Top 50 Enterprise Startup Investors in Cayman Islands in May 2026

Portfolio highlights

• 3Box — 3Box Labs is a Web3 studio that creates software to advance a more open, safe, and composable Web3. We're hiring!
• Zerion — Zerion is an investing app that enables anyone, anywhere in the world, to access a suite of new financial products and services built on the backbone of decentralized finance (DeFi). Simple, user-centered design is combined with a powerful tech stack that aggregates across every major decentralized exchange, offering users a single point of entryfor managing their digital assets with ease. Zerion is non-custodial, which means users never delegate their funds to the platform. This agile approach mitigates centralization risk and has allowed Zerion to operate globally since inception.
• Magic — We've onboarded 50 million people to the world's leading apps. We're trusted by over 200,000 developers. We're Magic.

Portfolio highlights

• zkMe — zkMe delivers reusable zero-knowledge KYC, zkKYA (Know Your Agent) and zkKYC for the agentic economy. Verify the human principal behind every AI agent.
• Mocaverse — Mocaverse is the Animoca Brands membership NFT collection of 8,888 unique beings: The Mocas. Join the Mocas in the realms to Learn, Play, Do Good, and Build together as we champion our Web3 values!
• Legend of Arcadia — Legend of Arcadia is a mobile card-based RPG inspired by Kingdom Hearts, leveraging blockchain technology for immersive gameplay. Players can engage in real-time PvP modes, trade highly composable NFTs, and earn rewards through strategic gameplay.

Portfolio highlights

• Polybase — Payy helps businesses and developers move, store, and spend stablecoins without exposing every transaction to the public internet.
• Randamu — Revolutionizing Real-World Consensus via Threshold Cryptography | drand dcrypter: a modular network for threshold signing
• Impossible Cloud — Experience Impossible Cloud Storage: Secure, scalable, performant. Decentralized architecture, S3 API compatibility, 100% durability. Start free trial now.

Portfolio highlights

• Glue — Glue is smarter work chat.
• Lighter — Lighter develops software focused on financial applications. It designs tools to support financial tasks and processes. The company creates solutions for various financial needs. Its products aim to streamline financial activities. Lighter specializes in software development for finance.
• Zcash Open Development Lab — Zodl is a mobile wallet for sending and managing private Zcash transactions, with encrypted payments and full user control of funds.

Portfolio highlights

• Levr Bet — LEVR provides users with a decentralized sports betting platform that combines leveraged DeFi with traditional sports betting.
• TRM Labs — Next Generation Blockchain Intelligence | Monitor, Investigate, and Mitigate Crypto Fraud and Financial Crime
• Rio Network — Rio Network is an operator of a public proof-of-stake blockchain platform intended for the issuance, investment, and life-cycle management of digital securities and crypto assets.

Portfolio highlights

• Ethernity — The Ethernity Chain ecosystem has been rebranded to Epic Chain following a community DAO vote.
• Ethernal Labs — Ethernal Labs is a multidisciplinary studio that is leveraging the interactivity and utility of web 3 technology. Ethernal Labs is the premier creative and technology studio for NFT Creation, Metaverse Integration, Fan Tokens, P2E Gaming, and Virtual experiences.
• E Money Network — E Money Network is a modular Real-World Asset (RWA) blockchain technology designed with compliance at its core.

Portfolio highlights

• MoonPay — MoonPay offers a fast and simple way to buy and sell cryptocurrencies. Buy crypto with credit card, bank transfers or Apple Pay today.
• Conta Simples — Conta Simples is the all-in-one finance plataform. The union of checking account, expense management software and corporate cards in one place. We bring peace to finance teams and entrepreneurs. Control, visibility, autonomy and decentralization of payments for SMBs in Latam.
• Diadia Health, Inc — An AI medical reasoning platform that helps clinicians analyze the root causes of symptoms and create personalized protocols that drive better outcomes.

Portfolio highlights

• Karat Financial — Karat is the best card for creators, helping you save money, earn rewards, and grow your channel faster - because content IS a business.
• Otis — Otis is a fractional ownership platform that makes it possible for almost anyone to buy and sell shares of collectibles, sneaker grails, rare comics, art, and more. Low minimums. Get started today.
• Reservoir — Infrastructure and APIs to bring efficient token markets to every chain, wallet, and app

Portfolio highlights

• Aark — Trade crypto perpetuals with up to 1000x leverage, zero gas fees, and an industry-low 0.01% trading fee. Earn payback on losses with VIP rewards. RWA & altcoin perps on Arbitrum. Backed by OKX Ventures.
• Itheum — As we enter the web3 and metaverse era; Itheum unlocks data silos and generates new value for your data.
• Fanable — Fanable is a Web3 marketplace specialized in Pokémon, comic books, and collectibles, allowing users to purchase, sell, and engage with their favorite products in both physical and digital forms.

Portfolio highlights

• Gro — Gro protocol is a stablecoin yield aggregator that tranches risk and yield. The first two products built on it are the PWRD stablecoin with deposit protection and yield, and Vault with leveraged stablecoin yields.
• TRM Labs — Next Generation Blockchain Intelligence | Monitor, Investigate, and Mitigate Crypto Fraud and Financial Crime
• Bullish Global — Bullish Global is a new blockchain-based cryptocurrency exchange designed to combine the performance, user privacy, and compliance offered by central order book technology with the vertically integrated user benefits of decentralized finance (DeFi) market architecture.

Portfolio highlights

• Tradoor — Tradoor protects traders, LPs, and the protocol against unforeseen market fluctuations by using clever math and safety measures to enable traders to trade with confidence.
• Runes DEX — Swap Runes for BTC seamlessly, enjoy low fees, fast transactions, and earn yield as a liquidity provider.
• Nested — The best decentralized portfolio management & copy trading experiences

Portfolio highlights

• Arwen — Arwen gives protection while trade on cryptocurrency exchanges. They are a team of seasoned experts in cryptography, network and cloud security. Arwen aims to be the most secure standard of trading as a technology built for centralized cryptocurrency exchanges. Their protocol and system has been developed by a team with over a decade of expertisein cryptographic standards and network security. They are building better crypto trading infrastructure and have the best team in the business.
• Cenoa — Cenoa - The smartest way to get paid globally!
• Chainlink — Chainlink is the most widely used oracle network for powering hybrid smart contracts, enabling any blockchain to securely access off-chain data & computations.

Portfolio highlights

• Bikky — Bikky is the #1 CDP for Restaurants and the Switzerland of guest data. We break down data silos across operating and marketing systems and surface the business insights restaurant marketers and c-suite leaders need to truly see customers. With Bikky, act faster and smarter to grow the business.
• Pienza — Pienza Ventures - We help Indian Startups win in the US Market
• Loon — Loon is a financial technology startup dedicated to developing a regulated, transparent, and trusted Canadian-dollar stablecoin.

Portfolio highlights

• ARX — ARX smart contracts and HaLo chips enable creators build decentralized, immutable and composable physical crypto assets.
• Impossible Cloud — Experience Impossible Cloud Storage: Secure, scalable, performant. Decentralized architecture, S3 API compatibility, 100% durability. Start free trial now.
• Open Game Protocol — Open Game System is a project that helps web games work better on phones, allowing the games to use tools that phones already have.

Portfolio highlights

• Cowboy Snake — Cowboy Snake is the TvT play-to-earn game inspired by snake on the blockchain. Cowboy Snake is a product of OrenCT Ltd.
• Formless — Formless enables gamers, NFT enthusiasts and digital collectors to find their favourite game while helping games find their targeted fans.
• Clear Protocol — Clear Protocol, Inc. is a healthcare IT company. Our product, Clear Protocol, is Software-as-a-service for hospitals, clinics, and medical offices.

Portfolio highlights

• ETHGas — ETHGas aims to redefine how users engage with Ethereum by providing low-latency, 3ms settlement times, and real-time trading, as well as a comprehensive product suite for exact order execution.
• GenLayer — GenLayer is a platform that focuses on intelligent contracts.
• dWallet Labs — dWallet Labs Ltd., based in Tel Aviv, Israel, a cybersecurity company specializing in blockchain technology, is building SingleWallet, the first interface to interact with dWallets on the Odsy Network. The mission of dWallet Labs is to build protocols and solutions on top of the Odsy Network.

Portfolio highlights

• Rivero — Rivero delivers AI-powered automation for banks, streamlining payment dispute management, chargebacks, and card network compliance through Amiko and Kajo.
• Harbor — Harbor is a purpose-built trading platform for wallets to access liquidity in a performant execution environment.
• Senken — Secure and trusted carbon credit portfolios built for your industry. Offset CO2 footprint with our credits.

Portfolio highlights

• Sticky: AI Game Maker + Gaming Platform — Sticky is a mobile social and gaming superapp with an AI Game Maker at its center. Using AI, Sticky lets creators make professional-quality games on their phones or in their browsers in a few minutes without touching a line of code. Creators can publish on the Sticky platform and earn money. They can also integrate social features, collectibles,in-game-purchases, leaderboards, and more to their games, as well as submit their games to game jams. Sticky members can play thousands of games and make friends, chatting in clubs, streaming, competing in tournaments, and more.

Portfolio highlights

• ether.fi — EtherFi is a non-custodial decentralized ETH staking method that distributes staking to node operators in exchange for rewards.
• Azuro — Powerful tooling, oracle & liquidity solutions for any EVM predictions & gaming ecosystem
• QED Protocol — A trustless, scalable, decentralized compute protocol for a fairer internet focused on user privacy and platform transparency.

Portfolio highlights

• Ad-Shield — Start measuring revenue lost to ad blockers and learn how to get additional revenue through Ad-Shield Recovery today
• Injective — Explore Injective: the high-performance blockchain powering decentralized finance, governance, and next-gen Web3 apps with unmatched speed and scale.
• Decentralised Gaming Ventures — D.G.Pals is a virtual pet, NFT Game Project that focuses on Squad-battler (PvP and Competitive), Siege Defence, Clan System, and various types of genre revolving around the IP as part of the ecosystem in the D.G.Verse.

Portfolio highlights

• Pluno — AwesomeQA is an AI customer support solution for Web3, designed to deliver best-in-class user support while reducing the need for manual labor.
• Squid — Buy, swap, and bridge crypto across 100+ chains and 20k tokens. Fast, cheap, reliable. Used by 1M+ users and 1K+ integrators.
• Limited — Secure your treasury and scale your business globally with a truly self-custodial account that only you control. No banks. No middlemen.

Portfolio highlights

• Nibiru Chain — Nibiru is a smart contract ecosystem with a high-performance, EVM-equivalent execution layer. Nibiru is engineered to meet the growing demand for versatile, scalable, and easy-to-use Web3 applications.
• bitSmiley — BitSmiley offers comprehensive Bitcoin DeFi solutions to bridge the stablecoin and lending infrastructure gaps within the Bitcoin ecosystem. Its main product is an over-collateralized stablecoin based on Bitcoin. Users can utilize Bitcoin as collateral for BitSmileyDAO and Mint BitUSD.
• Doubler Pro — Join Doubler, become a Winner.

Portfolio highlights

• MemeFi — MemeFi is a blending of social technology with Web3 features on-chain Social Tech app might be focusing on integrating blockchain technology with social interactions, which could offer benefits like decentralization and enhanced privacy.
• Cookie3 — Cookie3 utilizes off- and on-chain analytics and an AI data layer to determine quality users who bring value on-chain and reward them for their contribution. It's a three-platform hub for businesses, creators, and users with a unique value offering for all.
• RunesFi — RunesFi is a one-stop DeFi platform that provides an easy-to-use, secure, and efficient trading experience.

Portfolio highlights

• Hedget — Hedget is a Defi-focused derivatives platform which operates a decentralized options trading.
• Chromia — Chromia is a relational blockchain platform, making it easy for people to build decentralized apps in the real world, for a better world.
• KILT Protocol — KILT Protocol is an open-source blockchain protocol for creating Web 3.0 credentials that are verifiable, revocable, and anonymous.KILT provides Internet Data Sovereignty and puts users in control of their data, allowing them to choose which data to share, when, with whom, and why. It's a blockchain protocol that creates a distributed onlinetrust market to help people manage their online trust connections.It was founded in 2018 and is based in Berlin, Berlin.

Portfolio highlights

• STON.fi — STON.fi is a decentralized automated market maker (AMM) built on the TON blockchain. Explore the full range of STON.fi. Swap cryptocurrencies, stake tokens, provide liquidity on the TON blockchain.
• OneBalance — OneBalance is a new framework for credible accounts - combining chain abstraction, gas abstraction and permission management to solve the fragmented Web3 user experience.
• RedStone — RedStone delivers frequently updated, reliable and diverse data for your dApp and smart contracts.

Portfolio highlights

• 0G Labs — The First Decentralized AI Operating System
• Yellow — Yellow is a financial services provider of software, analytics, and investments in blockchain startups.
• Mind Network — The 1st Fully Homomorphic Encryption (FHE) Restaking Layer for AI and POS Networks. Mind Network is backed by Binance Labs, Hashkey, Big Brain, Chainlink, etc.

Portfolio highlights

• NodeOps — Experience seamless node deployment and management through a permissionless, incentivized, and secure node infrastructure orchestration layer
• RiskLayer — RiskLayer is an economic security middleware for DeFi and providing services and validating Creating positive feedback loops.
• E Money Network — E Money Network is a modular Real-World Asset (RWA) blockchain technology designed with compliance at its core.

Portfolio highlights

• Soulbound — Saga is a decentralized gaming community that aims to improve and grow the metaverse by creating a chain-agnostic market infrastructure.
• Term Labs — Fixed rate lending for everyone
• Pell Network — Pell Network is a precisely constructed multi-layered restaking network with a great user experience, clear role segregation, and a closed-loop business logic chain.

Portfolio highlights

• Revolut — Join 40+ million customers globally using Revolut to send money to 160+ countries, hold up-to 36 currencies in app, spend in 150+ currencies, and manage their money.
• Platfora — Platfora’s mission is to empower customers to transform their businesses into fact-based enterprises. Platfora's Big Data Analytics Platform masks the complexity of Hadoop, making it easy for customers to understand all the facts in their business across events, actions, behaviors and time.
• Lead — Lead Bank is a community-minded, independent commercial bank with a national client base recognized for its imaginative approach to community banking.

Portfolio highlights

• Drosera — Drosera is a decentralized incident response system that uses hidden security intentions to contain and mitigate attacks.
• bbox — bbox offers professional trading on the Decentralized Perpetual Exchange and hybrid markets.
• Delegate — Delegate focuses on increasing the security of on-chain identities and digital asset management such as NFTs and ERC20 tokens.

Portfolio highlights

• Ion Protocol — Ion is an Open Source Protocol built to support Ethereum stakers and restakers, to unlock a world of new applications for their assets.
• Baselayer — Baselayer automates business risk assessment and eliminates B2B fraud in the financial sector. It offers services such as business verification (KYB), fraud detection, business onboarding optimization, risk profiling, portfolio monitoring & alerting, and workflow automation. Baselayer empowers 100s of financial institutions, governmentagencies, lenders, and fintech to unlock instant trust with any business in America.
• Blueprint Finance — Blueprint Finance develops protocols and infrastructure to advance on-chain financing.

Portfolio highlights

• Vivid Labs — Vivid Labs simplifies the complexities of the NFT revolution with a comprehensive, easy to use software platform that brings NFTs to everyone.

Portfolio highlights

• Rice AI — Rice AI is a decentralized AI smart-contract protocol designed to provide autonomous training and incentive mechanisms for robots.
• Depinsim — DepinSim is a blockchain-based eSIM platform that lets users access global mobile data and earn rewards.
• Block Street — Blockstreet is a multichain platform driving USD1 stablecoin adoption, smart contract deployment, and cross-chain DeFi growth tools.

Portfolio highlights

• Heurist — Heurist is a Layer 2 network for AI model hosting and inference based on ZK Stack. It offers serverless access to open-source AI models stored on a decentralized network of computer resources.
• assisterr — Assisterr is building an AI tokenization stack to ensure fair compensation for data owners and contributors. The platform manages the entire lifecycle of SLM training, enabling features like data provenance tracking, fine-tuning, and the launch of SLM-powered Agents. Web3 component allows data owners to contribute their data and expertise todomain-specific SLMs and capture the value from such contributions.
• bitSmiley — BitSmiley offers comprehensive Bitcoin DeFi solutions to bridge the stablecoin and lending infrastructure gaps within the Bitcoin ecosystem. Its main product is an over-collateralized stablecoin based on Bitcoin. Users can utilize Bitcoin as collateral for BitSmileyDAO and Mint BitUSD.

Portfolio highlights

• IMUA — IMUA is a Layer 1 blockchain that provides shared security by combining decentralized security from well-known blockchains.
• Exocore — Exocore is the layer one blockchain for aggregated security.
• Voyage — Voyage AI is an AI infrastructure project building the first GEOFi network to make AI-generated content citable.

Portfolio highlights

• Mon Studios — An indie game development studio
• Convergence — Convergence is a decentralized governance aggregator that seeks to maximize the functionalities and capital efficiency of several protocols by offering staking opportunities for various governance tokens, vault tokens, and other yield-bearing assets.

Portfolio highlights

• Aethir — Power Ultra-Low Latency Gaming & AI Experiences.
• Elixir — Powering deUSD, a yield bearing and fully collateralized decentralized dollar on the Elixir Network, bringing institutional-grade liquidity to RWAs.
• Zcash Open Development Lab — Zodl is a mobile wallet for sending and managing private Zcash transactions, with encrypted payments and full user control of funds.

Portfolio highlights

• Kuru — Kuru is an on-chain order book exchange.
• fomo — Fomo is a cutting-edge fintech startup revolutionizing the financial landscape through innovative technology and strategic partnerships.
• Commonware — Commonware is a startup that supplies developers with a "anti-framework" — effectively all of the building pieces for developing a blockchain — in order to go beyond the era of standardized, general-purpose software kits.

Portfolio highlights

• D3 — D3 - DNS Domains for Web3
• Optimum — Optimum constitutes a decentralized, high-performance memory infrastructure tailored for use across various blockchains.
• Prime Intellect — Prime Intellect democratizes AI development at scale. Our platform makes it easy to find global compute resources and train state-of-the-art models through distributed training across clusters. Collectively own the resulting open AI innovations, from language models to scientific breakthroughs.

Portfolio highlights

• OneBalance — OneBalance is a new framework for credible accounts - combining chain abstraction, gas abstraction and permission management to solve the fragmented Web3 user experience.

Portfolio highlights

• Novastro — Novastro is a Layer 2 chain for RWAs powered by AI that integrates MoveVM and EigenLayer AVS, delivering Ethereum-level security and Move’s scalability to unlock tokenised yield opportunities across RWAs & DeFi protocols.
• SecondLive — SecondLive is a diversified metaverse focused on building social networks and supporting creator economic activities.
• Hybrid — Hybrid is a fintech company that offers a decentralized central AI tool with Web3's ecosystem of AI experts, agents, and data.

Portfolio highlights

• MemeFi — MemeFi is a blending of social technology with Web3 features on-chain Social Tech app might be focusing on integrating blockchain technology with social interactions, which could offer benefits like decentralization and enhanced privacy.
• Yellow — Yellow is a financial services provider of software, analytics, and investments in blockchain startups.
• aPriori — aPriori is a monad-native MEV infrastructure and liquid staking mechanism developed for parallel executions.

Portfolio highlights

• Blum — Blum is a decentralized exchange platform
• DoubleZero — DoubleZero is developing a global fiber network intended for high-performance distributed systems and blockchains. It seeks to enhance blockchain performance by establishing a dedicated physical infrastructure layer for communication.
• Avara Ventures — Avara creates smart contract-enabled products and public goods (open source protocols) that incorporate decentralized blockchain technologies and token-based economies.

Portfolio highlights

• Setscale — Setscale simplifies trade & empower companies to scale with Purchase Order Financing. Setscale only get paid once you do! We fund Supply. You meet demand.
• Figure — Figure is the first-of-its-kind AI robotics company bringing a general purpose humanoid to life.
• Clara — Clara is an end-to-end corporate spend management solution for growing businesses in Latin America. Clara's credit cards and spend management solution are already being used by thousands of top companies in Mexico, Brazil, and Colombia.The company is backed by leading regional and global investors, such as Coatue, DST Global, monashees,Kaszek, Canary, Picus Capital, Avid Ventures, A*, Box Group, SOMA Capital, SV Angel, and dozens of angel investors including some of the most successful founders in LatAm and the world. Clara reached a unicorn valuation in record time and has been recognized as a Great Place to Work and a LinkedIn Top Startup.Clara is creating the future of how company finances are run and helping our customers be more successful. Clara aspires to empower companies to operate with agility and financial clarity, ultimately increasing the economic competitiveness of Latin America.

Portfolio highlights

• Mon Studios — An indie game development studio

Portfolio highlights

• Keplr — Introducing the first, and leading, IBC-enabled wallet for Cosmos and beyond
• Reppo Labs — Blockchain Network that connect Data Owners with AI Developers and AI agents through Programmable IP Co-ownership
• Prodia — Prodia is a multimedia design software and developer of artificial intelligence that creates APIs and images.

Portfolio highlights

• Othentic — Othentic provides builders with the most intuitive way to spin up a modular blockchain on top of EigenLayer
• BabylonChain — Babylon is a VC-backed blockchain project founded by Claude. E. Shannon Award recipient, Professor David Tse from Stanford University. The project’s mission is to bring Bitcoin’s unparalleled security to all PoS blockchains in the world. To this end, we are building, as the bridge between Bitcoin and the PoS world, a new public Cosmos-based PoSblockchain called Babylon with a native token.
• Cube Group — Cube is the world's fastest crypto exchange. Built by and for traders, Cube is the most liquid, secure and advanced cryptocurrency exchange.

Portfolio highlights

• Mon Studios — An indie game development studio
• Ambient — Swap cryptocurrencies like a pro with Ambient. Decentralized trading is now better than ever.
• Rysk Finance — Rysk Finance is developing a dynamic hedging vault to assist in the creation of alternative, decentralized financial assets that can be used to protect against financial market risks. The service allows customers to buy and sell options on crypto assets, giving them the opportunity to protect themselves against downturns in the market if they sodesire.

Portfolio highlights

• LOScoin — LOScoin is a web3 gaming and social application based on telegram bot. LOScoin is committed to profoundly combining Web3's novel interactive experience with the passion of LOScoin's MEME community, creating a highly engaging, entertaining, and economically active DAO community, and providing users with a completely new gaming and socialexperience.
• Sapien — Sapien offers Data Labelling Services with RLHF to fine-tune your LLMs potential. Improve model performance with better data to improve outcomes. Consult us now!
• Pixion Games — Pixion Games is a studio focused on building competitive esports games for mobile device.

Portfolio highlights

• BlockGames — BlockGames is a cross-game, cross-chain, decentralized player network accelerating user growth for games, with personalised rewards for players.
• Holograph — Holograph enables NFTs to survive and bridge between blockchains while maintaining total data integrity. The company was founded in 2020 and is based in Los Angeles, US.
• Uncharted — Uncharted is a cryptocurrency-based gaming platform helps game developers and companies.