimization, risk monitoring, deployment via non-custodial Safe-based multisig accounts, and real-time performance monitoring with alerting capabilities. The platform supports seamless interaction with multiple blockchains and protocols via an LLM-powered interface.Almanak targets active DeFi participants, developers building financial applications, investment professionals, and users seeking automated portfolio insights. It emphasizes enhanced automation, continuous strategy execution, and adaptive automation driven by emerging AI techniques to respond to evolving market conditions.
• Megapot — The $1,000,000 lottery with the world's best odds | 100,000+ prizes paid Builders: https://t.co/uDN54A9EtY Enterprise: @prizerail Backed by @dragonfly @cbventures
• Tenbin Labs — TradFi liquidity with DeFi utility. Global markets, tokenized on-chain.

Portfolio highlights

• Squads — Collaborative infrastructure for web3 native teams
• Nova Markets — Decide what lists next on @HyperliquidX and earn from every listing, forever.
• Physical Superintelligence — Physical Superintelligence develops physical superintelligence systems that use AI-driven research to study physics, engineer physical systems, and explore new physical laws. Its approach combines human scientists with virtual physicists that conduct autonomous research campaigns covering hypothesis development, verification, experimentation,engineering, and deployment. The company focuses initially on the physical infrastructure underlying AI, including energy, materials, computation, sensing, and manufacturing.

Portfolio highlights

• MNX — The AI Exchange
• Venice — Private & Unrestricted AI
• Limited — Secure your treasury and scale your business globally with a truly self-custodial account that only you control. No banks. No middlemen.

Portfolio highlights

• Obita — Obita provides enterprise-grade borderless payment infrastructure for fiat and compliant stablecoins, supporting global collections, payouts, and treasury operations.
• Hemi Labs — Hemi (https://hemi.xyz) is a modular protocol that integrates Bitcoin and Ethereum to amplify and extend the core capabilities of the two leading blockchain networks. This offers a novel perspective on blockchain interoperability and scaling by approaching Bitcoin and Ethereum as components of a single supernetwork. The result providessecurity that exceeds that of Bitcoin (“superfinality”) and new levels of blockchain programmability, portability, and potential. Hemi was co-founded by Jeff Garzik (former Bitcoin core developer) and Max Sanchez (inventor of the Proof-of-Proof consensus protocol), and is surrounded by a team of renowned blockchain engineers, strategic partners and investors.
• Questflow — AI Finance Agent for Outsized Returns. An AI finance agent that lets you invest alongside top investors across markets.

Portfolio highlights

• Oh — The OpenAI of the spicy content industry, combining consumer platforms (@ohchatai | @ohdotfun) with infrastructure (https://t.co/BMwDSzAg14)
• Chance Studios — Every Collection Starts With A Chance
• Chance Studios — Every Collection Starts With A Chance

Portfolio highlights

• Bloom — Moved to @bloomsocial
• Lite Strategy — MEI Pharma, Inc. (Nasdaq: MEIP) is a San Diego-based oncology company focused on the clinical development of novel therapies for cancer. The Company’s clinical development pipeline includes lead drug candidate Pracinostat, a potential best-in-class, oral histone deacetylase (HDAC) inhibitor. Pracinostat has been tested in more than 150 patients inmultiple Phase I and exploratory Phase II clinical trials, including advanced hematologic malignancies such as myelodysplastic syndrome, acute myeloid leukemia and myelofibrosis. The Company expects to initiate a randomized Phase II trial of Pracinostat in combination with standard-of-care in at least one hematologic malignancy toward the middle of 2013. In addition, MEI Pharma is developing two drug candidates derived from its isoflavone-based technology platform, ME-143 and ME-344. Results from a Phase I trial of intravenous ME-143 in heavily treated patients with solid refractory tumors were presented at the American Society of Clinical Oncology Annual Meeting in June 2012. A Phase I clinical trial of intravenous ME-344 in patients with solid refractory tumors is ongoing.
• VersiFi — VersiFi is a prime services platform. It provides full-service prime brokerage solutions.

Portfolio highlights

• RISE Chain — RISE is a next-generation Ethereum Layer 2 blockchain designed to redefine blockchain performance by delivering near-instant transaction confirmations at unprecedented scale, all while upholding Ethereum’s foundational principle of decentralization
• Limitless Labs — Trade on future outcomes with Limitless, a prediction market for crypto prices, sports matches, politics, and major world events.
• BIO Protocol — Biotech's new financial layer.

Portfolio highlights

• Cenoa — Cenoa - The smartest way to get paid globally!
• Chainlink — Chainlink is the most widely used oracle network for powering hybrid smart contracts, enabling any blockchain to securely access off-chain data & computations.
• Hue — Hue is a software as a service platform that finds and incorporates real video evaluations into the marketing channels and websites of e-commerce companies.Hue enables businesses and retailers to incorporate TikTok-style shoppable films on their e-commerce websites, giving customers confidence to add to cart.

Portfolio highlights

• Hemi Labs — Hemi (https://hemi.xyz) is a modular protocol that integrates Bitcoin and Ethereum to amplify and extend the core capabilities of the two leading blockchain networks. This offers a novel perspective on blockchain interoperability and scaling by approaching Bitcoin and Ethereum as components of a single supernetwork. The result providessecurity that exceeds that of Bitcoin (“superfinality”) and new levels of blockchain programmability, portability, and potential. Hemi was co-founded by Jeff Garzik (former Bitcoin core developer) and Max Sanchez (inventor of the Proof-of-Proof consensus protocol), and is surrounded by a team of renowned blockchain engineers, strategic partners and investors.
• Prodigy.Fi — earn yield on crypto and tokenized assets. set your price, earn while you wait. @ethereum @base @HyperliquidX
• Rails — Experience unparalleled speed and efficiency with Rails, your go-to platform for lightning-fast crypto perpetuals trading.

Portfolio highlights

• Pally — Pally is an AI personal assistant you text. Use it on iMessage, Android RCS, or Telegram for email, calendar, reminders, research, and errands.
• twyne — Twyne operates a decentralized finance (DeFi) credit delegation protocol that routes underutilized borrowing capacity from collateral depositors directly to active market borrowers. The infrastructure functions as an intermediary aggregation layer on top of established lending markets to optimize credit distribution and maximize capital efficiency.
• TrueNorth — The first Agentic Brokerage - build your own professional trading desk

Portfolio highlights

• Redpill AI — Access 200+ AI models with privacy-first infrastructure. Private models in GPU TEE, OpenAI-compatible API, zero data retention.
• Rivet.cloud (Formerly OpenRelay) —
• Karmine Corp — Karmine Corp is an esports organization that offers merchandise and competes in games like league of legends, trackmania, and others.

Portfolio highlights

• Sticky: AI Game Maker + Gaming Platform — Sticky is a mobile social and gaming superapp with an AI Game Maker at its center. Using AI, Sticky lets creators make professional-quality games on their phones or in their browsers in a few minutes without touching a line of code. Creators can publish on the Sticky platform and earn money. They can also integrate social features, collectibles,in-game-purchases, leaderboards, and more to their games, as well as submit their games to game jams. Sticky members can play thousands of games and make friends, chatting in clubs, streaming, competing in tournaments, and more.

Portfolio highlights

• Kaizan — Kaizan is a Client Intelligence Platform for Client Success teams to retain and grow revenue
• Baanx Group — Replacing Banking With Technology - Our technology enables self-custody transactions, allowing users to buy, spend, and borrow directly against digital assets securely and effortlessly.
• Build on Bitcoin — BOB (Build on Bitcoin) is the first Bitcoin L2 with full EVM compatibility

Portfolio highlights

• Soter Insure — Reliable insurance for the digital asset ecosystem.
• Ethereum Institutional — Accelerating institutional adoption of Ethereum
• Digital Prime Technologies — Full-Service Institutional-Grade Prime Brokerage for Digital Asset Management. DLCC offers full-service Prime Brokerage solutions for digital assets. Our all-in-one user interface leverages both API and Saas product offerings to connect clients with a growing network of liquidity providers to transact, borrow, and lend digital assets, and managecollateral. Our product suite also offers traditional Prime Brokerage services, such as consultation and capital introduction.

Portfolio highlights

• Tria — Threely is onboarding billions onto Web3 with universal identities. Threely addresses are blockchain-agnostic identities that can be used across Web3 as a profile, chain-agnostic payment endpoints, logins, zkKYCs, and more. Threely is doing the crucial work of helping the top blockchain protocols, wallets, and dApps cast a wider net to onboard abroader part of the internet to Web3.
• Self Protocol — Self is spearheading a secure, human-first internet by allowing users to verify their identities while maintaining their privacy. Self Protocol is an identity and proof-of-humanity solution that uses zero-knowledge technology to confirm personhood and distinctive traits, like age and nationality, without revealing private information.
• Multiplier — Multiplier helps institutional investors research stocks and manage their portfolios. We're live with six hedge funds, and our users spend 4+ hours a day in the platform.Investors who try "nearly every tool on the market," to quote a client of ours, "wind up with an unwieldy collection of fragmented point solutions."Those who focus on building a great setup with general agents are instead "signing up for a full-time job." So we deploy a platform called Multiplier that unifies structured data, unstructured data, AI work, human work, and tacit firm knowledge in one secure, governed, customized application.Our first vertical: independent equity funds with $250M-$5B of assets. They know AI is essential for staying relevant, but they don't have the time or talent to figure out what to do about it. But once we deploy Multiplier––"We used to spend 80% of our time gathering information and 20% of our time acting on it," said one customer. "Multiplier has flipped those percentages."

Portfolio highlights

• InsideDesk — Reduce AR days, boost collections, and streamline billing operations with InsideDesk's centralized revenue cycle management platform.
• CWX — CLOUDWERX provides elite engineering resources to accelerate your business.
• Lightworks — Lightworks is a Canadian consulting company that focuses on enterprise AI infrastructure and control systems. The company works with the biggest and most regulated companies in the world to plan, manage, and safeguard AI-powered systems.

Portfolio highlights

• Fluxco — One spec in, competitive bids from 150+ global OEMs back in days. Procurement, leasing, service and warranty from one accountable partner.
• Sequen — Sequen is user behavior by design.
• FINN — At finn our mission is to make mobility fun and sustainable: We help everyone who loves driving their own car but refuses the struggle, commitment and intransparent costs associated with car ownership. We achieve this by offering all-inclusive, immediately available, monthly car-subscriptions. Best thing, yet: While you drive we plant trees asevery journey is CO2 compensated.