Biotechnology Value Fund
VC Fund
San Francisco, United States
Biotechnology Value Fund is a San Francisco-based private investment partnership specializing in fundamentally-driven public biotechnology investments.Since its inception in 1993, BVF has strived to build concentrated, long-term investments in small-cap biotechnology companies while performing rigorous diligence and on-going monitoring of itsinvestments.BVF is committed to working with its portfolio companies as partners in their successes.
- Total investments:
- 179
- Last investment:
- Lead investor:
- 30%
- Last fund:
Last updated:
For AI agents: llms.txt
Industries Biotechnology Value Fund invests in
Stages Biotechnology Value Fund invests in
Countries Biotechnology Value Fund invests in
Round sizes
Contacts
| Name | Phone | Socials | |
|---|---|---|---|
| See all 8 contacts → | |||
Round size
- Series A
- $8.9M–$177M
- Series B
- $40M–$140M
- Post-IPO Equity
- $16M–$200M
Investment Focus
Industry
- Biotechnology 118 (66%)
- Health Care 70 (39%)
- Therapeutics 60 (34%)
- Pharmaceutical 43 (24%)
- Medical 39 (22%)
Stage
- Post-IPO Equity 56 (31%)
- Series B 43 (24%)
- Series A 24 (13%)
- Series C 14 (8%)
- Venture - Series Unknown 5 (3%)
Country
- United States 102 (57%)
- Switzerland 5 (3%)
- Canada 3 (2%)
- Israel 3 (2%)
- United Kingdom 2 (1%)
Team
| Name | Title | Investments | Links | |
|---|---|---|---|---|
Gorjan Hrustanovic
Managing Director
|
Managing Director | Total investments: 8 | Find email | |
James Kratky
Chief Financial Officer, Chief Compliance Officer
|
Chief Financial Officer, Chief Compliance Officer | Total investments: 0 | Find email | |
Matthew Perry
Portfolio Manager
|
Portfolio Manager | Total investments: 0 | Find email | |
Michael Murray
Managing Director
|
Managing Director | Total investments: 0 | Find email | |
Sam Huang
Principal
|
Principal | Total investments: 1 | Find email | |
| See all 8 team members → | ||||
Investments
| Company | Description | Round | Links |
|---|---|---|---|
| Tyra Biosciences, Inc. is a precision oncology company focused on developing purpose-built therapies to overcome tumor resistance and improve outcomes for patients with cancer. Tyra is using its proprietary SNÅP platform, which is optimized to enable rapid and precise refinement of structural design through iterative molecular SNÅPshots, in orderto generate next-generation product candidates that are specifically designed to address acquired drug resistance and provide alternative treatment options. Tyra is initially focused on developing a pipeline of selective inhibitors of the Fibroblast Growth Factor Receptor, or FGFR, family, which are altered in approximately 7% of all cancers. Tyra’s lead product candidate, TYRA-300, is designed to selectively inhibit FGFR3, with an initial focus on patients with bladder cancer. | $400M / Post-IPO Equity / Sep 14, 2026 | ||
| Caspian Therapeutics is advancing a portfolio of small-molecule menin inhibitors, including its lead asset KO-7246, as potential disease-modifying treatments for diabetes and chronic metabolic conditions. The company's therapeutic approach focuses on restoring the body's natural insulin production capacity through selective expansion andenhanced function of pancreatic β cells. Supported by a syndicated investor base, its model centers on transforming standard clinical paradigms from symptom management to cell-level regeneration. | $50M / Seed / Sep 09, 2026 | ||
| Entera Bio is developing novel oral drugs by utilizing its proprietary cutting edge delivery technology This technology protects large molecules and peptides in the GI tract. Oral drug delivery is the most straight forward and user friendly approach to medical treatment. Entera Bio has key personnel with the relevant know how, experience andnetworks working together to enable rapid development of its products. The company has an experienced management team with more than 50 years of combined drug development experience. | $275M / Post-IPO Equity / Jul 27, 2026 | ||
| Contraline is a medical device company that has developed a proprietary injectable hydrogel platform for use in reproductive and contraceptive applications. Contraline's first product, Adam, is implanted into the vas deferens through a minimally invasive, outpatient procedure and once implanted, the gel effectively blocks sperm. Adam isnon-hormonal, designed to last years, and easily reversible. | $92.5M / Series B / Jun 02, 2026 | ||
| Q32 Bio is a biotechnology company developing treatments for patients with severe autoimmune and inflammatory diseases. Q32 Bio is addressing dysregulation to help patients take back control of their lives in diseases with few to no treatment options, or those diseases where current therapeutics provide inadequate relief.Q32 Bio consists of ateam of scientists and industry veterans with strong expertise in immunology. The team has a strong track record of discovering and developing new and innovative therapies. | $55M / Post-IPO Equity / May 26, 2026 | ||
| Sagimet Biosciences is a clinical-stage biopharmaceutical company focused on developing novel therapeutics to treat important diseases such as the liver disease NASH and specific cancers, with focus on targeting dysfunctional metabolic pathways. The company has unique expertise in FASN biology and has created a pipeline of proprietary FASNinhibitors. | $175M / Post-IPO Equity / Apr 27, 2026 | ||
| Entera Bio is developing novel oral drugs by utilizing its proprietary cutting edge delivery technology This technology protects large molecules and peptides in the GI tract. Oral drug delivery is the most straight forward and user friendly approach to medical treatment. Entera Bio has key personnel with the relevant know how, experience andnetworks working together to enable rapid development of its products. The company has an experienced management team with more than 50 years of combined drug development experience. | $10M / Post-IPO Equity / Apr 02, 2026 | ||
| Ambrosia Biosciences offers drug development services for small molecule-based therapies for obesity and other metabolic disorders. | $100M / Series B / Mar 31, 2026 | ||
| OnKure is a biotechnology company that commercializes a new cancer therapy based on novel, less toxic kinase inhibitor drugs. The company is engaged in the discovery and development of epigenetic therapies for the treatment of cancer that includes selective inhibitors of histone deacetylases. In pre-clinical models of both hematological and solidtumor cancers, their lead candidate, OKI-179, significantly and safely reduces the growth rate of tumors when dosed by itself or in combination with other targeted therapies.OnKure advances the HDAC3 selective inhibitor OKI-422 into pre-clinical toxicology studies. The company's drug candidates aim to treat patients by targeting malignant cells directly, by working in combination with other small molecule therapies and by priming the tumor microenvironment such that checkpoint inhibition is optimized. | $150M / Post-IPO Equity / Mar 27, 2026 | ||
| Immunic, Inc. is a clinical-stage biopharmaceutical company with a pipeline of selective oral immunology therapies focused on treating chronic inflammatory and autoimmune diseases. The company is developing three small molecule products: its lead development program, IMU-838, a selective immune modulator that inhibits the intracellular metabolismof activated immune cells by blocking the enzyme DHODH and exhibits a host-based antiviral effect, is currently being developed as a treatment option for multiple sclerosis, ulcerative colitis, Crohn's disease, and primary sclerosing cholangitis. IMU-935, a selective inverse agonist of the transcription factor RORγt, is targeted for development in psoriasis, castration-resistant prostate cancer and Guillain-Barré syndrome. IMU-856, which targets the restoration of the intestinal barrier function, is targeted for development in diseases involving bowel barrier dysfunction. | $400M / Post-IPO Equity / Feb 13, 2026 | ||
| See all 179 investments → | |||
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FAQ
What does Biotechnology Value Fund invest in?
Biotechnology Value Fund invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Post-IPO Equity and Series B stage. Most of the 179 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
What is Biotechnology Value Fund's check size?
Biotechnology Value Fund typically joins rounds of $8.9M–$177M at Series A, $40M–$140M at Series B and $16M–$200M at Post-IPO Equity. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Biotechnology Value Fund participates in.
How do I contact Biotechnology Value Fund?
Public channels for Biotechnology Value Fund include LinkedIn and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.
Who are the partners at Biotechnology Value Fund?
The team at Biotechnology Value Fund includes Gorjan Hrustanovic (Managing Director), James Kratky (Chief Financial Officer, Chief Compliance Officer) and Matthew Perry (Portfolio Manager), among 8 team members tracked by Shizune. The Team section lists each member with their title, investment count and links.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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