Top 25 Biotechnology VC Funds in Turkey
A list of 25 VC funds that invest in Biotechnology startups based in Turkey. We rank investors based on the number of investments they made in Biotechnology companies from Turkey. We update this investor list every month.Top 25 Biotechnology VC Funds in Turkey
Investor | Biotechnology Turkey investments |
---|---|
TRANGELS | 6 |
Diffusion Capital Partners | 4 |
ACT Venture Partners | 3 |
Eczacıbasi Momentum | 2 |
APY Ventures | 2 |
Istcapital | 2 |
Sente Ventures | 1 |
SOSV | 1 |
Papara | 1 |
İTÜNOVA | 1 |
ITUARI Teknokent | 1 |
HMG Invest | 1 |
Techmine | 1 |
Genesis Consortium | 1 |
Teknoloji Yatirim | 1 |
Technology & Innovation Fund | 1 |
Alesta Yatırım | 1 |
Founder One | 1 |
Omurga Capital | 1 |
Maxis | 1 |
HATCHER+ | 1 |
PCP | 1 |
Fark Labs | 1 |
Boğaziçi Ventures | 1 |
Gen Pharmaceuticals | 1 |
Early Stage Investment Fund and Network
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Investment focus
- Biotechnology, Energy, Manufacturing
- Seed, Pre-Seed, Angel
- Turkey, United States, Estonia
Portfolio highlights
- & New Me — Explore the best aesthetic treatments in Turkey with New Me. Book a consultation, read reviews, and find the right doctor for your beauty journey.
- Winfluencer — Winfluencer is a platform for automated digital influencer marketing. Their solutions are machine learning, augmented reality, image processing, data analytics, social media analytics, and fraud detection. Winfluencer connects thousands of e-commerce sites through a single platform and an automated system. Because of the new generation affiliatemarketing approach, this system enables users to generate long-term income. Its transparent structure allows both users and the e-commerce site to track sales generated by their interactions.
- Nanomik Biotechnology — Biochemistry leading change in life sciences. With our proprietary technologies, we develop solutions for Crop Health, Animal Health and Food preservation.
Diffusion Capital Partners (DCP) is Turkey's leading Venture Capital fund manager with a focus on deep-tech opportunities.
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Investment focus
- Software, Information Technology, SaaS
- Seed, Series A, Funding Round
- Turkey, United States, United Kingdom
Portfolio highlights
- Doktar Technologies — We lead digitization and digital transformation in agriculture with digital services, sensors, satellites and other agricultural technologies.
- Enhencer — Reach AI based transparent audiences or lookaliles for your ecommerce. Achieve higher campaign conversion and ROAS than ever before.
- Mixer Games — Pioneers who shape the entertainment of the future
Early stage deep tech investor
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Investment focus
- Artificial Intelligence, Software, Manufacturing
- Seed, Convertible Note, Series A
- Turkey, United States, United Kingdom
Portfolio highlights
- Rototip — On demand CNC manufacturing Rototip Milling Turning Bespoke Manufacturing
- Ai Build — Ai Build is a London based company developing Artificial Intelligence and Robotic technologies for large scale additive manufacturing. We believe additive manufacturing is the core technology for achieving a sustainable environment and a highly efficient on-demand economy.We are a team of creative and enthusiastic people with strong background inthe areas of 3D printing, robotics, computer vision, machine learning, computational design and physics. We are partnering with some of the world’s most innovative companies and investors to bring our disruptive Autonomous Large Scale 3D Printing technology into a wide range of industrial applications. Our purpose is to empower factories of the future to make Manufacturing easy, smart, sustainable and affordable.
- Meddenovo Drug Design — Meddenovo is at the forefront of AI-driven drug discovery, pioneering a specialized technology platform designed specifically for cyclic peptides. Our innovative approach leverages a unique blend of AI technologies and molecular modeling to significantly enhance the efficiency and success rates of drug development processes. Cyclic peptidesrepresent a groundbreaking class of compounds in pharmaceutical research. These molecules combine the best attributes of small molecules and large biologics, offering exceptional binding affinities, stability, and specificity. At Meddenovo, we are leaders in harnessing the potential of cyclic peptides, developing tailored solutions that push the boundaries of traditional drug discovery. Beyond small organic molecules, our expertise extends to peptide-based medicines and metal chelators, giving us a competitive edge in novel drug research and development. We excel in creating unique chemical spaces tailored to your needs and provide custom computational solutions for predicting drug resistance, elucidating biochemical reaction mechanisms, and conducting metal affinity analysis. At Meddenovo, we are dedicated to precision and reliability in drug discovery. Our approach reduces failure rates and improves outcomes, accelerating the journey from research to market. Our mission is to empower scientists worldwide with advanced, user-friendly AI tools, democratizing access to cutting-edge drug discovery technologies.
Eczacıbaşı Momentum invested in three venture companies and a venture capital fund; Their goal is to invest US$30 million over the next five years as they continue to partner with funds
and startups that shape the new normal of modern life, focusing on well-being, consumption, and home-living.
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Investment focus
- Medical Device, Information Technology, Neuroscience
- Seed, Series A, Funding Round
- Turkey, United States
Portfolio highlights
- Newlab — Systems for scale
- Ecomercek — Ninico is a modern and flexible Minimal eCommerce Laravel script. This script is suited for electronic, organic and grocery store, furniture store, clothing store, hitech store and accessories store...
- RS Research — RS Research is a next generation therapeutics company developing novel nanomedicines. We have developed a pioneering class of nanocarriers with which we currently have proprietary programs in various stages of preclinical development for treatment of cancer.Our nanocarrier platform is highly tunable with a plug & play approach, allowingspeedy development of targeted nanomedicines with superior performance.Along with moving our very own candidates toward clinic, we provide preclinical services to industrial and academic partners. We have specific expertise in biosimilar characterization as well as in vivo experiment design.
APY Ventures is a venture capital firm focused on early-stage technology startups.
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Investment focus
- Software, Artificial Intelligence, FinTech
- Seed, Funding Round, Pre-Seed
- Turkey, United States, United Kingdom
Portfolio highlights
- Rototip — On demand CNC manufacturing Rototip Milling Turning Bespoke Manufacturing
- Samplico — We deliver products of world-known brands to you for free!
- Cellestetix — Cellestetix is a biotech company that specializes in developing and commercializing plant-based exosome formulas for regenerating skin, hair, and wellness.
ISTcapital is a venture firm where innovation meets investment. Discover our unique approach to venture capital.
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Investment focus
- Biopharma, Video Games, Casual Games
- Seed, Funding Round
- Turkey
Portfolio highlights
- Cellestetix — Cellestetix is a biotech company that specializes in developing and commercializing plant-based exosome formulas for regenerating skin, hair, and wellness.
- Gleam Games — Unique and exciting gaming experiences to enhance gamers' lives. We believe gaming is all about creating a world of unmatched collaboration, immersion, and emotion. At the heart of every gaming experience we create, we aim to bring you the best in-game experiences through design and technology.
- PhiTech Bioinformatics — PhiTech Bioinformatics translates genome-wide molecular data (Genomics, Transcriptomics, Epigenomics, Microbiomics, etc.) into biotechnology solutions primarily for use in precision medicine.
Sente is a Chicago-based startup investment and innovation platform. Sente searches the world for the most high-potential startups and helps them scale through unprecedented guidance, support, and connections.
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Investment focus
- Artificial Intelligence, Machine Learning, Software
- Pre-Seed, Seed, Series B
- United States, Israel, Turkey
Portfolio highlights
- KFOBIX — KFOBIX offers nano-composite materials to prevent freezing and contamination of solar panels, wind turbines, and automobile glass.
- DRONEQUBE — DRONEQUBE provides an innovative SaaS solution that empowers drones to monitor and defend vineyard health autonomously, addressing pressing concerns brought about by the climate crisis and increasing labor challenges.
- Kybele's Garden — Algae Biotechnology for Agrifood & Cosmetics Solutions
SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates.
HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.
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Investment focus
- Biotechnology, Health Care, Software
- Seed, Convertible Note, Pre-Seed
- United States, India, United Kingdom
Portfolio highlights
- MixRift — MIXRIFT - game developers specialized in Mixed Reality
- unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
- Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.
Papara provides simple, fair, and supersonic banking services without boundaries that a bank would have. Shortly, it is the future of banking. With over 7.5 Million Users, Papara is the most trusted and loved finance app both on AppStore and Google Playstore with a rating of 4.9
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Investment focus
- Internet, Security, Software
- Seed, Corporate Round
- Turkey
Portfolio highlights
İTÜNOVA Technology Transfer Office (TTO) offers academic studies and new technologies developed in Istanbul Technical University (ITU) to the benefit of the industry to meet their and help with the development of Turkey by adding value.
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Investment focus
- Biotechnology, Medical Device
- Seed
- Turkey
Portfolio highlights
- MD Research & Development — MD Research & Development are into research and development of innovative products and methods needed in the field of radiation oncology.
ITU ARI Teknokent initiative is a University-industry collaboration that enabled many technology based entrepreneurial companies to benefit form the academic infrastructure provided by ITU.
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Investment focus
- Biotechnology, AgTech, Software
- Seed, Grant
- Turkey
Portfolio highlights
- Kidolog — Kidolog provides support to parents with video or messaging on issues they may need about pre-pregnancy and post-pregnancy.
- eTasin.com — https://etasin.com
- Kolay Karavan — KolayKaravan arose from an idea that we had long considered and developed step by step. The pandemic-induced need for nature, as well as the ever-increasing quest for alternative holidays in our country, cooked the idea of EasyCaravan and unveiled it as a product. It has made it both easy and safe by combining the caravan vacation concept, whichbrings together solutions to housing and transport needs, with the KolayKaravan CamperTrust program. It made it possible for individuals to have this experience... While doing all of this, the Kolay Caravan team keeps "Human" and "Nature" in mind. We consider how we may contribute more to these two areas in all of our work and every decision we make.
Beteiligungsverwaltung. Tätigkeit laut Firmenbucheintrag: Investitionen (Immobilienkauf, Bauherrenmodelle und Unternehmensbeteiligungen)
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Investment focus
- SaaS, Software, Sales
- Seed, Pre-Seed
- Turkey, Austria, Finland
Portfolio highlights
- Caidio — Caidio is here to maximize the quality and productivity of global concrete construction by top notch AI technologies We help our customers increase quality, decrease construction time, and cut cost.
- presono — presono completely rethinks the topic of presenting and combines professional presentations and perfect management in a revolutionary software! Previously unsolved challenges such as outdated slide duplicates, wrong content and designs, rigid presentation flows and complicated updates are a thing of the past with this comprehensive solution!Theintuitive tool ensures that users can create outstanding presentations easily and without extensive know-how, adapt them flexibly and spontaneously even during a presentation. The central data management guarantees that all users are always up to date with the latest information. In addition, it ensures that presentations can be automatically and comprehensively evaluated. Future-oriented features such as multimedia animations and interactive overlays also generate a new factor for attention from which everyone can benefit: the speakers as well as the listeners. After all the tension factor of the presentation is usually directly proportional to the information intake of the audience. In addition, a feedback functionality optimises company-internal communication. The possibility of sending presentations directly as a PDF file or as a link via e-mail also simplifies the work process. Furthermore, presono can be used as a smart sales and trade fair app.presono is therefore much more than just a tool for creating ingenious presentations. presono is an intelligent overall solution that optimizes workflows, generates attention and, as a smart guarantee of success, guides its users safely to the goal of their presentations.
- BioShumm — Probiotic soup (Tirshik Soup), a traditional cuisine, is made from the subspecies of the Arum maculatum plant that grows naturally in the Taurus mountains. Fermented Tirshik Soup strengthens the immune system with its powerful antioxidant content proved with scientificresearch. As a delicious, natural, organic food product that strengthens the human immune system and can be preferred as daily meals. Its public name is “Andırın Doctor”. Making the soup is very labor intensive and traditional methods must be followed carefully. It has been consumed as home meal in the Osmaniye region for centuries and has never been industrially produced until now. After the Covid 19 pandemic, Arum maculatum sales exploded in neighborhood markets. The sellers are calling out loudly about the plant “Corona Killer''. Many people are searching the recipe for tirshik soup online. One of the main problems is that Arum maculatum is naturally harmful to health. After fermentation, it miraculously turns into an extraordinarily beneficial food for human health. On September 20, 2021, a regulation was published by the Ministry of Agriculture and Forestry, stating that It is afterall in the positive category in the list of plants that indicates edible and non-edible ones. Thus, The obstacles for commercial activities regarding Arum maculatum have gone away. Trshika project involves the production of probiotic Tirshik soup using modern biotechnological industrial methods. Lyophilized bacteria produced in the biotech lab will be used with industrial biotechnical fermentation methods and liquid ready made soup will be produced.
Techmine is an Investment firm.
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Investment focus
- Baby, Medical, Biotechnology
- Seed
- Turkey
Portfolio highlights
- KuartisMED — KuartisMED is a biomedical company developing innovative products for healthcare and the well-being of newborns and preterms.
Meet the unqiue investing entities that originated at SOSV and remain closely aligned with our fund.
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Investment focus
- Biotechnology, Fashion, Architecture
- Seed
- United States, Brazil, Turkey
Portfolio highlights
- MAA'VA — MAA’VA™ is developing a proprietary sustainable carbon negative construction material, turning plastic and nonplastic waste into eco-material, advancing solutions to climate change crisis, waste crisis, global river sand shortage, water scarcity and rapid urbanization. Our eco-concrete can be used for both conventional and 3D printingconstruction. By optimizing 3D printing technology we can build environmentally friendly low cost housing with eco-concrete in one day for 1/10th of the construction cost and half of the construction waste.
- West~bourne — delicious, nutrient-rich, and planet conscious snacks, spices and mixes, so you can eat well, do better, and gather often.
- Gozen Bioworks — Gozen Bioworks is a bio-tech company that invents and develops next-gen microbe-derived biomaterials.
Teknoloji Yatirim is a early-stage technology venture capital & private equity firm.
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Investment focus
- Health Care, Internet, Software
- Seed, Series A
- Turkey, Germany, United States
Portfolio highlights
- Hipporello — Turn your task management platform, Trello or Notion, into a powerful service desk. Manage customer support and ticketing easily. Try now for free!
- Mindsite — Mindsite provides e-commerce analytics. Easily monitor key metrics from price to visibility in real time. Increase your online sales.
- VRLab Academy — VRLab Academy | Virtual Experiments
Technology & Innovation Fund was added in 2013.
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Investment focus
- Baby, SaaS, Mobile
- Seed, Funding Round
- Turkey
Portfolio highlights
- KuartisMED — KuartisMED is a biomedical company developing innovative products for healthcare and the well-being of newborns and preterms.
- Webee — Discover WeBee's high-tech hospitality solutions, ensure a contactless guest experience, improve TripAdvisor scores and maximize revenue.
Ales Venture Capital Investment Trust Inc. 100% Escort Technology Investment Co., Ltd. was established in late 2012 as a subsidiary of an investment company subject to the Capital Markets Board legislation.Their target audience was primarily started to produce products or services are targeted at companies with existing customers and growth.However, the product or service to switch to the sales and marketing process, although in need of ready finance companies also take interest in Their initiative.
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Investment focus
- Software, Information Technology, E-Commerce
- Seed, Pre-Seed, Funding Round
- Turkey, United States
Portfolio highlights
- OneNewOne — OneNewOne, which operates in the Human Resources vertical, uses artificial intelligence technology to classify and match the CV Pool in minutes and to enable artificial intelligence to do preliminary interviews using its "Smart Pre-Interview" module.
- Tiamo Games — Tiamo Games combines the simulation and hyper-casual gaming genres.
- Handler — Handler is an artificial intelligence (AI) optimization of game creation processes, including idea, programming, and marketing.
Founder One makes investment at the idea and seed stage in initiatives with measurable impact goals.
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Investment focus
- EdTech, Information Technology, Health Care
- Seed, Pre-Seed, Funding Round
- Turkey, United States
Portfolio highlights
- Kavaken — Kavaken offers artificial intelligence-powered solutions to renewable energy asset owners.
- Materix — Materix is a nanotechnology company collaborating with industry and academia to develop commercializable materials. The company uses thin films for surface properties, providing hydrophobic, photocatalytic, protection, and antibacterial functions.
- The Good Wild — The Good Wild produces plant-based products that enhance nutritional value. The brand offers sprouted and fermented legumes, aiming to preserve natural plant protein.
Omurga Gayrimenkul Portföy is a real estate and venture capital investments firm that brings investment opportunities to investors.It introduces a new investment tool allowing investors to enjoy high returns by collectively investing in large-scale real estate properties or portfolios. Omurga Capital establishes and professionally manages realestate investment funds regulated by the Capital Markets Board of Turkey.
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Investment focus
- Biopharma, Biotechnology
- Funding Round
- Turkey
Portfolio highlights
- PhiTech Bioinformatics — PhiTech Bioinformatics translates genome-wide molecular data (Genomics, Transcriptomics, Epigenomics, Microbiomics, etc.) into biotechnology solutions primarily for use in precision medicine.
- Digital Transformation Group — DT Cloud platform is a global digital transformation cloud computing company with a local presence. Through cloud computing, Big Data and technologies like AI/ML, IoT, Blockchain we enable digital transformation and help governments, organizations and companies of all sizes and industries to further innovate and grow.DT Cloud platform hasstarted with a dream. With the dream of an eighteen years old computer engineering student, who believed in the power of technology and had the desire to make a difference in this world. It was back in 2006 and ever since the desire has only grown. It has been a long journey with trials and failures, growths and successes. But there has always been a passion and true passion is contagious. It has helped to create a wonderful team with curious minds and passionate hearts, build innovative technologies, and bring value to so many customers.Within ten years DT evolved from being a software development and R&D service provider to a telco responsible for thousands of installations of carrier network infrastructure from 2G through to 5G. But we felt it was not enough. In 2018, we packed our experience and created an enterprise-grade 5G-ready multi-regional cloud computing and digital enabling company.Today, DT develops hyper scalable cloud services and innovative solutions to make digital transformation affordable, rapid and secure. By offering more cost-effective, less risky, and faster ways to move, store, and analyze data, DT Cloud platform transforms, optimizes and modernizes industries and people’s lives as a technological enabler both for the physical and digital worlds.
Private Equity Investment arm of Isbank
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Investment focus
- E-Commerce, Internet, Software
- Seed, Funding Round, Pre-Seed
- Turkey, United Kingdom, Estonia
Portfolio highlights
- F4e — Boost employee performance and business results with continuous feedback, transparency, and commitment to business goals.
- Samplico — We deliver products of world-known brands to you for free!
- Cellestetix — Cellestetix is a biotech company that specializes in developing and commercializing plant-based exosome formulas for regenerating skin, hair, and wellness.
Hatcher+ is a data-driven venture capital firm that uses AI and machine learning-based technologies to identify early-stage opportunities in partnership with leading accelerators and investors, worldwide.
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Investment focus
- Software, E-Commerce, Information Technology
- Seed, Pre-Seed, Convertible Note
- United States, Italy, Australia
Portfolio highlights
- Cropify — Eliminating subjective testing from the classification process using AI and machine learning. Cropify.io
- Kybele's Garden — Algae Biotechnology for Agrifood & Cosmetics Solutions
- Cellivate Technology — Startup, with proprietary platform technologies and products that enable cellular meat companies to accelerate the growth of cells
CP is a leading independent private equity firm focusing on investments in Turkey. We invest across growth equity and growth buyout strategies to support visionary entrepreneurs and management teams in fast-growing, export-oriented and tech-enabled companies.
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Investment focus
- Outsourcing
- Private Equity
- Turkey
Portfolio highlights
- Cellestetix — Cellestetix is a biotech company that specializes in developing and commercializing plant-based exosome formulas for regenerating skin, hair, and wellness.
- Unite Bilgi Teknolojileri — Unite is a Nationwide Technology Services Company specializing on IT outsourcing, IT Infrastructure Management, Back Office Capability Management, Business Process Outsourcing. Our expertise lies in understanding the importance of technology to business, the requirement for return on technology investments and the need for an accountablebusiness partner whose core focus is IT management and ensuring all service levels and quality of those services are met. Currently operation in sectors from telecommunication to pharmaceuticals, from Government to Private we would with a large range of outsourcing requirements.
Fark Labs is a global innovation and transformation hub that aims to build a better future for all. We help entrepreneurs, startups, corporations, and investors transform into more connected, innovative, and future-ready versions of themselves so they have a positive impact on the world. We apply an investment portfolio approach to our innovationstrategy, touching all stages of the startup lifecycle from incubator to investor in Turkey, which is strengthened by our strong global network of regional accelerators and VC partners in our key global geographies. We use this approach for our 4 focus verticals: mobility, life sciences, sustainable lifestyle, and emerging technologies, which we call our curiosity cabinet.We back change-makers who transform industries and create new ones. Our sweet spot is investing early, and we continue to provide support and investment up to Series A. We envision a better future by championing entrepreneurship, innovation, and frontier technologies that transform legacy businesses and build future-proof startups.We also drive innovation and transformation through collaborative intelligence. We build a unique ecosystem that connects difference-makers, leading corporations, venture capital firms, universities, and government agencies across our 4 verticals.
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Investment focus
- SaaS, Manufacturing, Last Mile Transportation
- Seed, Series A, Pre-Seed
- Turkey
Portfolio highlights
- Evreka — Evreka is a leading SaaS company providing the most comprehensive intelligent solutions designed for the entire category of waste management across the globe.
- M-Based — M-based is an initiative aiming to develop eco-friendly alternative material technologies using mycelium, a component of the mushroom. Its R&D efforts focus on developing mycelium-based vegan leather to address environmental concerns and animal ethics violations in the textile industry.
- Ion membranes — Ion membranes is a company that designs and manufactures ion exchange membranes and separators for the green energy industry. Our products are used in batteries, electrolyzers, fuel cells, chlor-alkali facilities, electrodialysis water treatment processes, and other applications that require ionic range separation.
Boğaziçi Ventures has been established in 2015 with the purpose of supporting entrepreneurship to take their global success to a next level. We aim to invest in technology start-ups which have talented teams by providing business models and looking for funds and mentoring support for future exponential growth.BV Growth fund will only focus on thetechnology startups established in Turkey at the growth stage while having the ambition to get into the global market.BV Crypto fund will be closed with a minimum fund size of $50M to invest in cryptocurrency and blockchain projects. People are interested in investing in cryptocurrency, especially new initial coin offerings (ICO), but they don’t know which one is reliable. We have an extremely capable team dedicated to cryptocurrency. Our analysts search hundreds of ICO projects, follow their communication, investigate the commitment of their teams, make interviews and if they have a chance, even visit them at their locations to give a much better decision.
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Investment focus
- Software, Information Technology, Gaming
- Seed, Funding Round, Pre-Seed
- Turkey, United Arab Emirates, Sweden
Portfolio highlights
- F4e — Boost employee performance and business results with continuous feedback, transparency, and commitment to business goals.
- Kavaken — Kavaken offers artificial intelligence-powered solutions to renewable energy asset owners.
- Enhencer — Reach AI based transparent audiences or lookaliles for your ecommerce. Achieve higher campaign conversion and ROAS than ever before.
Gen - Making a difference with our products in Rare Diseases, Neurology, Pediatrics, Hematology, Oncology, Endocrinology, Nephrology.
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Investment focus
- Biotechnology, Pharmaceutical
- Series A
- Turkey
Portfolio highlights
- RS Research — RS Research is a next generation therapeutics company developing novel nanomedicines. We have developed a pioneering class of nanocarriers with which we currently have proprietary programs in various stages of preclinical development for treatment of cancer.Our nanocarrier platform is highly tunable with a plug & play approach, allowingspeedy development of targeted nanomedicines with superior performance.Along with moving our very own candidates toward clinic, we provide preclinical services to industrial and academic partners. We have specific expertise in biosimilar characterization as well as in vivo experiment design.
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