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The Column Group, VC Fund

The Column Group

VC Fund

San Francisco, United States

The Column Group is a venture capital firm dedicated to creating the next generation of biotechnology companies. They manage over $4 billion in assets and focus on building companies with groundbreaking scientific platforms that have the potential to deliver significant new therapies for unmet medical needs. TCG takes a long-term approach, aiming to develop companies capable of generating multiple product opportunities rather than focusing on quick exits.

Total investments:
165
Last investment:
Lead investor:
38%
Fund size:
$100M
Last fund:

Last updated:

Industries The Column Group invests in

BiotechnologyHealth CareTherapeuticsMedicalPharmaceutical

Stages The Column Group invests in

Series ASeries BSeries CSeries DVenture - Series Unknown

Countries The Column Group invests in

United States

Round sizes

Series A $15M–$102MSeries B $22M–$120MSeries C $37M–$120M

Contacts

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Round size

Series A
$15M–$102M
Series B
$22M–$120M
Series C
$37M–$120M

Investment Focus

Industry

  • Biotechnology 47 (28%)
  • Health Care 34 (21%)
  • Therapeutics 29 (18%)
  • Medical 18 (11%)
  • Pharmaceutical 13 (8%)
See all 15 industries →

Stage

  • Series A 37 (22%)
  • Series B 33 (20%)
  • Series C 18 (11%)
  • Series D 8 (5%)
  • Venture - Series Unknown 8 (5%)
See all 11 stages →

Team

NameTitleInvestmentsLinksEmail
David Goeddel
David Goeddel Managing Partner
Managing Partner Total investments: 16
Find email
Jeff Goater
Jeff Goater Venture Partner
Venture Partner Total investments: 8
Find email
Joseph Goldstein
Joseph Goldstein Science Partner
Science Partner Total investments: 0 Find email
Millie Ray
Millie Ray Partner
Partner Total investments: 5
Find email
Peter Svennilson
Peter Svennilson Managing Partner and Founder
Managing Partner and Founder Total investments: 19
Find email
See all 18 team members →

Investments

CompanyDescriptionRoundLinks
Kallyope, we believe that the gut is the gateway to our internal world. Containing millions of neurons, the gut informs our brains about our well-being, metabolism, and nutritional state. The gut-brain axis the communication highway between our gut and our brain offers an unprecedented opportunity to access and influence brain centers involved infundamental human processes. An understanding of the biology mediated by the gut and gut-brain circuits will change the way we think about food, nutrition, and human physiology. $94M / Venture - Series Unknown / Oct 01, 2026
Circle Pharma is an early-stage biotechnology company applying proprietary computational design algorithms and innovative chemistry to develop cell-permeable macrocycle peptide therapeutics against important clinical targets. It does this through an iterative, rational design process that deploys large virtual libraries of conformationally diversemacrocycle scaffolds selected for inherent permeability. The company was founded by Matt Jacobson and Scott Lokey in 2012 and is headed by David J. Earp. $92.5M / Series E / Sep 16, 2026
InduPro is a biotechnology company that specializes in protein therapeutics and cell-surface platform technologies. $77M / Series B / Aug 12, 2026
Nura Bio revolutionizes the treatment of neurological diseases with novel, life-changing neuroprotective medicines. Nura Bio was conceived in 2018 by The Column Group and its scientific founders. $73.8M / Series B / Jun 22, 2026
Tortugas Neuroscience is a neurology-focused biotech company dedicated to developing effective medicines that address diseases of the brain. $106M / Series A / Apr 21, 2026
Atavistik Bio is a biotechnology company that specializes in the discovery and development of precision allosteric small molecules aimed at treating metabolic diseases and cancer. The company aims to revolutionize therapeutic approaches by focusing on selective allosteric therapeutics, which can potentially transform treatment options for seriousdiseases. $40M / Series B / Mar 05, 2026
Atavistik Bio is a biotechnology company that specializes in the discovery and development of precision allosteric small molecules aimed at treating metabolic diseases and cancer. The company aims to revolutionize therapeutic approaches by focusing on selective allosteric therapeutics, which can potentially transform treatment options for seriousdiseases. $120M / Series B / Dec 18, 2025
Tr1x develops cellular therapies intended for the treatment of autoimmune disorders. $50M / Venture - Series Unknown / Oct 14, 2025
NILO Therapeutics is a biotechnology and therapeutics company. $101M / Series A / Oct 08, 2025
Neurona Therapeutics is a pre-clinical stage biotechnology company that was founded by four neuroscientists and stem cell pioneers at The University of California, San Francisco. They are focused on the discovery and development of cell-based therapies to treat intractable neurological disease. Its initial aim is to generate therapeuticcompositions of a specific type of nerve cell (or neuron) for targeted delivery into the injured nervous system. Based on nearly two decades of research, they believe that particular subpopulations of neurons have the unique ability to integrate and repair dysregulated neural circuits. Its talented team of scientists, scientific advisors, and board directors is working to accelerate breakthrough treatments for patients with significant unmet medical needs. $102M / Series F / Apr 03, 2025
See all 165 investments →

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FAQ

What does The Column Group invest in?

The Column Group invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series A and Series B stage. Most of the 165 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What round sizes does The Column Group invest in?

The Column Group typically joins rounds of $15M–$102M at Series A, $22M–$120M at Series B and $37M–$120M at Series C. These are whole funding-round sizes, not The Column Group's own check, which is rarely disclosed: the 10th–90th percentile of the confirmed public funding rounds The Column Group took part in.

How do I contact The Column Group?

Public channels for The Column Group include LinkedIn and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at The Column Group?

The team at The Column Group includes David Goeddel (Managing Partner), Jeff Goater (Venture Partner) and Joseph Goldstein (Science Partner), among 18 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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