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Square 1 Bank, VC Fund

Square 1 Bank

VC Fund

Durham, United States

Square 1 Bank is a full service commercial bank dedicated exclusively to serving the financial needs of the venture capital community and entrepreneurs in all stages of growth and expansion. Square 1's expertise, focus and strong capital base provide solid support for its clients' needs. The bank offers tailored products and solutionsaided by the latest in technological innovations. To serve its relationships, Square 1 has offices coast to coast in Austin, Boston, DC, Denver, Durham, New York, San Diego, Santa Monica, Seattle, and Silicon Valley.

Total investments:
104
Last investment:
Lead investor:
33%

Last updated:

Industries Square 1 Bank invests in

Health CareSoftwareBiotechnologySaaSMedical

Stages Square 1 Bank invests in

Debt FinancingFunding RoundPost-IPO DebtSeries ASeries B

Countries Square 1 Bank invests in

United StatesIsrael

Round sizes

Post-IPO Debt $3M–$40MDebt Financing $1.5M–$15M

Contacts

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1 more contact available

Round size

Post-IPO Debt
$3M–$40M
Debt Financing
$1.5M–$15M

Investment Focus

Industry

  • Health Care 30 (29%)
  • Software 28 (27%)
  • Biotechnology 27 (26%)
  • SaaS 18 (17%)
  • Medical 17 (16%)
See all 135 industries →

Stage

  • Debt Financing 73 (70%)
  • Funding Round 7 (7%)
  • Post-IPO Debt 7 (7%)
  • Series A 5 (5%)
  • Series B 2 (2%)
See all 9 stages →

Country

  • United States 96 (92%)
  • Israel 1 (1%)

Team

NameTitleInvestmentsLinksEmail
Patrick Oakes
Patrick Oakes EVP, CFO
EVP, CFO Total investments: 0 Find email
James Duncan
James Duncan Managing Director
Managing Director Total investments: 2
Find email
Joel Marquis
Joel Marquis Senior Vice President
Senior Vice President Total investments: 0
Find email
Matt Garrity
Matt Garrity Senior Vice President, Venture Banking
Senior Vice President, Venture Banking Total investments: 0
Find email

Investments

CompanyDescriptionRoundLinks
ShopKeep ShopKeep
Everything ShopKeep does supports growing and independent businesses. Built by and for small business owners, ShopKeep provides an intuitive, secure, iPad point-of-sale system with POS software that empowers merchants to run smarter businesses by optimizing staffing, managing inventory and accessing real time sales reports and customer informationon one seamless, cloud-based platform. With more than 25,000 customers, ShopKeep’s award-winning customer care team is available to help 24/7 and provides a robust support network for growing business owners. ShopKeep is headquartered in New York City, with offices in Portland (OR), Chicago (IL), and Belfast (NIR). $65M / Series E / Dec 11, 2018
ShopKeep ShopKeep
Everything ShopKeep does supports growing and independent businesses. Built by and for small business owners, ShopKeep provides an intuitive, secure, iPad point-of-sale system with POS software that empowers merchants to run smarter businesses by optimizing staffing, managing inventory and accessing real time sales reports and customer informationon one seamless, cloud-based platform. With more than 25,000 customers, ShopKeep’s award-winning customer care team is available to help 24/7 and provides a robust support network for growing business owners. ShopKeep is headquartered in New York City, with offices in Portland (OR), Chicago (IL), and Belfast (NIR). Debt Financing / Dec 11, 2018
ScienceLogic ScienceLogic
ScienceLogic is a provider of AI-driven monitoring solutions for hybrid cloud management. The company specializes in hybrid IT service assurance. Over 50,000 global service providers, enterprises, and government organizations rely on ScienceLogic to significantly enhance IT efficiency, optimize operations, and ensure business continuity. Thecompany is a monitoring solution that provides a comprehensive, real-time view of all IT components, whether they reside in a public cloud environment or on-premises. With hundreds of packaged management apps and custom automation capabilities, they deliver the global scale, resiliency, and automation needed to simplify the constantly evolving task of managing IT infrastructure, applications, and services. $25M / Debt Financing / Nov 05, 2018
CallRail CallRail
CallRail is a phone call tracking and analytics platform businesses use to understand which marketing campaigns drive leads and conversions. Its intuitive software helps data-driven marketers optimize the performance of their online and offline advertising campaigns, increase sales effectiveness, and improve customer retention. $15M / Debt Financing / Oct 16, 2018
Paro Paro
Paro is the alternative employment model for the future of finance work. Through technology, Paro matches businesses with the highest vetted freelance bookkeepers, accountants, financial analysts, and CFOs who provide remote, on-demand, hourly support when clients need it.The company aims to empower business professionals to work on their ownterms, from day one with Paro through retirement, providing professional expertise to young companies as well as Fortune 500 businesses. Paro vets the talent, accepting only 2% of those applying to its platform, to ensure every client receives access to deeply experienced professionals who are the best fit to solve their specific financial needs. In parallel, Paro harnesses AI to offer these finance experts the tools and insights they need to build their own businesses and enhance their professional success.Founded in 2015, the company is headquartered in Chicago, Illinois. $1.5M / Debt Financing / Oct 02, 2018
Zurex Pharma Zurex Pharma
Zurex Pharmacy is a specialty pharmacy and medical technology company with a novel antimicrobial technology platform. Their company's mission is to develop and commercialize a portfolio of new antimicrobial products designed to prevent healthcare-acquired infections with a focus on surgical site wounds and catheter-related infections.It wasfounded in 2010 and is headquartered in Middleton, Wisconsin. $9M / Series D / Jun 12, 2018
Recursion Pharmaceuticals Recursion Pharmaceuticals
Recursion is a clinical-stage biotechnology company decoding biology by integrating technological innovations across biology, chemistry, automation, data science, and engineering, with the goal of radically improving the lives of patients and industrializing drug discovery. Central to our mission is the Recursion Operating System, or Recursion OS,that combines an advanced infrastructure layer to generate what we believe is one of the world's largest and fastest-growing proprietary biological and chemical datasets and the Recursion Map, a suite of custom software, algorithms, and machine learning tools that we use to explore foundational biology unconstrained by human bias and navigate to new biological insights which may accelerate our programs. We are a biotechnology company scaling more like a technology company. $20.5M / Debt Financing / Jun 05, 2018
AllyO AllyO
As the most funded and highest valued AI for HR company worldwide; AllyO has partnered with 15% of Fortune 50 to automate talent acquisition and management. Backed by tier 1 investors such as Google, SAP, Randstad, Bain and Cervin Ventures, we’ve demonstrated hyper-growth of 4.5X year over year. AllyO’s whip-smart technology delivers smartexperiences to HR teams and the audiences they serve.HR Communication is burdened with administrative routines, complicated and outdated systems, and lack of assistive resources — leaving both HR and the workforce frustrated. AllyO offers the world’s first HR Communications Platform with AI powered chatbots that help companies reduce manual work, time, and cost to engage candidates and employees, driving employee happiness, increased retention and higher and predictable staffing levels. Employers can choose across the spectrum from having manual conversations via AllyO Connect Platform to automating end-to-end Human Capital Management using AI powered Chatbots.Recruiting Automation Bots*Text to apply *Screen & Assess talent *Scheduling interviews *Talent pool engagement *Video interviewing *Employee referralsHR Automation Bots*Onboarding & training *Pulse check-ins *Ethics hotline *Internal mobility *Exit interviewsAllyO utilizes deep workflow conversational AI by intelligently engaging with the workforce through texting, website chatboxes, WhatsApp, voice, and email. End results include a 91% conversation completion rate, 94% Talent satisfaction score, 3X more talent-at-risk or ethics violation cases reported, and 80% reduction in human effort. Our proprietary AI platform is purpose-built for enterprise organizations as AllyO actively supports 92% of systems of records for talent acquisition and HR. Plus, we implement the most robust security safeguards to comply with the latest standards and regulations like SOC2 and GDPR.For more information, please visit www.AllyO.com or contact hello@allyo.com $16M / Series A / Nov 30, 2017
ViralGains ViralGains
ViralGains is a video ad journey platform that enables marketers to engage people with relevant brand stories in the contexts that people most favor. Using the platform to engage in a two-way conversation, brands discover exactly what people want and how they feel and build a unique journey that connects highly qualified consumers with relevantmessages that generate awareness, motivate intent, and impact purchase decisions. ViralGains is headquartered in Boston, with regional offices in Chicago, Detroit, Los Angeles, San Francisco, and New York. $13.5M / Series B / Sep 21, 2017
Bizible Bizible
Bizible is the unified repository to link data from the disparate sales and marketing data stores, linking CRM, marketing, web site, ad network, and customer support information for a unified view of marketing ROI and customer LTV. It also delivers unparalleled performance insights about all revenue-generating efforts, including demand gen, inboundmarketing, account-based marketing, and outbound sales. Bizible helps marketers at more than 300 companies worldwide discover their customer journey, lead transformation, and power growth. In the first release, Bizible has partnered with Salesforce.com to create an integrated marketing analytics platform that allows you to close the loop between online marketing and revenue. $8.1M / Aug 09, 2017
See all 104 investments →

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FAQ

What does Square 1 Bank invest in?

Square 1 Bank invests primarily in Health Care, Software and Biotechnology startups, most often at Debt Financing and Funding Round stage. Most of the 104 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

What is Square 1 Bank's check size?

Square 1 Bank typically joins rounds of $3M–$40M at Post-IPO Debt and $1.5M–$15M at Debt Financing. These ranges are 10th–90th percentile round sizes calculated from confirmed public funding rounds, so they are a realistic guide to the rounds Square 1 Bank participates in.

How do I contact Square 1 Bank?

Public channels for Square 1 Bank include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

Who are the partners at Square 1 Bank?

The team at Square 1 Bank includes Patrick Oakes (EVP, CFO), James Duncan (Managing Director) and Joel Marquis (Senior Vice President). The Team section lists each member with their title, investment count and links.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Aug 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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