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Foresite Capital, VC Fund

Foresite Capital

VC Fund

San Francisco, United States

Foresite Capital is a healthcare and life sciences investment firm. They take a data-driven approach to invest in startups that employ biology and big data to improve healthcare, such as 10x Genomics, Relay Therapeutics, Element Biosciences, and Inscripta.

Total investments:
223
Last investment:
Lead investor:
29%
Fund size:
$900M
Last fund:

Last updated:

Industries Foresite Capital invests in

BiotechnologyHealth CareTherapeuticsMedicalLife Science

Stages Foresite Capital invests in

Series BSeries CSeries APost-IPO EquitySeries D

Countries Foresite Capital invests in

United StatesUnited KingdomChinaAustraliaCanada

Round sizes

Series A $17M–$165MSeries B $25M–$140MSeries C $37M–$270M

Contacts

NameEmailPhoneSocials
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Round size

Series A
$17M–$165M
Series B
$25M–$140M
Series C
$37M–$270M

Investment Focus

Industry

  • Biotechnology 99 (44%)
  • Health Care 80 (36%)
  • Therapeutics 41 (18%)
  • Medical 37 (17%)
  • Life Science 27 (12%)
See all 36 industries →

Stage

  • Series B 46 (21%)
  • Series C 38 (17%)
  • Series A 26 (12%)
  • Post-IPO Equity 19 (9%)
  • Series D 14 (6%)
See all 14 stages →

Country

  • United States 99 (44%)
  • United Kingdom 6 (3%)
  • China 2 (1%)
  • Australia 2 (1%)
  • Canada 1 (0%)
See all 10 countries →

Team

NameTitleInvestmentsLinksEmail
Dorothy Margolskee
Dorothy Margolskee Managing Director
Managing Director Total investments: 1
Find email
James Tananbaum
James Tananbaum Founder and CEO
Founder and CEO Total investments: 32
Find email
Partner Total investments: 1
Find email
Dennis D. Ryan
Dennis D. Ryan CFO & Managing Director
CFO & Managing Director Total investments: 0
Find email
Elizabeth Liz Canis Senior Advisor
Senior Advisor Total investments: 4
Find email
See all 8 team members →

Investments

CompanyDescriptionRoundLinks
Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases. The company focuses on shuttled monoclonal antibodies that cross the blood-brain barrier to reach central nervous system targets. Its lead program, KRSA-028, is an investigational anti-amyloid beta antibody for Alzheimer’s disease that uses a transferrinreceptor-based shuttle and Fc engineering to improve brain delivery and dosing. Korsana is also advancing additional THETA-based programs for undisclosed neurodegenerative indications. $380M / Post-IPO Equity / Sep 08, 2026
Thyme Care is a healthcare company that provides oncology care management services. The company offers a patient- and provider-integrated oncology solution, partnering with health plans to facilitate whole-person care for their members. Thyme Care seeks to revolutionize cancer care by providing personalized and holistic support to patients. Thecompany envisions a future where every cancer patient can access high-quality, individualized care that meets their unique needs and circumstances. $125M / Series E / Sep 02, 2026
Khartis is a drug discovery company developing oral therapies for patients with immune-mediated and chronic diseases. The company focuses on discovering and developing drug candidates intended to address chronic conditions and immune-mediated diseases. $50M / Series B / Aug 13, 2026
Stepful is an online learning platform that provides training programs for entry-level healthcare careers such as medical assistant, pharmacy technician, dental assistant, and related roles. It delivers its courses through live, instructor-led virtual classes, interactive assignments, and structured exam preparation for nationally recognizedcertifications. The platform also includes in-person clinical or externship components arranged through partner healthcare providers to help students gain practical experience. Stepful supports learners with additional services such as career coaching, resume preparation, and job search assistance after certification. Overall, it is designed to help students transition into healthcare roles by combining online instruction with hands-on training and employment support. $55M / Series C / Jun 08, 2026
Cortexyme is a clinical stage pharmaceutical company developing therapeutics based on data supporting a new theory of the cause of Alzheimer's and other degenerative disorders. Cortexyme is targeting a specific, undisclosed pathogen tied to neurodegeneration. The target has been validated in a number of animal models and Cortexyme is currentlytesting several potential lead therapeutics in preclinical studies. $115M / Post-IPO Equity / May 18, 2026
GH Research PLC is a clinical-stage biopharmaceutical company dedicated to transforming the treatment of psychiatric and neurological disorders. GH Research PLC's initial focus is on developing its novel and proprietary 5-MeO-DMT therapies for the treatment of patients with Treatment-Resistant Depression. $117.5M / Post-IPO Equity / Apr 29, 2026
OnKure is a biotechnology company that commercializes a new cancer therapy based on novel, less toxic kinase inhibitor drugs. The company is engaged in the discovery and development of epigenetic therapies for the treatment of cancer that includes selective inhibitors of histone deacetylases. In pre-clinical models of both hematological and solidtumor cancers, their lead candidate, OKI-179, significantly and safely reduces the growth rate of tumors when dosed by itself or in combination with other targeted therapies.OnKure advances the HDAC3 selective inhibitor OKI-422 into pre-clinical toxicology studies. The company's drug candidates aim to treat patients by targeting malignant cells directly, by working in combination with other small molecule therapies and by priming the tumor microenvironment such that checkpoint inhibition is optimized. $150M / Post-IPO Equity / Mar 27, 2026
Pinnacle Medicines is a peptide drug discovery company that provides peptide modality for medical needs. $89M / Series B / Mar 26, 2026
Candid Therapeutics is a biotechnology company that focuses on the treatment of a range of immunological conditions. $505M / Mar 02, 2026
Slate Medicines is a biotechnology company that develops therapeutics that target Pituitary Adenylate Cyclase-Activating Polypeptide for migraine treatment and prevention. The company aims to revolutionize migraine prevention for patients seeking alternative solutions. $130M / Series A / Feb 24, 2026
See all 223 investments →

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FAQ

What does Foresite Capital invest in?

Foresite Capital invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series B and Series C stage. Most of the 223 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is Foresite Capital's check size?

Foresite Capital typically joins rounds of $17M–$165M at Series A, $25M–$140M at Series B and $37M–$270M at Series C. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Foresite Capital participates in.

How do I contact Foresite Capital?

Public channels for Foresite Capital include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Foresite Capital?

The team at Foresite Capital includes Dorothy Margolskee (Managing Director), James Tananbaum (Founder and CEO) and Stephen C. Peterson (Partner), among 8 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Sep 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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