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Alexandria Venture Investments, VC Fund

Alexandria Venture Investments

VC Fund

Pasadena, United States

Alexandria Venture Investments is a venture capital firm that develops work in real estate technology, and healthcare sectors. The company's strategic venture capital platform is Alexandria Venture Investments. Since its inception in 1996, the company has invested in disruptive life science, agrifood tech, and technology companies that are developing transformative new modalities and platforms to meaningfully improve human health.

Total investments:
299
Last investment:
Lead investor:
8%

Last updated:

Industries Alexandria Venture Investments invests in

BiotechnologyHealth CareTherapeuticsMedicalLife Science

Stages Alexandria Venture Investments invests in

Series ASeries BSeries CSeedVenture - Series Unknown

Countries Alexandria Venture Investments invests in

United StatesCanadaFranceSwitzerlandChina

Round sizes

Series A $12M–$100MSeries B $25M–$150MSeries C $22M–$140M

Contacts

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Round size

Series A
$12M–$100M
Series B
$25M–$150M
Series C
$22M–$140M

Investment Focus

Industry

  • Biotechnology 200 (67%)
  • Health Care 108 (36%)
  • Therapeutics 96 (32%)
  • Medical 58 (19%)
  • Life Science 52 (17%)
See all 59 industries →

Stage

  • Series A 110 (37%)
  • Series B 67 (22%)
  • Series C 31 (10%)
  • Seed 30 (10%)
  • Venture - Series Unknown 13 (4%)
See all 13 stages →

Country

  • United States 206 (69%)
  • Canada 4 (1%)
  • France 4 (1%)
  • Switzerland 2 (1%)
  • China 1 (0%)
See all 8 countries →

Team

NameTitleInvestmentsLinksEmail
Daniel J. Ryan
Daniel J. Ryan Co-Chief Investment Officer & Regional Market Director –San Diego
Co-Chief Investment Officer & Regional Market Director –San Diego Total investments: 0
Find email
Dean A. Shigenaga
Dean A. Shigenaga Co-President & Chief Financial Officer
Co-President & Chief Financial Officer Total investments: 0 Find email
Joel Marcus
Joel Marcus Executive Chairman & Founder
Executive Chairman & Founder Total investments: 9
Find email
Peter M. Moglia
Peter M. Moglia Co-Chief Executive Officer
Co-Chief Executive Officer Total investments: 0
Find email
Stephen A. Richardson
Stephen A. Richardson Co-Chief Executive Officer
Co-Chief Executive Officer Total investments: 0 Find email

Investments

CompanyDescriptionRoundLinks
BigHat is a developer of an AI-guided protein therapeutic platform used to integrate antibody characterization lab with machine learning technologies to engineer molecules with more complex functions and better biophysical properties. The company is applying these design capabilities to develop new generations of safer and more effective treatmentsfor patients suffering from today’s most challenging diseases. $75M / Series C / Sep 24, 2026
Leal Therapeutics develops novel therapeutics for patients. $30M / Series A / Aug 17, 2026
Khartis is a drug discovery company developing oral therapies for patients with immune-mediated and chronic diseases. The company focuses on discovering and developing drug candidates intended to address chronic conditions and immune-mediated diseases. $50M / Series B / Aug 13, 2026
Triveni Bio is at the forefront of human genetics, cutting-edge antibody design, and precision medicine, pioneering the identification of new disease targets. $65M / Series C / Jun 17, 2026
Vedana Therapeutics is a Seattle biotechnology company developing next-generation antibody therapies for migraine prevention. $46M / Series A / Jun 17, 2026
Myeloid Therapeutics is an immunology company focused on combining immunologic insights with cutting-edge technologies to harness myeloid cells to eradicate cancer and other diseases. The Company's ATAKTM platform technology can be broadly applied, and it is initially advancing a cell therapy program for T cell lymphoma and a primed monocyteapproach to treat glioblastoma. The ATAK platform is scalable to multiple treatment modalities and other disease areas in collaboration with partners. $122M / Series B / May 14, 2026
Fathom Therapeutics, previously known as Atommap, is a biotechnology company focused on designing therapeutic molecules through computational drug discovery approaches. The company develops models that simulate biomolecular and protein motion to better understand how proteins behave and interact, enabling the identification of new therapeuticstrategies. Its platform combines generative design, predictive modeling, and computational assays to create and evaluate molecular candidates for their binding affinity and functional effects. By leveraging these simulations, it supports drug discovery processes such as hit identification, lead optimization, and the design of targeted molecules, including degraders and molecular glues. The company also collaborates with partners by providing molecular designs, predictive insights, and co-development opportunities for advancing therapeutic candidates. $47M / Series A / Apr 27, 2026
Alloy Therapeutics makes medicine by democratizing access to foundational drug discovery platforms and services. Alloy-Gx, its first platform, is a royalty-free suite of immunocompetent transgenic mice enabling best-in-class in vivo human antibody discovery. Founded in 2017, Alloy Therapeutics is headquartered in Lexington, Massachusetts. $40M / Series E / Apr 15, 2026
Neomorph is building a leading protein degradation entity, focused on “molecular glue” degraders. Its mission is to use this technology to solve critical problems in human health with the discovery and development of innovative new medicines against “undruggable targets.” $100M / Series B / Apr 13, 2026
Sidewinder Therapeutics develops bispecific antibody-drug conjugates (ADCs) aimed at treating solid tumors. Their mission is to create life-saving therapies through precision therapeutics. $137M / Series B / Apr 08, 2026
See all 299 investments →

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FAQ

What does Alexandria Venture Investments invest in?

Alexandria Venture Investments invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series A and Series B stage. Most of the 299 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What round sizes does Alexandria Venture Investments invest in?

Alexandria Venture Investments typically joins rounds of $12M–$100M at Series A, $25M–$150M at Series B and $22M–$140M at Series C. These are whole funding-round sizes, not Alexandria Venture Investments's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds Alexandria Venture Investments took part in.

How do I contact Alexandria Venture Investments?

Public channels for Alexandria Venture Investments include LinkedIn and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Alexandria Venture Investments?

The team at Alexandria Venture Investments includes Daniel J. Ryan (Co-Chief Investment Officer & Regional Market Director –San Diego), Dean A. Shigenaga (Co-President & Chief Financial Officer) and Joel Marcus (Executive Chairman & Founder). The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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