Top 45 Cryptocurrency Startup Investors in Mexico (September 2026)

Portfolio highlights

• TurboFlow — Trading, made simple. Everyone gets a seat at TurboFlow.
• DePay — DePay is an Argentina-based real-time payments infrastructure startup.
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.

Portfolio highlights

• Duppla — Duppla operates as a rent-to-own startup focused on providing alternative financing solutions for home buyers in Colombia. It offers a unique approach to homeownership, where traditional debt is not the primary mechanism. Instead, Duppla presents an innovative model that facilitates access to housing through alternative financing methods. Thisapproach is designed to make the dream of owning a home more attainable for individuals and families, particularly in the LATAM region. With a team that includes co-founders and experts with backgrounds in research and strategy from notable companies, Duppla leverages its understanding of organizational context and user experience to tailor its services. The company aims to address the challenges of affordable housing financing, making it easier for customers to navigate the path to homeownership.
• Xepelin — Xepelin is a fintech company that offers a SaaS platform for small and medium-sized businesses in Latin America that can organize their financial information in real-time. It seeks to simplify access to capital for its clients by creating a Simple, Fast, and Safe experience. The company was founded in 2019 and is based in Las Condes, Chile.
• Ábaco — Ábaco is a fintech company that offers financial services with capital, payments & platform solutions.

Portfolio highlights

• Goin — Goin is a Barcelona-based fintech platform founded in 2017 that provides a unified money optimization ecosystem combining automated savings, investments, digital assets, and rewards. The app enables users to aggregate multiple bank accounts via PSD2, centralizing financial data and automating decisions through its AI engine, gaIA. Goin integratesfinancial automation, portfolio tools, and cash-back incentives in a single interface used primarily by young European consumers. The company operates in a regulated environment, is registered with the Bank of Spain as a crypto service provider, and has expanded across Southern Europe. In 2025, Goin launched KernelPay, its B2B Banking-as-a-Service (BaaS) infrastructure for payments, accounts, and wallet management.
• Rain — Rain is a vertically integrated issuing partner for global platforms. Enabling innovative financial products through modern APIs, flexible infrastructure, supporting electronic and digital money. Launch a card program in days not months.
• Terminal 3 — Trusted identity & security for an agentic future.

Portfolio highlights

• Laevitas — Laevitas is a data analytics platform based on quantitative finance models for the crypto-asset market. The company aims to provide analysis by implementing mathematical models on data from a variety of crypto-asset derivatives markets
• Delio — Crypto Financial Services Provider
• Orderly Network — Launch and operate a perpetual DEX with shared liquidity, omnichain infrastructure, and builder-owned fee revenue.

Portfolio highlights

• Suzaku — The Decentralization Hub for L1s. Everything staking on @avax. Blockchain services provider via @ash_avax
• E36 Knots — E36 Knots build decentralized web3 services with the goal of empowering developers and users
• Geode Finance — Geode Finance is a first of its kind white label liquid staking solution, tailor-made for DAOs.

Portfolio highlights

• SPAKIO — SPAKIO is a one stop shop solution to store physical items that lets you manage them as if they were digital. We pick up, store, and then deliver any item
• Hero Guest — Hero Guest is a digital platform focused on evolving restaurants’ experiences. It improves business profitability through empowered staff, engaged customers, and strategic data. It was founded in 2015 and is based in Lomas de Chapultepec, Mexico.
• 1Money Network Technologies — 1Money Network Technologies is a payment network dedicated to stablecoins.

Portfolio highlights

• SOND — Revolutionary sleep technology for optimal wellness and enhanced daily living. The first phone-free AI sleep coach with smart ANC earbuds.
• Adaption Labs — Adaptation creates AI systems that adjust to changing real-world circumstances.
• Subconscious — Subconscious Systems builds infrastructure that makes large language models faster, cheaper, and more reliable to run at scale. Its platform combines a custom inference runtime with model-driven agent capabilities that handle context management, reasoning, and tool use automatically. Customers use Subconscious to deploy production-grade AI agentsthat stay coherent across long workflows and operate efficiently on existing hardware. The company originated from MIT research and serves developers and enterprises building advanced AI applications.

Portfolio highlights

• Sourcepulse — Your early warning system for software delivery (YC S23)
• Hypercubic — Hypercubic is agentic AI for mainframe modernization, helping enterprises and governments preserve institutional knowledge and modernize COBOL.
• NORDA Dynamics — NORDA Dynamics is an autonomous UAV piloting system for carrying out missions in areas with limited connectivity.

Portfolio highlights

• Sapiom — The platform vertical AI companies build, ship, and scale agentic products.
• City Protocol — City Protocol offers growth incentives and creative tools driven by AI. A portable reputation is created via City ID.
• Velocity — Velocity provides a unified platform for efficiently moving and managing funds across both traditional banks and blockchains.

Portfolio highlights

• Mento Labs — Mento is bringing FX onchain. We provide institutions with access to onchain FX at real-world rates.
• Learn.xyz — Learn.xyz’s is a mixture of Duolingo and Wikipedia, powered by AI, creating bite-sized “Curiosities” which feature slides and a quiz, in mere seconds just from taking in a user’s question. Find the app on iOS and Android.
• Thrive Protocol — Thrive Protocol's vision is to maximize value creation for all people and communities.

Portfolio highlights

• Row64 — Row64 is the world’s first Data Science Spreadsheet powered by a GPU data engine that runs 10x to 1,000x faster than traditional data software. Designed ground up for Business Analysts & Data Scientists, Row64 blends the simplicity of Excel with the Power of Python to accelerate your data pipeline. Row64 works interactively with billions ofrecords, delivers keynote quality storytelling tools and one-click Data Science recipes to spreadsheet users.
• Last Energy — Last Energy develops and delivers micro modular nuclear power plants designed to provide decarbonized, reliable energy through a full-service delivery model that spans design, construction, and operations. The company offers factory-produced modular plants, like its 20 MWe PWR-20 units, that can be deployed rapidly to serve energy-intensiveindustrial customers and utilities with baseload electricity and heat. Its services include long-term power purchase agreements that eliminate upfront capital for customers while enabling flexible siting and minimal resource requirements. Last Energy’s solutions support both behind-the-meter applications for industries and grid-scale energy projects for broader power delivery. The company integrates established reactor technology with its delivery process to help clients access consistent, carbon-free energy.
• Commonwealth Fusion Systems — The fastest path to clean, limitless fusion energy.

Portfolio highlights

• Starcloud — Starcloud is building a network of megawatt-scale data centers in space, scaleable to gigawatt capacity. Falling launch costs allow Starcloud to take advantage of the abundant energy, passive cooling, and high-speed connectivity in space.
• modus — Modus - The Context Warehouse for Enterprise AI. Automatically mine, compose, and deliver intent-based context to any AI platform. Backed by Insight Partners.
• Cambium — Cambium Carbon is an early stage social enterprise start up focused on implementing systems-level natural climate solutions centered on reforestation and urban wood reuse.

Portfolio highlights

• Zhihuige — Zhihuige is as an AI customer service developer specializing in the e-commerce sector. The company focuses on providing AI-powered customer service solutions for e-commerce platforms, leveraging advanced artificial intelligence large model technology and proprietary natural language processing (NLP) algorithms.
• Dora Factory — Dora Factory is the digital infrastructure builder of the Global Hacker Movement. It creates protocols, toolings, and public good infrastructures that help open source communities and frontier tech builders to thrive.
• Pando Finance — Pando Finance is a licensed institution that provides investment solutions to corporate and individual investors. I t provides asset management, trading and advisory.

Portfolio highlights

• Bitso — Invest in crypto, bitcoin, ethereum, and global stocks. Earn yields, send, and receive money securely with Bitso. Join millions, growing their money with one powerful app.
• ErisX — Improving the digital asset trading experience for institutions and individuals alike.
• kubo.financiero — Kubo.financiero is the only 100% digital regulated finance company in Mexico. It offers savings accounts, personal loans and term deposits to its clients. Kubo’s lean model allows for lower interest rates for borrowers and higher return rates for depositors and investors. Its innovative model and strategic approach aim to encourage a “multipliereffect” to generate and strengthen Mexico’s emerging middle class through customer-centered financial services.

Portfolio highlights

• Jiko — Jiko is a new type of bank built on US Treasury bills to unlock unprecedented yield, safety, and scale through direct products and an embedded finance API. Jiko removes the limits of traditional banking to create a new paradigm for building financial success at the scale and speed of today’s economy. Headquartered in San Francisco with offices inNYC and Reykjavik, Jiko's vertically integrated financial institution combines its nationally chartered bank and registered broker-dealer to hold cash as T-bills – all in safe custody. Learn more at www.jiko.com.
• Lumx — Stablecoin payment infrastructure for LATAM. API for global pay-ins, payouts, multi-currency accounts, and custody. Built for neobanks, exchanges, importers, exporters, and payment providers.
• Latitude — Latitude is working on a global payments system that links stablecoin-based settlement with local currency payout systems.

Portfolio highlights

• Ozone — Meet Ozone, your AI-powered video editor.
• Ozone — Meet Ozone, your AI-powered video editor.
• Integrated Biosciences — Integrated Biosciences is the first company in history to be able to virtually stress cells.

Portfolio highlights

• ORKID — ORKID is a B2B company that offers last mile and middle mile drone delivery technology and services to enterprises. Our autonomous electric drones offer a faster, more affordable, and sustainable alternative to traditional delivery methods.
• Ubanku — Tus finanzas simples, organizas y lejos de la inflacion
• ROOK — RookMotion offers heart rate monitoring technology based on effort zone training for you and your fitness business. Train smart and reach the next level.

Portfolio highlights

• Epirus — Epirus is a high-growth technology company that develops cutting-edge directed energy systems and power management solutions to transform multiple industries.
• BQP — At BQP, we’re developing a quantum-accelerated digital twin platform for mission-critical applications. The platform, BQPhy, is a back-end engine that integrates seamlessly into existing engineering workflows and operates on today’s infrastructure without requiring quantum hardware. BQPhy helps teams solve large-scale, complex challenges inengineering optimization, data-driven modeling (ML), and physics-based (CFD) simulations. We are bridging the gap between current high-performance computers and future quantum systems with probabilistic algorithms from quantum information science, unlocking simulation capabilities that were previously impractical or impossible. BQPhy reduces time, accuracy, and throughput inefficiencies, thereby accelerating development cycles, unlocking previously unexplored design spaces, lowering costs, and enhancing product outcomes.
• Sharper Sense — Neuromodulation for Clear Senses

Portfolio highlights

• Suncolombia — Suncolombia is a renewable energy company that provides solar solutions.
• Enel Colombia — Enel Colombia is an energy trading company that generates, markets, and distributes electricity.
• Santander Electrification Company — ESSA (Santander Electric Company S.A. E.S.P.) generates, transmits, and distributes electricity. It operates power generation plants and manages energy distribution networks. The company provides electricity services to residential, commercial, and industrial customers.

Portfolio highlights

• ARPA — ARPA is a network that provides secure computation, which enables data to be shared and used without disclosing the raw data to anyone during data-at-use. The correctness of computation is verifiable even under majority malicious condition using Information-theoretic MAC and Zero- Knowledge Proof. By using state-of-the-art Multi-party Computationalong with innovative node communication scheme, our privacy-preserving computation protocol enables a new way of data monetization called Data Renting.
• ARPA Network — ARPA Network is a decentralized computing network designed to improve the fairness, security, and privacy of blockchain technology.
• Sanctum — Stake SOL and earn optimized LST returns from JupSOL, bbSOL, and more, and launch your own custom LST and Solana validator.

Portfolio highlights

• MixMob — A P2E Game on Remix Culture. grab your mask and start your journey - level up from card strategy battle game to full MMO glory!
• Freatic — Building the monetization layer for your alpha
• Encode Club — Learn crypto with our web3 education community. Get learning. Get building. Get hired. Get funding.

Portfolio highlights

• Robbin — Robbin is leading a revolution to change how 21 million SMBs fund $2.5 trillions in B2B Payments. Employing an innovative underwriting approach, Robbin leverages BRL 3 trillion in card receivables as collateral to underwrite a one-of-a-kind business credit card for underserved entrepreneurs.
• Telepatia — Telepatia is a health tech platform that utilizes artificial intelligence to support medical professionals.
• Karta — The premium US charge card for the world's borderless people. Credit lines up to $200,000 based on your US assets. No Social Security number required.

Portfolio highlights

• Cuidefy — Cuidefy is a platform aimed at connecting families with trusted caregivers for children, the elderly, and pets.
• IUS.Earth — IUS.Earth offers a comprehensive and advanced solution for SMEs, sustainability, environmental management, and strategic intelligence.
• Quipu Bank — QUIPU consists in a platform that enables digital local markets in informal settlements, using blockchain applications.

Portfolio highlights

• Regent — We build all-electric, passenger-carrying, wing-in-ground-effect vehicles to service coastal routes with technology available today.
• Antares — Factory-produced, deployable fission microreactors to provide strategic energy for mission-critical systems across Earth, space, and underseas.
• Gravity — The Ad Network for AI

Portfolio highlights

• 375ai — 375ai is an edge data intelligence network on Solana that provides advanced real-time data collection and analysis to power a smarter, more connected world.
• Power Protocol — The ecosystem for blockchain entertainment. Fueled by $POWER. Launch Partner: @Fableborne Power Up Your Play
• Hyperdrive — The liquidity layer for RWAs. Scaling lending by eliminating the need for oracles, AMMs, and external liquidators.

Portfolio highlights

• SYNTRA — Live AI trading system. Real-time execution, risk-managed positions, public trade feed. Signals, performance, transparency.
• Vue Protocol — Community-First Layer for AI Memecoins. @solana @pumpdotfun @ton_blockchain Dvo1Fb7FxtUxsLbcQaizftfUT9HtL9P6swaQAScZDeQQ
• Pichi Finance — Pichi Finance Points are typically stored off-chain and linked to wallet addresses, limiting their tradability on the open market.

Portfolio highlights

• Kontigo — We help underbanked gig workers in Latam build credit and access group financing where small groups of family or friends lend and save money together. Users can validate their income from multiple sources such as gig apps, catalog sales, and open finance (Uber, Rappi, Didi, Indriver, Avon, and all major banks). After verifying the income wedirectly offer them group savings and group loans, without leaving WhatsApp, their primary messaging app.
• Subzero Labs — Subzero Labs is developing Rialo, a developer-first Layer 1 blockchain built for internet-scale decentralized applications.
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.

Portfolio highlights

• Vangrid — Vangrid operates as a decentralized physical infrastructure network.
• Slinky Network — Slinky Network provides an on-chain marketplace and payment protocol that connects AI agents and applications with third-party APIs. The company offers the SlinkyLayer platform, which wraps developer endpoints as discoverable skills and exposes them through an x402 pay-per-execution interface. Each API call triggers a non-custodial on-chainmicropayment, settling in the same request loop using networks such as Base and BNB Chain. Developers set prices, earn a defined revenue share, and receive instant payouts to their wallets without subscriptions or custodial holds. AI agents authenticate via wallet signatures, enabling autonomous, machine-to-machine access and payment without traditional logins or credit cards. The platform also records call ratings on-chain to provide portable, verifiable reputation for services.
• Ceramic Network — We've joined @textileio to build the first open intelligence network for AI agents. Follow us there.

Portfolio highlights

• HUNTY — HUNTY is a platform that help people find jobs by connecting them with world class mentors who prepare them for the job search process. And people only pay when they get hired.
• Lastro — Lastro is building Lais, an autonomous AI worker for real estate agencies, starting in Brazil. Our AI agent initially automated lead engagement and qualification via WhatsApp, helping brokerages boost revenue and improve marketing ROI. In each brokerage, Lais acts as a personalized AI “team member” that engages with leads instantly, searches forproperties and answers common inquiries. Brokerages that have Lais in their teams are growing quickly and reporting up to 60% increases in lead conversion rates.
• Wash Wise — Meet Reset Spray: the dry shampoo for clothes. Refresh lightly worn garments in seconds by neutralizing odors, lifting away sweat and body oils, and releasing wrinkles between washes.

Portfolio highlights

• AllScale — AllScale is a next-generation platform empowering small businesses to scale globally faster with stablecoin. Payroll: Automate cross-border payroll in stablecoins—simplify contractor payments, eliminate costly intermediaries, and ensure instant global delivery.Invoicing: Create, e-sign, and send professional contracts and invoices in seconds.Get paid by clients in their preferred method and instantly receive stablecoin—maximizing liquidity, minimizing friction.Social Commerce: Transform your followers into customers. Embed a dynamic AllScale biolink on your social profiles, showcase your offerings, and securely collect instant stablecoin payments directly from your audience.
• Voyage — The full stack AI GTM solution. We help your brand grow on autopilot.
• Swarm Network — Agentic infra for the future $TRUTH NEW: Build your Future agent teams in beta

Portfolio highlights

• Simetrik — Automate repetitive data reconciliation processes without any coding knowledge
• Simetrik — On a mission to bring transparency and trust on business data by empowering people with technology.
• numia — numia (formerly Debmedia) is a B2B SaaS platform that helps industries manage customer journeys by seamlessly integrating online and offline experiences. By combining AI automation with human interaction, numia assists companies—including leading banks, insurance firms, telcos, healthcare providers, and retailers—to boost sales, optimize customerengagement, and enhance customer satisfaction.

Portfolio highlights

• sevDesk — Deutschlands beliebteste Buchhaltungssoftware: Rechnungen& Angebote erstellen, Buchhaltung erledigen, Kunden- &Lagerverwaltung u.v.m.
• Cambridge Aerospace — Our mission is to eliminate the risk of existential war in Europe.
• Arrakis Technologies — Arrakis partners with ambitious companies to deploy secure AI in production, taking them from experimentation to real-world impact at warp speed.

Portfolio highlights

• Humanoid — Humanoid creates advanced humanoid robots that integrate seamlessly into daily life, enhancing human potential. Learn more about our mission and vision.
• Attention — Attention is a powerful conversational intelligence software that helps you coach and ramp up your sales reps into top performers.
• Primepoint — Primepoint is the construction AI platform trusted by leading GCs. Connect documents, catch conflicts before the field and get instant answers traced to the exact drawing or spec.

Portfolio highlights

• iPNOTE — The iPNOTE AI paralegal manages the entire IP registration workflow: answers attorney questions, reviews deliverables, summarizes documents, tracks deadlines, sends follow-ups to providers, monitors progress from filing to grant, and processes payments. Your team interacts with one intelligent agent that smoothly coordinates with patent attorneysworldwide - turning weeks of manual work into automated efficiency.
• Fineksi — Finskor memiliki misi untuk menjadi penyedia terkemuka layanan penilaian kredit yang akurat dan andal, membantu bank dan lembaga keuangan lainnya untuk membuat keputusan kredit berdasarkan analisis data yang komprehensif.
• Kontigo — We help underbanked gig workers in Latam build credit and access group financing where small groups of family or friends lend and save money together. Users can validate their income from multiple sources such as gig apps, catalog sales, and open finance (Uber, Rappi, Didi, Indriver, Avon, and all major banks). After verifying the income wedirectly offer them group savings and group loans, without leaving WhatsApp, their primary messaging app.

Portfolio highlights

• AfterHour — Join the best stock trading community with over $200M+ in verified positions from retail traders. Get trade signals, due diligence, and real-time alpha.
• Astrocade — Create, share, and play casual games with friends. No coding, no downloads. Just make something that millions of people can play.
• Atlas Invest — Commercial real estate bridge loans up to $20M with same-day term sheets and funding in as few as 7 days. Institutional private credit for investors.

Portfolio highlights

• SPAKIO — SPAKIO is a one stop shop solution to store physical items that lets you manage them as if they were digital. We pick up, store, and then deliver any item
• Mattilda — Mattilda is the only one-stop-shop solution for LatAm private schools, dedicated to easing the operating and financial issues of schools through an AI powered system of record. It provides access to automated collection management products, payment aggregation services, revenue factoring, a specialized CRM, operating AI agents, medium and long-termcredits and a student information system to help them solve their everyday problems while focusing on the most important thing; providing high-quality education. It operates across Mexico, Colombia and Ecuador and serves +415k students.
• Relay Response — Modern CPR training with real-time feedback, group workflows, and dashboards. Be the person who knows what to do.

Portfolio highlights

• Mara — autonomous horde of the free world
• Beglaubigt.de — https://t.co/BCWk4L679n ist die erste Plattform zur Digitalisierung des Notariats in Europa.
• ZeroSettle — Zerosettle offers a merchant web checkout software for iOS apps to process payments, manage tax, and handle compliance and disputes.

Portfolio highlights

• OpenEx — OpenEx is a cutting-edge, user-focused exchange that seeks to transform the cryptocurrency market. We offer a platform that is user-friendly for beginners and emphasizes user empowerment and freedom while ensuring honest transactions and individualized services.
• GAMES.GG — Discover 1,500+ games with honest reviews, expert guides, and daily gaming news across PC, console, and mobile. Find your next favorite game on Steam, Epic Games, PlayStation, Xbox, and Nintendo.
• VelaFi — Galactic Holdings offers a series of digital finance products.

Portfolio highlights

• NxThera — NxThera develops medical technologies to treat a variety of endourology conditions, including BPH. The company's technology platform utilizes a simple, minimally invasive, vapor therapy designed to measurably improve urinary flow and patient quality of life. BPH afflicts more than 32 million men in the United States.
• VelaFi — Galactic Holdings offers a series of digital finance products.
• Kailera Therapeutics — Focused on elevating the next era of #obesity care by advancing a diversified pipeline to provide options for people living with obesity. #KaileraTx

Portfolio highlights

• Blitzy — You Describe It, We Build It
• Oxmiq Labs — Licensable GPU IP and a unified runtime for the age of inference. OXMIQ Labs is re-architecting the GPU stack from atoms to agents.
• Venice — Private & Unrestricted AI | https://t.co/iIt1pyF1TK

Portfolio highlights

• June — Transform enterprise system deployment with June. AI-driven implementation for Salesforce, Snowflake, SAP & more. No downtime, faster delivery, full control.
• Foundation Industries — Foundation Industries provides manufacturing technology and services focused on fast, low-volume, high-mix CNC machining for hard tech companies. The company offers an online portal where engineering teams can upload designs, define specifications, and receive transparent quotes for custom components. Its system supports domestic production runswith turnaround times as short as two days for qualifying orders. Foundation Industries focuses on helping hardware teams move efficiently from design to production by simplifying quoting, ordering, and tracking in one place. The company serves deep tech and physical engineering organizations that need rapid prototyping and small-batch production of precision-machined parts. Its services are intended to reduce lead times, increase predictability, and support the development and launch of complex hardware systems.
• Foundational Industries — Foundational Industries develops, finances, and operates autonomous manufacturing facilities for contract manufacturing. Its factories use AI-enabled robotics and a unified factory operating layer to coordinate activities from product design through production. The company serves businesses that require domestic production and manufacturingcapacity for critical components and products.

Portfolio highlights

• LiveArtX — LiveArtX is a premium NFT platform that connects the art world with web3. Built by art industry leaders, LiveArtX brings creators, collaborators, and collectors into the metaverse.
• OSL — OSL is a regulated global platform for stablecoin trading, payments and digital asset infrastructure. Secure, compliant and institutional-grade.
• VelaFi — Galactic Holdings offers a series of digital finance products.

Portfolio highlights

• Ferra — @ferra_xyz is now @ferra_protocol
• Datagram — Datagram is an AI-driven, decentralized infrastructure platform operating as a DePIN baselayer. The company provides a live, scalable node network for launching custom DePIN networks and real-world decentralized applications, with cost savings over traditional cloud providers.
• Noodles Finance — The no-brainer trading platform for Sui.

Portfolio highlights

• Kapkap — Kapkap is a web3 platform that uses AI for attention based value distribution in gaming.
• SuperIntent — SuperIntent is a cryptocurrency AI app that streamlines on-chain earning tactics. Developed on a multi-agent framework with abundant yield sources.
• Inference Labs — AI hyperscale on decentralized networks - We provide certainty for on-chain AI

Portfolio highlights

• Meshy AI — The #1 3D GenAI platform—trusted by millions worldwide. The ONLY 3D AI tool featured in A16Z's 2024 AI Tools Survey.
• Stavko — Stavic is a manufacturing services company that specializes in the production of computers, communication devices, and other electronic equipment.
• Shumeiwuwu — Shumeiwuwu is a cross-border e-commerce company that provides quality goods and services to consumers through global shopping.