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Top 20 Biotechnology VC (Venture Capital) Funds in Portugal in September 2025

Last updated: Sep 2025 A list of 20 VC (Venture Capital) funds that invest in Biotechnology startups based in Portugal. We rank investors based on the number of investments they made in Biotechnology companies from Portugal. We update this investor list every month.

Top 20 Biotechnology VC (Venture Capital) Funds in Portugal in September 2025

Investor	Biotechnology Portugal investments
Portugal Ventures	10
Caixa Capital	6
Bynd Venture Capital	3
Armilar Venture Partners	3
SOSV	2
Critical Ventures	2
Shilling VC	1
Social Impact Fund	1
Ganexa Capital	1
Nina Capital	1
Green Innovations	1
ChangePartners	1
StartUp Health	1
Bionova Capital	1
Boost VC	1
InterCapital Group	1
Artesian VC	1
Pathena	1
WISENEXT	1
InterCapital	1

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Investor list

Verticals:Enterprise, SaaS, Security, Networks, AI, VR/AR, Marketplace, Blockchain, Internet of Things, New materials, Electronics, Robotics, Cleantech, Agrotech, Seatech, Therapeutics, Digital Health, Diagnostics, Innovative Accommodation, Tourist Entertainment Companies, Tour Operators, Wine, Nautical and Equestrian Tourism, Theme ParksMobile, Robotics Founded in 2012, Portugal Ventures is a venture capital firm based in Porto, Portugal. The firm is a part of the Banco Português de Fomento group. The firm seeks to invest in pre-seed, seed and series A stages

Investment focus

Software, Information Technology, Health Care
Seed, Funding Round, Pre-Seed
Portugal, United States, France

Portfolio highlights

Glartek — Glartek's Augmented and Connected Worker solution enables increasing efficiency, safety, and excellence in all industrial operations.
Winalist — Discover and book curated wine tours, tastings, and exclusive wine and spirits experiences across Europe and the US. Explore top vineyards and enjoy personalized recommendations with Winalist.
Mantis-AI — Mantis.AI is an entertainment tech company that takes raw videos and noisy data and shapes them into a masterpiece of organized video clips, enriched data and content insights.

Caixa Capital is the Private Equity and Venture Capital arm of banking Group Caixa Geral de Depósitos and has a track record spanning over two decades of activity, since the industry was created in Portugal. It is a leading investor in terms of funds under management, portfolio size and diversity.Caixa Capital´s mission is to invest in fundsand companies, led by highly qualified management teams, with high growth and valuation potential, that enable our funds to achieve an attractive risk adjusted return and for society at large to benefit sustainably from our activity.Currently with more than 700 million Euros under management and a portfolio of over 80 investments, Caixa Capital is a reference in this area with special links to the respective European sector associations.

Investment focus

Software, Information Technology, SaaS
Seed, Series A, Funding Round
Portugal, United States, Spain

Portfolio highlights

HiJiffy — Increase direct bookings and upselling with HiJiffy's AI-powered communication solutions for hospitality.
Noxus — At Spot, we're crafting the operating system for tomorrow's workforce, harnessing AI to streamline influencer marketing. Our platform empowers agencies, businesses, and content creators to collaborate effectively and reach audiences with ease.
Infraspeak — Infraspeak is an Intelligent CMMS Software that brings outstanding flexibility, connectivity and intelligence to your operations.

Bynd is a leading Iberian Venture Capital firm

Investment focus

Software, SaaS, Health Care
Seed, Pre-Seed, Series A
Portugal, Spain, United States

Portfolio highlights

Dealcar — DEALCAR is a company that digitalizes the used car market through a SaaS platform, enabling fully digital transactions. This platform creates a network effect benefiting dealers, partners, and customers. • Dealers: Increase revenue by selling extra products and boost sales by reducing turnover time. • Partners: Distribute products at the pointof sale without marketing expenses, lowering operational costs. • Consumers: Purchase a used car easily in just three steps, enjoying a smooth, trusted process similar to renting but with the benefits of owning a car.
nuuEnergy — nuuEnergy is a tech-enabled solution aiming to revolutionize the heat pump installation industry. By leveraging technology and industry expertise, we streamline the purchasing and installation process. Our unique approach, refinanced through innovative strategies, promotes a self-reliant and carbon-neutral lifestyle for all our customers.
Relive — Relive is empowering the next generation of real estate entrepreneurs, with a mobile app that allows them to work for themselves, from anywhere, while saving time and earning commissions faster.

Armilar Venture Partners is Portugal's leading venture capitalist. An independent VC with a 20-year-old history, a high-performance track record and an international footprint, Armilar is a deep-tech investor in ICT, HealthTech and CleanTech.

Investment focus

Software, Information Technology, Manufacturing
Series A, Seed, Funding Round
Portugal, United States, United Kingdom

Portfolio highlights

Cintoo — Cintoo is essential for BIM to bridge the gap between your physical and virtual worlds.
Automaise — Radically improve your customer care operations by focusing where the volume is and helping your agents do a better job.
Sword Health — SWORD Health is a digital musculoskeletal (MSK) therapy provider. The company pairs licensed physical therapists with innovative technology to help people overcome their chronic and post-surgical pain faster and more cost-effectively. We’re on a mission to free two billion people from pain by making it simple for people to recover at home, withoutresorting to imaging, surgeries, or opioids. Since launching in 2015, SWORD Health has worked with insurers, health systems, and employers in Europe, Australia, and the U.S. to give thousands of people access to preventative, chronic, and post-surgical MSK care that gets results. SWORD Health has offices in New York City, Chicago, Salt Lake City, Sydney, and Porto.

SOSV is a global, deep tech venture capital firm that operates the HAX and IndieBio startup development programs focused on human and planetary health. SOSV invests $500,000 in startups at their inception as they onboard either HAX or IndieBio for a 4-6 month period designed to accelerate the raise of their next institutional round. SOSV joins thelater rounds of HAX and IndieBio graduates. HAX, based in a 35,000 sq ft facility in Newark, NJ, is equipped with machine tools, 3D printers, chemical, electrical and mechanical engineering labs, as well as on-staff engineering and design experts. SOSV's IndieBio has locations in NYC and San Francisco, both of which offer extensive services and facilities to founders including on-site BSL-2 labs, well equipped lab benches and hoods, and advanced lab equipment, such as chromatography equipment.

Investment focus

Biotechnology, Health Care, Software
Seed, Convertible Note, Pre-Seed
United States, India, United Kingdom

Portfolio highlights

MixRift — MIXRIFT - game developers specialized in Mixed Reality
unspun — From 3D scan to perfect fitting custom jeans. unspun makes each pair of jeans unique to your actual body and design. On a mission to reduce global carbon emissions by 1%. As seen in Fast Company's World Changing Ideas, Time's Best Inventions, and PopSci's Best of What's New. Welcome to the future of apparel.
Mesa Quantum — Unlock the potential of chip-scale quantum sensing for enhanced Position, Navigation, And Timing capabilities. Explore Mesa Quantum's practical solutions.

We invest in game-changing companies with the power to transform the way the world uses technology.

Investment focus

Medical, Computer, Genetics
Seed, Series A
Portugal, United States

Portfolio highlights

hOS — hOS is an early-stage AI technology company.
CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!
RunSafe Security — Secure embedded systems with RunSafe Security's runtime cybersecurity protection, integrating build-time defenses without affecting performance.

Shilling is an early-stage venture capital firm backing exceptional founders from the start.Shilling invests in a wide range of verticals and seeks out the biggest opportunities across all B2B and consumer categories. Leveraging the concept of Founder LPs, Shilling brings much more than capital and offers through its Shilling Platform, directaccess to successful founders and executives of leading companies. This platform supports entrepreneurs in validating and developing their ventures, which then accelerate their growth into global markets.

Investment focus

Information Technology, Software, Internet
Seed, Pre-Seed, Series A
Portugal, Spain, United States

Portfolio highlights

Cafler — Your car's personal assistant. Ask for a Cafler now, we move your car for you!
Relive — Relive is empowering the next generation of real estate entrepreneurs, with a mobile app that allows them to work for themselves, from anywhere, while saving time and earning commissions faster.
specter automation — Construction is the second least digitized sector in the world with 96% of all data being unused. Although detailed planning data is created upfront, a lack of suitable digital tools prevents its transfer to the construction site. SPECTER’s web-based construction management software uniquely incorporates the core components of constructionplanning, reducing the organizational burden on construction management and helping to meet project timelines and budgets.

Ability to open doors on opportunities (potential clients/strategic partners/suppliers/etc). Add market credibility, something missing in many start-ups.Know-how that can save you time, money and unnecessary stress and worry. Ability to complement the existing management team, filling gapsThey understand the difficulties andhardships of starting and building a business. They are motivated to work with you on the building process, and not just wait for the end result

Investment focus

Health Care, Fitness, Wellness
Seed, Pre-Seed, Funding Round
Portugal, United States, United Kingdom

Portfolio highlights

Abtrace — Abtrace is an automated, self-learning care system where we can provide personalised care, delivered at population scale - where predictive, preventative and proactive approaches keep people healthy and out of hospital.
sheerME — SheerME is Revolutionising the way people find, book, and pay for their Wellness and Beauty services powered by a benefit-based walletOur approach is based on Discovery, Transaction & Reward to create more online visibility, reach, conversion into new business, loyalty, and frequency through our wallet and cashback ecosystem, to all ourpartners in the beauty and wellness sectors.This made us a fresh and different option in this sector where there are mainly SaaS players, and we bring marketplace with no monthly fee, only a commission for business sent through our owned and partner channels.
ChemiTek — Certified & sustainable solutions for industrial maintenance. We have the solutions you need!

We deploy early stage capital to fuel the growth of need-driven health technology companies.

Investment focus

Health Care, Artificial Intelligence, Medical
Seed, Pre-Seed, Series A
United States, United Kingdom, Germany

Portfolio highlights

CryoCloud — CryoCloud Accelerate your protein structure determination - Bring your cryo-EM data analysis to the next level by using our cloud-based image analysis workflow.
EarlySight — EarlySight start-up company is founded in order to accelerate the development and to bring the technology to clinics.
Magentiq Eye Ltd — AI assisted colonoscopy by MAGENTIQ EYE set a new standard of , recognized by the gastroenterology community for its superior performance.

International, Life Sciences, Biotechnology

Investment focus

Medical, Genetics, Health Care
Series A
Portugal

Portfolio highlights

CBR Genomics — We apply our end-to-end solutions to hand genetic reports at the clinical desk. We make Genomics accessible!

ChangePartners is an independent company dedicated to mid-size transactions in the Iberian market. They develop high value added solutions specific to each particular situation , offering a fair and unbiased opinion. Their independence guarantees no conflicts of interest. Their small size and focus ensures full dedication to each transaction.

Investment focus

Medical, Therapeutics, Biotechnology
Seed
Portugal

Portfolio highlights

Exogenus Therapeutics — Exogenus Therapeutics is engineering cell biology for innovative therapeutic solutions.Exo-T is a biotechnology company dedicated to the pre-clinical and clinical development of innovative cellular-based therapies applied to regenerative medicine, specifically for the skin lesions treatment. The company is presently developing its first product,Exo-Wound, for the treatment of chronic wounds.The project that led to the creation of the company (Nanoinspire) participated in COHiTEC 2014 program and is the result of the research developed in collaboration with Crioestaminal SA, Biocant, and Centre for Neurosciences and Cellular Biology of Coimbra University.

Organizing and investing in a global army of entrepreneurs committed to achieving health moonshots

Investment focus

Health Care, Wellness, Medical
Seed, Funding Round, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

AvoMD — AvoMD is reimagining clinical decision support with interactive point-of-care software, available standalone and via EHR integrations, and seamless content building tools.
JETSWEAT — Jetsweat is a well-being platform that helps organizations engage populations to live healthier lives. We partner with forward-thinking employers, health plans and health systems to set a new standard for holistic and preventative care, driving better outcomes through engaging journeys, personalized programming from exclusive provider ecosystem,and dedicated white-label software.
Hidoc Consult — Hidoc Consult: Boost your well-being with free consultations, 24/7 access to quality healthcare, complete privacy, user-friendly, and a trusted network of HCPs

Bionova Capital, previously known as Hovione Capital, is a healthcare-focused venture capital firm, investing in early-stage life science companies. It was founded in 2015 by the shareholders of Hovione, one of the largest pharmaceutical companies in Portugal, with manufacturing and research operations in USA, Ireland, China and Portugal. BionovaCapital invests in groundbreaking therapeutics, medtech and digital health startups across Europe.

Investment focus

Biotechnology, Hospital, Health Care
Seed, Funding Round
Portugal, United Kingdom

Portfolio highlights

Delox — Delox is a spin-off of the Faculty of Sciences of the University of Lisbon (FCUL), whose goals consist in the design, development, and production of a vast portfolio of automatic biodecontamination robots. Target applications include the sterilization of medical devices in hospitals, health centers and field hospitals (for humanitarian missions,catastrophe situations, and war zones); room biodecontamination in hospitals, pharma, food industry and space; and laboratory equipment biodecontamination.
CellmAbs — Pharmaceutical Company, Biotechnology
Adapttech — Adapttech is a biomedical company that uses innovative, smart and wearable technologies to deliver full adaptation and comfort to people with physical limitations.

Boost VC: The Pre-Seed Fund Making Sci-FI a Reality. Investing in crypto, virtual reality, augmented reality, AI, Ocean Tech, Space Tech, human augmentation, exoskeletons and more.

Investment focus

Software, Blockchain, Virtual Reality
Seed, Pre-Seed, Funding Round
United States, Canada, United Kingdom

Portfolio highlights

Neurvona — AI Digital Twin Personas
Castle — Castle is a technology company that makes it easy for companies to add bitcoin to their treasury, regardless of their knowledge of bitcoin. We enable businesses to go from zero to bitcoin in less than 48 hours.
m00m world — m00m multiplayer sci-fi world! Build your container home, make friends, play mini-games, and fight the F8 Corporation. Based on our audio series and webcomic.

InterCapital Group provides management consulting and business advisory services to a wide range of companies, executives management teams and startups. We have the capacity to assist our clients in a variety of ways including business strategy, marketing plans, product development, angel investment or venture capital raises, social mediaconsulting, human resources, operational improvement, developing or strengthening a executive team or advisory board .The InterCapital Group typically works with clients and companies with less than $10 million on annual revenue. Current and past clients consist of companies from many sectors including financial services, consumer web, high-tech, software, mobile, media, communications, retail, hospitality, consumer products, consumer services, social media, nonprofits, insurance and wealth management.

Investment focus

Biofuel, Biotechnology
Seed
Portugal

Portfolio highlights

BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

Artesian Capital Management is an alternative investments management company, which was spun out of ANZ Banking Group's capital markets business in 2004, with backing from ANZ Private Equity. Artesian's founding partners, purchased ANZ's stake in 2005. The company has subsequently been fully owned by partners and staff. Since 2004,Artesian has managed specialised funds focused on credit arbitrage and relative-value strategies across global financial markets. In 2008, while continuing to manage credit relative value investment strategies from its New York, London and Singapore offices, Artesian began to make principal investments in seed/early-stage ventures from its offices in Sydney, Melbourne and Shanghai. In 2011, Artesian launched the first of its early stage venture capital funds and now manages AUD +255m. Artesian's VC strategy is to partner with best of breed accelerators, incubators, angel groups and university programs. In 2017, Artesian launched its China VC Fund with a USD 50m cornerstone investment industry super fund Hostplus. Artesian will soon launch a Southeast Asia VC Fund.

Investment focus

Software, Artificial Intelligence, Health Care
Seed, Pre-Seed, Series A
Australia, United States, Hong Kong

Portfolio highlights

Voltavate — Voltavate is dedicated to driving innovation in battery technology to support the global transition towards sustainable energy solutions.
Strong Room AI — Software that enables high-strength care through streamlined workflows, continuous analytics, surfaced insights and safeguarded data.
SAMA Fertility — SAMA Fertility is a virtual fertility clinic that offers fertility care and treatments, including preservation and evaluation services.

Pathena is an investment firm engaged on boosting the success of information technology and digital biomedical companies.

Investment focus

B2B, Made to Order, Marketing
Series A, Seed, Series C
Portugal, Germany

Portfolio highlights

BIZAY / 360imprimir — • Bizay has empowered more than 1 Million SMB’s to grow their businesses during the last 5 years.• Bizay is a tech-based B2B Marketplace for made-to-order products. Running a fabless business model (no capex), it leverages on the idle capacity of production partners to meet the needs of the SMB’s.• Started on printing, packaging, textile andprofessional products and now applying the same model in furniture, food and 3D printing (amongst others).• 360imprimir / 360onlineprint - rebranded to Bizay - Your bussiness your way - to reflect the unlimited product categories. • Bizay is the customer facing brand (the SMB’s do not meet the production partners) and its tech platform manages the production by: o Using data and algorithms to aggregate different orders and to decide in which suppliers to produce them, driving huge efficiency and speed gains. o Enabling full tracking of the orders in the different production partners and automating pre-production processes.• Bizay differentiates themselves from other players by offering: o Online configuration of the products (options to customize and personalize). o Competitive pricing for small and medium orders (similar price per unit as for large orders), 48 hours of delivery time (instead of several weeks) and guaranteed quality (customer-facing brand ensuring high quality levels). o Integrated value chain in a single offer (on-demand design services provided by external providers).• Originally selling in Portugal, Spain, Brazil and México, the company raised B round of 18m€ one year ago (communicated in April) in order to launch new countries.• 17 new countries were launched in 2019 simultaneously (including DE, FR, UK and USA).• In 2019, 8 months of trading in the new countries confirm: o Competitiveness pricing of their offer in all the market. o Market deepness and sound acquisition metrics.
Promptly — Health Analytics Patient Report Outcomes, Health Care, Value based health
NVision Imaging Technologies — NVision Imaging Technologies is leveraging advances in quantum physics to enable the first routine, convenient and affordable use of Magnetic Resonance Imaging (MRI) for assessing early patient response to cancer treatment at the metabolic level.

WiseNext is a venture and smart capital investment company. We focus on helping young entrepreneurs with innovative ideas that have an impact on our society, providing capital, knowledge and networking.

Investment focus

Software, Artificial Intelligence, Internet
Seed, Pre-Seed
Portugal, United States

Portfolio highlights

pleez — Pleez offers Restaurant's an optimisation of their menu within Delivery Platforms, so that they can have a revenue increase up to 25%.
Volup — Volup is a premium food delivery app that partners exclusively with top-tier chefs and restaurants.
Relive — Relive is empowering the next generation of real estate entrepreneurs, with a mobile app that allows them to work for themselves, from anywhere, while saving time and earning commissions faster.

InterCapital is an investment firm focused on early-stage ventures. InterCapital cooperates with outstanding Entrepreneurs, promoting innovative ideas and business models, leading to positive social and environmental impact.

Investment focus

SaaS, Human Resources, Biofuel
Funding Round, Seed
United Kingdom, Portugal

Portfolio highlights

Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
Benivo — Increase satisfaction for employees and HR by >50% NPS. Save 30-70% on costs.
BioMimetx — BioMimetx is a biotech startup focused on the development of green antifouling solutions to prevent marine biofouling. The company discovers and owns environmental bacteria that secrete molecules, which are used as natural antimicrobials and algaecides. BioMimetx is based in Cantanhede, Portugal.

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