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MPM Capital, VC Fund

MPM Capital

VC Fund

Cambridge, United States

MPM Capital is a healthcare investment firm that invests in companies developing therapeutic technologies in oncology. The company invests in life sciences companies that seek to cure diseases by translating science into clinical outcomes. The company prefers to invest in the biotechnology, healthcare, and life sciences sectors.

Total investments:
232
Last investment:
Lead investor:
35%
Fund size:
$850M
Last fund:

Last updated:

Industries MPM Capital invests in

BiotechnologyHealth CarePharmaceuticalTherapeuticsMedical

Stages MPM Capital invests in

Series BSeries ASeries CFunding RoundSeries D

Countries MPM Capital invests in

United StatesCanadaUnited KingdomGermanyItaly

Round sizes

Series A $10M–$80MSeries B $20M–$116MSeries C $12M–$100M

Contacts

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Round size

Series A
$10M–$80M
Series B
$20M–$116M
Series C
$12M–$100M

Investment Focus

Industry

  • Biotechnology 112 (48%)
  • Health Care 73 (31%)
  • Pharmaceutical 46 (20%)
  • Therapeutics 45 (19%)
  • Medical 36 (16%)
See all 41 industries →

Stage

  • Series B 52 (22%)
  • Series A 51 (22%)
  • Series C 39 (17%)
  • Funding Round 20 (9%)
  • Series D 17 (7%)
See all 11 stages →

Country

  • United States 117 (50%)
  • Canada 3 (1%)
  • United Kingdom 3 (1%)
  • Germany 2 (1%)
  • Italy 1 (0%)
See all 8 countries →

Team

NameTitleInvestmentsLinksEmail
David P. Ryan
David P. Ryan Medical and Scientific Advisor
Medical and Scientific Advisor Total investments: 1
Find email
Detlev Biniszkiewicz
Detlev Biniszkiewicz Executive Partner
Executive Partner Total investments: 3 Find email
Uciane Scarlett
Uciane Scarlett Principal
Principal Total investments: 4
Find email
Ansbert Gadicke
Ansbert Gadicke Managing Director and Co-Founder
Managing Director and Co-Founder Total investments: 12
Find email
Bard Geesaman
Bard Geesaman Managing Director
Managing Director Total investments: 5
Find email
See all 18 team members →

Investments

CompanyDescriptionRoundLinks
Protego Biopharma Protego Biopharma
Protego Biopharma develops therapeutics based on the clear human genetic link, excellent human safety profile, proof-of-principle efficacy. The company was founded in 2011 and is headquartered in San Diego, California. $130M / Series B / Dec 01, 2025
Reunion Neuroscience Reunion Neuroscience
Reunion Neuroscience is a clinical-stage pharmaceutical company developing therapeutic solutions for underserved mental health conditions. The Company’s lead asset, RE104, is a proprietary, novel serotonergic psychedelic compound being developed as a potential fast-acting and durable antidepressant for patients suffering from postpartum depressionand other mental health conditions. Reunion is also developing the RE200 series, which includes compounds with the potential for more selective serotonin receptor activity and reduced psychoactivity for application in more chronic treatment paradigms and indications. $133M / Series A / Sep 16, 2025
Umoja Biopharma Umoja Biopharma
Umoja Biopharma is a biopharmaceutical company developing next-generation immunotherapies intended to combat cancer. The company's treatment approach retools a patient’s immune system in vivo to direct potent anti-cancer immune cells to a patient’s tumor, augmenting the body’s natural mechanisms for fighting cancer. $100M / Series C / Jan 14, 2025
āshibio āshibio
āshibio creates treatments for rare bone and connective tissue ailments, potentially preventing symptoms or slowing their course. $40M / Series A / Jun 20, 2024
Frontier Medicines Frontier Medicines
Frontier Medicines’is a developer of a chemoproteomics platform intended to further accelerate the path to drug discovery. The company's platform integrates advanced computational approaches and machine learning to discover and pharmacologically target new binding pockets on proteins, making them accessible to small-molecule drug discovery anddevelopment, enabling patients to consume breakthrough medicines that redefine the course of debilitating diseases. $80M / Series C / Feb 22, 2024
Firefly Bio Firefly Bio
Firefly Bio specializes in Degrader Antibody Conjugates (DACs) which combine the unique strengths of ADCs with selective protein degraders. $94M / Series A / Feb 15, 2024
NextPoint Therapeutics NextPoint Therapeutics
NextPoint Therapeutics develops medications to expand the benefit of immunotherapies to cancer patients. The company offers immunotherapies for a validated checkpoint axis that is independent of PD-1/L1 and modulates both adaptive and innate immune systems to find and destroy cancer cells. $42.5M / Series B / Feb 14, 2024
AstronauTx AstronauTx
AstronauTx is a UCL spin-off, will develop medicines designed to reset the behaviour of astrocytes. $58.7M / Series A / Oct 08, 2023
Deka Biosciences Deka Biosciences
Early stage biotechnology start-up developing next generation cytokine therapeutics $20M / Series B / Sep 28, 2023
Deka Biosciences Deka Biosciences
Early stage biotechnology start-up developing next generation cytokine therapeutics $20M / Series B / Sep 28, 2023
See all 232 investments →

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FAQ

What does MPM Capital invest in?

MPM Capital invests primarily in Biotechnology, Health Care and Pharmaceutical startups, most often at Series B and Series A stage. Most of the 232 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is MPM Capital's check size?

MPM Capital typically joins rounds of $10M–$80M at Series A, $20M–$116M at Series B and $12M–$100M at Series C. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds MPM Capital participates in.

How do I contact MPM Capital?

Public channels for MPM Capital include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at MPM Capital?

The team at MPM Capital includes David P. Ryan (Medical and Scientific Advisor), Detlev Biniszkiewicz (Executive Partner) and Uciane Scarlett (Principal), among 18 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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