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Longwood Fund, VC Fund

Longwood Fund

VC Fund

Boston, United States

Longwood Fund is a VC fund in Boston focused on Biotechnology and Health Care. Longwood creates and invests in science-based companies that develop novel solutions for important medical problems

Total investments:
81
Last investment:
Lead investor:
17%
Fund size:
$158M
Last fund:

Last updated:

Industries Longwood Fund invests in

BiotechnologyHealth CareTherapeuticsLife SciencePharmaceutical

Stages Longwood Fund invests in

Series ASeries BSeries CVenture - Series UnknownSeed

Countries Longwood Fund invests in

United StatesUnited KingdomItalyBelgium

Round sizes

Series A $16M–$100MSeries B $30M–$141MSeries C $17M–$100M

Contacts

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Round size

Series A
$16M–$100M
Series B
$30M–$141M
Series C
$17M–$100M

Investment Focus

Industry

  • Biotechnology 42 (52%)
  • Health Care 26 (32%)
  • Therapeutics 24 (30%)
  • Life Science 17 (21%)
  • Pharmaceutical 15 (19%)
See all 25 industries →

Stage

  • Series A 28 (35%)
  • Series B 21 (26%)
  • Series C 9 (11%)
  • Venture - Series Unknown 6 (7%)
  • Seed 1 (1%)
See all 7 stages →

Country

  • United States 44 (54%)
  • United Kingdom 3 (4%)
  • Italy 1 (1%)
  • Belgium 1 (1%)

Team

NameTitleInvestmentsLinksEmail
Partner Total investments: 1
Find email
John McCabe
John McCabe Operating Partner
Operating Partner Total investments: 0
Find email
Manager Total investments: 11
Find email
David Donabedian
David Donabedian Executive Partner
Executive Partner Total investments: 2
Find email
David Donabedian, PhD
David Donabedian, PhD Venture Partner
Venture Partner Total investments: 1
Find email
See all 7 team members →

Investments

CompanyDescriptionRoundLinks
Khartis is a drug discovery company developing oral therapies for patients with immune-mediated and chronic diseases. The company focuses on discovering and developing drug candidates intended to address chronic conditions and immune-mediated diseases. $50M / Series B / Aug 13, 2026
Coultreon Biopharma is developing best-in-class therapeutics that target clinically validated pathways in immunology and metabolic illnesses.Coultreon Biopharma employs extensive experience in disease biology, drug development, and translational science to identify the optimum treatment approach for addressing underlying illness biology withbest-in-class therapeutics. $125M / Series A / Apr 28, 2026
Neomorph is building a leading protein degradation entity, focused on “molecular glue” degraders. Its mission is to use this technology to solve critical problems in human health with the discovery and development of innovative new medicines against “undruggable targets.” $100M / Series B / Apr 13, 2026
Sidewinder Therapeutics develops bispecific antibody-drug conjugates (ADCs) aimed at treating solid tumors. Their mission is to create life-saving therapies through precision therapeutics. $137M / Series B / Apr 08, 2026
Mediar Therapeutics is a biotechnology company that develops antibody-based medicines and biologic therapies to address cancer, autoimmune diseases, and other serious health conditions. Its research platform focuses on engineering multi-specific antibodies and modular biologics that can engage multiple biological targets or pathways simultaneously,enabling precise modulation of immune responses. The company’s pipeline includes therapeutic candidates designed to activate or inhibit specific immune functions, with the goal of improving clinical outcomes in oncology and immune-mediated disorders. Mediar Therapeutics also works on scalable manufacturing processes and collaborates with scientific partners to advance its biologics from discovery through clinical development. Its approach integrates protein engineering, immunology, and translational research to create biologic medicines that address complex disease mechanisms. The company continues to refine its technology and expand its therapeutic programs to support future clinical and regulatory progress. $76M / Series B / Jan 07, 2026
AAVantgarde Bio is developing gene therapies for inherited retinal disorders. $141M / Series B / Nov 03, 2025
Crystalys Therapeutics is a clinical-stage biopharmaceutical company transforming the treatment of gout. $205M / Series A / Sep 30, 2025
Avenzo Therapeutics specializes in the development of oncology therapies for cancer treatment. $60M / Series B / Sep 04, 2025
Solu Therapeutics is a precision-medicine-focused company developing therapeutics to eliminate disease-driving cells. $41M / Series A / Apr 09, 2025
Newleos Therapeutics is a biotech startup dedicated to producing safer and more effective neuroscience medicines. $93.5M / Series A / Feb 13, 2025
See all 81 investments →

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FAQ

What does Longwood Fund invest in?

Longwood Fund invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series A and Series B stage. Most of the 81 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What round sizes does Longwood Fund invest in?

Longwood Fund typically joins rounds of $16M–$100M at Series A, $30M–$141M at Series B and $17M–$100M at Series C. These are whole funding-round sizes, not Longwood Fund's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds Longwood Fund took part in.

How do I contact Longwood Fund?

Public channels for Longwood Fund include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Longwood Fund?

The team at Longwood Fund includes Aleks Radovic-Moreno (Partner), John McCabe (Operating Partner) and Christoph Westphal (Manager), among 7 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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