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Top 50 Medical Device Startup Investors in Middle East in September 2025

Last updated: Sep 2025 A list of 50 angel investors and VC (Venture Capital) funds that invest in Medical device startups based in Middle east. We rank investors based on the number of investments they made in Medical device companies from Middle east. We update this investor list every month.

Top 50 Medical Device Startup Investors in Middle East in September 2025

Investor	Medical Device Middle East investments
Diffusion Capital Partners	9
Israel Innovation Authority	8
Pontifax	8
Trendlines Group	7
Accelmed	5
OurCrowd	5
J-Ventures	4
Elron Ventures	4
Btomorrow Ventures	4
Agriline	4
OrbiMed	3
OTV	3
Eczacıbasi Momentum	3
TT Ventures	3
Rimonci Capital	3
Magma Venture Partners	3
Longevity Venture Partners	3
Docor International Management	3
Triventures	3
Kli Capital	2
TechWald Holding S.p.A.	2
Sanara Ventures	2
Zohar Gilon	2
Emerge Ventures	2
Ak Portfoy	2
GlenRock Israel	2
Mithril Capital Management	2
ZORA Ventures	2
Yehuda Zisapel	2
HealthpointCapital	2
Italian Angels for Growth	2
Merz Therapeutics	2
aMoon Fund	2
Dov Moran	2
Clal Biotechnology Industries	2
Joyance Partners	2
Chartered Opus	2
Laborie Medical Technologies	2
XT Hi-Tech	2
Tarvenn Ventures	2
Arkin Holdings	2
ALIVE Israel HealthTech Fund	2
Sofinnova Partners	2
Maccabi Fund	2
Johnson & Johnson Robotics and Digital Solutions	2
MTIP AG	2
Shimon Eckhouse	2
Rapha Capital Management	2
Terra Venture Partners	2
Medtronic	2

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Investor list

Diffusion Capital Partners (DCP) is Turkey's leading Venture Capital fund manager with a focus on deep-tech opportunities.

Investment focus

Software, Information Technology, SaaS
Seed, Series A, Funding Round
Turkey, United States, United Kingdom

Portfolio highlights

Khenda — Khenda is an AI-based video analytics platform that helps manufacturing plants to increase their safety, efficiency, and quality at production lines by analyzing manual activities.
Mixer Games — Pioneers who shape the entertainment of the future
Gowit Technology — Unlock your retail media potential with GoWit's omnichannel Retail Media Advertising platform. Expand your audience reach, optimize bidding, and leverage first-party data for maximum conversions and privacy protection.

The Israel Innovation Agency, the Innovation Authority, was established in 1965 as the Office of the Chief Scientist of the Ministry of Industry and Trade and was designed as a body that supports R & D conducted in the framework of government research institutes. Industrial development in order to increase industrial exports of high-techproducts. The Chief Scientist focused on reducing the risk by participating in financing the project, which the private companies chose and led.

Investment focus

Health Care, Medical Device, Biotechnology
Grant, Seed, Pre-Seed
Israel, United States, Mali

Portfolio highlights

Algocell — Optimize precision fermentation and cell culture bioprocesses using Digital Twin, AI and Hybrid Models. Create your first model now!
Firewave — Firewave is a climate-tech startup developing AI-powered acoustic sensors for early wildfire detection. Our solution detects small fires within minutes—well before they escalate—helping communities, utilities, and critical infrastructure reduce damage, response time, and costs. Using edge AI and long-range connectivity, Firewave enables coverageacross vast forested and hilly terrains. We focus on deploying our IoT system near settlements and critical infrastructure, where early response is crucial and traditional solutions often fall short.
Lowental Hybrid — Lowental Hybrid technology combines fuel-based propulsion with electric power, enabling longer operating hours while preserving the low noise levels characteristic of electric systems.

Pontifax is a healthcare-dedicated venture capital firm.The fund focuses on innovative bio-pharma opportunities.

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Series C
United States, Israel, France

Portfolio highlights

ADCendo — ADCendo ApS is a biotech company dedicated to developing new types of anti-cancer drugs. We focus on antibody-drug conjugates (ADCs) directed at novel targets, that have been found to be overexpressed by several cancer forms, that are all characterized by a significant unmet need for novel treatment.
Lutris Pharma — Improving anti-cancer therapy by reducing dose limiting side effects
Indapta Therapeutics — Indapta Therapeutics is a privately held biotechnology company developing an NK (natural killer) cell therapy platform for the treatment of blood and solid tumor cancers.

Trendlines Group invents, discovers, invests in, and incubates innovation-based medical and agrifood technologies. Trendlines invests principally through medical and agrifood incubators in Israel and in Singapore, its in-house innovation center, Trendlines Labs, and its Funds - the Trendlines Agrifood Fund and the Bayer Trendlines Ag InnovationFund.The company was founded in 1993 and is headquartered in Misgav, Israel.

Investment focus

Biotechnology, Health Care, Medical Device
Seed, Funding Round, Series A
Israel, Singapore, United Kingdom

Portfolio highlights

AgriG8 — AgriG8 is an enterprise designed to align, collaborate, de-risk and grow value chains and ecosystems within the agricultural industry.
Celleste Bio — Celleste is a business that specializes in employing cell culture techniques to produce high-value cocoa ingredients, removing the need for cocoa trees to be grown.
Arcuro Medical — Arcuro develops a new repair system for meniscus tears of the knee. Arcuro’s proprietary SuperBall repair system consists of a knotless, all-suture anchor and innovative delivery system. The company was founded in 2013.

Accelmed is a venture capital firm that funds private and public medical device companies with significant market potential and proven clinical data.Concentrating on medical device companies that have already reached the revenue stage enables the firm to assist companies in benefiting from its managerial capabilities and financial resources.Together with the management teams of their portfolio companies, the Accelmed can steer the way from the clinical-stage to a profitable business with a clear commercial plan, thereby accelerating the path to a successful exit.In 2009, Mori Arkin and Uri Geiger, the co-founders of Accelmed, established the firm in Herzliya, Tel Aviv.

Investment focus

Health Care, Medical Device, Medical
Funding Round, Series A, Series D
Israel, United States

Portfolio highlights

Revamp Medical — Revamp medical was founded in 2016 with the goal of resolving one of the most urgent unmet needs in Acute Heart Failure patients. Targeting a market of >1M annual admissions in the US with a direct cost of $65B, Revamp is set to deliver an easily adoptable solution using its patented temporary catheter, Doraya™.Revamp has a seasoned team ofprofessionals with a proven track record in leading multiple med-tech startups.
UltraClear —
Minerva Surgical — Minerva Surgical develops minimally invasive devices to treat the root causes of Abnormal Uterine Bleeding.

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Investment focus

Software, Artificial Intelligence, Machine Learning
Series B, Series A, Seed
Israel, United States, New Zealand

Portfolio highlights

Lidwave — Lidwave’s deep-tech solution revolutionizes 3D sensing and the verticals relying on it by examining the biggest challenge in LiDAR technology from a new perspective, free of bandwidth limitations.
Kando — Kando is an end-to-end solution that creates continuous awareness of events in the collection system. Kando enables utilities to remotely and continuously improve their operations by providing the following features:• Realtime wastewater quality data across the collection system • Pinpoint sources of pollution • Early warnings of damaging WWTPinfluent quality • Machine learning that evolves with your network • Autonomous sampling units • User fee calculator • Customized pollution alerts • A user-friendly, online interface • Detection of COVID-19 infection rates (New)The combination of these actionable insights results in:• Reduced CAPEX/OPEX • Greater WW reuse capabilities • Improved public health • Cleaner environmentsKando has been deployed in Los Angeles, Milan, Brisbane, and many other cities. To gain a greater understanding of how our system can help your organization, visit our homepage at www.kando.eco.
Blue Tree Technologies Ltd. — Blue Tree’s mission is to develop a sugar reduction platform for industrial applications in the drinks industry.

J- Ventures is a Silicon Valley based group of VC funds with over $60m under management. Backed by 400+ leading Investors ( 140+ Serial founders, 100+ VCs, 170+ Fortune 500 Executives) as LPs. Our active-LP venture fund brings the power of this connected & intellectual capital to add real value to the companies we invest in and create aremarkable difference by helping our founders grow and scale to markets quicker. Based in Silicon Valley with investors from 15 communities - Tel Aviv, NYC, LA, London, Miami, Boston, and more. Since 2016 the group made over 50 investments, 4 unicorns and over 10 exits.

Investment focus

Software, Health Care, Machine Learning
Series A, Seed, Pre-Seed
United States, Israel

Portfolio highlights

Epic Cleantec — Epic Cleantec provides sustainable onsite wastewater reuse solutions for the built environment
Onebeat — Onebeat helps retailers, wholesalers, and brands achieve results through operational optimization. It offers solutions for the needs of the technology of retail. It develops platforms that aim to help businesses optimize how they handle their retail. It's headquarters is in Petach Tikva in Israel and it has branches globally.
Oso Semiconductor — A New Approach to RF Beamforming

Elron Ventures is an early-stage investor committed to turning promising ideas into global industry leaders, with a proven track record of investments and successful M&As worldwide. Elron invests in cyber security and B2B software. Since its establishment in 1962, Elron stands on the forefront of Israeli innovation both as a founder and earlyinvestor in companies across various industries such as Elbit, Medingo, Given Imaging, Cloudyn, Cyber Secdo, and Alcide.

Investment focus

Information Technology, Health Care, Software
Seed, Series A, Funding Round
Israel, United States, China

Portfolio highlights

Creednz — Creednz is a company that provides financial data management system that involves internal financial data sets.
Entitle — Control access to your organizational cloud resources without creating bottlenecks or friction while creating a seamless experience for employees.
Tamnoon — Tamnoon develops a state-of-the-art cloud security platform to empower security teams and manage cloud risks effectively. By harnessing the power of AI combined with human expertise, the company empowers security teams and equips organizations of all sizes with exceptional cloud protection capabilities.

Btomorrow Ventures (BTV) is the corporate venturing unit of BAT. BAT is building A Better Tomorrow by reducing the health impact of its business by transforming into a truly consumer-centric multi-category CPG company. We are dedicated to partnering with ambitious and passionate entrepreneurs to realise their vision by providing a platform toenhance innovation and accelerate growth.

Investment focus

Health Care, Wellness, Food and Beverage
Series A, Seed, Series B
United States, United Kingdom, India

Portfolio highlights

Tru — Obsessively formulated by fusing flavor with function, each of our tasty innovations perform when you need it most. From the time you wake up until the second your head hits the pillow, we elevate every moment one sip at a time.
Awake Chocolate — AWAKE Chocolate combines delicious milk chocolate.
PHILTER Labs — Philter Labs presents an innovative smoke filter for E-Cig, Vape Pen, & CBD Pen. Filters smoke from entering shared space while you still enjoy the experience.

Agriline is the investment vehicle owned by a trust of which Trendlines' controlling shareholder Vincent Tchenguiz.

Investment focus

Health Care, Medical Device, Medical
Seed, Funding Round, Series A
Israel

Portfolio highlights

Phytolon — Phytolon revolutionizes the way food colors are produce, by Leveraging a novel and sustainable technology for production of healthy food colors in high quality at low costs. Phytolon's mission is to exploit scientific advancement promote human health and environmental sustainability
Vessi Medical — Vessi Medical is developing an innovative, IP protected cryo spray for hollow & humid organs, a new approach in the treatment of Non Muscle Invasive Bladder Cancer (NMIBC).
SetBone Medical — SetBone Medical develops a new bone cement for the treatment of VCF and primarily caused by osteoporosis.

Leading Global Healthcare Platform with Deep Proprietary Resources and Global Industry Coverage.

Investment focus

Biotechnology, Health Care, Medical
Series B, Series A, Series C
United States, China, Israel

Portfolio highlights

CHARM Therapeutics — CHARM Therapeutics uses deep learning on 3D molecular configurations to develop molecule therapeutics to target pathogenic proteins.
Treeline Biosciences — Treeline Biosciences is a biotech company building transformative precision medicines for patients with cancer and other serious conditions. The company was founded in 2021 and is headquartered in Stamford, CT.
Congruence Therapeutics — ABOUT US We are a drug discovery company that is uniquely harnessing the power of protein dynamics, biophysics, machine learning and computational chemistry. Our Science Traditional drug design is limited At Congruence,

OTV focuses on round A+ startups that aim to make a significant impact on people's lives. Our focus is on entrepreneurs with innovative ideas who are advancing the global state of well-being. Come join the digital health revolution, and be a part of transforming the healthcare industry.

Investment focus

Health Care, Medical, Artificial Intelligence
Series A, Series B, Seed
United States, Israel, Ghana

Portfolio highlights

Scopio — Buy & sell images on the largest Solana Photography NFT Marketplace. Find high-quality stock images & hire artists from around the world.
Scopio Labs — Scopio Labs is a provider of Full Field Morphology dedicated to unlocking the potential of imaging and AI in hematology. Uncovering actionable insights from vast amounts of data readily available in the average blood sample and bone marrow aspirate, Scopio's solutions will aim to showcase thousands of cells at scale in high resolution, toenable new hematology diagnostic methods.
Stake — Renters earn Cash back for rent. Building operators outperform the market. That's the Stake win-win. Find out how we're building the financial tools for the next generation of rentals.

Eczacıbaşı Momentum invested in three venture companies and a venture capital fund; Their goal is to invest US$30 million over the next five years as they continue to partner with funds and startups that shape the new normal of modern life, focusing on well-being, consumption, and home-living.

Investment focus

Medical Device, Information Technology, Neuroscience
Seed, Series A, Funding Round
Turkey, United States

Portfolio highlights

Newlab — Systems for scale
Ecomercek — Ninico is a modern and flexible Minimal eCommerce Laravel script. This script is suited for electronic, organic and grocery store, furniture store, clothing store, hitech store and accessories store...
RS Research — RS Research is a next generation therapeutics company developing novel nanomedicines. We have developed a pioneering class of nanocarriers with which we currently have proprietary programs in various stages of preclinical development for treatment of cancer.Our nanocarrier platform is highly tunable with a plug & play approach, allowingspeedy development of targeted nanomedicines with superior performance.Along with moving our very own candidates toward clinic, we provide preclinical services to industrial and academic partners. We have specific expertise in biosimilar characterization as well as in vivo experiment design.

TT Ventures is the corporate venture capital arm of Turk Telekom.

Investment focus

Software, Information Technology, Artificial Intelligence
Seed, Funding Round, Pre-Seed
Turkey, United States, United Kingdom

Portfolio highlights

VenueX — VenueX enables retailers to showcase their products, POI and indoor maps to shoppers searching online!
OctoXLabs — OctoXLabs is dedicated to tackling the most pressing challenges in the fields of Information Technology and Cybersecurity, delivering innovative solutions that enhance system resilience, data protection, and operational efficiency for organizations navigating an increasingly complex digital landscape.
Milvus Robotics — Transform material handling with autonomous mobile robots solutions and fleet software. Smarter, safer, and scalable automation.

A dedicated to China-Israel cross border investment.

Investment focus

Health Care, Medical Device, Eyewear
Series A, Seed, Series B
Israel, France, United States

Portfolio highlights

EyeYon — EyeYon Medical is an Israeli start-up company that develops innovative medical devices for the treatment of corneal edema.EyeYon Medical was founded by Dr. Daphna Ofer, a senior ophthalmologist, Dr. Arie Marcovich, a senior cornea surgeon, and Nahum Ferera, an experienced business executive. The company operates within the Van Leer TechnologyIncubator.
TECLens — TECLens is creating a crosslinking technology that may accurately fix vision issues in healthy eyes as well as treat keratoconus. It provides patients with presbyopia with the ability to regain their ability to read at a distance, controls children's progressive myopia, corrects adult vision problems like hyperopia and low-order myopia, andmore.
Laclarée — Laclarée develops a pair of adaptive eyeglasses for presbyopia. Its patented technology allows the eyeglasses to adapt in real-time to the scene viewed by the wearer. This major innovation will help milllions of people 45+ years, who are not satisfied with current solutions (progressive lenses, multiple pairs, etc...).

Magma is Israel's leading venture capital firm specializing in early-stage investments in communication, semiconductors, internet and media. They seek bright ideas, infuse them with experience and foresight, and facilitate their rise as industry leaders that redefine the global communications sector. They use their experience and sectorspecialization in cooperating with entrepreneurs, industry experts, and other investors to define the future of the communication, semiconductors, internet and media arenas. Their goal is to foster and enable the flow of innovation from an idea's early stages and through a company's emergence as a leader within its dynamic market. They understand the local market and help to influence the global one.

Investment focus

Software, Artificial Intelligence, Mobile
Series A, Series B, Seed
Israel, United States, Mexico

Portfolio highlights

Ubeya — Ubeya is an employee management platform that helps manage shift and hourly employees. Offering an and-to-end solution for Staffing Agencies, Catering and Hospitality industries, Delivery Fleets, and more. Helping Managers, Payroll, HR and Legal departments to digitize operations with an employee app and a client portal. Our modular system allows each business to choose the functions that best serve their business: Schedule, Clock-in, Track, Communicate and Pay your employees with Ubeya.
Intezer — The enterprise leading AI SOC agents for security teams, trusted to automate, investigate, and respond with unmatched speed and accuracy.
ScyllaDB — ScyllaDB is the distributed database for data-intensive apps that require high performance and low latency.

Longevity Venture Partners is an early-stage venture capital firm committed to assisting entrepreneurs in the Silvertech, Healthcare, and Wellness sectors.

Investment focus

Health Care, Medical Device, mHealth
Seed, Pre-Seed, Series A
Israel, United States

Portfolio highlights

Faireez — Optimizing tenants' lifestyle and convenience through enabling them with a hotel-like home cleaning service
Lembas — Lembas is a foodtech startup that has developed "GLP-1 Edge," a patent-pending peptide ingredient designed to naturally boost the GLP-1 hormone, which helps regulate appetite and metabolism for weight management. Using AI-driven discovery and licensed technology from Tel Aviv University, Lembas offers this peptide powder as abusiness-to-business ingredient for food and supplement brands, providing a science-backed, non-pharmaceutical alternative to weight loss drugs with no reported side effects
Exero Medical — Exero Medical is a medical device manufacturing company. It develops a biodegradable wireless sensor for early detection of anastomotic leaks following GI Surgery. Its system is designed to prevent complications by warning physicians of a potential leak, enabling early intervention.The company was founded in 2018 and is headquartered in OrYehuda, Israel.

Docor International B.V. is a fully-owned subsidiary of Crecor B.V. Both Docor and Crecor were formed as wholly-owned subsidiaries of the Van Leer Group Foundation to promote and participate in commercial activities in Israel.

Investment focus

Health Care, Biotechnology, Pharmaceutical
Funding Round, Series C, Series A
Israel, United States

Portfolio highlights

Check-Cap — The first and only patient-friendly preparation-free test to detect polyps before they may transform into cancer
Ocon Healthcare — OCON Healthcare innovates, develops, manufactures, and commercializes cutting-edge women’s health products based on our patented IUB™ (Intra Uterine Ball) proprietary platform. The IUB™, made from a super-elastic alloy Nitinol, is an ideal carrier for multiple drugs to the uterus to treat a variety of conditions.In addition to our flagshipproduct, the IUB™ Ballerine®, OCON healthcare is developing an innovative pipeline of products utilizing the IUB™ frame for indications such as abnormal uterine bleeding (AUB), heavy menstrual bleeding (HMS), myomas/fibroids, and infertility.
Raziel Health — Raziel Health’s mission is to bring world-class, disruptively less expensive healthcare to everyone, in the comfort of their home. Its unique, integrated system combines easy-to-use technologies that support positive patient experience, enable timely clinical intervention, and meet individual patient goals while using data analytics to supportwellness and disease management.

Triventures is a global, early stage fund that invests in exceptional entrepreneurs. We partner with disruptive ventures with innovative breakthroughs in healthcare and beyond. Our vision is to create a better, healthier future through data driven solutions and cross industry convergence.

Investment focus

Health Care, Medical Device, Medical
Funding Round, Series A, Series B
United States, Israel, Ireland

Portfolio highlights

Grin — Grin is a comprehensive digital orthodontic platform providing teeth straightening for all types of patients with a real local orthodontist. The platform also connects patients with a real orthodontist from the convenience of their smart device. They deliver responsible care from orthodontic specialists in an easily accessible and cost-effectiveway, Grin provides patients quality care that results in an exceptional smile together with all of the modernized convenience that they expect.Grin technology, aligned with a network of local trusted orthodontists, ensures that every patient gets the right care. The platform Grin App and Grin Scope is a patent-pending technology that offers remote monitoring for a variety of orthodontic needs. The Grin experience includes high-quality self-scans with the latest teeth straightening solutions. Practitioners and patients can now use these telemedicine tools to achieve a new, more convenient treatment journey.It was founded by Dr. Adam Schulhof, Pamela Oren-Artzi, and Alon Lipnik in 2019 and is based in New York and Austin.
Cala Health — Cala Health is a bioelectronic medicine company transforming the standard of care for chronic disease. The company's wearable neuromodulation therapies merge innovations in neuroscience and technology to deliver individualized peripheral nerve stimulation. The first indication for Cala Health's wearable therapy is an essential tremor, adisease experienced by more than seven million people and characterized by severe hand tremors. New therapies are under development in neurology, cardiology, and psychiatry. The company is headquartered in the San Francisco Bay Area and backed by leading investors in both healthcare and technology.
TailorMed — Moving Mountains for Patients

Kli Capital is a firm focused on investing in fearless entrepreneurs who are building foundational enterprise technologies and ubiquitous consumer brands. We partner with exceptional founders with unique insights, from inception through all phases of growth.

Investment focus

Health Care, Software, Wellness
Seed, Funding Round, Series A
United States, Israel, Mexico

Portfolio highlights

LexCheck — Transform your contract negotiation process with AI. Review, redline and approve contracts quickly and economically with the power of automation.
VersusGame — VersusGame offers creators and brands the opportunity to cultivate a community with an interactive content solution that rewards knowledge
Cooper — Your parenting lifeline.

TechWald Holding S.P.A. - TWH - Operational Holding Company supporting high growth potential early stage companies committed to develop Healthcare Innovation.We have a key strategy focus on MedTech industry and Medical Technologies - medical devices, equipment, digital devices and services -which can provide benefit and value for Patients, Doctors and Healthcare Systems,and reward Shareholders with a sound and ethical profit

Investment focus

Health Care, Medical, Medical Device
Series A, Series B, Series C
Israel, United States

Portfolio highlights

SoniVie — SoniVie's lead product, TIVUS, is an investigational intravascular treatment that can be performed as part of a routine right heart catheterization for patients suffering from pulmonary arterial hypertension (PAH)
SentiAR — SentiAR is digital health, software device company adding a new dimension to clinical practice in interventional procedures. Spun out of Washington University, we are developing the first 3D visualization platform using real-time holography of the patient's anatomy and catheter location, "floating" over the patients, with a goal toprovide the clinician and patient a faster, safer delivery of care.SentiAR’s mission is to transform the experience for both patient and clinician in interventional procedures with a 3D augmented reality platform featuring real-time holographic visualization of the patient’s actual anatomy, “floating” over the patient.The visualization is fully controllable “hands-free” by the clinician, providing an ergonomic breakthrough for the treatment and analysis of cardiac arrhythmias within an interventional catheter lab environment. SentiAR is developing the platform for eventual FDA submission.
Lymphatica Medtech — Lymphatica Medtech is a medical device development company developing a minimally invasive solution for chronic lymphedema.Lymphedema is the chronic swelling that generally occurs in the arms or the legs.Lymphedema is most commonly caused by the removal of or the damage to the lymph nodes as a part of cancer treatment. It results from ablockage in the lymphatic system, which is part of the immune system. The blockage prevents the lymphatic system from draining excess fluids, and the fluid buildup leads to swelling, infections, and pain.Unfortunately, there is no cure for lymphedema. It can be managed with early diagnosis and diligent care of the affected limb, through daily compression, bandages, and manual drainage sessions. From the moment of the diagnosis, the life of lymphedema patients changes forever.Cancer and cancer-related interventions (i.e. surgery, radiotherapy) are frequent causes of lymphedema occurring both in the upper and lower limbs. Breast cancer survivors are at high risk for developing lymphedema, as well as patients treated for melanoma, pelvic and head and neck cancer or other cancer treatments that require lymph node dissection. Physical trauma can also result in lymphedema, a major cause of lymphatic disease among wounded veterans.Lymphedema is associated with significantly impaired quality of life, skin changes, increased risk of infection and in rare cases lymphedema itself may undergo malignant transformation.Lymphatica offers a permanent solution that will allow patients to regain their normal lifestyle.

Sanara Ventures is an innovation-investment platform, elevating outstanding healthcare-technology companies, from early-stage to global market maturity. At Sanara, They share a vision of an integrated continuum of care supported by accessible advanced healthcare solutions for people around the world.

Investment focus

Health Care, Medical, Medical Device
Seed, Series A, Funding Round
Israel

Portfolio highlights

QTflow Ltd. — A Micro Air Pump Technology: The Future of Thermal Management
CVAid Medical — CVAid Medical develops an innovative AI based stroke detection technological platform.
TailorMed — Moving Mountains for Patients

Mr. Zohar Gilon is a Managing Partner at Tamar Technology Ventures. He has personally invested in over 45 start-ups and has achieved 13 exits. Mr. Gilon has also served as the Transaction Manager for some of Israel's most highly recognized exits and has managed each deal from inception through completion, including pricing and distributions.He has extensive investment experience including activity as an angel investor and an Investment Advisor to the Gilon Group. Mr. Gilon is a private investor in numerous high-technology companies, including affiliates of Radcom Ltd. in Israel. From 1974 to 1993, Mr. Gilon served as the President of various companies representing major U.S. aerospace and electronics corporations. From November 1993 to August 1995, he served as the President of W.S.P. Capital Holdings Ltd. Previously he served, as the Managing Director of Shaked Technologies Ltd. He serves as a Director of HCL CleanTech Ltd., RIT, AVT Ltd., Oberon Media, Inc., Edge Medical, Exlibris, OrSense Ltd., and WisAir Ltd. He served as a Director of RAD Ventures. Mr. Gilon served as a Director of RiT Technologies Ltd. since 1995, Ceragon Networks Ltd. since June 1999, Radware Ltd. from October 2006 to July 2009 and Radcom Ltd. since June 1995. He served as Member of the Supervisory Board of Advanced Vision Technology (AVT) Limited. He served as an Outside Director of Silicom Ltd. since 1994.

Investment focus

Software, Internet, Health Care
Seed, Series A, Series B
Israel, United States

Portfolio highlights

CADY — CADY utilizes AI technology to automate the analysis of electrical schematics
Loora — Unlock your full potential with Loora, your very own AI English tutor. Engage in real conversations with Loora anytime, anywhere, and on any topic!
Annabella — The Electric Breast Pump that mimics a baby's tongue. This technology encourages the release of oxytocin and prolactin hormones, leading to a 50% increase in average milk production.

Emerge is an early stage, Tel-Aviv based Venture Capital firm, partnering with exceptional tech-innovators and helping them do whatever it takes to win.

Investment focus

Software, Artificial Intelligence, Information Technology
Series A, Seed, Series B
Israel, United States

Portfolio highlights

Stigg — Use Stigg's software and APIs to get easy fine-tuned control over what can be priced and packaged separately. Rapidly tweak, test and roll-out your pricing and packaging with no-code.
Chamelio — Chamelio builds intelligent technology for in-house legal teams. We understand that every in-house legal team operates uniquely - shaped by their industry context, company culture, and strategic priorities. Our platform adapts to these distinct characteristics, delivering hyper-personalized workflows that evolve with your team's specific needs.
Xpand (formerly 1MRobotics) — Last mile delivery challenge, solved!

Ak Portfoy is an investment management company that offers services to its customers in mutual funds management, pension funds management.

Investment focus

Information Technology, Software, Financial Services
Seed, Funding Round, Series A
Turkey, United States

Portfolio highlights

heybooster — Heybooster is a provider of analytical tools to ecommerce companies to take better digital marketing decisions.
BRANDEFENSE — Brandefense platform is a proactive digital risk protection solution for organizations. Our AI-driven technology constantly scans the dark, deep, and surface web.
Albert Health — 50% of people with chronic diseases do not take medications as prescribed. Improper medication use, especially for elderly patients, leads to hospitalizations and costs insurers billions of dollars. Current apps in the market are too complicated and difficult to use for the elderly who suffer the most from chronic diseases. Albert is a voice-basedhealth assistant which is accessible through mobile app, Amazon Alexa and Google assistant. Our machine learning algorithms create a unique conversational medication management experience. Elderly patients don’t have to text anymore. They will talk with Albert to manage their medications in an easy and effortless way. Patients can easily track health measurements, keep medical diary and set pill reminder by voice command. Furthermore, “Caregiver Mode” allows family members to manage and monitor their relatives’ treatment remotely. Albert helps elderly patients to take the right dose at the right time and help insurers to have less medical expenses, more satisfied customers.

A Private Equity Investment Company Founded by Leon Recanati in 2003, GlenRock leverages a unique combination of private equity, multidisciplinary in-house expertise, unmatched access to quality dealflow, and a focused but flexible investment strategy to achieve maximum returns.

Investment focus

Software, Cyber Security, Transportation
Seed, Series B, Series A
Israel, United States

Portfolio highlights

Cylus — Cylus, the global leader in rail cybersecurity, helps rail, freight and metro companies avoid service disruption and safety incidents by detecting cyber-attacks in their signaling and control networks, wayside and onboard, before harm happens.
Treetoscope — The first and only commercial device that senses the internal water flow of a plant and directly measures its water consumption and real-time irrigation needs. without extrapolations based on indirect sensing technologies.Treetoscope offers a SaaS irrigation management platform, based on direct plant sensing technology. We tackle one of the mostcrucial challenges farmers face today: water scarcity and irrigation optimization. Our groundbreaking ag-tech enables the unprecedented measurement of real-time actual water use of trees (based on our patented single probe Sap Flow sensor). Through the Treetoscope solution, growers gain great value as a result of the affordability, scalability, and ease of deployment of our technology.
Quris — Quris Technologies is an artificial intelligence (AI) innovator disrupting the pharmaceutical arena.

Mithril is a family of long-term venture capital funds agnostic to sector and geography. We invest and partner with teams who use technology to build valuable and lasting businesses, often in industries long overdue for change.

Investment focus

Software, Health Care, Information Technology
Series C, Series B, Series D
United States, United Kingdom, Israel

Portfolio highlights

Neocis — Yomi, a dental robot, is the next generation in implant surgery that can give patients a better experience, expand your offerings and boost your efficiency
Genetesis — Genetesis is a rapidly growing medical technology company redefining the way patients with a risk of myocardial ischemia and coronary artery disease are clinically diagnosed, monitored and screened.
GreyOrange — GreyOrange is a global company that modernizes order fulfillment through Artificial Intelligence-driven software and mobile robots built together so they cooperate in deciding on and executing warehouse activities that maximize payoffs and minimize tradeoffs to create the highest yield. The company’s always-solving fulfillment operating systemGreyMatter considers predictive and real time data regarding orders, promises, inventory, shipping windows, and resources to orchestrate how workers and robots work together to fulfill the right orders at the right time. GreyOrange experts help organizations master fulfillment in the Age of Immediacy so they keep promises, capture more revenue, and improve the work experience for warehouse employees. GreyOrange has core operations in the United States, Singapore, Germany, Japan and India.

Impact investing in Israeli technology. ZORA is an impact investing fund investing in early-stage Israeli companies solving global challenges in health, education, economic inclusion and the environment.

Investment focus

Health Care, Biotechnology, Internet
Seed, Series A, Convertible Note
Israel, United States, United Kingdom

Portfolio highlights

BiotaX — Microbiome Genomic Analysis Cloud Platform | Biotax.co
Newmoo — Newmoo makes plant-based cheeses and dairy alternatives.
Forsea Foods — Forsea Foods develops cell-cultured seafood through the use of patented organoid technology which allows them to bypass the scaffolding stage of cultivated meat production.

Mr. Yehuda Zisapel (EE,MSc, MBA, DHC) is the founder and president of the RAD-Bynet Group, a leading pioneering association of Israeli companies active in the development, production and marketing of innovative solutions for the data communications industry, and Chairman of RAD. The RAD-Bynet Group grew out of Bynet Data Communications, whichMr. Zisapel founded in 1975 as a small private company that marketed data communications products. Bynet represented major international vendors and was the first to introduce cutting-edge technologies into the Israeli market. Today, the Bynet Group is comprised of eight companies active in both the Israeli and Eastern European markets in such fields as systems integration, cabling, testing, outsourcing, and software development. Following the arrival of Mr. Zisapel’s brother, Zohar, who joined him in 1981, a wide range of industrial activity was spawned from within the newly established RAD, the first of the RAD Group companies. In the years following its successful launch, twenty-four additional independent hi-tech companies were opened to develop, produce and market a wide variety of advanced data communications products.

Investment focus

Medical Device, Medical, Health Care
Funding Round, Series A, Seed
Israel

Portfolio highlights

Carteav — Autonomous Low Speed Vehicle
Rewire — Secure financial services designed to help migrants make cross-border money transfers. Rewire offers great rates, fast delivery, multilingual customer support
Laminate Medical — Laminate Medical Technologies is developing a new, external support device for AV fistulas, to be implanted during the fistula creation surgical procedure. The VasQ Device alleviates wall tension and regulates fistula geometry where an undesired narrowing of the vein and/or frequent blockages of the blood vessels may occur during the firstyear. Use of Laminate Medical Technology’s novel device aims to drive a change in the hemodialysis vascular access treatment paradigm and bring about a significant reduction in the annual fistula failure rate, thereby reducing kidney-failure related complications, re-interventions, and the cost burden of vascular access complications.

HealthpointCapital, LLC is a values-based, research-driven private equity firm that is differentiated by its focus on the musculoskeletal industry. HealthpointCapital has over $800 million of assets under management, including co-investments, resulting in 24 corporate acquisitions for HealthpointCapital's seven platform businesses. The sevenplatform companies, Alphatec Spine, Inc., BioHorizons Implant Systems, Inc., Blue Belt Technologies, Inc., China Rehabilitation Ltd., MicroDental, Inc., Nexa Orthopedics, Inc. and OrthoAccel Technologies, Inc., represent outstanding platforms in some of the key high-growth segments of the orthopedic industry: Robotics, Spine, Dental, Extremities and Emerging Markets.

Investment focus

Medical, Biotechnology, Manufacturing
Series B, Series C, Funding Round
Israel, United States

Portfolio highlights

OrthoSpace — OrthoSpace develops and commercializes simple-to-implant, biodegradable balloon systems for the orthopaedic market. The company aims to create effective solutions for orthopaedics that reduce pain and increase patients’ range of motion while preserving patient bone and joint structures.The company’s first product has the CE mark and iscurrently marketed in Europe. InSpace™ is indicated for patients who suffer from rotator cuff injury, reducing shoulder pain and improving range of motion.
OrthoAccel Technologies — Straighten Your Smile Faster With AcceleDent SoftPulse Technology. Simple To Use, Allowing Braces To Feel More Comfortable With Only 20 Minutes Daily Use!

IAG is an angel investor network that offers access to its affiliates to early-stage venture opportunities. Its members to date have deployed over 22 million Euros to support 41 startups in the series seed/series A stage in many verticals, among which: Medtech, SAAS, e-commerce, Fintech, and high tech at large. Every investment opportunityat IAG is vetted by a professional team together with expert members of the group. Once invested, the company receives the support of up to two Investment champions, who bring their expertise to the table and help them succeed.

Investment focus

Software, E-Commerce, Health Care
Seed, Angel, Series A
Italy, United States, United Kingdom

Portfolio highlights

ALKemist Bio — ALKemist Bio is a biotech startup developing next-generation T cell therapies that target ALK-positive cancers. By reprogramming the immune system, the company aims to overcome resistance and deliver more effective, lasting treatments for solid tumors.
Rubedo Life Sciences — Rubedo Life Sciences is the Premier Longevity Company. Rubedo discovers and develops medicines to keep you biologically young.
Restorative Neurotechnologies — Siamo un'azienda di dispositivi medicali certificati per la riabilitazione cognitiva ed il trattamento di disturbi cognitivi post ictus.

Merz Therapeutics is dedicated to improving the lives of patients around the world with its relentless research, development, and culture of innovation. Merz Therapeutics strives to serve unmet patient needs and realize better outcomes.

Investment focus

Health Care, Therapeutics, Medical Device
Corporate Round
Israel

Portfolio highlights

Vensica Medical — Currently, after surgical removal of tumors found in the bladder, a drug is instilled into the bladder via a catheter. This treatment method is inefficient and ineffective: Urinary bladder cancer has the highest recurrence rates among all types of cancer (70%).Using Vensica’s device, the drug will be instilled in a quick, pain-free proceduresubsequent to the delivery of ultrasound to the urinary bladder. Ultrasound improves the uptake of the drug and its penetration into the bladder wall and is expected to improve the treatment and reduce recurrence rates.

aMoon is a leading healthtech & life sciences venture capital firm.

Investment focus

Health Care, Biotechnology, Medical
Series B, Series A, Funding Round
United States, Israel, Switzerland

Portfolio highlights

Lutris Pharma — Improving anti-cancer therapy by reducing dose limiting side effects
Magentiq Eye Ltd — AI assisted colonoscopy by MAGENTIQ EYE set a new standard of , recognized by the gastroenterology community for its superior performance.
Positive Development — At Positive Development we empower children with autism and their families through the developmental model of autism therapy. Our developmental model respects the individuality of every child on the autism spectrum with treatment based on their strengths and how they process the world around them.

Dov Moran is the Managing Partner of Grove Ventures. He previously worked at modu as the Founder, Chairman, and CEO. Dov Moran attended Technion.

Investment focus

Semiconductor, Hardware, Health Care
Series A, Seed, Series B
Israel, United States

Portfolio highlights

Rapid — RapidAPI is an API Hub that enables over 3 million developers to find, manage, and connect to APIs. RapidAPI lets developers manage all API integrations from one place and gives real-time performance metrics. RapidAPI was founded in 2014 and is headquartered in San Francisco, California.
Triple Jump Medical — Triple Jump Medical is a developer of an insulin pump intended to treat diabetic patients.
Sensible Medical Innovations — Sensible Medical Innovation Ltd. is introducing a breakthrough sensing and monitoring technology providing actionable and accurate data for guiding the management and treatment of several chronic medical conditions representing today’s biggest burden on US and worldwide healthcare budgets.

Clal Biotechnology Industries is a leading Israeli life sciences investment company traded on the Tel Aviv Stock Exchange (TASE: CBI)

Investment focus

Biotechnology, Health Care, Medical
Series A, Funding Round, Series B
Israel, United States

Portfolio highlights

Sight Diagnostics — Combining AI and breakthrough hardware to bring lab-quality CBC results to the doctor's office.
Cadent Therapeutics — Cadent Therapeutics is a precision neuroscience company developing novel medicines that tune and modulate brain rhythms to restore cognitive and motor function in patients with serious neurological disease. The company leverages its precision neuroscience approach combining target specificity, patient selection, drug design and optimization, andnovel quantitative endpoints to create first-in-class molecules to treat movement and cognitive disorders.It was founded in 2010 and headquartered in Cambridge, Massachusetts.
Elicio Therapeutics — Elicio ground-breaking Amphiphile technology is engineering potent vaccines and immunotherapies to defeat an array of aggressive cancers.

Joyance Partners invests in companies that, through science and tech, cultivate joy to improve how we live, focusing on the health and consumer sectors from Pre-Seed to Series A.

Investment focus

Health Care, Biotechnology, Wellness
Seed, Series A, Pre-Seed
United States, Germany, United Kingdom

Portfolio highlights

JOYA — JOYA is the first employee skincare and wellness benefit platform. The company's goal is to provide tailored access to services such as skin cancer screenings, skin condition treatment, anti-aging, acne, and hair loss care from reputable physicians at an accessible cost.
Kyan Health — Prioritise your employees' mental health and well-being with Kyan Health. Our evidence-based solutions address employees' mental well-being, stress at work & boost your workforce productivity.
World Class Health — Access top 1% global healthcare with World Class Health. Superior patient experience & reduced employer spend. Explore our Global Benefits today.

Chartered Opus offers professional market participants (clients such as asset managers) the opportunity to realise “securitised” concepts/products for their own investment or for their customers.

Investment focus

Wellness, Biotechnology, Manufacturing
Series A
Israel

Portfolio highlights

SolCold — We make the sun cool again - Solcold the new environment solutions
Trobix Bio — Trobix Bio is a company that develops and commercializes antibacterial products. It has developed platform technologies called ActiSense and GOTrap for developing high-quality products that remove the threat of antimicrobial resistance.

Laborie is a global medical technology company specializing in Gastroenterology, Urology & Urogynecology, and Obstetrics, Gynecology & Neonatal.

Investment focus

Medical, Health Care, Medical Device
Funding Round, Series A, Corporate Round
United States, Israel

Portfolio highlights

Novocuff — Novocuff is a medical device firm that aims to improve pregnancy outcomes and reduce preterm deliveries caused by PPROM and cervical shortening.
Bright Uro — Bright Uro is an early-stage medical technology company. It is building the next generation of diagnostic devices for Urology. Utilizing advanced hardware, software, and data science can unlock new data streams and offer actionable insight for clinicians.
Vensica Medical — Currently, after surgical removal of tumors found in the bladder, a drug is instilled into the bladder via a catheter. This treatment method is inefficient and ineffective: Urinary bladder cancer has the highest recurrence rates among all types of cancer (70%).Using Vensica’s device, the drug will be instilled in a quick, pain-free proceduresubsequent to the delivery of ultrasound to the urinary bladder. Ultrasound improves the uptake of the drug and its penetration into the bladder wall and is expected to improve the treatment and reduce recurrence rates.

Established in 1997 as the venture arm of XT Holdings, XT Hi-Tech is one of the early investors in Israeli startups. Since inception, we have invested in over 80 companies in various technology categories and at different stages, including Phytech, Checkmarx, Enzymotec, Cymbio, Sofwave, and Lumenis.

Investment focus

Health Care, Medical Device, Agriculture
Seed, Series A, Funding Round
Israel

Portfolio highlights

Cymbio — Connect to hundreds of digital sales channels via Cymbio's automated multi channel e-commerce platform to increase sales & elevate revenue.
BlueThrone — BlueThrone is a Technology-Driven App Appreciation Company that Buys and Grows Great iOS Apps.
NeuReality — NeuReality is a semiconductor start-up that designs AI-as-a-service infrastructure. It addresses the challenges posed by the growing deployment of AI in the cloud, edge, and fog systems.

Tarvenn is an Istanbul-based international investment and advisory firm. Tarvenn has an exceptional knowledge and experience in Turkey, Balkans, Central Asia, North Africa and CIS regions. We build the future with our portfolio, international experience, corporate customers and strategic alliances. Our business is to build yours…

Investment focus

E-Commerce, Software, SaaS
Seed, Pre-Seed, Series A
Turkey, United States

Portfolio highlights

RADAAR — A stunning social media management platform for brands, agencies, and startups that want to engage followers, publish unique content, and measure performance.
Pixa Software — Pixa Software is an e-commerce integration and operations management platform to easily manage order processes.
Madcraft Studios — Enhance your Trials of Osiris performance with our Destiny 2 Trials Carry guides. Learn strategies to secure wins and climb the ranks!

Explore Arkin Capital: A leading multi-asset manager driving strategic investments across health, technology, equity, real estate and more

Investment focus

Biotechnology, Health Care, Therapeutics
Series A, Series B, Funding Round
Israel, United States, Switzerland

Portfolio highlights

Phytolon — Phytolon revolutionizes the way food colors are produce, by Leveraging a novel and sustainable technology for production of healthy food colors in high quality at low costs. Phytolon's mission is to exploit scientific advancement promote human health and environmental sustainability
Honeycomb — Honeycomb (fka Agilius) is the only place where you can buy a condo/apartment building master policy online in less than 3 minutes at a fraction of the cost! Instant, free, no hassle quotes, online everything and up to 40% savings. With all that we're bringing simplicity and transparency to the real estate insurance space for condoassociations (HOAs), building owners, property managers, and developers everywhere. This is what we do. This is all we do.
Nocion Therapeutics — Nocion Therapeutics is a developer of novel pharmaceuticals intended to treat the conditions arising from neurogenic inflammation. The company is developing "nocions" which are a new kind of therapy that selectively affects actively firing nociceptors, enabling patients to provide targeted, robust and sustained relief for the treatment ofserious conditions including cough, itch, pain and inflammation.

ALIVE Israel HealthTech Fund is a pioneer mid-to-late stage HealthTech fund leveraging an exclusive ecosystem.

Investment focus

Health Care, Medical, Biotechnology
Series A, Funding Round, Series B
Israel, United States

Portfolio highlights

Vessi Medical — Vessi Medical is developing an innovative, IP protected cryo spray for hollow & humid organs, a new approach in the treatment of Non Muscle Invasive Bladder Cancer (NMIBC).
Append Medical — A novel transcatheter LAA elimination system
Gina Life — At Nevia bio, we are focused on women's health. Our mission is to use innovative technologies to provide early detection of diseases through vaginal secretions analysis, enabled by Nevia's Machine Learning Platform.

Sofinnova Partners is a leading European venture capital firm in life sciences, specializing in healthcare and sustainability. Based in Paris, London and Milan, the firm brings together a team of professionals from all over the world with strong scientific, medical and business expertise.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
France, United States, United Kingdom

Portfolio highlights

Actithera — Actithera is a molecular radiotherapeutic company that develops radioligand therapies. It translates medicinal chemistry insights into new radioligand therapies (RLTs) and applies various molecular design strategies, including covalent targeting and an isotope-agnostic philosophy, to invent RLTs with significant differentiation and largertherapeutic windows.
One Biosciences — One Biosciences unlocks routine analysis of tumor heterogeneity through AI-powered single-cell technologies, transforming precision medicine.
Galvanize Therapeutics — Galvanize Therapeutics is an energy-based medical device technology that provides therapeutic products and services to deliver healthcare solutions. The company aims to become the global leader in delivering medical technology innovations that drive biological processes to treat a range of diseases, starting with treating chronic bronchitissymptoms, cardiac arrhythmias, and solid tumors.It was formed by Apple Tree Partners in 2022.

Maccabi Fund is an investment fund.

Investment focus

Health Care, Medical Device, Artificial Intelligence
Seed, Pre-Seed, Series A
Israel, United States

Portfolio highlights

AccuLine — AccuLine is a digital healthcare company, which was founded with the vision to saves the lives of millions of people worldwide. AccuLine is developing CORA—a smart, accurate, and easy to use exam for the early detection of coronary artery disease. The clinically validated CORA evaluates a patient's risk of having coronary artery diseasethrough advanced analysis and detection of two newly discovered biomarkers in the heart’s electrical activity. CORA’s early detection will assist in the prevention of sudden cardiac deaths, while lowering costs of cardiovascular related illness.
Rhino Federated Computing — Rhino Health utilizes Federated Learning to improve healthcare AI solutions by providing access to a large, continually updated, distributed dataset from a diverse group of patients, powering AI models that deliver consistent results and improve the standard of care.
Olive Diagnostics — It's About me (IAM) has developed a passive sensor mounted to the rim of the toilet that performs urinalysis every time the end-user urinates. The information is uploaded to a robust data science platform to track existing and progressing conditions. Real-time, actionable notifications will be sent to the end user for proactive medical ornutritional care. Ongoing biomarker tracking for hydration, Alcohol, Pregnancy, Ovulation, Keytones, etc. is used to develop a comprehensive personal user profile.The technology will also be used for pharma and CRO companies to track the usage of drugs. While drug compliance issues plague health care systems around the world, I AM's technology will provide a reliable and continuous solution for tracking when and how people take their medicine or clinical trial drug.Nonindustrial nations will now have home access to urine lab services.

Healthcare innovation wherever it originates.

Investment focus

Biotechnology, Health Care, Medical
Series A, Series B, Series C
United States, Israel, United Kingdom

Portfolio highlights

Moon Surgical — Create the OR of the future, one that is sustainable, efficient, and digitalized.
Artera — Discover the power of Personalized Precision Medicine & AI Cancer Therapy with Artera. Transforming cancer therapy through innovation.
ONL Therapeutics — ONL Therapeutics develops innovative therapeutics to protect and improve the vision of patients with a range of retinal diseases and conditions.

MTIP is a growth capital investor that specializes in scaling up healthtech companies in rapidly expanding global markets. Visit our website!

Investment focus

Health Care, Artificial Intelligence, Medical
Series A, Series B, Series C
United States, United Kingdom, Spain

Portfolio highlights

Hexarad — Hexarad is a radiologist-led radiology company, which combines powerful tech and expert people to provide quick, accurate diagnoses. We have developed the Hexarad Platform, a unique and all-encompassing radiology solution powered by an intelligent allocative efficiency engine.
Caresyntax — Caresyntax is the only enterprise-scale surgical data solution you need to make surgery smarter, safer, and more profitable.
NitiNotes — Nitinotes has developed the EndoZipTM, a fully automated, operator independent gastroscopic suturing system, allowing gastroenterologists as well as surgeons to bring a durable solution to their patients. The procedure creates an effect of stomach volume restriction and motility impair - both are needed to help obese patients reducing weight.

Shimon Eckhouse, Ph.D., is a leading Israeli medical entrepreneur who has founded more than 20 startups including Syneron Medical Ltd., Lumenis Ltd., Ventor and Real-View Imaging. He is the current Chairman of Butterfly Medical Ltd, Active Chairman of Synerion Medical and serves as Executive of Matteris Ltd. Shimon Eckhouse served as the ChiefExecutive Officer of Syneron Medical Ltd. from April 17, 2013 to February 18, 2014. Shimon Eckhouse Co-Founded Colorchip Inc. in 2000 and served as its Chairman from 2003 to January 2004 and as Chief Executive Officer from 2001 to 2003. He served as the Chairman and Chief Executive Officer of ESC Medical Systems since its inception in 1992. He was also a co-founder and Chairman of Ventor Medical Technologies Ltd. He Co-Founded at Navotek Medical Ltd. Mr. Eckhouse took ESC public in 1996 and raised more than $250M in public offerings. He served as Chairman of Syneron Medical Ltd. from May 2004 to May 2013. He worked at Lumenis Ltd. Prior to that, Shimon Eckhouse served as Head of Product Development and Technical Director at Maxwell Technologies in San Diego, California. From 1969 to 1986, he worked at Rafael, Armament Development Authority of Israel as a Scientist, Team Leader and Head of Department and was active in various areas of research and development including lasers and electro-optics. Shimon Eckhouse has been the Founder of Orsense, Ventor, Tulip, Cardiodex, Opticul Diagnostic, C3D and NanoCyte, Inc. Shimon Eckhouse serves as the Chairman of Fluorinex Active Ltd. Shimon Eckhouse serves as the Chairman at Starling Advanced Communications Ltd. since July 2010. He serves as Chairman at OrSense Ltd. He also serves as the Chairman of the Board of Ossense Ltd., Navotek Medical Ltd., and Replicom Ltd. and Edge Medical Devices Ltd. He has been a Director at Syneron Medical Ltd. since May 2004. He serves as a Director of Cardiodex and NanoCyte, Inc. Shimon Eckhouse serves as a Member of Advisory Board of Agate Medical Investments LP and JGV Growth Equity Fund, L.P. Shimon Eckhouse serves as a Director of the Technion Israeli Institute of Technology. He served as a Director of Zend Technologies Ltd. He served as a Director of WideMed Ltd. Shimon Eckhouse has more than 25 registered patents and published more than 50 papers in leading reference journals and conferences. He holds a Ph.D. in Physics from the University of California at Irvine and a B.Sc. in Physics from the Technion Israeli Institute of Technology.

Investment focus

Health Care, Medical Device, Medical
Series B, Series C, Funding Round
Israel

Portfolio highlights

Anchora Medical — Anchora Medical focuses in simplifying of suturing in endoscopic and open surgery applications. The company develops a unique, single-use automatic suturing device for minimal invasive surgery.
Serenno Medical — Serenno Medical is a medical device company creating a urine-output measuring device for the ICU. The company is the developer of a bedside urine output measuring device for hospitalized patients, offering accurate and automatic measurements with low costs, less workload, and improved patient safety.Serenno Medical was founded in 2017 and isheadquartered in Yokne'am Illit, Israel.
RealView Imaging — RealView Imaging is pioneering the field of interactive live holography, creating a new dimension for Augmented Reality applications.

Rapha Capital Management focused on identifying and growing revolutionary ideas in medicine, healthcare and technology before others can see their value. For inquiries, telephone and contact details are used.

Investment focus

Health Care, Therapeutics, Biotechnology
Series A, Series C, Post-IPO Debt
United States, Israel

Portfolio highlights

FIZE Medical — FIZE Medical offers the first platform technology to remotely monitor and manage patients with an indwelling Foley catheter. Learn more about us >>
Imagin Medical — Imagin Medical is a surgical imaging company focused on establishing a new standard of care in visualizing cancer during minimally invasive surgeries. The Company’s initial focus is bladder cancer.The i/Blue Imaging System™ is expected to dramatically improve physicians’ ability to visualize cancerous cells. Working in conjunction withfluorescing imaging agents, this advanced, ultrasensitive imaging technology combines sophisticated opto-electronic functions and near-infrared fluorescence to deliver images far superior to conventional white light systems. Display options include separate blue or white light images, blue and white images displayed side-by-side, or a blending of the blue and white light images into one. Imagin believes the time savings will increase the efficiency of the operating room and potentially reduce healthcare costs by enabling procedures to be performed in the less expensive physician’s office.The i/Blue system was invented by Dr. Stavros Demos at the Lawrence Livermore National Laboratory (LLNL) and validated in collaboration with the UC Davis Comprehensive Cancer Center and Dr. Ralph deVere White, one of the world’s leading authorities on bladder cancer. Imagin now holds the exclusive license to this intellectual property and relocated the final stage of development to the highly-regarded University of Rochester Laboratory for Laser Energetics (LLE) and its affiliated first-class Medical Center. A Research Study using the i/Blue Imaging System prototype was led by Dr. Edward Messing and provided valuable input to the development of the final product for commercialization. Imagin’s engineering team has completed the Proof of Concept Phase and expects the Functional Phase to be completed by end of 2Q2019.As the i/Blue Imaging System becomes established in the urology market, the Company will complete development of the i/Vision Imaging System technology which combines multiple illumination sources into one system. The i/Vision will accommodate the most commonly used fluorescing contrast agents and will potentially enable Imagin to expand into additional surgical specialties.
AsclepiX Therapeutics — AsclepiX Therapeutics represents the next generation of biologics and drug development technology. They use bioinformatics and systems biology methods to design classes of short biomimetic anti-angiogenic (anti-neovascular), and anti-lymphangiogenic peptides. They also use the latest developments in biomaterials and drug delivery to designlong-lasting biodegradable nano and microparticles to deliver these biomimetic therapeutic peptides throughout the body.AsclepiX Therapeutics utilizes its platform technology for indications in ophthalmology, oncology, and for other angiogenesis and lymphangiogenesis-dependent diseases.

We are an early stage venture capital firm dedicated to partnering with inspiring entrepreneurs to build breakthrough companies

Investment focus

Artificial Intelligence, Machine Learning, Software
Seed, Series A, Series B
Israel, United States

Portfolio highlights

ViewNetic — ViewNetic is an AgTech startup developing unique imaging and machine learning technologies for early, pre-propagation detection of pests and diseases in high-value crops.
Infiniplex — Infiniplex is an Israel-based startup whose mission is to utilize routine blood testing to screen for genetic tumor biomarkers and to offer preemptive, preventive, and follow-up cancer screenings at a more accessible and affordable cost. Our goal is to identify common and rare cancer types through a standard, inexpensive blood test that could becarried out as part of routine checkups, leveraging existing laboratory equipment and know-how. We aim to include tumor genomic testing as part of people's standard blood test checkups. The company was founded in 2021 and is based in Yokne'am Illit, Israel.
Intuition Robotics — The AI care companion robot for older adults

Medtronic develops healthcare technology to treat chronic diseases. Its medical technology is providing lifelong solutions for people with chronic pain. The company is committed to improving lives through its medical technologies, services, and solutions. Medtronic has four main business units: the Minimally Invasive Therapies Group, the DiabetesGroup, the Restorative Therapies Group, and the Cardiac and Vascular Group. Medtronic develops and manufactures devices and therapies to treat more than 30 chronic diseases that include heart failure, Parkinson disease, urinary incontinence, Down syndrome, obesity, chronic pain, spinal disorders, and diabetes.Medtronic was founded in 1949 and is headquartered in Minneapolis, Minnesota, United States

Investment focus

Health Care, Medical Device, Medical
Series C, Funding Round, Series B
United States, Israel, China

Portfolio highlights

FIRE1 — FIRE1 and is based in Dublin, Ireland, will focus on developing novel therapeutic devices.
CathWorks — CathWorks is a medical technology company focused on applying its advanced computational science platform to optimize PCI therapy decisions and elevate coronary angiography from visual assessment to an objective FFRangio based decision-making tool for physicians. FFR-guided PCI decision-making is proven to provide significant clinical benefits forpatients with coronary artery disease and economic benefits for patients and payers. The company’s focus is specifically on bringing the CathWorks FFRangio System to market to provide quick, precise, and objective intraprocedural FFRangio guidance that is practical for every case.
Avation Medical — 42 million men and women have symptoms of OAB and incontinence. Vivally can help.

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