Top 5 Enterprise Angel Investors in Puerto Rico (October 2026)

Portfolio highlights

• CASIMIR —
• illumicell AI — illumicell AI combines patented AI algorithms and proprietary microscopy technology to test 50x faster, 20x more effectively, empowering every healthcare provider at the point of care – not just fertility clinics – with accessible, scalable fertility diagnostics.
• SignalRank — SignalRank owns a growing asset portfolio of top performing venture backed companies. It enters at Series B by helping early stage investors maintain their ownership in their best assets. The resulting portfolio is a top decile venture performer since inception in May 2023. SignalRank finances early stage investors’ pro-rata in qualifying Series B rounds through an automated process designed for speed, high-conviction selection, and partner-aligned economics. it can decide inside 24 hours and fund in less than a week. As a result SignalRank has 300+ seed partners who invite it to partner for pro-rata financing in their fastest growing companies. It sees a high percentage of all Series B term sheets prior to close. Capital is supplied from SignalRank’s balance sheet, with no capital calls or partner IC process delays. Check size correlates with capital available. SignalRank handles SPV setup and ongoing administration, with a target of moving from partner allocation request to funding in 5 business days. 20% of the profit on each investment goes directly to partners. SignalRank creates deal-by-deal SPVs; SignalRank does not charge management fees for this partner product. The portfolio can be seen at - https://signalrank.com/signalrank-index.html

Portfolio highlights

• Nada — Finance, Invest and Bank your real estate.
• DigiBuild — Automate your construction supply chain with AI.
• Upright — Meet Upright, the good for you go-to. Our first product is a category-defining high-protein, allergen-free Instant Oatmilk in three creamy, delicious flavors: original, vanilla, and chocolate. Each tasty cup of our oatmilk packs the same key nutrients as dairy, without the unwanted allergens or environmental impact.

Portfolio highlights

• Docker — Docker is a platform designed to help developers build, share, and run container applications. We handle the tedious setup, so you can focus on the code.
• Aleo — Welcome to Aleo. The first platform for fully private applications. Write, run, and host private applications on Aleo. The ultimate toolkit for building private applications is finally here.
• Badger DAO — A community of builders bringing Bitcoin to DeFi

Portfolio highlights

• RED Atlas — RED Atlas offers a platform that gives real estate data and insight to people working in the property market. It provides tools that let professionals find detailed information about individual properties and trends in the market. Atlas Professional is a product on the site that gives real-time property data, news, and analytics for brokers,investors, and agents. The platform lets users search property records and generate reports that help in planning and decision-making. It makes it possible for people to filter property information and create lists that fit specific needs. The service also supports sharing property details in formats that others can review.
• Alife — Alife is building technology for both clinics and patients.
• Druid Software — Druid are the leading provider of Private 5G Networks, Private 4G Networks and LTE Private Networks with their Private Core Network Platform Raemis.

Portfolio highlights

• RED Atlas — RED Atlas offers a platform that gives real estate data and insight to people working in the property market. It provides tools that let professionals find detailed information about individual properties and trends in the market. Atlas Professional is a product on the site that gives real-time property data, news, and analytics for brokers,investors, and agents. The platform lets users search property records and generate reports that help in planning and decision-making. It makes it possible for people to filter property information and create lists that fit specific needs. The service also supports sharing property details in formats that others can review.
• Nauta — The AI company brain that learns how you work and powers agents in procurement, logistics, sales and finance.