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Top 25 Biotech Angel Investors in Spain in February 2025

Last updated: Feb 2025 A list of 25 angel investors that invest in Biotech startups based in Spain. We rank investors based on the number of investments they made in Biotech companies from Spain. We update this investor list every month.

Top 25 Biotech Angel Investors in Spain in February 2025

Investor	Biotech Spain investments
Gus Bertolo	2
Fabio Núñez	2
Juan Knuth	2
Alberto Hospital Marco	2
Ritu Bansal-Mutalik	1
Alfons Hidalgo	1
Arnaldo Marziali	1
Torres Quevedo	1
Juanjo Mostazo	1
Montserrat Esteve	1
Milad Alucozai	1
Ryan Bethencourt	1
Mario Pablo Sánchez Barrón	1
Pedro Lizondo Siguero	1
Inaki Berenguer	1
Mercedes Gonzalez Gorbena	1
Fernando García Abasolo	1
Arman Anatürk	1
Mariliis Holm	1
John Bethell	1
Arturo Elizondo	1
Others Others	1
Javier Alsina	1
José Bendayan	1
David Brandes	1

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Investor list

Gus Bertolo

Investment focus

Software, Biotechnology, Artificial Intelligence
Seed
Spain

Portfolio highlights

Insectius — Insectius uses artificial intelligence (AI) in insect breeding, management, and manufacture of insect flour.

Fabio Núñez is an Angel Investor.

Investment focus

Software, Biotechnology, Artificial Intelligence
Seed
Spain

Portfolio highlights

Insectius — Insectius uses artificial intelligence (AI) in insect breeding, management, and manufacture of insect flour.

Juan Knuth

Investment focus

Health Care, Biotechnology, Digital Media
Seed, Series A
Spain

Portfolio highlights

Devicare — Devicare designs point-of-care medical devices that monitor, diagnose and treat chronic diseases. The company's medical devices are useful in measuring the level of biomarkers in body fluids such as saliva, tears, sweat, sputum, feces, urine or blood, enabling medical professionals to detect and treat various infectious diseases.

Alberto Hospital Marco

Investment focus

SaaS, Software, Logistics
Seed
Spain

Portfolio highlights

Freightol — Freightol is a technological startup with the mission to digitize the transport and logistics industry. To make this industry more innovative and efficient, we used Freightol Manager, a complete digital platform that digitizes all parts of a Global Freight Forwarder: its logistical operations, handling and management of shipments, quotations,billing and customs, from the beginning to the end in real time.
Insectius — Insectius uses artificial intelligence (AI) in insect breeding, management, and manufacture of insect flour.

Ritu Bansal-Mutalik is a Senior Director, Process Research and Development at ZymoChem.

Investment focus

Wellness, Life Science, Biotechnology
Seed
Spain

Portfolio highlights

Libre Foods — MEAT, BUT MAKE IT MUSHROOMS. GET READY TO TASTE THE POWER OF FUNGI

Alfons Hidalgo

Investment focus

Medical, Biopharma, Life Science
Funding Round
Spain

Portfolio highlights

Affirma Biotech — Affirma Biotech develops new orally available immunotherapeutic drugs for the treatment of severe infections and cancer

Arnaldo Marziali

Investment focus

Big Data, Software, Life Science
Pre-Seed
Spain

Portfolio highlights

Seqera — A seamless experience for data pipelines at scale with Nextflow. Deploy workflows, complex pipelines, and data-intensive applications in the cloud.

Torres Quevedo

Investment focus

Biopharma, Therapeutics, Biotechnology
Seed
Spain

Portfolio highlights

Oniria Therapeutics — Modulating cell dormancy to overcome cancer persistence

Juanjo Mostazo

Investment focus

Artificial Intelligence, B2B, Mobile Apps
Seed, Pre-Seed, Angel
Spain, Colombia

Portfolio highlights

Nuela — Nuela utilizes AI to automate the creation of schedules and management of substitutions in educational centers.
Rauda AI — Rauda is an artificial intelligence platform specialized in automating customer service with the best customer experience. Take a quantum leap in productivity, reduce costs and improve customer satisfaction with the power of generative artificial intelligence.
Mas Leads — Mas Leads Technologies, through its SaaS (Software as a Service), assists B2B firms' Marketing and Sales Departments in obtaining the best real-time data on new potential clients in national and international marketplaces, thereby automating the lead creation process.

Montserrat Esteve

Investment focus

Health Care, Neuroscience, Biotechnology
Seed
Spain

Portfolio highlights

FreeOx Biotech — Based on the knowledge of oxidative stress and uric acid, Freeox Biotech is developing neuroprotective therapies to reduce the damage resulting from ischemia and in this way improve the recovery of the patients. Ox-01 is Uric Acid used as a medicinal product. Ox-01 has a proven effect in preventing the damage caused by reperfusion after stroke.Ox-02 Uricoline is a molecule resulting from the association of Ox-01 and Citicoline. Citicoline is an intermediate in the generation of phosphatidylcholine from choline.

Dr. Milad Alucozai is an Afghan-American neuroscientist, entrepreneur, biotech executive, and global investor with nearly two decades of experience in deep tech, primarily in life sciences. He pushes the boundaries of bioengineering and computational advancements, integrating machine learning and artificial intelligence into biology and medicine.With a strong commitment to commercializing transformative technologies and fostering startup ecosystems worldwide, he is a thought leader and formal mentor for entrepreneurs through organizations like Creative Destruction Lab and the Wyss Institute at Harvard Medical School.Currently, Milad is the head of Bio and Deep Tech at BoxOne Ventures, where he spearheads the firm’s investments in early-stage companies with breakthrough scientific ideas. With nearly 80 early-stage investments, they are recognized as one of North America’s most active venture firms. He is also a Venture Partner at Entrepreneur First, a global fund that has built over 500 companies from scratch with an enterprise value of $10bn. He supports founders with strategy, scaling, business development, securing growth capital, and leadership training, often being their first investor and guiding them from startup inception to IPOs or acquisitions.He started his career in translational neuroscience and multiphysics laboratories before transitioning into founding roles at biotech startups. He is part of the founding team at Mekonos, a San Francisco-based company creating a proprietary cell-engineering platform to support the future of cell and gene therapies. He was also part of the founding team at Corstem, which specialized in machine learning and artificial intelligence software and was later acquired by Circle Cardiovascular, a platform in over 1000 hospitals and more than 40 countries. At Accenture, Milad directed teams of data scientists, designers, and engineers in developing artificial intelligence platforms for global pharmaceutical companies and hospital networks.Milad serves as a Fellow in Healthcare Engineering at the Regenstrief Center. In 2020, he served as an External Advisor to AstraZeneca. He was recognized as a National Science Foundation Scholar and Macklin Fellow at Johns Hopkins Medicine. He graduated Phi Beta Kappa with a degree in Neuroscience from Purdue University’s Honors Program. As a George J. Mitchell Scholar, he completed his master’s in Immunology and earned his doctorate from the Richard M. Fairbanks School of Public Health.

Investment focus

Biotechnology, Health Care, Medical
Seed, Series A, Pre-Seed
United States, Canada, United Kingdom

Portfolio highlights

Arpeggio Bio — We engineer medicine based not on a single target, but the biological network as a whole.
Future Fields — Future Fields Cellular Agriculture: Serum-Free Growth Media Supplements and Recombinant Proteins - Optimized for the Future of Food.
Eigen Therapeutics — Eigen Therapeutics is a biotechnology company developing combination therapeutics for cancer. The company is in the research and development of synergistic therapies that improve efficacy while reducing the toxicity of small molecule therapies and immunotherapies, enabling physicians to get access to novel drugs in areas of unmet medical needs.

Ryan is a co-founder and CEO at Wild Earth and a co-founder and Partner at Sustainable Food Ventures, bringing years of experience in leading, building and advising high-growth food and biotechnology companies. Ryan is a biotech entrepreneur, investor, and one of the founders of the biohacker movement. He’s a co-founder and former Program Directorat IndieBio and has invested in over 130 early stage biotech startups and served as the head of life sciences at the XPRIZE Foundation. As an ethical vegan, Ryan is passionate about the future of biology as a technology, applied across all industries to solve some of humanity’s most intractable problems. Ryan fosters dogs for Rocket Dog Rescue and is passionate about mindfulness, meditation, and mentoring. His work at the interface of science, food, and business has been covered by many major publications.

Investment focus

Biotechnology, Food Processing, Food and Beverage
Pre-Seed, Seed, Angel
United States, Chile, India

Portfolio highlights

WTH Foods — WTH Foods is a plant-based alternative protein company based in Manila, Philippines. Using local and sustainable ingredients, we create plant-based versions of processed meat products that Southeast Asian love
Sobo Foods — Sobo Foods is a plant based comfort food provider.
Libre Foods — MEAT, BUT MAKE IT MUSHROOMS. GET READY TO TASTE THE POWER OF FUNGI

Mario Pablo Sánchez Barrón , CEO of Startidea.

Investment focus

EdTech, Children, Education
Pre-Seed
Spain

Portfolio highlights

Neuromindset — In an ever-evolving digital era, the mental abilities and emotional health of children often get overshadowed. Envision a world where the essence of education transcends mere knowledge, nurturing every child to unlock their cognitive and emotional prowess using evidence-based tools. At Neuromindset, a Spin-off of the University of Granada (Spain),this isn't just a dream—it's our mission. Our purpose? Seamlessly integrate cognitive and brain training into the very fabric of schooling and home environments. Our dual B2B and B2C models cater to educators and families alike, fortified by three pioneering instruments. Firstly, a classroom-integrated platform that provides educators with a training curriculum that includes mindfulness and game-based activities grounded in rigorous neuroscientific research, empowering students to enhance their attention, executive functions and self-regulation. Secondly, an interactive at-home gaming app, meticulously crafted to cultivate cognitive prowess, making the training both captivating and consequential. And lastly, our avant-garde AI assessment of attentional profiles, not just delineating a child's cognitive map but also tailoring their training, fortifying frailties, and magnifying mights. Neuromindset's hallmark is our dedication to fortify children's mental well-being, bolstering self-regulation, and providing AI-infused, personalized cognitive training. With Neuromindset, education it's not just about learning—it's about flourishing in every sense.

Pedro Lizondo seguiro is an individual investor.

Investment focus

EdTech, Children, Education
Pre-Seed
Spain

Portfolio highlights

Neuromindset — In an ever-evolving digital era, the mental abilities and emotional health of children often get overshadowed. Envision a world where the essence of education transcends mere knowledge, nurturing every child to unlock their cognitive and emotional prowess using evidence-based tools. At Neuromindset, a Spin-off of the University of Granada (Spain),this isn't just a dream—it's our mission. Our purpose? Seamlessly integrate cognitive and brain training into the very fabric of schooling and home environments. Our dual B2B and B2C models cater to educators and families alike, fortified by three pioneering instruments. Firstly, a classroom-integrated platform that provides educators with a training curriculum that includes mindfulness and game-based activities grounded in rigorous neuroscientific research, empowering students to enhance their attention, executive functions and self-regulation. Secondly, an interactive at-home gaming app, meticulously crafted to cultivate cognitive prowess, making the training both captivating and consequential. And lastly, our avant-garde AI assessment of attentional profiles, not just delineating a child's cognitive map but also tailoring their training, fortifying frailties, and magnifying mights. Neuromindset's hallmark is our dedication to fortify children's mental well-being, bolstering self-regulation, and providing AI-infused, personalized cognitive training. With Neuromindset, education it's not just about learning—it's about flourishing in every sense.

Inaki Berenguer is the President and Co-founder at iPronics Programmable Photonics.

Investment focus

E-Commerce, FinTech, Software
Seed, Angel, Pre-Seed
Spain, United States, United Kingdom

Portfolio highlights

Bankflip — Permissioned data technology to collect and process your customers' income, tax, employment & other relevant data & documents in real-time
Libera Bio — Libera Bio is a biopharmaceutical company devoted to the development of a new class of therapeutics to address unmet medical needs in cancer
Mable (Neurolytic Healthcare) — Neurolytic Healthcare provides personalized medicine for neurological conditions. Neurolytic Healthcare collects and extracts insights from a combination of genetic and biomarker data to enhance diagnosis and help clinicians decide on optimal treatment strategies for neurological conditions.The company delivers digitally and genomically-drivenmedical devices to improve the current treatment of migraine and other neurological disorders, including a diagnostic support tool, pharmacogenetic test, and a mobile app for migraine event prediction.

Mercedes Gonzalez-Gorbena is the Chief Product Officer at TES Global.

Investment focus

EdTech, Children, Education
Pre-Seed
Spain

Portfolio highlights

Neuromindset — In an ever-evolving digital era, the mental abilities and emotional health of children often get overshadowed. Envision a world where the essence of education transcends mere knowledge, nurturing every child to unlock their cognitive and emotional prowess using evidence-based tools. At Neuromindset, a Spin-off of the University of Granada (Spain),this isn't just a dream—it's our mission. Our purpose? Seamlessly integrate cognitive and brain training into the very fabric of schooling and home environments. Our dual B2B and B2C models cater to educators and families alike, fortified by three pioneering instruments. Firstly, a classroom-integrated platform that provides educators with a training curriculum that includes mindfulness and game-based activities grounded in rigorous neuroscientific research, empowering students to enhance their attention, executive functions and self-regulation. Secondly, an interactive at-home gaming app, meticulously crafted to cultivate cognitive prowess, making the training both captivating and consequential. And lastly, our avant-garde AI assessment of attentional profiles, not just delineating a child's cognitive map but also tailoring their training, fortifying frailties, and magnifying mights. Neuromindset's hallmark is our dedication to fortify children's mental well-being, bolstering self-regulation, and providing AI-infused, personalized cognitive training. With Neuromindset, education it's not just about learning—it's about flourishing in every sense.

Fernando García Abásolo is a businessman passionate about neuroscience and innovation to improve the potential of children.

Investment focus

EdTech, Children, Education
Pre-Seed
Spain

Portfolio highlights

Neuromindset — In an ever-evolving digital era, the mental abilities and emotional health of children often get overshadowed. Envision a world where the essence of education transcends mere knowledge, nurturing every child to unlock their cognitive and emotional prowess using evidence-based tools. At Neuromindset, a Spin-off of the University of Granada (Spain),this isn't just a dream—it's our mission. Our purpose? Seamlessly integrate cognitive and brain training into the very fabric of schooling and home environments. Our dual B2B and B2C models cater to educators and families alike, fortified by three pioneering instruments. Firstly, a classroom-integrated platform that provides educators with a training curriculum that includes mindfulness and game-based activities grounded in rigorous neuroscientific research, empowering students to enhance their attention, executive functions and self-regulation. Secondly, an interactive at-home gaming app, meticulously crafted to cultivate cognitive prowess, making the training both captivating and consequential. And lastly, our avant-garde AI assessment of attentional profiles, not just delineating a child's cognitive map but also tailoring their training, fortifying frailties, and magnifying mights. Neuromindset's hallmark is our dedication to fortify children's mental well-being, bolstering self-regulation, and providing AI-infused, personalized cognitive training. With Neuromindset, education it's not just about learning—it's about flourishing in every sense.

Arman Anatürk is Co-Founder @ FoodHack.

Investment focus

Biotechnology, Food and Beverage, Wellness
Seed, Pre-Seed
Spain, Israel, Germany

Portfolio highlights

Bosque Foods — Kinoko Labs develops the next generation of meat substitutes, starting with whole-cut meat items made from fungal mycelium produced organically. Headquartered in New York.
Libre Foods — MEAT, BUT MAKE IT MUSHROOMS. GET READY TO TASTE THE POWER OF FUNGI
Kynda — Keen 4 Greens offers a wide range of vegan products. Founded in 2019, Keen 4 Greens is based in Hamburg, Germany.

I am a food scientist, entrepreneur and investor. Through SFV (sustainablefoodventures.com), I back founders building the future of cell-based, plant-based and recombinant food.

Investment focus

Food Processing, Seafood, Wellness
Pre-Seed, Angel
Spain, Iceland, United States

Portfolio highlights

Loki Foods — We're producing sustainable, plant-based foods from the Arctic. Iceland’s first plant-based cod and seafood!
Sobo Foods — Sobo Foods is a plant based comfort food provider.
Libre Foods — MEAT, BUT MAKE IT MUSHROOMS. GET READY TO TASTE THE POWER OF FUNGI

Originally studying medicine in Scotland, John is a pioneer of the Australasian medical recruitment industry and has over 20 years of experience growing his award-winning business, Wavelength International, from two founders to over 100 staff. Moving to Europe in 2012, John worked initially for an equity crowdfunding business focused on raisingseed funds for European life sciences start-ups, before launching the Luka Global Group, including LUKA BIO, with the co-founders in 2019. John provides guidance and mentorship to start-up founders on how to set up their own in-house recruitment capabilities in preparation for growth. His recruitment portfolio includes C-suite, medical and research roles within life sciences.

Investment focus

FinTech, Medical, Life Science
Debt Financing
Spain

Portfolio highlights

Capital Cell — Capital Cell is a pan-European crowdinvesting platform for Biotech & Life Sciences companies. Mixing VC, business angels, accredited investors and the power of the Crowd, the company is building a global meeting point for companies and researchers working, fostering and financing tomorrow’s medical science.

Arturo Elizondo is CEO of Clara Foods, a sustainable ingredients company making the world’s most comprehensive egg white substitute. Clara leverages advances in fermentation technology to bring an egg white to the table that is completely animal-free, far more sustainable, and free of salmonella without compromising the qualities we know and love.Prior to joining Clara Foods, Arturo worked at the investment bank Credit Suisse, U.S. Department of Agriculture, and under Supreme Court Justice Sonia Sotomayor.

Investment focus

Wellness, Life Science, Biotechnology
Seed, Pre-Seed
Spain, Switzerland

Portfolio highlights

Libre Foods — MEAT, BUT MAKE IT MUSHROOMS. GET READY TO TASTE THE POWER OF FUNGI
Cultivated Biosciences — Cultivated - Creamy, dairy-free indulgence

Others Others

Investment focus

Biotechnology, Software, B2B
Seed, Pre-Seed, Funding Round
Spain, Germany, Ireland

Portfolio highlights

Conektto — Design, Build & Test API in minutes. Conektto is the industry's first API SDLC platform that intelligently generates artifacts.
Gheorg — Around 1 million children in Australia have diagnosable anxiety. Two-thirds of them will never get the help they need. Gheorg is on a mission to change that. We're aiming to reduce childhood anxiety and our new app helps parents and children at home. Sign up to get the app on our website.
Hooke Bio — Hooke Bio is a new Pharmaceutical company operating in the preclinical to early stages of drug discovery. It draws its strength from the close co-operation it has between its biologists and engineers. The engineers design, patent and test new microfluidic technology: the scientists apply the technology to finding new therapeutics.

Javier Alsina

Investment focus

Health Care, Neuroscience, Biotechnology
Seed
Spain

Portfolio highlights

FreeOx Biotech — Based on the knowledge of oxidative stress and uric acid, Freeox Biotech is developing neuroprotective therapies to reduce the damage resulting from ischemia and in this way improve the recovery of the patients. Ox-01 is Uric Acid used as a medicinal product. Ox-01 has a proven effect in preventing the damage caused by reperfusion after stroke.Ox-02 Uricoline is a molecule resulting from the association of Ox-01 and Citicoline. Citicoline is an intermediate in the generation of phosphatidylcholine from choline.