Top 50 Life Science VC (Venture Capital) Funds in Canada in January 2025
A list of 50 VC (Venture Capital) funds that invest in Life science startups based in Canada. We rank investors based on the number of investments they made in Life science companies from Canada. We update this investor list every month.Top 50 Life Science VC (Venture Capital) Funds in Canada in January 2025
We transform the most promising oncology innovations into highly competitive opportunities that benefit patients, researchers, investors, and Ontario's economy.
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Investment focus
- Biotechnology, Health Care, Pharmaceutical
- Seed, Funding Round, Pre-Seed
- Canada, United States
Portfolio highlights
- Hyivy Health — Hyivy Health is working on the first smart pelvic health rehabilitation system for patients and the clinicians who treat them.
- HDAX Therapeutics — HDAX Therapeutics novel modality unlocks a never-seen-before binding mechanism to key biological molecules.
- Radiant Biotherapeutics — Radiant Biotherapeutics: Transformative, multi-valent, multi-specific antibody platform: Multabody
We stand proudly on a foundation of deep experience and a demonstrable body of success creating, building, and growing break-out companies.
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Seed, Series A, Series B
- Canada, United States, Israel
Portfolio highlights
- Ability biologics — Ability develops innovative, targeted, immune modulating biotherapeutics to address unmet medical needs in patients with cancer and autoimmune diseases.
- Nomic — Nomic develops a proteomic technology platform designed to understand, detect, and treat diseases with DNA nanotechnology. NPlex's platform and research provides cost-effective measurement of protein data with sample, fits seamlessly within industry cytometers for high-throughput analysis, and development of custom protein panels.It allowsnanotechnology developers and businesses to bring improvement in existing instrument, workflow, and bring automation in the system.
- Radiant Biotherapeutics — Radiant Biotherapeutics: Transformative, multi-valent, multi-specific antibody platform: Multabody
The E-Fund (VANTEC Entrepreneurs Fund VCC Inc.) was established in 2011 to invest in promising new ventures in British Columbia in a wide range of industry sectors. They are focused on co-investing with other angel investors and early-stage venture capital firms in seed-stage companies with high growth opportunities.The E-Fund involvesspecific investors in the investment due diligence process depending on their industry experience and knowledge and their particular technical expertise. It is their goal to become the ‘Go-to Braintrust’ for active and in-depth angel investing.
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Investment focus
- Health Care, Medical Device, Software
- Seed, Pre-Seed, Funding Round
- Canada, China, United States
Portfolio highlights
- Frontly — Build custom apps with no code
- Care2Talk — Care2Talk is a video call mobile app for senior citizens that is secure, fast, and easy to navigate with 7-day battery life.
- VoxCell BioInnovation — Creating an extraordinary line of solutions for the drug development industry and the field of Oncology research.
Real Ventures is an early-stage venture firm focused on serving daring entrepreneurs with the ambition to create successful, global companies. Since 2007, Real Ventures has dedicated itself to building the Canadian startup ecosystem on the belief that people, not money, build game-changing companies. Real Ventures provides stage-specific guidance,mentorship, and access to networks and resources to fast-track founders’ personal and company growth. Real Ventures manages $325 million across five funds and its active portfolio of 100+ companies is currently valued at $10 billion. www.realventures.com
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Investment focus
- Software, Artificial Intelligence, Machine Learning
- Seed, Series A, Series B
- Canada, United States, United Kingdom
Portfolio highlights
- dcbel — dcbel's mission is to deliver energy that lets people live a life without compromise.dcbel™ (formerly known as Ossiaco) sits at the nexus of residential solar power, electric vehicle charging, the smart home, and customer-centric utilities. The dcbel team has a proven history of rethinking energy distribution for everything from largeutility customers to distributed energy resource providers.dcbel's AI-driven sustainable technologies enable people to leverage solar energy to power their cars, their homes, and their lifestyles.dcbel has numerous worldwide patents in power electronics and power conversion and is backed by a number of globally respected investors.
- Nomic — Nomic develops a proteomic technology platform designed to understand, detect, and treat diseases with DNA nanotechnology. NPlex's platform and research provides cost-effective measurement of protein data with sample, fits seamlessly within industry cytometers for high-throughput analysis, and development of custom protein panels.It allowsnanotechnology developers and businesses to bring improvement in existing instrument, workflow, and bring automation in the system.
- BioIntelligence Technologies — Industrie 4.0 - Enabling intelligent biomanufacturing: from R&D to production. Real-time optimization of cell cultures and fermentations.
Value-added investors for innovative entrepreneurs.
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Investment focus
- Software, Health Care, Artificial Intelligence
- Seed, Funding Round, Angel
- Canada, Spain, United States
Portfolio highlights
- Hexoskin (Carré Technologies) — Hexoskin is the leader in Smart Clothing, Software & AI Data Analytics. The Hexoskin Smart Shirts are clinically validated for continuous ECG, HRV, Respiratory, Activity, Sleep & Stress monitoring. The Hexoskin Smart Garments are used by sports scientists, healthcare, defense, aerospace & research professionals.
- Workstaff — Simplify workforce management, staff scheduling and time tracking with the Workstaff software and mobile app. Start for free and save time today!
- HDAX Therapeutics — HDAX Therapeutics novel modality unlocks a never-seen-before binding mechanism to key biological molecules.
Apjohn Ventures Fund is a new venture capital firm based in Kalamazoo, Michigan established to invest primarily in early stage life sciences companies across the Midwest. The goal of the Fund is to provide investors with superior financial returns by making equity investments in innovative life sciences companies with sustainable and outstandinggrowth potential.
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Investment focus
- Health Care, Biotechnology, Life Science
- Series A, Series C, Funding Round
- United States, Canada
Portfolio highlights
- Tetra Discovery — Leaders in innovative memory loss treatments. Developing drugs to treat Alzheimer's, Depression, and Brain Injury.
- Tetra Therapeutics — Leaders in innovative memory loss treatments. Developing drugs to treat Alzheimer's, Depression, and Brain Injury.
- Sierra Oncology — Sierra Oncology is late-stage clinical drug development biopharmaceutical company on a mission to deliver targeted therapies that treat rare forms of cancer.
Radical Ventures invests in the future of how we live, work and play, partnering with founders who understand the transformational power of AI.
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Investment focus
- Artificial Intelligence, Software, Information Technology
- Seed, Series A, Series B
- United States, Canada, United Kingdom
Portfolio highlights
- Muon Space — Earth intelligence for a Safe and Resilient World.
- World Labs — World Labs is an AI startup that can analyze visual data with comprehension akin to a person's, a substantial advancement above existing capacities.
- Synex Medical — Synex Medical develops non-invasive blood testing technology. This portable device will allow users to monitor metabolite concentrations without having to penetrate skin. They use a miniaturized magnetic resonance system to detect blood metabolites. The system only consists of magnets and radio waves, meaning there are no negative health effects.
A voice in setting the standards, best practices and processes in health technologies ; a privileged access to 190+ members
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Investment focus
- Health Care, Medical Device, Biotechnology
- Seed, Funding Round, Series A
- Canada
Portfolio highlights
- Eli — Hormone testing redesigned so you can monitor anytime, anywhere.
- LUCID — LUCID curates and creates personalized therapeutic music using biometrics, psychometrics, and AI to improve mental health and wellness.
- HALEO Clinic — HALEO is an online insomnia clinic that fits in your pocket
MaRS Innovation (MI) is a commercialization engine that integrates, centralizes and accelerates time to market of the discovery and intellectual property assets from its 15 world-class research institutions. MI’s discovery and innovation pipeline is derived from $1 billion in annual R&D funding. Created as a not-for-profit organizationthrough the Government of Canada’s Center of Excellence for Commercialization and Research program (CECR), MI has raised $50 million from federal and provincial governments, member institutions and industry partners. MI’s vision is to transform the Toronto-based research enterprise into one of world’s most successful commercialization clusters.Through detailed, market facing due diligence, MI identifies opportunities from Canada’s largest academic cluster for further development and commercialization through project management, intellectual property management, investment and technology development. By crossing the innovation gap, MI transforms these opportunities into successful high-value licensing transactions and financeable start-up companies.
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Investment focus
- Health Care, Biotechnology, Software
- Pre-Seed, Seed, Funding Round
- Canada, United States
Portfolio highlights
- HDAX Therapeutics — HDAX Therapeutics novel modality unlocks a never-seen-before binding mechanism to key biological molecules.
- Damona Pharmaceuticals — Damona Pharmaceuticals is a pre-clinical pharmaceutical company treats and prevents cognitive deficits in a variety of brain disorders and during aging.
- Radiant Biotherapeutics — Radiant Biotherapeutics: Transformative, multi-valent, multi-specific antibody platform: Multabody
iGan Partners is one of Canada's largest healthcare-focused venture capital firms, investing across North America. We provide capital and expertise to scale innovative healthcare solutions.
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Investment focus
- Health Care, Software, Medical
- Seed, Series A, Funding Round
- Canada, United States, United Kingdom
Portfolio highlights
- Okadoc — The quickest way to book from thousands of doctors, manage your appointments and attend video consultations. All online: healthcare in your hands.
- Segmed — At Segmed, our platform Insight democratizes healthcare data. We work with data partners to ensure secured, anonymized medical data for AI developers.
- RetiSpec — RetiSpec is a medical imaging company using advanced AI for the detection of neurodegenerative diseases through hyperspectral imaging of the eye.
BDC Venture Capital is a major venture capital investor in Canada, active at every stage of the company's development cycle, from seed through expansion, with a focus on technology-based businesses that have high growth potential and that are positioned to become dominant players in their markets. The company helps create and develop strongCanadian businesses through financing, consulting services and securitization, with a focus on small and medium-sized enterprises.BDC Venture Capital has been involved in venture capital since 1975 and has to date invested in more than 400 companies involved in the areas of Life Sciences, Telecommunications, Information Technology and Advanced Technologies.
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Investment focus
- Software, Information Technology, Artificial Intelligence
- Series A, Funding Round, Seed
- Canada, United States, Japan
Portfolio highlights
- KOHO Financial — Open an everyday spending account online with instant cash back & premium rewards. Join over 1.5M Canadians using KOHO's prepaid Mastercard to spend, save, build and borrow. Sign up in minutes!
- Healthkind — Enabling healthcare teams to deliver personalized care at scale.
- Planetary Technologies — info@planetarytech.com
Desjardins Capital makes it easy to grow your business with financial and strategic support. Investment capital and venture capital can help you meet your business goals.
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Investment focus
- Software, Information Technology, Manufacturing
- Funding Round, Seed, Series A
- Canada, United States
Portfolio highlights
- Inscora — Inscora provides automated cyber risk assessment and sales enablement tools for cyber insurance brokers.
- Local Logic — Local Logic provides industry-leading location intelligence technology. Helping the real estate industry make better decisions since 2015.
- Picketa Systems — Picketa Systems equips agribusinesses with Analysis Stations to perform plant tissue analysis in seconds
Fonds de solidarité FTQ is a private equity and venture capital firm specializing in investments in start-ups, early venture, mergers, business acquisitions, management buyouts, market development project or a buyout, financing for new programs, organic growth and cash flow, growth and expansion financings, development capital, business succession,financial restructuring, business transition financing, family and non-family buyout, consolidations, turnaround, and leveraged management buyouts. It also invests in new markets, product and business line developments, market diversification, interim financings, new product marketing, additional working capital, purchase of tangible and intangible assets, equipment modernization, equipment purchases or upgrades, and integrator projects. The firm has regional funds that do not invest in retail, real estate, farming, biotechnology, and financial services. Fonds de solidarité FTQ invests in small and medium-sized businesses. It typically invests in export projects, forest products, productivity improvement, natural resources, aerospace, agri-food, wood, pulp and paper, chemicals, construction and construction materials, printing, transportation equipment and automobiles, transportation services, furniture and fixtures, combinatorial chemistry and other lead generating technologies, mining and exploration, social economy, textiles, plastics, life sciences, business services, telecommunications, distribution and consumer goods, environment, equipment and machinery, financial services, information and communication technology, metal products, recreational tourism, and culture sectors. Within the culture sector, Fonds de solidarité FTQ seeks to invest in pre-production and creative projects, production projects, infrastructures and services, post-production projects, distribution, and broadcasting and multiplatform broadcasting. Within the environment sector, it invests in waste management and energy conversion for residual waste; air treatment and reduction of greenhouse gas emissions; processes to reduce industrial energy and water consumption; water treatment; and soil rehabilitation and decontamination (metals and organic compounds). Within the life sciences sector, Fonds de solidarité FTQ focuses on services for the biopharmaceutical industry; nutraceuticals and cosmeceuticals; diagnostics and medical supplies and equipment; biopharmaceuticals and generic drugs; biotechnology, and animal health. Within the tourism sector, it focuses on urban tourism, nature tourism, resort type tourism, and local tourism for Quebecers, and in the textiles sector it invests in companies engaged in development and production of specialty textiles as well as development of industrial applications for the construction, transportation, health and safety, and work apparel industries. Fonds de solidarité FTQ prefers to invest in Quebec and in companies impacting the Québec economy. It focuses on investing in the following regions- Abitibi –Témiscamingue, Bas Saint Laurent, Chaudière-Appalaches, Côte-Nord, Estrie, Gaspésie Îles-de-la-Madeleine, Lanaudière, Laurentides, Laval, Mauricie - Centre-du-Québec, Montérégie, Nord-du-Québec, Outaouais, and Saguenay-Lac-St-Jean. Fonds de solidarité FTQ seeks to invest in projects of $3 million or more and also provides loans of up to $ 2 million. It invests in companies in business succession sector having minimum capitalization of $500,000 and EBITDA of over $35.5 million in case of majority interest; equipment and machinery sector with average investment in excess of $3 million; environment sector with funding needs of more than $500000; financial services sector having net assets between $20 million and $50 million in equity; metal products sector having annual sales of over $5 million and financing needs of at least $2 million; and printing sector having investment needs of over $1 million. In the information technology sector, Fonds de solidarité FTQ seeks to invest $2 million as initial investments while total investments can be more than $10 million. It invests in the form of equity financing (common or preferred shares) and unsecured debt requiring no collateral (debenture). Fonds de solidarité FTQ can take both a minority interest including an equity stake of up to 49 percent as well a majority interest in its portfolio companies in case of business succession financing. It seeks a minority stake for the portfolio companies in the equipment and machinery sector. It typically holds its investments for a period of five to ten years in case of equity financing and for more than ten years in case of business succession financing. Fonds de solidarité FTQ began operation on June 23, 1983. It has its headquarters in Montreal in Canada with additional offices in the same city and Quebec in the same country.
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Investment focus
- Manufacturing, Biotechnology, Software
- Funding Round, Series A, Series B
- Canada, United States, Israel
Portfolio highlights
- Energir — Energir is a energy producer located in Montreal Canada.
- KisoJi Biotechnology — KisoJi is a leading next-generation antibody company developing multi-specific antibodies to address difficult targets in oncology and other diseases
- TTI Air Conditioning Heating — TTI Air Conditioning Heating is a wholesaler of air conditioning and heating products for photovoltaic solar panels and central heat pumps.
At Sustainable Development Technology Canada (SDTC), they fund Canadian cleantech projects and coach the companies that lead them as they move their ground-breaking technologies to market.SDTC’s support of cleantech translates into jobs, growth, and export opportunities for Canadian companies, as well as economic, environmental and healthbenefits for all Canadians. They are independent but don’t work alone. A big part of their role is building and sustaining networks of partners and stakeholders from private industry, academia and governments, at home and abroad. They operate at arm’s length and receive funding from the Government of Canada.
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Investment focus
- Manufacturing, Energy, Software
- Grant, Seed, Funding Round
- Canada, United States, Brazil
Portfolio highlights
- Niricson — Niricson Software has developed a proprietary damage assessment software platform paired with a patent-pending drone-based data collection technology that helps infrastructure owners inspect their structures (e.g. hydro dams) in a way that is more accurate, five times faster, and 50% more cost-effective. Niricson is differentiated by its ability toautomatically detect and quantify not only surface damage, but also subsurface damage.
- ZeroIN — For ingredient manufacturers seeking to enhance the taste profile of their sweeteners, ZeroIN develops technology to produce next-gen sweeteners with the same bulk, sweetness, and taste as sugar but no aftertaste.
- Marine Thinking — Marine Thinking is focused on redefining the marine industry through artificial intelligence (AI) and robotic technologies. It gathers data from marine environments and fish farms using remotely operated vehicles, or ROVs and analyze it using artificial intelligence.
Yaletown Partners specializes in investing in software, data, and device technologies. It invests in technology companies that improve industry and enterprise productivity and sustainability, to help accelerate their growth, shorten exit timeframes, and accomplish strong exit premiums.With offices in Vancouver, Calgary, Montréal, and a growingpresence in Toronto, Yaletown is led by a national team that contributes almost 100 years of technology-industry experience and a network of extensive industry relationships.
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Investment focus
- Software, Enterprise Software, Information Technology
- Series A, Series B, Seed
- Canada, United States, Belgium
Portfolio highlights
- ClimateAI — Build climate resilience with accurate insights and actionable recommendations that will give you a competitive edge.
- Inverted AI — Inverted AI, a spinout from UBC, is building a proprietary software system that predicts human driving behavior and is using it to build bots imitating human drivers for simulators where self-driving cars are trained. Its core technology utilizes probabilistic programming and provides a crucial ingredient needed to make self-driving cars'level 4' and above a reality.
- InnerSpace — InnerSpace is the fastest way to transform your business and power the hybrid workplace strategy. Transforming workplace experience with insights into how people use a space and create innovative solutions that drive revenue and improve operations to hybrid offices.
Enabling passionate, committed SaaS entrepreneurs to accelerate growth.
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Investment focus
- Software, SaaS, Information Technology
- Series A, Series B, Funding Round
- United States, Canada
Portfolio highlights
- ACTO — ACTO is an omnichannel education platform for life sciences companies. ACTO is an AI-powered SaaS platform built for life sciences that uses mobile experiences and agency partnerships to give learners all the tools they need in one intuitive cross-platform app, and give leaders powerful admin tools with engagement data in one command center.
- Kahuna Workforce — Skills management software that helps you assess and manage frontline and technical workers, ensure safety and compliance, and make more strategic decisions.
- Cecilian Partners — Best-in-Class Proptech Solutions: Real estate management, mapping, and development software to support property developers, home builders & realtors.
StandUp Ventures is a venture capital firm investing in female-founded companies in the B2B software and digital health sector.The firm is led by a team of experienced investors who have assembled a diverse advisory committee. The advisory committee is comprised of successful founders, venture investors, and other strategic mentors who willprovide high-touch support to the entrepreneurs. StandUp Ventures catalyzes strong deal flow across Canada from its network and syndicate seed rounds with Angels and US VCs.
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Investment focus
- Software, Artificial Intelligence, Machine Learning
- Seed, Series A, Series B
- Canada
Portfolio highlights
- Indiegraf — Indiegraf provides technology and services purpose-built for small and startup news publications. Get everything you need to grow your audience and multiple revenue streams - all in one place.
- MaxRetail — Max Retail helps you sell unsold inventory to 80+ million end consumers, buy immediates on our exclusive retailer marketplace and more.
- Mercator AI — Our mission is to give business developers more time to do what they do best, and support them with the insights they need to have informed and productive conversations. We mine and analyze millions of construction data points across the project lifecycle so that our customers can confidently find and qualify projects and partners faster.Mercator is used by Architecture, Engineering, Construction, Real Estate, and Manufacturing companies to inform strategic and tactical decision making.Mercator AI is a privately held company that has recently closed a pre-seed round.
Innovate Calgary is a central innovation hub at the University of Calgary. See our programs and fundings and learn more about our innovation hubs here.
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Investment focus
- Health Care, Medical, Medical Device
- Seed, Pre-Seed, Funding Round
- Canada, United States
Portfolio highlights
- MACH32 — MACH32 is a medical device startup that develops innovative solutions for new and longstanding medical problems.
- InventoRR MD — InventoRR MD focuses on commercializing groundbreaking trauma and general surgery devices that improve patient recovery outcomes, simplify procedures for doctors, and reduce costs for healthcare organizations.
- Difinity Solutions — Difinity Solutions is specializing in the development of medical devices and technology solutions.
Hazelview Ventures provide entrepreneurs with a unique opportunity to refine, scale, and showcase product and service capabilities.
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Investment focus
- Software, Aerospace, Architecture
- Seed
- Canada
Portfolio highlights
- Xaba — Xaba develops intelligent automation solutions, materials and processes to enable a world of sustainable manufacturing.
- Lamarr.AI — Saving Energy Through Automated Building Exterior Inspection AI-powered envelope diagnostics to accelerate the transition to Net Zero buildings. Contact Us About Lamarr.AI Defining pathways for future cities by developing technology innovations Lamarr.AI entered the market in 2023 as the product
- Augmenta — Design sustainable, code compliant and fully constructible buildings in hours.
Canada's leading nationwide pre-seed venture fund.
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Investment focus
- Software, Information Technology, Artificial Intelligence
- Seed, Pre-Seed, Series A
- Canada, United States, Israel
Portfolio highlights
- Revyl — Revyl is an observability platform that helps teams identify and resolve bugs before they reach production. It offers real-time monitoring and insights, allowing developers to catch issues early in the development process. With features such as error detection and performance analytics, Revyl enhances software reliability and improves the overalluser experience.
- Nmbr — Nmbr focuses on streamlining organizations' payroll processes by providing customizable software solutions. Nmbr approach not only simplifies payroll management but also allows businesses to tailor the system to their specific needs, ensuring compliance and efficiency.
- Platformatic — OpenSource Platform for ...
Golden Ventures is a leading seed-stage venture capital fund, based in Toronto and investing across North America. We back bold teams and their transformative ideas.
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Investment focus
- Software, Artificial Intelligence, Information Technology
- Seed, Series A, Series B
- Canada, United States, Japan
Portfolio highlights
- Deck — Open Data API accessing Energy, Water, Government and many more data verticals to power sustainability, credit check, accounting, bill payments and many more use-cases. Start building now with Deck's self-serve platform.
- Nmbr — Nmbr focuses on streamlining organizations' payroll processes by providing customizable software solutions. Nmbr approach not only simplifies payroll management but also allows businesses to tailor the system to their specific needs, ensuring compliance and efficiency.
- CYRISMA — The strength of Data Spotlite's SaaS solutions CYRISMA is not simply discovering and reporting Cyber Risk but RESOLVING those risks. This solution offers a single interface to identify, report, summarize and manage risks. Traditional methods of cyber risk management rely on a collection of separate and costly solutions that generate a mountainof disconnected reports that must be manually addressed. Many organizations simply don’t have the resources or manpower to reach their compliance goals as a result.
Founded 16 years ago in 1997, it is the only Angel Capital Forum ™ in Canada that introduces emerging companies to private equity Angel Investors. Presenting companies have raised over $35 million directly through the Forum. Read this third party blog comment and video overview. Since 1998, it has offered Investor Ready ™ workshops for companies& investors.As the oldest & largest angel network in Western Canada with 50+ investors (from Vancouver, Calgary, Edmonton, Kelowna, Victoria, Bellingham and Seattle), they are supported by leading organizations in BC and belong to Canada's National Angel Capital Organization and US's Angel Capital Association. Their private meetings are exclusive to only pre-registered Investors, selected Companies and Sponsors. Regretfully no observers except volunteers.
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Investment focus
- Biotechnology, Health Care, Software
- Seed, Angel, Pre-Seed
- Canada, United States
Portfolio highlights
- Cuboh — Cuboh consolidates all your food delivery orders in one tablet and integrates them with your restaurant's POS system. Cuboh, online ordering on autopilot.
- Truss — Send and receive business payments online with no limits, no percentage fees and no bullsh*t. Bring your business payments into the 21st century.
- Orbitless Drive — ORBITLESS, we are pioneering the future of gear systems with our groundbreaking drivetrain technology
LVL1 Group is a private investment management firm, operating across different asset classes and geographies. We were founded with entrepreneurial spirit at our core, with a natural passion for venture investing, working closely with founders to forge meaningful strategic relationships and helping them to succeed. We are not bound by mandates andinvestment periods, which allows us to be flexible and opportunistic. We look for companies that aim to make a strong global impact, particularly in Online Travel, Gaming, eSports, Content and Community Platforms.
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Investment focus
- Software, Health Care, Apps
- Seed, Series A, Series B
- Canada, United States, United Kingdom
Portfolio highlights
- Appetito — Buy all your groceries and household essentials from your online supermarket. Order from the comfort of your home at your finger tips.
- GRACIA.AI — AI-powered ultra-photorealistic volumetric videos for VR, MR and more
- Jiffy Grocery — Grow your business with Jiffy SaaS platform which includes app/website, picking, delivery, supply chain & replenishment services
The Ontario Centres of Excellence invests in projects and people to accelerate industry R&D to impact the Ontario economy through the commercialization of leading edge research.OCE invests in- Industry-Academic collaborative research- Commercialization of academic research through licensing and spin off companies- Early stage seedfinancing of start-ups- Skills development for high quality personnelThe Ontario Centres of Excellence is a not-for-profit corporation founded in 1987. Core funding is provided by the Ontario Ministry of Research and Innovation
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Investment focus
- Software, Information Technology, Health Care
- Seed, Grant, Pre-Seed
- Canada, United States
Portfolio highlights
- Uride — Welcome to Uride - your reliable and affordable ridesharing service with a community-focus. Enjoy the ease of quick pickups, lower fares, and a user-friendly app designed to make your travels smoother. Start riding today!
- FluidAI Medical — Real-Time Monitoring for Anastomotic Leaks with Origin, by FluidAI. Early data shows FluidAI's Origin can detect leaks an average of 1.6 days earlier.
- Novel Biotechnology — Novel Biotechnology is building high-throughput bacterial platforms for the biotech industry, with a focus on plasmid DNA manufacturing.
Pfizer Venture Investments is a corporate venture capital firm that invests in areas of current or future strategic interest to Pfizer. It aims to remain at the forefront of life science advances. It identifies and invests in emerging companies that are developing transformative medicines and technologies that have the potential to enhance Pfizer’spipeline and shape the future of its industry.
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Series B, Series A, Series C
- United States, United Kingdom, Switzerland
Portfolio highlights
- Enara Bio — Enara Bio is a science-led company targeting the T-cell/cancer cell interface (the “immune synapse”) to develop new targeted cancer immunotherapies designed to treat a broad patient population. Enara Bio focuses on discovering and developing therapeutic cancer vaccines utilizing novel antigens derived from endogenous retroviral (ERV)-relatedDNA sequences.
- TRex Bio — TRexBio is a discovery stage biotechnology company leveraging cutting-edge computational biology tools, a focus on human tissue, and expertise in immunobiology to develop revolutionary therapeutics for cancer and inflammatory diseases. Our powerful ‘deep biology’ discovery engine maps human tissue Treg behavior to disease processes, allowing us toidentify and characterize novel targets for therapeutic intervention. Leveraging this platform, we are building a broad portfolio of novel therapies that modulate the immune system to restore human tissue immune homeostasis.
- ImmunOs Therapeutics — ImmunOs Therapeutics AG is a clinical-stage biotechnology company focused on discovering and developing next generation and novel human immunomodulatory proteins with a role in both innate and adaptive immunity.Their mission is to develop the next generation of novel therapeutics that will improve the lives of patients with serious disease.
Ontario Centre of Innovation provides a preeminent research-to-commercialization vehicle in Ontario
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Investment focus
- Health Care, Medical Device, Financial Services
- Seed, Pre-Seed, Grant
- Canada, United States
Portfolio highlights
- Talin — Supercharge your recruting process with Talin's AI powered tools.
- Mesosil — Mesosil develops responsive antimicrobial materials to prevent infection at the medical device-tissue interface, with lifetime length of effect. Our technology is ideally suited for dental restoratives and dental implant surfaces. The result is greatly improved patient outcome with no change to practitioner workflow, reducing the likelihood ofrecurrent caries and detachment of dental restorations, or peri-implant wound infection that could result in implant loss and implant revision.
- HDAX Therapeutics — HDAX Therapeutics novel modality unlocks a never-seen-before binding mechanism to key biological molecules.
We angel invest in founders who will improve the lives of millions. Based in Toronto, Canada.
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Investment focus
- Biotechnology, Health Care, Software
- Seed, Pre-Seed, Angel
- Canada, United States
Portfolio highlights
- ALT TEX — ALT TEX is creating sustainable textiles regenerated from post-industrial waste.
- Spare — Spare is your all-in-one mobility operations platform, designed to provide an end-to-end platform ecosystem for operating modern paratransit and microtransit systems.
- Mayday — Time is your most valuable asset. Make sure you're spending it wisely.
Innovacorp is an early-stage venture capital firm that helps knowledge-based startups commercialize their technologies in the global marketplace. It invests in early stage Nova Scotia entrepreneurs, combining venture capital with business mentoring and incubation facilities.
Innovacorp was established in 1995 and based in Halifax, Canada.
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Investment focus
- Software, Information Technology, Health Care
- Seed, Grant, Funding Round
- Canada, Australia, United States
Portfolio highlights
- Bright Breaks — Bright offer on-site and virtual amenities for companies and employees. whether your team is on-site, working from home, or in between.
- OVERGantt — With over 25 years in project management, OVERGantt provides cutting-edge software designed to keep you ahead of the game. Enquire today!
- Planetary — Planetary develops ocean-based carbon removal technology to accelerate the natural carbon cycle. Planetary’s system purifies the mountains of alkaline rock waste left behind by large-scale mining operations, extracting the alkalinity from the rubble and putting it in the ocean, thus accelerating the carbon transition and rebalancing oceanchemistry.Planetary Technologies is on a mission to remove 1 billion tonnes of carbon dioxide from the atmosphere by 2035.
Versant partners with exceptional entrepreneurs to build and fund breakthrough biotechnology companies around the globe.
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Investment focus
- Biotechnology, Health Care, Medical
- Series A, Series B, Series C
- United States, Switzerland, Canada
Portfolio highlights
- 858 Therapeutics — 858 Therapeutics is a stealth company specializing in the area of healthcare services, pharmaceutical, and biotechnology. The company was founded in 2019 and is headquartered in San Diego, California, USA.
- Antag Therapeutics — Antag Therapeutics operator of a biotechnology company intended to develop metabolic and anti-obesity therapeutic drugs.The company specializes in the development of peptide-based GIP receptor antagonist in order to monitor dietary-related metabolic diseases through the infusion, enabling the healthcare industry to decrease blood flow and lipiduptake in adipose tissue in an efficient manner.
- Pep2Tango Therapeutics — Pep2Tango Therapeutics is a biotechnology company that offers superior unimolecular multi-receptor drugs for obesity and related disorders.
Afore Capital backs product-centric founders at the pre-seed stage exclusively. The investment team brings 16 years of founding product experience (Android and Twitter) and 7 years of institutional investing experience (Founder Collective and Foundation Capital). Their sweet spot is the ~$1M pre-seed round, where they can lead the round as aninstitutional investor alongside high value angels.
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Investment focus
- Software, Artificial Intelligence, Health Care
- Seed, Pre-Seed, Series A
- United States, Canada, India
Portfolio highlights
- Grove — AI-accelerated Participant Relationship Management (PRM) for Clinical Research
- New Lantern — New Lantern provides cutting-edge AI-powered cloud-native PACS solutions for healthcare providers, enabling faster and more accurate radiology diagnostics.
- Zephyr — We make it easy for teams to find, watch, and analyze every event for every player for every game.
WUTIF Capital (VCC) Inc. is a novel angel fund that co-invests with angel investors in promising new technology ventures in British Columbia. WUTIF was formed in mid-2003 and made its first investments in late 2004.
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Investment focus
- Software, Health Care, Medical Device
- Seed, Pre-Seed, Series A
- Canada
Portfolio highlights
- Levr.ai — Levr.ai supercharges your team with easy to implement tools that increase conversion, save time and provide a better experience for everyone.
- A&K Robotics — A&K Robotics | Autonomous Vehicle Systems
- Polar Beer Taps — Polar Beer Taps Permafrost V3 system is leading the way in the future of portable beverage serving. They can provide reliable, high-quality commercial draft systems to any location, which elevates any event.
Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that aredeveloping transformative new modalities and platforms to meaningfully improve human health.
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Investment focus
- Biotechnology, Health Care, Therapeutics
- Series A, Series B, Series C
- United States, France, Canada
Portfolio highlights
- Umaro Foods — Umaro Foods specializes in developing a plant-based protein source from ocean-farmed seaweed.
- TwoStep Therapeutics — TwoStep Therapeutics is developing novel tumor-targeting therapeutics for solid tumors.
- Bright Peak Therapeutics — Bright Peak is a biotech company that develops a portfolio of immunotherapies for the treatment of cancer and autoimmune diseases. At Bright Peak, they are creating innovative cytokine therapeutics that are uniquely engineered to precisely control and expand desired biological properties.
OCV Partners is a Los Angeles based venture capital firm that invests in companies with differentiated technologies in compelling target markets.
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Investment focus
- Biotechnology, Therapeutics, Health Care
- Series B, Series A, Funding Round
- United States, Canada, United Kingdom
Portfolio highlights
- Verlume — Subsea energy storage and remote power generation for the energy transition, low carbon offshore operations and zero emission hydrocarbon production.
- GUIDEcx — GUIDEcx helps you make a good first impression on your customers. A smooth, transparent customer onboarding process is key to putting your best foot forward.
- Akebia Therapeutics — Fully integrated renal biopharmaceutical company with a late stage product in global Phase 3 clinical development and a commercially available medicine.
NSERC is a Canadian government agency that provides grants for research in the natural sciences and in engineering.
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Investment focus
- Health Care, Biotechnology, Education
- Grant, Seed, Funding Round
- Canada
Portfolio highlights
- Centennial College — We have over 400 diploma, degree, and certificate program offerings to help launch your career. With more accredited programs, pioneering research projects and partnerships that offer semesters or placements abroad. An education rooted in the principles of global citizenship, equity and social inclusion. All at Centennial College.
- FemTherapeutics Inc. — FemTherapeutics Inc. is developing the world's first customizable gynaecological prosthetic for the treatment of pelvic health conditions.
- FluidAI Medical — Real-Time Monitoring for Anastomotic Leaks with Origin, by FluidAI. Early data shows FluidAI's Origin can detect leaks an average of 1.6 days earlier.
BIOFUND SpA, established by Fondazione Monte dei Paschi, Bank Monte dei Paschi , Finanziaria Senese di Sviluppo e Fidi Toscana, provides the initial seed capital for companies located in the incubator of Toscana Life Sciences in Siena.
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Investment focus
- Genetics, Medical, Health Care
- Funding Round, Seed
- Canada, Denmark, Russian Federation
Portfolio highlights
- Exiqon — Exiqon operates in two business areas: Life Sciences and Diagnostics. Exiqon Life Sciences, a leading provider of flexible solutions for RNA analysis. Exiqon’s research products are used by academia, biotech and pharmaceutical companies around the world to make groundbreaking discoveries about the correlation between gene activity and thedevelopment of cancer and other diseases. Exiqon Diagnostics collaborates with pharmaceutical and diagnostic companies to develop novel molecular diagnostic tests for early detection of diseases which can help physicians make treatment decisions based on the tools developed by Exiqon Life Sciences.
- RTM Diagnostika — Diagnostic microwave radio RTM-01-RESThe temperature and rate of growth of malignant tumorsCancer is the terrible disease of breast. That is why the full range of diagnostic measures in mammalogy aimed primarily at identifying it. It is known that the malignant tumor has a higher temperature compared with surrounding tissues. These data werefirst obtained Guture M. French scientist, who, after more than 550 invasive measurements demonstrated that malignancy is determined by its temperature is doubling time. Therefore, the most dangerous, rapidly growing tumors have a very high temperature. It is also known that thermal changes, usually preceded by structural changes. In particular, the thermal changes of the mammary glands come not a moment when the cancer reaches the required size, but much earlier. Studies have shown that even at the stage preceding the malignant growth, namely, when the cells have the expressed proliferation, accompanied by atypical changes, increases the density of microcapillary network, and as a consequence there is a local increase in temperature. Indisputable is the fact that patients with these changes have a high risk of malignancy. Many authors classify this condition as precancerous.The internal temperature - measure of angiogenesisIn 2003, Japanese scientists have shown that the temperature in the cancerous region determined by the density microcapillary network (microvessel density (MVD) [8]. This is the main parameter that characterizes angiogenesis. The density of the microcapillary network when proliferation atypia several times greater than the rate for normal tissues and characterizes the risk of malignancy. in addition, the microcapillary network density refers to the probability of transformation from noninvasive to invasive cancer, the probability of metastasis and tumor growth rate. Therefore, the internal temperature, as a measure of angiogenesis, provides important information about the development of cancer.
- Genizon BioSciences — Since 2005, we have helped thousands of people get the perfect domain name.
Rho Canada Ventures is a division of Rho Capital Partners focusing on early-stage investing in Canada’s most innovative technology companies.The Rho Canada Ventures team comprises a unique combination of entrepreneurial, operational, and venture investment experience in the United States and Canada. With a combined 80 years of experience, RhoCanada Ventures offers entrepreneurs the expertise to turn Canadian innovators into global leaders. Rho Canada Ventures' portfolio companies are a diverse group of investments that span new media, mobile applications, wireless infrastructure, semiconductors and materials, and software.
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Investment focus
- Software, Analytics, Internet
- Series A, Series B, Seed
- Canada, United States, Italy
Portfolio highlights
- Sportlogiq — Sportlogiq is a venture-backed startup that develops sports statistics solutions. Using feeds from current broadcast cameras, the company uses player tracking and activity recognition to analyze player movement and provide context to game analysis. Sportlogiq was founded in 2014 and is headquartered in Montreal, Canada.
- Auvik Networks — Auvik’s cloud-based network management software keeps IT networks around the world running optimally. By automating and simplifying network management, Auvik helps rocket an IT team’s efficiency and capacity, while protecting the business from network risk. Auvik is one of the fastest growing North American technology companies, and is winner ofthe Deloitte Technology Fast 50, Deloitte Fast 500, and recognized as the #1 ranked Canadian company in the FT Americas’ Fastest Growing Companies 2020. Visit www.auvik.com or follow @AuvikNetworks on Twitter. Auvik is a registered trademark of Auvik Networks Inc.
- Resson — Resson Aerospace is a bioinformatics and data analytics company, delivering customized agriculture solutions for large corporate clients. Utilizing recent advances in large-scale cloud-based data processing, swarm robotics, and advanced data analytics, its proprietary Resson Agricultural Management and Analytics System gives the agriculturaloperator analytical insight and dynamic control over the farm area.Resson Aerospace’s Resson Agricultural Management and Analytics System, data-driven agriculture solution, analyzes crop metrics to assess crop status and health, providing operators with the information required to optimize agricultural operations, improve efficiency, boost yields, and maximize profitability. It is headquartered in Fredericton, N.B.
There is more to choosing an investor than selecting the term sheet with the highest valuation. Strategic capital, in its true form, extends the founding team’s capacity. That’s what we do at Rhino. We invest in companies where we can add tangible value. We’ve been on the other side of the table and appreciate the importance of funder and founderalignment. From startup, growth to exit; it is entrepreneurial ambition that drives value, not venture capitalists. We invest in individuals; trust and values fit are a centerpiece in every investment.
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Investment focus
- Financial Services, Software, Education
- Seed, Series A, Funding Round
- Canada, United States, Isle of Man
Portfolio highlights
- MyFO — Leverage AI for effective wealth management with MyFO, making family office services attainable for all.
- Ontopical — Get complete monitoring of emerging local government contracts across North America, months before an RFP is issued. Build your sales pipeline with Ontopical.
- FISPAN — Bridge the gap between your bank and ERP/accounting software. FISPAN partners with your bank to provide embedded, automated solutions for accounts payable and cash management.
National Research Council of Canada Industrial Research Assistance Program
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Investment focus
- Biotechnology, Software, Health Care
- Grant, Seed, Funding Round
- Canada, Norway, Denmark
Portfolio highlights
- Levr.ai — Levr.ai supercharges your team with easy to implement tools that increase conversion, save time and provide a better experience for everyone.
- Dispersa — Harnessing the power of microbe-derived natural solutions to decarbonize the chemicals industry.
- Connektica — Connektica offers telecommunications testing services solutions for RF component measurements in space and terrestrial applications. The company reduces test costs through the use of machine learning and offers decentralized traceability and diagnostic tool.
Northview is a strategic investment and consulting firm focused on the life sciences. Our team combines end-user insight with commercial expertise to develop and advance growth strategies for our clients.
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Investment focus
- Health Care, Biotechnology, Medical
- Series A
- Canada
Portfolio highlights
- Abdera Therapeutics — Custom-engineered radiotherapies to attack cancer in bold new ways
- Precision NanoSystem — Precision Nanosystems develops tools and processes for the development and manufacture of nanoparticles for use as medicines and in medical research. It offers NanoAssemblr benchtop instrument for prototyping of nanoparticles, as well as for the development of nanoparticle-based drugs delivering RNA, small-molecule, and protein therapeutics. Thecompany also provides Neuro9Kit for the study of gene function in neurons and glial cells, as well as potent delivery to primary cells; Test9Kit for the study of gene function in various cell types; and Hepato9Kit for the study of gene function in the liver. In addition, it provides instruments, reagents, and services to the life sciences researchers.
- Perimeter Medical Imaging — Perimeter Medical Imaging is a medical device company driven to transform cancer surgery with advanced OCT technology for surgeons as they strive for clean margins to avoid re-excisions.
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Investment focus
- Software, E-Commerce, Artificial Intelligence
- Seed, Series A, Funding Round
- Canada, United States
Portfolio highlights
- Joyride — Make mobility instantly connected, keyless, shareable and trackable on the world's leading software platform.
- Viggle AI — Viggle AI is a pioneering Canadian firm that uses artificial intelligence to enable people of all skill levels to easily create high-quality animated video using simple text instructions.
- Story Protocol — Powering web3 narrative universes via story legos
Spaceship is a global group of crypto natives, founders, builders, and investors. We aim to invest in, support, and $FUEL blockchain start-ups, emerging crypto networks, and decentralized communities.
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Investment focus
- Blockchain, Credit, Content
- Seed, Series A
- Canada, Portugal, United States
Portfolio highlights
- Octav — Securely interpret DeFi and crypto portfolios with Octav's best-in-class cross-chain monitoring & pre-tax facilitator. Maximize efficiency for finance, accounting, tax professionals. Advanced labeling, reporting & reconciliation of DeFi investments. Latest Web3 dashboard. Elevate Decentralized Finance now.
- Holonym — Holonym Foundation re-architects digital identity with a zero knowledge data custody network. We provide privacy-preserving tools that stop data leaks, key loss, and phishing or hacking attempts.
- VitaDAO — Join VitaDAO, a community owned collective funding early stage longevity research. We fund and commercialize longevity therapeutics.
Accelerate Fund supports the growth of early-stage Alberta technology companies with a multi million dollar fund that combines co-investment from angel investors.
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Investment focus
- Software, Health Care, Information Technology
- Funding Round, Seed, Series A
- Canada, United States
Portfolio highlights
- PulseMedica — PulseMedica is developing a medical device to treat eye diseases that affect over 500 million people worldwide. Our device consists of a state-of-the-art 3D imaging and surgical platform that allows for comprehensive patient treatment.
- Wyvern — Wyvern was created to unlock the secrets of the elec-tromagnetic spectrum by providing groundbreak-ing access to high-resolution and quality imagery.This will enable a sustainable future for humanity.
- Care Group — Care Group is revolutionizing mental health with advanced AI and disruptive technologies, empowering individuals and communities by introducing scalable, user-friendly solutions that respect all users.
Investment focus
- Life Science, Biotechnology
- Pre-Seed
- Canada
Portfolio highlights
- Inspire Biotherapeutics — Inspire Biotherapeutics' objective is to create curative gene therapies for those suffering from lung ailments.
Investment focus
- Life Science, Biotechnology
- Pre-Seed
- Canada
Portfolio highlights
- Inspire Biotherapeutics — Inspire Biotherapeutics' objective is to create curative gene therapies for those suffering from lung ailments.
Ontario Institute For Regenerative Medicine is a biotechnology emergency medicine company.
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Investment focus
- Life Science, Biotechnology
- Pre-Seed
- Canada
Portfolio highlights
- Inspire Biotherapeutics — Inspire Biotherapeutics' objective is to create curative gene therapies for those suffering from lung ailments.
Carnegie Asset Management is a focused and independent asset manager. Their objective is to deliver consistent, long term asset growth for their clients. The combination of a unique investment philosophy based on careful stock-picking and long-term global trends coupled with a stable team of experienced portfolio managers, has over the past 20years resulted in world-class investment results.
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Investment focus
- Biotechnology, Pharmaceutical, Genetics
- Series C, Series B, Funding Round
- Canada, Switzerland, United States
Portfolio highlights
- Agensys — Agensys a biotechnology company, engages in the research and development of therapeutic human monoclonal antibodies and antibody drug conjugates for the treatment of cancer. It offers products to treat various tumors, as well as prostate, pancreatic, and bladder cancers. The company, formerly known as UroGenesys, was founded in 1997 and is based inSanta Monica, California. As of December 18, 2007, Agensys, Inc. operates as a subsidiary of Astellas Pharma US, Inc.
- Genizon BioSciences — Since 2005, we have helped thousands of people get the perfect domain name.
- Santhera Pharmaceuticals — Santhera Pharmaceuticals (SIX: SANN) is a Swiss specialty pharmaceutical company focusing on the development and marketing of innovative pharmaceutical products for the treatment of mitochondrial and neuromuscular diseases. This area of high unmet medical need includes many orphan and niche indications with no current therapy.
Manufacturing & supply chain management: Engineered, specialty & standard fasteners, CNC precision machined components, parts for automotive, aerospace defense, & other industries
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Investment focus
- Software, Aerospace, Architecture
- Seed
- Canada
Portfolio highlights
- Augmenta — Design sustainable, code compliant and fully constructible buildings in hours.
We invest in start-ups that share our drive for purpose.
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Investment focus
- Farming, Agriculture, Life Science
- Seed
- Canada
Portfolio highlights
- Ceragen — Ceragen is a biotechnology company that aims to help farmers increase their crop yields through plant microbiome engineering.It pioneers in the field of precision microbiome engineering through inoculant products that are tailor-made for controlled environment agriculture. The company's products provide farmers with an all-natural solutionto grow more food in less space, reducing the area of land required to feed the human population.It was established in Kitchener, Ontario.
BoxOne Ventures is a privately held investment firm that focuses on early-stage companies across the most impactful, interesting and fast-changing sectors.
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Investment focus
- Biotechnology, Health Care, Software
- Seed, Pre-Seed, Series A
- Canada, United States, Spain
Portfolio highlights
- Talus Bio — Talus Bioscience combines functional proteomics, automated biology, and machine learning to target hard-to-treat transcription factors driving cancer & beyond.
- CytoTronics — Visualize live cell function at scale for cell biology discovery with Pixel systems. Monitor cell viability, morphology, electrophysiology, metabolism and more.
- Axonis Therapeutics — AXONIS Therapeutics, Inc. is advancing breakthrough discoveries to develop first-in-class therapies for neurological disorders.
MVI Finance was added in 2010.
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Investment focus
- Genetics, Life Science, Biotechnology
- Funding Round
- Canada
Portfolio highlights
- Genizon BioSciences — Since 2005, we have helped thousands of people get the perfect domain name.
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