Top 45 eSports Startup Investors in LATAM (September 2026)

Portfolio highlights

• OP_NET — OPNET is a Bitcoin Layer 1 metaprotocol that enables smart contracts to function directly on the Bitcoin blockchain, without the use of sidechains or Layer 2 solutions.
• Watch.fun — Open boxes, collect watches. Pull a Rolex today. Authenticated by Wristcheck. Backed by @SolanaVentures
• Space — Space is a leveraged prediction market platform built on Solana, designed to reward users for accurate insights while enabling efficient capital flow through competitive forecasting, combining high-performance blockchain infrastructure with advanced market mechanisms to create a transparent, scalable, and engaging environment for decentralizedprediction and informed decision-making.

Portfolio highlights

• EBR Systems — EBR aims for outstanding treatment of cardiac rhythm diseases with an innovative leadless therapy.
• Cardiac Dimensions — Cardiac Dimensions, Inc. is a medical device company developing novel interventional tools for the treatment of heart failure and the related condition of mitral valve regurgitation. Our product, the Carillon® Mitral Contour System®, is a groundbreaking, non-surgical device developed to treat functional mitral valve regurgitation. Our system uses acatheter based approach to reshape the mitral valve and reduce mitral regurgitation.
• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• Rivalz Network — Join the connectivity infrastructure between AI Agents, DeFAI and Markets.
• The Arena — A next gen SocialFi app redefining how creators connect, engage, and monetize their content.
• Sigma Computing — Sigma is the only BI analytics tool purpose-built for your cloud data warehouse. Uniquely scalable, with an experience you already know: the spreadsheet.

Portfolio highlights

• Wizzwoods — 1st pixel farm game integrates interchain capabilities with a SocialFi twist.
• SuperIntent — SuperIntent is a cryptocurrency AI app that streamlines on-chain earning tactics. Developed on a multi-agent framework with abundant yield sources.
• SuperGaming — At SuperGaming, we are putting India on the global gaming map.

Portfolio highlights

• SnakeLite — 10-min prediction markets on Hyperliquid whale positions, BTC and ETH. Predict up or down. Settle onchain. From the 100M+ download SnakeLite game.
• Sophon — Soph(+) is a tech studio building novel consumer experiences in crypto and ai. we build, own, and ship our own products, starting with pyre.
• A.A.A C(H+A)RM — AAA C(H+A)RM (Autonomous AI Agents Launchpad & Layer3) is the first AI-first, agent-focused orchestration platform.

Portfolio highlights

• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• Vangrid — Vangrid operates as a decentralized physical infrastructure network.
• Slinky Network — Slinky Network provides an on-chain marketplace and payment protocol that connects AI agents and applications with third-party APIs. The company offers the SlinkyLayer platform, which wraps developer endpoints as discoverable skills and exposes them through an x402 pay-per-execution interface. Each API call triggers a non-custodial on-chainmicropayment, settling in the same request loop using networks such as Base and BNB Chain. Developers set prices, earn a defined revenue share, and receive instant payouts to their wallets without subscriptions or custodial holds. AI agents authenticate via wallet signatures, enabling autonomous, machine-to-machine access and payment without traditional logins or credit cards. The platform also records call ratings on-chain to provide portable, verifiable reputation for services.
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.

Portfolio highlights

• Sharpi — Sharpi offers an AI solution that automates B2B order entry by converting customer messages into structured ERP orders.
• Vixtra — Vixtra is a fintech company that provides payment methods for foreign trade and B2B payment methods.
• Properati — Properati is an online and mobile property platform for the real estate market. The company offers buyers, users, agile, free of ads, banners website, and tenants or real estate investors with a quick, designed for them to be able to communicate effectively with the offeror who has what they are looking for.Properati has an office in Sao Paulo,Brazil, and was founded in 2012 and is headquartered in Buenos Aires, Distrito Federal, Argentina.

Portfolio highlights

• myco — myco is a content streaming super dApp that smoothly integrates AVOD and SVOD capabilities into a decentralized ecosystem.
• Metametaverse — Discover the future of virtual worlds with our metaverse platform. Explore, create and monetize your own metaverse experiences in a seamless and secure manner. Join the cosmic system of metaverses today.
• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• Sumer Money — Sumer Money is a cross-chain synthetic assets protocol that enables composable Defi across blockchains.
• SYNTRA — Live AI trading system. Real-time execution, risk-managed positions, public trade feed. Signals, performance, transparency.

Portfolio highlights

• AEON — Powering #agenticeconomy #x402 | AEON is settlement layer bridging autonomous AI interactions (A2A & A2M) with real-world value flows. Backed by @yzilabs $AEON
• KOR Protocol — KOR Protocol is a decentralized intellectual property (IP) infrastructure designed to empower creators, protect rights, and enable seamless collaboration and monetization of IP assets across various industries, including music, film, TV, gaming, and art. Backed by notable entities like Animoca Brands, Republic, Niantic, Sfermion, Solana, andprominent creators such as Black Mirror, Disclosure, deadmau5, and Richie Hawtin, KOR leverages blockchain, AI, and DeFi to offer a transparent, efficient, and scalable environment for IP expansion.
• Limited — Secure your treasury and scale your business globally with a truly self-custodial account that only you control. No banks. No middlemen.

Portfolio highlights

• Capx — Capx's mission is to accelerate the flow of capital through the private markets, thereby enhancing global capital allocation. With secondary market and enterprise solutions, Capx combines high-quality collections of opportunities with efficient access for institutions and individual investors.
• Noodles Finance — The no-brainer trading platform for Sui.
• YOAKE Entertainment — YOAKE Entertainment is a music studio that specializes in the planning, production, and development of entertainment content.

Portfolio highlights

• 375ai — 375ai is an edge data intelligence network on Solana that provides advanced real-time data collection and analysis to power a smarter, more connected world.
• XTAO — Publicly traded Bittensor company. Bridging TradFi and TAO. (TSXV: XTAO.U | OTC: XTAIF)
• Agentum — Agentum provides an autonomous economic layer built on the BNB Chain that enables AI agents to transact trustlessly with one another without human intervention. The protocol utilizes a combination of TEE confidential computing, zkVM verifiable evaluation, and specialized ERC standards to ensure secure task execution, portable agent reputations, andautomated escrow settlements. By aligning economic incentives at the protocol layer, it ensures that honest machine-to-machine commerce always carries higher payoffs than deceptive practices.

Portfolio highlights

• Seagate Space — Seagate Space is an aerospace company that provides offshore rocket launch solutions for the space industry.
• Applied Atomics — Applied Atomics is a Rapid Response Network in Space.
• ChemT Biotechnology — The goal of ChemT Biotechnology is to increase patient access to the most cutting-edge biologics, beginning with the urgent issues in manufacturing and research and development.

Portfolio highlights

• eMasters — Short term financing makes it possible to acquire highly sought-after domains without the strain of upfront costs. Find your domain name today.
• MarketUP — MarketUP Brasil is an innovative startup that believes in the impact of micro, small and medium-sized enterprises (SMEs) and the entrepreneurial attitude towards the development of the economic scenario, since it is these companies that drive a good part of the country's economy. We believe in these entrepreneurs and offer a complete and freesolution for companies that want to grow and differentiate themselves in the market. We came up with the idea of ​​facilitating the day-to-day business of the SME with a sales and management system capable of managing all the business processes in a simple and uncomplicated way. Our team is composed of experienced people, with relevant history in WEB business development and active participation in the evolution of the Brazilian internet. What was once only available to large companies, now it is within the reach of SMEs without having to pay anything for it. A revolutionary way to run a business. Our system has no use limit and no cost per license, installation, maintenance or paid versions! With tools that encompass purchasing and inventory management, sales, issuance of fiscal documents and financial management. Create your account right now in the MarketUP Management System: https://marketup.com/ Follow MarketUP also: Blog: http://marketup.com/blog Facebook: https://www.facebook.com/MarketUP.Brasil ? fref = ts Instagram: https://www.instagram.com/marketupoficial/?hl=en sales, issue of tax documents and financial management. Create your account right now in the MarketUP Management System: https://marketup.com/ Follow MarketUP also: Blog: http://marketup.com/blog Facebook: https://www.facebook.com/MarketUP.Brasil ? fref = ts Instagram: https://www.instagram.com/marketupoficial/?hl=en sales, issue of tax documents and financial management.
• BovControl — BovControl started providing cloud-based data collection app for cattle management and livestock ranchers. Its apps provides reports, graphics, and analysis of cattle production, through multiple perspectives: processors, brands, ranchers, employees of the farms and technical consultants.Danilo Leao founded BovControl on July 1, 2013. It has itsheadquarters in Silicon Valley and Sao Paulo in Brazil.

Portfolio highlights

• Hitcard — Hitcard is a trendy card culture brand that uses technology to upgrade card-like consumer products.
• Stems Labs — community and platform for collaborative creativity
• MetaverseGo — MetaverseGo is a web 3.0 app that offers easy access to Play-and-Earn Games, Guilds, NFTs, and Decentralized Applications allowing users to own assets, connect with industry players, and use their earnings across multiple payment platforms.

Portfolio highlights

• Humand — Discover our all-in-one HR solution. Experience the best HR software for digital transformation and enjoy the benefits of centralizing internal procedures!
• Pachama — Harnessing AI to drive carbon capture and protect global forests
• NotCo — We are reinventing the foods we love to eat! Same great flavor, but made from plants. Meet the future of food. Why not?

Portfolio highlights

• Loopia — Loopia is an AI-based platform that centralize customer service in e-commerce and marketplaces, transforming support interactions into sales opportunities. With Luna, our intelligent AI agent, businesses can centralize and streamline their customer service, ensuring fast, efficient, and highly scalable support. By automating repetitive tasks andoptimizing response times, Loopia enables e-commerce companies to reduce operational costs while maximizing customer satisfaction and revenue growth.We believe that traditional customer service is outdated, our mission is to elevate it into a strategic sales driver. Every customer interaction should go beyond simple support, it should create meaningful engagement, build brand loyalty, and drive conversions. With Loopia, businesses don’t just solve customer issues, they unlock their full sales potential.
• Pluggy — Pluggy is an Open Finance API platform that connects fintech applications to financial data from users. The company connects applications to their users' financial data, enabling innovators of all sizes and segments to create experiences based on open finance while maintaining complete security and respect for users' privacy.
• UIN — UIN is the BehaviorOS for banks, fintechs, telcos, and retailers. Its AI-powered platform analyzes user behavior and transaction data to orchestrate personalized triggers, incentives, rewards, and experiences that increase activation, frequency, retention, and lifetime value.

Portfolio highlights

• Inkeep — inkeep provides conversational search for developer-focused companies. We use LLMs to understand a company’s docs, GitHub issues, Stack Overflow threads and more to answer developer questions and increase customer activation.
• Material — Unlocking embedded power at any shape
• Arcturus — Experience sports like never before.

Portfolio highlights

• StripChain — StripChain unifies all the blockchains
• Nest Wallet — A Wallet Built for Traders
• Switchboard — Switchboard allows builders to unlock the power of solana by creating high-performance data feeds from any API. They will bring data on-chain that will enable developers to unlock the future of decentralized applications. They enable the SOL community to push any form of data on-chain.

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• SuperIntent — SuperIntent is a cryptocurrency AI app that streamlines on-chain earning tactics. Developed on a multi-agent framework with abundant yield sources.
• Inference Labs — AI hyperscale on decentralized networks - We provide certainty for on-chain AI

Portfolio highlights

• eKyte — eKyte is a complete team work management platform with integrated tools for Projects, Tasks, Processes, Support and Marketing. AI enhances every step, boosting productivity, collaboration and knowledge. It connects all areas and clients, with praised support and unmatched pricing. Achieve Extreme Productivity.
• Pingback Inc — Payment
• BITi9 - Business IT Innovation — BITi9 - Business IT Innovation offers Robbi9, a solution that automates administrative processes focused on increasing productivity and reducing costs. The company is founded with the aim of relating automation technologies and business solutions focused on products with minimum acquisition cost and a lot of agility in implementation.

Portfolio highlights

• DeHR — DeHR develops a talent marketplace with intuitive communication and onboarding tools to effectively connect recruiters and job candidates.
• Step Hero — Step Hero ecosystem combines NFT gaming and deFi. An engaging role-playing game with a fantasy theme, a cross-chained NFT marketplace, NFT collectibles, and the HERO token make up the ecosystem. Additionally, they offer a social network experience with a welcoming neighborhood.
• Himo World — Himo World is a match-3 deck building NFT. It features Free-to-Play, Create-to-Earn & Compete-to-Earn, including Rogue-like PvE & exciting PvP with Tournaments

Portfolio highlights

• VaultN — VaultN's smart distribution platform enables automated self-service distribution of game keys, digital assets, and more. Unlock efficiency, secure revenue, and scale with confidence.
• Rule — Rule is a fintech startup building a ‘save-to-win’ mobile game to combat the ‘ADHD tax’.
• Minit Games — Minit Games provides bite-sized, instantly playable HTML5 games in a tailored, algorithmically driven feed.

Portfolio highlights

• Saf.money — One API to move money across Central America using Bitcoin, stablecoins, and local banking rails.
• Space Ape — Visit Supercell.com and find out more about us and our games.
• Antidote — London-based startup studio for Bitcoin founders

Portfolio highlights

• Nexio — Making Bitcoin Productive
• Turtle Club — Aggregated, diligenced, personalized onchain yield management.
• Neutral Trade — Quant Strategies Marketplace backed by @yzilabs @incubator @ergonia_ | Official Links: https://t.co/LducMMFsw0

Portfolio highlights

• Dual Link — Dual Link has established a strong technological foundation, fuelling our growth and building a reputation as a trusted partner in the hospitality industry. As your technology partner, Dual Link simplifies the complexities of the hospitality industry with integrated solutions that streamline operations and enhance guest experiences. Our suite ofproducts, including our POS, BackOffice HQ, and Payments platform, provides seamless tools designed to empower restaurants and nightlife venues to operate with efficiency and precision. We are committed to equipping our partners with innovative, reliable technology that supports their success and drives their growth.
• Hero Guest — Hero Guest is a digital platform focused on evolving restaurants’ experiences. It improves business profitability through empowered staff, engaged customers, and strategic data. It was founded in 2015 and is based in Lomas de Chapultepec, Mexico.
• PeachWeb — Peach Worlds is the Squarespace for 3D immersive websites. It's the first no-code builder powered by AI, enabling designers to effortlessly create 3D websites without any coding.

Portfolio highlights

• Count — Explore, refactor, and share your data at warp speed.
• Tansley — Tansley is a group of companies (Guaw, Milbby, Brand Story, Bookish) focused on fostering consumer ecosystems around hobbies and passions.
• Passport — Passport is the modern shipping carrier for international ecommerce that helps direct-to-consumer brands ship their products internationally.

Portfolio highlights

• BAYZ — NFT Gaming Startup | Esports & Content Community HUB | #PlayToEarn
• UNXD — UNXD is a curated NFT marketplace for the best of digital luxury and culture. Featuring NFTs from Dolce&Gabbana, Jacob & Co., and more.
• Mon Studios — An indie game development studio

Portfolio highlights

• Play AI — The Orchestration Layer for Crypto x AI
• Metagood — Metagood is the operating layer for tokenized assets across their full lifecycle: compliance, transfer rules, entitlements, corporate actions, and audit.
• VOYA Games — Voya Games is a Berlin-based game development studio. The company focuses on creating a network of interconnected Web3 games centered around player ownership and tokenized economies. Their flagship title, Craft World, is a casual resource management game set in a post-apocalyptic world where players collaborate with friendly dinosaurs to rebuildcivilization. Craft World integrates blockchain features such as NFTs and a utility token called Dyno Coin, enabling players to own, trade, and participate in a decentralized game economy.

Portfolio highlights

• Hemi Labs — Hemi (https://hemi.xyz) is a modular protocol that integrates Bitcoin and Ethereum to amplify and extend the core capabilities of the two leading blockchain networks. This offers a novel perspective on blockchain interoperability and scaling by approaching Bitcoin and Ethereum as components of a single supernetwork. The result providessecurity that exceeds that of Bitcoin (“superfinality”) and new levels of blockchain programmability, portability, and potential. Hemi was co-founded by Jeff Garzik (former Bitcoin core developer) and Max Sanchez (inventor of the Proof-of-Proof consensus protocol), and is surrounded by a team of renowned blockchain engineers, strategic partners and investors.
• Sapien — Sapien offers Data Labelling Services with RLHF to fine-tune your LLMs potential. Improve model performance with better data to improve outcomes. Consult us now!
• Movement Labs — Movement Labs is on a mission to create a global community of Move Builders, working together to improve decentralized network user experience.

Portfolio highlights

• OX.FUN — Trade Bitcoin, Ethereum and trending altcoin derivatives on the most FUN exchange around. Join OX.FUN today and earn up to 200% yield. Moo.
• AINN Layer2 — AINN Layer2 is a decentralized Bitcoin Layer2 network development.It promotes large-scale AI applications
• Sanctum — Stake SOL and earn optimized LST returns from JupSOL, bbSOL, and more, and launch your own custom LST and Solana validator.

Portfolio highlights

• Fjord Foundry — Fjord enables teams the ability to openly and fairly generate liquidity by connecting inspired projects with passionate supporters via Liquidity Bootstrapping Pools.
• Zaros Finance — Zaros is a protocol that provides efficient liquidity, boosts staking rewards from LSTs, and aims to become the preferred liquidity hub for on-chain derivatives.
• Layer Social Labs — A home for global companionship and endless entertainment. Post More, Play More, Earn More.

Portfolio highlights

• Delabs Games — At Delabs Games, we want to create fun games that last a thousand years.
• PublicAI — PublicAI is a Web3 distributed AI training network that helps people to earn rewards by contributing data work.
• Power Protocol — The ecosystem for blockchain entertainment. Fueled by $POWER. Launch Partner: @Fableborne Power Up Your Play

Portfolio highlights

• Shaga — Shaga is a veteran team of blockchain, gaming, distributed systems, and networking professionals.
• Loot Labs — Loot Labs builds ways to acquire digital collectibles.
• Skyfire Systems — Payments and Identity for AI Agents https://t.co/KvM1AGHjTY

Portfolio highlights

• Vestua — Vestua is a secondhand fashion marketplace for women. They sell clothing, sportswear, shoes, wallets, accessories, and brands. Vestua manages the whole process, including receiving garments at home, categorization, online sales, and transferring profits.
• DataRoot — DataRoot provides data science and AI solutions, helping businesses leverage data for growth and optimization.
• BeFun Entertainment — Transformamos marcas globales en experiencias inolvidables.

Portfolio highlights

• Rauda AI — Rauda is an artificial intelligence platform specialized in automating customer service with the best customer experience. Take a quantum leap in productivity, reduce costs and improve customer satisfaction with the power of generative artificial intelligence.
• Aino — AI-powered spatial analytics platform for architecture, urban planning and development teams. Site analysis, GIS-free mapping and location intelligence. 400+ cities covered.
• Orbital Paradigm — Orbital Paradigm builds reusable vehicles that carry cargo to space and bring it back. Dedicated missions, any orbit, on your schedule. Based in Madrid.

Portfolio highlights

• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• Workana — With +10 years in the market, Workana is the largest remote work platform for hiring top talent in Latin America. We match great talent with exciting opportunities and we love doing it. We believe remote work promotes equal and unprecedented growth opportunities for both companies and talent. We are proud to contribute to this new way of workingby connecting freelancers to unique projects and by matching certified developers with long-term roles.More than 600,000 companies find talent on Workana to move their professional projects forward. Meanwhile, we are helping 3 million freelancers develop their professional careers independently.Talent is at the core of what we do. Learn more at www.workana.com
• TinyBytes Games — Best iOS & Android Action Mobile Game Developer and Publisher.
• Wormhole — They are the creators of the first "Live Learning" platform in the market, focused on increasing and improving interaction between people to create the most effective virtual environments for distance learning.They firmly believe that online education is much more that simply looking at static content on a website, that is why theyprovide the best products to manage educational programs, create virtual campuses and improve the teacher-student relation through live online classes, from any computer or mobile device. Their team works with passion, because they love technology and they believe that they can use it to change the world.Nowadays thousands of companies, academic institutions and professional associations in over 10 countries use their platform to improve their education and training programs, saving time and money while increasing their reach. They currently have presence in the USA, Argentina, Brazil and Colombia from where they lead their international expansion and work everyday with the mission to revolutionize the way in which people teach, learn and collaborate online.

Portfolio highlights

• Coliseum Arena — Coliseum is a esports service provider that enables players to compete on high level on a fully automated platform, and partners to provide a high-end experience to their clients.

Portfolio highlights

• AyushPay — Building AI driven risk assessment models to provide personalised subscription healthcare plans
• RumiTech — RumiTech is an initiative that transforms street lighting poles into a grid-independent, next-generation energy and communication infrastructure.
• Arcana Bio — ArcanaBio is developing realtime biosurveillance solutions that minimize workplace disruptions and support health & wellness

Portfolio highlights

• ESGPLAY — ESGPLAY is an e-sports platform used to create competitive games, team building, and organization of events. The company develops apps, software, and anything for gaming purposes. It also arranges IT Infrastructures. In 2018, Johan Bejar set-up ESGPLAY in Lima, Lima.

Portfolio highlights

• Akka — Akka is a platform to build and run apps that are elastic, agile, and resilient. Industry titans and disruptors rely on Akka when application responsiveness must be guaranteed. Engineering teams use a simple SDK and powerful libraries to build transactional, durable, and real-time services that distribute logic and data together. Operations arefully automated in serverless and BYOC environments, and a self-hosted option is available.
• Anima App — Anima is the design-aware AI agent that bridges creativity and code. From Figma files, URLs, or prompts, Anima generates real, production-ready apps, for product teams building directly, or coding platforms integrating via API. Powers Bolt.new and Replit.
• Chicago Quantum Exchange — Home | Chicago Quantum Exchange

Portfolio highlights

• 5ire — 5ire is a blockchain network that brings sustainability, technology, and Innovation to build the 5th industrial revolution (5IR). The mission of the 5ire ecosystem is to embed the for-benefit paradigm at the heart of the blockchain, highly incentivize practices that align with the United Nations Sustainable Development Goals (SDGs), facilitate thetransition from the 4IR to 5IR and accelerate the implementation of the UN 2030 Agenda for Sustainable Development. The company's primary offering is 5ireChain, a layer one, sustainability-driven 5th generation blockchain that ensures adherence to the philosophy of 5IR, creating a net positive impact on the planet and serving humanity.
• Polygen — Polygen provides a breath of fresh air in the world of blockchain launchpads. Current solutions all foster innovation on a specific blockchain, but they also look and operate the same. Fueling innovation in this industry requires the removal of all intermediaries and gatekeepers. Additionally, there is a need for more transparency, automatedprocesses, and post-launch support.
• Ignite Tournaments — Empower content creators to launch custom quest lines, track fan engagement, and manage premium subscription communities.

Portfolio highlights

• Pixelverse — We build Telegram games with memecoins communities. Play here: https://t.co/NH6j76YaZy Powered by $PIXFI
• Mavryk Dynamics — Real assets, Real people, Real solutions. Building a smarter, more secure future. Blockchain, Done Better. Building @MavrykNetwork & @MavenFinanceDAO.
• Swarm Network — Agentic infra for the future $TRUTH NEW: Build your Future agent teams in beta