ARCH Venture Partners
VC Fund
Chicago, United States
ARCH Venture Partners is a VC fund in Chicago focused on Biotechnology and Health Care. ARCH invests primarily in companies co-founded by scientists and entrepreneurs, concentrating on bringing to market innovations in life sciences. They enjoy special recognition as a leader in the successful commercialization of technologies developed at academic research institutions and national laboratories. ARCH has raised ten venture funds totaling over $3 billion and has invested in the venture capital rounds for more than 150 companies. ARCH investors include corporations, pension funds, endowment funds, financial institutions, and private investors.
- Total investments:
- 475
- Last investment:
- Lead investor:
- 32%
- Fund size:
- $3B
- Last fund:
Last updated:
For AI agents: llms.txt
Industries ARCH Venture Partners invests in
Stages ARCH Venture Partners invests in
Countries ARCH Venture Partners invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
| See all 17 contacts → | |||
Round size
- Series A
- $9.1M–$213M
- Series B
- $15M–$230M
- Series C
- $15M–$167M
Investment Focus
Industry
- Biotechnology 184 (39%)
- Health Care 111 (23%)
- Therapeutics 71 (15%)
- Medical 66 (14%)
- Pharmaceutical 46 (10%)
Stage
- Series A 143 (30%)
- Series B 113 (24%)
- Series C 52 (11%)
- Series D 21 (4%)
- Funding Round 20 (4%)
Country
- United States 210 (44%)
- China 13 (3%)
- United Kingdom 5 (1%)
- Canada 2 (0%)
- Ireland 2 (0%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Cindy Bayley
Affiliate
|
Affiliate | Total investments: 0 | Find email | |
Clinton Bybee
Co-Founder and Managing Director
|
Co-Founder and Managing Director | Total investments: 19 | Find email | |
Hong Hou
Venture Partner
|
Venture Partner | Total investments: 0 | Find email | |
Keith Crandell
Co-founder & Managing Director
|
Co-founder & Managing Director | Total investments: 19 | Find email | |
Kristina Burow
Managing Director
|
Managing Director | Total investments: 26 | Find email | |
| See all 17 team members → | ||||
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Soufflé Therapeutics is a biotechnology company specializing in the development of nucleic acid medicines designed for precise delivery and targeting of disease-causing cells. The company's mission is to create potent, precise, and safe medicines that can be tailored for a broad range of diseases by leveraging breakthroughs in genetic medicineand drug delivery technology. | $135M / Series B / Oct 13, 2026 | ||
| Oratomic develops neutral-atom quantum hardware and architectures for fault-tolerant quantum computing. The company focuses on utility-scale quantum computers that use light and atoms to implement ultra-efficient quantum error correction. Its work targets applications ranging from scientific discovery to new approaches in artificial intelligenceand complex simulation. Oratomic combines expertise in quantum error correction, neutral-atom platforms, optical engineering, and machine learning. The organization aims to make fully fault-tolerant quantum computing practical for real-world use cases. | $475M / Series B / Oct 08, 2026 | ||
| At Ramona, we’re creating a high-throughput microscopy toolset to unlock a new perspective on cellular-level research. With a wider field of view and the capacity to capture data synchronously, we see more — and we see it in motion. By providing a new point of view, our technology enables researchers to make more informed decisions, faster. | $25M / Series A / Sep 22, 2026 | ||
| Encoded Therapeutics is a developer of precision gene therapies intended to provide treatment for a broad range of severe genetic disorders. The company's therapy pipeline addresses devastating genetic and acquired disorders spanning multiple disease pathways including neurocircuitry, metabolic disorders, neurodegeneration and cardiovasculardisease, enabling medical practitioners to treat patients and improve their lives. | $275M / Series F / Sep 09, 2026 | ||
| Moonwalk Biosciences is a genomic medicine startup that aims to provide a new class of precision epigenetic therapeutics. The company is working on the development of a profiling and engineering technology platform that, with the help of advanced artificial intelligence prediction, provides a comprehensive view of the epigenome in health anddisease, allowing healthcare providers to take a fresh look at how therapies are discovered and developed. | $70M / Series B / Sep 08, 2026 | ||
| Happy Health is a mission-driven technology company committed to transforming mental health awareness through the Happy Ring, the first wearable designed to measure your stress and mood 24/7. | $75M / Series A / Aug 18, 2026 | ||
| Discovering powerful new drugs from eukaryotic microbes by combining Genomics with AI and Synthetic Biology. Founded by Gregory Verdine, PhD, Rick Klausner, MD and WeiQing Zhou, MBA, LifeMine Therapeutics is headquartered in Cambridge, Massachusetts. | $188M / Series E / Aug 06, 2026 | ||
| Oratomic develops neutral-atom quantum hardware and architectures for fault-tolerant quantum computing. The company focuses on utility-scale quantum computers that use light and atoms to implement ultra-efficient quantum error correction. Its work targets applications ranging from scientific discovery to new approaches in artificial intelligenceand complex simulation. Oratomic combines expertise in quantum error correction, neutral-atom platforms, optical engineering, and machine learning. The organization aims to make fully fault-tolerant quantum computing practical for real-world use cases. | $300M / Series A / Jul 07, 2026 | ||
| Ollin Biosciences operates as a clinical-stage biopharmaceutical company dedicated to acquiring and developing best-in-disease therapies for vision-threatening diseases. | $330M / Series B / Jun 24, 2026 | ||
| Trase provides and implements complete AI agent solutions, allowing businesses to automate complicated administrative procedures and operations in a safe and secure manner. | $107M / Seed / Jun 24, 2026 | ||
| See all 475 investments → | |||
Co-Investors
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FAQ
What does ARCH Venture Partners invest in?
ARCH Venture Partners invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series A and Series B stage. Most of the 475 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What round sizes does ARCH Venture Partners invest in?
ARCH Venture Partners typically joins rounds of $9.1M–$213M at Series A, $15M–$230M at Series B and $15M–$167M at Series C. These are whole funding-round sizes, not ARCH Venture Partners's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds ARCH Venture Partners took part in.
How do I contact ARCH Venture Partners?
Public channels for ARCH Venture Partners include LinkedIn, the website linked on this profile and Facebook. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at ARCH Venture Partners?
The team at ARCH Venture Partners includes Cindy Bayley (Affiliate), Clinton Bybee (Co-Founder and Managing Director) and Hong Hou (Venture Partner), among 17 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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