Top 5 Health Care Angel Investors in Isle of Man (June 2026)

Jim Mellon is an international investor with interests in several industries. After leaving Oxford, where he studied PPE, (Philosophy, Politics and Economics) he worked in Asia and the United States for two fund management companies, GT and Thornton, before establishing his own business in 1991. His business operations include two components, alisted fund management company called Charlemagne Capital, and an Asian mining group, Regent Pacific.In addition, Mr. Mellon is Co-Chairman of West African Minerals Corporation and Regent Pacific Group. He is on the board of a number of public quoted companies, including Brazilian Gold Corporation, Charlemagne Capital Limited, Manx Financial Group, Plethora Solutions, Polo Resources, Port Erin Biophara Investments Limited, and the Speymill plc. He is the life tenant of a trust which owns the Burnbrae Group, which has substantial assets in the biotechnology, financial services, property, mining and leisure sectors. Mr. Mellon spends most of his time working on startup ideas and investing. His book, “Wake Up!” was published in 2005; his second book "10 Investments for the Ten Years Ahead" was published in 2008. In 2012, he co-wrote "Cracking the Code" which focuses on the biotechnology sector and how to profit from it. Mr. Mellon lives in the Isle of Man, Brussels and Ibiza and is an honorary fellow of Oriel College, Oxford.

Investment focus

Industry: Biotechnology, Food and Beverage, Health Care
Stage:Series A, Seed
Geography: United States, United Kingdom, Israel

Investor stats

Total investments: 32
Round size: Seed $536k–$20M; Series A $4.6M–$46M
Lead/follow: 41% lead, 59% follow

Portfolio highlights

OncoSenX — OncoSenX is a developer of transient gene therapies designed for solid tumors. The company's therapy delivers plasmid DNA with a novel lipid nanoparticle that selectively kills cancerous cells based on their transcriptional activity, providing cancer patients, doctors and medical care professionals with a less invasive and more preciseintervention for this complex and devastating disease.
Netwealth — Netwealth provides expert investment management and tailored wealth planning solutions, helping you confidently achieve your financial goals.
Repair Biotechnologies — Repair Biotechnologies is a developer of clinical gene and protein therapies intended to focus on the reversal of age-associated thymic atrophy and consequent loss of immune function. The company's platform is committed to developing treatments for ageing and age-related diseases that address the root causes of these conditions, enabling humanbeings to improve their health span through targeting the causes of age-related diseases and ageing itself.

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Mark Wilkinson is an English-Australian singer-songwrite.

Investment focus

Industry: Alternative Medicine
Stage:Seed
Geography: Isle of Man

Investor stats

Total investments: 1
Lead/follow: 0% lead, 100% follow

Portfolio highlights

GrowLab Organics — GrowLab Organics is a medical cannabis company to increase access, affordability, choice, and quality while building an inclusive and community-owned business that acts as a positive force for change.

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Dr. Gregory H. Bailey is a Managing Partner at Palantir Group, Inc. Dr. Bailey is the Co-founder of Ascent Healthcare Solutions; VirnetX Inc. (AMEX:VHC) and Duramedic Inc. He was also the initial public financier and an independent director of Medivation, Inc. (NASDAQ:MDVN), from 2005 to December 2012. Dr. Bailey served as the Managing Director andco-Head of Life Sciences at MDB Capital Group LLC from May 2004 to January 2007. Previously he served as Life Sciences Analyst at Participating Capital, Corp. He has served on the board of directors of multiple public companies. Dr. Bailey has Medical Doctorate from the University of Western Ontario and practiced medicine as an emergency physician for ten years.

Investment focus

Industry: Biotechnology, Pharmaceutical, Health Care
Stage:Series A, Post-IPO Equity, Seed
Geography: United States, Isle of Man

Investor stats

Total investments: 9
Round size: Series A $3M–$19M; Post-IPO Equity $15M–$80M
Lead/follow: 44% lead, 56% follow

Portfolio highlights

Juvenescence — We extend healthy lifespan through developing innovative medicines that target core aging mechanisms to not only treat but prevent age-related diseases.
Serina Therapeutics — Serina Therapeutics is a privately-held pharmaceutical company that is advancing novel therapeutics for cancer, inflammation, pain, and metabolic disorders using its proprietary polymer technology. They have created new pharmaceutical candidates using polyoxazoline (POZ), a safe, water-soluble polymer to which they can attach a variety of smallmolecules, proteins, peptides, and DNA. The attachment of these molecules to polymers of POZ typically confers a unique pharmacokinetic profile that is markedly different from the parent compound, and this profile may confer advantages in terms of safety and efficacy.
Bristol-Myers Squibb — Bristol Myers Squibb is a global biopharmaceutical company committed to discovering, developing and delivering innovative medicines to patients with serious diseases.

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Andrew Banks - Chairman and Co-Founder @ ABRY Partners

Investment focus

Industry: Biopharma, Biotechnology, Pharmaceutical
Stage:Seed
Geography: Isle of Man

Investor stats

Total investments: 1
Lead/follow: 0% lead, 100% follow

Portfolio highlights

Juvenescence — We extend healthy lifespan through developing innovative medicines that target core aging mechanisms to not only treat but prevent age-related diseases.

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