Tuff Yen
CEO @ Seraph Group
San Francisco, United States
Tuff Yen is a seed investor at Seraph Group in San Francisco focused on Health Care and Software. Tuff Yen is the CEO of Seraph Group, a professionally managed angel investment fund group that invests in seed and early stage private enterprises by leveraging its proprietary network of more than 300 successful business leaders and entrepreneurs.Yen spent his career as a scientist and a professional investor. He worked as a venture capitalistwith Hambrecht & Quist's venture fund ("HQAP") in San Francisco as well as Chemical Bank’s venture arm in New York City. During this period, he worked on investments in a broad range of businesses including industrial manufacturing, distribution, entertainment, publishing, information technology, Internet, medical and life sciences. Prior to joining the VC community, Yen was a bioengineer with Genentech and worked at Amgen, two leading biotechnology pioneers. He received his Masters in Business Administration from the Yale School of Management and his Bachelor degree in Arts in Microbiology and Immunology from the University of California Berkeley.
- Total investments:
- 10
- Last investment:
- Lead investor:
- 0%
Last updated:
For AI agents: llms.txt
Industries Tuff Yen invests in
Stages Tuff Yen invests in
Countries Tuff Yen invests in
Investment Focus
Industry
- Health Care 3 (30%)
- Software 2 (20%)
- News 1 (10%)
- AgTech 1 (10%)
- Drones 1 (10%)
Stage
- Seed 3 (30%)
- Series A 2 (20%)
- Series B 2 (20%)
- Angel 1 (10%)
- Pre-Seed 1 (10%)
Country
- United States 8 (80%)
- New Zealand 1 (10%)
Investments
| Company | Description | Round | Links |
|---|---|---|---|
Hubble Network
|
a Satellite network connecting billions of bluetooth devices. GLOBALLY. | $70M / Series B / Sep 17, 2025 | |
Cropsy Technologies
|
Cropsy's mission is to deliver disruptive, scalable technology to every fruit grower to unlock the full potential of their land with insights that were impossible before. Our proprietary AI-enabled hardware allows growers to monitor every plant, understand the whole crop, and track how it changes over time. These insights help growers optimiseall their decision making. The system is a simple tractor add-on, so growers do all their daily operations while Cropsy looks out for problems. Cropsy is poised to set the new gold standard for growing, with recommendations, forecasts, and providing certainty to every grower, every season. | $1M / Seed / Oct 04, 2023 | |
Natilus
|
Natilus is a large scale drone manufacturing company. The company specializes in the manufacturing of Boeing 747 sized drones which provides inter-continental cargo delivery services and helps in reducing air freight costs. Natilus was founded by LZ Zhang, Anatoly Starikov and Aleksey Matyushev in 2016.First flight of their 2200 lbs / 30 ftdrone is scheduled for Summer 2018. At the end of 2018, Natilus completed a flight test of their 2200 lbs prototype.The first production vehicle scheduled for 2020 customer delivery underwent wind tunnel testing in April, 2019. Natilus currently holds an aircraft order book rumored to be in excess of $1B+. | Seed / May 18, 2021 | |
LiteraSeed
|
LiteraSeed has developed a clinically validated digital health platform that enables providers to better understand health status in low health literate patient populations, preventing costly misdiagnoses, adverse events, and ER admissions. | $110K / Pre-Seed / Sep 01, 2020 | |
Zeto
|
Zeto is a commercial stage medical technology startup transforming the way EEG (Electroencephalography) is done at hospitals. We are solving a problem unsolved since EEG was invented in 1924, i.e., an archaic, tedious approach that consumes time, requires a trained technician and puts the patient through a poor experience.Our product is the firstFDA cleared wireless, zero-prep, easy-to-wear headset with dry electrodes. The device is backed by a digital platform that offers instant upload, tools for analysis, and remote interpretation by neurologists. A process that takes over 30 mins by a technician just to set up will instead take just 5 minutes from putting on the headset to interpretable EEG.Zeto has won several awards including $350,000 from the Epilepsy Foundation, 2018 MedTech Innovator Showcase company, 2018 Exponential Medicine MEDY Outstanding Pitch Award, 2017 Rosenman Innovator by UCSF's QB3. | $7M / Series A / Feb 01, 2020 | |
Syntiant
|
Syntiant is moving artificial intelligence and machine learning from the cloud to edge devices. Syntiant’s advanced chip solutions merge deep learning with semiconductor design to produce ultra-low-power, high performance, deep neural network processors for always-on applications in battery-powered devices, such as smartphones, smart speakers,earbuds, hearing aids, and laptops. | Series B / Oct 24, 2018 | |
|
Syntiant
|
Syntiant is moving artificial intelligence and machine learning from the cloud to edge devices. Syntiant’s advanced chip solutions merge deep learning with semiconductor design to produce ultra-low-power, high performance, deep neural network processors for always-on applications in battery-powered devices, such as smartphones, smart speakers,earbuds, hearing aids, and laptops. | Series A / May 09, 2018 | |
AreaMetrics
|
AreaMetrics was acquired by Point Inside in January 2020. AreaMetrics provides geo-location data that powers insights for marketers and brands. We access a network of in-store sensors to understand offline foot-traffic and to deliver the highest-quality in alternative data intelligence. | $225K / Angel / Feb 01, 2014 | |
Primeloop
|
Primeloop makes it easy to track your press, and receive notifications about new comments, shares and engagement on all your PR clippings. | $300K / Seed / Jan 24, 2014 | |
Rallyon
|
Rallyon scales health for the enterprise.Companies use our platform to deliver health and wellness programs to their employees, allowing them to build healthier populations and in return, lower their healthcare costs.Rallyon’s new approach to motivating employees solves the 2 biggest challenges companies have: few employees participate inthese programs, and when they do, fewer see results. | $1.5M / Jun 17, 2011 |
Co-Investors
Sunstone Management
3 deals together
Embark Ventures
2 deals together
Seraph Group
2 deals together
Amazon Alexa Fund
1 deal together
Angel Investors Marlborough
1 deal together
Aphelion Capital
1 deal together
About Seraph Group
Seraph Group is an angel investor that invests between $50,000 and $1,000,000 in early-stage startups.
Seraph Group Contacts
| Name | Phone | Socials | |
|---|---|---|---|
Peter Truwit
Partner
|
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Stephen Fleming
Investment Committee
|
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Tuff Yen
CEO
|
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Charles Ralston
Principal
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Jake Moilanen
General Partner
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FAQ
What does Tuff Yen invest in?
Tuff Yen invests primarily in Health Care, Software and News startups, most often at Seed and Series A stage. Most of the 10 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.
When did Tuff Yen last invest?
The most recent investment recorded for Tuff Yen closed in Sep 2025. Shizune tracks 10 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.
Is Shizune's investor data accurate?
Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.
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