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Scott Rocklage, Founding Partner at 5AM Ventures

Scott Rocklage

Founding Partner @ 5AM Ventures

Menlo Park, United States

Scott Rocklage is a Series B investor at 5AM Ventures in Menlo Park focused on Biotechnology and Health Care. Scott Michael Rocklage is based out of Palm Beach Gardens, Florida and currently works as a Founding Partner for 5AM Ventures. Scott previously worked at Cubist Pharmaceuticals as a Chairman and CEO. Scott Michael Rocklage attended the University of California Berkeley.

Total investments:
13
Last investment:
Lead investor:
31%

Last updated:

Industries Scott Rocklage invests in

BiotechnologyHealth CareTherapeuticsPharmaceuticalMedical

Stages Scott Rocklage invests in

Series BSeries ASeries CSeries DPost-IPO Equity

Countries Scott Rocklage invests in

United StatesSwedenSwitzerlandUnited Kingdom

Contacts

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Investment Focus

Industry

  • Biotechnology 8 (62%)
  • Health Care 6 (46%)
  • Therapeutics 3 (23%)
  • Pharmaceutical 3 (23%)
  • Medical 2 (15%)
See all 10 industries →

Stage

  • Series B 5 (38%)
  • Series A 4 (31%)
  • Series C 2 (15%)
  • Series D 1 (8%)
  • Post-IPO Equity 1 (8%)

Country

  • United States 5 (38%)
  • Sweden 1 (8%)
  • Switzerland 1 (8%)
  • United Kingdom 1 (8%)

Investments

CompanyDescriptionRoundLinks
Nouscom is a developer of an immunotherapy platform that aims to create modified viral vector vaccines for cancer treatment. The company's platform makes use of a portfolio of engineered viral vectors that have been optimized for the efficient expression of long strings of tumor neoantigens. It also includes a toolkit for inducing broad andpotent antitumor T-cell responses, allowing patients to boost cancer-specific cellular immunity. $73.4M / Series C / Nov 14, 2023
Expansion Therapeutics is a drug discovery and development company pursuing the vast potential of small molecule medicines for RNA-mediated diseases. $80M / Series B / Sep 29, 2021
NodThera is a Cambridge (UK) headquartered biotech engaged in innate immune/ inflammasome research. Their leading project is focused on developing inhibitors of the NLRP3 inflammasome for the treatment of inflammatory and neuroinflammatory diseases. $55M / Series B / Jun 03, 2020
NodThera is a Cambridge (UK) headquartered biotech engaged in innate immune/ inflammasome research. Their leading project is focused on developing inhibitors of the NLRP3 inflammasome for the treatment of inflammatory and neuroinflammatory diseases. $40M / Series A / Jun 25, 2018
Expansion Therapeutics is a drug discovery and development company pursuing the vast potential of small molecule medicines for RNA-mediated diseases. $55.3M / Series A / Jan 03, 2018
Nouscom is a developer of an immunotherapy platform that aims to create modified viral vector vaccines for cancer treatment. The company's platform makes use of a portfolio of engineered viral vectors that have been optimized for the efficient expression of long strings of tumor neoantigens. It also includes a toolkit for inducing broad andpotent antitumor T-cell responses, allowing patients to boost cancer-specific cellular immunity. $48.8M / Series B / Nov 06, 2017
Aprea is a Swedish biotech company focusing on the discovery and development of novel anticancer compounds reactivating the tumor suppressor protein p53. The Company's lead program, APR-246, is a first-in-class small molecule drug candidate in clinical development. Aprea's main shareholder is KDev Investments AB, an investment vehicleowned by Karolinska Development AB (Nasdaq Stockholm: KDEV) and Rosetta Capital Ltd. Other shareholders include Östersjöstiftelsen, Praktikerinvest, and KCIF Co-Investment Fund KB. $50.6M / Series B / Mar 09, 2016
Pulmatrix is a clinical-stage biopharmaceutical company developing innovative inhaled therapies to address serious pulmonary and non-pulmonary disease using its patented iSPERSE™ technology. The Company's proprietary product pipeline is initially focused on advancing treatments for serious lung diseases, including Pulmazole, an inhaledanti-fungal for patients with ABPA, and PUR1800, a narrow spectrum kinase inhibitor in lung cancer. Pulmatrix's product candidates are based on iSPERSE™, its proprietary engineered dry powder delivery platform, which seeks to improve therapeutic delivery to the lungs by achieving optimal local drug concentrations and reducing systemic side effects to improve patient outcomes. $10M / Post-IPO Equity / Jun 16, 2015
Novira Therapeutics is an antiviral drug discovery company that is focused on the discovery of first-in-class antiviral therapeutics for the treatment of chronic HBV and HIV infections, two global diseases with high levels of unmet need. Novira’s oral drugs target the capsid of the virus, and offer a promising treatment option both as monotherapyand in combination with current standards of care. The company’s antivirals potentially address limitations in treating chronic HBV infection, a disease for which the only class of oral drugs available, polymerase inhibitors, are rarely curative and often require lifelong treatment, as well as in chronic HIV infection, a disease for which the continued ability of the virus to mutate inevitably leads to drug-resistant viral strains. Each of these limitations to the standard of care can potentially be addressed by capsid inhibitors which feature a new mechanism of action. $25M / Series A / Mar 24, 2013
Achaogen is a clinical stage biopharmaceutical company focused on the discovery and development of broad-spectrum antibiotics to treat multi-drug resistant bacterial infections. The company's most advanced drug candidate, ACHN-490, has demonstrated a positive safety and dosing profile in Phase 1 clinical testing and displayed broad spectrumefficacy in preclinical studies against systemic infections caused by multi-drug resistant (MDR) Gram-negative bacteria (e.g., E. coli, K. pneumoniae, and P. aeruginosa) and MRSA. In addition, the company is pursuing preclinical programs in several other areas of interest to combat the global emergence of bacterial resistance. $18.9M / Series D / Mar 22, 2013
See all 13 investments →

Co-Investors

5AM Ventures

About 5AM Ventures

VC Fund · Menlo Park, United States

5AM Ventures is a venture capital firm that offers seed- and early-stage investments to its clients. The company’s client portfolio consists of firms in the biopharmaceutical, life sciences, medical technology, and research instrument industries. 5AM Ventures was founded in 2002 by John Diekman and Andrew Schwab and is based in California.

5AM Ventures Contacts

NameEmailPhoneSocials
John Diekman
John Diekman Founder & Managing Partner
Kush Parmar
Kush Parmar Managing Partner
Mason Freeman
Mason Freeman Venture Partner
Richard J. Ulevitch
Richard J. Ulevitch Venture Partner
Scott Rocklage
Scott Rocklage Founding Partner

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FAQ

What does Scott Rocklage invest in?

Scott Rocklage invests primarily in Biotechnology, Health Care and Therapeutics startups, most often at Series B and Series A stage. Most of the 13 investments tracked by Shizune back companies in United States. The Investment Focus section breaks down every industry, stage and country in the portfolio.

How do I contact Scott Rocklage?

Public channels for Scott Rocklage include LinkedIn, X (Twitter) and the website linked on this profile. For a verified work email and phone number, create a free Shizune account — contact data is searched across 20+ sources and validated before delivery, so your outreach lands in the right inbox.

When did Scott Rocklage last invest?

The most recent investment recorded for Scott Rocklage closed in Nov 2023. Shizune tracks 13 investments in total for this profile, including round sizes, stages and portfolio companies, all sourced from confirmed public funding rounds and refreshed monthly.

Is Shizune's investor data accurate?

Yes — every stat on this profile is calculated from confirmed public funding rounds monitored across hundreds of sources since 2020. This profile was last refreshed in Oct 2026 and is updated monthly. Spotted something off? Use the “Suggest an edit” link near the top of the page.

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